LOCUS       gnlProkkaPFGKIKKO_43   13946 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PFGKIKKO_43.
ACCESSION   gnlProkkaPFGKIKKO_43
VERSION     gnlProkkaPFGKIKKO_43
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 16:21:04
            Original ID  :: gnl|Prokka|PFGKIKKO_43
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13946
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..2685
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     674.1; E-value: 4.8e-204)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.4e-79, bitscore:
                     256.4, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 9.2e-09,
                     bitscore: 26.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.6e-19, bitscore:
                     60.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFSSIGVGSFSDISYPQKIGENYKKKVSVSGEWLSSICMMLENE
                     DSVLLKLHIQWNQKVLELSDKYQLSNVNYWGISEISKDLFVKKTGLLEFIQKLTYRSEV
                     SVLELVHTIQSKSPDLEKQKILDYIRNLITNEFLFTNLRKVAMSHKDLDDLINILKDID
                     EQRKLTEDLLQIKNCIEQYAKLELGEGISQYTEICKKMSYIFNDKKQHYLKVDLVNCCD
                     SVLPKNLKKKMEDFVNFISKINLAKGYRNRELESFTEKFVEKYGEYVEVPIKELLDGNL
                     GLGLPKQTLGTHVKSSSSVEEQNFLSYLSKEVFKAVKNCKKEIDISNIPLGLLYPNSDR
                     FVANQLELYCEIKNFESQPVISVVPNTGSDMIGKSIGRFASYFPNSYISLDSQLDNVEL
                     IEFPRDSKNLNVMSAQNAHSKKLLLSYDDNDNTSIELDSVVVGVIKTEYRYKLYFRDLR
                     TGSIVNFVTTSMLNHKSNGVFSDLARFLLAVSLEWQDNPFSVFRIIENFDYLPYIPKIK
                     YGNIILSEEKWVLSDIDKNDLSSIKQWKKDFDVPRLLYFHKDDERLLVDLENDLDTQWL
                     LKQNVDKLYFTRFEKYDGKNCEFIFGFENYQSSINHYSMQEKSVRRLTNNFYKNYVKTF
                     SSDWIYFRLYGINSSILLELRERLLLFTDELLVEKLISDFHFVNYSDKDNGSLRLRFKI
                     NNDDNFEDLRFRIAHWIDFLLESGFCNDVSFNLYEREIERYGGDNFITVCERMFSIDSF
                     LTLKLFSKKLLNDKDLFSVLHSTFLYIRLLGLTLGQLLELLKRNLTQNRYRKSFKKLFP
                     NNTIIVKEFKEYFDCKNQFEIFNEVFREFPPIDGHFEDKNDIVHSLLHMHMNRVGIFPY
                     REKEYLYFIMYIAEVLDNYEEYT"
     protocluster    1..13946
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[0:3946]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..3946
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..13946
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13946
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             2669..3508
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     173.6; E-value: 1e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_2"
                     /sec_met_domain="LANC_like (E-value: 1.7e-26, bitscore:
                     83.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNILEKYEEIICKVDKLVLDSDIIDRLQGSYYTENRSYLSEYPS
                     IIIYLSYRLINCDNKEYSKLLYNRVNYYLQELLNSIKLNSTNNISLCYGFMGYVYTLEF
                     LSKNCKEYDKLLDTLETILLALTKDRLREIKSSNIVKEEYFDIIQGVSSVARYLLSKEE
                     STSEQELLVKEILNYLADLIINEPTIYVEYMPNEKLRKRFPSGYINLGVAHGILGPLYV
                     LALGFEKFNITKHLLSIEKGLSYYENAFFTNTIGKIIGWNGRVSDNVDNEEFRFNIS"
     CDS             3527..3946
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     92.9; E-value: 3.3e-28)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_3"
                     /sec_met_domain="LANC_like (E-value: 8.6e-17, bitscore:
                     51.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARVLYNIAKIIDSQKLREMATNVFTSSIDYLNSSEILNNAICHG
                     RSGIMLLFNLMYLDTGKIQFKVISDHLFKEIVNEASNSEYIFVERDIYFRGVNFDEVID
                     YIDFGLLNGVSGIVLALMAQRTGNAYPLDRMLFMQ"
     CDS             3976..5241
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 94.5; E-value: 1.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg36_4"
                     /transl_table=11
                     /translation="MRKIFKNKLYLKVLISDLISNFGDTLYFIALMTYVTEIKESNLAI
                     SIVNISETLPILFTIFFGIIADRTLNKVEMIIKTLWLRVLLYLLVAVAMNFKPSIIVVI
                     IASLVNLVADTLGQFENGLFYPISNRIVKKSDREETMAFRQTVVSTMNIVNQSLGAFLI
                     TFFSFSHLAFINSLTFAISLLIMLAIRNQINSYYDETISTSKISQFDFKASFSEIISNL
                     KLSINHLFSIGNMKEALLVIPILNGSLAILTPLVVVDLSKDSNLTIINSAITISLLGIS
                     TVSGGILGGTLILISKKFKSLSIGTLLKMNLTTVLLSFVAFYFQNIYLIILSSFLSSVL
                     VSALNPKMGTIIFNNIDETKLATIFGGMVTYFQIGDIVSRLLFSTLVIYLPYGYIALIY
                     IAVVFVAILYTLKSSNHIEREF"
     CDS             5470..5982
                     /locus_tag="ctg36_5"
                     /transl_table=11
                     /translation="MMFDDRLEIHSPGKLPNIVTVENIKHERFSRNPRIARTLTEFGWV
                     REMNEGVKRIYSEMESYFLHEPKYTEPGNKVVLTLENNILSRHLRVNDKMMKKYDEFND
                     LNDDEKAILHIMYNTGEKMTTALAARITNRGRNFASKLLKSLVKKEILEWHGTSKQDRN
                     QYYTLAE"
     CDS             complement(6369..7523)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 99.1; E-value: 7e-30)"
                     /gene_kind="other"
                     /locus_tag="ctg36_6"
                     /transl_table=11
                     /translation="MSIKKTKNGTYQLRLYIPEDVQAKLGLGKLFERKYKTRREAKEVE
                     LKLSIDIKNAKSGKSHINIKNKGEIIFKKFYEDIWLEPYKEDQTTTTIKPPTKATVFQT
                     ENIFRLHILPILGKYSIEYPNNNKQLILSLLTPKANSYANFKVIRSYVNSVFDWAEELE
                     YIPSNKLRKTITRIKANKKILLKESKREEDLSLDKEELKLWLQAFDIDLEKGLIDLKDY
                     TLFYTTFFLSDRKSESYALQWKHINFSTGETLIEQALDRFGNIKPTKGRKKTLFKTPIE
                     LIELLANWKERQQEELKLFGLRQTQKQFVFTYNDRSHNINLPLHVDYLNYRMKSVRRRH
                     LELAPASPHKLRHAGVTLAKQAGYSLEAISEALTHSDKQLQRLM"
     CDS             complement(7534..7806)
                     /locus_tag="ctg36_7"
                     /transl_table=11
                     /translation="MLVQLPEEQTQEIQQMIATLIKSEIHHFKEDIGADSTFLNKKQTY
                     NYLGISNNTLDIGIAMGLPYIRIGKSIRFNKKSINQWMTRLEISA"
     CDS             complement(7868..9121)
                     /locus_tag="ctg36_8"
                     /transl_table=11
                     /translation="MFINETNIKSLDICEISSPFEQALPNIIDESFPFDISNLFDTKGN
                     ALFNFSNQYLNPNTKILDSNNATLYEVDFDSLSPDTKAKLQEGAYKIGESRKVEGNLRA
                     VIVDTTDQKNRVEDLTLRKMTNNNENQVPSDLIAQAQLKQIYNLLLDIKENQEYQIRWD
                     RNNSIIRPFFSARTKVIEANNSKDFREKVKLLKKANTLFEESVSAIKSDIISNRDEIIK
                     KISQPTYCQASLQTHADFLLQDIEIMTKIVGMQIYIDLLNNEEMLLSFQGSMELVSKQN
                     IPYKTNYLKELAKKLPYVKESKWIKNNSIPKVSLLELIHNHYSYSKNNRDLFINVNTKL
                     IEFNQTSDTNLSNAETAKIETEKKMTLKTKKCKTCKKTISSPKTIPICDACRNKGKQLT
