LOCUS       gnlProkkaBGBOAMNL_2    13618 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BGBOAMNL_2.
ACCESSION   gnlProkkaBGBOAMNL_2
VERSION     gnlProkkaBGBOAMNL_2
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 13:48:46
            Original ID  :: gnl|Prokka|BGBOAMNL_2
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 179640
            Orig. end    :: 193258
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13618
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10348]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10348
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13618
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13618
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2006..3043
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_128"
                     /sec_met_domain="PF04055 (E-value: 1.1e-16, bitscore: 54.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMSKYPLLGMTLIELQSLVKRLGMPGFAAKQIASWLYDKKVTSID
                     EMTNLSLKYRELLKQNYEVGAEAPVEEMRSVDGTVKYLYPVGENHFVESVYIPDDERAT
                     LCISSQVGCKMNCKFCMTGKQGYSANLTAHQIINQIHSLPERDKLTNVVMMGMGEPLDN
                     LEEVLKALDILTGSYGYAWSPKRITVSTVGLRKGLRRFIEESDCHLAISLHSPVTAQRA
                     ELMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCR
                     INLIRFHSIPGVALEGADMDTMTRFRDYLTTHGLFTTIRASRGEDIFAACGMLSTAKQE
                     ENNKS"
     CDS             3061..4098
                     /locus_tag="ctg2_129"
                     /transl_table=11
                     /translation="MKKYFFYLSMALVAFVVASCGLKGNHTSSGRPYELLVVVDAGVWD
                     RAAGRALHDVLDSDMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIVIVDIKDIYTKGTF
                     KYAKDVYASPQMILTIQAPNEEVFEKFVEENKQTIIDFFTRAEMNRQITLLEEKHNNFI
                     SNKVDSLFGCDIWIPSELNNSKTGEDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGYKEGVYMSTDSLLTDVRPINVHNDYTMEARGLWRMKGDFMGGPFV
                     SHTRLDQKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPQEGQQSQIPLGVTKEA
                     EPTNK"
     CDS             4104..5198
                     /locus_tag="ctg2_130"
                     /transl_table=11
                     /translation="MEENKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDVQANFSIVNTASEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGNKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEIIIPAMKEMEEKGIICYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLASEDSFRQAIYVAIDVFRNRQREKAARIN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             5322..6563
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 388.9; E-value:
                     5.7e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg2_131"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFAADFAEKYRMPAIQLTEDAKKI
                     LLAYPWPGNVRQLKNITEQISIIETNREITAAILQTYLPAQNTQRLPTLFGTRESKSFE
                     SEREILYSVLFDMRQEVAELKKMVHNMMAERAGQVGQMGQVVATPVVTTTHQPSVPAII
                     HAVQQPSVCPKEDDDDIQDTEEYVEETLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             6550..7077
                     /locus_tag="ctg2_132"
                     /transl_table=11
