LOCUS       gnlProkkaBGAIDGMK_20   13787 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BGAIDGMK_20.
ACCESSION   gnlProkkaBGAIDGMK_20
VERSION     gnlProkkaBGAIDGMK_20
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 10:20:28
            Original ID  :: gnl|Prokka|BGAIDGMK_20
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13787
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13787
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3436:3787]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3437..3787
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13787
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13787
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             282..1793
                     /locus_tag="ctg20_1"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEEIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHTLTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             1866..2933
                     /locus_tag="ctg20_2"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELTSVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPTVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             2970..3254
                     /locus_tag="ctg20_3"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(3437..3787)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_4"
                     /sec_met_domain="PqqD_RRE (E-value: 6.6e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.4e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(3885..5273)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg20_5"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5521..5916)
                     /locus_tag="ctg20_6"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVVKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(5923..6696)
                     /locus_tag="ctg20_7"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSFLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6702..7229)
                     /locus_tag="ctg20_8"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7216..8457)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 385.8; E-value:
                     4.8e-117)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg20_9"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQVGTVVTTPVVTTHQPSVPA
                     IIHTMQPAVCKDDDDIQDTEEYVEEPPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8467..9561)
                     /locus_tag="ctg20_10"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQANFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9566..10606)
                     /locus_tag="ctg20_11"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             complement(10625..11659)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_12"
                     /sec_met_domain="PF04055 (E-value: 1.3e-17, bitscore: 57.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYPLLGMTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDD
