LOCUS       gnlProkkaIBOLCLPD_113  15307 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IBOLCLPD_113.
ACCESSION   gnlProkkaIBOLCLPD_113
VERSION     gnlProkkaIBOLCLPD_113
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 16:28:21
            Original ID  :: gnl|Prokka|IBOLCLPD_113
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 9934
            Orig. end    :: 25241
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15307
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12302]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12302
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..15307
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15307
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             complement(1496..1801)
                     /locus_tag="ctg113_11"
                     /transl_table=11
                     /translation="MSHNHDHNHDHEVITLVDEQGNETLFEILLTIDGREEFGKNYVLL
                     VPAGAEEDADGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFIDEN"
     CDS             complement(1910..2329)
                     /locus_tag="ctg113_12"
                     /transl_table=11
                     /translation="MRVMGLDVGSKTVGVAISDPLGFTAQGVEIIKINEEDKEFGFDRL
                     GELVKEYQVDKFVIGLPKNMNNTEGPRVEASKAYGDKIKEIFNLPVDYQDERLTTVQAE
                     RMLVEQADVSRGKRKKVIDKLAAQLILQNYLDRMF"
     CDS             complement(2329..2595)
                     /locus_tag="ctg113_13"
                     /transl_table=11
                     /translation="MGFTDETVLFNLNDGDKDEISNTLTNVYRSLAEKGYNPINQIVGY
                     VLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLKGNGTDL"
     CDS             complement(2722..2910)
                     /locus_tag="ctg113_14"
                     /transl_table=11
                     /translation="MTKVCYFTGRKTVSGNNRSHAMNKTKRVFKPNLQKVTVLIDGKPK
                     KVWASARALKSGKVERV"
     CDS             3080..4348
                     /locus_tag="ctg113_15"
                     /transl_table=11
                     /translation="MPDNLALRMRPRSISEVIGQKHLVGEGKIIRRMVEANMLSSMILY
                     GPPGIGKTSIASAIAGTTKFAFRTFNATVDSKKRLQEIAEEAKFSGGLVLLLDEIHRLD
                     KAKQDFLLPLLENGNIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKEAILNVL
                     GDKERGFAFEVHLDDDALDFIATATNGDLRSAYNSLDLAVMSTPASGNGQHHITLDIVE
                     NSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLARRLTVI
                     AYEDIGLANPDAQVHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYKAMDAVL
                     ADLRKSGNLPIPRHLRDGHYAGSKALGNAQDYKYPHAYPEKWVKQQYLPDKLRGVNYFQ
                     PNETGKYERALGANKERIDKLSR"
     CDS             complement(4790..5929)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 86.3; E-value: 5.3e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg113_16"
                     /transl_table=11
                     /translation="MASVRYRKRGDSNLWTYEIRNEGKTVAHNSGFKTKKLAESEAEPI
                     LQELRLGKRISRDISLADLYQEWLELKILPSSRSEETKKKYLLRKNTIERLFGNKKVTQ
                     IRASEYQRIMNKYGQTVGRNFLGRLNTGIHQSIQMAIADKVLIDDFTQHVELFSSKEQQ
                     MTEEKYLHTEKDYLDLLLAVKRKFDYQRSIVPYIVYFLLKTGMRFGELVALTWNEVDFD
                     RGLLKTYRRYNTLSHKFVPPKNKTSIRMVPIDEECIKILRLLQTEQERANMELGIKNRY
                     RMIFQHFGYIHSVPDIASVNKALSVLLNELDIYPIITTKGARHTYGSYLWHKGFDLGVI
                     AKILGHRDISMLVEVYGHTLEEKIFEEFNQIRDIWKDCS"
     CDS             complement(5931..6119)
                     /locus_tag="ctg113_17"
                     /transl_table=11
                     /translation="MDNNLISNKELIEMGYRPHTANDIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVNEILGTEVA"