                     /translation="MNWIKKIARPLILVVLPAVIIACSVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             7082..7876
                     /locus_tag="ctg2_133"
                     /transl_table=11
                     /translation="MTSVNLQQWIQHPETLNRDTLYELRNQLARYPYFQSLRLLYLKNL
                     YILHDINFGAELRKAVLYIADRRKLFHLIEGERFAVESQKKGLPLSEVLKDEPTVDRTL
                     ALIDAFLSTAPEEVTSQTSFDYSMDYTAYLLEETPVADEPAEAMPKLKGHELIDNFIEK
                     SETDPVVYLKPLREEEKAKAASSAETNETGRTDETTETNTVEEEDDSCFTETLAKIYVK
                     QQRYSKALEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             7883..8278
                     /locus_tag="ctg2_134"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPAAE"
     CDS             8569..9957
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 91.3; E-value: 8.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_135"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             10001..10348
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_136"
                     /sec_met_domain="PF05402 (E-value: 5e-17, bitscore: 55.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.1e-09, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQHEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(10338..10625)
                     /locus_tag="ctg2_137"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(10647..11711)
                     /locus_tag="ctg2_138"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             complement(11785..13296)
                     /locus_tag="ctg2_139"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTSEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRSEETEAALIEQ
                     LEHCQTPTVVDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
ORIGIN
        1 cgttaataac aaactggttg agaaagaagc aaaagcattg ggactgacag tttctgctgc
       61 tgaaattcag gatatcctga aagcaggcgt gcatccgttg ttgcaacaga ctcctttccg
      121 caacccgcag accggtgctt tcgataagga tatgctcaat aagttcctgg tagattacgc
      181 taaaatgaac gaatctcaga tgccggctca gtatgcagaa cagtacaaca acatgtacaa
      241 atactggtca ttcatccaga agacattggt tcagagccgc ctggcagaga aatatcaggc
      301 attggtagca aaagcgcttc tctctaaccc ggtagaagca caggacgctt ttgacgcaag
      361 agtgaatcaa tatgacttgt tgatggctgc cgttccttat tcttctatag tagattctac
      421 aatcgttgtg aaagaatcgg aactgaaaga cctttataac aagaaaaaag aacagttcaa
      481 gcaatatcag gaaagccgtg atatcaagta cattgatgtt caggtgactg caagtgcgga
      541 agacagagct gctatccagc aggaagtaga cgaagctact gcacagctgg ctactacaac
      601 agatgactat acttctttta tccgttctgt aggctcggaa gctccttatg tagacttgtt
      661 ctataataaa acagctttcc cgtcagatgt agttgcccgt ctggactctg catccgttgg
      721 ttctgtttat ggtccgtact ataatggtgc cgacaatact atcaattcat tcaaagtggt
      781 tgcaaaaaca gctgctgccg actcaatcga gttccgtcag attcaggtgt ttgcagaaga
      841 cgctttgaag acaaaagcct tggcggacag tatctatact gctatcaaag gcggtgctaa
      901 cttcgcagat ctggctaaga aatacggtca gacgggtgag actaactgga tgagctctgc
      961 acagtatgaa ggcgcacaga tcgatggtga caacctgaag tttatctctg ctatcaataa
     1021 tacaggcgtg aacgaagtag taaacctgcc gttgggacaa gctaatgtaa tcctgcaagt
