LOCUS       c00039_gnlPro..        12221 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AIHJECGG_39.
ACCESSION   c00039_gnlPro..
VERSION     c00039_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 17:37:56
            Original ID  :: gnl|Prokka|AIHJECGG_39
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12221
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12221
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[965:6751]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      966..6751
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..12221
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12221
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..122)
                     /locus_tag="ctg39_1"
                     /transl_table=11
                     /translation="LSKYYSIHEFSKIIGVSAQTLRNWDANGKLHPHHTTVSGY"
     CDS             966..2684
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1e-49, bitscore:
                     157.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQISGNKLLVKALKEEGVEYLFGYPGACTIDISDELYKQDDVKI
                     ILPRHEQALVHEADAYARTTGKVGVCLVTSGPGATNLVTGLATANYDSVPLVCFTGQVA
                     RHLIGNDAFQEVDIVGITRSITKYGVTVRRREDLGRIIKEAFYIARTGRPGPVLIDLPK
                     DVMAELGSAEYPKNVNIRGYKPNTDVHIGQLKRAIKLLNKAKRPLFLAGGGVVISRAHE
                     IFREVVEKTKVPVVTTVMGKGSIPTDHPLYIGNLGMHGAYAANMAVSNCDLLFSIGTRF
                     NDRITGKLHEFAPHAQIVHIDIDTASISRNIQVDIPIVSDAKEAITKMNEYVQECSTGK
                     WLGQISQWKEEHPLKMRPNDVLSPMDILKEINEQFENSIIVTDVGQHQMLVSQYAEITE
                     GKQMIMSGGLGTMGYGLPGGIGAKIGNPDRPVIVISGDGGVQMNIQELATAVLEELPVI
                     LCIFNNEYLGMVRQWQKLFYGKRYAMTNLRAGALSRRTEGMEYPQYTPDFIKLAESYRA
                     KGIRVTKKEEIAAAFKEAKKNTKAPTVIEFIIDPEEMVYPMIKPGGTLEDMIMDC"
     CDS             2703..3389
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_3"
                     /sec_met_domain="ALS_ss_C (E-value: 5.3e-23, bitscore:
                     70.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKGMKKRWISLYVENQVGVLSKISGLFSGKSYNLDSLTVGTTED
                     PTVSRMTIATVSDDETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDSLTVGTTED
                     PTVSRMTIATVSDDETFEQIKKQLNRMIEVIKVIDFTDVFVRMKEILYIKVFNCSREDK
                     AELFQIAETFKAKVIDYGKDSLLLEFVQTATKNDAVVKLIKEEFHRIEVVRGGSVGIES
                     ISMMER"
     CDS             complement(3458..4714)
                     /locus_tag="ctg39_4"
                     /transl_table=11
                     /translation="VKSTERLIFHIDVNSAFLSWESARRVSQGLPDLREIPSCVGGNPK
                     KRTGIVVAKSIPAKKYGIQTGEPVAMALRKCPNLVIVPSDFELYDKCSRAFKAICASFA
                     PVMESFSIDEVFLDMTGTSLIYPDPVAAAHELKDKIHRELGFTVNVGISTNKLLAKMAS
                     DFQKPDRVHTLFPDEIPEKMWPLPIRNLLFLGKASEQKLLNHGIRTIGDLARERASNVQ
                     YWLGEKTGHQLWQYARGIDDSPVKAVPDEAKGFSVETTFNDDITSIEQVFPILLEQCDV
                     LATRMRRKDKKCNCISVTFRTLDFRNRSHQTKLENATDLTDEIYINATRLFKEFWKGQP
