LOCUS       gnlProkkaKIOLHBIL_15   12400 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KIOLHBIL_15.
ACCESSION   gnlProkkaKIOLHBIL_15
VERSION     gnlProkkaKIOLHBIL_15
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 16:17:07
            Original ID  :: gnl|Prokka|KIOLHBIL_15
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12400
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12400
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[3734:6731]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3735..6731
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..12400
                     /SMILES="NC(C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12400
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             213..1553
                     /locus_tag="ctg15_1"
                     /transl_table=11
                     /translation="MDKFPGFLSKQIVRKLVELKLDDITIVKKVNLKDNITKTNEKVDI
                     PPSKHAYSRLVPLELINDNIKIENIPNTIDSYYLNNLLNRVNKHCSNECFFIDDDEISN
                     CWSMVNILPAVVWKVGKVYLPGKPSGCSIGKRPMNLYLKIMKDFGFEITENNGGFYLEK
                     GNAGISEITLPFPSFTGTSIAIYLAMLSNNEININNVSIEPEIIYLISVIKNLGYKIIF
                     DKIARVIKFKGKTENNGVLSVRVPFDRNVLVTRMVSDLVSYGKFEWLNEEQHYLEELLL
                     FLKKCGFEIYSDDYRIKIVALDKVVDQERVVLNCGHFPKICSDWQPLLVILLCHYLIPF
                     ELSDDVFENRFQIFSQLVYLNNNIVLNKKSSNKIVIDYCDTTEKITTSSNLEFKLLNIR
                     DAAAILIASHQSKLNIEFSNLLQLFRGYETLENVLGEKVELYSYEKQ"
     CDS             1540..2625
                     /locus_tag="ctg15_2"
                     /transl_table=11
                     /translation="MKNNDIIEFIRTKISREFNLEDELDGISIHIVGSLAIKIRLGGSL
                     ENYFNGESDIDCIVVVLENGIITQNSKIFERKVLDTFLNNQVDVINYSIVYGKKRNSIN
                     IKFIKKENLYKLTDIREVNFKSMRKDSLVRHKPVTKFYGEESEIEFEFEYLEKQAGELY
                     MIEYHFFTFSNNIFFLCDIHSMLLFSLNISNKNYKDLPEIFFLKMELYSILKKKDDLYY
                     FSMFKNFHHIVKSPKELSKLVPKLSIFLIDKDESIDLLTYFEIRKLNRDASLDPIIINC
                     GVREPHDFIKTDFLNFKIYTALEILENFSWIKTIQDSKIYLEANENDNLYSVIELFSLF
                     EEFSNKLNNIFASKKFVAIKI"
     CDS             2622..3149
                     /locus_tag="ctg15_3"
                     /transl_table=11
                     /translation="MSRFEDYYDKKLFFQMDSKVSSNLNFLGGLEDCFYKLVKLNDTEL
                     IKMSDEFFSEKTKKIENIIQKYNIIVKLVSFLCNEDASNTSKSLKNFFEELTNTKAKML
                     KNIKKIPPSSDTASLIDVLFLSGDFKSKNELHRLFKQNSVKSLSGEILKQGCIDFKGEV
                     IKIGKRRYYKIE"
     CDS             3142..3690
                     /locus_tag="ctg15_4"
                     /transl_table=11
                     /translation="MSKNFSKENNVGVLIWARSTPKENIFQEMISLVEQNYKKNIIFFV
                     DDLCPQQVYNRSKETQNFYNEKYRSYFKSKNVQFYFSSQLVSLEKIDNHYLQEMIDDMT
                     IKEYVTILPHKKHENGEFELNEVIHTIFQELLLKEALSMVSTILLGKFSQNLVIFHKKI
                     TGQNIETIIIERMSYNRRK"
     CDS             3735..6731
                     /NRPS_PKS="Domain: AMP-binding (9-397). E-value: 1.8e-65.
                     Score: 213.0. Matches aSDomain:
                     nrpspksdomains_ctg15_5_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (498-564). E-value: 6.7e-17.
