LOCUS       c00070_gnlPro..        13939 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BHDKMDBO_71.
ACCESSION   c00070_gnlPro..
VERSION     c00070_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 17:44:28
            Original ID  :: gnl|Prokka|BHDKMDBO_71
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13939
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13939
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[890:11513]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      891..11513
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..13939
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13939
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(3..119)
                     /locus_tag="ctg70_1"
                     /transl_table=11
                     /translation="VGDEKLISREGRIGPLFMNVQSDEDTLLKVDKVSKTEAQ"
     CDS             complement(156..875)
                     /locus_tag="ctg70_2"
                     /transl_table=11
                     /translation="MSEAIKLFQYNTLGALMAGLYGGTLTVGELLEHGDLGLGTLDSID
                     GELIVLDGKAYQAKGSEGKVEVVEVSPDEKVPYAAVVPHQAEVIFRQRYEMTDKELEDR
                     IESYYDGVNLFRSIKIKGHFKHMHVRMIPKSNADIKFADVATRQPEYEVDDISGTIVGI
                     WTPEMFHGVSVAGYHLHFISDDLTFGGHVMDFVIENGIIEVGPVDQLDQRFPVQDRQYL
                     FAKFNVDEMRKDITKAE"
     CDS             complement(891..2567)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.9e-47, bitscore:
                     149.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEEKQLYGADLVVDSLINHDVEYVFGIPGAKIDRVFDTLEDKGP
                     ELIVARHEQNAAFMAQGVGRITGKPGVVLVTSGPGVSNLATGLVTATDEGDPVLAIGGQ
                     VKRADLLKRAHQSMNNVAMLEPITKYAAEVHDANTLSETVANAYRHAKSGKPGASFISI
                     PQDVTDAPVSVKAIKPMTDPKLGSASVSDINYLAQAIKNAVLPVFLLGNGASSEAVTYS
                     IRQILKHVKLPVVETFQGAGIVSRDLEEDTFFGRVGLFRNQPGDMLLKKSDLVIAIGYD
                     PIEYEARNWNAEISARIIVIDVEPAEVDTYFQPERELIGNVEASLNLLLPAIQGYKLPE
                     GSVEYLKGLKNNVVEDVKFDRQPDEGTVHPLDLIEVLQEQTDDDMTVTVDVGSHYIWMA
                     RYFKSYEPRHLLFSNGMQTLGVALPWAISAALVRPKTKVISVSGDGGFLFSAQELETAV
                     RLKLPIVHIIWNDGHYNMVEFQEEMKYGRSSGVDFGPVDFVKYAESFGAKGYRATSKAA
                     FASLLQEALTQAVDGPVLIDVPIDYKDNIKLGETILPDEFY"
     CDS             complement(2821..3993)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg70_4"
                     /sec_met_domain="MFS_1 (E-value: 4.7e-12, bitscore: 35.5,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKIKKYAALSIYFNRFSSLISEYGYTILINILLSRISVQLVMYFW
                     VVKCLAAIVTNRINISNSKLSRKYLLILLEITKAILLFLLGFGLNHIIVLLVVFIIEVV
                     NVLFSSLLYSCVPIIIDKDSLIKFNARYTSIGSVSYFLAPLFVGLFINKSHFLLFAVYA
                     LLLIVGATSLLFLPNISTLNLKEERKKQNLNITLFNILRSKKIALVLLSGVIVGSIGVV
                     YDTYEVVYLTKYLGISDSMYSFSLSFLAVSFLVMSFLLSFVKQISSHMKAFALGLSFYV
                     LYLLLFSTSSNIYTVLMSYVFLAIGQTMMGIIETNYFQLSLNMKELQKLYIYSETLHSV
                     FSGIAVLVIGSFAFLSSHLVLVFRSLAVFALFILLCYCVFVNLKKLSIDK"
     CDS             complement(4000..4743)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg70_5"
                     /sec_met_domain="Arginase (E-value: 4.2e-34, bitscore:
                     108.3, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILSIIYDGGSRIPGARFAPTKYYQEAMLYDRKDSDIITINLGN
