LOCUS       c00023_gnlPro..        24638 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KIPOLNCM_23.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 12:22:14
            Original ID  :: gnl|Prokka|KIPOLNCM_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 288178
            Orig. end    :: 312816
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24638
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[298178:302816]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14638
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24638
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24638
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(1044..3776)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_220"
                     /sec_met_domain="Peripla_BP_1 (E-value: 8.6e-07, bitscore:
                     22.6, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPALTYYALLALFLAFCFSCKTDSEKKKYVIGVSQCTLEGSWRK
                     SMLLDMKVQASEYPGVSLLVEDAADSSLLQVEQIRSLIKRKVDLLIISANESEPVTPIA
                     IEAYRAGIPTILVDRKISSDEYTTYIGGNNYEIGRQAGFFVNRQVKEKYPTVLEVWGLS
                     GSSPAQDRHRGFMEVLNSRIKVKEIFGKWKPETVEKEIAEMDSLEEVDVVFAHNDVMAM
                     AARRAIERMHPGLADRICFVGIDAVSGRGSGLEAVMHGELAASVLYPTGGSLAIRVAMQ
                     ILNGEDVSRQYLLSSALIDKNNAGTLFIQSEQVVDYQHQIELQRENLESMLSKYTFLQN
                     SVGIILLLMGMLLLSALYVIHVNRAVKRKNRELKRTNLQVQQQKEELAEANRYIEKSTA
                     QKLQFFTNITHEIKTPLTLILGPLGKLSKEAPEGSSLADDIRIIRKNAERLKRVVDQLL
                     DFRKVESNKMNMRVGEVDLVAFVAEVKSYFDTMAATKQIHFTFEHDCPSVNIWVDRDKM
                     EKILANLLSNAFKFTLDGGTVTIHLKDKGDQVELSVEDNGKGIPSENIASVFDRFFTGD
                     QNYVTGTGIGLHLTREFVHMHKGTIRVESVPHKSTVFTVILLKGKSHFDESCTFDLSVT
                     ELSSGVADLNTDELQEVLNRTYNYTVLVVEDDLDIQSYLQAELKQNFRVLVADNGVKAL
                     EVLMSEEVSMVISDVMMPEMNGFDLCRKIKSDIVLSHLPVMLLTALSDDKQQMYGAASG
                     ADAYIQKPFNIEVVKLRIIKLLEDRVRLREAYARDASSPAVSVKEEKAGSMDDLFMNRF
                     LKLIEESYADPDFSIEKGSEKLGLSRVHLYRKVKELAGVTPTDFLRNYRLKKAAALLRR
                     KAGNVNEVAYATGFGSPAYFSKCFKAVYNITPTEYLEKE"
     CDS             3873..4340
                     /locus_tag="ctg23_221"
                     /transl_table=11
                     /translation="MKIINEALLDETTGRAKQSPRLRMNYNFHEHLDDPVNRLLNALEP
                     GTYLRPHRHLNPKKDEIFLLLRGRIAVFLFDNKGEITKTQILDPKEGVYGAEIKAGTWH
                     GLLVLESGSVIYEIKEGPFAPLAPENFAPWSPAPEDTKGVAKYMELLGKAI"
     CDS             complement(4558..6387)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_222"
                     /sec_met_domain="Peptidase_U32 (E-value: 4.9e-73, bitscore:
                     239.1, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTKSRPIELLSPAKDLNCGIEAINHGADAVYIGAPKFGARSAVG
                     NSLEDIRELCEYAHLYEARIYVTLNTILKEEELEEAERMIWDLWRVGTDALIIQDMGIT
                     RLNLPPIPLHASTQTDNRTPEKVRFLEAAGFTQVVLARELSLNEIRRISEATTVPLEVF
                     VHGALCVSYSGQCYLSAALSGRSANRGECAQYCRLPYTMVDATGTEIVTHKHLLSLKDM
                     NRSDQLEALLDAGVSSLKIEGRLKDAGYVKNITAYYRKKLDAVLSRRPEYRRASAGRST
                     YTFEPVAEKSFNRGFTPFLLEGRTADITAFNTPKSLGEPVGTVKEIKGNSFTVAGLKQL
                     NNGDGLVFFNRKGELEGFRVNRVEANRVFPLDMPQLAPKTPLYRNFDQAFDKLLAKPSA
                     ERKLSVEIEFLDNPFGFTLCMEDETGARIMLTEPFAKELARREQQDNIRTQLSRLGNTP
                     FEASKVVVGLFENWFVPSSLLADMRRRGVEKLLEARRARYPRETVKRVQPSVSIPFPER
                     QLTYLGNVANGKARSFYQDHGVEQIDPAFELSPRKDVPLMFTKHCLRYSMGWCPTYQKD
                     KSPYKEPYYLLYKDTRLRLQFDCKHCQMLVFES"
     CDS             complement(6410..7342)
                     /locus_tag="ctg23_223"
                     /transl_table=11
                     /translation="MPLNLQKNLPAVELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMP
                     LKITTETDLVRLLSNTPLQVELDFMKIKGHTPKNTPIEHMKEFYKDFDEMQDDFYDGMI
                     ITGAPVEQMPFEEVNYWEEVTEIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDLPAK
                     MFGVFRHTLREPYVPIFRGFDDEFYVPHSRHTEIRREDVMKVPDLTLLSESEESGVYMA
                     MARGGREFFITGHSEYSPYTLNDEYMRDVNKGLPIAVPRNYYRNNNPALGPVVRWRGHA
                     NLLFTNWLNYYVYQETPFRIEDISKLGDL"
     CDS             7451..9856
                     /locus_tag="ctg23_224"
                     /transl_table=11
                     /translation="MKIRAIATLLFILFSISAFGQGRAKISGYIRDADGNPLDLVNIRV
                     KNTLNGTMSNEKGHYSLSVATGDSVTLIYSCLGYNKAERILPQVTKDMRLNVQMNYTSL
                     ELGEVVATAIRKQTTTLETLNADRVKLLPDPAGGSIESLVVTFAGVTSNNELSSQYSVR
                     GGSYDENIVYVNGLEVFRPLLIRSGQQEGLSFINPDMTEAVNFSAGGFEARYGDKMSSV
                     LDITYKKPKGFEGSASASLLGANAYVGSSSGKFTQVTGFRYKTGRSLLKTTDTDAEYDP
                     NFIDLQTYITYQLAPKWEINFLGNLAINNYKFIPHTRETSFGTATNAKKFKVFMSGQER
                     DKFETLFGALTLKHNLNDNTELGLQASAFTSKEEEGYDIAGDYWLGDAAEEGGGEIQNL
                     SIARYNEHARNRLHSNIMNVGHYGVARIKNNTLKWGATVQLEKINDKISEWEKRDSAGY
                     SLPQGGGNVNVIANLFSDNKLESTRISGYLQDVFKFRTKQGLFTLVGGVRGSYWSYNRE
                     FIFSPRASIGFIPNFDQNLTFRLASGLYYQSPFYKELRTTVQDEYGNSIIQLNKNLKSQ
                     RSIHVIAGGDYTFRASGRNFKVSADMYYKKLDNLNPYTVDNVKIRYYGENCAQGHAMGL
                     DVKFFGEFVPGTDSWISFSLMKAEQSIRGSEYVPMPNSQGYNVSLFFQDYFPGYKRVKL
                     NLKGVLSGGLPVTAPRTGYEDGYFRTPTYKRVDLGFSYQLAGGTDAIMDRGFFRNLKNI
                     WLGLDIFNLFDIKNTSSYYWITNIDNHQYAIPNYLTGRQLNIRLIVDF"
     CDS             10001..10408
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_225"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.7e-26, bitscore:
                     86.7, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEEVLGLKCYNIEEVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALDEAESKGIKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGK"
     CDS             10521..12074
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_226"
                     /sec_met_domain="CT_Btheta (E-value: 3.1e-291, bitscore:
                     960.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALRETARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIYAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLISFLPQNNLEETPLIECKDPIDRLDDNLNDIIPDNPN
                     QAYDMYEVIGTIIDNGEFLEVHADYAKNIIVGFARFNGQTVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAASEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             12096..12983
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_227"
                     /sec_met_domain="OAD_gamma (E-value: 2.2e-11, bitscore:
                     38.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINKKIGVLLLFALLVSFGAKAQRATSMRINEVLVINEDNFVDDY
                     GKRHAWIELFNNSAGSVNIAGCYLTNDKSNPKKYPIPKGDVLTVIPPRQHTLFWADGEP
                     DRGTFHVNFTLDPSKENYIALYDADGKTLIDEIVIPASQKADVSYGRTLDGQGEWTALT
                     KVTPSTNNVTLDSNEKIENFKENDSWGIGMTLTAMAVVFSGLFLLFIIFKQIGKLSIAA
                     SKRNAQKAAGAAVIADNAGQESGEIFAAIGAALYEMSDDNHDIEHTVLTIRKVQRSYSP
                     WSSKIYGLREVPKK"
     CDS             13006..13437
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.5; E-value:
                     9.6e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_228"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.1e-20, bitscore:
                     65.5, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHISSVVDDIAEVEVNGTPYQVKMEKPAKKQ
                     MVTLKRPAQAPTTASGEPVISRPAASTTKGAVKSPLPGVILQVNCKVGDTVKRGQNLLV
                     LEAMKMENNINADRDGKIIEIKVNKGDSVLEGADLVVIG"
     CDS             13442..14638
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_229"
                     /sec_met_domain="OAD_beta (E-value: 3.1e-152, bitscore:
                     500.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGSVLLQAAGTAHESFLQFLGENLELFLTYTGVYNATPGHLIMI
                     LVGLLFIFLAIKYEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTS
                     GWYPPLIFLGIGAMTDFSALISNPKLMLIGAAAQFGIFGAYIIALQMGFEPNQAGAIGI
                     IGGADGPTAIFLSSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTQKERLIRMKPP
                     RAVSSTEKIVFPIVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDT
                     ITILLGITVGASTQATQFLTLNSIKIFGLGALSFVIATCAGILFVKFFNLFLKEGNKIN
                     PLIGNSGVSAVPDSARISQNVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(14831..14983)
                     /locus_tag="ctg23_230"
                     /transl_table=11
                     /translation="MDMRRKNTNVLLVFGVVIAIILLMIWLFLGTTLEQEANPETDPMT
                     VEQNI"
     CDS             complement(15259..17307)
                     /locus_tag="ctg23_231"
                     /transl_table=11
                     /translation="MHSRDMEYIVGLLKNGKDAEAILSVRRKLNMAFLARTTDLSGKLP
                     VLAFGSTFKKNGDGIQLRRYNGYVLLEVNGLESQSEAEAVRREAAALPQTLLAFVGLSG
                     RSVKIVVPFVLPDGSLPKKEEQARMFHAAAYQLAVRHYQPQLGSIISLKEPFLSRGCRM
                     SVDPDAYYNPDAVAIRIEQPLQMPDGGDLKIVPSPVRDPLEMMAPGADRNGQIATLFSV
                     ILMEMTRRFSESPEDDIQLLFIDLAQACCRLGIPEEEAVGWTLRYEALKKYKIDVRMAF
                     RTAYTLENVSNRAEPLSSVPPSMSLVLRLDEFMNRRYFFRTNEMSGGVEYLDRSMIQFV
                     YKPYTTKVRNSICLEAQQEGLNVWDKDIDRYVNSDRVPIYHPIDHFLGNLPAWDGKERI
                     RALAGRVPCDNPIWGDLFYRWFLSMVAHWMELDSEHRNSTTPLLVGGQGCGKSTFCLNL
                     LPPVLRPYYTDSIDFGNRRGAELALHRYALINIDEFDSVKSSHQSFLKHILQKAVVNTR
                     LPYQSASRNLRRYATFIATSNNYDLLTDPTGSRRFICVEVKGRIDYAQPIDYDQLYAEA
                     KELLRRGERFWFTPEEEALITENNRDFQQQPAEEQLFLRYFKIAEDIEEAKPLLASEIL
                     DMIAEKQPGFNITKTMILNFGKLLKRNSVPNKRTMRGTCYYVEEVDG"
     CDS             complement(17349..17735)
                     /locus_tag="ctg23_232"
                     /transl_table=11
                     /translation="MAHYYVVRQKLDKTGAEDKVRYYGVPVTCGRVSTKKLADLVADRC
                     SLSRGDVFASVCEIGGMILELLKDGYSVELDGLGDFYLSAGSEGFEDPKKCTPHRVKAR
                     RVCFRMAPCVRKSMKFVKFERNPW"
     CDS             18109..18381
                     /locus_tag="ctg23_233"
                     /transl_table=11
                     /translation="MYIIGGCLQQLIYIACRRKTYMDGNPKLTHRPVSMFDIVAIKHKK
                     QDDFAYLSSFPIDRTYIKISTNVPFRHSTQLHHRAKSTLFFATVA"
     CDS             complement(18339..19058)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_234"
                     /sec_met_domain="Peptidase_M22 (E-value: 3e-23, bitscore:
                     76.9, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSCILNIETSTSVCSVALSMDGEVLFAKASFDGPSHAALLGVFVE
                     EALSVLKKKGKKALDAVAVSSGPGSYTGLRIGVSVAKGLCFGFGIPLIGIHTLDIMAAT
                     VNSKGDSQIVSITDNCLYCAMLDARRMEVYAAIYDASLKPVRETKADIVEVGTYASYLE
                     KGKVCFFGNGASKCKSVITSPNAIFIEDIHPLAVNMIPLSEQAFAAGKFEDTAYFEPFY
                     LKEFQATVAKNKVLLAR"
     CDS             19294..20154
                     /locus_tag="ctg23_235"
                     /transl_table=11
                     /translation="MTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKEKEMQI
                     RSLLLQSLERGKVEFNIFVEYIGKDTPTQINLAAVENYYNQIKDIADRLNIGLPADWFQ
                     TLLRMPDVIKTEAQEVNEEEWNVVEKAIKEAIGHLCDFRIQEGAMLQKLFEQKIANISR
                     LLSEVEQYEKERIEKIKARIMDNLEKIAGQDYDKNRFEQEMIYYIEKLDVNEEKNRLDN