                     Score: 53.7. Matches aSDomain:
                     nrpspksdomains_ctg15_5_PP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     185.1; E-value: 3e-56)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_5"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-70, bitscore:
                     227.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-17, bitscore:
                     53.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPISNVILKLEESASHYPKKTAIYGINKNFTYEEVQRITSFFSNY
                     LGKIVGKNKNIGLILEHNENIIISFFSILKSNNTYVPFSTKTNFNRIKDSIDDLNINYL
                     ITDNYNFSTIQEEFKGNYIINIDDYLDISQIPSNYKKEIEDSETQDIVYIMHTSGSTGK
                     PKGVKVTVNNLNYITENVQRITPCDEDSTLLFMTPYTFDVSITEICGWVYNGGAVVCRD
                     LNSNTWFDDIREVLYKYNITHVAACPSVFLTMMNIYSNEINIFNNLKFVVLAGERFSLN
                     IHKVWKESNWSFRLFNAYGPTETTVYCTLYELSKESSYDEIPIGTPLQGVEYIIDENTS
                     ELLVSGQCITNGYLDYENTSKYFINVNDCLYYKTGDLVELNGGLLYFKGRNDKQIQLNG
                     MRVELGEIENRIEEIEYVDQSKVIYKNNKIIAFIKTKYFDEEYFKNYFSQNFEKHLIPN
                     NFHLVSEFPLNQSKKVDKDRLMYNFLDTEESDSMLNELELEIKDLFENVITIGKEKITK
                     NSNFFNLGGDSLSSVLLLMGLEERFNISITLSDIYNYPTIMQLSKYIDSLKKNKNIDDE
                     PKKNENIKIDINTMTAELKNVENYIYRSGQIVSKYETLHLQRVYYYDNFESFIEFEYVF
                     QKGEAFEVVVGLINDLIANVTMLRTSFVFEDDKLYFVEKAMENLDSMPIFDVSYQSIDY
                     ISDIKKNIRMILMDSRKEGGLLNSLILLKNDKQYTLIGLMDHSIADASTPATILEIISN
                     LKNGKKINFESTYEDYIKLIHKNNNMYEIMKSSFYQDLVKCGEDSEFEIKKMESSLNVY
                     KVDLESDAKSLSTQQINLFLAYNIGQYLLKLFNQHSIVIKCLANGKDYLGTKYKYTLGD
                     FHTSIYIVVYKDENYLDYKKRVEDSIKTNYVEKVFRPAYVYGSNYPIKNNDQKLLKNSL
                     RHTTNTSIDFLGIIKEDDLERYTKSVKQSLYQLTQIDDTLYVTVYLVNNQLVIYTNKDF
                     LDFETFVKL"
     aSDomain        3762..4925
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg15_5_AMP-binding.1"
                     /evalue="1.80E-65"
                     /label="ctg15_5_AMP-binding.1"
                     /locus_tag="ctg15_5"
                     /protein_end="397"
                     /protein_start="9"
                     /score="213.0"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="LEESASHYPKKTAIYGINKNFTYEEVQRITSFFSNYLGKIVGKNK
                     NIGLILEHNENIIISFFSILKSNNTYVPFSTKTNFNRIKDSIDDLNINYLITDNYNFST
                     IQEEFKGNYIINIDDYLDISQIPSNYKKEIEDSETQDIVYIMHTSGSTGKPKGVKVTVN
                     NLNYITENVQRITPCDEDSTLLFMTPYTFDVSITEICGWVYNGGAVVCRDLNSNTWFDD
                     IREVLYKYNITHVAACPSVFLTMMNIYSNEINIFNNLKFVVLAGERFSLNIHKVWKESN
                     WSFRLFNAYGPTETTVYCTLYELSKESSYDEIPIGTPLQGVEYIIDENTSELLVSGQCI
                     TNGYLDYENTSKYFINVNDCLYYKTGDLVELNGGLLYFKGRNDKQIQL"
     aSModule        3762..5426
                     /complete
                     /domains="nrpspksdomains_ctg15_5_AMP-binding.1"
                     /domains="nrpspksdomains_ctg15_5_PP-binding.1"
                     /locus_tags="ctg15_5"
                     /monomer_pairings="Ala -> Ala"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4191..4244
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg15_5_0001"
                     /evalue="6.00E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg15_5"
                     /protein_end="170"
