LOCUS       c00025_gnlPro..        16305 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BFPPJIBO_25.
ACCESSION   c00025_gnlPro..
VERSION     c00025_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 18:22:39
            Original ID  :: gnl|Prokka|BFPPJIBO_25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16305
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16305
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2753:6305](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2754..6305
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16305
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16305
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(181..1308)
                     /locus_tag="ctg25_1"
                     /transl_table=11
                     /translation="MAPASARQMASELALLPMWYAEEGSVVLAPSAYNLDYVKKIQELL
                     GLSVDLMTEPELASERNLDIRPWGWDIAIRKRLLDLGVEESELPSIEQLDKLRFCSHRS
                     CAVGLLPQLQLGACFCGESFYLTFPEEWKSFVESHDTCLLKAPLSGSGKGLNWCKGVYT
                     PSISGWCSRIGNQQGGVIGEPLYNKVEDFAMEFRSSGNGRFGFAGYSQFRTGGSGAYEG
                     NLLISDAAIERNLSEYIPVEEIYKLRDRLEQELSLRFGTIYNGYLGVDMMICRFPESPV
                     YRIHPCVEINLRMNMGVVARHIYDHYIYPTSTGAFQISYYPTEGTAWRAHKEMEEAYPL
                     EIEQGRIKSGYLSLVPAHKKSSYRAWVFISKSVFL"
     CDS             1543..2721
                     /locus_tag="ctg25_2"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPEWS
                     RELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREYLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANSLWKDHKVHKGD
                     KNVSFMVDEVMPFKICQEGAKIKNNLNVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             2754..6305
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_3"
                     /sec_met_domain="PFOR_II (E-value: 1.5e-18, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.7e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.7e-31, bitscore: 100.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.8e-12, bitscore:
                     38.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 6e-12, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 9.6e-09, bitscore: 26.0,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.8e-05, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 2.9e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNPENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKVFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKTKQHLVDIKSNVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKLFNQILEGDNAPAEAKEVLKAWIENMYDADKTKE
                     LAPQIEAIIEQGIAAGCPVSKELKGLTQYLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLW
                     RYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPTEAEELFKAAEENAK
                     WRYNSYKRLARENWGAE"
     CDS             complement(6458..7324)
                     /locus_tag="ctg25_4"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAMLLLASCTNSDLEKKKVKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFLG
                     EVYGEARVGLVVPQYVTIQSISELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWMVITGWTPHWMFDLFYLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRLLVDSW
                     IPKSENK"
     CDS             complement(7345..8169)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.9; E-value: 6.9e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg25_5"
