LOCUS       c00016_gnlPro..        12614 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PFGKIKKO_23.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 17:34:12
            Original ID  :: gnl|Prokka|PFGKIKKO_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 22924
            Orig. end    :: 35538
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12614
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[32924:35537]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12613
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..12614
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12614
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2150..5731)
                     /locus_tag="ctg16_34"
                     /transl_table=11
                     /translation="LAGHDVQYGKHRTRRSFSRIKEVLGLPNLIEIQTDSFKEFLDTGL
                     KEVFEDVLPISNFTDTMELEFVGYELKEPKYTLEEARIHDASYSAPIFVTFRLINKETG
                     EIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVI
                     PNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGDSELVRNTIE
                     KDIHKNPADSRTDEALKEIYERLRPGEPKTADSSRSLLVARFFDPRRYDLAAVGRYKLN
                     KKLNIKTRLLGQTIAENLVDPETGEILVEAGTEMTRDVIDSIAEHLDGDLNKFVYTPND
                     YAVVTEPVVLQKFKVVAPNDPDRVVTIVGNANPDDKVRALTTADILAEMSYFLNLAEGI
                     GKVDDIDHLGNRRVRAVGELLANQFRIGLARMERNVRERMSVQDNEALTPQQIINIRPV
                     TAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGR
                     MCPIETPEGPNIGLINNLSTYGRLNKYGFIQTPYRKVDRATGKVTNEVVWLTADEEDEY
                     IVAQANSKLNEDGTFAEEIVMGRHQGVNQEYPSHLVDFVDVSPKQVVAVATACIPFLEN
                     DDSNRALMGANMQRQAVPLIDPKAPFVGTGMEYQAAHDSGAAVIAKHDGKVVYSDADKV
                     EVRREDGSLDVYTIQKFRRSNSGTAYNQRTLVKVGDIVEKGDFIADGPSMEGGEMALGQ
                     NPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEFESETRDTKLGPEEITRELPNV
                     SEEALKNLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDT
                     SLRVPHGGDGVVRDVKIFTRANGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGV
                     VSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARNLGIYIATPVFD
                     GASSEDLWDTVREAGMDSDAKTILYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARS
                     VGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNILQEILTYKSDDVNGRLKAYE
                     AITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDYEVELRDLDEGEDDDVMHVDD
                     LEKARVQQAKEAAELEKAKEEALDKTE"
     CDS             complement(6094..8517)
                     /locus_tag="ctg16_35"
                     /transl_table=11
                     /translation="MNFEKIINYFRRLGKVFREKFAGLNFKKRDKSLKVRKAGIKSKWN
                     RKQAEKSPEDRVTVLDMADVFLKTLKLLSDFFYVVIIVLTLFGAGLGLGYLGSQIQSVP
