LOCUS       gnlProkkaCGOFBKHF_211  11936 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CGOFBKHF_211.
ACCESSION   gnlProkkaCGOFBKHF_211
VERSION     gnlProkkaCGOFBKHF_211
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 16:22:09
            Original ID  :: gnl|Prokka|CGOFBKHF_211
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11936
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11936
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[802:1936]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      803..1936
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..11936
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11936
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(3..470)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 58.9; E-value: 9.2e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg210_1"
                     /transl_table=11
                     /translation="MLKVAICDDSDRDASQLEHYLLSYDKFPLETKLYTNPQKLLNQRT
                     PDIHCVFLDINMPGINGIDVAQKIRKFNPFIPIIFVTSYRDYMEQVFEVQTFDYIVKPI
                     EPQKLMKVLDRILRFLDIGQALFTFSFGKHNYSVPSSDIVFFEKDKRSVFIY"
     CDS             803..1936
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg210_2"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 2.3e-13,
                     bitscore: 40.1, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 2e-48, bitscore: 154.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSHCPRIKEIYPIYKLHDNLFRVGSQIGITTEISDEDDKMWSLV
                     NILDGRTINDVVDIMLTKYPDLTEQDIIGAIELLDKEGVIEEGATINCIKERYHSNIYY
                     FSRYLNSFKDSIDIQKRLNETTVLLLGLGGGGSNILTLLSGLGPKKIKIVDFDIIEKSN
                     LGRQFLYKEEDVGALKTQIAHQEVSKMNSDIEVETHNLRITCVNDLLPLLDNVDIVICV
                     IDEPQYDIQRIVNKAVVTKNIPCVFGASQVSRRRVYSVVPHQTGCFDCLNIHYTKIDSL
                     FLEQFRGIRTVTKKIPTIAYGPAMFQLTSAIVDEAVRLITKYAEPMSLNRQYEINYENG
                     ASFTHKPWGHYPDECPTCGNGKEENWEIFSQYGEIKL"
     CDS             1933..2844
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 171; E-value:
                     5.6e-52)"
                     /gene_kind="transport"
                     /locus_tag="ctg210_3"
                     /transl_table=11
                     /translation="MTFETLTIENLTKSFDKQHFANNHIFLELEAAKITALIGHNGAGK
                     STLLKQMIGFIKPDQGDVHYGDISFIHNRKQARTMMSYMSQQYAPLEKLTVEQNLEMIG
                     RMRGLSTSELQKEIEHLLADLEIVEYRDKKGKNLSGGLKRLTSFAMALIGSADIMLLDE
                     PTNDVDPVRREKQWRLLQKLAYKGHTIIIVTHNLLEVEKYADNFALFNHGKLLKSGPVH
                     QMSYKNHYQISFNFVSKEFLSLFEHFTMVNGCVCQMEIEESELTRILIQVKEGIEKGLI
                     SNLSVKMKTLSISDIYKEELVN"
     CDS             2846..3568
                     /locus_tag="ctg210_4"
                     /transl_table=11