                     /sec_met_domain="BPD_transp_1 (E-value: 3e-29, bitscore:
                     92.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMIHFSTFFDAVNAGIGSFIIGFQHILFGIP
                     FYITILVLAALAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSSRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             complement(8166..9392)
                     /locus_tag="ctg25_6"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGNEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTTGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSKQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETREFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             complement(9691..10029)
                     /locus_tag="ctg25_7"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVSTYGGIAALLGMSQ
                     CSRMVGRALKQIPDDLSAPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVPE"
     CDS             10125..11408
                     /locus_tag="ctg25_8"
                     /transl_table=11
                     /translation="LLYLQIIPTFVPIKSNPIINKTSTAVMKKKTILFASCLLGALAFS
                     SCEKNLYDESKQPEKEKKMTDLEVPADFDWKGSQNAKVKIASQSTATISVFLEENCNEE
                     ALMLRMDVDANTSKLELPIEIPAYIKNVYVKYGNGSEIQTVPVESNGTISIVVPANATA
                     LSRVTTRANKEVETNNIFNYPGYGNGTIMFEDMYPALGDYDFNDFVAWYNFQIDGFYWS
                     HNQCYAEYLMIGFQIRAIGGIYDYNLYIRLAEVQYNELDLEETQMYLERNNPEEAENIK
                     ILKGPKGELIISLKKPAIPNGYKYYNTEVNEKTKPKKMMAIYLVFNSPVNVKSLQDSKM
                     DFYIAKTNKGQEIHLKGYSPVYYNSNESYVNEDNFIWGLKVPASLHHAREEVNFLEAYP
                     DFEQWVTSGGQENQRWWNKPKTNKLIMN"
     CDS             complement(11550..14432)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 62.8; E-value: 1.2e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_9"
                     /sec_met_domain="Peripla_BP_1 (E-value: 5.2e-20, bitscore:
                     62.8, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAMKYMKWITVLFCLLGLAACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDKGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNYPDIKLIDKADAAWEREPAEVEMDSMLRRHPKIDAVYAHNDRI
                     APGAYQAAKKAGREKEMIFVGIDALPGKGNGLELVLDNVLDATFIYPTNGDKVMQLAMN
                     ILEKKSYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRSKNRLNKELSEQKKQVEQQRDKLEEQRDILEEQRD
                     KLEEQRDQLIQLSHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADSSLSEDQR
                     RMLLLVQRNVNILLRLVNQILDFRKYENGKMEYTPISLDILSSFEGWNESFMAAARKKH
                     IHFSFDYMPDTDYRTLADVEKLERIYFNLLSNAFKFTPENGKVTVRLSSLTKDDHCWIR
                     FTVANTGSMISAEHIRNIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTITVESDEKQG
                     TIFTVDLPVQTCETVVSENSPAFSVPATSVTSTDAATSAVAGAPVTPATSGYSGSSSLN
                     DALTYEEEELEKSYDSSKPCVLIIDDNADIRLYVHGLLHTDYTVIEAAYGSEGIRKAMK
                     YVPDLIISDVMMPGMDGIECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYI
                     SKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGD
                     SNLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGY
                     EVGFSSPSYFTKCYREQFGESPTDLLKRKG"
ORIGIN
        1 ttgagtaaac taacttaggt ataacaagcg aagttgtcaa ctaaatccag tacagtacac
       61 acatggcatg tgattacttg tttcatgcaa taaaactttt tgtttctcgg tgtggaacca