                     LIKDKTLLNQIGEVSLVSSMSYSDSKKIADIDTDLLRTPIESDAISNNVKNAIIATEDE
                     NFNKHKGVVPKAVFRALVSSVLGVGSSSGGSTLTQQLIKQQVTGDTPTFKRKAAEIIYA
                     LQLERHASKNEILTDYLNVSPFGRNNKGKNIAGIEEAAQGIFGVSAADLTVPQAAYLAG
                     LPQSPIVYSPYTADGQLKNEKDLSYGLARQKDVLYNLYRGGYLDKSQYESYKSYDVTKD
                     FKAGENPDAVSHDYLYYSVMSEAQDIMYDYLVKRDKVSSQDLKNDKTKEAYREMALREL
                     QTGGYHVKTTIDNAVYHAMQDTANKYGDLLDQGGNNGVEVGNVLMDNVTGAILGFVGGR
                     NYENNQNNHAFDTARSPGSSIKPIIAYGIAIDQGLMGSSSILSNYPTNFTGGTPILHDG
                     DKGTAMMNLQEALNTSWNIPAFWTYQMLQHHDVDVEGYMTKMGYKIANYNIEGLPLGGG
                     IETTVAQQVNAYQMLSNGGVYEKGYMIDSITDSTGEVIYQHKSKGVQVFTRATASIMDN
                     LLKEVVVKGATTQFYSELKNVNGAAASADWMGKTGTTDNFTDAWLVVSTPGITLGGWAG
                     YDDNAPTNSKTGYTYNAQYMARLTSAIYNANPDIFKTGDKFNIDSSAIKASVLKSTGLK
                     PATVSVNGRNVSVSGEMVDSYWAKNGPGDTIYKFAIGGTDSDYQKAWSSILGEH"
     CDS             8619..9875
                     /locus_tag="ctg16_36"
                     /transl_table=11
                     /translation="MTIFEELKARGLIFQTTDEEALVKAFEEGPVSFYTGYDPTADSLH
                     LGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVEGWVEKIQGQ
                     LSRFLDFENGDNKAVMVNNYDWFGSVSFIDFLRDVGKYFTVNYMMSKESVKKRIETGIS
                     YTEFAYQIMQGYDFYELNAKYGVTLQIGGSDQWGNMTAGTELLRRKADKSGHVITVPLI
                     TDSTGKKFGKSEGNAVWLDATKTTPYEMYQFWLNVMDDDAVRFLKIFTFLSLEEIEEIG
                     KEFDQARHQRLAQKVLAREVVTLVHGKEAYEQAVHITEQLFAGNLKALSARDLKVALNG
                     VPTYEISADENLNIVELLVNAKISPSKRQAREDVQNGAIYINGERVQDLDYTLSDTDKI
                     DNEITVIRRGKKKNFVLTY"
     CDS             complement(10001..11023)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_37"
                     /sec_met_domain="IlvN (E-value: 3.9e-77, bitscore: 248.8,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.7e-65, bitscore: 211.1,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVQMEYEKDVKVPALDGKKIAVIGYGSQGHAHSQNLRDTGHDVI
                     IGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGNAV
                     GFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTFEEGFGVPALYAVYQDATGNAKD
                     IAMDWCKGIGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIETGFEVLTEAGYAPE
                     LAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEFGDYVSGPRVITEQVKENMKAVLAD
                     IQNGKFANDFVNDYKAGRPKLTAYREEAANLEIEKVGAELRKAMPFVGQNDDDAFKIYN
                     "
     CDS             complement(11098..11574)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_38"
                     /sec_met_domain="ALS_ss_C (E-value: 1.4e-28, bitscore:
                     90.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATENPDVSR
                     ITIIIDVNSHNEVEQIIKQLNRQIDVIRIRDITDVPHLEREVILVKVSAPTSKRAEILA
                     IIQPFRASVVDVAPSSITIQMTGDAEKSEALLRVIRPYGIKNIARTGATGFTRD"
     CDS             complement(11567..12613)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_39"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-47, bitscore:
                     152.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GGVAYSESAKELVAFAERYQIPVVTSLLGQGTIATSHPLFLGMGG
                     MHGSYAANIAMTDADFMIAIGCRFDDRLTGNPKTFAKNAKVVHIDVDPAEIGKIIAVDL
                     PVVGDAKQALEMLLAEPVVKNNTEKWIEKVKKDKERVRSYDKKERMVQPQAVIERIGEL
                     TDGDAVVVTDVGQHQMWTAQYYPYQNERQLVTSGGLGTMGFGVPAAIGAKIANPDKEVI
                     LFVGDGGFQMTNQELAILNIYKVSIKVVMLNNHSLGMVRQWQESFYEGRTSESVFNALP
                     DFQLMAQAYGIKSYKFDNPETIDQDLEVIKEDVPMFIEVDISRKEHVLPIVPAGKSNHE
                     MLGVKFNA"
ORIGIN
        1 ttcttcaaca cggtggtgag cagcatcgat aatttcttgt ttgttatcaa taactgggat
       61 atcggcgata cccactgtca atccagcaag tgttgagtag tagtaaccaa ggtctttcaa
      121 acggtcaagg aaagctgatg tttcagttgt acgaagacgt ttgaagattt cagcaatgat
      181 gttaccaaga tgtttcttct tgaatggcgc attaatttcc aaactatcga taactgtttg
      241 gatatcttgg cccggttcaa ggaagtattt atctggtgta ctatctgtca agttctcatt
      301 tgttgtttct tgaagatatg gaatttctga tggaatgatt gagttgaaga gaatcttacc
      361 aacagttgtt actaagattt tgtgaagttg gttttctttc caaggtttat caggcatgct
      421 atcgactgca atacctacac ggctatgcaa gtgaacataa ccattatgat aagccataac
      481 tgcctcatca atatccttga agatcatacc ttcaccttca cggccttcat cttccattgt
      541 caagtaatag ttaccaagaa ccatatcctg agatggtgtt acgactggtt taccgtcttt
      601 agggttaagg atgtgttctg ccgcaagaag gagcaaacgt gcttcagctt gagcttcttc
      661 agacaatgga acgtggatgg ccatttggtc accgtcaaag tcggcattgt aggcctcaca
      721 taccaatggg tgaagacgaa gagccttacc atcaatcaag acgggttcaa aggcctggat
      781 acccaaacgg tggagggtag gtgcgcggtt aagaagcact gggtgttcct tgataacatc
      841 ttcaagaata tcccaaatac gttcatcacc acgctcaacc atacgtttag cagctttcac
      901 gttacctgcg tattcacgcg caacgatttc acgcataaca aatggtttga aaagttcgat
      961 ggccatcaaa cggggcacac cacattgata cattttaagt gttggaccaa cggcaataac
     1021 ggaacggcca gagaagtcga cacgtttacc aagcaagttt tgacggaaac gaccttgttt
     1081 acctttaagc atgtggctca aagatttaag tggacgacta cctggtccag taattggacg
     1141 accacgacgt ccattatcaa taagagcgtc taccgcttct tgcaacatac gtttttcgtt
     1201 ttgcacgatg atacctggag cacccaactc aagcaaacga gccaaacggt tgttacggtt
     1261 gataacacga cggtagaggt cgttcaagtc agatgctgca aaacgtccac cgtccaattg
     1321 aaccatcgga cgaagatctg gtggcaatac tggcaatatg ttaagcacca tccattctgg
     1381 tttattacca gacttgtaaa aggcatcaag aacgtccaaa cgacgaactg ctttaaaacg
     1441 tttttgacca gttgctgtct tcaactcttc tttgagttca gcaatttcgg cttccaaatc