                     HLKYYISTMESGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKLVVQMKDELEQIKEQ
                     VLNVL"
     CDS             20164..20733
                     /locus_tag="ctg23_236"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINFLLKQNLNLHFSISATSRAPRGTE
                     KDGVEYYFLTPDEFRARIAAGDFLEYEEVYTDKYYGTLKSEVERRLMSGDNVIFDVDVV
                     GGCNIKKFYGDRALSVFIQPPSIEDLRSRLEGRGTDAPEVIESRIAKAEFELGFADKFD
                     VIVVNDKLEVAEKEALKVIKEFLKKA"
     CDS             20730..20903
                     /locus_tag="ctg23_237"
                     /transl_table=11
                     /translation="MNGKKLSKKWLYTFIGIAFVALATCTAALYYKEYIIATGTGLVFG
                     AQVINIIKWKRD"
     CDS             20888..21499
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_238"
                     /sec_met_domain="CTP_transf_like (E-value: 4.4e-24,
                     bitscore: 79.4, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VETGLKENTASKRKTGIYSGSFNPVHIGHLALANWLCEFTELDEL
                     WFLITPHNPLKEKEELMDDRLRYELVKKSIAGYPKFHASDFEFSLPQPTYTINTLRTLE
                     ASYPDREFYFIMGADNWKYITRWVEYEAIISNYPIFIYPRKGFNVEIPAQYPHIKKVDA
                     PLVEISSTFIREAFKTGKDVRFFLPEAIRNLPFPLQNNTF"
     CDS             21590..23320
                     /locus_tag="ctg23_239"
                     /transl_table=11
                     /translation="MNLLELSEQEIIRRNSMEQLRQMGIEPYPAAEYVTNAFSKEIKEN
                     FKDDAEPRPVSIAGRIMSRRIMGKASFMELQDSEGRIQVYISRDDICPEENKDLYNIVF
                     KKLLDIGDFVGIKGFVFRTQMGEISVHAQEITVLSKSLKPLPVVKYKDGVAYDGFNDPE
                     LRYRQRYVDLVVNDGVKDIFMKRAAVIKTMRTALDEAGYTEVETPILQSIPGGASARPF
                     ITHHNSLDIDLYLRIATELYLKRLIVGGFEGVYEIGKNFRNEGMDRTHNPEFTCMELYV
                     QYKDYNWMMSFTEQLLERICIAVNGTCESVVDGKTINFKAPYRRLPILDAIKEKTGYDL
                     NGKSEDEIRTICKDLNLEIDETMGKGKLIDEIFGEFCEGTFIQPTFIIDYPVEMSPLTK
                     MHRSKPGLTERFELMINGKEVANAYSELNDPIDQEERFKEQLRLSEKGDDEAMFIDQDF
                     LRALQFGMPPTSGIGIGIDRLVMLMTGQTTIQEVLLFPQMRPEKTVKKDTADKYVALGI
                     DEAWVPALHKAGYLTTDTLVDANPNKLRQELCEMNKKYKLELQNPTAEEVEAWIAGAAK
                     "
     CDS             23358..24326
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_240"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 4.4e-30,
                     bitscore: 98.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGGSWATALAKIVLSTQDSINWYMRRPDQVEEFLLLGHNPSYLS
                     AVKFDTDKIKFYTDINKVIKDSDTLIFATPSPFLKQHLMKVTTSMQDKFIISAIKGIVP
                     DENMLVADYFAEYYNVPIDNIAVIGGPCHAEEIALERLSYITLACPNIENARAFSSVFK
                     NQYLNNSCCKDVTGIEYASVLKNVYAIVAGICHGMKYGDNFLAVFICNAIEEMRNFLNA
                     VHGLERDVTDSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKIAQLEMEMIAEGYYGTK
                     CIREINEKYKVNMPILDTLYSILYEKKSPTTAIRQLTETFK"
ORIGIN
        1 tgccggccat gccccctctt tcgtacagac ataagcagct gtgcggacgg caaattcatg
       61 cgcttccctt agcgaagccc ctttcagcaa cgaaatgacc aatgctccgg agaaagcatc
      121 acctgctcca accgtatccg ccacctgcac ttccggggtt tgcaaagtcg attcttcatt
      181 agcggtatat atcgtactat aagctcctcc gaccgtcaga accaccaagc ggagattata
      241 gtgttctata aaccaatgag ccacctcctt gtccgttcct tccaaatgaa acatatcccg
      301 caggacgacc aactccccgt cattcacctt caacatattt gctagataaa gcgactcttc
      361 gatcaactct ttcgtataat aatgctgacg caaattgatg tcaaaacaac gataagcatc
      421 gtccggggca aaagaaagaa tcgcctgtat cgtctctctc gactgtgcgg aacgctgtcc
      481 taacgtaccg aagcaaatgg catccgcccg ttcggccaaa tcaatcgcat ttgacgtcgg
      541 agaaagatga tcccaagcta cacgttcatt aataatatag tcagggacac catcctgcag
      601 agtaacctgt accgttccgg tcggataagg gactttctcg atcagatacc ggatcgaatt
      661 attatccagt tcttcgagga tttcgcgccc cagcccatcg tctcccacgg cgctgatagc
      721 atatccttcc gcccccaacc gcgacgcatg gtagacaaaa ttgataggag caccacctgc
      781 tttctttcct gttggcaaca tgtcccacag gagttctcct atgcctacta cgaccggttt
      841 cttattgttg ctttgcattg tttcattata gtttatttga caaggataat ttattatcta
      901 cgatgcaaag atagagacag gtagcagatg cgacgataac taatgctaca agattgataa
      961 cacttgttac attatactct tattttcgag ttacatgcac aagtgttaca caaatgtaac
     1021 gagcgttatc aaagagaaga atattattcc ttttccagat actccgtcgg agtaatattg
     1081 taaacggctt taaaacattt cgagaaataa gcaggcgaac cgaagcccgt cgcataagcc
     1141 acctcattca cattcccggc tttccgtcgg agtagagcag cagctttctt caaacgatag
     1201 ttacgcagga aatcggtcgg tgtcactccg gcaagctcct tcaccttccg gtaaagatgc
     1261 acacgcgaca agcccaattt ttcactacct ttctcaatac tgaaatccgg atcggcatag
     1321 gactcttcga tcagtttcaa gaaacgattc ataaaaagat cgtccatgct tcccgctttt
     1381 tcctccttca cggaaacagc aggcgaagaa gcatcgcgag cataagcctc acgcaaccgg
     1441 acacggtcct ccagcagctt gatgatacgc agtttcacga cttctatgtt aaaaggtttc
     1501 tggatatacg cgtccgcacc actggcagcc ccgtacatct gttgcttgtc gtcggacaaa
     1561 gcagtcaaca gcataaccgg aagatgactc aggacaatat ccgacttgat cttacgacaa
     1621 agatcgaaac cgttcatttc cggcatcatc acatcgctga taaccatcga aacctcttcg
     1681 ctcatcagca cctccaaagc cttcacgccg ttatcggcaa ccaacacacg gaagttctgt
     1741 tttaattccg cctgcaagta actctgtata tcaagatcat cttctacgac cagaacagta
     1801 taattgtagg tacggttcaa aacctcctgc aattcatccg tgttcaagtc ggcgacacca
     1861 ctggaaagct cggttacgga aagatcgaat gtacaagatt cgtcaaaatg agatttacct
     1921 ttcaagagga tgaccgtaaa gacagtactc ttatgcggaa cactctccac ccggatcgtg
     1981 cctttgtgca tgtggacgaa ctcacgcgtc aagtgcaggc cgatccccgt tcccgtcaca
     2041 tagttctggt caccggtaaa gaaacggtca aagacggaag caatattttc cgacggaata
     2101 cctttgccat tatcttcgac agaaagctcg acctgatctc ctttatcttt cagatggatc
     2161 gtgaccgtac ctccgtccag cgtgaacttg aatgcgttgg acaaaagatt ggccagaatc
