LOCUS       gnlProkkaEIEGICHI_1    11697 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EIEGICHI_1.
ACCESSION   gnlProkkaEIEGICHI_1
VERSION     gnlProkkaEIEGICHI_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 09:28:53
            Original ID  :: gnl|Prokka|EIEGICHI_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11697
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11697
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[3176:6697]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3177..6697
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11697
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11697
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..434
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MQEYIIDYRTSKSKEDCIYLEKLFKERQQEYYVAQKKYADYMDSH
                     DNIILQSVRTEQERLQNDMSLAYQVYSQVASQLQIARAKVQEEKPVFAVVEPAVVPLEP
                     SGTSRKVCVLAFIFLSVCIVISWNLFGKDFLNKFKEVCA"
     CDS             454..1866
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 294.9; E-value:
                     1.9e-89)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2"
                     /sec_met_domain="Bac_transf (E-value: 5.7e-68, bitscore:
                     222.5, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSTTSQINKFIEFVAVLGDLIILNLVLFFLLFFWEEVFVSLPFS
                     CRVSWMMTSLSLCYLACSGSRGRVWDSRGIRPDQLVLRVLKNIIAFSIFWACIMTFSGI
                     SIYSPLFFVAYFSFLFVILSIYRIIIRHFLIVYCAKGKHRRYAVFIGGGNNMQVLYEEM
                     ESSLASSLYEVVGYFDIKPNEAFSSQCSYLGNPDGFSDFMSVHPGIKHVFCSLSMEEGR
                     YNFSIMNHCENHLLYFHGVPNVCKGFPRRIWHSMVGNMPILNLRYEPLGKMENRILKRI
                     FDIVISGLFLVTIFPFVYLIVGSIIKLTSPGPVFFKQMRTGLNGVDFVCYKFRSMKVND
                     EADSKQATADDPRKTRFGDFLRRSNIDELPQFINVFKGDMSVVGPRPHMLAHTEIYARL
                     IDKYMVRHFIKPGVTGWAQTHGFRGETRELSQMEERVKADIWYMEHWTMLLDIYIIYKT
                     VANVIVGEKNAY"
     CDS             1928..3055
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MNHYDFLIVGAGLFGSVFAYKAKLQGKKCLVIDRRSHLGGNIYCE
                     NIEGINVHKYGAHIFHTSNKVVWDFVNSIVEFNRYTNSPIASYKGKLYNLPFNMNTFYQ
                     MWGITTPAEARAKIEEQKAEAIALMKEQGVIEPRNLEEQAQLLIGKDIYESLIKGYTEK
                     QWGRKCSDLPAFIIKRLPVRFIFDNNYFNDKYQGIPIGGYNVLIERLLEGIDTKLNYDF
                     FAHRNELEEISDRIVFTGAIDEFYRYRFGKLEYRTVNFETELLNMSNYQGNAVINYTEK
                     EIPYTRVIEHKHFEMFGADIEACSKTVISKEYSSEWKEGSEPYYPVNDEKNNSLYLKYK
                     KLADQDNNVIFGGRLAEYRYYDMHQIVTKALSHFK"
     CDS             3177..4460
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 202.1;
                     E-value: 1.8e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4"
                     /sec_met_domain="CTP_transf_like (E-value: 6.5e-13,
                     bitscore: 43.7, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 4.6e-117, bitscore:
                     384.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1e-60, bitscore:
                     199.7, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSADIIHPGHLNIIHEANKLGRVVVGVLTDSAIASYKRLPYLSFE
                     QRSLIVENLKGVDEVIPQTTLDYVPNLEKIRPNYVLHGDDWKEGVQQKTRQHVIDCISQ
                     WGGKVIDIPYTQGISSSLLNQHLKEIGTTPEVRMKRLRRLIAAKPIVRILESHSGLTGL
                     IAENACIEINNVKREFDGMWASSLTDSTSKGKPDIEAVDLTTRLHGLNDALEVTTKPFI
                     YDGDTGGKLEHFVFTVRTLERLGVSAVIIEDKVGLKQNSLFGTDAIQTQDTIEGFTAKI
                     KAGKNAQITEDFMIIARCESLIAGKPMSDAIERCFAYVEAGVDGIMIHSKEKTGEDIKE
                     FCKKFRARYADIPIVVVPTTYNQFTEEELASWGINVVIYANHMLRASYPAMMNCAKSIL
                     THGRSKEASAEYCMPIKEILELIPSTHK"
     CDS             4470..5594
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 62.4;
                     E-value: 5.9e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.8e-19, bitscore:
                     64.5, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.7e-20, bitscore:
                     66.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPKFFIDELDRYGIDYFAGVPDSLLKSICGYIADNMDARHNII
                     TANEGAAVALAAGYHLATGKVGVVYMQNSGEGNAINPLASLVDKEVYNIPILLLIGWRG
                     CPGVQDEPQHVKQGKVTTGLLNIMGVNYDVLSKEENKAAKQILKAVEAVKRNEVYALII
                     EKDTFNAYTLQNVERNNFTMSREEAIQTVVAALGEADTIISTTGMISRELFEYRTAMNQ
                     GHERDFLTVGAMGHASQIALGIALEKQDRKVWCFDGDGASIMHMGSMAIVANKAPQNYV
                     HVVFNNGAHDSVGGQPTVGLKIDIPAIAKAMGYKHVYNVDTKEGLQELIGEIKVQEGPI
                     FLQACVKQGNRKDLGRPTTTPIQNKEALMTFLRS"
     CDS             5606..6697
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_6"
                     /sec_met_domain="Fe-ADH (E-value: 2.7e-66, bitscore: 218.3,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIIYQGIDYLNEALKGSTKVLLVCGSSFPYLGIKDKIEHIGTPF
                     MVFDQFTSNPLYEDICRGVDLFQITQCDTILAIGGGSSMDVAKCVKLYCQMSKDKPYLQ
                     QEYKDTGVKLIAIPTTAGSGSESTCYAVIYHDGKKQSVMHKSIIPDVVILEPKLLKTLP
                     VYQKKCTMLDALCQGIESWWSVNSTDESKRYSKIAVETIIKYWREYIFENTDFSAEQIM
                     LAANYAGRAICITQTTAAHAFSYKITSLYKLPHGHAVAVGLSEIWEYMLLNMNKCLEPR
                     GEEYLWGIFADISKAMGCLTLEQAVVKFRQILTEMEITNPVAINKTEEIEILSHSVNPV
                     RLKNNPVELCEFTIKSLYEIIIK"
     CDS             6773..7753
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MTQYINSLEEEMRSGFLVTRQSKHVWNIQIEMTLALLEVCKKYNL
                     RIWAISGTMLGAVRHKGFIPWDDDMDFFMFREDYDRLLEIASDEFKKPIFFQCAYTEKG
                     YYRGHAQMRYDNTAMILLYEGEIGVKFHQGIFIDIFVADGFPEDKEEREQLIEQRNCIL
                     NYLWGRNYPLRRFSSIPNLIKYISAKRKLGEKASWTDIELYSYMEQLHRNYSVNRNSRN
                     CCIQFTYLPRYVRNTEWFDETVWIPFERIELPVPLAYHEVLKHEYGDYMKPIKGASLHG