                     /translation="MTQFFYLLRWNYLRQKNLFILFTLAQVLLSVSLLFGYPLVIGKMD
                     TTTAYYLASGSVLMGVISIGCTISSPVIANAKSEGHVDYIRALPIPRILISLADLCIWL
                     IAILPGVFFTFLLGCLRFSVQLNLSILSVFVMLLICLTMISLGFSIAYIFSQNIVTLMS
                     QLILMIGLMFSPIMYPAGRLPDWLDQLYFLLPFVPSANLLRASFYRHGTVSLVDIGVLI
                     FWIFLTQLLILGTLQKEL"
     CDS             3757..4740
                     /locus_tag="ctg210_5"
                     /transl_table=11
                     /translation="MAKPIRVLLYYKYVPIENAEQFAADHLAFCKSIGLKGRILVADEG
                     INGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEEEEQAFKKMFVRYKKEIVHLGLEDN
                     NFDSDINPLETTGAYLSPKEFKDALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRE
                     LPQWVRDHKEEFMDKRVVVYCTGGVRCEKFSGWLVREGYKDVGQLHGGIVTYGKDPEVQ
                     GELWDGKLYVFDERIAVDVNRVDPIVVGKDWFDGTPCERYVNCGNPFCNRRILTSEENE
                     DKYLRGCSHECRVHPRNRYVSENDLSQEEVVERLAAIGEGLDVTPA"
     CDS             4919..5116
                     /locus_tag="ctg210_6"
                     /transl_table=11
                     /translation="MAKNLRLKAARAEHDMTQGDLAEAVGATRQTIGLIEAGKYNPSLA
                     LCIAICKTLDRTLDQLFWEI"
     CDS             5130..5624
                     /locus_tag="ctg210_7"
                     /transl_table=11
                     /translation="MMKFKLVNNKVTDEREKALNNKVGAECFYIMIAGTLACLVYSSFF
                     NKGVITSNYLAFPLFIAWIWSIYRSERLSVNTFGGSGMTVLGCLLVTALITLMIMSANY
                     QFNHNVYHNNPLDPRYLMAWPLTYILYIPFVFFMNWALTALGRYERRRLEKQLDDLENE
                     E"
     CDS             5703..6473
                     /locus_tag="ctg210_8"
                     /transl_table=11
                     /translation="MLLTEFDANRQAIINPEALHEPLEGFPKIAVSCFSRLTFQRMLEM
                     FPHELIYEISMANVAIPIYKLVIDDNELAIFNAPVGASACVGILEDIFALGADKLVLFG
                     TCGVLDEDIKETSIIIPSHALRDEGTSFHYVEASDEIAVNVGVLDHFRSYLNERQISHK
                     EGKVWTTDGIYRETNGKLKARKSAGAICVDMECSAVAALAKFRGVDICHFFYAADHLSE
                     GNWDARNLMNHMDLDEKDKIALLALEFACDWIKP"
     CDS             6564..7250
                     /locus_tag="ctg210_9"
                     /transl_table=11
                     /translation="MLEDKNFAERLNILRAGVLGANDGIISIAGVVIGVASATSNIWFI
                     LISALSAIFAGAFSMAGGEYVSVSTQKDTEEAAVAKEQALLDRSPESARESLYQTFLSQ
                     GDCETEAEVKVNQAFSKNPIKVLVEEKYGVDMEEITNPWHAAVSSFLSFSVGSLPPTLA
                     ILLFPDPYRIPITAVVVALTLILTGYVSAKLGKAPVKQAMLRNLAVGLLTMLVTYVVGQ
                     VFHVNV"
     CDS             7330..8049
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1154:Pseudouridine synthase (Score: 201.2; E-value:
                     2.1e-61)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg210_10"
                     /transl_table=11