                     QDLFSIDLESLSRTIAESKVQIALGGDHSVTYLLAKATVREGAYLIVLDAHLDYFKDFE
                     SVVKNWNFLSFLTDIFEKIIIIGERNFEFPSSFDNKIIILSMEEYWLNKSRVLKKLDSY
                     IDESKDIYLSIDIDVLDPSVFDSVSYPIIGGFQMNDFLGIISKILCSDKVYFCDIVEYN
                     PMVGSDNAHIFYQMIQFVKSKLRRI"
     CDS             complement(4740..5837)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg70_6"
                     /sec_met_domain="Radical_SAM (E-value: 1.7e-22, bitscore:
                     70.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYQFSLKKFSDSKSQVIKNVIDFLNNNEISLSKTNTKIVEFSTKI
                     PLKVIQIEVTNKCNLRCMHCYLPDYSKELDRKKISSIVYEAKQLGVMDVDFTGGEPLLL
                     QGLSEIIEEVLKEGMCTTIFTNAVYIPEDFKILIQRYDGIRLKVSLDGWNETIHDSIRG
                     RGTFKRTIKNIEYFRSLGVPVTVNVVLNNKNISGVKYFLELFDRLDVKYAFDRFLPFER
                     NNRLSISDEEFNNAILCIPNIQANCNNISESTFESFYCGAGNSYVFINSSGDVGFCPTL
                     SSTKFCGGNINEKTLNDIWINSKFFNHIRNVRCKYYNECPANYVCQGGCRSRAQFFGGS
                     IGSPDIQECKLAYNLTGIKPKSMSL"
     CDS             complement(6039..6188)
                     /locus_tag="ctg70_7"
                     /transl_table=11
                     /translation="MQVSDAIAQIELAEEEVVSSGLSIDIMEIKPSVATELIDGLKGRC
                     PPSV"
     CDS             complement(6248..7048)
                     /locus_tag="ctg70_8"
                     /transl_table=11
                     /translation="MRIIKFPEQISEDIIHYTFLDDIISYNCEKCRGSYCHVNNSLLLD
                     AKTASFLKRTYLKDFIVSDDSVSLLSCGKKCWFHSELGCTINDLGLNKPLTCELYPFHI
                     KKIQNFYIVSFTPCPTFQLNLGEGQRYKDIEDVVLRYIKTGVPVFSPSLHVSEERLKYE
                     IEYQNNFKNTLSEYYRTKTADGTTEFKEYEKWYIYYLDFRWGSIPLSYTSSQANQFWNL
                     YKRVCEDVYKKISYIRTDNIYFIIANQFNKTISKHFQLNFIDKE"
     CDS             complement(7108..7965)
                     /locus_tag="ctg70_9"
                     /transl_table=11
                     /translation="MKDYGKLFKKFRESRGLVLKDIAKLGVSVSHISRFERENTDLTIS
                     KFMSALNAINMPIDEFMYAANDFQRDEFNEILEKISLFVSARNVSGMEKLLISQVEKIE
                     KRETFYTLNTILIKIRLQDLSDKSYYDESDIQYLSDYLFSVEYWGCYELLLFANTVDVL
                     NHQTMMLLSREMCKRSEFYKDLPNYRRLHSTMLLNCYIISIERDEYIDALYFEKQLNHS
                     CFTETEIYEKLVFHYSKNLYELKKNRSNKAILEMKKCITAMKLANSENLAIKFENHLSG
                     VLKM"
     CDS             complement(8488..10320)
                     /locus_tag="ctg70_10"
                     /transl_table=11
                     /translation="MPNIEELKQRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAA
                     CEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGL
                     DASEAVLASAKAGIGIEEILEQIVEKVPAPQGDVEAPLQALIFDSVYDAYRGVILQVRV
                     VNGMVKTGDKIQMMSNGKTFDVTEVGIFTPKAVGRDYLATGDVGYVAASIKTVADTRVG
                     DTVTLADNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPET
                     SQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSE
                     FPDPTRIDAIEEPYVKAQIMVPQEYVGAVMELAQRKRGDFETMEYIDDNRVNVIYQIPL
                     AEIVFDFFDKLKSSTRGYASFDYELSEYRRSQLVKMDILLNGDKVDALSFIVHREFAYE
                     RGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARTDIKALRKNVLAKCYGGDVSRKRKLL
                     EKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDEK"