      121 atggtttcac tacatgaaac tatcagtttc acaccgagaa accataactt cgatataata
      181 tcacaaaaac acgctttttg agataaacac ccacgcccga taactactct ttttatgagc
      241 cggcaccaat gacaaatagc ctgattttat tcttccttgt tctatttcca aaggataagc
      301 ctcctccatt tctttgtgtg ctctccaggc tgttccttcc gtagggtaat agcttatttg
      361 aaaagctcct gttgaagtag gatagatata atggtcataa atatgacgcg ctactactcc
      421 catattcatc ctcaagttga tttccacgca aggatgaatc cgataaacag gagattctgg
      481 aaagcgacag atcatcatat ccactcccaa ataaccatta taaatggttc cgaaacggag
      541 ggataattct tgttcaaggc ggtcgcgcaa tttataaatt tcttcgacag ggatatattc
      601 cgaaagattc cgttcgatgg ctgcatctga aatcagcaga ttaccttcgt acgccccact
      661 tccacccgta cggaattgag agtatccggc aaaaccaaat cgaccattac ccgaagaacg
      721 aaattccata gcaaaatctt ccaccttatt atatagaggt tcgccaataa cacctccttg
      781 ctggttgcca atgcgtgagc accaaccgga aatggaagga gtatatacac ctttgcacca
      841 attcaaccct tttccgctac cggataaagg agctttcagt aaacaagtat catgtgattc
      901 tacaaatgac ttccattctt cgggaaacgt caggtaaaaa gactctccac aaaaacaggc
      961 tcccagttgt agctgtggta ataatcccac agcacaggaa cgatgggaac agaaacgcag
     1021 tttatccaat tgctcaatag aaggaagctc gctttcttcc actcccaaat ccaacagtcg
     1081 ttttcttatt gctatatccc agccccaagg acgaatatcc aaattccgct ccgaagcaag
     1141 ttcaggttct gtcatcaaat caaccgaaag tcctaataat tcctgtatct tcttcacata
     1201 gtcgagatta taagcggaag gagccaatac aacacttccc tcttctgcat accacatcgg
     1261 caacaaagcc aattcggatg ccatctgccg ggcggaagcc ggtgccatat agtttgtttc
     1321 accgctggct aacgccaaat catgttccgg attgaatata taaagagcct tttttgtcat
     1381 tttaaacgaa ttcaaaactt tattctgcaa atatatacag gaaatagtca ggaatggcta
     1441 caataaacag aaagttctaa ttaaactcac aattttgcca tctctacttt gcaaatccta
     1501 aaaaaagcag tatatttgcc acccgaaaaa caaagaactg aaatggaatc attctatcgc
     1561 acacacgcct acctcgttga gcacaccaat gcccccgttc gccgcgatct tatggacgag
     1621 atcgactgga gcgaccgcct gattggtatc aaagggacac gtggcgtagg aaaaaccact
     1681 ttccttctcc aatacgccaa agaaaaattt gggaacgacc gctcctgcct gttcatcaac
     1741 atgaacaact tctacttctc tggccacagc attgtagact ttgctaacga attccagaaa
     1801 cgtggtggaa aagtattgtt gatcgaccaa gtgttcaaac acccggaatg gagcagagag
     1861 ttgcgcatgt gttacgaccg ttttcctaat ttgaaaattg tctttaccgg ctcatctgta
     1921 atgcgactga aagaggaaaa tcttgaattg cgtgatattg caaaaagcta taacctgcgc
     1981 ggattttctt tccgcgaata cctgaactta caaacaggca tgaaattcag ggcctacagt
     2041 ctcgaagaaa ttcttagcac tcacgaacag attgccaaag gagtactctc taaagttcgt
     2101 ccgctggatt acttccagga ttacctgcat catgggttct atccattctt cctcgagaag
     2161 cgtaactttt cggagaattt gctgaaaacg atgaacatga tggtggaagt agatatcctg
     2221 ctcatcaaac aaattgaact gaaatatctt tcaaagataa aaaaattact atatttgctc
     2281 gctgtcgacg gaccgaaggc tcccaatgtg agtcaactgg caagcgacat acagacatct
     2341 cgcgccacgg tgatgaacta tatcaagtat ctggcagatg cgcgactcat taatctggtt
     2401 tatccgaaag gagaagaatt tcctaaaaaa ccttccaaga taatgatgca caactccaac
     2461 ctgatgtatt ccatctatcc tgtgaaagtg gaggagcagg atgtactcga cacattcttt
     2521 gcaaattctt tatggaaaga ccataaggta cataaaggag ataaaaacgt ctcttttatg
     2581 gtggacgaag taatgccgtt caaaatttgc caggaaggag caaagatcaa gaacaatctg
     2641 aatgtgacgt acgcgttgca taaggctgaa ataggtcggg gcaaccagat acctctctgg
     2701 atgttcggct ttttatatta aaagatttat ttacttaaat atttaattta gttatgacta
     2761 aacagaagaa attcatcact tgtgatggta accaggctgc agcgcatatc tcgtatatgt