     CDS             complement(6131..7105)
                     /locus_tag="ctg113_18"
                     /transl_table=11
                     /translation="MVSIQDLRSIQERCEIGELVQRLDVSIDRLTVIWDTDTGSLRRIF
                     KNLKQAISTRVDSFEIHDNVRDDVFTLAKDFNEYDSINIIFFQLSTYGGEQLIRIDFNP
                     NTLKEFDGMKVWRQLMYFARLNSLTVRLSRFDLTFDIFNRPEIVNLQHIKGGVTHKVFY
                     GRGGELETKYWGSSGSNVQVRLYDKNKEIIAHKREEKLDLGVNPFWWRLEFQLRTKAIG
                     EDMVQDIMNRLDNFGFYKLEHIRVDQRAFTIIFLSNPELLSLAFPNLKSDSIKKKKTRV
                     RKLLREETNQFAEELKEVLIQNLPKLNTELQLLVGEFLTLENQ"
     CDS             7551..8063
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 59.3; E-value: 1e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg113_19"
                     /transl_table=11
                     /translation="MTFIIQNFGPNLARLRIEKGVSQTQLAEDLGIGKQSISDYEKQKS
                     YPTFANLDKIAEYFNATPTQLFGTSKEIELEKSVLESNEYSDKVSEILKAVKYIENFLE
                     TDGQYLEDLLYLTRGKQLYTEDGDELYTDPTSQKRTFHNQYEPGFIVARDKSPLELLIE
                     NKELFDK"
     CDS             complement(8467..9039)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 143.6; E-value:
                     1.3e-43)"
                     /gene_kind="transport"
                     /locus_tag="ctg113_20"
                     /transl_table=11
                     /translation="MEKDGETILAPCDLTIHAGEKIAIIGESGAGKTTLLNILYGEIHP
                     SQGQIRYQGRELTSCQLYQAGAYILQSSHVFDDLSVEENIALGQEIDQQRMDNILQETG
                     LLSLKGKVPSNQTLSGGEKQRLEIARALYHKRQFILADEVKANLDAKNQEKINQLLFSL
                     PQAVVEVIHHYTKEDLKRYDKVIHLKK"
     CDS             9073..9318
                     /locus_tag="ctg113_21"
                     /transl_table=11
                     /translation="MVKYAVSSQLISKQVLILIAEGLGRLAGIDKVGQFLKLVADVVGD
                     QINADKTSRRKVVLVGHESANHNGRHRAKCIYTVDK"
     CDS             complement(10001..11200)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg113_22"
                     /sec_met_domain="PF04055 (E-value: 4.1e-16, bitscore: 50.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.3e-14, bitscore: 44.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKTIETDIGTYYFDSVNFTLSLSPISKQSSPTLDSVEDGVLKKV
                     VINISNSCNLSCSYCYADGGNYGMDNRIMDLTTADNIIQEIASKGVTQINRLILFGGEP
                     FLNIELFIYFIEKLSTLLNVVKIETVTNGTVLNKRVKEMLVKFHPYLTISLDGPEIVHD
                     RLRGRGSHRKTLRFINYLKNIDYENFEIASTYTRLHQKNGLSREDIFQYFTDMDVHFNI
                     NDVFTKNKVLIVKEMEKSLAERKQFIDKSIQHVINNNEKAFISPILYDVLISMIYKSTN
                     RTFCDDIDPSNTLTYDVDGSKKLCFRFWGTHNSPKAESFNNKDNFEKCKNCWCRGMCLE
                     CVANVIDGYSSVISEDGEFLECSKPELMEYCIKQIIYLSKDREKLSRLVNNFRGFIRYA
                     "
     CDS             complement(11442..12302)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg113_23"
                     /sec_met_domain="TIGR01716 (E-value: 2.8e-49, bitscore:
                     158.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYGKIFKKFRESRGLSLKNVAKSGLSSSHLSRFENDEADLTISK
                     FFLALDAIHMPIEEFVYAVRDFRRDDFNELLEKIRYLVSNRDIDGMKKLLISQMEKKDK
                     KEPFASFNTILIKIRLQDLSGETYVTDQEIVTISDYLFSAEYWGYYELLLFMNTIDAFN
                     RNTMMILAKEMCHRSDFYRDIPNNRRLLATMLLNAYITCIERNEWMDALYFEKQLKYCN
                     FSETEMYEKLVLHYANNLYDLKKNNNRHAVLEMRKCIAATKLVDSNQIAIKFENYLQKV
                     LDDMR"
     CDS             complement(13152..13376)
                     /locus_tag="ctg113_24"
                     /transl_table=11