                     /translation="MRLDKLLGQSGYGSRNQVKKLIRSRQVYVDGVLADRDNLNVDASL
                     QTIMVSGKELEHAPEVYYLMNKPSGVVSARKDKEHQTVIDLIRPEDQREGLYPVGRLDR
                     DTEGLVLITNNGPLGFAMLHPRYHVAKTYYVEVNDILGPDAPAFFESGVVFEDGTVCQS
                     AQLEVLSSASDKSCARVTISEGKFHQVKKMFLAYGVKVTYLKRISFGEFKLDEGMAVGS
                     YRTLTEAEKTILRTYLG"
     CDS             8285..9430
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244:amidohydrolase (Score: 359.1; E-value: 4e-109)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg210_11"
                     /transl_table=11
                     /translation="MTEVFYDHLAKTRHQIHQHPEVSGEEHETTVFLKAYLKNLGVEPL
                     NYPLKTGLIAEIGSGHPIIALRADIDALPIKEKTGLPYASDNGAMHACGHDFHQTSLLG
                     AAQLLKEREAELKGTVRLIFQLAEENFQGAYQVIEAGGIEGVSAIIGYHNNPHLKPGQI
                     GLRSGAILAGVEQFRVDVKGVSSHAARPDLGVDTVLVTTTIINNLQQIVARTVSPFESA
                     VLSVTHIEVGNTWNVLPAAGFFEGTIRTFEPKVREDVIARFEKVVQATADQFGAQVDIT
                     WGNSPYVTYNDQTLTPLIFENSKAFAEVIETLPSTGGEDFAAYQKEIPGVFAFVGTNGE
                     EDAPGWHHDDFLVKDEALPVAVNYYVENALFLLDYFKEQDD"
     CDS             9863..10000
                     /locus_tag="ctg210_12"
                     /transl_table=11
                     /translation="MLIGIPKEIKNNENRVALTPAGVQSLLAKGHVVLIETNASKFCYC
                     "
     CDS             9975..10313
                     /locus_tag="ctg210_13"
                     /transl_table=11
                     /translation="MRPSSVIVNVAVDQGGVVETVNRVTSHDKPVYETHGVLHYAVANI
                     PVAVARTSTIALTNVTIPYIEALAGVGFKQAIENDEGLRQGVTTYQVHITSQPVPEGLN
                     RSCTAIDE"
ORIGIN
        1 gtgtatataa atactgaacg tttatctttc tcaaaaaata caatatcgct cgaagggaca
       61 gaataattgt gtttaccaaa tgagaaggta aaaagtgctt ggcctatatc caaaaaacgc
      121 aaaatacgat ccaatacttt cattaacttt tgaggttcta tcggttttac gatatagtca
      181 aaagtctgaa cttcgaagac ttgttccata taatcacgat aacttgtcac aaaaataata
      241 ggaatgaaag gattaaattt tctaatcttt tgtgctacgt caattccatt gattcctggc
      301 atattgatat ccaaaaagac acagtggatg tctggcgtcc gctgatttaa gagtttttgt
      361 ggatttgtat aaagttttgt ttctagagga aatttatcat aagaaagtaa ataatgttct
      421 aattggctag catctctatc agagtcatca caaatagcaa cttttaacat tgaaaacctc
      481 ctcactcatt tctgtatgtt agttataacg ttaaaatggt caattatgac ataattgtaa
      541 gaaaaatgta agtttagtat acaatattct tattaaagat gaaaggagaa ttccaaatga
      601 aaaacattca agtacgtaag gccgtagctc aaaccgaaat tagctggggt attatttaat
      661 tgcttaaaaa tgttaaataa acatataagc aaatgttacc ttcgattcta tcacggaaaa
      721 tttttgatag aattactaca ataaggcgag gggaaattat agaatcacct catctttctt
      781 tttgaaaaac agtgaggaaa aaatgaaatc ccattgtcca agaataaaag aaatatatcc
      841 tatttataaa cttcacgata atttgtttag ggtaggctcc caaattggta taactactga