     2221 ttctccatct tatccctgtc tacccatata ttaacagaag ggcagtcatg ctcaaacgtg
     2281 aaatgtatct gcttggtggc agccatcgta tcgaaataag atttcacttc tgccacaaaa
     2341 gcaactaaat ctacctctcc gacccgcata ttcatcttat tgctctctac ctttcgaaaa
     2401 tcaagtaact ggtccacgac tctcttcaac ctttccgcat ttttccgaat gatacggata
     2461 tcgtctgcca atgaagaacc ttccggagcc tctttcgaca gcttgccgag cggaccgagg
     2521 atcaacgtca acggcgtctt gatctcgtgt gtgatattgg taaagaattg cagtttctga
     2581 gccgtcgact tctcaatata acggtttgcc tcagccaatt cttctttttg ctgttgtacc
     2641 tgcaagttcg tacgtttcag ctcgcggttc ttccgcttca ccgcccggtt cacatggatc
     2701 acgtacaagg cggacaaaag caacatcccc atcagcaaaa ggataatgcc gacggagttt
     2761 tggaggaacg tgtatttgga aagcatactc tccaaattct cccgttgcaa ctcgatctgg
     2821 tgctgatagt cgaccacctg ttcggactgg ataaacagcg ttccggcatt gttcttatcg
     2881 atcaaggcag aagagagcaa atattgccga gacacatctt ctccgttcaa tatctgcatg
     2941 gctacacgga tagcaaggct cccacccgtc ggatacaaga ccgaagcggc caactctccg
     3001 tgcatgacgg cttccagccc cgatccccgt cccgaaacgg catcgatccc cacaaaacaa
     3061 atcctgtccg ccaatccggg atgcatcctt tcgattgccc tgcgggcagc cattgccatc
     3121 acatcattat gggcaaacac aacatccacc tcctccagcg aatccatttc cgctatctcc
     3181 ttctccaccg tttccggctt ccatttcccg aatatttcct tcaccttgat gcgggagttc
     3241 aaaacctcca taaaaccgcg atggcgatcc tgcgccggag aagaaccgga caagccccat
     3301 acttccaata cggtaggata tttctctttc acctgtcggt tcacgaaaaa gccggcctgg
     3361 cgaccgatct cgtaattgtt accaccgata taagtcgtat attcgtccga actgatcttc
     3421 cggtctacca ggatagtcgg aatgccggca cggtaggcct caatcgcaat aggagtgaca
     3481 ggttccgatt cattggcgga gataatcaat agatcgacct tacgttttat caggctgcgt
     3541 atctgctcca cctgcaacag actactgtcc gccgcatcct cgactaacag ggagacgccc
     3601 ggatattcgg aggcctgcac cttcatatcc agcaacatcg atttacgcca agaaccttca
     3661 agcgtacact gcgagacgcc aataacatac tttttcttct ccgaatctgt tttacaggaa
     3721 aaacagaatg ccagaaataa ggccagtaga gcgtaataag ttagagcagg tttcattctg
     3781 ttttatttac aggtttctgc aaatgtacgg agaaatggca taccagccaa tatttatttt
     3841 gtacattcgt cctccagtaa tcaattattc gcatgaagat cataaacgaa gctttattgg
     3901 atgaaacgac cgggcgtgcc aaacagtcac cccgactacg catgaactac aactttcatg
     3961 agcatttgga cgatcccgtc aaccgcttgc tcaatgccct tgaaccggga acctacctcc
     4021 gcccacaccg ccatctgaac cctaaaaaag atgaaatatt cctcctgctg cgaggtcgca
     4081 ttgctgtatt cctctttgac aacaaagggg aaatcaccaa aacacaaata ctcgatccga
     4141 aagaaggtgt ctacggcgcc gaaataaagg cgggaacatg gcacgggctg ttagttctag
     4201 aatccggctc tgtcatatat gaaatcaagg aagggccgtt cgctccgctc gctccggaaa
     4261 atttcgcacc ctggagtccg gctccagaag acacgaaagg ggtggcaaaa tatatggagt
     4321 tattaggaaa ggctatataa ccttgcacta ccttcccgtt ccccttaaag aaaactttat
     4381 tttcataggg atgaaacttc tttttcatcc ccatgaaact atcattccat ccctatgaaa
     4441 ctgttatcac atacctatcg gctcctttat tgctggaata cttttgtcaa acggatcatg
     4501 gcttctttca ccggacagtc attcttatcc gtcctgacaa tagcgttctc ataattttca
     4561 actttcaaat accaacatct gacaatgctt gcagtcgaac tgcaaccgga ggcgcgtatc
     4621 tttataaagc agataatacg gttccttgta gggagacttg tctttctgat aagtaggaca
     4681 ccaccccatg ctgtagcgca ggcagtgttt ggtaaacatc aacggaacat ctttccgggg
     4741 agacagttca aatgccgggt cgatctgttc caccccgtga tcctggtaga acgaacgggc
     4801 tttcccgttg gcaacattcc ccaaataagt aagttggcgt tcggggaaag gtatcgacac
     4861 ggacggctgc acacgtttca ctgtctcacg aggatagcgg gcacggcgtg cttccagcaa
     4921 cttctccact cctctacggc gcatatcggc aagcagagaa gagggaacga accagttttc
     4981 aaacaaaccg accaccacct tcgatgcctc gaaaggcgta ttccccaacc tggatagctg
     5041 tgtccgtata ttatcctgct gttcacgacg cgccagctct tttgcaaacg gctcggtcag
     5101 catgatccgt gctcccgtct catcctccat acaaagcgta aaaccgaagg gattgtccaa
     5161 gaactcgatc tccacggaca gcttacgttc ggctgaaggc ttggcgagca gtttatcaaa
     5221 cgcctggtcg aaattgcggt aaagaggagt cttgggggca agctgcggca tatccagcgg
     5281 aaacacccgg tttgcctcca cccggtttac acgaaaacct tccaattcgc ctttcctatt
     5341 gaagaaaaca agcccgtctc cgttgttcaa ttgctttaag ccggccacgg taaaggaatt
     5401 acctttgatc tccttgactg ttccgacagg ttcgcccaac gacttaggtg tattaaaagc
     5461 ggtaatatcc gccgtccgtc cctccaaaag gaacggggtg aacccacggt taaaactctt
     5521 ttcagctacc ggctcgaacg tataagtgct tcgtccagca gaagcacgac gatattccgg
     5581 acggcgggac aggactgcat ctaacttctt ccgataataa gccgtgatat tcttgacata
     5641 gccggcatct ttcaaccgcc cttcgatctt gagggaagaa acacctgcat ccaacagggc
     5701 ttccagctgg tcggagcggt tcatgtcctt gagcgaaagc aagtgtttat gggtgacgat
     5761 ctccgtccct gtcgcatcga ccatcgtata gggcaggcgg caatattggg cgcattctcc
     5821 gcggttagca ctacgtccac tcaaagcggc gctcagataa cattgcccgc tatagctgac
     5881 acagagggcg ccatgcacga atacttccag cggaacggta gtcgcttccg atatccggcg
     5941 aatctcgttc agcgacaatt cacgtgccag aaccacctgt gtaaagcctg cggcttcgag
     6001 gaaacgaacc ttttccggtg tgcggttgtc cgtctgcgtg ctggcgtgaa gcggaatagg
     6061 aggcaggttc agccgggtaa tccccatatc ctgaatgatc agggcatccg tcccgacacg
     6121 ccagagatcc cagatcatcc gttcggcttc ttccaactcc tcttctttca ggatcgtgtt
     6181 gagcgtaaca tagatacggg cttcatacag atgcgcatac tcgcaaagct cacgtatatc
     6241 ttccaaagag ttgccgacag cagaacgcgc accgaacttg ggcgcaccga tatagacggc
     6301 atcggcaccg tgattaatcg cttcaatccc gcaattgagg tctttagccg gagagagaag
     6361 ttctatagga cgggattttg tttgcatgct attatttctt atttcttgat tacaaatcac
     6421 ccaacttgct gatatcctcg atacggaacg gggtttcctg atagacataa tagttcagcc
     6481 agttggtgaa cagaagattg gcatgaccac gccagcggac caccggaccg agggctggat
     6541 tgttattacg gtaatagtta cggggaacgg caataggcaa tcccttgttc acgtcgcgca
     6601 tatactcgtc attcagcgtg taaggcgagt attcggaatg cccggtgata aaaaactcgc
     6661 gtcctccgcg cgccatcgcc atatagacac cagactcttc gctttcggac aagagcgtca