                     /translation="MIEITYLDSAKQERVVRFNSYDEFEQSQHACLIGVADYYPVQKLT
                     YNGYDLDYHGTYGDIFFFLMKQDLSQYKK"
     CDS             complement(13468..14253)
                     /NRPS_PKS="Domain: PKS_KR (8-164). E-value: 2e-13. Score:
                     42.5. Matches aSDomain: nrpspksdomains_ctg113_25_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     218.8; E-value: 1.4e-66)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg113_25"
                     /sec_met_domain="adh_short (E-value: 3e-37, bitscore:
                     119.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 8.7e-32, bitscore:
                     101.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKELEGKTAVVTGGSKGIGTAIAKRFGTEHMNVVVNYFSDSKGA
                     EEAVRIIEEAGGKGVAVQANIGEESGVKKLLDQALEFFGSIDVWVNNAGVENRSATHEL
                     SLDDWNRIIKTNLTGVFLGSKVALQYFTDNERKGNIINMSSVHEQIPWPGFANYAASKG
                     GVKLFTETIAMEYGKRNIRVNNIGPGAINTPINSDKFLDPLQYEETARMVPMHRIGKPE
                     EVAAAAAWLASDESSYVTGITLFVDGGMTLYPAFQDGKG"
     aSDomain        complement(13762..14229)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg113_25_PKS_KR.1"
                     /evalue="2.00E-13"
                     /label="ctg113_25_PKS_KR.1"
                     /locus_tag="ctg113_25"
                     /protein_end="164"
                     /protein_start="8"
                     /score="42.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TAVVTGGSKGIGTAIAKRFGTEHMNVVVNYFSDSKGAEEAVRIIE
                     EAGGKGVAVQANIGEESGVKKLLDQALEFFGSIDVWVNNAGVENRSATHELSLDDWNRI
                     IKTNLTGVFLGSKVALQYFTDNERKGNIINMSSVHEQIPWPGFANYAASKGG"
     CDS_motif       complement(14179..14223)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg113_25_0001"
                     /evalue="2.50E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg113_25"
                     /protein_end="25"
                     /protein_start="10"
                     /score="10.5"
                     /tool="antismash"
                     /translation="VVTGGSKGIGTAIAK"
     CDS             14869..15189
                     /locus_tag="ctg113_26"
                     /transl_table=11
                     /translation="MLKIAIIGYSGSGKSTLASFLGQHYSSEVLHLDKIHFTSNWQERT
                     VNEMTDNISKFMSQKGWIIEGNYSTCLYEKRMREADCIIYFNFNRFNCLYRAFRRYLRY
                     KG"
ORIGIN
        1 aaggcaaatg caaaaacgac tataggtaag aaataattac ggctaaggaa gataccaaaa
       61 acttttagcg tgcggatttg gttatcatta cgacgtcggt gagaggttcg ctccgctctc
      121 tttttaatag catcatccag agaaagtgca gtcaagacta aaccatatgg gacgatggta
      181 agaatgctgt aaagtccaaa actttgagag aatagactgt aaactagtgt aaagataaag
      241 ctaaggatta atacccattt aatgctttta tctttagcat caccaaggag gtggttacct
      301 gtagtaacta caccaataag gagtccagaa cctataacag caaaactttg gtaagccaat
      361 gtcagtagga agttattttt ttctacagcg agttgtgtaa agttgtaaac tagaacttga
      421 ttaatatagt ccgaagtgat ttgcaagttt aggatgaaat aaaggcatag gtacagtact
      481 aaaatattac caaaaataat acaaaggact tgataaaaac cacgagcaaa gtgcttgttg
      541 acaagattgt aaacaaatat tgtcacaagt gacaataccc agaaaataag agttcgagct
      601 tcaaagagtg ctccagcagc accagcaaaa ccgtaaagaa taaaggcttc atcacgactg
      661 tgaccagcaa agtaccgggt taagaagaaa atagcaccga ggacaaaagg catggcaaat
      721 tggataggat agagtccacc aaaaccaagt gtcccattaa ttaaaaagaa aataatacta
      781 attagagttg caatttcctt cttatttgtc atatgcatga caaccttgta aaggtagctg
      841 ccagaaagat agtaggttag aaactgtatt ggaattaacc aaagagtaga ccccagacga
      901 aaagctagag aaattaggaa ataatagaag aacccacctg tcgcaaaaaa gtcagaatag