     CDS             complement(10708..10854)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: adh_short_C2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_11"
                     /sec_met_domain="adh_short_C2 (E-value: 1.9e-15, bitscore:
                     47.1, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTFAKDITLKRLSEPEDVAAAVSFLAGPDSNYITGQTIIVDGGM
                     QFH"
     CDS             complement(11130..11513)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: adh_short"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_12"
                     /sec_met_domain="adh_short (E-value: 1.8e-32, bitscore:
                     102.4, seeds: 44, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VVKLVTTIGRGGFRMSKVAIVTGAGQGIGFAISKRLVEDGVKVGV
                     LDYDAETAEKAVAELSEDKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVAPT
                     KSLDTITEEQFQRTFNINIGGVI"
     CDS             complement(11682..11975)
                     /locus_tag="ctg70_13"
                     /transl_table=11
                     /translation="MDIAQIQSELAQDGLLIDVRTPEEYAEGHVKDALLIPHTQFFTAD
                     IPAKKDASIYLYCKMGSRAEFAAGVLKERGYTKVTTLGGLGDMEALGFKFEK"
     CDS             complement(11977..12405)
                     /locus_tag="ctg70_14"
                     /transl_table=11
                     /translation="MKVGNMQKTFFIIKPDAVKRHLIGQVLDRIERRGFVIERMEMLML
                     DEERLKEHYAQLADKPFFPSISEFMMSGPAVIGIMSGPGVIKSWRDMMGATNPGDAAPG
                     TIRGDFATAPDGDMIPNIVHGSDSEESAAREIKIWFGE"
     CDS             12716..13507
                     /locus_tag="ctg70_15"
                     /transl_table=11
                     /translation="VADQKANGIDILTDGKFGRSMWHLDFVWGLKGIERYIAEHGYTFK
                     DHDGGQYETRKDIGIRITEPLSGKNHHYLDIYKLVKAEAGDEDTKQTIWGPAHAYTELA
                     IFDRLAVPGQVYETNEELKKGLINAYKEFLDEYKAVGGKIVQFDDCLWELFDPSNPTSF
                     YSYGNGDLAELADEFVAINNEVVDYTHELGLTVWTHNCRGNYEIRSASEGTYEDIAKKF
                     LAEQHYDRFFLEWDSDTAGDIKALEALKDSKAEVVFGLLSS"
     CDS             complement(13772..13939)
                     /locus_tag="ctg70_16"
                     /transl_table=11
                     /translation="LPYYVTHAETKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERA
                     LKDLQTFIDA"
ORIGIN
        1 gtttgggctt cggttttaga aactttatca actttaagaa gcgtgtcttc atcactctga
       61 acattcataa aaagaggacc tatccggccc tctctagata ttagcttttc gtcacccact
      121 atagttgaca aagagacagt atcttattta tatgcttatt cagccttagt aatatcttta
      181 cgcatttcat caacattgaa tttagcaaag agatattgac ggtcttgaac tgggaagcgt
      241 tgatcgagtt ggtcaactgg tccaacttca ataataccat tctcgataac aaagtccata
      301 acgtgaccac cgaatgtcaa gtcatctgaa ataaaatgga gatggtaacc agcaacactc
      361 acaccgtgga acatttcagg tgtccagata ccaacgattg tacctgaaat atcatctacc
      421 tcatactcag gttggcgagt ggcaacatca gcaaacttaa tgtccgcatt tgattttgga
      481 atcatgcgca cgtgcatgtg tttaaaatga cctttgattt tgattgaacg gaaaagattg
      541 accccatcat agtatgattc aatacgatcc tcaagttctt tatcagtcat ttcataacgt
      601 tgacggaaga taacttcagc ttggtgaggt acgactgctg catagggaac tttttcatca
      661 ggagaaactt ctaccacttc gactttacct tcagagcctt tagcttggta ggctttaccg
      721 tcaagaacaa tcaactcacc atcgatagaa tctaatgttc cgagacccaa gtctccatgc