      901 aatcagtgat gaggacgata aaatgtggag tttagttaat attttagatg gaaggactat
      961 taatgacgtt gtagatatta tgttaactaa gtatccagat ttgacggaac aagatataat
     1021 aggtgctatt gaactattgg ataaggaggg ggttattgaa gaaggtgcta caataaattg
     1081 tattaaggaa agatatcatt caaatatcta ctattttagt cgctatttaa atagttttaa
     1141 agatagtata gatattcaaa agagacttaa tgaaacgaca gttcttttat taggacttgg
     1201 cggaggaggg tccaatatac taactttgct atctggtcta ggacctaaaa aaataaaaat
     1261 tgtggacttt gatatcattg aaaaaagtaa tctaggtagg caatttttat ataaggagga
     1321 agacgtaggg gctcttaaaa cacagattgc ccatcaagaa gtgtcaaaaa tgaattctga
     1381 tatcgaagtt gaaactcata atttacgtat aacatgtgta aacgacttgt tgccattatt
     1441 agacaatgtt gacattgtta tttgtgttat tgatgaacca caatatgata ttcagcgtat
     1501 tgtaaataaa gctgtagtta caaaaaatat tccgtgtgtt ttcggtgcaa gtcaagttag
     1561 tcgcagacgt gtttattctg tagtacccca tcaaacagga tgttttgatt gtttaaacat
     1621 tcattacacg aaaattgata gtctattctt ggaacaattt cggggtattc gtactgttac
     1681 taagaaaatt cctacaattg cttatggtcc ggctatgttt caattgacat ctgctattgt
     1741 tgatgaggct gttcgattaa taactaaata tgcagaacca atgagtctta atcgccaata
     1801 cgagattaat tatgaaaacg gagcgtcgtt cacacacaaa ccttggggac attatcctga
     1861 tgagtgtcct acatgtggta acggtaagga ggaaaattgg gaaatctttt ctcaatacgg
     1921 agaaataaaa ttatgacttt tgaaacgctc accattgaaa atttaacaaa atcatttgat
     1981 aaacaacatt ttgctaataa ccatatcttc ttagagctag aagctgcaaa aatcacagct
     2041 cttataggac ataatggtgc tggtaaatca actcttttaa agcaaatgat tggttttatt
     2101 aagcctgatc agggagatgt tcactacgga gatatttctt ttatacataa ccgtaaacaa
     2161 gctcgaacaa tgatgagtta tatgtcacaa cagtatgcac ctcttgaaaa gttaactgtt
     2221 gagcaaaatt tagagatgat tggaagaatg agagggttaa gtacctcaga actccaaaaa
     2281 gaaattgagc accttctagc agatctggaa atagtagaat accgtgataa aaaagggaag
     2341 aatctttcag gaggcttaaa acggcttaca tcttttgcca tggcattaat tggctctgct
     2401 gatatcatgc ttcttgacga accaaccaac gatgttgatc ctgtacgtcg tgaaaaacag
     2461 tggcgattat tacaaaaact ggcttataaa ggacacacta ttatcattgt tacccacaat
     2521 ctactagaag ttgaaaaata tgcggataat tttgctcttt ttaaccatgg taaattatta
     2581 aaatctggtc cagtacacca aatgtcttat aaaaatcatt atcaaatttc tttcaatttt
     2641 gttagtaaag aatttttaag tctattcgaa cattttacga tggtcaatgg ttgtgtttgt
     2701 cagatggaaa ttgaagaaag tgaattaacc cgaatactca ttcaagttaa ggaaggtata
     2761 gaaaaagggc ttatttcaaa cctttcagtt aagatgaaaa cattatctat ttccgatatt
     2821 tataaagagg agcttgttaa ctgatatgac tcaatttttt tacttacttc gttggaacta
     2881 tcttcgacaa aaaaatctat tcattctatt cacactagct caagtgcttt tgtccgtttc
     2941 acttcttttt gggtatccgt tggtaattgg taagatggac acaacaactg cttactatct
     3001 tgcctctgga tcagttttaa tgggagttat ttctattggc tgtacgattt catctcctgt