     1501 tacttgtttc aagagatctt ggatagcttc tgcacccatt ttagcgacaa atgaaccctg
     1561 accatactct tgcaattttt cacgatattc acgttcagtc aagagagatt ttggctcaag
     1621 cggtgtttcc tttggatcga taaccacgta agctgcgaag taaataactt cttcaagtgc
     1681 acgaggactc atatccaaag tcaatcccat acgagaaggg attcccttga agtaccagat
     1741 atgtgatact ggtgctttca actcgatgtg acccatacgt tcgcgacgaa ccttagcacg
     1801 tgttacttca acaccacagc ggtcacaaac gatcccttta taacggatac gtttgtattt
     1861 cccacacgca cattcccagt ctttagtagg accaaagatc acttcgtcga acagaccttc
     1921 acgttctggt ttgagcgtac ggtagttgat tgtttcaggt ttcttaacct caccataaga
     1981 ccatgaacgg accttagttg gtgaagctag tgtaatttgc atacttttaa atcgatttac
     2041 gtcaaccact agtattacct ttcttttgtt ctattgacaa tagcagcgct attttcacct
     2101 ttatcagcta ccttagcaga gaaatttaac tccctctcta aagcttattt tattctgttt
     2161 tatctaaagc ttcttcttta gctttttcta attcagcagc ttctttggct tgttgtacac
     2221 gtgctttttc aagatcatca acgtgcatga cgtcatcatc ttcaccttca tcaagatcac
     2281 gcaattcaac ttcatagtca tcctcatcaa gaacacgcat atcaagacca agtgattgca
     2341 attctttaac gagcactcgg aatgattctg gtacacctgg ttttggaatt ggttttcctt
     2401 tagtgatagc ttcataggct ttcaaacgtc cgttaacgtc atctgacttg taagtcaaga
     2461 tttcttgaag aatgtttgaa gcaccataag cttcaagagc ccaaacctcc atctcaccga
     2521 aacgttgtcc accaaattgt gctttaccac caagaggttg ttgggtaacg agtgagtaag
     2581 gacctaccga acgagcgtga agtttatcat caaccatgtg gtgaagtttg atcatgtaca
     2641 tgacaccaac tgacacacgg ttatcaaatg gctctcctgt acgtccatcg taaaggattg
     2701 tcttagcatc actgtccata ccagcttcac gaacagtatc ccagagatct tctgagcttg
     2761 ccccatcaaa gactggtgtt gcgatgtaga tacccaagtt acgagcagcc ataccaaggt
     2821 gaagttccat aacctgacca atgttcatac gtgatggcac cccaagaggg ttcaacatga
     2881 tgtcaactgg tgtaccgtct ggaaggtaag gcatgtcttc aacaggaaca atacgagaaa
     2941 caaccccttt gttaccgtga cgaccagcca tcttatctcc gaccttgatt ttacgttttt
     3001 gagcgatgta aacacgaaca agcatgttaa cacctgattg caattcatca ccgtttgcac
     3061 gtgtaaagat tttaacatca cgaacgacac catcaccacc atgaggtaca cggagtgatg
     3121 tatcacgtac ttcacgagat ttatcaccaa agatagcatg gagaagacgt tcttcagcag
     3181 aaaggtcttt ttcaccctta ggtgttacct taccaacaag aatatcacct tctttaacct
     3241 cagcaccgat acggataata cccatttcgt caaggttttt aagggcttct tcactaacgt
     3301 ttggcaattc acgtgtgatt tcttcaggtc caagctttgt atcacgtgtt tctgattcga
     3361 attcttccaa gtgaacagat gtataaacat cgtctttcac taggcgttca ctcatgataa
     3421 cagcatcctc gaagttgtaa ccttcccatg tcatgtatgc gacaataggg ttttgaccga
     3481 gggccatttc tccaccttcc atagatggac catcagcgat aaaatctcct ttttcgacaa
     3541 tatcaccaac cttaaccaaa gtacgttggt tatacgcagt acctgagttt gaacgacgga
     3601 atttttgaat agtatagacg tcaagagaac catcttcacg acgaacttca accttatcgg
     3661 catcagaata gacaacttta ccatcatgtt tagcgataac tgcagcacct gaatcgtgag