                     /protein_start="152"
                     /score="21.9"
                     /tool="antismash"
                     /translation="YIMHTSGSTGKPKGVKVT"
     CDS_motif       4893..4958
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg15_5_0002"
                     /evalue="3.90E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg15_5"
                     /protein_end="408"
                     /protein_start="386"
                     /score="25.6"
                     /tool="antismash"
                     /translation="FKGRNDKQIQLNGMRVELGEIE"
     aSDomain        5229..5426
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg15_5_PP-binding.1"
                     /evalue="6.70E-17"
                     /label="ctg15_5_PP-binding.1"
                     /locus_tag="ctg15_5"
                     /protein_end="564"
                     /protein_start="498"
                     /score="53.7"
                     /tool="antismash"
                     /translation="EIKDLFENVITIGKEKITKNSNFFNLGGDSLSSVLLLMGLEERFN
                     ISITLSDIYNYPTIMQLSKYI"
     CDS             6915..8144
                     /locus_tag="ctg15_6"
                     /transl_table=11
                     /translation="MKILLNKYTPTLAKLNYLADQDAIVIAPLDTQKKYEKYLMKGNRL
                     PKIIYLEDYTLPKMISIIRESIDVDSIEEVLTLDEHYMWHAGFLNDYFKKKNSSYLVNS
                     LFQDKYLMRSVLFEIVPQPMFRLIETQKDIELFWKNTAGDKSIIKPRFGAACVGIKKYS
                     RGEQIPEKFINSQYIIEEYVDLQKMLTCDGYSQGSNIIRFYSHEYEELLLGTIGTSDEF
                     TVRTNSLYEKNIPFLRKIFSECSKVLKEFVNDYSIIPFHFEWFFDENKGEFVFCEVGKR
                     FGGGDIPNLIQRSFGVNIFEEFWGNVFDNKELHPSTDLERPKFISATYCPYKKRGKLVS
                     APDMELFEWTDEIYVFSKVGEESDGITSVVEGDFIAIIVSETEEQHNQKLSKLRELSEQ
                     FIWEERFERR"
     CDS             8131..9342
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 263; E-value: 7.3e-80)"
                     /gene_kind="transport"
                     /locus_tag="ctg15_7"
                     /transl_table=11
                     /translation="MKDVKKKNILYLVSSKGVSRIGDTMFDFANNTFLAGINPTSLSLV
                     AVYQSLESVIGVLFNLFGGVFADSFKRKKIIIATNILCGIACLVLSFISQDQWLVYAIV
                     LTNVILAFMSTFSGPSYKAFTKEIVKKDSISQLNSLLETTSTVIKVTIPMVAIFLYKLL
                     GIHGVLLLDGLSFLIAALLIFFIVPINEAVVTKEKMTFRGIINDLKIGFKYVYNHKSIF
                     IIIVLSALVNFFLAAYNLLLPYSNQMFGEISTGLYGTFLTAEAIGGFIGAILSSFVNKK
                     LSSKKLMLFLSLSGLVLMLATPFYIMFHNVIILAISPALFSLFLSIFNIQFFSIVQRDV
                     DNEFLGRVFGIIFTVAILFMPIGTGFFSVVLNPNNTFNLFIIGASITVLSLVFGILFKR
                     YNMS"
     CDS             9512..9664
                     /locus_tag="ctg15_8"
                     /transl_table=11
                     /translation="MGSLSTVLGDEKLTSREDPIGPLRLKTKSSEVILLGTFLASKEYN
                     KRKGI"
     CDS             9677..9895
                     /locus_tag="ctg15_9"
                     /transl_table=11
                     /translation="MFHKDNPEYNHRQIGFYTLDELVSKDHFLRKVEETIDFSFIYDVV
                     EDSYSSDNGRPSLDPVLLVKIPLIQCF"
     CDS             9908..11026
                     /locus_tag="ctg15_10"
                     /transl_table=11
                     /translation="MRQTIKDIEVNTAYRWFLGLSLDDKVPHFTTYGKNYSRRFQNKEL
                     LAHIFSHVLHHVLEAGLIDPSEIFIDGTHIKTAANNHKYKNVVVDQKAKFMSEQLEIEI