                     MTNLSLKHRELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATL
                     CVSSQVGCKMNCKFCMTGKQGYTANLTASQIINQIHSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALELLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAE
                     LMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRV
                     NLIRFHAIPGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEK
                     NNES"
ORIGIN
        1 aagattattt attcacaata gaagaagtac caccaaattt gacgaagaac cagaaatctt
       61 tttcaggaga aataaaagta agttcataat ggtgctgcat tgaattattt tttggcggag
      121 ttattctaac acttaatagt tcaaaaacag atatttctct gaccaaaaga tagaactaat
      181 gatgaattaa aagttgcaat tatggttttc ttcccacaac aaacgggaaa agtcagaaga
      241 atcatgtaca tttgtaatcc gaaaactaaa agaacatcgc aatgaaaata tttccaagca
      301 gcagtatcaa gaaattggac gcttatacca ttgagaacga acctattgca tcaatcgatc
      361 tgatggaacg tgcagcaacc gtattaacaa aagccatcac agacagatgg aatacggaaa
      421 cgccggtcac tatctttgcc ggaccgggga ataatggcgg agacgctctc gccgtagccc
      481 gcatgatggc tgaaaaagga tataaaatcg aggtatttct cttcaacacg aaaggagaac
      541 tttcacccga ctgccagacc aataaagaac tggtagaaat gatggaagaa gtaaaattcc
      601 acgaaatcag tacccaattc gtacctcccg tcctgacgcc cgatcatctg gtaatcgacg
      661 gattattcgg ttcaggcctg aacaaaccgt tgagcggtgg attcgctgcc gtagtgaaat
      721 acatcaattc ctcccctgcc atggtagtag ccatcgacat tccttccgga ctaatgggag
      781 aagaaaatac attcaacgta aaagctaata ttatccgcgc cgacgtaact ttcagtctgc
      841 aactgccgaa gctcgccttt cttttcgcag agaacactga atttgtcgga gaatgggaag
      901 tgctggatat ccaattaagc gaagacggta ttgaagagat ggagactaac tacgaaatgt
      961 tggaaataga agaaatccgt tcactcatca agccacgcaa acagtttgcc cacaagggga
     1021 acttcggcca tgcactattg attgccggtt caaaaggaat ggcaggagcc tctgttctcg
     1081 ctgcccgcgc ctgcctccgt tcgggagtag ggttgctgac tgttcatgca ccaatgtgca
     1141 acaacgacat cttgcagacc tccatacccg aagcaatcgt agaaaccgac atcaacgaaa
     1201 cctgttttgc cgtacctacc gatacggacg actatcaagc agtcggcatc ggcccgggac
     1261 tgggacgaaa cgaggaaacg gaagctgcct tgttggagca actggaacac tgccagactc
     1321 ctgttgtagt ggatgccgac gctcttaata tcctcgccaa ccaccgccat acccttaccc
     1381 acctgccgaa gggttccatc ctcaccccgc atccgaaaga actggaacgt ctgaccggca
     1441 aatgccagga ctcttacgaa cgtctgatga aggcttgcga actggcccgt gccgcccatg
     1501 tccacattat tttaaaagga gcctactccg ccatcatcac ccccgaaggt aaatgtttct
     1561 tcaacccaac cggaaatccg ggaatggcaa ccggaggtag cggtgacgta ctgaccggag
     1621 taatcctggc gctgcttgcc caaggttatc ccaccgaaga agccgctaaa atcggcactt
     1681 acattcacgg attggcgggc gatgtcgctc aaaagaagca aggaatgatc ggaatgatcg
     1741 caagcgatat tatcacctgt ctgccgacag catggcgact tgtaagcgaa taaaagttaa
     1801 gaacttacag ttttttcaat aacttcatta actttgtttt caaaaccagt taaaaagaac
     1861 cgaatatgaa aaagttgatt atagcagcag gactacttat gacaacgtcc gcctatgcac
     1921 aaaccgaagt actgacaggg gttacccgag gaaaagacta tggagtggtt tacagtcttc