      961 ggtaaactac cgttggcaaa catttttgca atgtaaaggt tttgggattg tatattattg
     1021 gaaaagtctg taaagcaagg gactgatata ctacatgcac tcaaaatcag actgaggata
     1081 aggatatgtg ctttatgctt acaaggaagt gaaatcttag tttttttttc tttctgataa
     1141 gaagttgatt cttttgtacg cccttgaatt gttacttcac ccttttcaga ttgcttatca
     1201 tgtgtatgag attgatgggg gcttcgatga taaccttgat agctacctga tcctaggata
     1261 ttgtctttgt tatatggact caaattaaac tcctttgctg tcattttgaa agttacaaat
     1321 aagggaaaaa cccaaaatct cttatttaaa gtatatcaga taataccatt tagtcaattt
     1381 ctctcttatt tcttacattt aagaaaaaac cttctaaaaa agagactgaa ataaactatt
     1441 tcagtctctt ttttagaagt aaatgattag gcttagttac gcccaatatt attttttagt
     1501 tttcatcgat aaagctattg aaaacttctt caatcatatc ccattcagca tctgaatctt
     1561 caggaattgg ttgaaggtcg ccttcagtgc cgtcctcatt ttcagtgaat gagtatgcct
     1621 ggatttcgat ttctccatct gcatcttctt cagcaccagc tggaaccaaa agaacgtagt
     1681 tcttaccgaa ttcttcacgt ccatcaatcg ttaataagat ttcaaaaagt gtttcattcc
     1741 cttgttcgtc tactaaagtg atgacttcat ggtcatggtt gtgatcgtga ttgtgtgaca
     1801 tattgttctc ctttttgaag agagtactca atagtgagga gaatctagaa gttctgattg
     1861 gtagtttact agattgtcgc tcgactaatc ggtctctatt tacagtttat taaaacattc
     1921 gatcgaggta gttttgcaga ataagttgag cagccaattt atcaataact tttttacgct
     1981 taccacggct gacatctgct tgttcaacta acatacgttc tgcctgaaca gttgtcaatc
     2041 gctcgtcttg gtaatctaca ggaaggttaa agatttcctt aattttatca ccataagctt
     2101 tgctagcctc aacacgtggt ccttcagtgt tattcatatt tttagggaga ccaatgacaa
     2161 atttatctac ctgatattct ttaacgagtt cacctagacg gtcgaagcca aactctttat
     2221 cttcctcgtt aattttgata atttcaacgc cttgggccgt aaaaccaagt gggtcactaa
     2281 tagcaacacc cactgttttt gagccaacat caagtcccat tactcgcatt acaggtcagt
     2341 tccatttcct ttaagataat agcgaacgag ttcttcaacg atttcatcac gttcgtattt
     2401 gcgaatttgg ttacgggcat cattgtaacg cggaacataa gcagggtcac cgctcagaac
     2461 ataaccaacg atttggttga taggattata acctttctca gccaacgaac ggtagacatt
     2521 tgtcaaagta ttactgattt catctttatc accgtcgttt aggttgaaaa gaacagtttc
     2581 atctgtaaat cccatactga caccttcttt ctataaggat tatctattag ttccttatta
     2641 taacataagt atacccaaaa gtgaaagacg atgaacacta aaagagatga ctgatgtcat
     2701 ctctcttaat gtctaataag attaaacgcg ttcaacttta ccagatttaa gtgcacgagc
     2761 tgaagcccaa acttttttag gtttaccgtc gataagaaca gtaacttttt gaaggttagg
     2821 cttaaagaca cgtttagttt tgttcatagc gtgtgaacgg ttgtttccag aaacagtttt
     2881 acgtcctgta aagtaacata ctttagtcat ttcgtgtttt cctcctaggt agaatttatt
     2941 acggatgtgc tagcaccaca taccaaaata ttctatcata agaatttagg tttgacaaga
     3001 actatttata atttcttttt acagaaaaat agtatattct tattataaga agaataaata
     3061 gttaaaaaaa ggagagaaga tgccagataa tcttgcctta cgcatgcgtc cacgttcaat
     3121 ttcagaggtg attggtcaga aacatttagt tggtgaaggt aaaattattc gccgtatggt
     3181 agaggcgaat atgctgtcgt caatgattct ctacggacct ccaggaatcg ggaaaacctc
     3241 gatagccagt gctattgcag gaacaacaaa atttgctttt agaactttta atgccactgt
     3301 cgatagcaaa aaacgtctac aggaaattgc agaagaggct aaattttcag gtggtttagt
     3361 tctacttcta gatgagatcc atcgtttgga taaagcgaaa caagattttt tgttaccatt
     3421 attagagaac ggaaatatta tcatgattgg tgccacaacc gagaatccgt ttttttctgt
     3481 aacaccagcc atccgtagcc gtgtacaaat atttgagttg gaaccactct ctaatgaaga
     3541 tatcaaggaa gctattttga atgttctagg ggacaaggag cgtggcttcg cctttgaggt
     3601 tcacttagat gatgatgctc tagattttat tgcgacagct actaatggtg atttacgatc
     3661 ggcatataat tctttggatc tggctgtcat gtcgacacca gcttcaggaa atgggcagca
     3721 tcatattact ttagacatag tggaaaatag cttacaacgc agttatatta ctatggataa
     3781 agacggtgat gggcactatg atgtcctttc tgccttgcaa aaatctattc gaggatctga