                     NIDRRKHAKKFLKPAKKGEAKPKKQSMTDPDSGWFHKGEHKEVFAYNAQVACDKHGCAL
                     AYTVEAGNIHDSQVFPAFFAKLESFSPEFIIADSGYKTPSIAKFLLEKGITPVFPYTRP
                     RGKKDFLRPKDFVYDEHFDCYLCPENKILTYRIMTREGYREYKSYPKICKTCPLLAICT
                     ESRQHQKVVVRHIWKDALEVCEDIRYQSGMKELYQHCKEMIERLFRTAKKYHNLRYTRE
                     EGEFCYFKCIKIVEGLSQNIKRQTSKECLSLL"
     CDS             complement(11140..11751)
                     /locus_tag="ctg15_11"
                     /transl_table=11
                     /translation="MVKNQYEGYKYIDPNNQYTYPDSTVLVNKQNITNIEEAYRNEHLF
                     VTRRLADLRLEPIQVYSMSDILAIHNYLFQDVYAWAGQYRKVNISKSGNPFMPIQSFNT
                     AETHMNHLIHSYHQTANSKDEIIMHLTEILDNLNYFHPFREGNGRTQREVIRALALSKG
                     YSAQIRVEQDDEVYNLYMDGTVHEDLEKLKELFIRILSKL"
     CDS             complement(11744..11932)
                     /locus_tag="ctg15_12"
                     /transl_table=11
                     /translation="MTLDVNEEELTILGISFDNYSDFDTVWYAIGSSMIENYEPTVQDV
                     IDLKTYVTNRRKELNIG"
ORIGIN
        1 gttttgacaa gattttttca tcatcagtaa ataaatgcat cgtgtttaac ctcgtttatc
       61 gagttttata cttgtatttc tattatctca ttttataggt tttttgagaa gtttttagag
      121 gtgcccttat atattttata gcttttacta ttaatagtaa tattaatcta tgtaacggct
      181 taaactcata taaatgggtt gatattgaag atttggataa atttcctggc tttttatcta
      241 aacaaatagt cagaaaattg gtagaactaa aattggatga tattactatt gttaagaaag
      301 taaatttgaa agataatatt actaaaacta atgaaaaagt ggatatacca ccgtcaaaac
      361 atgcttactc taggttagtc cctttagaat tgattaatga taatatcaaa atagaaaaca
      421 ttcctaatac aatagattca tattatttga ataatttact aaatagagtg aacaagcatt
      481 gttcaaatga gtgttttttt attgatgatg atgagatttc gaattgctgg tcaatggtta
      541 atatcttacc agctgtagtt tggaaggtag gaaaagttta tttacccgga aaacctagtg
      601 gttgcagtat tgggaaacgg ccaatgaatc tttatttgaa aattatgaaa gattttgggt
      661 ttgaaattac tgaaaataat ggaggatttt atttggaaaa aggtaatgca ggaataagtg
      721 aaattacttt accatttcct tcatttacag gaacatctat agcaatttac ttggcaatgt
      781 tatcaaataa tgaaataaat attaacaatg tttcaattga accagagata atatatttaa
      841 tttctgttat aaaaaatctt ggctacaaaa ttatatttga taaaattgca agagttatca
      901 aatttaaagg aaagactgaa aataatggag ttttatctgt cagagtgcca tttgatagaa
      961 atgttttagt tactagaatg gtatcagatc tagtaagtta tggaaaattt gaatggctta
     1021 acgaggagca acactatttg gaggaattgt tactattttt gaaaaaatgt ggctttgaaa
     1081 tttattcaga tgattatcgg ataaaaattg tagcactaga taaagtagta gaccaagagc
     1141 gtgtggtttt aaattgtggc catttcccta aaatttgctc agattggcaa ccattacttg
     1201 ttattttatt atgtcattat ttgattccgt ttgaactttc agatgatgtt tttgaaaata
     1261 gatttcaaat tttttcacaa ctagtgtatt taaataataa tattgtttta aataagaaat
     1321 cttcaaataa gattgtaatt gattattgcg ataccacaga aaaaattaca accagctcta
     1381 atttagagtt taaattatta aatatcagag atgctgccgc aattttaatc gcaagtcatc
     1441 aaagtaaatt aaatatagaa tttagtaatt tgttgcagct ttttagaggt tatgagactc
     1501 ttgagaatgt attaggtgaa aaagtagaat tatatagcta tgaaaaacaa tgatattata
     1561 gaatttataa gaacaaaaat ttctagagaa ttcaatttgg aagatgaact agatggtata
     1621 agtattcaca ttgtcggatc attagcaatt aaaataagat taggggggag tctagaaaat
     1681 tactttaatg gtgaaagtga tatagactgt attgtggtag ttcttgaaaa tggaataata
     1741 acacaaaata gcaaaatttt tgaaagaaaa gtgctagaca ctttcttaaa taatcaagta