     2821 tctctgaagt agctgctatc taccccatca ctccttcttc gactatggct gagtacgtag
     2881 acgaatgggc tgccgcagga cgtaagaaca tcttcggcga aacagtattg gtacaggaaa
     2941 tgcaatctga aggtggtgct gccggtgcag ttcacggttc tcttcaggct ggtgcgttga
     3001 ctactactta cactgcttct caggggcttc tcctgatgat ccctaatatg tacaaaattg
     3061 ccggtgagtt cttgccttgc gtattccatg tatctgctcg tacattggct tctcacgcat
     3121 tgtgtatctt cggtgaccac caagacgtaa tgtcagctcg tcagactggc tttgcgatgt
     3181 tggctgaagg ctctgtacag gaagttatgg atttggctgg tgttgctcac ttggctacca
     3241 tcaaatctcg cgttccgttc atgaacttct tcgatggttt ccgtacatct cacgaaatcc
     3301 agaagattga aatgttggaa aatgatgatc ttgctccgct gatcgatcag gaagctttgg
     3361 ctgaattccg tgcccgcgca ctgaatccga tgaatccggt tgctcgtggt atggctgaaa
     3421 accccgacca cttcttccaa catcgtgaat catgtaacaa ctactatgaa gcagttcctg
     3481 ctatcgtaga agaatacatg aatgaaattt ctaagattac aggtcgtaaa tacggtttgt
     3541 tcgattatta tggtgcagaa gatgcagaac gcgtaattat cgctatgggt tctgtaacag
     3601 aagctgcccg cgaagctatc gaccacttgg tagcaaatgg cgaaaaagtg ggtatggttg
     3661 ccgtacacct gtatcgtccg ttctctgcta aacacttcct ggctgctgta cctaagactg
     3721 ccaagactat cgcagttctt gaccgtacta aagaaccggg cgctaacggc gaacctcttt
     3781 accttgacgt taaagactgc ttctacggcg cagaaaatgc tccggttatc gttggcggtc
     3841 gctacggttt gggttcaaaa gatactactc ctgctcaaat tctttcagta ttcgaaaact
     3901 tggccatgcc aatgccgaag aatcacttca ctatcggtat cgtagacgac gttactttca
     3961 cttctcttcc tcaaaaagaa gaaatcgctt taggcggtga aggaatgttc gaagctaaat
     4021 tctacggttt gggtgctgac ggtacagtag gtgctaacaa gaactctgta aagattatcg
     4081 gtgacaacac tgacaaacac tgccaggctt acttctctta tgactctaag aagtcaggtg
     4141 gtttcacttg ttctcacttg cgtttcggtg atactccgat ccgttccact tatttggtaa
     4201 atactccgaa cttcgttgct tgtcacgttc aggcttacct gcacatgtac gatgtaactc
     4261 gtggtttgcg taagaacggt tctttcttgc tgaacactat ctgggaaggt gaagaactgg
     4321 ctaagaacct gcctaacaag gttaagaaat attttgcaca gaacaacatt tccgtatact
     4381 atatcaacgc aacacagatt gcattggaaa ttggtttggg taatcgtacc aacactatcc
     4441 ttcaatctgc attcttccgt atcacaggtg ttattcctgt agaccaggct gttgaacaga
     4501 tgaagaaatt catcgttaag tcttacggta agaagggtga agacgttgtt aacaagaact
     4561 atgctgccgt tgaccgtggt ggtgaataca agactttagc tgttgatcct gcttgggcta
     4621 acctgccgga tgatgcaaaa gctgaaaaca acgatcctgc attcatcaac gaagtagttc
     4681 gtccgatcaa tgcacaagat ggtgacttgc tgcctgtatc tgcattcaag ggtatcgaag
     4741 acggtacttg gtatcaaggt acttctaaat acgaaaaacg tggtgtagcc gcattcgttc
     4801 ctgaatggaa tccagaaaac tgtatccagt gtaacaagtg tgcatacgtt tgtcctcacg
     4861 cttctatccg tccgttcgta ctcgatgctg aagagcagaa gggtgctaag ttcgaacaat
     4921 tgaaagcagt aggtaaagta ttcgacggta tgacattccg tatccaggtt gacgttctcg
     4981 actgtctggg ttgcggtaac tgtgctgaca tctgtccggg taatccgaag aagggtggca
     5041 aagcattgac aatgaaacac ctcgaaagcc aattggctga agctgacaac tggacttact
     5101 gtgctgaaaa cgtgaagact aaacaacatc ttgttgatat caagtctaac gtgaagaact
     5161 cacagttcgc tactccgttg tttgagttct ctggtgcttg ctctggttgt ggtgaaactc
     5221 cgtatgtgaa attgatttct caattgttcg gtgaccgtga aatggttgct aacgctaccg
     5281 gatgttcttc tatctactct ggttcagttc cttctactcc gtatactacg aacgaaaacg
     5341 gtcacggtcc tgcttgggct aactcactgt tcgaagactt ctgtgaattc ggtctgggta
     5401 tggaattggc taacgaaaag atgcgtgctc gtatcgtgaa gttattcaac cagattttgg
     5461 aaggcgataa cgctcctgct gaagctaaag aagtattgaa ggcatggatt gaaaacatgt