     1081 gactaacaag aaagctgtga aggataaata taaagtagct gttgtgaaac gtgaagttga
     1141 attcagcaaa gaaacttata accgtgctta caatgatttc agccagttca tcgctgccaa
     1201 tcctactgct gaaaagatga tcgctaacgc tgaagaagcc ggatacaaac tgcttgacag
     1261 aagagacttg tatagctcag aacatactat cggtggtgta agaggtacta aagaagcatt
     1321 gagatgggca ttttccgcta aaccgggtga tgtctccggt ttgtatgaat gtggcgaaag
     1381 cgaccatatg gttgcagtag ctctggttgg tgttactccg gaaggatatc gtccgctgaa
     1441 agctgtacag gatcagttga gagctgaaat cgttaaagat aagaaagccg aaaagatcat
     1501 ggctgacatg aaggctgcca atgcaacttc tctcgaccag tacaaggcta tgtccggcgc
     1561 agtcagcgat tctttgaagc tggttacatt tgccgctccc gcttatgttt ctgcattgcg
     1621 cagcagcgaa ccgttggtag gtgcttatgc ttctgtggct gaaatgaata aactgagcgc
     1681 tccgatcaaa ggtaatgccg gtgtatttgt gcttcagatg tatggcaaag acaaactgag
     1741 cgatactttc aacgctaaag atgaagaagc tacattggct aacatgcacg cacgcttcgc
     1801 aagccgtctg atgaacgacc tgtatctgaa aggaaaagtg aaggatacac gttacctgtt
     1861 cttctaagat tagtcgtaaa aacgataact gcaaaaggtc gttccatgct ttggaacgac
     1921 cttttttgct aacttttaca tccttgctat acggaaatcg actttatttc cttacatttg
     1981 caaatataaa ccatgaacag aaagaatgat gtctaaatat cccctcttag gaatgacgct
     2041 tatagagctg cagtcactgg tgaaacgtct gggaatgccg ggctttgcag ccaaacagat
     2101 tgcatcctgg ctttatgata agaaggtgac ttcgattgat gaaatgacta acttgtcgtt
     2161 gaaataccgg gagttactga agcagaacta tgaggtagga gctgaagctc cggtggagga
     2221 aatgcgctct gtagacggta cggtgaaata cctgtaccct gtgggcgaga atcattttgt
     2281 ggagtcggtg tatattccgg atgatgaacg ggcgacttta tgcatttctt cgcaggtagg
     2341 ctgcaaaatg aactgcaagt tctgtatgac cgggaaacaa ggctactctg ccaacctgac
     2401 cgcccatcag attatcaatc agattcactc cttgccggaa cgggacaaac tgacgaatgt
     2461 cgtcatgatg ggaatgggcg aaccgctcga taatctggaa gaggtgttga aggcattgga
     2521 catactgact gggtcctatg gttatgcatg gagtccgaag cggattaccg tttcaactgt
     2581 cggattgcgg aaaggattgc ggcgctttat cgaagaaagc gactgtcacc ttgccatcag
     2641 cctgcattct ccggtgaccg cccagcgtgc ggaactgatg ccggcggaga aagccttttc
     2701 tatcacggaa atggtggaac tgttaaaaaa ctatgatttt agcaaacagc gtcgactttc
     2761 gtttgagtat attgttttta aggggcttaa tgattcgcaa gtttatgcca aggagttact
     2821 caaactgctt cgcggactgg attgccggat taacctgatc cgtttccatt ctattccggg
     2881 agtagccctt gaaggagccg atatggatac aatgacccgt ttccgtgact atctgaccac
     2941 gcacgggctt ttcactacca ttcgtgcttc gcggggagag gatatttttg cggcatgcgg
     3001 tatgctgtcg actgcgaaac aggaggaaaa taataaaagt taatataaaa atcgaacatc
     3061 atgaaaaagt acttttttta tttaagcatg gctctggtag ccttcgtagt tgcttcttgt
     3121 ggattaaagg ggaatcatac ctctagcggt cgtccgtatg aactgttggt tgtagtagat
     3181 gcgggagtgt gggaccgtgc cgccggaagg gccttgcatg atgtgcttga ttctgacatg
     3241 ccgggactgc cccagtcgga accttctttc cggattatgt atacttcacc gaaggactat
     3301 gattctacgc tgaagttgat ccgtaatatt gtgatagtag atataaaaga tatttatacc
     3361 aaaggtactt tcaagtatgc gaaagacgtt tatgcttctc cacagatgat actgaccatt
     3421 caggctccga acgaagaagt gtttgagaag tttgtcgaag aaaacaagca gacgattatc
     3481 gacttcttca ctcgcgctga aatgaaccgt cagattactt tgctggagga aaagcacaac
     3541 aactttatct caaataaggt agatagtctg tttggctgcg atatctggat accttccgaa