      781 tctaacaact ctccaacggt taaagtacct ccataaagcc cagccatcaa ggctcccaaa
      841 gtattatatt gaaataattt tatggcttca gacatgtcta caccctcttt ttagtaaaat
      901 tcatctggca aaatagtttc gccgagttta atgttatctt tatagtcaat tggaacatca
      961 ataaggactg gtccatctac agcctgagtc aaagcctctt gaagcaagct agcaaatgct
     1021 gctttacttg ttgcacgata acctttggct ccaaagctct cagcatattt tacaaaatct
     1081 acaggaccaa agtcaacccc agatgaacga ccgtacttca tttcttcctg gaattccacc
     1141 atattgtaat gaccatcgtt ccagataata tggacaattg gcaatttcaa acgaactgct
     1201 gtttccaatt cttgtgctga gaagaggaaa ccaccatcac cagaaacaga aatcactttt
     1261 gtcttaggac gaaccaaagc tgcagagata gcccatggaa gagcaacacc tagcgtttgc
     1321 atcccatttg agaaaagcaa atgacgtggt tcatacgatt tgaaataacg tgccatccaa
     1381 atatagtgac taccaacatc aaccgtaaca gtcatatcat catctgtttg ttcttgcaaa
     1441 acttcgatta aatctagcgg atgcaccgta ccttcatcag gctgacggtc aaacttaaca
     1501 tcctcaacaa cattgttttt caaaccttta agatattcaa ccgaaccttc aggcaattta
     1561 taaccttgaa tagcgggcaa aagcaagttt aagctcgctt ctacattacc aatcaattca
     1621 cgttccggtt ggaagtaagt gtccacctcg gccggctcaa catcaataac gatgatacgt
     1681 gctgaaattt cagcattcca gttacgtgct tcatattcga ttgggtcata accaatggca
     1741 ataactaagt cggatttttt aagcaacatg tctccgggtt ggttacggaa aagacctaca
     1801 cgaccaaaga aagtatcttc ttcaaggtca cgtgacacga taccggcacc ttggaaagtt
     1861 tcaacaactg gcaatttaac atgcttcaaa atttggcgaa tagagtaagt tacggcttct
     1921 gatgaggcac cattccccaa aagaaagact ggcaacactg catttttaat ggcttgtgcg
     1981 agatagttaa tatcagaaac agatgctgaa ccaagttttg gatctgtcat aggcttaata
     2041 gccttaacac tgaccggagc atccgtcacg tcttgaggaa ttgaaatgaa gcttgcacct
     2101 ggtttccctg acttagcgtg acgataggca ttagcaaccg tttcagaaag ggtgttagca
     2161 tcatgtactt cagcagcata tttggtaatt ggctcaagca tagcaacgtt attcattgat
     2221 tggtgggcac gtttcaagag atctgcacgc ttaacctgac caccaatagc aagaacaggg
     2281 tctccttcat ccgtcgctgt taccaaacca gtagccaaat tggagacacc tggaccagat
     2341 gttaccaata ctacacctgg tttcccagta atacgtccaa caccttgagc cataaaagca
     2401 gcattttgct catgacgggc aacaatcaat tcaggtccct tatcttccaa ggtatcaaaa
     2461 accctatcga tttttgcgcc tggaatccca aagacatact caacatcatg gttgatcaaa
     2521 ctatcaacca ctaaatctgc accatacaat tgcttttctt ctgacatgaa cacagtcctt
     2581 ctagccctaa aatggtagag ccaactttcc tttcaagtat aagtcacaaa gtgtcaaagt
     2641 ctgctcgttt tttcacaaac tttcatcaat tcacaattct gttatcatta tagcacagtt
     2701 ttcagacaat cttgtgaaaa aaggcagact aggtgactaa aaaaagacaa acactcaaaa
     2761 tagcgtttgt ctactttata aattaactat ctcatttgct tgttttctga tttataaata
     2821 ttacttatca atgcttagtt ttttgaggtt tacaaacaca caataacaca gaagaataaa
     2881 cagagcaaaa acagcaagac ttctgaaaac taaaacaaga tgactactta aaaaggcaaa
     2941 acttcctatt actaaaacag caatgcctga aaatacagaa tgtaaggtct ccgagtaaat
     3001 atatagtttc tgtaattctt tcatgttaag tgacaactga aaataattgg tttcgattat
     3061 ccccatcatt gtctgaccta tcgctagaaa aacataactc attagtactg tataaatgtt
     3121 cgaagatgta ctaaataaaa gtagatatag aacataaaat gaaagaccta aggcgaaagc
     3181 tttcatatga gaacttattt gtttcacgaa gctaagaagg aagctcatta ctaagaatga
     3241 aactgctaaa aatgataagg aaaaggaata catagaatca ctaataccga gatactttgt
     3301 taaataaaca acttcataag tatcataaac aactccaatt gatcccacaa taactccaga
     3361 taatagaact aatgcaattt ttttggatct cagaatgtta aataatgtaa tgtttaaatt