     3721 cagcttgata ttccatacca gtaccaacaa atggtgcttt tggatcaatc aatggcacag
     3781 cttgacgttg catgttggca cccatgaggg cacggttaga gtcatcgttt tccaagaaag
     3841 gaatacatgc tgtcgcaacg gcaactacct gtttaggaga aacatccacg aaatctacaa
     3901 ggtgtgatgg gtactcttgg ttaacacctt ggtgacgacc catgacaatt tcttctgcaa
     3961 atgttccatc ttcgttcaat ttagagttag cctgagcaac tatgtactca tcttcttcgt
     4021 cggcagtcaa ccaaaccact tcgtttgtta ctttaccagt tgcacggtca accttacgat
     4081 atggtgtttg aatgaaaccg tacttgttaa ggcgtccata tgtagacaag ttattgatca
     4141 aaccaatgtt aggtccttca ggtgtttcaa ttggacacat acgaccgtag tgcgtgtaat
     4201 gcacgtcacg aacttcatat ccggcacggt cacgtgtcaa accaccaggt cccaaggctg
     4261 acaaacgacg tttgtgtgac aactctgaca atgggttgtg ctggtccatg aactgtgaca
     4321 actgtgaaga accgaagaat tctttaacag ctgcagttac aggacgaata ttgatgattt
     4381 gttgtggtgt caaggcttca ttatcttgaa ctgacatacg ttcacgcacg tttcgttcca
     4441 tacgagccaa accaatacgg aattggttag caagcaattc accaacggca cggacacgac
     4501 ggttaccaag gtggtcgata tcatctactt taccgatacc ttcagcaagg ttgaggaagt
     4561 agctcatttc agccaagata tccgctgttg tcaaagcacg aactttatca tctggattgg
     4621 cattaccaac aattgtaacc acacgatctg gatcatttgg tgcaacgacc ttgaattttt
     4681 gaagaacaac aggttctgta accactgcat aatcgtttgg tgtgtataca aatttgttca
     4741 aatcaccgtc caagtgttct gcgattgaat caatcacatc acgtgtcatt tcagtcccag
     4801 cttcaacaag gatttcacct gtttcaggat ctaccaagtt ttcagcaatt gtttgtccca
     4861 aaagacgtgt cttgatgtta agttttttgt taagtttgta acgaccaaca gcagccaagt
     4921 cgtaacgacg tgggtcaaag aaacgagcta caagcaagct acgtgagctg tcagcagttt
     4981 ttggttcacc tggacgaagt ctttcataaa tttctttaag cgcttcatca gtacgtgaat
     5041 ctgctggatt tttgtggata tctttttcaa tagtgttacg aaccaactcg ctatcaccaa
     5101 agatatcaac aatttcgtca tcacctgaga atccaagtgc acgcacaagc gttgtgaatg
     5161 gaatcttacg cgtacggtcg atacgagtgt aggcaatgtc ttttgaatca gtttcaagct
     5221 caagccatgc cccacggtta ggaataactg ttgatccgta acccacttta ccgtttttat
     5281 cgaccttatc gttaaagtaa acaccaggtg agcgcaccaa ctgagaaacg ataatacgtt
     5341 caccaccatt gatgataaaa gtacccatct cagtcataat tgggaaatct ccgaagaaga
     5401 cttcctgagt tttaatttca ccagtttctt tgttaataag acggaaagtc acaaagattg
     5461 gtgctgagta tgatgcatca tggatacgag cttcttcaag tgtatactta ggttccttca
     5521 attcataacc aacaaattcc aattccatag tgtctgtgaa gtttgaaata ggaagtacat
     5581 cctcaaaaac ctctttaaga ccagtatcta agaattcttt gaatgaatcc gtttggattt
     5641 caatcaagtt tggtaaacca agaacttctt tgattcttga aaaactacga cgggtacgat
     5701 gcttcccgta ttgaacgtca tgtcctgcca agtcttctac tccttttcta catttgagac
     5761 ctgctttgca agtcgtgcac tttaaatatt tgtctcctgc cttttttggt tgcttgtccc
     5821 gataacaagt gattagatat taacatcgac ttatcggatt aacgataagc gataacttta
     5881 atatgtgaat ttttagaact tttaaatatt cattacaaaa tccaaaaacc ctaaaaataa