     3601 ctgaataact ccaagacagg agaggacttc ttctgggcat ctaccaatac aggcagcgcg
     3661 gatcgcaatt tcgtgatgta ttcttatcct tatactgaca aggatacatt caccaaagaa
     3721 tactttgttc ataagcgcga ttctgtgatg aaagccaata tccccggata taaagaaggc
     3781 gtatatatgt cgacagactc gttactgacc gatgttcgtc cgatcaacgt gcacaatgac
     3841 tacacgatgg aagctcgtgg attgtggcgc atgaagggtg acttcatggg tggcccgttc
     3901 gtttcccata ctcgtctgga tcagaagaac caacgtatta ttacagcaga aatatttgta
     3961 tattcacccg ataaaatgaa acgcaatctg gttcgccaga tggaagcatc tctttatacg
     4021 ctgaaacttc cgcaagaagg tcagcagagc cagattccac tgggggtaac caaagaagcg
     4081 gaaccaacta ataaataaaa aacatggaag aaaacaaaat aagaatcggc attacccaag
     4141 gagatatcaa cggggtaggt tatgaagtga tcttgaagac attctcagac cctaccatgc
     4201 ttgagctatg tactccgatt atctacggtt cacctaaagt agcggcttac catcgtaaag
     4261 cactggatgt acaggctaat ttcagcattg tcaacactgc ttccgaagcc ggatacaacc
     4321 gtctgagtgt agtgaactgt acagatgacg aagtgaaagt ggaattctcc aaacccgatc
     4381 ccgaagcagg taaggctgca ttgggtgctt tggagcgtgc catagaagag tatcgtgagg
     4441 ggctgatcga cgtcattgtg acagctccga tcaacaaaca taccattcag tcggaagagt
     4501 tctctttccc cgggcatacg gagtatattg aagaacgtct gggcaatgga aacaagtcac
     4561 tgatgatcct gatgaaaaac gattttcgtg tggctttagt aacgacgcat attccagtaa
     4621 gggagattgc tacaacaatc accaaggaac tgattcagga aaagctgatg attttccatc
     4681 gttgtctgaa acaggatttc ggtatcggtg cgccccgtat tgcagtgctt tcactgaatc
     4741 ctcatgcagg agacggcgga ctgctgggta tggaagaaca ggaaatcatt atccctgcca
     4801 tgaaagaaat ggaagagaaa gggatcatct gttacggtcc ttatgctgcg gacggtttta
     4861 tgggttcggg caattatact cactttgacg gaatccttgc tatgtatcat gatcagggac
     4921 tggctccgtt caaagccctg gctatggaag acggtgtgaa ctataccgcc ggactgccgg
     4981 ttgtacgtac ctctccggct catggaacag cctatgacat cgccggtaaa ggactggcca
     5041 gcgaagactc tttccgccag gctatttatg tagcgattga tgtattccgc aaccgccagc
     5101 gcgagaaagc ggcacggata aacccgttgc ggaagcagta ttacgagaaa cgggacgata
     5161 gtgataaact aaaactggat acagtagacg aagattaagt aataggtatt aagtaataag
     5221 tattaagtat tagccatgcg gatagaagcg agatgatagt gatggtaata cttaatactt
     5281 attacttaat acttattacc tattacttaa tattaagata gatgaccaaa gcagagatac
     5341 aacaagtgaa acagcgtttc ggtattattg gcaataccga ggctttatca cgtgccatag
     5401 atgttgccat tcaggtagcg cctaccgatt tgtctgtgct gattaccgga gaaagtggtg
     5461 tcggaaaaga aagttttcca cagatcattc atcaatatag ccggagaaag catgggcagt
     5521 atattgctgt caactgtggt gccataccgg aaggtacgat cgattccgaa ctgttcggac
     5581 acgagaaagg agcatttacc ggtgctattg gtgagcggaa aggatatttt ggagaagctg
     5641 acggtggaac tatcttcctt gatgaagtgg gagagttgcc gttgcctaca caggcgcgtc
     5701 tgctccgtgt acttgaaagc ggtgaattta tcaaggtagg ttcatccaaa gtgcaaaaga
     5761 cggatgtacg tattgtggca gcgaccaacg tgaacctgac acaagccatt gccgaaggac
     5821 gcttccggga agatttgtat tatcggttga acacggtgcc tattcagata ccacctttgc
     5881 gtgagcgtgg agatgatgtg ctgttgttgt tccgtaagtt tgccgcagac tttgccgaaa
     5941 agtaccggat gccggctatc cagctgacgg aagatgccaa gaagatattg cttgcttatc
     6001 cgtggccggg aaacgtccgg cagttgaaga acatcacaga gcagatttcg attatagaaa
     6061 caaaccgtga gataacggct gcgattctgc agacctatct tccggcacag aatacccaac