     5521 acgatgctga caagacaaaa gaattggctc ctcaaatcga agctatcatc gaacaaggta
     5581 tcgctgccgg atgtcctgtt agcaaagaac tgaaaggtct gactcaatat cttgtaaaac
     5641 gcagccagtg gatcattggt ggtgacggtg cttcttacga tatcggttac ggtggtcttg
     5701 accatgtaat cgcttccggt aaggacgtta acattctcgt tctggatact gaagtttact
     5761 ctaacacagg tggtcagtct tctaaagcta ctccggtagg tgctatcgct aagttcgctg
     5821 ctgctggtaa gcgcgtacgt aagaaagacc tcggtctgat ggctactact tacggttatg
     5881 tatatgttgc acagatcgct atgggtgctg accaagctca aactctgaaa gctatccgtg
     5941 aagctgaagc atatccggga ccatctttga ttatcgctta cgctccatgt atcaaccacg
     6001 gtctgaaagc aggtatgggt aagagccagg aagaagaaga aaaagctgtt aagtgcggtt
     6061 actggcactt gtggcgttac aacccagctt tggaagaaga aggcaagaac ccattccaat
     6121 tggatagcaa agaaccgaac tgggaagatt tccaaggttt cttgaagggt gaagttcgtt
     6181 acgcttctgt aatgaaacaa tatcctactg aagctgaaga actgtttaaa gctgctgaag
     6241 aaaacgctaa atggcgttac aacagctaca aacgtttggc tagagaaaac tggggtgctg
     6301 aataatagta ataccctata aatataaagc ggtaatcttt gataagatta ccgctttttt
     6361 attgtatgaa ctctgtccaa cataaacagt actccctttt tcccactaga gttcatgtct
     6421 attttatatt taaaattaaa aataacaatg ctccaatcta tttattctct gacttcggaa
     6481 tccaactatc caccaacagc cgatgctcat ccctccattt gcgggctatt tcttcttcat
     6541 ccatccgggc atccttcata gctgtcataa aagagctaag ttcttctgtc gttagtttga
     6601 tgttgccaaa gaattcggca gcaaacggat ctttctcact gaatcctttc catgcaatag
     6661 catgtatttc ttccaagtct ccatatactt tcttcggatc atccaagaat ttcaaataaa
     6721 acaggtcaaa catccaatgt ggtgtccacc ccgtgatgac catccattct cctttatcca
     6781 tcgctttttt caaagaagcc agcatggtgg aactacttga agtcatgagg gtatacccat
     6841 caagtccgta agcagcaatg gccttatcgg tcgtcttcat tatccctgct cccgcatcaa
     6901 ttcctactat ttcagaagag aaacggtctt tattagcttc cagctcacta atagactgga
     6961 tcgtaacata ttgaggaaca actagtccta cacgggcctc tccatatacc tcacccagaa
     7021 attcgatact gtctccatac tgatccatat aatctttcat cgttattggt aaccatgcat
     7081 ccagaaacac atctgatttc tttcctgaca tagatacaaa aataggggca agatcagcat
     7141 tttgcaattc aacctcatat ccatgctctt ccaataccac cttagccaaa tgactcatgg
     7201 caataccttc cagccaattg gcataggcta tttttacttt ctttttctct aagtctgaat
     7261 tagtacagga agctagcaaa agcatagctg acaatactat tcctactatt ttatatattc
     7321 tcatacgtat tttatccttt ccgtttagtt cttatttttt cgtcctgcca ttccttgcgt
     7381 gatacggtct aagatgatag ctaaaataac aactgctata ccaccttcaa acccaagtcc
     7441 gattttcatt tgggtaatac ctttcaatac aatttctccc agaccaccgg cagcaatcat
     7501 ggcagcaatt acaaccatag aaagcgacat cattattgtc tggttgacac cagtcagaat
     7561 ggtgggcaac gccaaaggaa gctgcacttt atacaataac tgccaacggg tagctccgaa
     7621 cgaacgggaa gcttccacta catttttagg aacttgccgg attcccaatc cggtaaggcg
     7681 gaccacagga ggcatagcaa agataatggt ggcaaacact cctggcactg ctcccaatcc
     7741 gaaaaacaaa acagcaggaa tcagataaac aaaagcaggc atcgtctgca tcaagtcgag
     7801 aacaggacgg agtattttct ctgcacgcga actgtttgcc gtccatactc ctaaaggtac
     7861 accaacaatc agggccagac aggtagatga aaaaacgaga gctagagttt gcatggtagc
     7921 ctcccagaat cccattccat agatcagtaa taatcccaat gcggtgaaaa ttgccgtacc
     7981 gcgtcctgct ttcatccatg cgagtgcagc aagtaccaaa atggttatat aaaaaggtat
     8041 tccgaaaagt atgtgttgga atcctataat aaaactaccg atgcccgcat tcacggcatc
     8101 aaagaaagtg gaaaaatgta tcatcatcca attgatggcc atctctatat attgtcctat
     8161 atttatcata aatctattgc gttttgaatt atttcgttta tttcttcttt atctttcccg