                     NLVVDVDESYEKYLSGLKMSFLKATYLFIKSGGGMVLRVFGLRKK"
     CDS             7778..9205
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_8"
                     /sec_met_domain="Polysacc_synt (E-value: 2.2e-38, bitscore:
                     126.8, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDKAVNGVFWTSVERIGSQVLSLLVGIAVARILSPEDYGIIGMT
                     AIFLAVASTLLDSGFGSALIQNQNRTETDYSTCFYFNIVVGLFWYVVLFLAAPLIADFY
                     RTPLLESVCRVLGLVFVFNSLTISQTARLTVEFRFRELCFVTLGTQLLTGIVGFIMAFK
                     GYGVWALVFQQVGAAFLRVCLIEWITHWKPLPLFSKIAFCRMFSFGSKILCSGIINTVY
                     DNIYTLVIGRVFSPVEVGFYNRGNQFAQLPSQSLLSVVMKVVYPLMAEVQDDSEKLCRA
                     YQKFLRISVFILYPILIGLIVLAESFIYVLLGDKWLPCVPLMQILCFSYLFDPLTHINL
                     NILYVRGRTDLVLKLELIKKPIALIILFGMLPFGLWWLCAGRALYSFIAYCFNCFYTGK
                     FIRFGFRQQMYYSVPVIVKSALMGIICWRTALGFEEPWLKLMVGFLAGLLSYIGLNFIS
                     HDESFFDIKGIILKNGK"
     CDS             9220..10236
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_9"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.9e-26,
                     bitscore: 87.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKILSVVIPSYNMEEYLYRNVSSMMIGEILDDLEIIIVNDGSKD
                     RTSEIAHELQRKASQSIVVIDKENGHYGSCVNAALKIATGKYFRILDADDWMDSGEFVK
                     FVNILKCIDVDCIYTPFANVFFNKNRKEYCIADNAVWNKKIDLSHVSLPPSYFHMHSLT
                     YRTHLLHKISFVQEEKICYTDSEYVFYPLSHAKSLYCINVCPYQYYIGREGQSVSLDSL
                     SKNYAHFEKVLANISFYKPMELLPTYSSLRKYYIVTLLRYMLDIHLFSQKKDVQRDKLL
                     RDKIRAFGDDVNISEQIKDINLKGLHYINWWLDNTGVDKLKLKILVLLKKVQHTIVN"
     CDS             10238..11203
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_10"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-26,
                     bitscore: 88.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKISVIIPVYKVEQFIERCAISLFEQTLDDIEYLFIDDCSPDNS
                     VEIIKNVLMRYETRKDSVRIISMQKNCGQAAVRRYGNSIARGDYIIHCDGDDWVDINMY
                     YKMYECAVNNKLDIVRCKFCRTDGKLMKECINIPSNIYCDAKKMISYLLRLSDLSSTCD
                     KLVRRELYQSVDFIYPVDNMCEDFAIVTQLFCRTDKIGYIDEVLYFYYQNKFSISHILD
                     NTHIDNKAQQISNNVKLIGKILKTKYPGGIFDKEIEVIKLMAKNAYRPIIRREGYYEKW
                     KTLYKEINSKIFFNEYITIKEKLSFIACYIGIYPLLTGRK"
ORIGIN
        1 aattgcagga atacatcata gattatcgta cttccaaatc taaagaggat tgtatttatt
       61 tggagaaact tttcaaagaa cgtcaacaag aatattatgt cgctcagaag aaatatgctg
      121 actatatgga ctctcatgac aatatcattt tgcagagtgt tcgtaccgaa caggaacgtt
      181 tgcagaatga tatgagcctt gcttaccagg tatacagcca ggttgccagt cagcttcaga
      241 ttgccagagc taaagttcag gaagagaagc cagtgtttgc tgttgtagaa cctgctgttg
      301 tccccttgga accttcggga accagtagga aagtatgtgt tttagctttt attttcctat
      361 cagtttgtat tgttatctct tggaatctat tcggaaaaga ttttctgaat aagttcaaag