     6721 aatcgggaac tttcatcaca tcctcgcggc gtatctccgt atgccggctg tgcggcacat
     6781 agaactcgtc gtcgaagcct cggaagatcg gcacataggg ctcgcgcaac gtatggcgga
     6841 acacgccgaa catcttggct ggcagatcat atttggggac accataaaaa tggtacaacc
     6901 cggcttgcgc cgcccagcat atatataagg tagaagtcac atgcgtacgc gcccaatcga
     6961 atatctcggt cacttcctcc caatagttca cttcctcgaa aggcatctgc tctaccgggg
     7021 cacctgtgat aatcatgccg tcgtaaaaat catcctgcat ctcgtcaaag tctttataga
     7081 attccttcat atgctcgatc ggcgtgttct tgggagtatg gccttttatc ttcataaagt
     7141 cgagctccac ttgcaagggg gtattgctca ggaggcgaac aaggtctgtc tccgtcgtga
     7201 tcttcagtgg catcaagttc agcacaacta cacgtagcgg acgaatgtcc tgctcagacg
     7261 cacgcaacga gtccatcaca aagatgtgct ctttcttcaa cagctcaaca gctggcaagt
     7321 tcttctgtag gtttaaaggc atcttctttc cttaattatt tatacaaggc acaaagatag
     7381 tgagaaattg cctttcgttg aaaataaatc gttgtttccc gcgtttgtag atttaataat
     7441 tagatggaat atgaagattc gtgcaatagc tacactacta tttatattat tttcgataag
     7501 tgctttcggg cagggacgtg ccaaaatcag cggttatatc cgcgacgcgg atggtaatcc
     7561 gctggacttg gtcaatatcc gggtcaagaa cacgttaaac gggacgatga gtaatgaaaa
     7621 aggccactac tcgctttcgg tcgctaccgg tgactcggtg acgcttatct attcatgcct
     7681 gggctacaac aaggccgaaa ggatcctacc tcaagtaacc aaagatatgc gtctcaacgt
     7741 gcagatgaac tatacatcac tcgaactggg agaagtcgta gctaccgcca tccgaaagca
     7801 gacaaccact cttgaaaccc tgaatgccga ccgcgtcaaa ctactccccg accctgccgg
     7861 aggaagcatt gaaagtctgg tcgttacatt tgctggcgtt acttccaata acgaattaag
     7921 ttcgcaatac tccgtacgcg gcggcagcta tgacgaaaac atcgtatatg tgaacggact
     7981 ggaagtgttc cgtccgctgc tcatccgttc cggacaacag gaagggttga gttttatcaa
     8041 cccggacatg acggaagccg tcaatttctc cgccggagga ttcgaagccc gttatgggga
     8101 caaaatgagt tccgtgctgg acatcaccta caaaaaaccg aaaggattcg aaggttcggc
     8161 ttccgccagc ctgctgggag ccaatgctta tgtgggcagt tcttccggca agttcacaca
     8221 ggtgaccggt ttccgttaca aaacaggacg atctcttttg aaaacaaccg atacggatgc
     8281 cgaatatgat cctaatttca ttgatttgca gacttatata acataccagc ttgcccccaa
     8341 atgggagatc aactttctcg gaaacttagc cataaacaat tataagttca ttccccacac
     8401 ccgagagact tcttttggaa cggcaacaaa tgccaaaaaa tttaaagtat tcatgagtgg
     8461 ccaggaacgg gataagttcg aaacgttatt cggagcactc actttaaagc ataacctgaa
     8521 cgacaatacg gaactcggct tgcaagcatc cgcctttacc agtaaggaag aggaaggata
     8581 tgatattgcc ggtgattact ggctgggaga tgcagccgaa gaaggaggcg gagaaataca
     8641 gaatttatcc atcgcacgct ataacgagca cgctcgcaac cgtctgcact ccaatatcat
     8701 gaatgtcggg cattatggtg tcgctcgcat aaaaaacaat acgttgaaat ggggtgctac
     8761 cgtccagttg gagaaaatca acgacaagat cagcgaatgg gaaaaacgcg actccgccgg
     8821 atactcgtta ccgcaagggg gcgggaatgt caacgtgatc gcaaacctgt tctcggataa
     8881 caaactggaa agcacacgta tttccggcta tttgcaggat gtattcaagt ttcgtaccaa
     8941 acaaggactg ttcacgctgg ttggtggtgt acgcggcagc tattggagtt ataacaggga
     9001 atttatattc agcccgcgtg cttcaatagg tttcattccg aacttcgacc agaacctgac
     9061 atttcggctg gcttccggtc tgtattatca gtctccgttc tataaggaat tacgtacaac
     9121 tgtgcaggac gaatacggca acagtatcat acaactgaac aaaaacctga aatcacagcg
     9181 ttccatccat gtcattgcag gaggcgatta tacattccgg gcatccggca gaaatttcaa
     9241 agtcagtgcc gatatgtatt ataaaaaatt ggataacctg aacccctata cggtggataa
     9301 tgtcaaaatc cgatactacg gcgagaactg tgcgcaaggc catgcgatgg gactcgatgt
     9361 caaattcttc ggcgaatttg ttccgggtac ggactcctgg atcagcttct ccctaatgaa
     9421 agcggagcaa agcatccgag ggagcgaata tgtaccgatg cctaacagcc aaggttataa
     9481 tgtctcgctc ttttttcagg attatttccc cggatacaaa cgtgtcaaac tgaatctgaa
     9541 aggcgtactg tccggcggcc ttcccgtcac agccccacgt acaggctacg aggacggcta
     9601 tttccgtact ccgacctaca aacgcgtgga cctcggtttc tcctaccagc ttgccggggg
     9661 aacggatgca atcatggatc gcggattctt ccgcaatctc aagaacattt ggctcgggtt
     9721 ggatattttc aacttgttcg acataaagaa cactagttcc tattattgga ttaccaatat
     9781 agacaaccac cagtacgcta ttcctaatta cctgaccgga aggcaattga atattcgact
     9841 tatcgttgat ttttaaccac atgatttcaa aaatatgctt tttaaacata tctggatcat
     9901 gctgataaat attaacgaat tatttctcta ttaataaaaa gagtgtacct ttgccaacat
     9961 agaacaaaaa gcaatattaa attactaaat tattattgac atggaactta cacatatcga
    10021 acatttgggt atcgcagtaa agagcatcga agcttgcctg ccgtattatg aagaagtttt
    10081 aggactaaaa tgctacaaca tcgaagaagt agcagaccag aaagtaaaaa ctgcattctt
    10141 taaagtaggc cagactaaga tcgagttgct ggagccgaca agtgaagaca gtacaatcgc
    10201 taaatttatc gaaaagaaag gtgaaggtat ccaccacatt gcatttgctg ttcccgacgt
    10261 acaggcagca ttggacgaag ccgaatcaaa aggtatcaag ctgatcgaca aagctcctcg
    10321 tggaggtgca gaaggcttga acatagcatt ccttcacccg aaatcgacat gcagcgttct
    10381 gaccgaactt tgcatgccgg gaaaataaga aacaatggac aattgagaat tgacaattat
    10441 ttgatgctat tcaattggca attctcaatc gtcaattgcc aattaaataa gttcatttct
    10501 aacaacaaat ctatagtaca atgagtaacc aacttgaaaa agtaaaggag cttatcgccc
    10561 ttcgcgaaac agctcgttta ggtggtggag aaaaaagaat cgaatctcag cacaaaaaag
    10621 gtaaatacac cgcacgcgaa cgtattgcca tgttgctgga tgagggaagt tttgaagaat
    10681 tcgatatgtt cgtacaacat cgttgtacaa acttcggtat tgaaaaaact aagtatttgg
    10741 gcgacggtat cgtaacaggt tacggaacga tcgacggacg tctggtatat atttatgctc
    10801 aggatttcac tgtattcggc ggtgctttat ccgaagcact ggccatgaag atctgtaaag
    10861 tcatggatca ggcgatgaaa atgggtgctc ccgttatcgg cttgaacgac tcgggtggcg
    10921 cacgtattca ggaaggtgtc aacgccttgg ccggttatgc agaaatcttc caacgtaata
    10981 tcttggcttc cggggttatt cctcagattt ccggtatctt cggtccatgt gccggcggtg
    11041 cggtttactc tcctgccctg acagacttca atatcatgac ccgcggaaca agttacatgt
    11101 tcctgactgg tccgaaagtt gtaaaaacag ttacaggcga agacgttaca caggaacaat