     1981 ccaaaaccca aatagaactt gaaataaaag ccaacaaagt caactatact ccgggagaat
     2041 tcagcaaata tgctgatcgt tacctgcgac tgaccaatgt ctccgccgac cctgaagagt
     2101 actgggaact gactagcgta aaagtgaaat ccgtaggtgt gcccaacagc gaaacgacgt
     2161 atttcgtaaa attgaaggat aagacagtag caccgctcat ggaactgaca gaggatggca
     2221 ttgtgaaaac gatcaatgtt ccttacagca acagcagtgt aggcaaaaaa gccgctcccg
     2281 ctcccacagt cctccaaaag aaagcaaatc ctcgtgaatt cctgaccgaa gagattctga
     2341 tggctagctc taccgccaag atggccgaac tggtggctaa agaaatctat aacatccgcg
     2401 aaagcaaaaa tgccttattg cgcggacagg ctgacaatat gccttcagac ggagcacagc
     2461 ttaagattat gctcgacaat ctgaatgcac aggaagaagc catgacgcaa atgttctccg
     2521 gcacctgcaa caaggaagag agaacattca ctgtccgcct tacccctgac aaggaattta
     2581 acaatgaagt tgctttccgc ttctcgaaga agttaggtgt agttgccaac aatgatttgg
     2641 caggaactcc gttttatatc agtctgaaag acctgaaatc ggtcaagata ccacaggaag
     2701 atggtaagaa gaagaaagat ttggatggaa tcgcctacaa cgtacccgga caagctatgg
     2761 ttacattgac cgacggcaaa aagaaacttt acgaaggtga acttcctatt actcaatttg
     2821 gtgtgataga atatctggct ccggttttgt tcaacaagaa ttctaccatc aaagtttatt
     2881 ttgatccgaa tacgggagga ttgctcaaag tggacagaga agaagggaaa tagaaaaacg
     2941 agaaagtgaa cttctaaaaa acaaagaata tggttggtga aggacatgca ttcgacatga
     3001 tacgccgaat aaaagaggga cgggaagctt cccgcctacg tcgtgaacgt gctaacgaca
     3061 agttgaagca tttaaaccgt gcaaacgaac cttatccact acccaatacc actcccgaag
     3121 aaatggaacg tatcatccac gactcggaga aaaagaaaga gaaagacagc aattattttg
     3181 tttggggaac gcttattatc atgggagtcc tgatagcaat tgccgtcata ctttgggctg
     3241 tatttatcaa ataaataata ataaattcac cacagaggac acggaggaca cagaggttta
     3301 atctttttta ttcactatag agtaacacag agtctcacgt attgagaatc gtatttatcg
     3361 ctctgtttta cttgcggaaa gagagagaag aactctgtgt cctccgtgtc ctctgtggtg
     3421 aaatataaat tcctatttat gcgactggta tcaccagttt tataaatcca tctttctgca
     3481 tttgagaaag ataagccgat acacgcgact cgtagccctc ttcattttga aaatggtctg
     3541 cgagtttttc tataatctca cgaacattgc gttttccatc tatcagttcc catacagccg
     3601 taccgtgttc ttccaatttc acatgaagtt ctttcgacat tcctttcggc acaaggaagc
     3661 gttgcatcca cggatattta aaacggggaa aggagagcac aattgtctcc ccttcccttt
     3721 ctgctgtaat atgttcactg cgacagggaa tgacctctaa caggttgatt ttctctttgg
     3781 cagccatact tcttattttt tatttcagag tattcatact gatacccttt tgtttacacc
     3841 ttgatacaaa attcctttgt tactttaggt attgaatttc ccagttactt ttggatattc
     3901 gcctcttcca gaccgtatcc cttcttcttg ttctctgcct tcaacatcaa agccacaatc
     3961 agagcaagta caccaaagag agcaaaaata gtcatcggca acgtgtagtc ataagtctgt
     4021 gcaccgtcta ctaccggacc tttgcaataa gtattcaaca cccatccgat caacaaagga
     4081 acacccatca atccccagtt ctgtacccag aaaatcaatg cgtatgcggt acccaactgt
     4141 ttttccggaa taatcttcgg aacagacggc cacatagctg aaggcaccaa cgagaaggca
     4201 aatcccaata taatcatgat gatagtagca aaccaccata tattcagtat aggcagagca
     4261 aacatcgtat gcacaaaaat aagcatcact gatccgatta tcatcaatgt ggctccctta
     4321 ccgatacggt cataaagcga accgaacaac ggagtcagga taatcgcacc aatcggcaac