                     LRLIGVALTGLTDGTYEQMSLFEDTENKERHRKLDAAMDEIRMKFGNDKITRASIMNSN
                     ARIGRKAKAQMKNEKMEEP"
     CDS             5477..6190
                     /locus_tag="ctg39_5"
                     /transl_table=11
                     /translation="MYLSDIHTHSIASGHGTTCTISDMAKAASKKGLKLLGISDHGPGT
                     LASGTSSYFRSLPFYPRKRFGIDILYGVELNILDSAGHTDLSDELLNNLDYAIISMHRQ
                     NYRSGSVSQNTEAYINAIKHPAVKILGHCDDTHFPVDYETLARAALRENVIFEINEASL
                     APGGYRGDTRANAARILYLCQKYQLPVILSSDSHGKEHVGDFTYAEEFVHQLMFPETLI
                     LNNQLPKLKVFLQTR"
     CDS             6392..6751
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_6"
                     /sec_met_domain="ALS_ss_C (E-value: 1.1e-23, bitscore:
                     73.0, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIATVSDDETFEQIKKQLNRMIEVIKVIDFTDVFVRMKEILYIK
                     VFNCSREDKAELFQIAETFKAKVIDYGKDSLLLEFVQTATKNDAVVKLIKEEFHRIEVV
                     RGGSVGIESISMMER"
     CDS             7126..7761
                     /locus_tag="ctg39_7"
                     /transl_table=11
                     /translation="MNTTTTTTTAATKRSSTLYMVELAMMIAIILLMSFTPLGYLRTPG
                     LSITLLTIPVAVGAIILGPKGGAVCGLAFGATSFYMAVTGSSAFAAALFNINPFGTFIV
                     CIVARVLEGWITGLIFAALYKSPAKKFSYYVASLACPLLNTFFFMGFLCLFFYNTDYIQ
                     GIVSSLGVSNPVVFVAAFVGVQGLIEAGFCFVVGSIVSKALSVALKRA"
     CDS             7886..8851
                     /locus_tag="ctg39_8"
                     /transl_table=11
                     /translation="MSLLKEISITDLSNLRIGHASDYNAQTGVTVLYFPLGAKVGCDIS
                     GGGPASRETPLTSPVTADNPINAIVLSGGSAYGLAAADGVMNYLESQNIGYNTGAALVP
                     LVCQSCIYDLSYGDPKIRPTAKMGEEACRQAFAGTDTRTGNIGAGTGATVGKLYGMKQS
                     MKSGLGIAAVSVKNFQMAAIVVVNALGDIFSPQNGQKIAGLKTPDRSGFLDSVHELYRF
                     MTPHDQFTGNTTIGAVITNGAFSKAELNKIASMTRCAYARCINPVATMADGDSIYAASI
                     GNVSVDINMAGTLAAEVMAQAIQNAIHTSRIQDEEFLKYV"
     CDS             complement(9264..10448)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 78.4; E-value: 1.6e-24)"
                     /gene_kind="transport"
                     /locus_tag="ctg39_9"
                     /sec_met_domain="MFS_1 (E-value: 3.1e-25, bitscore: 78.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNYNRTVQACFIGYVVQAIVNNFVPLLFLTFQGSYGISLQKIT
                     LLVTFNFGIQLLVDLASIGFVDRIGYRASMILAHAMAAAGLILLTVLPECLGDPFVGLL
                     IAVMIYAIGGGLLEVLVSPVVEACPTDNKEKAMSLLHSFYCWGHVGVVLLSTLFFRIFG
                     IANWKYMALVWALIPIANGIFFTRVPIAPLLDEGEKGLTMGELFKKKIFWVLMLMMLCA
                     GASEQAVSQWASTLAEKSFGINKTIGDLAGPMAFAILMGSSRAFYGKFGDKINLERFMQ
                     YSAVLCMVSYLMIAFIPVPALGILGCAVCGLSVGIMWPGTFSMAAASVKRGGTALFALL
                     ALAGDVGCSSGPTYVGMISGALNDNLKLGIFAALIFPVLMIMGIKMIGSLQKYD"
     CDS             complement(10789..11553)
                     /locus_tag="ctg39_10"