    11161 taggtggcgc aagcgtacat acgaccaaat ccggtgtggc ccacttcgca gtcgatacgg
    11221 aagaagacgg tttacagttg atccgcaaat tgatcagctt cctgccgcag aacaacctgg
    11281 aagaaactcc tctgatcgaa tgtaaagacc cgatcgaccg tctggatgac aacctgaacg
    11341 acatcatccc tgacaatcct aaccaggctt acgatatgta tgaagttatc ggaaccatca
    11401 tcgataacgg cgaatttctg gaagtacatg ccgactatgc caagaacatt atcgtcggtt
    11461 tcgcccgttt taacggccag actgtcggta tcgtagccaa ccagccgaaa gtaatggcag
    11521 gctgtctgga cagcaacgcc tcccgcaagg caggccgttt cgtccgtttc tgtgatgctt
    11581 tcaacattcc tttggttaca ttggttgacg taccgggatt cttaccgggt acaggccagg
    11641 aatacaacgg cgttatcctg cacggagcca aattgcttta cgcttacggc gaagccacag
    11701 tgcctaaagt aactgtaaca ttgcgtaaat cttacggtgg tgcctattgt gtgatgagct
    11761 ccaaacatct gcgtggcgat atgaactacg catggccgac agccgaaatc gcagttatgg
    11821 gtccaagcgg cgctgtagaa gtgatctttg caaaagaagt ggctgcctcg gaagatccga
    11881 aagcttgcgc tgcagaaaaa gaagccgaat acaaaaaagc atttgcaaac ccatacaatg
    11941 cagctcaata tggctatatc gacgatgtta tcgaacctcg taacactcgt ttccgtatta
    12001 ttcgtgcttt acaacaattg cagaccaaga agttaagcaa tcctgccaag aaacatgaca
    12061 atctgcctct ataattctta aaacaggaaa tgaatatgat taataagaaa ataggggtat
    12121 tgctgctgtt cgcgttgctc gtttcattcg gggcaaaagc acagcgtgca acctccatgc
    12181 gaataaatga agtgctggtc atcaacgaag ataactttgt tgatgattac ggcaaacgcc
    12241 atgcctggat cgaattgttc aacaattcgg ccggttcggt caatatcgcc ggttgctact
    12301 tgactaatga caagagcaac ccgaaaaaat atccgattcc gaagggcgac gttctaacag
    12361 taattcctcc tcgccagcac actttgttct gggcagacgg agaaccggat cggggaacat
    12421 tccatgtcaa tttcacgctc gacccatcaa aagaaaatta cattgcgtta tacgatgcag
    12481 acggtaaaac tctgatcgat gagatcgtta tccctgcttc acaaaaagca gatgtcagct
    12541 atggtagaac tttagacgga caaggtgaat ggactgctct gacaaaagtt acacccagca
    12601 ccaataacgt aacattggat tctaacgaga aaatcgagaa ctttaaagaa aatgattctt
    12661 ggggtatcgg tatgaccctg actgccatgg cagttgtgtt ctccggatta ttcctgttgt
    12721 tcatcatctt taaacaaatc ggaaagctct cgatcgcggc cagcaaacgc aatgcacaga
    12781 aagcggccgg agcggctgtt attgcagaca atgcaggtca ggaatccggg gaaatctttg
    12841 cggctatcgg tgcggctcta tacgaaatga gcgacgacaa ccacgacatc gaacatacgg
    12901 ttctgacgat ccgcaaggtt caaagatctt attctccgtg gagttccaag atttacggtc
    12961 tgcgtgaagt tcccaaaaag taattatctc taaaaacaaa caagaatgaa aagttttaaa
    13021 tatactatta acggtaacgt atataaagta catatcagct cggtagtgga tgacatcgct
    13081 gaagtagaag taaacggtac tccctatcag gtaaaaatgg agaaaccggc aaaaaaacag
    13141 atggttacac tgaagcgccc ggctcaagct cctacaacgg caagtggcga accggttatt
    13201 tcccgtccgg cagcctcaac caccaagggc gctgtcaaat ctccgctgcc aggtgtaatc
    13261 ctgcaggtta actgtaaagt cggtgatact gtcaagagag gccagaatct acttgtcctc
    13321 gaagccatga agatggaaaa caacatcaat gccgaccgtg acggcaaaat cattgaaata
    13381 aaagtaaaca aaggggattc cgtactggaa ggtgctgacc tcgtcgtaat aggataatat
    13441 tatgttagga tcagtattat tacaggcagc aggtacggct catgaaagct ttctccagtt
    13501 cttgggagaa aacttggagt tgttcctcac ttatacagga gtctacaacg cgacaccggg
    13561 tcaccttatc atgatccttg tcggtctgtt gttcatcttc ctggctatta aatatgaatt
    13621 cgagcctatg ctccttatcc ctatcggatt cggtatcctg atcggtaaca ttccgttcaa
    13681 agatgcagga ttgcaggtgg gtatttacga acaaggttct gtgctgaaca tcctctacca
    13741 gggtgtaacc tccggatggt atccgccgtt gatcttcctc ggtatcgggg ccatgaccga
    13801 tttctccgca ttgatctcca atcctaaact gatgttgatc ggtgcagcgg ctcagttcgg
    13861 tattttcgga gcatatatca tcgctcttca aatgggattt gaaccgaacc aggccggtgc
    13921 aatcggtatc atcggtggtg ccgacggccc gacagcaatc ttcctttctt ccaagttagc
    13981 tccgaacttg atgggtgcta ttgcagtatc agcatactct tatatggcgc tggttcctat
    14041 tatccagcct ccgttcatgc gcctgctgac gactcagaaa gaacgtctga tccgcatgaa
    14101 accgccgaga gccgtttctt ccacggaaaa gatcgtattc ccgatcgtag gcttgttgct
    14161 gacttgcttc ctagttcctt ccggtctgcc tctgttgggt atgctgttct tcggaaattt
    14221 gttgaaagaa agtggtgtaa cacgtcgttt ggctgaaaca gcccgtggtc cgctgattga
    14281 tacaatcacg atcctgttag gtattacggt aggtgcttct actcaagcaa cccagttcct
    14341 gacattgaac tccatcaaga tcttcggttt gggagcgttg tcattcgtga tcgcaacttg
    14401 tgcaggtatc ctgttcgtga agttcttcaa cctgttcttg aaagaaggca ataagatcaa
    14461 tccgcttatc ggtaactccg gtgtgtctgc cgtgcccgac tctgcccgta tctctcagaa
    14521 cgtaggtctg gaatatgatc cgaccaacta cctgttgatg cacgccatgg gtccgaacgt
    14581 agcaggtgta atcggttctg ccgtagcagc cggtatcctg ttgggattct taggataatt
    14641 cacttattct acaaaaaaag gagctgaact ccaagtcatc tccaaatata aaaacttacc
    14701 caagtttacg gactttaacg tattcttggg taagtttgta tatgcgcaca acgattcatc
    14761 agaagtatat taatggctgc atcataaaaa actatttacg acacagcctc cctttttata
    14821 tccgacctta tcagatattt tgttcgacgg tcatcggatc tgtctctgga tttgcctcct
    14881 gttccaatgt tgtccccaaa aacaaccaaa tcattaacag gataatcgcg atcaccacac
    14941 caaagaccag cagtacattc gtattctttc gtctcatgtc cattcttcaa tattgatttg
    15001 aagattaaac aagacacccc cttttttggt ttaaccgttc cttacttttg ttctttattt
    15061 aactgagtaa atattttaga aagaatgttt ttttcttcac ttacaaatac agttggaaat
    15121 agacgatcca actatcatac catcataatt ggcaataacc cactatatat caacacaaaa
    15181 tagccatgac agttcgcaaa acaactgtca tggctactat cataccatca tacataaaat
    15241 tagtcaatca attatatatc aaccatctac ctcttccaca taataacaag tccccctcat
    15301 cgtccgctta ttcggcacgc tattccgctt caaaagcttg ccgaaattaa ggatcatcgt
    15361 ttttgtaatg ttaaaaccag gttgtttctc cgcgatcata tccagtatct cggacgccag
    15421 aagcggcttt gcctcttcaa tatcctccgc gatcttgaaa taacgcagga acagttgctc
    15481 ttcagccggc tgctgctgga aatccctgtt gttttcagtg atcagcgcct cttcctccgg
    15541 agtaaaccaa aaacgttcac cacgcctcaa caattctttc gcttccgcat acaactgatc
    15601 ataatcgatc ggctgggcat aatcgatccg gcccttcacc tccacgcaaa tgaaacggcg