                     GVGVALLVFFNKIINKKN"
     CDS             complement(9290..9889)
                     /locus_tag="ctg36_9"
                     /transl_table=11
                     /translation="MTKRKNLRVVLSTRQQMVASTSPIPLALGKGVLKPCKNSIPISMS
                     MEVHQKPLNRRQEKPETEAVSQQGMSPQGYSLTKEINTSSHTGLSYPWGQCTWFVYNRG
                     KEVGVSFGKYMVNGGQWMNAPGYQTTHIPTEHSALSFSPGQAGADSTYGHIAFVEQVKS
                     DGSILISESNIKGLGVVSYRTFDAETAKQFTYVIGH"
     CDS             complement(10056..10742)
                     /locus_tag="ctg36_10"
                     /transl_table=11
                     /translation="MTINHFKGKQFQQDVIIVTVGYYLRYNLSYREVQEILYDRGINVS
                     HTTIYRWMQEYGKLLYQIWKKKNKKSFYSWKMDEIYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQTAYAFLERLVKQFDEPKVVVTDKAPSITSAFKKLREYGFYQGTEHCTIKY
                     LNNLIEQDHRPVKRHNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKV
                     LLGIPA"
     CDS             10892..12109
                     /locus_tag="ctg36_11"
                     /transl_table=11
                     /translation="MEQSQAKKHDNTMTNKILMRLIALVLGLLFLEILIIHSKNEQQKS
                     VSNQVQTARIMANGDLLYHDGLYMSALQADGSYDFTENFTYVKPWLKQADLVLGDFEGT
                     INPDYPLSGYPLFNAPQSVTAVISDAGYDVMDLAHNHILDSGLEGAFTTADAFKEVGID
                     PVGVYENPVRDKAPLFIKNVNGIKVAILSYAYGFNGLESNLTEKEIANHLSNLDEKRMK
                     VEIERAEKEADVTVIMPQMGVEYRLEPTDEQVKLYHKMIDWGADIIFGGHPHVVEPSEV
                     VKKDGQQKLIIYSMGNFISNQRIETMDGVDNAAWTERGVLMDVTLEKKNCQTTIKTAQA
                     HPTWVNRTPKGTISPEGYPLYTYQTYILEDLIKGGKYRNKLDEETKERIDTAYKEMNAH
                     VNLKWK"
     CDS             12430..12696
                     /locus_tag="ctg36_12"
                     /transl_table=11
                     /translation="MKAIITVVGKDKAGIVAGVATKIAELGLNIDDITQTILDEFFTMM
                     AVVSSEDKKDFTHLRAELEAFGESLNVKINIQSSAIFDAMHNL"
ORIGIN
        1 ggattattta gttcaattgg tgtagggtct ttttctgata tctcatatcc ccaaaagatt
       61 ggagaaaatt ataagaaaaa agtatcggtg agtggagagt ggttaagttc gatttgtatg
      121 atgttagaaa atgaggattc tgtcttatta aaactacata tacagtggaa ccaaaaagta
      181 cttgaattat cagataagta tcaattaagt aatgtcaatt actggggaat ctctgagata
      241 agtaaggatt tatttgtcaa gaaaactgga cttttagaat tcatacaaaa attaacgtat
      301 agatcggaag tcagtgtgtt agaactggta cacacaattc aaagtaaatc tcctgattta
      361 gaaaagcaga aaattttaga ttatatacgt aatttgatta ctaatgaatt tttgtttaca
      421 aacttgcgaa aagttgcaat gagtcataaa gatttagatg atttaattaa tattttaaag
      481 gatattgatg agcaaagaaa attaactgag gatttattgc aaataaaaaa ttgtattgag
      541 cagtatgcaa aattagagtt gggagaaggt atatcccaat atactgaaat ttgtaaaaaa
      601 atgtcgtata tttttaatga taaaaaacag cattacctga aggtggattt agtaaattgt
      661 tgtgattcgg tgctgcccaa aaatttaaaa aagaaaatgg aggattttgt taattttatt
      721 tcaaaaatta atctggctaa aggttatcga aacagagaat tagaatcatt tacagaaaaa
      781 tttgttgaaa aatatggaga atacgtcgaa gttccaatta aagaattatt agatggtaat
      841 ttaggactgg gtttaccaaa acaaactttg ggaactcatg taaagtcatc aagtagtgta
      901 gaagagcaaa attttttgtc ttatctgagt aaagaagtct tcaaagctgt taaaaattgt
      961 aaaaaagaga tagatatatc aaatatacct ttaggattgt tatacccaaa ttcggataga
     1021 tttgttgcaa atcagttaga gttatattgt gaaattaaga attttgaatc tcaacctgtt