      421 aagtatgtgc ctaaaatcaa tttttaatgt gatatggtat caaccaccag tcaaatcaat
      481 aaatttatag aatttgtagc agttctggga gatctgatca ttctgaacct ggtattgttc
      541 tttctccttt tcttttggga agaagtattt gtctctttac ctttttcttg cagggtttca
      601 tggatgatga cttcgttaag tctctgctat ctggcctgtt ctggatcccg tgggagggtg
      661 tgggatagtc ggggaattcg ccctgaccaa cttgtgttgc gtgtgttgaa gaatattata
      721 gctttttcca tcttttgggc atgtatcatg acttttagtg gaatctctat ctattctcct
      781 cttttctttg ttgcctattt ctctttcctc tttgttattc taagcattta tcgcattatt
      841 atccgtcatt tcctgatagt ctattgtgct aaaggcaagc atagacgtta tgctgttttt
      901 ataggtggag gcaataatat gcaggtgttg tatgaggaga tggagagttc tttagcctct
      961 tccctatatg aggttgtggg ttattttgat ataaaaccga atgaagcctt ttcctcccaa
     1021 tgttcctatc tgggtaatcc cgacggtttt tcagacttta tgtccgtaca tccgggaatc
     1081 aaacatgttt tttgttctct gtcgatggag gaggggcgct ataatttttc tattatgaat
     1141 cattgtgaaa accatttgct ttattttcat ggtgttccta atgtatgtaa aggttttcct
     1201 cgtcgtatct ggcacagtat ggttggcaat atgcctatct tgaatctgcg ttatgagcct
     1261 ttgggtaaaa tggaaaatcg gatattgaag cgaatatttg atattgttat ctcaggtctt
     1321 tttctggtta ctatttttcc ttttgtttat ctcatagtgg gaagtattat aaaattgact
     1381 tctcccggtc ctgtattctt taagcaaatg cgtacgggtt tgaatggtgt ggattttgtg
     1441 tgttataaat tccgttcgat gaaagtgaat gatgaagccg acagtaaaca ggctacggct
     1501 gatgatcccc gtaaaacaag atttggagat ttcctccgtc gttctaatat tgacgaactc
     1561 cctcagttta tcaatgtctt taagggtgat atgtcggtag ttggtccccg tccacacatg
     1621 ttagcccata cggagattta tgcccgtttg attgataaat atatggtgcg gcactttata
     1681 aaacctggag tgaccggttg ggctcaaacg catggttttc gtggtgaaac gagggaatta
     1741 tcacagatgg aggaacgtgt taaggctgat atctggtata tggagcactg gacaatgctg
     1801 cttgacatat atatcattta taagactgtg gcgaatgtga ttgtggggga gaagaatgcg
     1861 tattagaaga ggggatatta acgaatttaa atgtatttcg taatatagaa ataaaattag
     1921 aaatgtcatg aatcattacg atttcttaat agtaggtgcc ggactttttg gttccgtatt
     1981 cgcctataaa gcaaaactac aaggtaaaaa gtgtttagtt attgatcgcc gttctcattt
     2041 gggtgggaat atttattgtg aaaacataga aggtattaat gttcataaat atggagcaca
     2101 catttttcat acttccaata aagtagtgtg ggattttgta aattccattg tggaattcaa
     2161 tcgctatacc aattcaccga tagctagcta taaaggaaag ctgtataatt tacctttcaa
     2221 tatgaatact ttctatcaga tgtggggaat cactactcct gctgaagcaa gggcaaagat
     2281 tgaagaacag aaggcagagg cgattgctct catgaaagaa caaggtgtta ttgaacctcg
     2341 caacttggaa gagcaggcac agttacttat cggaaaggat atttatgaat cgctgattaa
     2401 gggttataca gaaaaacagt ggggacgcaa atgtagcgat cttcccgcat tcatcatcaa
     2461 acgacttcct gtacgtttta tttttgataa caactatttt aacgataaat atcagggaat
     2521 tcctatcggt ggatacaatg tactgataga gcgcttgctg gaaggtatag ataccaaact
     2581 aaactatgat ttctttgctc accggaatga gttggaagaa atttcagata ggatagtatt
     2641 tacaggagca atagatgagt tttatagata tagattcggg aagttggaat atcgtacagt