    15661 gctaccggtc ggatccgtca gcaaatcata attgttgctg gtcgcgataa acgtggcata
    15721 gcgacgcaag ttacggctcg cactctgata aggcaaacgg gtgttcacaa ccgctttttg
    15781 caggatatgc ttcaaaaaac tttgatgaga acttttcact gaatcaaatt catcgatatt
    15841 aatcaacgca taccggtgca aagccaactc cgccccacgg cgattgccga aatcgatact
    15901 gtccgtataa taaggacgca acactggtgg caacaaattc aagcaaaacg tggacttccc
    15961 acacccttgg ccaccgacca acagaggtgt cgtactattc ctgtgttccg aatccagttc
    16021 catccaatgt gccaccatgc ttaggaacca gcggtaaaac aaatctcccc atatcggatt
    16081 gtcacaaggg acacgcccgg ctaatgccct gatgcgttct tttccgtccc aagccggaag
    16141 attcccaaga aaatggtcga taggatgata tatcggaaca cgatcggaat tgacataccg
    16201 gtcgatatcc ttgtcccata cattcaaccc ttcctgctgg gcttccaggc aaatggaatt
    16261 ccgaactttc gtcgtataag gcttgtaaac gaactgtatc atcgaacggt ccaaatattc
    16321 cactccaccg ctcatctcat tcgtccggaa gaaataacgc cggttcataa actcgtccaa
    16381 ccgcaacacc aacgacatgg atggcgggac ggaagagagc ggctccgctc ggtttgaaac
    16441 attctccaac gtatatgccg tacggaaagc catacggacg tctatcttat attttttcaa
    16501 agcctcatag cgcaatgtcc agcccaccgc ctcttcctcc ggtattccaa gccggcagca
    16561 agcttgcgcc aagtcgatga acagcagttg gatatcatct tccgggcttt ctgaaaaccg
    16621 gcgcgtcatc tccatcagga tgacactgaa cagcgtggcg atctgcccgt tccgatccgc
    16681 tcccggagcc atcatctcca acggatcccg aaccggagaa ggcacgatct tcaagtcacc
    16741 cccgtccggc atctgcaaag gttgctcgat ccggatcgcc accgcatccg gattgtaata
    16801 ggcgtccgga tccacactca tccggcaccc ccgcgacagg aacggttctt tcaacgatat
    16861 aatgctgccc aactgcggct ggtaatgccg caccgccagc tgataagccg cagcatgaaa
    16921 catacgggcc tgctcctctt ttttcggcag cgagccgtcg ggcagcacaa aaggaaccac
    16981 gatcttgacc gaacgcccgc tcagcccgac gaacgccagc aaggtctgcg gcagggcggc
    17041 agcttcacgg cggacggcct ccgcctcact ctggctttcc aagccgttca cttccaacaa
    17101 gacatacccg ttatagcgcc tcaactgtat tccatcgcca ttcttcttga acgtcgagcc
    17161 aaaagccaga accggtagtt ttccggacaa atccgtggtt cgtgccaaaa acgccatatt
    17221 caattttcga cgaaccgaca gtatcgcttc cgcatctttg ccgtttttca gcaacccgac
    17281 aatatattcc atatcacgcg agtgcatccg caacacgcct tttttatgcc tgtaatatgt
    17341 gatttgcatt accaaggatt tctttcgaat ttgacaaatt tcatgctctt tctcacacag
    17401 ggagccatcc tgaaacagac acgacgcgcc ttcacccgat ggggagtaca ttttttcgga
    17461 tcttcgaagc cttcgctccc tgccgaaaga taaaaatcac ccaacccgtc caactccacg
    17521 gaatagccgt ctttcaacaa ttcaagaatc atccctccga tctcgcaaac cgaagcgaac
    17581 acatcacctc ggctcaacga gcaacgatcg gcaaccaaat cagccagctt tttcgttgaa
    17641 acccgcccgc acgtaaccgg aacaccataa tagcgtactt tatcttccgc tcccgtcttg
    17701 tccagttttt gccggactac atagtaatgt gccataaata acagtatttt taatattaaa
    17761 caaccagata ttcttctcaa gacgcccatt ttaacacttt tgacaccccc atctgaacgg
    17821 tatcagcacc cgggtctcac cccttccgac acccggatga cgggcttctt ttcttattac
    17881 aaatatacta ataaaacatc tataatgcaa atatttacag cactttattc aattatatct
    17941 acacttattt ttccccagca taaagacaga agcatgtgat atacgacatg atagtatgat
    18001 agtatgaaat gatagttgaa aatagatact atcatatttt aataaactaa tatacagaca
    18061 tttataagaa aatatgatag tatgatagtt ggatttaaaa aaaatcatat gtatataata
    18121 ggtggatgtt tacagcagct tatttatatt gcttgcagga ggaagactta catggatggc
    18181 aaccctaaac taacacatcg tcctgtttcc atgtttgaca ttgtagctat caaacacaag
    18241 aaacaggacg attttgcata tctaagttct tttccgattg accggactta cataaaaatt
    18301 tcgacaaacg tgccattccg acatagtaca caactacatc atcgagctaa aagcacctta
    18361 ttttttgcaa ccgtcgcctg aaactctttc aggtagaacg gttcgaaata ggcggtgtct
    18421 tcaaacttgc cggcggcaaa agcttgttcc gagagcggaa tcatgtttac ggcaagagga
    18481 tggatgtcct cgataaagat ggcattcgga gaagtgatga ccgatttgca tttggaagca
    18541 ccgttgccaa agaaacaaac tttccctttt tccagataag aagcatacgt gccgacttcc
    18601 acaatatcgg ccttcgtctc gcggacaggc tttaaggaag catcgtagat agcggcataa
    18661 acctccatac gccgggcatc caacatagca caataaaggc aattatcagt aatagagacg
    18721 atttgcgaat cacccttact gttgacagta gcagccatga tgtccaacgt atgaatgccg
    18781 atcagaggaa taccgaaacc aaagcaaaga cctttagcga cagacactcc gatacggagt
    18841 ccggtataag aaccaggacc gctactgacc gctacggcat ccaaggcttt cttccccttc
    18901 tttttcaata cggaaagagc ttcttcaaca aatacgccta atagggctgc atgcgaaggg
    18961 ccgtcgaacg aagccttcgc aaaaaggact tcaccatcca tagacaacgc tacagagcat
    19021 acagaagtcg atgtttcgat atttaatata caagacattt taattgacaa ttgacaattg
    19081 acaattgaca attagaatat gtgtcaaaag ccaatcggtt gataatggat gcaaaagtat
    19141 aaaacataac tgtaatctca tgatcaaaac cgattttatt aaggctgaca cggatggttt
    19201 cggctttttc ccaattatat tgtcaatcgt caattgtcaa ttatcaattg attagctatc
    19261 tttgcacaaa tttttagaac aatgatacaa tcaatgactg gattcggtaa ggttacagcc
    19321 gaacttcctt ctaaaaaagt aaccgtagaa ataaaagctc tgaacagcaa gcaactggat
    19381 ttgtcgaccc gcattccttc catctacaaa gaaaaagaaa tgcaaatacg cagtttgtta
    19441 ctccagtcgc ttgaacgtgg aaaagtcgaa tttaatatat ttgtcgaata tatcggtaaa
    19501 gacacgccca cacagatcaa cttggctgcg gtagaaaact attacaatca aatcaaagat
    19561 attgccgacc gcctgaacat cggacttccc gccgactggt tccagaccct gctccgcatg
    19621 ccggacgtga tcaagacaga ggcccaggaa gtaaacgaag aggaatggaa tgtggttgag
    19681 aaagcgatca aagaggccat agggcacctt tgcgatttcc gtattcagga aggcgccatg
    19741 ttacaaaagt tgttcgaaca gaaaattgcc aatatctccc gcctgctttc agaagtagaa
    19801 cagtatgaaa aggagcggat cgaaaaaatc aaagcccgta tcatggacaa tctcgaaaag
    19861 attgccggac aggactacga caagaaccgg ttcgaacagg agatgatcta ttatatcgaa
    19921 aaactggacg taaacgagga aaagaaccgc ctggacaacc acctgaaata ttacatcagc
    19981 acgatggaga gcggacacgg acaaggtaag aaactcggtt tcatcgccca ggaaatggga
    20041 cgtgaaatca acacccttgg ttcgaaaagc aaccatgccg agatgcaaaa acttgtcgtc
    20101 cagatgaaag acgaactgga acaaatcaaa gaacaagtat taaacgtatt ataaaaacga