     1081 atatcagttg tcccaaatac agggagtgac atgataggga agtctattgg aaggtttgcc
     1141 tcctattttc ctaattctta tatctcgtta gattcacagt tggataatgt agaattaata
     1201 gaatttccaa gagatagtaa gaatttaaat gttatgtcgg cacagaatgc tcattctaaa
     1261 aagttattat tatcttatga tgacaatgat aacacatcga ttgaattaga ttctgtggtg
     1321 gtgggggtta taaaaacaga atatcgatat aaattatatt ttagggattt acgaaccggc
     1381 tcaattgtta attttgtaac aacatcaatg ctaaatcata aatcaaatgg agtatttagc
     1441 gatttagcaa gatttttgct agcggtttct ttagaatggc aagataatcc gttttcagtg
     1501 tttaggataa ttgaaaattt tgattatctt ccctatattc ccaaaattaa atatggaaat
     1561 ataattttaa gtgaagagaa gtgggttttg tcagatatag ataaaaatga tttatcttct
     1621 attaaacagt ggaaaaaaga ttttgatgta cctagactac tgtattttca taaagatgat
     1681 gagcgtctat tggtcgattt agagaatgat ttagatacac agtggctttt aaaacaaaat
     1741 gtggataaac tgtattttac acgttttgaa aaatatgatg gtaaaaattg tgagtttatc
     1801 tttggatttg aaaattatca aagtagtata aatcattatt ctatgcagga aaaatctgtt
     1861 agaagattga caaataactt ttataagaac tatgttaaaa cattttcgag tgattggatc
     1921 tattttagat tatatggaat taattcatca attctacttg aactaagaga gcggcttctt
     1981 ttgtttacag acgagctatt ggttgaaaag ctaattagtg attttcattt tgtaaattat
     2041 agcgataagg ataatggatc gcttcgatta cgatttaaaa taaataacga tgataatttt
     2101 gaagatttaa gatttcgaat tgcacattgg atagacttcc tactagaaag tggtttttgt
     2161 aatgatgtta gttttaattt atacgagagg gaaattgaga gatatggtgg agataacttt
     2221 ataacagttt gtgagaggat gttttctatt gacagttttc ttaccctaaa gttattttcg
     2281 aagaaattat taaatgataa agatttattt tctgttttgc attcgacatt tttatatatt
     2341 cgattattag ggctcacatt agggcaatta cttgagttac tgaagaggaa tttgactcaa
     2401 aatagatatc gtaaaagttt taaaaagtta ttcccgaata acacgataat agtaaaggaa
     2461 ttcaaagaat attttgattg caaaaatcag tttgaaattt ttaatgaagt ttttagagaa
     2521 tttccaccta ttgatggaca ttttgaagat aaaaatgata tagttcatag tttacttcat
     2581 atgcatatga acagagtagg catatttcca tatagagaaa aagaatatct ttattttatc
     2641 atgtatattg cagaggtgtt ggataattat gaggaatata cttgaaaagt atgaagaaat
     2701 tatctgtaaa gtagataaac tcgtgttgga tagtgatatt attgacagat tgcagggatc
     2761 atattataca gaaaatagaa gttacttatc ggaataccca agtataatta tatatttatc
     2821 gtataggttg ataaattgtg ataataagga gtattctaag cttctctata acagagtaaa
     2881 ttattatcta caagaattgc taaattctat taaattgaat agtactaata atatttcact
     2941 ttgctatgga tttatgggct atgtatatac cttggaattt ttatctaaaa attgtaaaga
     3001 atatgacaaa ttactagata cacttgagac aattttatta gctttaacaa aagataggct
     3061 acgtgaaata aaaagctcta atattgttaa agaagaatac tttgatataa ttcaaggagt
     3121 atctagtgta gctagatatt tgcttagcaa agaggaatcg acttctgaac aagagttatt
     3181 agtaaaagaa atattaaatt acttagcaga cctaataatt aacgagccaa ctatttatgt
     3241 ggaatatatg ccaaatgaaa aattaaggaa aagatttcct agtggctata ttaatctagg
     3301 tgtagctcac ggtatattgg gaccactata cgtgttggcg ttaggatttg aaaaatttaa
     3361 tataacaaaa cacctacttt caatagaaaa gggcttgagt tactatgaga acgccttttt
     3421 taccaataca attggaaaaa ttattggttg gaatggtaga gtcagtgata atgtggataa
     3481 tgaggaattt agatttaata taagttagtg ctatggcagt cttggaatgg caagagtact
     3541 atataatata gcgaaaatca ttgatagtca gaaattacga gaaatggcga cgaatgtatt
     3601 tacttcatct attgattacc ttaatagcag tgagatttta aataatgcaa tttgccatgg
