GCA_027857875.1 - 6 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaIKNLLDKJ_10 (original name was: gnl|Prokka|IKNLLDKJ_10)

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	lanthipeptide-class-iv,RaS-RiPP	1	18,357

gnlProkkaIKNLLDKJ_12 (original name was: gnl|Prokka|IKNLLDKJ_12)

Region	Type	From	To	Most similar known cluster		Similarity
Region 12.1	NRPS-like	1	28,742

gnlProkkaIKNLLDKJ_16 (original name was: gnl|Prokka|IKNLLDKJ_16)

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	RaS-RiPP	1	13,862	streptide	RiPP	75%

gnlProkkaIKNLLDKJ_34 (original name was: gnl|Prokka|IKNLLDKJ_34)

Region	Type	From	To	Most similar known cluster		Similarity
Region 34.1	NRPS-like	114,735	141,823	asukamycin	Polyketide:Type II polyketide	4%

gnlProkkaIKNLLDKJ_56 (original name was: gnl|Prokka|IKNLLDKJ_56)

Region	Type	From	To	Most similar known cluster		Similarity
Region 38.1	RaS-RiPP	97,221	119,326

gnlProkkaIKNLLDKJ_67 (original name was: gnl|Prokka|IKNLLDKJ_67)

Region	Type	From	To	Most similar known cluster		Similarity
Region 39.1	RiPP-like	70,669	83,588

Region	Type	From	To	Most similar known cluster	Similarity
Region 10.1	lanthipeptide-class-iv,RaS-RiPP	1	18,357
Region 12.1	NRPS-like	1	28,742
Region 16.1	RaS-RiPP	1	13,862	streptide	RiPP	75%
Region 34.1	NRPS-like	114,735	141,823	asukamycin	Polyketide:Type II polyketide	4%
Region 38.1	RaS-RiPP	97,221	119,326
Region 39.1	RiPP-like	70,669	83,588

Compact view

gnlProkkaIKNLLDKJ_10 - Region 1 - RaS-RiPP,lanthipeptide-class-iv

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Location: 1 - 18,357 nt. (total: 18,357 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-iv: (cds(LANC_like and Pkinase) and not micKC)
RaS-RiPP: (PF04055 and TIGR01716)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Lanthipeptides

Core peptide predictions

No core peptides found.

gnlProkkaIKNLLDKJ_12 - Region 1 - NRPS-like

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Location: 1 - 28,742 nt. (total: 28,742 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 28742:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ala)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg12_8

Search NORINE for peptide: strict or relaxed

AMP-binding (9..397): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVTAVAAVYK
Nearest Stachelhaus code(s):: Ala DVFSVAAVYK (68% 8Å match)
Stachelhaus code match:: 80% (moderate)

gnlProkkaIKNLLDKJ_16 - Region 1 - RaS-RiPP

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Location: 1 - 13,862 nt. (total: 13,862 nt) Show pHMM detection rules used

Region on contig edge.

RaS-RiPP: (PF04055 and TIGR01716)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaIKNLLDKJ_34 - Region 1 - NRPS-like

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Location: 114,735 - 141,823 nt. (total: 27,089 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

NRPS/PKS substrates

NRPS/PKS substrate predictions

ctg34_159

Search NORINE for peptide: strict or relaxed

AMP-binding (6..388): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVTSCALIYK
Nearest Stachelhaus code(s):: Ala DVTNFALIYK (62% 8Å match)
Stachelhaus code match:: 80% (moderate)

gnlProkkaIKNLLDKJ_56 - Region 1 - RaS-RiPP

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Location: 97,221 - 119,326 nt. (total: 22,106 nt) Show pHMM detection rules used

RaS-RiPP: (PF04055 and TIGR01716)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaIKNLLDKJ_67 - Region 1 - RiPP-like

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Location: 70,669 - 83,588 nt. (total: 12,920 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.