     4381 aatccgggaa tcgttcccgc caacttcgga tctacgttat atttctgcac catcaagtcg
     4441 gcagcatact tgataaaggg gaatacagcc gagtagaaca atacacatag taatgcaatc
     4501 aaccagaatc ctttattggt aataatatac acaatatctt tcatacggaa cggttcttcc
     4561 ggttccaatc cctctgcatc caaagaagca tccaacttct tatcatagaa agtataaagg
     4621 aaaaaagcaa tcgtacccac gcacaacata atcagacaaa acaaaatcgg agcaggaata
     4681 tttgtatgga atgtgccact ctcatccgta gatccgaaaa agtctgccaa aggaactgtc
     4741 aataccatcg ccagagttgt tccgatacgt gccgtagcca tttcaagtcc catagccaat
     4801 gccatttcct tgcccttgaa ccatttcact ataatcttgg aaacagtgat accagcaatc
     4861 tccacaccta caccaaagat agcatatccc aatgcagcca acgtcacctg tgttttaaat
     4921 ccaaagagca tggcaccttc cggaaaagta gtagaaatcg catagtattt caatccacaa
     4981 ccaaacacca tcaataagca agctcccatt ccggtgaaac gaactcccat tttgtccaaa
     5041 atgataccac cgaagatcag catcaacaag aatacgttaa accaaccgta agcgcttgtg
     5101 aagaatccat aatcaagact atcccataat agttctttct caagcatggg ttttagagga
     5161 gacattacgt cggtgaggaa atagccgcat agcatagtaa atgcgaccaa tgctagaaca
     5221 ctccatcgga gtacggcgga gtcattcaat ttctgtttca aatgttctgt cattgttata
     5281 tttaaaaaag tagttaataa tcttatacag ccaacaaagg tagttaaatc tcgtttgttt
     5341 ctatcacaaa gagattgttt ttacaagaaa aagttaagtg cggattacac tgaccacgcg
     5401 gaacattgaa aatccgtgta atctgcgtaa tccgcactta aatatcaaag aaatgcagca
     5461 tccgtctgca ccttcccatt aatggtttta ccccaaagtc ttacctgacg acggagtgaa
     5521 ttactctgct gcaggagcag gagtttcagt agccggtgcc ggagtttctg tagcaggtgc
     5581 attggtagca ggagcttcag tttgcggcgc agccgtacct gcgggtaagt tatacgggtt
     5641 agtctgttgt tctttctgtg cctgttccaa cactgcatct ttaacaactg cagaacgagg
     5701 aactacataa gcagtagcaa tgctcattac aaccataaag atggccaggc cccatgttgc
     5761 tttttccaga aagtctgtag tcttgcgtac gcccatgatg gcgttagatg aagagaaacc
     5821 agaagcaagt ccgcctcctt ttgagttctg aatcagcacg atgaaacaca tcaacaaggc
     5881 tgcaataacc attaagataa cgaataataa gtacattttt agttattttg aattagcgtt
     5941 aataatcaat ttctccaaaa atctgatttg gtctgcaaag taagcatttt tttttggata
     6001 tttcaagctt aattttttaa ttatttcaag agcttttgaa tatcgttgct gtttaacata
     6061 gatttttgcc aaagtttccg taaaacagct gtcatcttcc tcttcttcct tcatcgtttc
     6121 ttcttcggta agttcgtccg aagaggttgg cgaagatggc atttcttctc ttaaaggttt
     6181 catgcagagg ggagagtcgc tctcgctctt ttctataaag tcgtcaatca gttcgaagcc
     6241 tttgagtttg ggcgtttctt cagccggctg ttccgtggcc ggagtctcct ccaaaaggaa
     6301 agaggtgtaa tccatcgaat agtcgaaact ggtccgggca gtcacctctt cgggtactgt
     6361 ggacaagaaa gcgtcgatca atgctaatgt gcggtctacg gacggttcgt ctttcagcac
     6421 ctccgtgaga ggtactccct ttttccgtgc ctgcacatca tagcggtcac cttcaatcaa
     6481 ccggaacaac tgccgtctgt ctgcaatgta aagaactgct ttccgcagtt ctccaccgaa
     6541 actaatatca tggagaatat acagattctt cagatacagc agacgaagtg actgaaaata
     6601 cggatacctc gcaagaagat tgcgcagttc gtacaaagta tccctattca gcgtctcggg
     6661 atgctgaatc cattgttgaa agttaacaga agtcatttat attaccagtt tgctacagtt