     3661 tcggtctgga ataatgcttt tgttcaattt gatgtattta gatacaggaa agatacaatt
     3721 taaggttatt tctgatcatt tgtttaaaga aattgtaaat gaggcttcta attctgagta
     3781 tatatttgtg gagcgtgaca tatattttag aggcgtaaac tttgatgaag tcattgatta
     3841 tattgacttt ggattgctaa atggtgtttc agggatagtt ctagctctaa tggcacaaag
     3901 gactggaaat gcctacccat tggatagaat gctgtttatg cagtgaagtt tgaaagtata
     3961 taataaagga gacatatgag aaaaatcttt aaaaataaac tatatctaaa agttctgatt
     4021 tcagatttga tatcaaattt tggagataca ttatatttta tagctctcat gacctatgtt
     4081 acggagatta aggagagtaa tttagctatt tcaatcgtaa atatatcgga aactctacct
     4141 attttattta caatattttt tggtatcatt gcagatagaa cgctgaataa agtggaaatg
     4201 attattaaaa cgttatggct acgggtgctg ctatatttat tggttgctgt ggctatgaat
     4261 tttaaacctt ctattatagt agtcataatt gctagtctcg ttaatcttgt tgcagataca
     4321 ttgggacaat ttgaaaatgg tcttttttat ccaatttcta atcgaatagt gaaaaagtca
     4381 gatagagaag aaactatggc gtttaggcag actgttgttt ctacgatgaa tattgtaaat
     4441 caatcattgg gggcgttttt aattactttt tttagttttt ctcacttagc ttttataaat
     4501 tctctaactt ttgctattag tctgttaatt atgttagcaa tcagaaatca aattaatagc
     4561 tattatgacg agacgatttc gactagtaag atatctcaat ttgactttaa agcttcattt
     4621 tctgagatta tttcaaattt aaagctctcg attaaccatc tatttagtat cggaaacatg
     4681 aaggaagctt tacttgttat accaattctt aatgggagtt tggcaattct cacgccatta
     4741 gttgttgttg atctttctaa agattctaat ttgacaatta ttaattcagc gattacgatc
     4801 tcgcttttag gaattagcac tgtttcagga ggaatacttg ggggcacttt aattctaatt
     4861 agtaaaaaat ttaaaagcct ttccataggc actttgctaa aaatgaattt aacgactgtt
     4921 ttactatcat tcgttgcttt ttacttccaa aatatttatt taattatatt atcatcattt
     4981 ctttcgagtg tattagttag tgcattaaat cctaaaatgg ggactatcat atttaataat
     5041 attgatgaga cgaagttggc tacaatattt ggaggaatgg tgacatattt ccaaatagga
     5101 gatattgtgt caaggttatt gttttctacc ttagtgattt acttaccgta tggttatatc
     5161 gcattaatat atatagcagt tgtttttgtg gcaattttat atacattaaa aagttcaaat
     5221 cacatagaaa gggaatttta aattagttaa atgattatag ttttccaaat tttctactat
     5281 tgaaaaccta ttttcaagat tgagtactaa agttcgagat tttgttcgta ctcagcttag
     5341 agaatttcaa tatttggatg atgggcaatt taaaacatta ccagagtatc cagaatttgc
     5401 ttggtttgaa gggatgtaaa tgcggtaact catagaaatt gctccatttt tggcgattat
     5461 atccgaatta tgatgtttga tgatcgatta gaaattcata gtccaggtaa gcttcctaat
     5521 atcgtaacgg ttgaaaatat taagcacgaa cgtttttctc gtaatcctcg tattgctaga
     5581 actttaacag aatttggatg ggtacgagaa atgaatgagg gagtgaagcg aatctattct
     5641 gagatggaat cttatttctt gcatgaacct aaatacacag agccaggaaa taaagttgtt
     5701 ttaactcttg aaaataatat tttgagccga catttgagag ttaatgataa gatgatgaaa
     5761 aaatatgacg aattcaatga tttaaatgat gatgagaaag caattttaca tatcatgtat
     5821 aataccggag aaaaaatgac tactgctttg gccgctagaa taacaaatag gggtagaaat
     5881 tttgcaagta aattattaaa gagtcttgta aagaaagaga tcctggaatg gcatggcaca
     5941 agtaagcaag atagaaatca gtactatact ttggcagaat agcggatcta tttataactg
     6001 gagtgcagaa gagtgcagta gttcggagta aaacgcagta agtgaatttc ccctgttttc
     6061 ctcaaaaaat ctcaaatttt ttgaaattct ggacaaaaga aaaggactag ttgcctgtag
     6121 tttctaccta ttaagttata ttgaaattca ttggtttaaa accaggtctt aagaaagctc
     6181 gtaaagcttc acaattctca aaacgttaat caatacgatt atatcaatgt ttcaagacat