     1801 gatgtgatta actattctat tgtatatggt aaaaaaagaa acagtatcaa tatcaaattt
     1861 atcaaaaaag aaaatttata caagcttact gacattagag aagtaaactt taaaagtatg
     1921 agaaaagatt ctttagtaag acataaacca gttaccaaat tttatggaga agaaagtgag
     1981 attgagtttg agtttgagta tttagaaaag caggctggag aattatatat gattgaatat
     2041 cattttttta cattttcaaa taatattttc ttcttatgtg atatacactc aatgttatta
     2101 tttagcttaa atataagtaa taaaaattat aaagatcttc cggaaatatt cttccttaag
     2161 atggaattat attccatctt aaagaaaaaa gatgatctat attatttttc gatgtttaaa
     2221 aattttcatc atatagtaaa atctcctaaa gagctttcaa agttggttcc gaagttaagt
     2281 atttttttaa ttgataaaga tgaatcaata gatttactca catatttcga aattagaaaa
     2341 ttaaatagag atgcatctct agaccccatc attattaatt gcggagtaag agagccacac
     2401 gattttataa aaactgattt tttaaatttt aagatttata ctgctctcga aattttagag
     2461 aatttttcat ggataaaaac catacaagat tcaaaaatct atttagaagc taatgaaaat
     2521 gataatctgt actctgtaat tgaattattt agtttatttg aagaattttc gaataaacta
     2581 aataatattt ttgcatcaaa aaaatttgta gcgataaaaa tatgagtaga ttcgaagatt
     2641 attatgataa gaaattattt tttcaaatgg atagcaaagt atcttctaat ttaaactttt
     2701 taggcggttt ggaagattgc ttctacaaat tggtcaaact taacgataca gaattaatta
     2761 aaatgagtga tgagtttttt tctgaaaaaa ctaaaaaaat tgagaatatt attcaaaaat
     2821 ataatattat tgtgaagtta gtatcatttt tatgtaatga agatgcttcc aatacctcaa
     2881 aaagtttaaa gaattttttt gaagaattaa cgaatacaaa agcaaaaatg ttaaaaaaca
     2941 taaaaaaaat acccccctct agtgatactg ctagcttaat tgatgtactg tttttatctg
     3001 gtgattttaa gtcaaaaaat gaacttcatc ggctttttaa gcaaaactca gtaaagtcat
     3061 tatctggtga aatactaaaa caaggttgta tagattttaa aggagaagta attaaaatag
     3121 gtaaaaggag atactataaa attgagtaaa aactttagta aggaaaacaa tgtaggtgtt
     3181 ttaatatggg ctagaagtac tcccaaggag aatatttttc aagaaatgat aagtcttgtt
     3241 gagcaaaatt ataagaaaaa tattatattc tttgttgacg atttatgtcc tcagcaagtc
     3301 tacaatagaa gtaaggaaac tcaaaatttt tataatgaaa aatatagaag ttatttcaag
     3361 tcaaagaatg tgcaatttta ttttagtagt cagttagtta gtttagaaaa aattgataat
     3421 cactatttac aagaaatgat tgatgatatg acaataaaag aatatgtcac aattcttccg
     3481 cataaaaagc atgaaaatgg tgaatttgag ctaaatgaag ttatccatac aatttttcaa
     3541 gaattattac ttaaggaagc actttctatg gtctcaacga ttttgttagg aaagtttagt
     3601 cagaatctag tgattttcca taaaaaaatc acggggcaaa atattgaaac tattatcatt
     3661 gaaagaatga gttataatag aagaaagtaa attatttgaa atttattaat ttaaagtgca
     3721 ttgaggagaa aactatgcct atcagtaatg taattttaaa gttagaggag agtgcgtcgc
     3781 actatcctaa aaaaactgcc atttatggaa taaataaaaa ctttacatac gaggaagtac
     3841 aacgtatcac aagttttttt tctaattatc taggaaaaat agttggaaaa aataaaaata
     3901 taggattaat tttggaacat aatgaaaata ttattatttc atttttttca atactaaagt
     3961 ccaacaatac ctatgttccg tttagtacaa agactaattt taatagaatt aaagatagta
     4021 ttgacgattt gaatataaat tatctgatta cagataatta caatttttct actatacaag
     4081 aagaatttaa agggaattac attattaata tagatgatta tcttgatatt agccaaatcc
     4141 cttccaatta taaaaaagaa atagaagata gtgaaactca ggatattgtt tatataatgc
     4201 atacctcagg gagtactgga aaacctaagg gggttaaggt aacggtaaat aacttgaatt
     4261 acattacaga aaatgttcaa agaataactc cttgtgatga agattcgact ctactattta
     4321 tgactccgta tacttttgat gtttcaatta ctgaaatatg tgggtgggtt tataatggtg
     4381 gcgcagtagt ttgtagggat ttaaattcaa atacttggtt tgatgatata agagaagtac