                     /transl_table=11
                     /translation="MLNQFSRTELLLGKEAMNKLENSRVAVFGIGGVGGYVCEALVRSG
                     VGTFDLIDDDKVCLTNLNRQIIATRKTVGQYKTEVMRDRILDINPKADVRIHNCFYLPE
                     NAADFDFSEYDYVVDAVDTVTAKIELIMRAKEAGTPVISSMGAGNKLDASAFRVADIYK
                     TKVCPLAKVMRRELKKRGVKKLKVVYSEEQPIRPIEDMAISCRSHCICPPGATHKCTER
                     RDIPGSVAFVPSVVGLIIAGEVIKDLTAEYRR"
     CDS             complement(11547..11744)
                     /locus_tag="ctg39_11"
                     /transl_table=11
                     /translation="MQIMKRLLIKNKRKLWLWFLLLVFLFLACRAAYITGSKAEQTRNN
                     EVEERQADSRSIPNEMEILC"
     CDS             complement(11880..12221)
                     /locus_tag="ctg39_12"
                     /transl_table=11
                     /translation="RVLYFVISYLLICIGIALSNRCGLPIIPTDLFPRELSEIIKVKYS
                     KIKVSFDVICLMITACMTGLILGHINGLGIGTVMAAFTMGKVIGLIGDEMDKHFRFVNF
                     TQHCSLHVQ"
ORIGIN
        1 ctatagccac ttactgtagt atgatgcgga tgaagttttc cattggcatc ccaatttcgt
       61 aatgtctggg cagatacgcc tataattttt gaaaattcat gtatagaata atatttactc
      121 aaagaatcaa ctcctttcaa taatattcta ctctaatatc ttgcaaaact caacatgtgc
      181 ttatatgatt ttataattta tatttaactg ttaataacct tccaaacagc tgtattattt
      241 attttttata tcagcaatat agaaatctgt caattacatt actgttcact ccgttctcag
      301 taacgtagcc aaaattcatt caggaacata aattttacag caattatcca aaacccggtt
      361 gacaatttcc tctctataaa tgtataatgt aacccaagaa aacatttgtc caccctattc
      421 ggacaatgaa tatccctata tcagccaaat gccatgacag ggaggagtac acaaccccgg
      481 gaagcacaga gagaaagcgg tcggtgcgag ctttcgtgaa cgaattgtgg aagtagcccc
      541 cgagcagtga accaaaccgt atatcccgtc tgatccacaa gacctgaacg gacatgccaa
      601 gtaggcttca acgtcagttc cacgttacag gaacacagta tatcagtact gacaaagtgc
      661 agagccagac tctgaataca ggtggtaccg cggaaacatt ttcgccctgg gcaaacaagc
      721 ccagggcgtt ttttactata tttatatatc agggtcaaaa agtcgttcgt gtttgcttta
      781 atctgtcaca tcaaacccgc cgccccaccc tgtattcgcc aatacacagc tcggaaattt
      841 atttgttttc gggtgcattt gcaggagtcg tagtaactct tagtgcctgg accccgaaac
      901 cgcacccgaa aacaaataaa tttccgagcg tcctatacac atacacaaag gaggtttacc
      961 caaatatgaa acaaatatcc ggcaacaaac tcttagtcaa agccttaaaa gaagaaggcg
     1021 tagaatacct cttcggctac cccggagcct gtaccatcga catcagtgat gaactctaca
     1081 aacaggacga tgtcaaaatc atcctccccc gtcacgaaca ggcccttgtc cacgaagccg
     1141 acgcctacgc cagaaccacc ggcaaagtcg gcgtatgtct ggtaaccagc ggtcccggag
     1201 caaccaacct tgtaacagga cttgcaaccg ccaactatga cagcgtacct cttgtatgct
     1261 tcaccggcca ggtagcccgc cacctcatcg gcaacgatgc atttcaggaa gtagacatcg
     1321 taggaatcac cagaagcatc accaaatacg gtgttactgt ccgcagacgt gaagacctgg
     1381 gacgtatcat caaagaagcc ttctacattg cccgcaccgg ccgtccggga cctgtcctta
     1441 tcgaccttcc aaaggacgta atggcagaac tcggcagcgc tgaatatcct aaaaatgtaa
     1501 acatccgcgg atacaaacca aacacagatg tccacatcgg ccagctcaaa cgtgccatca