     5941 gcacaaaaat agcagctaaa tctgaccgaa aaaacgttga tttaactgct gtatctcttg
     6001 attggacaat atttcaatca aataagacga caaatagttt tgtctatatt gtacctaaat
     6061 tttaactatt ttgcaagtat tatttgagac agcctaatgt tctccaagaa tactagacca
     6121 agctttttgg tagtcactat ccgttccacc aatggcaaac ttgtagattg tatcgccagg
     6181 tccattttta gcccaataac tatcaaccat ttcaccactt acggagacat tacggccatt
     6241 gaccgatacc gttgctggct taaggcctgt cgacttgagc acacttgcct taatggcgct
     6301 tgaatctata ttaaacttat ctcccgtttt gaaaatatct ggattagcat tatagatggc
     6361 tgaagtcaaa cgagccatat attgggcatt gtaagtgtaa cccgttttag aattggtagg
     6421 tgcattgtca tcataaccag cccaaccccc aagggtaatg ccaggcgtcg acacaaccaa
     6481 ccaagcatca gtaaagttat cagtcgtccc tgttttaccc atccagtcag ctgaggccgc
     6541 tgcaccattg acatttttca actccgaata aaattgggtt gtcgctccct taaccacaac
     6601 ttctttaagt aagttatcca taatgctagc cgtagccctt gtaaagacct gaaccccttt
     6661 agatttatgt tgataaataa cctcaccagt gctatcagta atactatcaa tcatataacc
     6721 tttttcataa acaccgccat ttgaaagcat ttgataggcg tttacctgct gagcaacagt
     6781 agtttcaatc ccaccaccaa ggggcagacc ctcaatattg tagttagcaa tcttatatcc
     6841 catcttggtc atatagccct caacgtcaac atcatgatgt tgaagcattt gataggtcca
     6901 aaaggcagga atattccacg acgtattaag cgcctcttgc aaattcatca tggccgttcc
     6961 cttatcgcca tcatgaagaa tcggtgtccc acctgtaaaa ttagttggat aatttgaaag
     7021 gatacttgag ctacccatta aaccttggtc aatggcaatt ccataagcaa taataggctt
     7081 aatagaagat ccaggagaac gagcagtatc aaaggcatgg ttattctggt tattctcata
     7141 attacgacca ccaacaaatc ctaaaatcgc tccagtcaca ttgtccatga gtacatttcc
     7201 aacttcgacc ccgttatttc caccctgatc aagtagatct ccatatttgt tcgcagtatc
     7261 ttgcatcgca tggtagacag cattgtcaat tgttgtctta acatgataac cacctgtttg
     7321 tagctctcgg agagccatct cacggtaggc ttcctttgtc ttatcatttt tcaaatcttg
     7381 acttgatacc ttgtcacgct tcaccaaata atcatacatg atatcttgag cttcagacat
     7441 gactgaatag tacaaatagt catgactgac agcatctgga ttctcaccag ccttgaaatc
     7501 tttagtaacg tcataactct tataactttc gtattgtgac ttatctaggt aaccgcctcg
     7561 atagagattg tatagcacat ctttctgacg tgccaagcca taggaaagat ctttttcatt
     7621 ttttagttga ccatccgcag tatagggtga atagacaatc gggctctgtg gtaaacctgc
     7681 cagataagct gcctgaggaa ctgtcaaatc tgcagcagag accccaaaga tcccttgtgc
     7741 agcctcttcg ataccagcaa tatttttccc cttgttgtta cgaccaaaag gagaaacatt
     7801 cagataatca gttaaaattt catttttcga agcatgacgt tccagttgta gtgcatagat
     7861 aatctctgcc gctttacgtt taaatgttgg agtatctcct gtaacctgtt gttttatcaa
     7921 ctgctgtgtt agggttgaac caccactaga ggaacctacc cccaagactg aggataccaa
     7981 ggctctaaag acagcttttg gtacaacccc cttatgctta ttgaaatttt catcctcagt
     8041 agcaataatg gcatttttaa cattattaga aattgcatca ctttcaatag gagttctaag
     8101 caggtccgta tcaatatcag caatcttttt agaatcagaa taactcatcg aagacaccaa