     4441 tatacaaata taatattacg catgttgccg catgcccttc tgtattttta actatgatga
     4501 atatatactc aaatgaaata aatatattta acaatttgaa atttgtggta cttgcgggtg
     4561 aacgatttag tttaaatatc cataaggttt ggaaagaaag taattggtcg tttcgattat
     4621 tcaatgcgta tggtcccact gagacaaccg tttattgtac tttatatgaa ttatcaaaag
     4681 aaagcagcta tgatgaaatt ccaattggga cacctttgca aggtgttgaa tatattatag
     4741 atgagaatac ttcggaatta ttggtcagtg gtcagtgtat aactaatggc tatttagatt
     4801 atgaaaacac aagtaaatat tttataaatg taaatgattg cctatactat aagacaggag
     4861 acttagttga attaaatggt ggattattat attttaaagg taggaatgat aagcaaatac
     4921 aattaaatgg aatgagagta gaattaggtg agattgaaaa tagaattgaa gaaattgaat
     4981 atgtagatca atcaaaagtt atttataaaa ataacaaaat tatagcattt atcaagacaa
     5041 aatattttga tgaagaatat tttaaaaatt attttagtca aaattttgag aaacatctga
     5101 tacctaataa ttttcattta gtgtctgaat ttcctttaaa tcagagtaaa aaagtcgata
     5161 aagataggtt aatgtataat tttttagata ccgaagaatc tgatagtatg ttaaatgaac
     5221 tagaactaga aatcaaagat ttatttgaaa atgttataac tattggtaaa gaaaaaataa
     5281 ccaaaaattc taattttttt aatttaggtg gagactcgtt gtcgtcagtt ttacttttga
     5341 tgggacttga agaaagattt aacatttcaa ttactttgag tgatatctat aattatccga
     5401 cgataatgca actgagtaaa tatatagatt ctttaaagaa gaataaaaat atagatgatg
     5461 aaccaaagaa gaatgagaac attaaaattg acatcaatac tatgactgca gaattgaaaa
     5521 atgttgagaa ttatatttat cgaagtggtc agattgtaag taagtatgag acattacatt
     5581 tacaaagagt atattattat gataactttg aaagttttat tgaatttgaa tatgtttttc
     5641 aaaaaggaga agcgtttgaa gtagttgtag gtctaataaa tgatttaatt gctaacgtaa
     5701 ctatgttacg aactagtttt gtttttgaag atgacaagtt atattttgta gaaaaagcaa
     5761 tggaaaattt ggacagtatg ccaatatttg atgtttcata tcaatctatc gactacatta
     5821 gcgatataaa gaaaaatatc agaatgattt tgatggacag tagaaaagaa ggaggtttac
     5881 taaattcttt aattttatta aaaaatgata agcaatatac tctgatcggt cttatggacc
     5941 attcaattgc tgatgcctca actccagcta caatattgga aattattagt aacctaaaga
     6001 atggaaaaaa aatcaatttt gaatcaactt atgaagatta tattaagcta attcataaaa
     6061 acaataatat gtatgaaata atgaaaagtt ctttttatca ggatttagtt aaatgcgggg
     6121 aagattcaga atttgagatt aaaaagatgg agagtagttt gaatgtttac aaagttgatt
     6181 tagaatctga tgcgaaatca ttaagtactc aacaaatcaa tttattttta gcatataata
     6241 tcggtcaata tcttcttaaa cttttcaatc aacatagtat tgttataaaa tgccttgcta
     6301 atggaaaaga ctatttaggc actaaatata agtacacgct tggagatttt catacaagca
     6361 tttatattgt tgtttataaa gacgaaaatt atttagatta taagaaacgt gtggaggata
     6421 gtataaaaac aaattatgta gaaaaagtat tcaggcctgc atatgtgtat ggtagcaatt
     6481 atcctattaa aaataatgat caaaaacttc taaaaaatag tttaaggcat acaacaaata
     6541 cctctataga ttttttaggt ataattaaag aagatgattt ggagagatat actaaatctg
     6601 taaaacagtc tctatatcag ctaactcaga ttgatgatac tttatatgtt actgtttatc
     6661 tagtaaataa tcaattagtt atctatacaa ataaggattt tttagatttt gagacttttg
     6721 ttaaacttta aagaaaaaaa tttattgcta atagaagaga tttagaaact ccaaaatata
     6781 atgagatata actctagcaa tcttgtaaaa tcaattttct taatttaaaa aaattaattt
     6841 ttagaggcgc caagtagaaa tgcatcttgc aatattagat agcaaattat atacataaac
     6901 gaggaaagag tagaatgaaa attttattaa acaaatacac tccaacacta gccaagttaa
     6961 attatttagc agatcaagat gcaattgtaa ttgctccgct tgatacgcag aaaaaatatg
     7021 aaaaatacct tatgaaaggt aatagattac caaaaataat atatttagaa gactatacat