     3421 ttgttttttt ctttcttctt tcaaatttaa agtcgaaata tttggtaaaa ataaaagact
     3481 agtagctccc actatcaaaa gaagagcata aactgcaaac aataaaaagt gacttttatt
     3541 aataaataaa ccaacaaaca acggtgctaa aaaataagat actgaaccaa tgcttgtata
     3601 cctagcgtta aacttaatca atgaatcctt gtctataata attggtacac aactatataa
     3661 taaactggaa aacaatacat tgacaacctc aattatgaat acaactaata ggacaattat
     3721 atggtttaat ccaaaaccta gtaagaaaag taagattgcc tttgtaattt ctaacagaat
     3781 aagcaggtat tttctgctca gtttactatt tgagatatta atcctatttg taactattgc
     3841 agctaaacac tttaccaccc aaaaatacat aactaattgc acagaaattc tagacaatag
     3901 aatgttgatc aagatagtat aaccatactc tgagattaac gatgagaaac gattaaaata
     3961 aatactcaat gctgcatatt tttttatttt caatatttcc tatatcctcc ttaattttga
     4021 tttaacaaat tgaatcattt ggtaaaaaat gtgagcatta tcacttccaa ccatcggatt
     4081 gtactcaact atatcacaaa aatatacctt atcagaacat aaaattttgg aaattattcc
     4141 aagaaaatcg ttcatttgaa atcctccaat aataggatat gatactgaat caaaaacaga
     4201 tggatccaaa acatcaatgt ctattgataa gtaaatatct tttgactcat caatataact
     4261 atctaacttt ttcaaaactc tactcttatt taaccaatac tcctccattg agaggatgat
     4321 tattttatta tcaaatgaac taggaaactc aaaattcctt tccccaatga taattatttt
     4381 ttcaaaaata tcggttaaaa aacttaaaaa attccaattt tttacaacac tttcaaagtc
     4441 tttgaagtaa tctaaatgag catctaaaac aattaaatat gctccctctc gaacagtggc
     4501 ctttgctaat agataagtaa ctgaatgatc tcctcctaaa gcaatctgaa ctttagattc
     4561 agcaatagtt cgacttagac tttctaaatc aatagaaaat aaatcttgat tacctaaatt
     4621 aattgtaatt atatcagaat ctttcctatc atataacatc gcttcttgat aatattttgt
     4681 gggagcaaat ctcgctcctg gaattctact tccaccatca taaataatag ataatatttt
     4741 cataaactca ttgactttgg cttaatccca gttaaattat atgctaactt gcactcctgt
     4801 atatcgggac tcccaataga acctccgaaa aactgagctc gacttctaca cccaccttga
     4861 caaacataat ttgcagggca ttcattataa tacttacatc gtacatttcg aatatgattg
     4921 aagaacttcg aattaatcca aatatcattt aaagtctttt cattaatgtt acctccacaa
     4981 aatttagtgg aggataatgt cggacaaaat ccaacatcac ctgacgaatt tataaacaca
     5041 taagaattgc cagcaccaca ataaaatgat tcaaatgtgg attcggatat attattacaa
     5101 tttgcttgaa tattgggaat acacaaaata gcattattga attcttcatc actaattgat
     5161 agtcgattat tcctttcaaa aggtaaaaac ctatcaaaag catatttcac atctaatcga
     5221 tcaaacaact ccaaaaaata cttcactcca ctaatattct tgttattcaa aacaacatta
     5281 acagtaacag gtactcctaa actcctaaaa tattcaatat tcttaattgt tctcttaaat
     5341 gtacctcttc ctctaattga atcatgtatt gtttcattcc aaccatctaa actaactttt
     5401 agtcttatac catcatatct ttgaatcaat attttaaaat cttcaggaat atatacagca
     5461 tttgtaaaaa ttgttgtaca cattccctct tttaatactt cctcgataat ttcacttaat
     5521 ccctgtaata ataatggttc gcctccagtg aaatcaacat ccattactcc tagctgctta
     5581 gcttcatata ctatacttga aattttcttt ctatcgagct cctttgaata atcaggtaaa
     5641 taacaatgca tacatcttag gttacatttg ttcgtgacct caatctgtat cacttttaat
     5701 ggtattttcg ttgaaaattc aacaatttta gtgttggtct tagagagtga tatttcattg
     5761 ttatttagaa aatctataac attttttatt acctgactct ttgaatcaga aaactttttc
     5821 aatgaaaatt ggtacataaa ttttaaagct aaaaatgtag ctaaatttaa tgaaaatagt
     5881 ttattattcc tattattcct gagtattcct tgcttattgt accaattaaa aaaatcgagt
     5941 aaacattgct cgtcatatta attccctgca atcttccaaa aatattaata taaaaaccaa
     6001 aggattagaa atagactcta atcctacaat cagttctatt agacagacgg tgggcaacga