     1561 aacttttaaa taaagcaaaa cgtcccttat tcctggcagg cggcggtgta gtaatctccc
     1621 gcgcccatga aatcttccgg gaagtagtgg aaaagacaaa agtaccggtt gtcacaaccg
     1681 taatgggaaa aggctctatc cccacagacc atccgctcta catcggaaac cttggtatgc
     1741 atggtgccta tgcagcaaat atggcagtca gcaactgtga tctccttttc tctatcggaa
     1801 ccagattcaa tgacagaatc acaggaaaac ttcatgaatt tgcacctcat gcacagattg
     1861 tacacatcga tatcgacacc gcatctatct ccagaaacat tcaggtagat attcctattg
     1921 tttcagatgc aaaagaagct atcacaaaaa tgaatgaata cgttcaggaa tgctctacag
     1981 gcaagtggct tggccagatc agccagtgga aagaagaaca tccgctgaaa atgcgtccaa
     2041 acgatgtttt aagtccaatg gacattctga aagaaatcaa tgaacagttc gaaaacagca
     2101 ttatcgttac agatgtaggc cagcaccaga tgcttgtttc tcagtatgcg gaaatcacag
     2161 agggcaaaca gatgatcatg tccggcggtc tgggaaccat gggctatggt cttccgggcg
     2221 gtatcggagc caaaatcgga aatcctgaca ggcctgtcat cgttatctcc ggtgacggcg
     2281 gtgtgcagat gaatatccag gagcttgcaa cagcagttct ggaggaactt ccagtaatcc
     2341 tgtgtatctt taacaatgaa tatcttggaa tggtacgcca gtggcagaaa ctcttctacg
     2401 gtaaacgcta cgccatgacc aacctgcgcg ccggagcact ttcccgccgc acagaaggca
     2461 tggaatatcc acagtacaca ccggatttca ttaaacttgc agaaagctat cgcgcaaagg
     2521 gaatccgcgt tacaaagaaa gaagaaatcg cagccgcctt caaagaagca aagaaaaata
     2581 caaaagcacc tacagtaatc gaatttatca ttgacccaga agaaatggtc tacccgatga
     2641 tcaaaccggg cggaactctg gaagatatga tcatggattg ttaggcagga ggaaagatta
     2701 ttatggataa aggaatgaaa aaaagatgga tttctctcta tgttgagaac caggtaggtg
     2761 ttctgtccaa aatctccgga cttttctccg gaaaaagcta caatctggac agtcttactg
     2821 taggaactac cgaggacccc acagtatctc gaatgactat cgcaacagtc agcgatgatg
     2881 aaacctnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnngacagt cttactgtag
     3001 gaactaccga ggaccccaca gtatctcgaa tgactatcgc aacagtcagc gatgatgaaa
     3061 cctttgaaca gatcaaaaaa cagttaaacc gcatgatcga ggttatcaag gtaattgact
     3121 tcacagatgt atttgtcaga atgaaagaaa ttctctacat caaggttttc aactgctcca
     3181 gggaagataa agcagagctg tttcagattg cagaaacctt caaggcaaaa gtcattgact
     3241 atggcaaaga cagtctgctt ctggaatttg tccagacagc aaccaagaat gacgcagtag
     3301 tgaaactgat caaggaagaa tttcacagaa ttgaagtggt acgtggagga agtgtaggaa
     3361 tcgaatctat cagtatgatg gaacgataaa actttttctg aaatttttat aaagggagga
     3421 ttgtcgcatt gttcttaatg ctcagtcctc cctttactta cggttcttcc atcttttcgt
     3481 ttttcatctg tgctttcgct tttcgcccaa tccgtgcatt gctgttcata atactggcac
     3541 gggtgatctt atcatttcca aatttcatcc ggatctcatc catagctgca tccagctttc
     3601 tgtggcgttc tttattttct gtatcttcaa acagagacat ctgttcataa gtgccatctg
     3661 taaggcctgt cagtgccaca ccaatcagac gtagcggctg tcctttccag aattctttaa
     3721 aaagccttgt agcatttata taaatttcat ctgtaagatc tgtagcattt tccagctttg
     3781 tctggtgtga acggtttctg aaatccaaag tacggaaagt cacggaaata cagttgcatt
     3841 tcttatcttt tctgcgcatt ctggttgcca gaacatcaca ctgctccaaa agtatgggaa
     3901 acacctgctc tatggaagta atatcatcgt taaaagtagt ttccacgctg aaaccttttg