     7081 taccaaagat gatttcaatt atcagagaat ctattgatgt ggatagtata gaggaagttt
     7141 taacacttga tgagcattat atgtggcatg cgggttttct aaacgattac ttcaagaaaa
     7201 aaaattcatc atatttagtt aattcattgt ttcaggataa atatttaatg agatctgtac
     7261 tgtttgagat agtacctcag cctatgtttc gtcttattga gacgcaaaaa gatatcgaat
     7321 tattttggaa aaatacagca ggagataaat ctataattaa acctcgattt ggagcagctt
     7381 gtgttgggat aaaaaaatat tctagaggtg aacaaattcc ggagaagttc attaattctc
     7441 agtatattat tgaagagtac gtagatttac aaaaaatgct gacttgtgat ggttattcgc
     7501 aaggtagtaa tataatcaga ttttactcac atgaatatga agaattatta ttgggaacaa
     7561 ttggaactag tgatgaattc acagtcagaa cgaatagtct ctatgaaaaa aatatcccct
     7621 ttttacgaaa aatatttagt gaatgtagca aagttcttaa agaatttgtt aatgactact
     7681 caattattcc ttttcacttt gaatggtttt ttgatgagaa caagggggaa tttgtatttt
     7741 gtgaagtagg aaaaagattt ggtggaggcg atattccaaa tttaattcaa agaagttttg
     7801 gtgttaacat ttttgaagaa ttttggggaa atgtctttga taataaagag ctacatccaa
     7861 gtactgattt agaacgtcct aaatttattt ctgctacata ttgtccatat aaaaaacgag
     7921 gaaaactagt ttcggctcct gatatggaat tatttgaatg gactgatgag atatatgtat
     7981 tttcaaaagt aggagaggag tcagatggta taacttctgt agtagaagga gattttattg
     8041 caattattgt aagtgagacc gaggaacaac ataatcaaaa attgtctaaa ctacgggaac
     8101 tatctgagca gtttatatgg gaggaacgtt ttgaaagacg ttaagaaaaa gaatatttta
     8161 tacttagtta gtagtaaagg ggtgtctcgt ataggagata ctatgtttga ttttgctaac
     8221 aatacatttc ttgctgggat taatccaact tcactatcat tagttgcagt atatcagtcg
     8281 ctagaaagtg tgataggtgt tctatttaat ttatttggtg gtgtatttgc ggatagtttt
     8341 aaaagaaaaa aaattattat tgctacaaat atcttgtgtg gtattgcttg cttagtactt
     8401 tcattcatat cacaagatca atggttggtt tatgcaattg tactaactaa tgtaattttg
     8461 gcattcatga gtactttttc tggaccatct tataaagctt ttacgaaaga aattgtaaaa
     8521 aaggatagta tatcacaact taattcattg ctagagacaa caagtactgt aattaaagta
     8581 acaattccta tggtggcaat ttttttatat aagctacttg ggatacatgg tgtgttacta
     8641 ttggatggat tgtcgtttct aatagctgct ttactaattt tctttattgt acctattaat
     8701 gaagcagtgg tcacaaagga gaaaatgaca ttcagaggaa tcattaatga tttaaaaatt
     8761 ggatttaagt atgtttacaa tcataagtca atctttatta ttatcgtact ttctgcactt
     8821 gttaattttt ttctagctgc ttataattta ttattgccct atagtaatca aatgtttgga
     8881 gaaatttcaa ctggacttta tggcaccttt ttaacagcgg aagcaatcgg cggatttatt
     8941 ggagcaatat taagtagttt tgtgaataaa aagttatcaa gtaagaaatt aatgttgttt
     9001 ctatctttat caggactagt gttaatgtta gctactccat tttatattat gtttcataat
     9061 gtaattattt tagctatttc tccagcactt tttagtttat ttctttctat ctttaatatt
     9121 cagtttttct ctattgttca aagagatgtc gataacgaat ttttagggag agtgtttggt
     9181 attatattca cagtagctat tctttttatg cctattggta ctggtttttt ttcggtagta
     9241 ttaaatccta ataatacttt taatcttttt attattggtg cgtctattac agtattatcg
     9301 ctggtatttg gaatactatt taaaagatat aatatgagtt gaaatatatt actaagcgaa
     9361 aataagtaag aaattacctc aaaagaaaat aaaagcacag acctaatata aactgcaccc
     9421 caaaagttag acagaaaaat cggctctttt ctaccatttg tcaagtctat caaggcttta
     9481 agtaaaaaaa tgagctaaga cagtagctat tatgggctct ttgtcaactg tattgggtga
     9541 cgaaaagcta acatctagag aggacccgat aggtcctctc agattgaaga caaagtcctc
     9601 agaagttata cttctgggga cttttcttgc ttcgaaggag tataataaaa gaaaaggtat
     9661 ttgatgaggt actcctatgt ttcacaaaga taatcctgaa tataatcatc gtcaaatagg
     9721 tttctataca cttgatgaac ttgtgtctaa agaccatttt ctaagaaaag ttgaagaaac