     2701 aaattttgaa acggagctat taaatatgtc caactatcag ggtaatgcag taattaatta
     2761 tacagaaaaa gaaattccct atacacgtgt cattgagcat aagcattttg aaatgttcgg
     2821 ggcggacatt gaggcttgtt ctaaaactgt tatctcgaag gaatacagtt cagaatggaa
     2881 agaagggagc gaaccttatt atccagtaaa tgacgaaaag aataattcgc tttatcttaa
     2941 atataagaaa ctggctgatc aggataacaa tgtgattttt ggaggtcgat tggcagaata
     3001 tagatattat gatatgcatc aaatagtaac aaaagcttta agccatttta aatgaaggca
     3061 tatgttaata tatctaattt ttgaaggtgt atttttatgt gattaaatat aaaaaaactg
     3121 tctatatagt attataattc aataatatgg ataagataaa aactgtttat gtcggtatga
     3181 gtgctgacat aattcacccg gggcatctca acataattca tgaggcaaat aagcttggtc
     3241 gtgttgtggt aggggtatta acggattcgg caatagctag ttacaagcgg ttgccttatc
     3301 tgtcatttga acaacgttca cttattgttg agaatctgaa aggggtggat gaagtcatac
     3361 ctcagactac tcttgattat gtaccgaatt tggagaaaat ccgtccaaat tatgttcttc
     3421 acggtgatga ttggaaagag ggggttcagc agaagacgcg tcagcatgtt atcgattgca
     3481 tttcacaatg gggaggtaag gttatagata ttccttatac tcaaggtatt tcttcttcat
     3541 tgcttaacca acatctgaaa gagataggta caacccctga agtccgaatg aaaagacttc
     3601 gccggctgat tgctgctaag cctattgtac gtattcttga aagtcattca ggacttactg
     3661 gtcttattgc ggaaaatgct tgcattgaaa ttaataatgt gaagcgtgag ttcgacggta
     3721 tgtgggcatc ttcattgacc gattctacct caaagggtaa accggatata gaggctgtcg
     3781 acttgacgac acggcttcat ggtcttaacg atgctctcga agtaactaca aaaccgttta
     3841 tttatgatgg tgatactggt ggaaaattag agcattttgt tttcactgtt cgcactttag
     3901 aacgtctggg agtttctgct gttatcattg aggataaagt gggattaaag caaaattcac
     3961 tattcggtac agacgctatt cagacacagg atactatcga aggatttaca gcaaagatta
     4021 aggcgggcaa aaatgctcag attactgaag actttatgat tatagcacgt tgtgaatcgc
     4081 ttattgcagg taagccaatg tctgatgcta ttgagcgttg ctttgcttat gtggaggctg
     4141 gtgttgatgg tatcatgatt cattcaaagg aaaaaacagg tgaggatatc aaggaattct
     4201 gtaaaaaatt tcgtgcaaga tatgcggata tacccattgt ggttgttccg acaacctata
     4261 atcagtttac agaggaggag ttggcttcat ggggaataaa tgtggtaata tatgcaaatc
     4321 acatgcttcg tgcatcttat ccagcaatga tgaattgtgc caagtctatc ttgacacatg
     4381 gtcgttcaaa agaggcttct gcagaatact gcatgcctat caaagagatt cttgaactca
     4441 tccctagtac acataaataa aataatataa tgattagtcc gaaatttttt atagacgaat
     4501 tggataggta tggtattgac tattttgcag gtgtaccgga ttcgctactg aagagtatct
     4561 gtggatacat agccgacaat atggatgcta ggcacaacat tataactgct aatgaaggtg
     4621 ctgctgttgc tcttgcggct ggttatcatt tagccacagg aaaggtaggt gttgtataca
     4681 tgcagaactc tggtgaggga aatgccataa atccattggc ttcactagta gataaggaag
     4741 tctataatat accgattctt cttctgattg gttggcgtgg ttgtcctggg gtgcaagatg
     4801 aaccacaaca tgtaaaacag ggcaaggtga caaccggatt gcttaatatt atgggagtga
     4861 actatgatgt gctttcaaaa gaagaaaaca aggctgcaaa gcaaatatta aaagctgtag