     6061 cctttgagtc catcaatcaa ctctgtagca acagaaggtt taatttccat aatgtcaata
     6121 gatagaccgc tagaaacaac ttcttcttct gctaattcaa tttgtgcaat agcatcacta
     6181 acttgcatcg taatatcctc cattatttat ttaagaatca ataagtaccc ataacaaatc
     6241 atagaaatca ttctttatct ataaaattta gctgaaaatg ctttgaaatt gtcttattaa
     6301 actgatttgc aataataaag tatatgttat ctgttcgtat atatgatatt tttttataaa
     6361 catcttcaca aactctcttg taaagattcc aaaattgatt tgcttgtgaa cttgtataag
     6421 ataagggtat acttccccat ctaaaatcta aataatatat ataccatttt tcatattctt
     6481 taaactctgt agtgccatcg gcagtctttg ttcgataata ctctgataaa gtgtttttaa
     6541 aattgttttg atactcaatc tcatatttca gcctttcctc tgaaacatgc aaagacggac
     6601 taaaaactgg caccccagtt ttaatatatc gtaaaactac atcctctata tccttgtacc
     6661 tctgcccctc accaaggttc agttgaaatg tcggacaagg agtaaaagaa acaatataga
     6721 agttctgaat tttcttaata tgaaaaggat ataattcaca agttaatggc ttgttcaagc
     6781 ctaaatcatt tatcgtacaa cccaattcag aatgaaacca gcacttttta ccacaactca
     6841 acaatgaaac actatcatca ctaacaataa aatctttaag atacgtgcgt tttagaaaac
     6901 ttgctgtctt tgcatcaagt aataaagaat tattcacatg acaataagat cctctacact
     6961 tttcacaatt ataagagata atatcatcta gaaacgtata atgaatgata tcttctgaaa
     7021 tctgttcagg aaatttaata attctcatat caataatata tcatttaatt ttgacactga
     7081 taatttatac catatacaca aatccaacta catttttaac actccagata aatgattttc
     7141 aaattttata gctaaattct cactattagc cagcttcatt gcagtaatac acttcttcat
     7201 ttctagaata gctttattgc tcctattctt ctttaattca tataaatttt ttgaataatg
     7261 aaacactaat ttctcgtaaa tctcagtttc cgtaaaacaa ctatgattta actgtttttc
     7321 aaaatacaac gcatcaatat actcatctct ttcaatactt atgatataac aatttaatag
     7381 cattgttgag tgtaaccttc ggtagtttgg taaatccttg taaaattctg aacgtttaca
     7441 catttctctt gataaaagca tcattgtttg atgattcaat acatctacag tattcgcaaa
     7501 taacagtagt tcgtaacaac cccaatattc tacagagaat aggtagtctg ataaatattg
     7561 gatatcagat tcatcatagt aacttttgtc tgataagtcc tgtaaacgaa tttttattaa
     7621 aatagtattt agagtataaa aagtctcacg cttttcgatt ttttctactt gagagattaa
     7681 taacttttcc atacctgaca cgttccttgc tgaaacaaat aaactaatct tttctaagat
     7741 ttcattaaac tcatctctct gaaagtcgtt tgctgcatac ataaactcat caataggcat
     7801 atttatcgca tttaaagctg acataaactt actaattgtc aaatctgtat tttcacgttc
     7861 aaagcgggaa atatgagata ctgatacgcc taactttgcg atatctttta agactaatcc
     7921 cctagactct ctaaatttct taaataattt tccataatct ttcataaaaa gcacctcttt
     7981 tgcatatacg agaatttccc agataaactt aaaagtatta tatcatatag tgagatagga
     8041 ggttaatttc tatgaataaa gaaagttttt tagctatctt acttctaatt tttgaaagca
     8101 ttattgtaat tgctgttggc taaacaaata gaaaataaag acaccacaaa agttagactt
     8161 tcgatgtcta acttttgtgg tgtagttaag gtatgatgtt gttctctaat aagggtataa
     8221 tataaaaaag actctatgat ttctgtagta ggtaaaacca ctatagagat tatagagctt
     8281 tttgagtgta tacaaaaact agttctttat tggaacaaag tcaacaacta atctagtatt
     8341 ggttgcagcg gcaatttctt ccaatgtttt atatgttgga ttagtggtgc cattctctat
     8401 acgtcacttt gagaaggtaa attttaaaat cctctttatc ataacttttt actaaaatag
     8461 ccagaacatc acattctact atcattctta tttctcatct tcgtccattg aaagcacaga
     8521 caagaaggct tcttgtggta cctccaccga accaatggct ttcatacgtt tcttaccagc
     8581 tttttgtttt tcgaggagtt tacgtttacg tgaaacgtca ccaccgtaac atttagccaa
     8641 gacgttttta cgaagagctt tgatatctgt acgggcaaca attttttgac caatagccgc