     6721 gcattaaaaa tttggtcggt gatctcttta gacatttcag caatcaatcc gtcctgtacg
     6781 gcagtcaaca actgggtaga gtcgtaagta cggaacgcag aaaactgttg ttcaaagtct
     6841 tcggcatgat tggtgttgtt gacaaaacgc acattgacgg tgatagtcaa cttcgtctcc
     6901 gaagaataac cgtcggcaga tactgcctga ttgtactgat tgtaacctgt gatttctccg
     6961 tcaatctgca agtcggcatt ttgactcggc ttgagcagtt gcagacgggt ctgccggatg
     7021 aagatatctt tcaggtcctc attaaacttg gttgccaacg gagcatacac atactccgac
     7081 ttgatcggga agtcggctat cgaaatggtc tttaccttat cataattgat agacgatccg
     7141 ttaaacttat aggaaacagt gcacgcaatg actaccaacg gcaagccgaa cagtaacaaa
     7201 gggcgtatta ttttcttaat ccaattcata ttcttttatt tttctataaa gtgtacgctc
     7261 ggaaatattc aagtccttgg ccgcactctt ccgctttccg tgatgccttt caagtgcttt
     7321 gcgtatcatt tctttttcca cttcgtccag tgacaaagga ggttcttcta catattcttc
     7381 cgtgtcttgt atgtcgtcat catccttgca aaccgcaggc tgcatggtat gaatgatcgc
     7441 aggtaccgaa ggctggtgtg tcgtcactac cggagtagta accaccgttc ccacttgtcc
     7501 tacctgcccc acctgtccgg cacgttccgc catcaggttg tgcaccatct tcttcagctc
     7561 cgccacttcc tggcgcatat cgaacagaac agaataaaga atctcccgtt cgctctcaaa
     7621 gcctttactc tcacgcgttc ccatcagcgc gggaagacgt tgcgtatttt gtgcgggaag
     7681 ataattctgc aagatagcag cagagatctc cctgttggtt tcaatgatag atatttgctc
     7741 ggtgatgttc ttcaactgac gaacgttgcc gggccacggg taagccaata actctttctt
     7801 cgcatcctcc gtcaactgga tagcaggcat ccggtatttc tctgcaaagt ctgcggaaaa
     7861 cttacggaac aacaaaagta catcgtcacc acgttcacgc aaaggcggta tttggatagg
     7921 caccgtattc aaccggtaat ataaatcttc acggaaacgt ccttctgcaa tcgcttgtgt
     7981 cagattgaca ttggtagctg ccacaatacg aacatccgtc ttttgcactt tggacgaacc
     8041 tacttttata aactcgccac tctccaacac acggagcaaa cgcgcctggg taggcatcgg
     8101 caactcccct acttcatcaa ggaaaatagt accaccgtcg gcttcgccaa agtacccttt
     8161 ccgttcgcca atcgcaccgg taaacgcacc cttctcatgc ccgaacagtt cggaatcaat
     8221 cgtgccctcc ggaatagcac cacagttgac agcaatatac tgtccgtgct tcctccggct
     8281 atattgatga ataatctgcg gaaaactttc ttttccgact ccactttctc cggtaatcag
     8341 cacagacaaa tcggtaggag ctacctgaat ggcaacatct atggcgcgcg acaatgcttc
     8401 agtatttcca ataataccga aacgctgttt cacttgttgt atctctgctc tcgtcatcac
     8461 tcgtttttaa tcttcgtcta ctgtatccag cttcagttta tcactatcgt cacgtttctc
     8521 gtaatactgt ttacgcaacg gattggcacg agccactttt tcccgctgac gattacggaa
     8581 cacatcgatg gcaacataga ttgcctgacg gaaagaatct tcacaagcca atcccttgcc
     8641 tgcaatatcg tatgccgttc catgagccgg agaagtacgt actaccggca ggcctgccgt
     8701 atagttcacc ccgtcttcca tagccaaggc cttgaacgga gccagcccct gatcgtgata
     8761 catcgccagg ataccgtcaa aatgagtata attgcctgaa cccataaagc cgtcggccgc
     8821 ataaggaccg tagcaaagga ttcctttctc ttccatttct ttcatggcag ggataatcac
     8881 ttcctgctct tccattccca acaaaccacc gtctccggca tgaggattga gagagagcac
     8941 cgcaatacgc ggagcgccga taccgaaatc ctgtttcagg caacgatgga atatcatcag
     9001 tttctcctga atcagttctt tggtaatcgt agtcgcgatc tctctgacag ggatatgtgt