     4921 aggcggttaa acggaatgag gtctatgccc ttatcattga aaaagacacc tttaatgcct
     4981 atactcttca aaatgtagag agaaataatt ttacgatgtc tcgtgaagag gctattcaaa
     5041 cagttgtagc agcacttggt gaagctgata ctattatatc tactacaggt atgataagtc
     5101 gtgaactctt cgagtaccgt actgctatga atcaaggaca tgagcgcgat tttttgacag
     5161 taggggctat gggacatgcc tctcaaatag ctttaggcat agctttagag aagcaagatc
     5221 gcaaagtgtg gtgttttgat ggtgatggag cttctattat gcatatgggt agtatggcta
     5281 ttgtggctaa taaagcgcct cagaactatg ttcatgtagt ttttaataat ggtgctcacg
     5341 actcggtcgg aggtcagcct actgtaggtt tgaagattga tatacctgct atagctaaag
     5401 ctatggggta taaacatgtt tataatgtcg atacaaagga ggggctacaa gaattgattg
     5461 gtgaaatcaa agtccaagaa ggaccaattt tcttgcaggc atgtgtcaag cagggcaatc
     5521 gcaaggattt aggtcgtccc actactacac ctattcagaa taaggaagct ctgatgactt
     5581 ttttaaggag ttagatttat ataatatgca aataatatat caaggaattg attatcttaa
     5641 tgaagctctc aaaggttcta ccaaggtgct attagtttgt ggtagtagct ttccttatct
     5701 tggtattaag gataagatag aacatattgg tactcccttc atggtgtttg atcagtttac
     5761 ttctaatcct ctttatgaag atatctgtag gggggtagac cttttccaga ttactcaatg
     5821 cgacacaatt cttgctattg gtggtggtag ctcaatggac gtggctaaat gtgtaaagct
     5881 atattgtcaa atgtcaaaag ataagcccta tttgcagcaa gagtacaaag atactggcgt
     5941 gaaactgatt gccattccta ctacggcagg ttcagggtct gaatctacct gctatgccgt
     6001 tatttatcat gatggtaaga aacagagcgt gatgcacaaa agtattattc ctgatgtcgt
     6061 cattcttgaa ccaaagttgc tcaagactct tcccgtttat cagaagaaat gtactatgct
     6121 tgatgctctt tgtcaaggta ttgaatcttg gtggtctgtg aactccactg acgagagcaa
     6181 gcgttattcc aagatagctg ttgagacaat cataaagtat tggcgtgagt atatttttga
     6241 aaatacagac ttttcagctg aacagatcat gttggctgct aactatgctg gtcgtgccat
     6301 ttgcataact caaactacgg ccgcacatgc tttcagttat aagattactt ctctatataa
     6361 acttcctcat ggtcatgctg tggcagtagg actttcagaa atatgggaat atatgttgtt
     6421 gaacatgaac aaatgtttag aacctcgcgg tgaagaatat ctttggggca tctttgctga
     6481 catttctaaa gctatggggt gcttaacttt ggagcaagct gttgtcaagt ttcgccaaat
     6541 attgacagaa atggaaatca caaacccggt tgctattaat aagacagagg agattgaaat
     6601 tctttcccat tcagttaatc ccgttaggct gaagaataat cctgtggaac tttgcgaatt
     6661 tactattaag tctctttatg agattattat taaatagata tctatgagtt tattcaatga
     6721 ataaggagta ttaagtgatg atctaaaata atagccgttt acttacactt ttatgacaca
     6781 atatataaat tcgcttgaag aagagatgcg gagtggtttt ttggttacgc gtcaaagcaa
     6841 acacgtatgg aatatacaga tagaaatgac attggcactt cttgaggtat gtaaaaaata
     6901 taatcttcgt atatgggcaa taagtggaac gatgctggga gctgtgcggc ataaaggatt
     6961 tattccatgg gatgatgata tggatttttt tatgttcaga gaagattatg accgtttatt
     7021 agaaatagct tcggatgaat ttaaaaaacc tatattcttt cagtgtgctt atactgaaaa
     7081 aggatattat agagggcatg ctcagatgcg ttatgacaat acagctatga tattgttata
     7141 tgaaggagaa atcggcgtta aatttcatca ggggatattt atagatatat ttgtagctga