     6241 tcaagagtta tctcttgggt gtcttttttt attcaaaatt cgatagtttc caccaatttt
     6301 ccaccattac tttttcaagc tacgaaatgc aatatcgcct actgtccgat taactatatc
     6361 ttttgtattt acataagtct ttgtaattgc ttatcactat gagttagagc ttctgaaata
     6421 gcttcaagag aataacctgc ttgtttggca agagtaacac ctgcatgtct tagtttgtgt
     6481 ggtgatgctg gtgcaagttc tagatgtctc cgtctgactg acttcattct ataatttaga
     6541 taatccacgt gaagaggtaa attaatgttg tgtgaacgat cattataggt gaatacaaac
     6601 tgcttttgag tttgacgcaa tccaaataat tttaactcct cttgttgtct ttctttccaa
     6661 ttagctaata gctcaattaa ttcaataggt gttttaaaaa gagtcttctt acgacctttg
     6721 gtgggtttta tatttccgaa acgatctaaa gcttgttcta tcagtgtttc tccagtagag
     6781 aaattgatgt gtttccattg aagagcataa ctttctgatt ttctatcgga taaaaagaat
     6841 gtcgtataaa agagagtgta gtcttttaaa tcaataagtc ctttctctaa gtctatgtca
     6901 aaagcttgta accataattt cagctcttct ttatcgagag ataaatcttc ctctcgtttg
     6961 ctttctttaa ggagaatctt tttattagct ttaattctag taattgtttt gcggagttta
     7021 tttgatggaa tatattctag ttcctcagcc caatcgaaaa cagaattaac atagctccta
     7081 attactttga aattagcata gctatttgct ttgggagtaa gtaatgaaag aataagttgt
     7141 ttattattat ttgggtattc gatagaatat ttacccagaa tgggtaaaat gtgtagcctg
     7201 aatatatttt ctgtttggaa aactgttgct tttgtgggtg gttttattgt tgttgtggtt
     7261 tgatcttctt tgtatggttc gagccaaata tcttcataaa attttttgaa tatgatttct
     7321 cctttatttt ttatgtttat atggcttttt ccagacttag catttttaat gtcgatagaa
     7381 agttttaatt ctacttcttt ggcttctcgt ctggttttat attttctttc aaaaagttta
     7441 cctaaaccca attttgcttg aacatcttct ggaatgtaaa gtcgtaattg atatgttcca
     7501 ttttttgttt tcttaataga catatttacc tccttatgcg ctgatttcta atcttgtcat
     7561 ccattgattg atacttttct tgttgaaacg aatagatttt ccgattcgga tatagggtaa
     7621 tcccattgca atcccaatat caagtgtatt attagagata cctaggtagt tgtaagtctg
     7681 ttttttgttt agaaaagtgc tgtcagcccc aatatcctct ttaaaatgat gaatttcact
     7741 ctttattagt gttgcaatca tttgctgaat ttcttgagtt tgttcttctg gcaattgtac
     7801 tagcatatat tattctcctc ttaaaaataa aaaagaagag taaaatactc tcctgctgtt
     7861 aaaaagatta attcttctta tttattattt tgttgaaaaa aactagcaaa gcgaccccga
     7921 cccctgtcaa ttgtttgccc ttattacgac atgcatcaca aattggtatt gttttaggtg
     7981 atgagattgt ttttttacaa gttttacact tcttcgtttt tagtgtcatt tttttctccg
     8041 tttcgatttt tgctgtttca gcattactta aattagtgtc actagtttgg ttgaattcaa
     8101 ttaatttagt atttacatta ataaataagt ccctattgtt ttttgagtag ctgtaatgat
     8161 tatgaattaa ttctaacaaa cttacttttg ggatactatt attctttatc cattttgatt
     8221 cttttacata aggaagtttt tttgctagtt ctttcaaata atttgttttg tatggaatat
     8281 tttgtttaga aactaattcc atcgaacctt gaaaagatag tagcatctcc tcattattta
     8341 ataaatctat ataaatttgc ataccaacaa ttttagtcat aatttctatg tcttgaagta
     8401 aaaaatcagc atgtgtttgt aaagaggctt gacagtatgt tggttggctg attttcttaa
     8461 taatttcatc tctatttgaa attatatcgg atttaatagc acttactgat tcttcaaata
     8521 atgtatttgc cttctttagt aacttaactt tttctctgaa atctttgcta ttgttggctt
     8581 ctataacttt tgttcgagct gaaaaaaatg gacgtattat actattgttt cgatcccatc
     8641 taatctgata ctcttgattt tctttgatat ctaacagtaa gttatagatt tgtttaagtt
     8701 gagcttgagc gattagatca ctaggaactt gattttcgtt gttattggtc attttcctta
     8761 atgtcaaatc ttcaacacga ttcttctgat cagttgtgtc tacaattaca gctctaagat