     9061 cgtcaccaaa gccacccgga agtcattctt catcaaaatc atcaatgact tatcaccatt
     9121 gcccagacgt tcttcgatat attccgtatg tccggggaaa gagaactctt ccgactgaat
     9181 cgtatgtttg ttgatcggag ctgttacgat aacgtctatc aacccttcgc gatattcttc
     9241 aatggcacgt tccaaagccc ccagcgcagc tttaccggct tcggggtcgg gtttggaaaa
     9301 ttccactttc acctcatcat ccgtacagtt caccacactc aaacggttgt accccgcttc
     9361 ggtagcagag ttgacaatgc tgaaattggc ctgtatatcc agcgctttgc gatgataagc
     9421 cgctactttc ggtgagccat aaatgatcgg agtacatagt tccaacattg tagggtcgga
     9481 aaatgtctta agaatcacct catagcccac cccgttaata tctccttggg tgatacctat
     9541 ccttatcttg ttatcttcca tgtttttatt tattagtttg ttccgcttcc ttagatgctt
     9601 ctcccaatgg aatctgcttc tgctgaactt cattcggaag tttcagtgta tacagagatg
     9661 cttccatctg gcgtaccagg ttgcgtttca ttttatcagg tgaataaaca aatatttctg
     9721 ctgtaataat tcgttggttt ttctcgtcca gacgagtatg agacacatac ggaccaccca
     9781 taaagtcgcc cttcatacgc cacaggccac gtgcttccat tgtgtagctg ttctgcacat
     9841 tgatcggacg gacatcggtc agcaaactat cggtcgacat ataaacgccc tccttgaatc
     9901 cgggaatatt ggctttcatc acggagtcac gtttgtgcac aaaatattct ttggtaaacg
     9961 tatccttgtc agtgtacgga taagagtaca tcacaaagtt acggtcggca gtacctgtgt
    10021 tggtagaagc ccagaagaaa tcatccccgg tctttgaatt agccagttcg gcatccaccc
    10081 agatgtcgca tccgaacaaa ctgtccactt tctgcgaaat gaaattactg tgtttccctt
    10141 ctagaaacgt aatctgacgg ttcatttccg cacgggtaaa gaagtcgaca atcgtctttt
    10201 tgttctcttc cacaaacttc tcgaactctt cttcgttcgg agcctggata gtcaatatca
    10261 tctgcggatt ggcatacacg tccttcgcat atttgaacga ggctttcgta tatatatcct
    10321 gtatatctac aataataatg ttacgtatca acttcagcgt agaatcataa tctttcggcg
    10381 aagtatacat aatccggaaa gaaggttccg actgcggcaa accgggcata tcagcatcga
    10441 gcgcatcatg taaagccctt ccggcagcac gatcccaaac accgtgatct actacaacca
    10501 aaagctcgta agcacgacca ctagaggtgt gatttccttt cagaccacaa gatgcaacga
    10561 caaaggctac caaagcgatg cataaaataa aagagtactt tttcatgatg ttcggtttta
    10621 tatattaact ttcattattt ttctcctgtt tcgctgtcga cagcataccg caagcggcaa
    10681 aaatatcttc gcccctggat gaacggatag tggtgaaaag tccgtgtgac gtcagataat
    10741 cacgaaaacg ggtcatcgta tccatatccg ccccctcgag gtctaccccc ggtatggcat
    10801 gaaaacgaat cagattcacc ctgcaatcca gcccgcgaag aagtttcagc aactctttgg
    10861 catagacctg cgaatcattg agccctttaa aaacaatata ttcaaacgaa agtcgacgtt
    10921 gtttactaaa atcatagttt tttaacagtt ccaccatttc ggtgattgaa aacgcctttt
    10981 ccgccggcat taattcagca cgctgaacgg tcagcggaga gtgaaggctg atggcaaggt
    11041 ggcagtcatt ttcttcaata aaacgctgca atcctttccg tagcccgact gtagaaagcg
    11101 tgatacgctt cggactccat gcgtaaccgt aggtagcggt cagtagttcc aatgccttca
    11161 atacctcatc caggttatcg agcggctcgc ccattcccat cattacgaca ttagtcagtt
    11221 tgtcccgttc cggcagcgaa tgaatctggt ttatgatctg gctggcggtc aggttagccg
    11281 tatacccctg tttaccggtc atacagaact tacagttcat cttgcaacct acttgtgacg
    11341 acacgcacaa cgttgcccgg tcatcatccg gtatataaac cgactctaca aaatggttct
    11401 cacccacttt ataaagatac ttcaccgtac catctacaga gcgcatttca tctaccggag