     7201 cggatttcct gaagataaag aagaaagaga acaacttata gaacagagaa actgcattct
     7261 aaattattta tggggaagaa attatcctct gagacggttc tcttccatac cgaatttgat
     7321 aaaatacatt tctgctaaac gaaagttggg ggaaaaggct tcgtggactg atattgaact
     7381 ttattcttac atggaacaac ttcatcgtaa ctattctgtt aacagaaatt caaggaattg
     7441 ttgtattcaa tttacttatt tgcctagata tgtgagaaat acagaatggt tcgatgaaac
     7501 agtctggata ccatttgaga gaatagaatt gcctgttcct ttggcatatc atgaagtgtt
     7561 gaagcatgaa tatggtgatt atatgaaacc gatcaagggg gcgagtcttc atggtaattt
     7621 ggtggtagat gtagatgaat cttacgagaa atatctttca ggtctgaaga tgtcttttct
     7681 aaaagctaca tatttgttta taaagtcagg gggcgggatg gtgcttcgtg tatttggttt
     7741 gagaaaaaag taaatttagg atagcggcga ctacgttatg aaagataaag ctgtcaacgg
     7801 tgttttttgg acttcggtgg aaagaattgg tagtcaggtg cttagtcttc ttgtaggaat
     7861 agcagttgcg aggattctat ctccagaaga ttatggtata ataggaatga ctgccatttt
     7921 cttagcagta gcttctactc ttcttgacag cggatttggt agcgcactaa tacaaaatca
     7981 aaatagaaca gaaactgatt attctacttg cttttatttt aatatagttg taggtctgtt
     8041 ttggtatgta gtattgtttt tagcagctcc gctaatagca gacttttatc gtacgccatt
     8101 gctggaatcg gtttgcagag ttctaggttt ggtttttgta ttcaattcac ttacaatttc
     8161 gcagacggca cggcttaccg tagaatttag atttcgggaa ctgtgtttcg ttacattagg
     8221 tacgcagttg ttaacgggaa ttgttggttt cattatggca tttaaaggtt atggagtatg
     8281 ggcgttggtg tttcagcaag taggcgcagc ttttttaaga gtatgtctga tagaatggat
     8341 tacacattgg aaaccgttac ccttgttttc caagattgca ttttgtagaa tgttttcatt
     8401 tggttctaaa atactatgtt caggcattat aaatactgtt tatgacaata tctatacatt
     8461 agtgataggg cgtgtctttt cacctgtaga agttggattc tataatagag gaaatcagtt
     8521 tgcacaatta ccatctcaaa gtttgctatc tgttgttatg aaagtcgttt atccattgat
     8581 ggcagaagtg caagatgatt cggaaaaact ttgtagagct tatcagaaat ttttgcgtat
     8641 ttcggttttc attctttatc ctattcttat tgggttaata gtcttagcag agtcttttat
     8701 ttatgtattg ctaggcgata aatggttgcc ttgtgttccc ttgatgcaaa tattatgttt
     8761 tagctacttg tttgacccac ttacacatat aaatcttaat attttgtatg taagaggacg
     8821 gactgattta gtacttaaac tagaacttat aaagaaaccg atagcattga ttattttgtt
     8881 tggaatgcta ccattcgggt tatggtggct gtgtgcagga cgtgctttgt acagttttat
     8941 agcgtactgc tttaattgtt tttatactgg aaagtttatt agatttggtt ttaggcaaca
     9001 gatgtactat agtgtacctg tgattgtaaa atctgctttg atggggatta tttgttggag
     9061 aacagcatta ggctttgaag aaccatggtt aaagttgatg gtaggatttt tggcaggatt
     9121 gctttcttat ataggactga attttataag tcatgatgaa agtttttttg atataaaagg
     9181 gataatattg aaaaatggga aatgataaat aatataataa tgaacaaaat attatctgta
     9241 gttattcctt cgtataatat ggaggagtat ttgtaccgaa atgtgagtag catgatgatt
     9301 ggggaaatat tagatgacct tgaaatcatt attgttaatg acggaagtaa ggatagaacg
     9361 tctgaaatag cacatgaact tcaaagaaaa gcttctcaaa gtattgttgt tattgataag