     8701 ttggatagga acttcaaatt gttgacgtgg aataattttc ttaagtttat caacgataag
     8761 ttttccacgt tcgtaggcaa attctctatg gacaataaag ctaagggcat cgaccttatc
     8821 accattaagg agaatatcca ttttcaccaa ttgtgaacga cggtactctg acaattcata
     8881 gtcaaaactt gcataaccac gagttgatga cttcaattta tcaaagaagt caaagacgat
     8941 ttcagcaagt ggaatttgat agataacgtt aacacgatta tcatcaatat attccatggt
     9001 ttcaaaatca ccacgtttac gttgcgccaa ctccataaca gcaccaacat actcttgagg
     9061 aaccataatt tgagctttga cataaggctc ttcaatggca tcaatacgtg taggatctgg
     9121 aaattcagat gggttggaca cttcaagcat ttcaccgtca gtagtgttaa catggtaaac
     9181 tactgatggt gcagtcatga tgagatcgat gttaaactca cgttccaaac gctcttggat
     9241 aacatccatg tgaagaaggc ccaagaaacc acaacggaaa ccaaaaccaa gggcttgaga
     9301 cgtttcaggc tcaaattgaa gactggcatc attcaattgg agcttttcaa gagcctcacg
     9361 caagtcgtta tatttatttg actcaattgg ataaagacca gcaaagacca ttgggttcat
     9421 ttgcttataa ccatgaagtg gttctgcggc tggattatcc gcaagtgtca ctgtatcacc
     9481 gacacgagta tccgcaactg tcttaattga agctgctaca taaccaacat ctccagtcgc
     9541 aaggtagtca cggccaacag ctttaggagt gaaaatacca acctcagtaa cgtcaaaggt
     9601 cttgccatta gacatcattt gaatcttatc gcccgtttta accattccgt taaccacacg
     9661 cacttggagt atgacgccac gatacgcatc ataaacagag tcaaagataa gggcttggag
     9721 aggtgcttcc acatcacctt ggggcgcagg aactttctca acaatttgtt cgagaatctc
     9781 ttcgatacca atgccagcct tagctgatgc aagcacagct tccgaggcat ctaatccgat
     9841 aacatcttca atctctgtac gtacacgctc aggatctgcc gctggaaggt cgattttatt
     9901 gataactggt aagatttcca agtcattatc aagtgccaag taaacattgg caagtgtttg
     9961 tgcttcaatc ccttgagctg catctaccac caagatagca ccctcacagg cggcaaggga
    10021 acgtgacacc tcataagtaa agtccacatg tcccggtgtg tcgataaggt ggaaaatata
    10081 agtctcgccg tctttagctt tgtagttaag ctcaatggca ttcagtttga tagtgatacc
    10141 acgttcgcgc tcaagatcca tactatcaag gagttgtgcc tgcatctcac gacttgatac
    10201 agtctcagtc ttttccaaga tacggtcagc aagcgttgat ttaccatggt caatatgagc
    10261 aataatcgag aagttgcgaa tcttctcctg tctttgtttt aattcttcaa tatttggcat
    10321 tttattcttt cctaattctt acttgtgatt gttaaaaaac gaaccgtcac ctcctattat
    10381 acaaaaaaga caggcatttg cctatctcta atatctgctt tatgactgca tttagtcctt
    10441 cttatttctt aaaattatca ttgtagtgct tattaataat agctgaacgc ttgttctcta
    10501 ttgaactact tgaaaatgga gctaaaccaa aggctagtac aataattccc aatagaataa
    10561 gactaaaaaa tgggtgctca gcaatatagt gtaagatgtc tgatatggga atccaccttt
    10621 aaaaacataa ttatttataa ctatattatc agaaacatta tgttttatca agcaaaaaaa
    10681 gagagccatt cgctctccct tttaacctta atggaattgc ataccaccat caacgatgat
    10741 tgtttgacct gtgatgtagt ttgagtcagg tccagctagg aagctaactg ctgctgcaac
    10801 atcttcaggt tctgacaaac gtttgagggt aatatcttta gcaaaagttt gcatacccca
    10861 ctcatcatct ttaccagcat tttaccaact tcgtgggcaa tgtcaaacat cattggagtc
    10921 ttaacgatac ctggtgcata agcatttaca gttatacctg aatcagctaa gtcacgcgcc
    10981 aaagtttgag taataccacg aactacgaat ttagttccac catatacagt taagttagag
    11041 ttccctacga cacctgcttg taaagttgca ttgataattt taccaccatg accaagtgat
    11101 ttaaattgtg cttgggcagc ttgtgcacct cagataactc caccaatatt aatgttaaat
    11161 gtacgttgaa actgttcttc agtaatagtg tcaagggatt ttgttggtgc cacaccagca
    11221 ttattaacaa caacattcaa gtcgccaaag tgatcaacta ctttttggaa agctgctgct
    11281 acctcagctt gtttagacac atctgctaca acggaaaatg ccttgtcttc tgacaactca