     8221 gtcacttcga tgattaagga tgaaagcggg attgttccta aaaactcgcg cgtctcatca
     8281 atcacccata ccggcgaatt gctctttgtc attagaggaa gtatatcctc caacaccgta
     8341 tcctccaaca cagaatgtac ttctgtacgc acaatcgttt caatggattt ttcctgtttg
     8401 ctacgtaact taagcaagtc gttcagacgt acttctccga ccagtttatc atcggcgtct
     8461 atgacaggta atacggtgat attcttcgca cgcatcttac gaatcaatac ttcgggacct
     8521 tctttcttca gacgggccac caacggtttg tcaatcatta aagaagaggc ggtaataatt
     8581 ttgctcctat ccacgttttc aacaaaacgg gctacataat cgttagccgg ttcagtcagg
     8641 atttcctccg aagtacctac ctgcaccact tctccgtctt tcatgatggc aatacggtca
     8701 cctagcttaa ttgcttcact caagtcgtgg gtaataaaaa caatcgtctt tttcatcttt
     8761 gattgcaagg ccagtagttc atcctgcatc tgtacgcgaa tcagaggatc gagagcagag
     8821 aaagcctcat ccattaaaag cacttcagga ttattagcca gagcgcgagc cagtccgaca
     8881 cgctgttgca ttccaccgga aagctcgcct accatctgat tttcatatcc tttcaatccg
     8941 acaagcttca tgctttccat cgctttcttc tcacgttcct ctttcttcac tccctgaagt
     9001 tcgaggccga acgcgatatt gctcaatacg gaacggtgag gtaacagacc gaaattctgg
     9061 aaaaccatcg ccagctcttt ccgacgaacc tgcaataatt ctttttcgga aattttagat
     9121 atatctactc cgtttacaag cacttgcccg gtagtaggac gtatcagacg attgatacaa
     9181 cgcagtaatg tcgattttcc acttcccgag agtcccatta tcacgaaaaa ctctccttca
     9241 ttaattgaaa gattggcatc tttcactcct accgtacaac cggtatcttt cagaatttcc
     9301 tctttactct tatctttttt caacatcttg agggctttct gcttctcgtt accaaagata
     9361 aggtacaaat cctttatttc tattttactc atataatata ttggtttaga ttataatatt
     9421 tgttttgttt tcaactgccg cattccttat tctcacttac gataaacaag ttgaatgttc
     9481 gcatggttca gtcatgtcac atgataacat gacggtccga cgttttttaa atggttaaaa
     9541 aaaacagaca gagtagttta aaaggaatag aatttgataa gattatcctc ttaatgaaca
     9601 gtagaaaaca gtattttcat aaataaataa cagtctgttc ttgcatattg ttggcacaaa
     9661 ggtaaggaaa atagattaaa tatgcaaatt tcattcaggt acggagtaat tccaaagatg
     9721 ctttttcaag tctacgcatc cattttgttt gaaagagatc ccttcttcca acaagagttg
     9781 tttctgctct gtccaacccg gaacaagccg tcccgacgca ttgacaaccc gatgacaagg
     9841 cgcagataaa tcatccggaa tctgtttcaa agcacgcccc accatacggg aacattgaga
     9901 cattcccaat aatgcggcaa ttcccccata ggtagaaact ttacctaccg gaatttctcg
     9961 gacaacctga tacacctctt gacaaaagga tgcggaaagg ctcgccttat ctactttata
    10021 atctttcatc actcaaacat tactttattt cagttccaaa actagataaa aagaaaagaa
    10081 tttgcaaata ataaaagcat ttcaaataaa atatgcaact ttatttgctt tatttacaaa
    10141 taatcccgac ctttgtaccc attaaaagca accctattat taacaaaaca agcactgctg
    10201 ttatgaaaaa gaaaactatc ctgttcgctt cttgtttatt gggagcactg gctttcagct
    10261 cctgtgagaa gaacctttat gatgaaagta aacaacccga gaaagaaaag aagatgactg
    10321 acttggaagt acctgccgat ttcgactgga aaggttctca aaatgccaaa gtgaaaattg
    10381 ccagtcaatc aactgctact atttctgtat ttctagaaga aaattgcaat gaagaggctt
    10441 tgatgcttcg aatggatgtc gatgccaaca catcaaaatt ggaactccca attgaaattc
    10501 ctgcatatat aaaaaatgtg tatgtaaaat atggtaatgg ctctgaaata caaactgttc
    10561 ctgttgaaag taatggtact atttctatag tagtacctgc taacgctacg gcattatcca
    10621 gagttaccac aagagctaat aaagaagttg aaacgaacaa catcttcaat tatccgggat
    10681 atggcaacgg aactattatg ttcgaagata tgtatccagc tttaggcgat tatgatttta
    10741 atgattttgt tgcatggtat aatttccaaa ttgacggttt ttattggagt cacaatcaat
    10801 gttatgcaga atacttaatg ataggattcc aaatcagagc tataggaggt atatatgact
    10861 acaatcttta tatccgcttg gcagaagtac aatataatga acttgattta gaagaaactc