     8161 actaacctcg ccaatctgat tcaacaaggt tttatcctta atcaatggaa cagactgtat
     8221 ctgactgccc agataaccca agccaagccc agcaccaaac aaggttaaga cgataatgac
     8281 cacataaaag aaatcagaca agagctttaa tgtctttaaa aaaacatcag ccatgtctaa
     8341 gactgtcact ctgtcttcag gcgacttctc cgcttgctta cgattccact tagatttaat
     8401 tccagccttc cttactttca aagatttatc tcttttttta aaattgaggc cggcaaactt
     8461 ttcacgaaaa accttcccta accgtctaaa ataatttatt attttttcaa aattcataga
     8521 aatacctcaa ggcctattat agcaaacttt gacaaagctt gcatagggtt gctttctttt
     8581 ggtataatgg tgcagaatat actttactgg agaatatcat gacaattttt gaagaactaa
     8641 aagcacgtgg cttgattttt caaaccacag atgaagaagc ccttgtaaaa gcctttgaag
     8701 aagggccagt ctcattctac accggttatg acccaacagc agacagtctc caccttggac
     8761 acctcgtcgc tatccttact agtcgtcgcc ttcaattggc tggccacaaa ccttacgccc
     8821 tcgttggggg tgcgacaggt ttgattggtg acccatcatt taaagatgct gagcgtagcc
     8881 tccaaaccaa agaaaccgtt gaaggttggg tagaaaaaat ccaaggccaa ctctctcgct
     8941 tccttgattt tgaaaatggt gataacaaag ccgttatggt caacaactat gactggtttg
     9001 gttcagttag tttcatcgat ttcttgcgtg atgtcggtaa atacttcaca gttaactaca
     9061 tgatgagcaa ggaatctgtt aagaaacgta tcgaaacagg tatctcttac actgagttcg
     9121 cttaccaaat tatgcaaggt tacgacttct atgaactcaa tgctaaatat ggcgtaaccc
     9181 tacaaattgg tggttctgac caatggggta acatgacagc aggtactgag ctcttgcgtc
     9241 gtaaagcgga caaatctgga cacgtaatca ccgttccact tatcacagat tcaactggta
     9301 aaaaattcgg caaatctgaa ggcaacgctg tctggcttga cgctactaag acaacacctt
     9361 acgaaatgta ccaattctgg cttaacgtta tggacgatga tgccgttcgt ttcttgaaaa
     9421 ttttcacttt cttgtcactt gaagaaatcg aagaaatcgg taaagaattt gaccaagctc
     9481 gtcaccaacg tttagcacaa aaggttctgg ctcgcgaagt tgttactttg gttcacggta
     9541 aagaagccta tgaacaagct gttcacatca ccgaacaact cttcgctggt aaccttaaag
     9601 ccctctcagc acgtgacctt aaagttgccc tcaatggtgt cccaacctat gagatttcag
     9661 cagatgaaaa tcttaacatt gttgaacttc tcgtcaatgc taaaatttca ccatctaaac
     9721 gtcaagcacg tgaagacgtg caaaacggtg ctatctatat caacggtgaa cgcgtgcaag
     9781 acttggatta cactctttca gataccgata agattgacaa tgaaatcact gttatccgtc
     9841 gcggtaagaa gaaaaacttt gttttaactt actaatttat gaccattctc actccctagt
     9901 ggagtgattt tttttacaca caaagccata agcttaacac ctaaccactt tcttaagaac
     9961 acaaaaaacc agcactaggc tggtttttga gactatcaca ttagttatag attttgaatg
    10021 catcatcgtc gttttgacca acgaatggca ttgctttacg caattcagca ccaacttttt
    10081 cgatttcaag gttagcagct tcttcacggt aagcagtaag ttttggacgt ccagctttgt
    10141 agtcgttaac gaagtcatta gcgaatttac cattttggat atcagcaaga actgctttca
    10201 tgttttcttt aacttgttca gtgataacac gtggacctga tacatagtca ccgaattcag
    10261 cagtgttaga aattgattga cgcattttct tgaatccacc ttcgtaaatc aagtcaacga
    10321 ttaatttcat ttcgtgaagt acttcaaagt aagccaattc tggtgcatat ccagcttcag