    11341 gcaactgctt tttcagcagt ttcagcgtca tagtccaata ccccgacttt aacaccatct
    11401 tcaaccaagc gttttgaaat cgcaaaacca ataccttgac ctgcacctgt aacaatagca
    11461 acttttgaca tacgaaatcc tcctctacca attgtagtca caagcttaac cacaagccct
    11521 atctcaattg gaatatgcta agttaatcaa gttctggcaa agtcattttc ataggctttt
    11581 tcttaactca tttagaatct taccacttta tgaaagcgtt gttaataatt tgtcatgctt
    11641 tttgaaagca aataagatca ccactagtga ccttatgtgt attatttttc aaacttaaac
    11701 cctagtgctt ccatatcacc taggccacct aaggtggtaa ccttagtata tcctcgttct
    11761 ttcagtactc ctgcagcaaa ttcagcacga gatcccattt tacaatagag gtaaatggag
    11821 gcgtcttttt tagctggaat gtcagctgtg aaaaactgcg tgtgaggtat taataaagca
    11881 tccttaacat gaccttctgc gtactcttct ggagtcctga catcaattaa tagtccatcc
    11941 tgagctaatt ctgattgaat ctgtgctata tccatcctac tcaccaaacc aaatcttaat
    12001 ttctcgagcc gcagattctt ctgaatcaga gccatgaacg atatttggaa tcatgtcacc
    12061 atctggtgct gttgcaaagt ctccacgaat cgttccagga gcagcatccc caggattagt
    12121 tgctcccatc atatcacgcc atgacttaat aactcctggg ccggacataa taccaataac
    12181 tgctggacca ctcatcatga attcagaaat actagggaaa aaaggtttat cagccaattg
    12241 ggcataatgt tctttaagac gttcttcgtc aagcatcagc atctccatac gctcaataac
    12301 gaagccacgt cgctcaattc gatcaagcac ttgaccaatt agatgacgtt taacagcatc
    12361 tggtttaata ataaagaatg ttttttgcat attcccaacc ttcatcgttt tctttccatt
    12421 ttatcataag aagtatcatt ttgcagagct aaaccttgta tagtctaaaa ctatatacac
    12481 agcaagaaat taactatttt tcattagttc ccataagaaa taatatagat gtaaatagac
    12541 atttcgaggt aaatttaatg acaaaatcta aattccaatt agtcggttct cttcttcgtc
    12601 ctgcggatct ccgtaaatac aaggacgaaa tcgagcatcg tgacgacatc cagtatcctt
    12661 tctatgatgc ccttcctggt tatcaagaaa ctgaaactgc atctattaag cgaatgtggc
    12721 tgaccaaaaa gctaacggaa ttgacatcct taccgatggg aagtttggac gttctatgtg
    12781 gcacttggac tttgtctggg gactcaaagg tattgaacgc tacattgctg agcatggtta
    12841 tacttttaaa gaccatgatg gtggtcaata tgaaacacgt aaagatatcg gtattcgtat
    12901 cactgagcct ctatcaggta aaaaccacca ctacctagat atttacaaat tggttaaggc
    12961 tgaagctggt gatgaagata ccaaacaaac tatctgggga cctgctcatg cctacactga
    13021 acttgctatc tttgatcgat tggctgttcc tggacaagtc tatgaaacaa acgaagaact
    13081 caaaaaaggt ttgattaatg cctataaaga attcttggat gaatacaagg ctgttggtgg
    13141 taaaatcgtt caatttgacg actgcctctg ggaacttttt gacccatcaa accctacaag
    13201 tttctactca tacggcaatg gtgatttggc agaattggcc gatgaatttg ttgctatcaa
    13261 taatgaggtt gttgactata ctcacgaact tggtttaacg gtttggacac acaactgtcg
    13321 tggtaattat gaaatccgtt ctgcttctga aggaacttac gaagacatcg ctaagaaatt
    13381 cttggcagag caacactatg accgcttctt ccttgaatgg gatagcgata cagctggtga
    13441 tatcaaagct ctggaagccc ttaaagacag taaagctgaa gttgtatttg ggctattgtc
    13501 ttcttaaacg actgacctag atgacgaaga acgtgttctc gatttgcttg aaaaagcgag
    13561 tcaaatcctt ccaaaaaaac gtctcttccc ctttcaccaa tgtggtttcg cctcatgtga
    13621 ctcaggtaat gagctggcaa cacctcaaca atgggctaaa atcaaacaag gtcaagaaat
    13681 cgctaagaaa ttctttggct aatcgatatt tctattcgct cctctctaaa acgaaaagcc
    13741 ttcactcttg tgagggcttt ttatgttagc atcaagcatc tataaaagtt tgcaaatcct
    13801 taagagctct ttctgcgatt ttttcataac gctctttctt gtcacgaata cgtgggcctt
    13861 ctaattcttt gataatacca aagttaacat tcattggttg aaaatgtttg gtttcagcat
    13921 gtgtcacata atatggaag
//
