Select genomic region:
Overview
7.1
7.2
11.1
16.1
39.1
55.1
66.1
66.2
69.1
69.2
71.1

### Identified primary metabolite regions

c00007_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_7)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 7.1 | Putrescine2spermidine | Aliphatic_amine | 24,869 | 48,117 | Putrescine2spermidine E. rectale | SPRM | 100%
Region 7.2 | Rnf_complex | E-MGC | 68,413 | 91,810 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 14%

c00011_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_11)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 11.1 | Acetyl-CoA_pathway | SCFA | 197,648 | 233,682 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 61%

c00016_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_16)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 16.1 | Fumarate2succinate | SCFA | 18,030 | 46,382 |

c00039_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_39)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 39.1 | TPP_AA_metabolism | Putative | 1 | 12,221 |

c00055_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_55)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 55.1 | succinate2propionate,Rnf_complex | E-MGC | 99,755 | 138,495 | Rnf complex C. sporogenes | RNF | 100%

c00066_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_66)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 66.1 | Others_HGD_unassigned | Putative | 25,436 | 44,718 |
Region 66.2 | Others_HGD_unassigned,TPP_AA_metabolism | Putative | 74,327 | 107,519 |

c00069_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_69)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 69.1 | GR_AA_metabolism,Pyruvate2acetate-formate | SCFA | 22,238 | 60,109 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%
Region 69.2 | PFOR_II_pathway | SCFA | 64,210 | 87,746 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%

c00071_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_71)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 71.1 | GR_eut-pdu-related | Putative | 70,558 | 106,782 | Propanediol degradation S. enterica | PDU | 37%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 7.1 | Putrescine2spermidine | Aliphatic_amine | 24,869 | 48,117 | Putrescine2spermidine E. rectale | SPRM | 100%
Region 7.2 | Rnf_complex | E-MGC | 68,413 | 91,810 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 14%
Region 11.1 | Acetyl-CoA_pathway | SCFA | 197,648 | 233,682 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 61%
Region 16.1 | Fumarate2succinate | SCFA | 18,030 | 46,382 |
Region 39.1 | TPP_AA_metabolism | Putative | 1 | 12,221 |
Region 55.1 | succinate2propionate,Rnf_complex | E-MGC | 99,755 | 138,495 | Rnf complex C. sporogenes | RNF | 100%
Region 66.1 | Others_HGD_unassigned | Putative | 25,436 | 44,718 |
Region 66.2 | Others_HGD_unassigned,TPP_AA_metabolism | Putative | 74,327 | 107,519 |
Region 69.1 | GR_AA_metabolism,Pyruvate2acetate-formate | SCFA | 22,238 | 60,109 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%
Region 69.2 | PFOR_II_pathway | SCFA | 64,210 | 87,746 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%
Region 71.1 | GR_eut-pdu-related | Putative | 70,558 | 106,782 | Propanediol degradation S. enterica | PDU | 37%

No primary metabolite regions were found in these records:
  c00001_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_1)
  c00002_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_2)
  c00003_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_3)
  c00004_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_4)
  c00005_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_5)
  c00006_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_6)
  c00008_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_8)
  c00009_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_9)
  c00010_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_10)
  c00012_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_12)
  c00013_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_13)
  c00014_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_14)
  c00015_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_15)
  c00017_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_17)
  c00018_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_18)
  c00019_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_19)
  c00020_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_20)
  c00021_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_21)
  c00022_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_22)
  c00023_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_23)
  c00024_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_25)
  c00026_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_30)
  c00031_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_31)
  c00032_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_32)
  c00033_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_33)
  c00034_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_34)
  c00035_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_38)
  c00040_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_40)
  c00041_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_41)
  c00042_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_43)
  c00044_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_44)
  c00045_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_45)
  c00046_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_46)
  c00047_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_47)
  c00048_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_48)
  c00049_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_49)
  c00050_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_50)
  c00051_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_51)
  c00052_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_52)
  c00053_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_53)
  c00054_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_54)
  c00056_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_56)
  c00057_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_57)
  c00058_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_58)
  c00059_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_59)
  c00060_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_60)
  c00061_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_61)
  c00062_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_62)
  c00063_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_63)
  c00064_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_64)
  c00065_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_65)
  c00067_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_67)
  c00068_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_68)
  c00070_gnlPro.. (original name was: gnl|Prokka|AIHJECGG_70)

Compact view
c00007_gnlPro.. - Region 1 - Putrescine2spermidine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 24,869 - 48,117 nt. (total: 23,249 nt) Show pHMM detection rules used
Putrescine2spermidine: (minimum(2, [AdoMet_dc, Spermine_synt_N, Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00007_gnlPro.. - Region 2 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 68,413 - 91,810 nt. (total: 23,398 nt) Show pHMM detection rules used
Region on contig edge.
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00011_gnlPro.. - Region 1 - Acetyl-CoA_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 197,648 - 233,682 nt. (total: 36,035 nt) Show pHMM detection rules used
Acetyl-CoA_pathway: (CdhC and CdhD and minimum(8, [CbiA, FTCD_C, FTHFS, FeS, Fer2, GCV_H, MTHFR, MTHFR_C, Prismane, Pterin_bind, Pyr_redox_2, Pyr_redox_dim, RACo_C_ter, THF_DHG_CYH, THF_DHG_CYH_C]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00016_gnlPro.. - Region 1 - Fumarate2succinate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 18,030 - 46,382 nt. (total: 28,353 nt) Show pHMM detection rules used
Fumarate2succinate: (Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or Fer4_7 or SucD_FumR))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00039_gnlPro.. - Region 1 - TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 12,221 nt. (total: 12,221 nt) Show pHMM detection rules used
Region on contig edge.
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00055_gnlPro.. - Region 1 - Rnf_complex,succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 99,755 - 138,495 nt. (total: 38,741 nt) Show pHMM detection rules used
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00066_gnlPro.. - Region 1 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 25,436 - 44,718 nt. (total: 19,283 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00066_gnlPro.. - Region 2 - Others_HGD_unassigned,TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 74,327 - 107,519 nt. (total: 33,193 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00069_gnlPro.. - Region 1 - GR_AA_metabolism,Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 22,238 - 60,109 nt. (total: 37,872 nt) Show pHMM detection rules used
GR_AA_metabolism: (minimum(1, [Gly_430_pcre, Gly_8-9_TMA, Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline, PFL_toluene]) and not NRDD and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00069_gnlPro.. - Region 2 - PFOR_II_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 64,210 - 87,746 nt. (total: 23,537 nt) Show pHMM detection rules used
PFOR_II_pathway: cds(POR and POR_N and PFOR_II and EKR and Fer4_16 and TPP_enzyme_C)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00071_gnlPro.. - Region 1 - GR_eut-pdu-related
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 70,558 - 106,782 nt. (total: 36,225 nt) Show pHMM detection rules used
GR_eut-pdu-related: (minimum(1, [Gly_430_pcre, Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1, PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2, [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not EutC and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.