     8821 ttccttctac ttttctagat tccccaattt tataagcgcc ctcttgaagt ttcgctttgg
     8881 tgtcaggaga tagactgtca aagtcaacct catatagagt agcattattg gagtctagta
     8941 ttttagtgtt aggattaaga tattggtttg aaaagttgaa taaggcgttt cccttagtat
     9001 caaataagtt tgagatatca aaggggaaac tttcatcaat tatgttgggg agagcttgtt
     9061 caaaaggact acttatttca cagatatcaa gtgatttgat atttgtctca tttataaaca
     9121 actcaaaaga ttgtaaattt ttttgattaa ttcttctttt tgtttttctg atttagcaac
     9181 ttcgttcatt ggttcacctg gtcacttttg tattaattat aacatttagt attgatttta
     9241 gacgaatcta tatcaaaaat attgaaaatt aatattatta aagctaacat tagtgtccaa
     9301 taacataagt aaattgtttt gctgtttctg catcaaaagt gcggtagcta acgactccta
     9361 gtcctttgat gtttgattca gagatgagga tggagccatc tgatttgact tgttccacaa
     9421 aggcgatgtg gccataagtt gaatctgctc cagcttgccc tgggctaaaa gatagagcgg
     9481 agtgttcggt tgggatatga gttgtctgat accctggggc attcatccat tggccaccat
     9541 ttaccatata ctttccgaag ctaacaccga cttcttttcc tcggttatag acaaaccagg
     9601 tacattgtcc ccaaggataa gacagtcctg tgtggcttga ggtattgatt tctttggtga
     9661 ggctatagcc ttgtggggac atcccctgtt gtgacaccgc ctccgtctct ggtttttcct
     9721 gtcgtctgtt caggggcttt tggtgtacct ccatgctcat cgatataggt atcgagtttt
     9781 tgcatggttt cagcacgccc tttcctagag ccagaggtat cggtgaagta gacgccacca
     9841 tctgttgacg tgttgagaga accactcgca aatttttgcg ctttgtcatc ttggactttg
     9901 aaggttttat ttttattgcc aatgatggtc tgctttgtga gtccaacaac ggctatttca
     9961 tcgttaaaat tattggcatt ttctggatta gagtcaaatg cggttctgtt gcaaagtttt
    10021 aaataaagaa taaaatccct tacggtatct atgatttaag ctgggattcc caataatacc
    10081 ttgatttcag tacagaccga aaacccgaag agagtgcctt cttttcgggt tttcttatat
    10141 aatcctcgga tggcttccat gcctttaatc gtggtagagg cagtgcgtaa acttcgatag
    10201 aatttattgt gtctctttac tggacgatgg tcttgttcaa tcaaattatt caggtattta
    10261 atggtacagt gttctgtccc ttgataaaag ccgtattctc ttagtttctt aaaggcactt
    10321 gtaatagagg gggctttatc tgtgactaca accttcggtt catcaaactg cttaactaac
    10381 cgctcaagaa aagcataggc tgtttgtgtg tcccgttttt tacgtaacca aatatccaag
    10441 gttaaaccat ctgcatcgat ggctcgatac aaataatgcc attttccttt aattttgatg
    10501 tatatttcat ccattttcca tgaataaaag gattttttat ttttcttttt ccaaatttga
    10561 tagagtagtt tgccatattc ttgcatccaa cgataaatcg tcgtatgaga aacgttaatg
    10621 ccacgatcat ataagatttc ttgaacttca cgatagctaa ggttataacg aagatagtag
    10681 cccacggtta caataatcac atcctgctga aattgctttc ctttaaaatg atttatcgtc
    10741 attcctcctg ctatcttttt ctattattct accttatttg atagtagatt taaaactttg
    10801 caacagaacc gatgtaaccg tttattaatc ttttttatca tctatggata acattttttt
    10861 gttacactag gagtatgaaa aaggagatat gatggaacag agccaagcta aaaagcatga
    10921 taatacgatg actaataaga ttttgatgag gttgattgct cttgtcttag gtttgctttt
    10981 tcttgaaatt ttgattattc atagtaaaaa tgagcagcaa aagagtgttt caaatcaagt
    11041 acagacagca cgtatcatgg ctaatgggga cttgctttat catgacggtc tctatatgag
    11101 tgccttgcag gcagatggta gttatgattt tactgaaaat tttacatatg tgaagccatg
    11161 gttaaagcag gctgatttgg tcttgggtga ttttgaggga actatcaatc ctgattatcc
    11221 tttgtcaggc taccctctgt ttaatgctcc tcaatcagtg acggcagtta ttagtgatgc
    11281 cggctatgat gttatggatt tggcccataa tcatattttg gactctggtt tagagggagc
    11341 ttttacaaca gccgatgcat ttaaagaggt gggcattgac cctgttggtg tttatgaaaa