     3841 tgttaatgcc agtcttcact atgcggcacg tttggttgag gcaggggatt tgcctagtct
     3901 agcacgtcgc ttgactgtga ttgcctatga ggatattggt ttagctaatc cagatgcaca
     3961 agttcacacg gtcacagcct tggaagctgc acagaaaata ggttttccgg aggcacgtat
     4021 tttgattgcc aacgtagtta ttgacttagc attatcacct aagtcgaatt cggcttataa
     4081 ggcaatggat gctgtcctgg cggatcttag aaagtctggg aatttaccta ttccgcgtca
     4141 tctgagagat ggacactatg ctggaagtaa ggcactgggt aatgcacaag attataagta
     4201 tccacatgcc tatcctgaaa agtgggttaa gcaacaatac cttccagata aattaagagg
     4261 agtcaattat ttccaaccta atgaaactgg gaaatacgaa agagctcttg gagctaataa
     4321 agaacgaatc gataagttat ctagataata cgagaagaat caacgaaaac gattgcaaaa
     4381 aaaatgattt ttcctcttgc aataattttc aaaagtggta ttataaaaac atagaaattg
     4441 ctgtggtata cgaatccaca tataagtgtt gaccgactaa tttttgtatt atcgggagac
     4501 agaggtctat taacagtgtg caggctggct cacccagaag caactgaagt tagtagcgag
     4561 tcgcccacct gcttttttac gtcgcgggtt caatacaaac tgtggatcat cggtaccaat
     4621 acagcatcca gcctccttag ctcagttggt agagcagtgg actcttaatc catgggtcac
     4681 aggttcgagc cctgtagggg gcatcaaact tcaacagtaa aagccttgat aaccaaggct
     4741 tttttgcttg tcttaagagc atttgcccca tcgtttgccc cacatttttt tatgagcaat
     4801 ctttccagat atctctgatt tgattaaatt cctcaaaaat tttctcttct aaagtgtgtc
     4861 catatacttc taccaacatt gaaatatctc tatgccctag aatttttgca ataactccaa
     4921 ggtcaaaccc tttgtgccag aggtagcttc cataggtgtg acgtgctcct tttgtcgtga
     4981 taattggata aatgtccaac tcatttaaga gaacactcaa agctttattg acgcttgcaa
     5041 tatctggaac tgaatgaata tatccaaaat gttgaaagat cattcgatat cgatttttga
     5101 ttcctaactc catgtttgct ctttcttgct ccgtttgtaa aaggcgcaaa attttgatac
     5161 actcttcgtc tattggaacc atccgaatag acgttttatt ttttggtgga acaaacttat
     5221 gagagagagt attatacctc ctgtatgttt ttaacaatcc tctgtcaaaa tcaacctcat
     5281 tccaagttaa cgctactaac tctccaaacc tcatgcctgt ttttaataga aaatagacga
     5341 tataaggaac aattgaacgt tggtaatcga attttctctt tactgctaaa agtaaatcca
     5401 gatagtcctt ttctgtatgt aaatatttct cttctgtcat ctgttgttct ttggatgaaa
     5461 acaactcgac atgttgtgta aaatcatcta ttagaacttt gtcagcaatt gccatttgga
     5521 tgctctgatg aatccccgta ttcaatctac caagaaaatt tctaccaact gtttgcccat
     5581 acttattcat aattctttgg tattcactcg cacgaatttg agtgactttt ttatttccaa
     5641 ataatctttc aattgtgttt ttacggagaa gatatttttt ctttgtttct tccgacctac
     5701 tacttggtaa aatttttagt tcaagccatt cttgatatag atcggcaaga gaaatatctc
     5761 tagaaattct ttttcctaaa cgaagttctt gcagaatcgg ttcagcttct gactctgcaa
     5821 gtttttttgt tttaaaaccg ctattatgag caacagtttt tccttcgtta cgaatttcat
     5881 aggtccataa attactatct cctcgctttc ggtaacgaac acttgccata ttacgccacc
     5941 tctgttccta gaatctcatt tacaacactt tttggaacaa ccatcaaacg tttgcgatta
     6001 taaaatgtat agcctcgtga tacaagtaat tctcttgcct gatggatgat atcatttgca
     6061 gtgtgagggc gatagcccat ttcaattaat tctttgttgc taattaaatt attatccata
     6121 gttatcctcc ttattgattt tctaaagtca gaaactcacc tacaagtagt tgtaattctg
     6181 tatttaattt agggagattc tgtattaata cttcttttaa ttcttccgca aattgattcg
     6241 tttcttctct caatagtttg cggactcttg tttttttctt tttgatgctg tctgatttta
     6301 aatttggaaa agctaatgat aacagttcag gattgcttag aaagataatt gtaaaggctc
     6361 tttgatccac tcgaatatgt tctagcttat aaaatccgaa attatcaagt cgattcataa
     6421 tatcttgcac catatcctcc ccaatcgctt tagttctgag ttggaactct agtctccacc
     6481 aaaacggatt tacacccaaa tctagcttct cttcgcgctt atgagcaatg atttctttat
     6541 tcttatcata taacctaact tgtacattac taccgctaga accccaatat ttcgtctcta
     6601 attcgccccc tctaccatag aagaccttat gggtaacacc acctttaata tgttgcaaat
     6661 taacgatttc aggcctgttg aaaatgtcaa atgtcaaatc aaaacgagac aaacgtaccg