     3961 cctcatcagg cactgctttt acaggggaat catcgatacc tctggcatat tgccatagct
     4021 gatgtcccgt tttttcccca agccagtact gcacattgga tgctctttct cttgccagat
     4081 caccgatggt acggattcca tgattcagaa gcttctgctc ggaagctttt cccagaaaca
     4141 gcagattacg gataggaaga ggccacattt tctccgggat ttcatccggg aacagagtgt
     4201 gtactctgtc cggcttttga aaatctgatg ccatctttgc caaaagctta ttggtagaaa
     4261 ttcctacatt tactgtgaat cccagctctc tgtgaatctt gtctttcagc tcatgagcag
     4321 cagctacagg gtcaggatag atcagagaag tacctgtcat atccagaaat acctcatcaa
     4381 tggaaaaaga ttccatcaca ggtgcaaagg aagcacagat tgctttaaat gcccgggaac
     4441 atttatcgta taattcaaaa tcactgggaa cgatcaccaa attgggacat ttccgaagag
     4501 ccatagctac tggctcgccg gtctggatcc cgtatttttt tgcagggata gatttggcaa
     4561 ccacgatacc tgtccgtttc tttggatttc ctcctacaca ggaaggaatt tctctgagat
     4621 ccggcaaccc ctggctcacc cttctggctg attcccagga aagaaatgca ctgtttacat
     4681 caatatgaaa aattaaccgt tccgtacttt tcactgttct tcctccaata tatgaattgc
     4741 gctcttcata tctgatgatt tcattttacc ctgatctgct ctccagggta agaacctcgt
     4801 ttgtccaaaa aagtgtcttt atttgcatca tcttgtctga gctgttactg tatttatatt
     4861 tgtttgattt cactctgcta tcagagtttt gaacaacaac gccgcacttg ccatacggca
     4921 gtgcggcgtc tgtatttcgc taccggtcac attgttcccg gtaacttttt ttacttaatt
     4981 ctgaggattc atttcctctc gatatatact tatcgattag tcataaagat taggagcaat
     5041 ttcttcgctg tccatatttg tggaatcata ccagtatcca gttcagcctc cagccattca
     5101 taagagaatt ccgggaatgt ctgatgtttg aaatttttcc atgttactcc tttctcatga
     5161 agtaactgtc tacacataag caaacagtgc catcgctgtc attgatcagc aataagcccc
     5221 cgtgttttca tatagttcca ttataccttc tcattttccc gaagtcaaca taatttaaca
     5281 tgtatcagcc gtttatttgt gttgcttttt atttgatttt tgttgtattt cagttgtttt
     5341 tattttgttt cctcattgac atttaaatcc tcatctgtca tacttgaata taacgaatgt
     5401 accatcaaac agcagctttg catcttccgt aaggctctta tcatatatag aaaccgctct
     5461 ggaaaggaga caaacaatgt atctttctga catccacaca cattctatcg ccagcggtca
     5521 cggaaccacc tgtaccatct ctgacatggc aaaagcagcc agcaaaaaag gactgaaact
     5581 ccttgggatt tctgaccacg gcccgggaac tctggcttcc ggaacttctt cttatttcag
     5641 aagccttcct ttttatccca gaaaaagatt cggcatagat attctttacg gagttgaact
     5701 aaacatcctg gacagtgcag gacatacaga tctgtcagat gaactgctga acaacctgga
     5761 ttacgctatc atcagtatgc atcggcagaa ctaccgttca ggctctgtat ctcagaatac
     5821 agaagcttac atcaatgcaa taaaacatcc tgctgtaaaa atactcggcc actgcgacga
     5881 tacacatttc cctgtagatt atgaaacgct ggcaagagca gctttacggg aaaatgttat
     5941 ttttgaaata aacgaagctt ccctcgcacc cggaggatat cggggagaca caagagccaa
     6001 tgcagccaga atcctgtatc tctgtcagaa atatcagctt cctgttattt tgtccagcga
     6061 cagccacgga aaagaacatg ttggagattt cacctatgcc gaagaattcg ttcaccagct
     6121 catgtttccg gaaactctta tccttaacaa ccagcttccc aaattaaaag ttttccttca
     6181 gacacgttaa aagaatgttc ctcaaaggga cattctttta ttttatgcat tgttttttgc
     6241 attgtgttat tttgtttatt ttctataatt tcttatcaaa aaagatgaca ttttagtaca
     6301 ttttaactag caaaactcac ttaaccattt acatatctcg tgatagatca gtcttactgt