    10381 tcaagacttc aaaaccagtt tcgataaggg cagtcaaacc accacaaaga actgcttgtt
    10441 caccaaacaa atcttcttca gtttcttctt tgtatgttgt ttcaagaaga cctacacgtg
    10501 ctgcaccaat acctttacac cagtccatag cgatgtcttt agcgttacct gtggcatctt
    10561 ggtatactgc gtaaagggca ggtacaccaa aaccttcttc aaatgtacga cgtaccaagt
    10621 gacctggtcc tttaggtgca cacataaata catcaacatc tgctggtact ttaataaatt
    10681 caaagtggat gttgaaaccg tgagcaaaac caacagcgtt accagcttca agatttggag
    10741 cgatttctgc ttcgtaaagt tcttgttgga tttcgtctgg agccaaaatc atgataacat
    10801 cagccaattt agttgcttct gctactgtgt aagtatcaaa accatcttct ttagctttat
    10861 caaatgattt acctggacga acaccgatga taacatcgtg acctgtatca cgcaagtttt
    10921 gtgagtgagc gtgaccttgt gaaccgtaac cgataacggc gattttttta ccatcaagtg
    10981 ctggtacttt tacgtctttt tcatattcca tttgaactgc catagtagta tatctctttt
    11041 ctaaaataat atttaattgc ctttttaagg ctaggttaac aaatttataa tggattttta
    11101 atcacgggta aatccagtag cacccgtacg agcaatattc ttgataccgt aaggtcgaat
    11161 aactcgtaga agcgcctcac tcttttcagc atctccagtc atctggatag tgatagagct
    11221 tggtgcaaca tccaccaccg aagcacggaa aggttgaatg attgccaaga tttcagcacg
    11281 tttagaagtt ggtgccgaca ccttaaccaa gataacctca cgttccaagt ggggtacatc
    11341 agtgatgtca cgaatgcgaa tcacatcaat ctgacgatta agctgtttaa taatctgctc
    11401 aacctcatta tgagaattca catcaatgat aattgtaata cgtgaaacat caggattttc
    11461 cgttgctcca acggaaatac tctcaatatt gacctgacgg cgtgaaagca ctccagtgaa
    11521 acggttaaga acacctgatc ggttctgaag tttagctgtt aacattctac gcattgaact
    11581 tcacccccaa catttcatga ttactcttac cagctggaac gattggcaaa acatgctctt
    11641 tacgagaaat atcaacctcg atgaacattg gcacatcctc tttgataact tccaaatcct
    11701 gatcaatcgt ttctggatta tcaaacttat aagacttaat cccataagct tgagccatca
    11761 gttgaaaatc aggaagagca ttaaagacag actctgatgt acgcccttcg tagaaggact
    11821 cttgccattg acgtaccata ccaagtgagt ggttattcaa cataacaacc ttgattgaca
    11881 ccttgtaaat atttaaaata gccaattctt ggttcgtcat ttggaaacca ccatcaccaa
    11941 caaagaggat aacttcttta tcaggattag caattttagc accaattgct gctggaacac
    12001 caaatcccat agttccaagg ccacctgatg tcaccaattg acgctcattt tgatatggat
    12061 aatactgagc tgtccacatt tgatgttgcc caacgtcagt gacaacaact gcatcaccat
    12121 cggtcaattc accgatacgc tcgataaccg cctgaggctg taccatacgt tctttcttat
    12181 cgtaagaacg tacacgctct ttatcttttt tgactttttc aatccatttt tcagtgttat
    12241 tcttaaccac tggttctgct aagagcattt caagagcttg cttggcatca ccaacaactg
    12301 gcaaatctac cgcaataatc ttgccaatct cagccggatc cacatcaata tgaacaacct
    12361 ttgcattctt agcaaatgtt tttggattac ctgtcaagcg gtcatcaaaa cgacaaccta
    12421 tggcaatcat aaagtcagca tcagtcatag caatattagc tgcatacgaa ccgtgcatac
    12481 cacccatacc caaaaagagg ggatgactag tagcaattgt tccctgacct agaagacttg
    12541 taacaacagg aatttggtag cgttctgcaa aagcaactag ctccttagca gattcagaat
    12601 aagccactcc acct
//