     9781 gattgatttt tcttttattt atgatgttgt tgaggatagt tattcttcag ataatggtcg
     9841 ccctagtcta gatcctgttt tgttagttaa gattcctttg attcaatgtt tttagggcat
     9901 tcgttctatg cgccaaacca tcaaggatat cgaggtgaat acggcttatc gttggtttct
     9961 tggattatct ctggatgata aggtaccaca ttttacaact tacggtaaga actatagccg
    10021 acgctttcaa aataaagaat tgttagcaca catttttagt catgtgcttc atcacgtttt
    10081 ggaggcgggg ctcattgatc cctcagaaat cttcatcgat gggacacata tcaagacagc
    10141 tgctaataat cataagtaca aaaatgttgt ggttgatcaa aaagctaaat tcatgagtga
    10201 acaactggaa attgagatta atatagatag gagaaaacac gcaaaaaagt tcttaaagcc
    10261 cgccaaaaaa ggcgaagcta aacctaagaa acaatcaatg acagatccag acagtggttg
    10321 gtttcacaag ggagagcaca aggaagtctt cgcttacaat gcccaggtag cttgtgataa
    10381 acatggttgt gccttggctt atacagttga agcaggcaac atccatgata gtcaggtctt
    10441 ccctgctttt tttgccaagt tagaatcctt ctcacctgaa ttcattattg cggattcagg
    10501 ctacaaaaca cctagtatcg ccaagtttct tttggaaaaa gggattacac cagttttccc
    10561 ttacactaga ccaagaggta agaaagattt tttacgtcca aaagactttg tctatgacga
    10621 acattttgac tgctatcttt gtccagagaa caagatatta acttatcgta taatgacacg
    10681 tgaaggttat cgagagtata aaagttatcc taaaatttgt aagacctgtc ccttgttagc
    10741 gatttgtact gaaagtcgtc agcaccaaaa agttgttgtg cgtcatattt ggaaagatgc
    10801 cctagaagtc tgtgaagata ttcgctatca aagtgggatg aaggaactgt atcaacactg
    10861 taaagaaatg atagaacgcc tattcagaac agccaaaaaa tatcataact tacgttatac
    10921 cagagaagaa ggagagttct gttattttaa atgtatcaag attgttgagg gattaagtca
    10981 aaatataaaa agacaaacat caaaagaatg tttgtcttta ctttagccct acatgagaaa
    11041 gggtggccct gacttataaa ctacggcaga aatatattac atatgtttat atagaattaa
    11101 tttgagaggt aaggtagtac tgaaagatag taaagtaact cacaatttac tcagtattct
    11161 gataaataat tcttttaact tttctaagtc ttcatggact gtcccgtcca tatagagatt
    11221 ataaacttca tcgtcttgtt ccactcgtat ctgtgcagag taaccttttg atagagctaa
    11281 agcacgaata acctctcgtt gagttcgtcc attaccctct cggaagggat gaaaataatt
    11341 aagattatca agaatttctg ttaaatgcat aatgatttca tctttggagt tggcagtttg
    11401 atgataggaa tgaatcagat gattcatatg agtttcagct gtattaaatg actgtattgg
    11461 cataaaagga ttaccgcttt tagagatatt taccttacga tattgtccag cccaagcgta
    11521 aacatcttga aataaatagt tgtgaatggc tagaatatcg ctcatggaat aaacttgaat
    11581 gggctctaaa cgcaagtctg caagccttct agtaacgaat aagtgttcat ttcggtaagc
    11641 ttcttcgata tttgtaatat tttgtttatt gactaagact gtagaatctg gataggtata
    11701 ttggttatta gggtcaatgt acttatatcc ttcatattga ttcttaacca atgttcaatt
    11761 cctttcgtct gttggtgaca taagttttta aatcaattac atcctgaaca gtaggctcat
    11821 aattttcaat cattgaagat ccgatagcat accaaacggt atcaaaatct gaataattat
    11881 caaaagaaat tcctaaaatt gttaattctt cttcatttac atcaagagtc atggcatacc
    11941 tccttgtata tcaatatcat tgtaccataa accctttata tttacatgaa agatggagat
    12001 agttatgatt gattgaactt atgataggat attttcatca taaaaaacga aatgatagaa
    12061 gggatagtat ggaatcagat ataatccata ataggatgat ttgatttgtg attaattctc
    12121 aaagatttac ttgaatgata aaaaaatgat ctaatctcaa tagactttta gtattgatag
    12181 ttactacgcg atactgtcaa taattatgtg taaacactca agtagagttg aagaatgtta
    12241 atcaaataag ctttcaagtg tgtcagcaca ttagccaaac cctttatgga tgcgttgatt
    12301 ttgcttgaaa ttataatctt caaacagggt aactaaataa cgttccagag cctcctcgtt
    12361 aggaaaaaga accttctttt tcgtttgacg tttgatttct
//