    10921 aaatgtatct tgagcgtaac aatcctgaag aggctgaaaa tatcaaaatc ctaaaaggcc
    10981 caaaagggga attgattatt tcactaaaga aaccggccat tcctaacgga tacaagtatt
    11041 ataatacgga ggtaaatgaa aaaacaaagc ctaaaaaaat gatggccatt tacttggtgt
    11101 tcaactcacc tgttaacgtt aaaagcctac aagacagtaa aatggacttt tatattgcaa
    11161 aaactaataa aggacaagaa atccacttaa aaggttatag cccggtttat tataacagca
    11221 acgaaagtta tgtaaatgaa gacaacttta tatggggatt aaaagtacct gcatctttac
    11281 atcatgccag agaagaagta aacttcttgg aagcatatcc agactttgaa caatgggtaa
    11341 catcgggagg tcaagagaac caaagatggt ggaataagcc aaaaacgaat aagttgatta
    11401 tgaattaata aatatacagt aaatcatata ctgaattaaa taagaggtaa ggtatgtcaa
    11461 tagatttcct tacctcttat ttttatcata tgaattccat agaagtataa acagataaat
    11521 gctcaccacc aaattttgca gattctatcc tatcctttcc tcttcaacaa atctgtcgga
    11581 ctctctccaa actgttctct ataacattta gtaaaataag aaggagaact aaaaccaact
    11641 tcataaccga tctctgccac tgtcatatcc gacgaggcaa gcagagaggc agctttcttc
    11701 aaacgagcta tacgaagcag ttcattcgga gaataattag tcagagattt aatcttgcgg
    11761 taaagttgca cacgacttaa tcccatatcc ttacccaaat cttctacatt caaatttgaa
    11821 tctcccatct ttgcctcaat cagagctttg aatttttcca caaagtcttt atccatatca
    11881 cagacatcct ctttcgccaa cgtttgtccg tcaccaaaaa actgtttcag gcggcggtgt
    11941 gaatctatca gattacgaac gcgtgccaat agtaattgcg aactgaaagg cttggagata
    12001 taagaatctg caccaccatc atacccttga attcgttgtt catccaaaga acaagctgtc
    12061 aataggataa caggaatatg acaggtttgt aattcgcttt tcaagcgacg acaacattca
    12121 attccatcca ttccgggcat cattacatcg gagataatca agtccgggac atatttcata
    12181 gctttacgaa taccttccga gccgtatgca gcttctataa cagtataatc agtgtgaagc
    12241 aatccatgca catataagcg aatatcagcg ttatcatcaa taatcagaac gcaaggtttg
    12301 gaagagtcgt aacttttttc caattcctct tcttcgtaag ttaaagcatc attcaagctc
    12361 gaagaaccgg aataaccaga agttgcagga gttacgggag ccccagcaac ggcagaggtt
    12421 gcagcatcgg tagaggttac agaagtagca ggcacagaga atgccggaga gttttctgaa
    12481 acaacagtct cgcaagtctg tacaggcaaa tcaacggtaa agatagttcc ttgcttttca
    12541 tcactttcca ccgtgatggt acctttatgc aattccacaa aagcctttac caatgccagt
    12601 ccaatacccg aaccggcatg gtgcatatct atcttataga aacggtcgaa aatattccgg
    12661 atatgctccg cagaaatcat tgagccggta ttggcaacag taaagcgaat ccaacaatga
    12721 tcgtctttag tcagggaaga taagcgtaca gttacttttc cattctctgg agtaaatttg
    12781 aaagcgttgg aaaggaggtt gaaatagatg cgttccaact tttctacatc tgccaatgtg
    12841 cggtaatccg tatccggcat ataatcgaat gagaaatgaa tatgtttctt ccgggctgct
    12901 gccatgaaag actcgttcca tccctcaaaa gaagaaagaa tgtctaacga aataggagta
    12961 tattccattt ttccattctc gtatttacga aaatccagaa tctgattgac aagacgcaag
    13021 aggatattca cgtttcgctg aactaacaat aacattcggc gctgatcttc actcaaagac
    13081 gaatcagcca gtaaatgctc taccgggtcg gcaactaatg tcagtggagt acgaaaatcg
    13141 tgagatatat ttgtgaagaa aaccagcttg gcatgagtcg cttcttccag ttgatgagaa
    13201 agctggataa gctgatcccg ctgttcttcg agtttgtcac gctgttcttc aagaatatcc
    13261 cgttgctctt cgagtttatc gcgctgttgc tctacttgtt tcttctgttc ggacaactct
    13321 ttattcaggc gattcttgga acggagggat ttatagacta ccaacaacaa tcccgctact
    13381 aataaaagaa taaccaagcc gccatacatc acgacctgct gcgtagctac acgcgacaga
    13441 tacccaccga tacgtccgtt caatgtttca atcttctgat ccagttccga gatatgggta
    13501 gtctgaagtt gcataacgtg cgcgttcgtg cggtctacaa cggcagtatt catgaccgtt
    13561 tcgcgaggat aagacttctt ctcaagaata ttcatggcca gttgcatcac tttgtcccca