     6121 gccttccgac actgttcggc acacgcgaga gcaagagctt tgagagcgaa cgcgaaatac
     6181 tatattctgt cttgttcgat atgcgtcagg aagtggcgga actgaagaag atggtgcaca
     6241 atatgatggc cgaacgtgcg ggacaagtcg gacagatggg acaggtagta gctactccgg
     6301 tagtgacaac gacgcaccaa ccttccgtgc cggccattat ccatgctgtg cagcaaccgt
     6361 ctgtttgtcc caaagaagac gatgacgata ttcaggacac ggaagaatat gtagaagaaa
     6421 ccctttcgct cgatgaagtg gaaaaagaaa tgatacgtaa agcgcttgag aggcatcatg
     6481 gtaagcggaa aagtgcggcg aaggatctga atatctccga gcgtaccctt tacagaaaaa
     6541 taaaagaata tgaattggat taagaaaata gcacgaccgc tgatattggt tgttttaccg
     6601 gcagtcatca tcgcctgtag tgtgtcctat aagtttaatg gctcctctat caattacgat
     6661 aaggtgaaga ctatttcgat tgctgatttc ccgattaagt cggagtatgt gtatgctccg
     6721 ctggctacca agttcaatga agacctgaaa gatatcttca tcagacagac ccgtctgcaa
     6781 ctgctgaaac cgaaccagaa tgcggatctg cagattgacg gtgaaattac gggctacaac
     6841 cagtataacc aggcagtgtc tgccgatggt tactcttcgg aaacgaagct gaccatcacg
     6901 gtcaatgtac gctttgtcaa caacacaaat cacgccgaag acttcgaaca acaattctca
     6961 gctttccgta cctatgattc cagccagctg ctgacagccg tacaggatgg attaatagcg
     7021 gaaatgagta aagagataac cgaccaaata tttaatgcaa ctgtagcaaa ctggtaattt
     7081 aatgacttct gttaacttgc aacaatggat tcagcatccc gagacgctga atagggatac
     7141 tttgtacgaa ctgcgcaacc agctcgcgag gtatccgtat tttcagtcgc tccggttgtt
     7201 gtatctcaag aacctgtata ttctccacga cattaatttc ggtgcggaac tgcggaaagc
     7261 cgttctgtat attgccgacc gacggaaact gtttcatctg atcgaaggcg aacgcttcgc
     7321 tgtcgaatcc cagaagaaag ggttgcctct ctctgaagta ttgaaagatg agcctaccgt
     7381 cgaccggaca ctggctctga tcgatgcttt cctttcgacg gctcccgaag aagtaaccag
     7441 tcagacaagc tttgattact ccatggacta tacggcatac cttctcgaag agacacctgt
     7501 cgccgacgag ccggcagagg caatgcccaa gctgaaagga cacgagctga ttgacaactt
     7561 tatcgaaaaa agcgagactg atccagtcgt atacctgaaa cctttgaggg aagaagagaa
     7621 agcaaaggca gcttcttccg ctgaaacaaa cgaaacgggc agaacagacg aaacaactga
     7681 aaccaacacc gtagaagagg aagatgacag ctgtttcaca gaaactttgg ccaaaatcta
     7741 cgtaaaacag caacgatatt cgaaagctct tgaaataatt aaaaaattaa gcttgaaata
     7801 tccaaaaaaa aatgcttact ttgcagacca aatcagattt ttggagaaat tgattattaa
     7861 cgctaattca aaataactaa aaatgtactt attattcatt atcttaatgg tgattgcagc
     7921 cttgctgatg tgcttcatcg tgctgattca gaattcaaaa ggaggcggac ttgcttctgg
     7981 tttttcttca tcaaacgcta tcatgggcgt gcgcaagact acagattttc tggaaaaagc
     8041 aacttggggt ctggctatct tcatggttgt gatgagcgtt gctactgctt acgttgttcc
     8101 ttcttcttct gcagctaaag atgtattgtt ggaacaagca cagaaagaac aacaaaccaa
     8161 cccgtataat atgcctaccg gtactgctgc tcctcagaca gacgctactg ctcctgcaga
     8221 gtctgcacca gcaacagaag ctccggctac tgaaactcct gctcctgcag cagaataatt
     8281 cagtgacagg atattcggtt taaacttatt gagtgaatgg gctttttgac ccgttctctt
     8341 cattataggc gcgaattacg cgaattacaa gagattctaa tagaatcgtg taatacgtgt
     8401 agttcgcgcc tgtctttatt attgggtccg gtctgctctt cttcatacag gaatatccgg
     8461 ttagatgtcc tttttcttat aaaatgttct ccttttttag taaaacaaat gataattagt
     8521 taactttgtt gcccgttacg agattattaa ctccttttaa atattacaat gacagaacaa