     6361 aggaactacc gaggacccca cagtatctcg aatgactatc gcaacagtca gcgatgatga
     6421 aacctttgaa cagatcaaaa aacagttaaa ccgcatgatc gaggttatca aggtaatcga
     6481 cttcacagat gtatttgtca gaatgaaaga aattctctat atcaaggttt tcaactgctc
     6541 cagggaagat aaagcagaac tgtttcagat tgcagaaacc ttcaaggcaa aagtcattga
     6601 ctatggcaaa gacagtctgc ttctggaatt tgtccagaca gccaccaaga atgatgcagt
     6661 tgttaaactg atcaaggaag aattccacag aattgaagtg gttcgcggtg gaagcgttgg
     6721 aattgaatcc atcagcatga tggaacgcta aatctcataa tcaatatttt ttgcaggata
     6781 tagaaacacc tctatatcct gtatttattt tcaaacatac tataaaatat tgcagttttt
     6841 aatcaaatgt gttattgttt acgggagcgt tattcgaaag aaaatgcatc tgatttccac
     6901 atctgacagt ctggtggata aagtcatcca cttcacagtc tggttaaatt tgtgaggcga
     6961 cctgtaaggc gtctacacac cggaaacttt taccggaaga tatttcttgt ttcatatctt
     7021 ttgttctgat gtatattttt cataacgcct gatccccata ctctaaactg tctgaaaagc
     7081 aggggacgca ttgcgccgtt ttatcagacc aaaaggagaa ttcatatgaa cacaacaaca
     7141 actactacaa cagctgccac aaaaagaagc agcactcttt acatggtaga gctggctatg
     7201 atgattgcca ttattctgct catgtccttt accccgctgg gctaccttcg tactcccggc
     7261 ttatccatca ctcttctcac catcccggta gctgtaggag ctatcatcct cggaccgaaa
     7321 ggtggtgctg tatgcggact tgctttcggt gcaaccagct tctatatggc tgtcacagga
     7381 agttcagctt tcgctgccgc actttttaac attaatccat ttggcacttt tattgtgtgt
     7441 atcgtggcac gtgtgctgga aggatggatc acaggactta ttttcgcagc attatataaa
     7501 tcaccggcga agaaattttc ctattacgtt gcttcactgg catgcccgtt actgaatact
     7561 ttcttcttca tgggcttttt atgtctcttc ttctacaaca cagattacat tcagggtatt
     7621 gtttccagtc ttggagtaag caatcctgtt gtcttcgttg ctgcttttgt gggcgttcag
     7681 ggactgatcg aagcgggctt ctgctttgta gtgggaagca tcgtttccaa ggcactttct
     7741 gtggcactga aacgtgcata atctttaaaa gaacagccgt ttaccaaaca accctgacta
     7801 cattgtcact gtagtcagga tttttttatc cggcacattt aaagcaggaa ccctacctga
     7861 ttcggttaat acaaaggaga tttttatgtc attattaaaa gagatttcta ttacagatct
     7921 ttcaaattta cgcatcggtc atgcttccga ttataatgcc cagaccgggg taaccgttct
     7981 ttacttccca ctgggtgcaa aggttggctg tgatatcagc ggtggcggtc ctgcttccag
     8041 ggaaactcct ctcacctctc ctgtcactgc cgacaatccc atcaatgcta ttgtcttgtc
     8101 cggaggttct gcctatggac tggctgctgc tgacggtgtg atgaactatc tggaatcaca
     8161 aaatatcggt tataacaccg gtgcagccct ggttcctctt gtatgccagt cctgtatcta
     8221 tgacctctct tacggagatc ctaaaatacg tccaactgca aaaatgggcg aagaagcctg
     8281 ccgtcaggca tttgcaggaa cagataccag aaccggaaat atcggtgcag gtaccggtgc
     8341 aactgtggga aaactttacg gtatgaaaca atccatgaag tcaggtcttg gtattgccgc
     8401 tgtatctgtg aaaaatttcc agatggccgc aattgtcgtt gtcaatgcac tgggagatat
     8461 cttcagtcca caaaatggtc agaaaattgc agggctgaaa acacctgaca gaagcgggtt
     8521 tctggacagt gtccacgaat tataccgctt tatgacacct catgaccagt ttaccggcaa
     8581 taccaccatc ggagctgtaa tcaccaatgg ggcattttca aaggctgaac tgaataaaat
     8641 tgcctctatg acccgctgtg cctatgccag atgcatcaat cctgtagcaa ctatggctga