     3061 tatagccaat gccaagtcag aaggtcatgt ggactatatt cgagctttac ctattcctag
     3121 aattctaatt tctttagctg acctatgtat atggttaatt gctattttac caggtgtatt
     3181 cttcactttt ttattaggct gtcttcgctt ttctgtccaa ttaaatttgt caattttgtc
     3241 tgtttttgtg atgttactta tttgcctaac aatgattagt ctaggatttt caattgctta
     3301 tatattttcc caaaatattg tcacgctaat gtctcagctt attttaatga ttggtcttat
     3361 gttttcacca atcatgtatc cggcaggtcg tcttccagat tggttagatc aactttattt
     3421 tctacttcca tttgtccctt ctgcgaatct tcttagagct agcttttata gacatggaac
     3481 tgtttcgctt gtagatatag gagttcttat tttctggatt tttctgacac aactgcttat
     3541 cttagggaca ctacagaaag agttgtaata ctatcttatg gaaaacaatc ttacgaaact
     3601 caggtttaga catctggtac tcagcctttt tcttttgtga caattctcct ccaaacaaat
     3661 caattgccta gtcctctttg atagcggtat aatagttaag ttgattttat tatcaaacaa
     3721 caaatataga tatttcataa agaaagagga agtacaatgg caaaacctat tcgagtattg
     3781 ctttattata aatacgttcc catcgaaaac gctgagcaat ttgcggctga ccacttggct
     3841 ttttgtaagt caatcggtct aaaaggtcgt atcttggtcg ctgacgaggg gattaatgga
     3901 acggtttctg gagactatga aaccactcaa aaatacatgg actacgttca tagccttcca
     3961 gggatggagg acctttggtt caagattgat gaggaagaag aacaagcttt caagaagatg
     4021 tttgttcgct acaagaagga gattgttcac cttggcttag aggataataa ctttgatagc
     4081 gacatcaatc cacttgaaac tacaggtgct tacttgtcac ccaaagagtt taaagacgct
     4141 cttttggatg aggatactgt tgtccttgat acacgtaacg actatgaata tgaccttggt
     4201 cacttccgtg gtgccattcg tcctgacatt cgcaacttcc gtgaattgcc acaatgggtc
     4261 cgcgatcata aagaagagtt catggataag cgcgtggttg tttactgtac tggtggtgtc
     4321 cgctgtgaga aattctcagg ttggttggtc cgtgaaggct ataaagatgt tggccaattg
     4381 catggtggta tcgtgactta cggaaaagac ccagaggttc aaggggaact ttgggatggt
     4441 aagttgtatg tctttgacga gcgtattgcc gttgatgtca accgtgtaga tcctatcgtt
     4501 gtcggtaagg actggttcga tggcacacct tgtgaacgct atgtcaactg tggcaaccca
     4561 ttctgtaatc gccgtatcct tacttcagag gaaaatgaag acaaatacct ccgtggctgc
     4621 tcacacgaat gccgtgttca cccacgcaac cgttatgtct ctgaaaatga tttgagccaa
     4681 gaagaggttg ttgaacgcct tgcggcaatt ggtgagggct tggatgtaac accagcctaa
     4741 gtttaaatag agaagaagct gagagcaatc tcggtttttt attttgcaat ttatttctaa
     4801 aattacgaca catatatatt gcaattagaa atatatagtg tataattaag atgaaaacag
     4861 atggtgaacc taatcaatgt cgacgataat atcagataag atgaaaagga gggggcatgt
     4921 ggcaaagaat ttacgcttaa aagcagctcg agcagagcat gatatgaccc agggtgactt
     4981 ggcagaagcg gtaggtgcaa caagacaaac catagggttg attgaagctg gaaagtacaa
     5041 tcccagtcta gccctatgta ttgccatttg caaaacactg gacaggactt tggatcaact
     5101 gttttgggag atttaggaag gaagtaaaga tgatgaaatt taagcttgtt aataataaag
     5161 ttacagatga acgagaaaaa gctctaaata ataaagttgg tgcagaatgt ttttacataa
     5221 tgattgctgg gacgcttgcg tgcttggtct atagttcctt ctttaacaag ggggttatta