     8581 ttgaaacaaa agctgaatga ctccgcagtg ctgcgttgga gtgttctagc attagtcgct
     8641 tttaccatgt tgtgcggcta cttcctcaca gacgttatgt ctcctctgaa acccatgctt
     8701 gaaaaagaac ttctctggga cagtttagat tacggttttt tcaccagtgc ttatggctgg
     8761 tttaatgtat tcctgctgat gctcatcttt ggtggtatca ttttggataa gatgggagta
     8821 cgcttcaccg gaatgggtgc ctgtttattg atggtgtttg gttgtggatt gaaatattat
     8881 gctattacta ctactttccc ggaaggtgcg atgcttttcg gattcaagat gcaagtcaca
     8941 ttggctgcat tgggttatgc catctttggt gtaggagtcg aaattgcggg tatcaccgtt
     9001 tcgaagatta tcgtgaagtg gtttaaaggc aaagagatgg ctctcgctat gggactggaa
     9061 atggcgaccg cgcgtattgg aacaactttg gccatggtgc ttaccgttcc tttggcagac
     9121 ttcttcgggt ctacggatga gagcggcgta ttccatacca atattcccgc tccgattctg
     9181 ttctgtctcg tcatgctgtg cgtaggtacc atcgcattct tcatctatac tttctatgat
     9241 aagaaactgg atgcttcact ggatgcggaa ggactggaac cggaagaacc tttccgcatg
     9301 aaagacatcg tatatatcat taccaacaaa ggattctggc tgatcgcatt actgtgcgta
     9361 ttgttctatt cggctgtatt ccccttcatc aagtatgcgg ctgatttgat ggtacagaag
     9421 tacaatgtag atccgaaact tgcgggaacg attcccggat tgctgccgat tggcgcgatc
     9481 atcctgacac cgttgttcgg gtcattgtat gaccgtatcg gtaagggagc cacgctgatg
     9541 gtgatcgggt cggtgatgct gattttcgta cacacgatgt tcgctcttcc tattctgaat
     9601 atatggtggt ttgcaacggt gatcatgatt attctgggat ttgctttctc attggttcct
     9661 tcggcaatgt ggccttcggt tccgaagatt attccggaga aacagttggg aacggcttat
     9721 gcgttgatct tttgggtaca gaactgggga ttgatgggcg tgcctttgct gatcggatgg
     9781 gtgttgaact cttattgcaa aggtccggtt gtagatggtg cacagactta tgattatacc
     9841 ctgccgatgg ctatttttgc tatgttcggt gtacttgccc tgattgttgc cttgatgctg
     9901 aaagcagaaa acaagaagaa aggctacgga ctggaagagg caaatattca gaaataatcc
     9961 agtatatatt ctatctgaaa agatataaaa gagaaaagat atggctacga aagagaaaat
    10021 aaacctcctg gaggtgatcc cttgtcgtaa cgaacatatt aaagctgaac aggaagggga
    10081 gactattgtg ctctccttcc ctcgttttaa acgttcgtgg atgagtcgtt atttattgcc
    10141 gaaaggaatg tccaaagata ttcatgtgcg tctggaagaa cacggtacgg ccgtatggaa
    10201 cctgatagac ggccagcgga cggttcgtga gattatagaa aaactcgcag accactttca
    10261 acatgaagca ggctacgagt ctcgtgtatc tacttatctt tcccaattac agaaagacgg
    10321 atttattaaa tggataatta tccattaaaa aagattgccc acaggaggac agcacatcct
    10381 atcagtacgc ccataatgat gagcgttccc catacgaaat agctgttatc tttttctttt
    10441 ttcttttccg aatccttgat gatgcgttcc atctcttccg gagtcgtatc cggcagaaga
    10501 taggggtcgt tgtttcttct aagtcgccct aacttgtcat ttctccgttc acggcgtaag
    10561 cgggaggctt ctttgccgtc tttcagccga cgtatcatgt cgagcatatg tccttcgcca
    10621 cccatcgttt tgttttttta gaggttttat ttgctttctt ctctatctac tttcagtagt
    10681 ccaccggtca ccggatcaaa gtaaactttg atggtcgagt tcttgttgaa taatactgga
    10741 gcaaggtatt ctatgatacc gaactgagta acaggtattt ctccttcata caatttcttt
    10801 ttgccgtccg tcagcgtcac cattgcctgt cccggtacgt tataagcaat gccttccatc
    10861 tctttcttct ttttcccgtc ctcttgcgga atcttcaccg ttttcaggtc tttcagactg
    10921 atgtagaatg gagtgcctgc caaatcgttg ttggcaacta tacccagctt ctttgaaaag
    10981 cggaaagcta cctcattgtc gaattcctta tccggagtga ggcggacagt aaatgtcttt
    11041 tcttctttat tgcggactcc cgaaaacatc tcggtcatgg cttcttcctg aagattcagg