     6721 tcaatgaatt caatctggca aagtacatta attgcctcca tactttcatt ccatcaaatt
     6781 cttttaaagt gttaggattg aaatcaatcc gaatcaattg ttcacctcca taagtggata
     6841 attggaaaaa tataatattg attgaatcat actcattaaa atccttagct aaagtaaaga
     6901 catcatctcg cacgttatca tgtatttcaa atgagtcaac tcttgtactt attgcctgtt
     6961 tcagattttt gaaaattcgt cttagggaac cagtgtctgt atcccagata accgttaatc
     7021 tatcaatact gacatctaac ctctgtacta attctcctat ttcacatcgt tcttgaatgc
     7081 ttcttaaatc ttgtatagaa accaacaaaa ttgtcccccc ttcttttaga ttttttaggc
     7141 ctcagaaaca ccgtcaaatc aacgtttgct cgttccgtcg ttctttggac gttgtcctaa
     7201 gtgtaccttt ttgctggctg ttagaatagc cagcttttgc ttggctagaa attgtctgga
     7261 cggcagcctg caggacttcg cctgacttca cgtcaggctc gtcccttgcc cttgtccaca
     7321 caatttctag ctccaaggct tcgaatagtc atcagtcata gtcatagtct cgtcctcaaa
     7381 ttcctcctca ctcactattc ctaaacatat gagctatttg tatcatttat aacttattta
     7441 taagttataa atatatttta taaaaaaata ttttaatcag tcaactaaaa acttgatttg
     7501 taagtttata ggtgatagaa taagtttaaa atacaacata ggagtttatc atgaccttta
     7561 ttattcagaa ttttggaccc aatttggcac gactacgcat agaaaaagga gtaagtcaaa
     7621 ctcaacttgc ggaagattta ggaatcggta aacaatccat ctctgactac gaaaaacaaa
     7681 aaagctatcc tacctttgca aatttggata agatagcaga atattttaat gcaactccaa
     7741 cccaactatt tggaactagt aaagagattg aattagaaaa gagtgttctt gaatcgaatg
     7801 aatactctga taaagtaagt gagatcttaa aggctgtcaa atacatcgaa aattttctag
     7861 aaactgatgg acagtactta gaggatttac tttacctaac aagaggcaaa caactataca
     7921 cagaagatgg agacgagttg tatactgatc caacttctca gaaaagaaca tttcataacc
     7981 aatatgaacc tggttttatt gtagcaagag acaaatctcc actagaactc ttgattgaaa
     8041 ataaggaatt atttgataaa tagaaaaagc gagtttgaac tcgctttttc tgttatgaaa
     8101 gaaataactt attttctagt tttttagata aatcctctct ccaaatatcc gtcacggtcg
     8161 cttcttccca gttctttggg cttacgcaag attttaatca attttgagtt aaaaataaat
     8221 actctaaata ctcattcaat tcattaatta tttagtcaat ggttgctttg tatccacaat
     8281 tccaaatagt tctaaatgag attttaggaa ctttgaaaac tttaaaaaac gcattcttat
     8341 cactttgaag ataagaaaag agagaacgaa ttgtgtcctc tctcgatgtt agcttttcat
     8401 caactcaaga cagttgacaa agagcctttc agatatacaa tttgtctata gacactattg
     8461 gcataactac tttttcaaat gaatcacttt atcatagcgc ttcaagtctt ccttggtgta
     8521 gtggtgaatg acctccacca cagcttgagg aagtgaaaag agcagctggt tgattttttc
     8581 ttgatttttg gcgtccaggt tagccttgac ctcatctgct aggataaact gtcgcttgtg
     8641 atagagagca cgggcgattt caaggcgctg tttttcaccg cctgataaag tttggttgct
     8701 gggtaccttg ccttttaggc tgaggagccc tgtttcttgc aagatgttat ccattctttg
     8761 ctggtcaatt tcctgtccca gagcgatgtt ttcctccaca gataaatcgt caaaaacatg
     8821 actagattgc aagatatagg caccagcctg atagagttga cagctggtta gttcccgtcc
     8881 ttgataacga atttgcccct gactaggatg gatttccccg tataggatgt tgagcagggt
     8941 ggttttgccc gctccgcttt ctccgatgat agcaatcttt tccccagcgt ggatagtcag
     9001 atcacaagga gctagaatgg tctccccatc cttctccaca ctgacctgct ccaactggat
     9061 aggaaagaca gattggtcaa atatgctgtc agtagccaac ttatttccaa acaagtcttg
     9121 atacttatcg cagagggact tggcagactt gcgggtattg ataaagtagg acagttcttg
     9181 aaactggtag ccgatgttgt gggagaccag ataaatgccg acaaaactag ccgcagaaag
     9241 gtagttctgg taggtcatga atccgccaat cacaatgggc gccacagagc aaaatgcatc
     9301 tatactgttg ataaataaac tgttcagtga ccgttgcttt tcgtaggaca cttcttcttg
     9361 caacgcctgt tctaggtctt tagaaaatct cttgaaaaac aaattctggc cctgataatg
     9421 acgaatagga gcaacacctg caatcatatt gttgacacgg gcgatataat tctgatttgc
     9481 cagggatttt tgctccgcaa tcccatccaa acgcttcgaa cccagtccgc tacacaaaac
     9541 tggtaccgag taaaagatga taaacaataa ccccagatag aaattggtcc agagggcata