     5281 cctctaatta cttggccttt ccattattta tagcatggat ttggtctatt tatagatctg
     5341 aacgacttag tgttaacaca tttgggggtt ccggaatgac agtcttaggt tgtttactgg
     5401 tgactgcgct tatcactctt atgataatgt cagctaacta tcagtttaac cacaatgtct
     5461 atcataataa tcccctggat cctagatatc tcatggcttg gccacttact tatattttgt
     5521 atattccctt tgtctttttt atgaattggg ctctcacagc actgggaaga tatgagagaa
     5581 gacgtcttga aaaacagctg gacgatttgg agaatgaaga ataaatagtg atagaatcag
     5641 accgttcttt ttggtctgat ttttttgtgt tataatgggt cctaaaacta aggaggtcac
     5701 gtatgctact aactgaattt gatgcgaata gacaagcgat tataaatccc gaggccttac
     5761 atgagcctct tgaaggtttt cctaaaatag ctgtatcctg tttttctcgt ttgacctttc
     5821 aacgaatgct tgagatgttt ccccatgaac ttatctatga aatatccatg gcgaatgtgg
     5881 ctattccgat ttataagctt gttattgatg ataatgagtt ggccattttt aatgcacctg
     5941 taggcgcctc tgcctgtgtg ggtattttag aggatatttt tgccttggga gctgataaac
     6001 ttgtactttt tggtacttgt ggggtgcttg atgaagatat taaagagact tctattatta
     6061 ttcctagtca tgcccttaga gatgaaggga cgagttttca ctatgtggaa gccagcgatg
     6121 agattgcggt aaatgtgggt gttttagacc attttcgttc ctatctcaat gaacgtcaga
     6181 tttctcataa ggaaggcaag gtttggacaa ctgatggcat ttaccgtgag acgaatggta
     6241 aactcaaagc tagaaagtca gcaggagcca tttgtgtgga tatggagtgt tctgctgttg
     6301 cagctttagc aaagtttaga ggtgttgaca tctgccactt cttctatgct gcggaccacc
     6361 tttctgaagg taattgggac gcccgtaact tgatgaatca tatggacttg gatgaaaagg
     6421 ataagatagc tttattagct ttggagtttg cgtgtgactg gattaaacct taaaaattct
     6481 actttttaga tttattattt gtaatcaatc taaataacta ttataatact tttttataat
     6541 gattctaaat aaggagcgaa caattgttgg aagataagaa ttttgcagaa cgtttaaata
     6601 ttttgagagc tggtgtgttg ggtgccaatg atggcatcat ttccattgcg ggagtggtta
     6661 tcggtgtggc tagtgcgaca tctaatatct ggtttatctt gatttcagcc ttgtcagcga
     6721 tttttgccgg tgccttttcg atggcaggtg gtgaatatgt cagtgtgtca acgcaaaaag
     6781 ataccgaaga agcggctgtc gctaaggaac aagccctttt ggatcgctct cctgagtcag
     6841 ctagagaaag tttatatcaa accttcctca gtcaagggga ttgcgaaaca gaagcggaag
     6901 ttaaggtcaa tcaagccttc agtaaaaatc ctatcaaggt cttagttgag gaaaaatatg
     6961 gggtggatat ggaagaaatc accaatccat ggcatgctgc cgtatctagt tttctgtcct
     7021 tttcagtggg atctttgcct ccaacgctag ctatcctgct tttcccagat ccttatcgta
     7081 ttcctataac agcggttgtg gttgcactga ccttaatctt gactggctat gttagtgcta
     7141 aacttgggaa agcacctgtt aaacaagcga tgttgcgaaa cttggcagta ggactcttga
     7201 ccatgctcgt gacctatgta gttgggcaag tctttcatgt gaatgtgtaa ttgttagtag
     7261 tatgagtcta ccttttaggt aggctttttt tgtctactag accagactta tccatggtac
     7321 aatagggcta tgcgtttaga taaattatta ggacagtcgg gctatggttc tcgcaatcag
     7381 gtcaagaagc tcattcgtag tcgtcaggta tatgtagatg gtgtcctggc ggatcgagat
     7441 aatcttaatg tggatgctag tcttcaaacc atcatggttt ctggtaaaga actggagcat