    13621 ttagtcggat aaataaaagt tgcatccagc acattgtcaa gcaccaattc aagcccgttt
    13681 cctttgccgg gcagggcatc aatgccaaca aaaatcattt ccttttcacg tccggctttc
    13741 ttcgcagctt gataggctcc cggagcgata cggtcgttat gtgcatatac cgcatcaatc
    13801 ttcggatgac ggcgaagcat actatccatt tccacttctg ccggttcacg ttcccaggca
    13861 gcatccgctt tatcaatcag tttgatatcc ggataattgc tgatagcagc cataaatccc
    13921 tgatggcgtt ccatggcagg ggtggaacca cccagtccgg taagctccac tacattccct
    13981 ttccctttca gacttgatgc gatataattt cctaccgcac gacctatttc ataattatcg
    14041 gcaccgatat aggcagtata tttatcagaa agtatcttcc ggtctacaag aatgacaggt
    14101 attcctttct gataggcctc ctccacaatt ggagtcatgg gagccgcttc attggcggaa
    14161 attatcagta aatcaactcc tttatctata aaataatgaa catcttccgc ctgcttacgg
    14221 ttatcatccg ccgccgagcg gatttcaacc gacactccat cataaaacat cgcttcgcga
    14281 agaatctcat cattcatctt gtgccgccaa gagtcatcac tacattgggc caccccaata
    14341 cggaaacgag gcgcatcctg acgacaggcc gccaagccca aaagacaaaa caagactgtt
    14401 atccacttca tatatttcat cgcttcaatc attccctttc tttcgtatat cttttgtatt
    14461 tctttctgta atccaaattt ctctccccgc attatttgca ttcaccaccg ggaaatacat
    14521 cagttccact ttcacagggt tcagcgtgta ttttccagta aagcgtgaaa gcaaaggaac
    14581 cgtaaactga taagtaccta ccggtaattt ttcgctaaag ataacagttt tctctttaaa
    14641 atactcacga tatacttcag aacgggagaa attaacaggt tttgaggcat aactacaacc
    14701 tgccggaaca ggaacttcga gcatcacata ttgcgcaccc tcctgtttca cctgcaaggt
    14761 aactgtcaat gtaacaggta cacccgccac caaagagtct ttttccaaag tcgcctccac
    14821 cttgaaagca tcactctgac gagcattcat cacacgcttc attgaataga cactatacaa
    14881 taaaggctct tttcccgttt ttgaaataag cagactgtcg cctgctatca gccgggcatg
    14941 ataaggaaat tccgtaattc gttgatgatc cttaccgctc acagacaccg acgttcctga
    15001 catccctccg gaacctgcca gcaaatcggt cagaacagtt gccacagccg aagaagcctg
    15061 atacgtattc catccgcgct ccttagtccg caaaatatac aattgcatat tttctttcaa
    15121 cttacacagg gaagggtcat ttttaataat ccggtaggct atcaatgtat ttatcatctg
    15181 atttccctcc caataataag tacgccgtcc gtcgtcacag taaacacctt ccagcatatc
    15241 ctttttcaga taaggacgta cgctatcacc cacattcacc gaatccacct gttgcttgat
    15301 ttcccagaga agcagcttct ctttcaagta tgaaagagga cgataatact tgtttctatt
    15361 tgccaacgag tcttctttct gttccaattg ccggacgaaa ggttccaata atctgactgc
    15421 cgaagaataa tccgcctcta ctttccactc atgcagagca tgaagtattt ctatatcttc
    15481 cagtttcatt cctcgataag gacgcgtatg agcatactcc actttcaaac cattcagatt
    15541 caactccaca ggataacctg catcttgcgc catcttcaaa gcccgcagaa tatgcgcaga
    15601 catccagaaa gaagtatttt cagagttccc ccaccacgac cataactgat gtttgttctg
    15661 atgattcgtc agtcgatgga tgataggtcg aattgcttta tctactttca ccttttcacc
    15721 cttactctgc atatactgtt ggtaagccaa caaaccgatt aacttggatg ccagctgctc
    15781 attgcacaaa tatttgtatc ctgtcaagta attcactgat tctttataga tgtccaactg
    15841 attgtcagtg atactcacca tcacttcttc atcctcgccg gattgcactt tgaccgtctt
    15901 tgcatcggac agaataccca atgtgccctc cgccaattca gttccctgtg gcagtatcgg
    15961 aatcgtatat tcctctccat cctgatagcc atcgtcgcga gtgaaaagat agctgatggt
    16021 cacgctatcg gcatgaactg cctgcatcgg cactgtttca tgaaatccct ccatgaaact
    16081 cacttcctgc cgtttcaacg tatccgttcc gacgcagaac tgtgtctttc cggctatgtg
    16141 ctgcccatcc agataattgc ggatagtccc aaccaccgta ctctgatccc cctccaccag
    16201 gaagcgggga gttttcaact ccgccatcaa cggtttgtaa gagcggatgg aacgtcggaa
    16261 agtacccgtc tgcaaacgac ggttcatgcc ataaacgaca gtttc
//