     9601 tgcgatggaa acgactgtaa aacctagcga ggatacgata atgacggtcg gctctatata
     9661 gctattttcc aactgttgga catcattttc cagatcagac agcacctcct catcaggaat
     9721 ctgacggctg tataaaaaag tccgaaaaat agcgcgtttt atcccaacct taaagtcagt
     9781 catcaaacga gcatagtaat agcgcttccc agccaagccc aggacaagca ccagattgcc
     9841 cccaatcccc cagagcaaaa tctgccagag gagatgcaac tggcggttgg taaaactagc
     9901 gacgatatac tggataaggg caggggtgat aatggcctct aaccaagtga tgacgatggc
     9961 tagaaaatag aaggtgagat gttttttcgt tacataactc ctaagcatag cgtataaacc
    10021 ccctaaaatt atttaccaac ctagataatt tttctctgtc cttggataaa tatataatct
    10081 gtttaataca gtattccatc agttctggtt tagagcattc aagaaattcc ccatcttcac
    10141 taattacaga agaatatcca tcaataacat tggcaacgca ttccaagcac atacctctac
    10201 accagcagtt tttacacttt tcaaagttat ctttgttgtt aaatgattcc gctttaggac
    10261 tgttgtgagt tccccaaaat ctgaaacata gtttcttact accatctaca tcataagtta
    10321 atgtattcga agggtcaata tcatcacaaa atgtacgatt cgtactcttg tatatcattg
    10381 atattaatac atcatataaa ataggactga taaatgcctt ctcattgttg ttgattacat
    10441 gttgaatgga tttatctatg aactgttttc tttcagccaa acttttttcc atttctttca
    10501 caattagcac tttattttta gtaaaaacat catttatatt aaaatgcaca tccatatcag
    10561 taaaatattg aaagatatct tctctactta gaccattttt ttgatgaagt ctagtatatg
    10621 tcgaggctat ttcaaaattt tcataatcaa tattctttaa ataattaata aaacgtaatg
    10681 tttttcgatg gctccctctt cctctgagtc tatcatgaac aatttctggt ccatctaaac
    10741 ttatggttaa ataaggatga aatttaacaa gcatttcttt aacacgctta tttaaaacag
    10801 taccattagt aactgtttca attttcacta catttaataa tgtagataat ttttctataa
    10861 aatatataaa taattctata tttaaaaaag gttctccccc gaaaagtatg agacggttga
    10921 tttgtgtaac tcctttactt gctatctctt ggataatatt atcagcagta gttaaatcca
    10981 taatacgatt atccatacca tagttaccac catctgcata acaatacgaa caagataaat
    11041 tacaactatt agaaatattt ataactactt tttttaatac accatcttca acagaatcta
    11101 gagttggtga actttgtttt gaaataggtg acaaagataa agtaaaatta acagaatcaa
    11161 aataatatgt tcctatatct gtttctattg tctttatcat aattatcctc cagactaaaa
    11221 actgagatga ggaatcactc ctcatctcgg aagaagctat cgaccaccgc cacaagaatg
    11281 acttggacca cagctagcat taattacata cccttgatca aactctaaaa gttcttcaag
    11341 gtcaatcacc tgaagttttt ccatggtttt tacctccttt atttgatagt ttcattatat
    11401 aaccttatca gaagaggata atattttccc ttatacgcaa ttcacctcat gtcatctaat
    11461 actttttgta aataattttc aaattttata gctatttgat tgctatctac caatttcgtg
    11521 gcagcaatac attttctcat ttccaaaaca gcatgtcgat tattattttt ctttagatca
    11581 tataaattat tagcataatg gagcactagt ttttcataca tttcagtctc tgaaaagtta
    11641 caatatttta gctgtttttc aaaataaaga gcgtccatcc attcattgcg ttcaatacag
    11701 gtgatataag cattgagcaa catagttgcc aataaacgtc tattatttgg aatatctcta
    11761 taaaaatccg aacgatgaca catttctttg gctaaaatca tcattgtgtt acgattaaaa
    11821 gcgtctattg tattcataaa cagtagcaat tcataataac cccagtattc cgcagaaaac
    11881 aagtaatcac tgatagtaac aatctcttgg tctgttacat aagtttctcc tgataaatcc
    11941 tgtaatctta ttttaatcaa aattgtgtta aatgaagcga aaggttcctt tttatccttc
    12001 ttttccattt ggctaattaa tagctttttc attccgtcta tatcacgatt tgatactaaa
    12061 taccgaatct tttctaaaag ttcattaaag tcatctctgc ggaaatcacg tacagcgtaa
    12121 acaaattctt cgataggcat atgtattgca tctaacgcta aaaaaaattt gctgatggtt
    12181 aaatcagcct catcattttc aaatcttgag agatgggaac ttgaaagacc tgattttgca
    12241 acatttttta aagataaacc tcgagattct ctaaattttt taaaaatttt tccatatttc
    12301 attctagtca cctcctaaat tgcttataag ggaaatttct tcacaaatat taaaaatatt
    12361 atatcatata agaaaacgaa aagaggtatt taccatgaat aaaaaagcat tgtttagttt
    12421 gttgtttgta atacttgaag gtattatcgt tatcggagta ggttagccaa atgataaaga