     7501 gcgccagaag tctactacct tatgaataag ccgtcaggag tggtgtcagc cagaaaggac
     7561 aaggaacacc aaacagttat tgatttgatt aggcctgagg atcagcgaga gggcctttat
     7621 cctgtgggac gtttggatag agatacggaa ggtttggtgt tgattaccaa taatggtccc
     7681 ttgggctttg ccatgcttca cccacgctat catgtggcta agacatatta tgttgaggtt
     7741 aatgatattc tggggcctga tgcacctgca ttttttgagt ctggtgtggt ctttgaggat
     7801 gggactgttt gtcaatcagc tcagctggaa gttttaagtt ctgcaagtga taaaagttgc
     7861 gctcgagtca cgatttcaga aggtaagttt catcaagtaa aaaagatgtt tttggcttat
     7921 ggggtcaagg tgacctatct caagcgtatc tctttcggag agtttaaact tgatgaaggg
     7981 atggcagtag gttcctaccg aaccttgact gaagcggaaa aaacaatctt gcgtacttat
     8041 ttgggttagt agctaaggtg cgataggaac tttcaatcag ctgataagac tatcttatcg
     8101 ctagtcttaa tacgataaca cctataatga cagtattttt tagaggtata agaaatactt
     8161 atggaatact ataaatattt tttatttctc aagtatcgct tctggtggta tgatgaaatc
     8221 aattcgattg agagtttcac aaatagattg acaatccaaa actgatcaga gagggaggtt
     8281 cattatgaca gaagtatttt acgatcattt agcaaagacg cgtcatcaga ttcaccaaca
     8341 tccagaggtt tctggggagg agcatgagac gacagtcttt ttgaaagctt atttgaaaaa
     8401 tctaggtgtt gagcctttaa attatccctt gaagacagga ctcatcgctg agattgggtc
     8461 aggtcatcct attattgcct tgcgtgctga tattgatgcc ctaccgatta aggaaaagac
     8521 aggtcttcct tatgctagcg acaatggtgc catgcatgct tgtggtcatg attttcacca
     8581 gacctctctg cttggtgctg ctcagctttt aaaagaaaga gaagcagagc ttaaggggac
     8641 tgttcgatta atttttcaac tggctgagga aaatttccaa ggggcctatc aggtcattga
     8701 agcgggcggt attgagggtg tgtcagctat catcggttat cacaataatc ctcacttgaa
     8761 acctggtcag attggccttc gttcaggtgc tattttggca ggcgtggagc agtttagggt
     8821 tgatgtcaag ggtgtttcgt cccatgcagc ccgtcctgat ttgggtgtgg atacggtctt
     8881 ggttactacg actatcatta ataatttaca gcaaattgtg gctcggacgg tatctccctt
     8941 tgagtcagct gtattgtcag ttactcatat cgaagttgga aatacctgga atgttcttcc
     9001 agcagccggc ttcttcgaag gaacgattcg gactttcgag cctaaggttc gggaagatgt
     9061 cattgctcgc tttgaaaaag ttgttcaggc gacagcggat cagtttggtg ctcaagttga
     9121 cattacttgg ggtaattcac cttacgtgac ctacaatgac cagactctca cacccctcat
     9181 ctttgaaaat tctaaagcct tcgcagaagt gattgaaacg ctgccatcaa caggcggaga
     9241 agactttgcg gcttatcaaa aggaaatacc aggagtcttt gcctttgtcg gcactaatgg
     9301 tgaggaggat gccccaggct ggcatcatga tgatttcctt gtgaaagatg aagccttgcc
     9361 tgtagccgtt aattactatg tggaaaacgc tcttttcctc cttgattatt ttaaggagca
     9421 agacgactga ctatttcctt aattggaatc actagtaatg aaaaaactgt tgcggaaaga
     9481 agtccaatca tccagagttt ctcttgggtc ataagcaatt agcagaccaa ggactctttg
     9541 attattttat taagagtttt ccatgaagct taaggatttt aaattggtgc tgcttttgaa
     9601 aataaaaagg aggatgtgca taagaaaaaa tactcttttg atcatttagt ttacaactta
     9661 agagcccagc cgattggttg ggttcttttg tgaattgttt agatagttag gggagtatga