     9421 gaaaacggtc attatggttc atgtgtaaat gcagcgttga agatagcaac aggcaaatat
     9481 tttcgaattt tggatgcgga tgactggatg gatagcggtg aatttgtaaa atttgtaaat
     9541 atattgaagt gtattgatgt agactgtatc tatacacctt ttgcgaatgt tttttttaat
     9601 aaaaatagaa aggaatattg tattgctgat aatgcagtgt ggaataaaaa gatagatctg
     9661 agtcatgtct cattgccccc ttcttatttt cacatgcact cattgactta tcggactcat
     9721 ttgttacata aaataagttt tgtgcaggaa gaaaagattt gttatacgga ttcagagtat
     9781 gttttttatc ctttgtctca tgcaaaatcg ttatactgta ttaatgtttg cccttatcag
     9841 tattatatag gtcgcgaagg acaatctgta tcattggatt ctttgagtaa aaactatgct
     9901 cattttgaga aagtattggc aaatatcagt ttttataagc ctatggaatt gttaccgaca
     9961 tattcatcac ttagaaaata ttatattgtg acgctgctac gttatatgct tgatattcat
    10021 cttttttcac agaaaaagga tgttcagaga gacaagctat taagagacaa aataagggct
    10081 tttggtgatg acgttaacat tagtgaacaa attaaagaca tcaatcttaa ggggttgcat
    10141 tatattaatt ggtggttgga taatacaggt gttgataaat taaaacttaa aattcttgtc
    10201 ttattaaaaa aagtacaaca tacaatagtt aattgaaatg cctaaaatta gcgtaataat
    10261 accggtgtat aaagtagaac aatttataga aaggtgtgca attagtcttt tcgaacaaac
    10321 tttagacgat attgaatatc ttttcataga tgattgttca cctgataatt cagtggagat
    10381 tattaaaaat gttttgatgc gatatgaaac aagaaaagat tcggttcgta ttatatctat
    10441 gcaaaagaat tgtggacaag ctgctgtgcg tagatatggc aatagtatag ctcgtggtga
    10501 ttatataatt cattgtgacg gagacgattg ggtggatatt aatatgtact acaaaatgta
    10561 cgagtgtgct gtcaataata agttagatat tgtcaggtgt aaattttgta gaacagatgg
    10621 aaagttaatg aaagaatgta ttaatatccc aagtaatata tattgtgatg caaaaaaaat
    10681 gatttcctac ttgttaaggt tatctgattt atcttcaact tgcgataaat tggtaagacg
    10741 ggaactttat caatcagtag attttatata tcctgttgat aatatgtgtg aagatttcgc
    10801 aattgtaact caattgtttt gtcgtactga taaaattgga tatatagatg aagttctcta
    10861 tttttattat caaaataaat tttcaataag tcatatattg gataatactc atatagataa
    10921 taaggcacaa caaataagca ataatgtaaa actgatagga aaaattttga aaacaaaata
    10981 tccaggtgga attttcgata aagaaattga agtaattaaa ttgatggcaa aaaatgccta
    11041 tagacctatt ataagaagag aagggtatta tgaaaagtgg aaaacattat ataaggaaat
    11101 aaattcgaaa atatttttca atgaatatat aacaataaaa gaaaaattgt catttatagc
    11161 ttgctatatc gggatatatc ctttgttgac tgggcgtaaa tagtaaatat gggaaatata
    11221 gaaaattgta tatatttaat tactttgttt ttgtttgaga tattattatt tctttatgta
    11281 tggcagaagt ttgatagatc tattttttct ccatcaatat atactatcgg tgttttagga
    11341 tttggaacat tgctgaatat ttggtgtgtt gattattggg atattagttt tcatccacgt
    11401 acatttggaa ttatagcttt aggattatgc atgatggtta ttgctgaaaa aaatgcttat
    11461 ataaaaagac gtaatgatag tgaatataag atgttttata tttctttacc tcctatgtta
    11521 gttatctctg tggctgcata ttgcattgta gcaacatttt tgtattttaa tgaaatacgt
    11581 agattggggt tagcgcaatc tttggcggtt tcagaagcga taggtaatat aaaggaaaat
    11641 tttgaggaat ttgaagaatt atttaaccca tttattcggc aaggatataa aatagtt
//