    12481 gattaggcaa gaaaccttaa aaataaaaaa tagcttagaa ttgcgtcatt ataaacgttg
    12541 attccaagct atttttggtt attaaaattt taatcagaag ggtaaacttg tagtttttgc
    12601 ccaacctctc ttgattttat ggaaaaagaa tcccgtattt tggatacgaa atgctttcaa
    12661 taagtgtaaa tcagttttaa cgtttactaa atttcgatgc tttacgagcc tttttcaagc
    12721 ctggttttca aagcaagttg gaaaccttta tgagtcattc gtttttgccc cacttttgcc
    12781 ccattttgaa ataattatat ttaaaaatgc tccaagtatc ttctaaaaat aacttatatt
    12841 tcaacatttt tgattatttt caatatgaaa aattcataca aattcatgta gggggcatct
    12901 aatttcaaca gtaaaagcct tggtttacaa ggcttttttg cttgtttaaa tgaagtttgt
    12961 cccaccattt gtcccacatt tttggctctt tgtcaactgt agtgggtgac ggaaagactg
    13021 ttcagggagc aattatcgag acaaaaaaga taagatatta ggattcaaaa ataaaatcaa
    13081 aaaagctatc actggttgtt gtgatagctt ttttagattc ctataaatcc tagtggttcg
    13141 atttatagtt tctatttttt atattgactc aaatcctgtt tcatgaggaa aaagaaaata
    13201 tcaccgtagg ttccatgata gtctaaatcg tagccattat aggttaattt ttggacagga
    13261 taatagtctg ccacaccaat tagacaagca tgttgagatt gctcaaattc atcataactg
    13321 ttaaaacgaa caactctttc ttgttttgca gaatcaagat aagtaatttc aatcatattt
    13381 ttgcccctct ttctttattc caagatttta ataccagaga ttatatctgt caaagaaaat
    13441 aactgatata tctaaagata aaacaaatta ccctttacca tcttgaaaag cgggataaag
    13501 tgtcatgcca ccatcaacaa atagtgtaat accagtgaca tagcttgatt catccgaagc
    13561 taaccatgca gcagctgcag cgacttcttc aggtttcccg atacgatgca ttggaaccat
    13621 cctagcagtt tcttcgtatt ggagtggatc taagaattta tcggaattga taggggtgtt
    13681 aatagctccg ggaccgatat tattaacacg tatgttacgt tttccgtact ccatagctat
    13741 cgtttcagtg aaaagcttta ctccaccctt tgaagcagca taattcgcaa atcctggcca
    13801 tggaatctgt tcatgaacag acgacatgtt aataatattt ccttttctct cattatcagt
    13861 aaaatattga agagcaacct tagatcctaa aaacacacca gtcaagttag tttttataat
    13921 acgattccaa tcatctaaac tcaattcatg agtggcgctg cgattctcca cgcctgcatt
    13981 attaacccag acatcgatac tgccaaaaaa ctcaagagct tggtccaata attttttgac
    14041 tccagattcc tcaccaatat tggcttgaac agctacccct ttaccaccag cttcttcaat
    14101 aatgcgaaca gcttcttcag ctcctttact gtcagaaaaa tagttgacaa caacattcat
    14161 gtgttcggta ccaaaacgtt tagcgatagc agtaccaatg ccttttgagc caccagtaac
    14221 aacggcagtt tttccctcta attctttgta cattaaagac ctctttctct ttggtactgt
    14281 tattataact ccttattcct aaaagcgtat tgaaaatgct tgggaaaatt ttaacacgtt
    14341 tgattgacaa gttgtagcgt tgctttactt agttcaactt gtaataaaga gaaaaaataa
    14401 aaagtgtcat tatttaaagg aaatattgaa gcgttttcaa aagtgtttta taataacttg
    14461 aaattaaatt aagtgagaga gttttatgaa attttattcc cattcatcac agagtatggt
    14521 aaagggggct taatgtggtg acttactaaa gatactcttc aaagtcggga gtgtctaatg
    14581 ttagggaaat tatgttatta agttttgtcc ccgatttgtc cctttttcaa ttttaaatag
    14641 tggctactgt taaaaacatg tgcttcaaac cattggtaat tcaatgattt ttgactaata
    14701 taagttgaaa tttactttta aaatgcatgt agggggcatc taaatacaac aggaaaagcc
    14761 ttgatttaca aggctttttt tgcttgttta aacatgaatt attgcctcgt aagatatctg
    14821 ctttatgtta tgatatcagt caagcaatag aattgaagaa ggaggcatgt gttgaaaatt
    14881 gcaatcattg gctatagtgg ttctggaaag tcgactttgg caagtttttt aggtcaacac
    14941 tacagttctg aagtacttca tttagataaa attcatttca catcaaactg gcaagagcgg
    15001 acagttaatg aaatgactga taatatatca aaatttatgt cacaaaaggg ttggattatc
    15061 gaaggtaatt actcgacttg tctttatgaa aaacgtatga gagaagcaga ctgtattata
    15121 tatttcaact ttaacagatt taattgtctc tatcgggctt ttaggcgata tttaagatac
    15181 aaggggtaga cgtgtcctag catggcggaa aattgtaata aaaattcgat ttcgaatttg
    15241 tgaaatggat tctattagat ggacgttcac aaaagaatgt aacgaaattt aaagttgttg
    15301 taaaaaa
//