     9721 ttctaaggtc ttaaaatagc ggagattttt ttctcttgat tttagttaaa atgaaagcgc
     9781 tatcattaca gaaagataga taggaagtgg ttaagcgatt tgcacaatcc tttaccttat
     9841 gacctccgaa tgaggagaaa atatgttaat tggtattcca aaagaaatca aaaacaacga
     9901 aaaccgtgta gctcttacac ctgcaggtgt ccaaagtctt ttggctaagg gacacgtagt
     9961 attaatcgaa acaaatgcgt ccaagttctg ttattgttaa cgttgccgtt gaccaaggtg
    10021 gggttgttga gactgtgaat cgtgtgacaa gtcacgataa gcctgtttat gaaacacacg
    10081 gtgtccttca ctatgctgtt gctaatattc cagttgcagt agcacgtaca tcaaccattg
    10141 ctcttaccaa tgttaccatt ccttatatcg aagctcttgc aggagtaggc tttaaacagg
    10201 ctattgaaaa tgacgaaggc cttcgccaag gtgtaacgac ttatcaagtt cacattacta
    10261 gccaacctgt tccagaagga ttgaatagaa gctgtacagc tattgacgag tgactataag
    10321 tttataattc tatcagaatg aaagataagt cgcgccatga attggtgtgt tttagttagg
    10381 ataagaggta atcgtgtgtt tggtagttga tcgtcaagtg tctataaagc ttaaatctgc
    10441 ttattttttc taatctaggt attgttttat gctataatga gcagacatct caacattagt
    10501 aatgagcacc tatgactctt tctgttttta cttaaaaaat gcgctcataa agaggtttta
    10561 ccatagccaa tcatattcgt gttctcacag aaattatttt ctcttatctt gtcgtctttt
    10621 attttggtgt aaaaatcgat gtatcattga ccaagcttct aattacagta ggtgtggcag
    10681 cgctgcttga aatgctttac catgtgatac ttgctcgaag ataggagcaa atatttcttt
    10741 cgaagctttt tggagaaact gtggacaact ctttagaaaa aatgttgtgt tcttcttttt
    10801 tttttagttt tttaccacat aattttcaaa gggtgcatat atctccatta acataagata
    10861 tgaaatcggt tatatcaaaa actgtagcct ttttattttc cagttcatat atgtgcagtc
    10921 tgaaagatta aatgatataa tgccgatgaa taggaggata cagaaatgtt gaactatgat
    10981 ttgattgtta tcggtttcgg taaagccggt aaaacgttgg ctgctaagat gaatgcggct
    11041 ggtaagaaag ttgctgtcat cgagcgcagt aaagcgatgt atggtggtac ttgcattaat
    11101 attgcgtgta tcccaactaa gactatgatt gttgcggctg agaagggctg gtcatttgac
    11161 gacaccatga aagaacgtgg tgcagtgact agtcgtctta atgctaagaa ttataaaatg
    11221 ttggcagaca atggcgttga tgtcattgat gcagaagcac attttgtgtc aaataaggtc
    11281 attgaagtgg tggctggtga tgaccgtcaa gagcttacag ctgagactat tgttatcaat
    11341 acaggcgctg tgtctaatat cttgcctatt cctggcttga caacaactaa gcatgtttac
    11401 gactcaactg gcattcaaac tcttgaagct ttgccaaaac gcttgggtat cctaggtggt
    11461 ggtaatatcg gtcttgaatt tgctggcctt tataaccgtt tgggtagtca agtgactgtc
    11521 ttggatgcag cgactagctt cttgccacgt gtagagccat ctattgctaa gttggccaag
    11581 caatacatgg aagaggacgg cattgtcttt gagcaaggtg ttagaacatc tgaagttaag
    11641 aatgacggtg atgaagttgt cgttgttact gacaaagggg acttccgttt tgatgcgctc
    11701 ctctatgcga caggacgcaa gcctaatatt gaaccccttc acttggaaaa tactgatatt
    11761 gccttgactg aacgtggtgg tatccaggtt aataagcatt tggaaacaag tgttccaggt
    11821 gtctttgcgg tgggtgatgt taatggtgga cttcaattca cttatatctc actagatgat
    11881 ttccgcattg tctttaatta cctaactggt gatggtagct ataaccttga aacacg
//