    11401 tcctgtgcgt gataaggcgc ctctgtttat caagaatgtt aatggcatca aggtggcaat
    11461 actttcttat gcctatggtt tcaatggctt ggagtcaaat ctgaccgaaa aagagattgc
    11521 gaatcatttg tcgaatcttg atgaaaaacg gatgaaagta gagattgagc gtgctgaaaa
    11581 agaggctgac gttacggtta ttatgccaca gatgggcgtg gaatatcgtt tggaaccgac
    11641 agatgaacag gtaaagcttt accataagat gattgattgg ggtgctgata ttatctttgg
    11701 gggccaccct catgtggttg agccgtctga agtggttaaa aaggatggac agcaaaaact
    11761 cattatttac tcaatgggga attttatctc taaccagcgc atagagacta tggatggtgt
    11821 ggataatgca gcatggacag agaggggcgt cttaatggat gtcactcttg agaaaaagaa
    11881 ttgtcaaacc acgattaaga cagctcaagc gcatccaacc tgggttaacc gcacacctaa
    11941 gggaacaatt tcgccagagg gatatccttt atatacttat caaacctata ttttagagga
    12001 tctcattaaa ggtggaaaat acagaaataa actagatgaa gaaactaaag agcgtataga
    12061 tactgcctat aaagaaatga atgctcatgt taatctaaaa tggaaataaa gctaagatat
    12121 cgctaaaatt tggcgatatt tttctttatc gacaagttac caacagactt atccacaggt
    12181 gttgataagt ctgttctcag tgttaaacct tgatttttca aggttttatt agaattgtat
    12241 tgttttactt gttaataagt ttatccacaa gttgttggat tgatagagac tgaattttat
    12301 aaacgatact ggttaaatgt tgtagaaaca ttcgtttttt tcaatgaaaa aggtgtaatt
    12361 tctataaaaa atagcgtttt taatcaaaat atgctaaaat tatataaaat aaaatgatgg
    12421 aggcttctca tgaaagcgat tattacagtt gtaggtaagg ataaagcggg tattgttgca
    12481 ggtgttgcga ctaagattgc agaacttggt ttgaatattg atgatatcac tcaaacaatc
    12541 cttgatgaat tctttaccat gatggcggtt gtatcatcgg aagataagaa agattttaca
    12601 cacctacgtg ctgaattaga agcttttggt gaatcattaa acgtcaaaat caatatccaa
    12661 agctcagcga tttttgatgc tatgcacaac ttataagata ggggtagttg aaaatggata
    12721 ttaaacaggt tacagaaacc attgctatga ttgaggagca gaactttgat gttcgtacta
    12781 tcaccatggg aatttcactt ctagactgta tcgattcaga tattgataag gcagcagaaa
    12841 aggtatacaa caagattgtt tctaaggcta agaacttggt agctgttggt gacgaaattg
    12901 cggctgaact tggtattccg attgttaata aacgtgtttc tgttactccg atttcaatta
    12961 tcggtgcggc gacagatgcg acagattatg taccgtttgc tagggcacta gaccgtgcag
    13021 ctaaggaaat tggcattaac tttattggtg gtttctctgc attagttcaa aagggctacc
    13081 aaaaaggtga tgagattctt attgattcta tcccacgtgc gcttgctgag actgattttg
    13141 tctgctcatc tgttaatatt ggttcaacaa aaactggtat taacatgaca gcggtacgtg
    13201 atatgggacg tatcattaaa gaggcttctg aggcagatcc aatgggtcca ggtaaattgg
    13261 ttgtctttgc taatgcggtt gaagataatc catttatggc aggtgccttc cacggtgttg
    13321 gtgaggctga cgttgtaatc aatgttgggg tttcaggtcc tggtgttgtg caacgtgctg
    13381 ttgagaaggt tccaggtgaa agttttgatg ttttagctga aacagttaag aaaactgcct
    13441 ttaaaatcac acgtgtaggg cagttggttg gtcaaatggc tagcgaacgt ctaggtgtcg
    13501 agtttggtat tgtagacttg tctcttgcac caactccagc agtaggtgat tcggtagctc
    13561 gtgtacttga agccatgggg cttgaagttg ttggtacgca tggtactact gcggctctag
    13621 ctcttcttaa tgaccaagtt aaaaaaggtg gtatcatggc atgtaaccag gtcggtggtt
    13681 tgtcaggtgc ctttatccca gtttctgaag atgaaggaat gattgcagca gttcaatctg
    13741 ggcatatcaa ccttgaaaaa ttggaagcca tgacggctat ctgttctgtt ggtctagaca
    13801 tgattgccat tcctgctgat acgccagata caacaattgc ggccatgatt gccgatgaag
    13861 cggctattgg tgtcattaat cagaaaacaa cagctgttcg tattattcct tatggtaagg
    13921 aaggggacat gttggaactt ggaggt
//