    11461 cttccgctcc cacctcatag ttctgcttga gcaactcccg gtgtttcaat gacaaattag
    11521 tcatatcatc aatcgaggct accttctttt cgtaaagcca ggatgcaatc tgcttggcag
    11581 caaagccggg catacccagt ctttttgtca atgattgaag ctctacaaga gtcattccta
    11641 aaaggggata tttagacatt cttctttctg ttgatagttt atatctgcaa atgtaaggaa
    11701 ataaagtcga tttccgtata gcaggaatgt aaaagttaac aaaaaaggga agtatgcctc
    11761 cgttatgatt caaccacgct gatatattga agtagctttt gcgccatttc agaatcctcg
    11821 ccattctttt tcacttcatg accgtacgcc tcacggaaac aagccagcgc ctcttcccgt
    11881 tcattacaaa agctgtgcaa aacccctaag ttctgacaag ccagaatcgt atcttcttcc
    11941 tcccatccca aatacttctt tcgcagttcg aactctctga agaaagcctc tttcgccatt
    12001 ggataattct ccaacttcac ataagcctgt gctttgtaat aatataccag acaggaagca
    12061 ttagggtcag tatcatcgtg aaaatccaaa gacgttgcaa tacgaatcac gttatcatag
    12121 tctttattca tgtaatactg ctgcataata tcacatctca atgcctcgta gcggacagtc
    12181 agttccgcca gacgcggttt ttcgctgaaa tacatttcat gcagaagaga ctcacggaag
    12241 aataaagtag atgcctgctc atcgccacgt tcattcatca tccgtttgaa ttccctgcac
    12301 agataataca actgtttatg acaagcgacg atctgttttt tactatctat ctgtatagca
    12361 atgtccaacg cctgattcat cagcatccat gcttcatcgt atcgtttgat ataataaaga
    12421 catttaccct gcatacgcaa acatttagcc actccaccgg acagtctgcc attcaacgac
    12481 tcatgcattt cagctacttt ccggaatttc tcggcagcac tctcttcctc atccttatag
    12541 taatcacaat aagccagata ttcggaaagt tcaatgactt ctgcctgact cttctcgtca
    12601 gcagaagccg catgataatc aagcgcccta ttcagataga tcactgcttc attgtattgc
    12661 tcattgtagt aatatgccag agctagattt cggcaggtgt tggcaatctc cagttccgga
    12721 gtaggtacaa tgttttcctg catcaccaat gctttcaaga aacagtcgca tgccgtttcg
    12781 tactcttcat tacgggcata gcggcatccc tcattcatct tcaataccga cttggcaatg
    12841 agtggcatgg cagcaccttc catactcttc tcactcacag cagctgccgc cttcgtcaga
    12901 tggaaagaac tgctcaagaa agtagccata tcattagcaa tgacaggaat taaaaaagaa
    12961 tcgatctcat caaagtccaa ttcggcatag acttcaggcg taacttcagg attgtcgttc
    13021 atgatcgcct tccagctatc ttccaacaga gaacgattcg tgcgatacaa aatctcgaaa
    13081 atctccacat cacaaatcca atccttcaat atatcccatt cttgcatctt atagcattga
    13141 taggtaatct ccactttata gcgatacgaa tcatggtagc agaactgttt catgcgatag
    13201 ttataatcgg caaaagtcaa cggatgggaa aggacctctt cctcatccag caaagcggaa
    13261 ataatttcat ggcgactatc atctatacat tcgtcatctt gagcgaaata gcgttcgatt
    13321 gcctctacca tttgtgtgtc accaatgcaa tatcgtcctc ctttgttggt aagccagctg
    13381 ctcatttcca ctctcaactg cgaccaaagt atctgattaa tgtctgccat gctcttcact
    13441 tcatcttcgg taaatccttc taaagtaagt gaaagcatca gaagcgttct tccaatctct
    13501 tcgaaaccat aatcagccga caaacgccgt agcacactgt catagaattg cccaacctca
    13561 ttgagccggc aatatccact catatattca ttgagagcat cgtactgacc gaacgaaacc
    13621 agctcgttga gcaatacact taaacagcgc ggttgtttag ccagcaccca cgaagcaaga
    13681 atatcttcct gttgtgcaga caaagccttg gagtaagtag acaaatattg ctttgagaac
    13741 gacttggcat ccgcctgtga aaaaccattc aactggaaat gggcgta
//