    11101 ttgtcgagca tgattttgag ttgtgcgccg tccgaaggca tattatctgc ttgtccgcgc
    11161 aataatgcgt ttttactttc gcggatatta tagatttcct ttgctaccag ttcggccatc
    11221 ttggcggtag aacttgccat cagaatttct tctgtgagga agtcgcgggg attggctttt
    11281 cgttggggag caacggcatt gtttgctgca ttctttgcat tgttgctgct gtaggggacg
    11341 ttgattgatt tgataagacc ctcttctgtc agttccataa gaggagctac ggttttatct
    11401 ttcagtttga cgaaataagt agcttcgctg tttggtacac ctacaggttt cactttgaca
    11461 ctgttcagtt cccagtattc ttcgggttcg gcagagacgt tggtcagtct caggtagcgg
    11521 tcggcgtatt tgctgaattc acccggctta tagttgactt tgtttgcttt tatttctatt
    11581 tctatctggg ttttggggag ggcgtacact actccgtagt cttttcctcg tgtcactcct
    11641 gtcagcactt cggtctgcgc ataggcggaa gttgccatta gtagtcctgt tgctatgatt
    11701 aactttttca tattcggttc tttttagctg attttgaaaa acaaagttaa tgaagttatt
    11761 gaataaaccg taagttctta acttttattc gcttacaagt cgccatgccg tcggcagaca
    11821 ggtcacgata tcacttgcga ttaatccgat catgccctgt tttttctggg cgatgtctcc
    11881 ggccaatccg tgaatgtaag taccgatctt tgcggcatcc tcggcaggat agccttgcgc
    11941 aaggagtgca aggattactc ctgtcagtac atctccgctg cctcctgttg ccataccggg
    12001 attaccggtc tggttgaagt aacatttgcc ttcgggggtg ataatggcgg aataagctcc
    12061 cttcagaatg atatgtactt tggcagtgtg agccagttcg caggctttca tcagtcgttc
    12121 gtatgagtcc tgacatttgc cgaccagacg ttccagttct ttcgggtgag gggtgaggat
    12181 ggaacctttc ggcagatggg tgagcgtatg tcggtgattg gccagaatat tgagcgcgtc
    12241 ggcatccact acggtcggag tctgacaatg ttccagttgt tctatcaagg cagcttccgt
    12301 ttcctcgctg cgaccgagtc ccggaccgat gccgacagct tgataatcgt ccgtatcggt
    12361 aggtacggca aagcatgttt cgctgacatc tgtttctacc atggcttcgg gggcggacgt
    12421 ttgcagaata tcgttgttgc ataacggcgc gtgtacggtc agcagaccta ctcccgagcg
    12481 cagacaggca cgggcggcca gtaccgatgc acctgccatt cctttcgaac cggctatcag
    12541 cagggcatgt ccgaagtttc ctttatgggc gaattgctgg cgtggcttga tcagcgaacg
    12601 gatttcttcg atttccagca tttcgtagtt tgtttcagtc tcttcgattc cttcttcgct
    12661 cagctggatg tccaataatt cccattcgcc aacaaattct gtattttcgg caaagaggaa
    12721 ggccagttta ggaagttgca ggctgaaagt gacatccgca cggataatat tgctttttac
    12781 attgaatgta ttttcttctc ccatcagccc ggaagggatg tcgatggaga ctaccatggc
    12841 gggagaggca ttgatatatt tcacaacggc agcgaatcct ccgctcaatg gtttgttgag
    12901 tccggaaccg aataatccgt cgatcacgag atgctccgat gtcagtgtgg gaggtacgaa
    12961 ctgggtgctg atttcatgga aagttacttc ttccatcatc tctaccagtt ctttgttggt
    13021 ctggcagtcg ggcgaaagtt cgcctttcgt gttgaagaga tatacttcga tcttgtatcc
    13081 tttttccgcc atcatgcggg cgatggcgag ggcgtctccg ccattattgc ccggtccggc
    13141 aaagatggtg acaggtgttt ccggattcca tctgttggtg atggctttag tcagcgcctg
    13201 tgcggcacgt tccattaaat ctatggatgc aatcggttca tgttcaatgg tataggcatc
    13261 taacttctta atgctgctgc ttggaaatat tttcattgcg atattctttt agttttcgac
    13321 gcacaaactt acacaaaaac tctgaattaa tcctttattc cggttggttt tcggctttag
    13381 ataaagtggc aaattgaaaa atgcagggga aatcagaagt tatcttgggg tggctttgtc
    13441 ctgtctgtct gtgattcctc agttgggggg cggatatttc tctgcaaagg tacgggcatt
    13501 cttcagataa gatgcggaga cttttcggct aagatgcagg cattcttctc ttaaagtgcc
    13561 tcagggaaaa cgcattataa atcatgtaaa ataagttccc ataagaattc attatccc
//