    20161 tatatggctg gcaaactgat catattctcc gcgccgtccg gttcgggcaa atccactatc
    20221 atcaatttcc tgctgaagca gaatctgaac ctgcattttt ccatctcggc taccagccgg
    20281 gccccacgtg gtacggaaaa ggacggagtg gaatattatt tccttacacc agatgaattc
    20341 cgtgcccgta tagcagcagg agatttcctg gaatacgaag aggtctatac cgacaaatat
    20401 tacggcacgc tgaaaagcga ggtggaacga aggctgatga gtggcgataa cgtcatattc
    20461 gatgtcgatg tcgtaggagg ttgcaacatc aagaagtttt atggcgaccg tgctctttcg
    20521 gtctttatcc agcccccttc gatcgaagat ttgcggagtc gtctggaagg acgcggtacg
    20581 gatgctccgg aagtaatcga aagccgcatt gccaaagccg aatttgaact gggttttgcc
    20641 gacaaatttg acgtaatcgt ggtgaacgac aagttggaag tcgcagaaaa agaagcacta
    20701 aaagtgataa aagagttcct taaaaaagca tgaacggcaa gaagttatcc aagaaatggc
    20761 tatatacatt cattggtata gcatttgtcg ctcttgccac ttgtacagcc gccctatatt
    20821 ataaggagta tatcatagcg accggtaccg gattggtatt cggtgcacaa gtcataaata
    20881 tcatcaagtg gaaacgggac tgaaagaaaa tacggccagc aaacgtaaaa ccggcattta
    20941 ttccggttca ttcaatccgg ttcatatcgg ccatctggca ttagccaact ggttgtgtga
    21001 atttacggag ctggacgagc tatggtttct gatcaccccc cacaacccgc taaaagagaa
    21061 ggaagaactg atggatgacc ggcttcgcta tgaactggtt aaaaaatcca tcgctggtta
    21121 ccctaagttc cacgccagtg acttcgagtt ttcccttcct caacccactt ataccatcaa
    21181 cacactccgg acattggaag caagttatcc ggaccgtgaa ttctatttca tcatgggtgc
    21241 ggacaattgg aaatatatta cccggtgggt agaatacgaa gccatcattt ccaattatcc
    21301 gatcttcatc tatccgcgca aaggattcaa tgttgaaatt ccggcacaat atcctcacat
    21361 aaaaaaagta gacgcccctt tggtcgaaat atcctcaacc tttatacgcg aagctttcaa
    21421 gaccggaaaa gatgtccgct tcttcctgcc cgaagccata cgtaatctgc cttttccatt
    21481 acaaaacaat accttttaag aacataaagc gtaaagtcgc atacgttttt aggcaataag
    21541 taagaaaagt tttgtatttt tgcgccgtat tatacaaaat aatagcgtaa tgaatctatt
    21601 agaactgagt gaacaggaaa tcataagacg taacagcatg gagcagttac gccagatggg
    21661 gatagaacct tatcccgcag ctgagtatgt aacgaatgca ttttccaaag agataaaaga
    21721 gaattttaaa gacgatgcag agccccgccc tgtaagtatt gccggtcgca tcatgagccg
    21781 ccgcatcatg ggaaaggctt ccttcatgga attgcaggat tcagaaggca gaatacaggt
    21841 ttatatctct cgtgacgaca tttgcccgga agaaaataaa gatctgtata acattgtttt
    21901 caagaaattg ctcgatatcg gcgactttgt cggaatcaaa ggtttcgtat tccgtacaca
    21961 gatgggcgaa atttccgtcc atgcacaaga gataacggta ttatccaaat cactcaagcc
    22021 gctaccggtc gtcaaataca aagacggtgt agcatacgat ggattcaacg atccggaatt
    22081 gcgttatcgc caacgctatg tcgacctggt ggtcaatgat ggcgtaaagg atattttcat
    22141 gaaacgtgcg gcagttatca agaccatgcg taccgccctg gacgaagctg gatatacgga
    22201 agtggaaact ccgatcctgc aatccattcc cggaggggca agcgcacgtc cgttcattac
    22261 gcaccataac tcgctggata tcgacctcta tctgcgtatt gctaccgaac tgtatctgaa
    22321 acgattgatc gtcggaggtt tcgaaggtgt ctacgaaatc ggtaaaaact tccgtaacga
    22381 aggtatggat cgcacccaca atccggaatt tacctgtatg gaactttatg tccaatataa
    22441 ggactacaac tggatgatga gcttcaccga acagctgttg gaacgtatct gtatcgccgt
    22501 caacggtaca tgtgaaagtg tagtcgacgg caagaccatc aactttaaag ctccttaccg
    22561 ccgtctgccg attctggatg ccatcaagga aaagacaggt tacgacctga atggcaagag
    22621 cgaagacgag atacgcacga tttgcaagga tttgaacctt gaaatcgatg aaacaatggg
    22681 taaaggcaag ctgatcgatg aaatcttcgg tgaattctgt gaaggcacgt ttatccagcc
    22741 gactttcatt atcgactacc cggtcgagat gagtccgcta accaagatgc accggagcaa
    22801 acctggattg accgaacgtt tcgaattgat gatcaacggt aaagaagtgg caaatgccta
    22861 tagtgagctg aacgatccga tcgatcagga agagcgcttc aaagagcaat tgcgcctgag
    22921 cgaaaaaggg gatgacgaag cgatgttcat cgaccaggac tttttgcgtg cactgcaatt
    22981 cggtatgcct ccgacgtctg gtatcggtat cggcatcgac cgtctggtga tgttaatgac
    23041 tggccaaacg actattcaag aagtgttgct cttcccgcag atgcgcccgg aaaagacagt
    23101 taagaaagac accgcagaca aatatgtcgc actgggtatc gatgaagcat gggttcctgc
    23161 tttacataaa gccggatatc tcacaaccga cacgttggta gatgctaatc ccaacaagct
    23221 gagacaggaa ctctgcgaaa tgaataagaa atacaaactg gaattgcaaa accccactgc
    23281 cgaagaagta gaggcatgga ttgcaggcgc agccaaataa gagtaatact atgaagttgc
    23341 ccggaaaaat tgcaataatg ggaggtggta gctgggctac cgccttggcc aagattgtac
    23401 tttctacaca agatagtatt aactggtata tgcgtcggcc agaccaagta gaagagtttc
    23461 tgttgttggg acataacccc agctatcttt ccgccgtcaa atttgatact gacaaaatca
    23521 aattctacac ggatatcaac aaagtaatca aagattcgga cactttgatt ttcgccaccc
    23581 cttctccttt tttgaaacaa catttgatga aggtgacgac ctccatgcaa gacaaattca
    23641 tcatttcggc catcaaagga atcgttccgg acgaaaacat gctcgtagcc gattattttg
    23701 ccgaatacta caatgtcccg attgacaata tcgctgtcat cggcggtccg tgccatgccg
    23761 aagagatcgc tctcgaacgg ttgtcctata tcacgctggc ttgccctaat atcgagaatg
    23821 caagagcttt ctcctccgta tttaagaacc aatatctgaa caactcctgt tgcaaggatg
    23881 ttacaggtat tgaatatgct tccgtattga aaaacgtata tgccatcgtc gcaggtatct
    23941 gccacggtat gaagtacgga gataattttc tggcagtttt catctgcaac gcgatcgaag
    24001 agatgcgtaa cttcctcaac gccgtacatg gcctggaacg ggatgtgaca gattcggtat
    24061 atctcggtga tcttctggta accgcatatt cccgcttcag ccggaaccgt acgttcggga
    24121 ccatgatcgg gaaaggttat tccgtcaaaa tagcccagct cgaaatggag atgatcgccg
    24181 aaggatatta cgggacaaaa tgtattcggg agataaacga aaaatataaa gtaaacatgc
    24241 cgatcttgga tactttatat agtattctat acgaaaagaa atcgccgact accgcgatac
    24301 ggcagttgac tgaaacattt aaataataat gtaaatatga agaacatcag tcttaacatt
    24361 gacaaagcgc tgggtactgt gacgaaagaa caggtgtatg ctcaggctgc aaaggcccac
    24421 gaatgtaatg tcactttaca aaatggtaat ggtgcaggta acgacttttt aggttggttg
    24481 cacctcccct cttctattac agatgctgaa ctgacagaca tcgaaaatac agctaacgta
    24541 cttcgttcta aatgtgaagt tgttgtcgcc atcggtatcg gcggtagcta tttaggaaca
    24601 aaagcagtgg tagaagcatt aaacaatagc ttcgactg
//