     8701 cggtgattcc atctatgctg ccagcattgg caatgtttct gtggatatca acatggctgg
     8761 aactctcgcc gcagaagtca tggctcaggc tatccaaaat gccatccata cttcccggat
     8821 ccaggatgaa gaatttctga aatatgtata acagtccgct ataaaagcgc agagaaaaag
     8881 tatcatctct gcgcttttat tcttcctgtc tgtcttcatt tttcatctgt gctctggttt
     8941 ttctccaagc cagagctgta catttgcttc ccgttccctt gccagatcac caatagtacg
     9001 gattccctga ttcagaagct tctgctcgga ggcttttccc agaaataaca ggttacggac
     9061 aggaagtggc cacattttct ccggtatttc gtccgggaac agcgtgtgta ctctgtccgt
     9121 ttctttggat ttcctcccac acaggaggga atctccctga gatccggcag cccctggctt
     9181 acccttctgg ctgactccca ggaaagaaat gcgctgttta catcaatatg aaaaattaat
     9241 cgttccatac ttttcaatat atctcaatca tatttttgca gacttccaat catcttaatc
     9301 cccattatca tcaacacagg aaaaatcagt gccgcaaaga ttccaagttt cagattatca
     9361 ttcagtgctc ctgaaatcat ccccacatag gttggtccgg atgagcatcc cacatctcca
     9421 gcaagggcaa ggagggcaaa caaggctgtt ccgccacgct ttactgaggc agccgccatg
     9481 ctgaaggttc ccggccacat aatacctaca gacagaccgc aaaccgcaca tccaaggatt
     9541 cccaacgcag gtaccgggat aaatgcgatc atcagatagg aaaccatgca cagaactgca
     9601 ctgtattgca taaagcgttc cagattgatt ttatctccaa atttcccata aaatgccctt
     9661 gaacttccca taagaattgc aaacgccatg ggacctgcca gatctccgat agttttattg
     9721 attccaaagc ttttctcagc cagagtagaa gcccactggc ttaccgcctg ctcactggct
     9781 cctgcacaga gcatcattaa catcagaacc cagaagattt ttttcttaaa aagctctccc
     9841 atagtcagcc ccttttcacc ctcatccagc agtggagcaa tgggaactct ggtaaaaaag
     9901 attccatttg caatgggaat caatgcccac accagcgcca tatatttcca gtttgcaatc
     9961 ccgaaaatac gaaagaataa tgtagaaaga agtaccactc ccacatgtcc ccaacagtaa
    10021 aaggaatgaa ggagactcat tgctttttcc ttattatctg tagggcaggc ttccaccaca
    10081 ggacttacca gcacctccag caatccgcct ccgatggcat agatcataac tgcaatgaga
    10141 agtcccacaa acggatctcc caggcactcc ggcaatactg tgagcaaaat cagacctgca
    10201 gccgccattg catgtgccag gatcatagat gcacgataac ctattctgtc cacaaatcca
    10261 atcgatgcca gatctaccag caactggatc ccgaaattaa aagtaaccag aagtgtgatc
    10321 ttctgcagcg aaatcccgta actgccctga aatgtcagaa acagcagagg aacaaaattg
    10381 tttacaatag cctgcaccac atatccgata aaacaggcct gcactgttct gttgtaattt
    10441 gttttcattc aatatgatat cctccaatct gaaatttatt agttactgag aacggagtaa
    10501 gcagtaacaa tttattacgc tgatatcgtt caggcattct cattcaccaa attctgcacc
    10561 ttcacagttc tatcaatcaa taatgacagt gtatcacaga ttctttcttt tttctttcat
    10621 tatattttga aaatcctata aatttttatg ttattttgac tttttctcat ataacaattc
    10681 tatacactct aacaggtaat ccatcaatcc aattcaaaat atttcccgca aaaaaagatg
    10741 tgtaccatac catttctgac accatacaca tctcaaaata aacacttctt atcttctgta
    10801 ctccgcagtc aggtctttaa taacctctcc tgcaataatc agcccgacga cagacggcac
    10861 aaaggccaca ctccccggaa tatctctgcg ctccgtacac ttatgcgtag cacctggagg
    10921 acaaatacaa tgcgacctgc agctgatcgc catatcttca attggtctga tcggctgttc
    10981 ctctgaataa acaaccttca gtttcttcac accacgcttc ttcagctctc tacgcataac
    11041 cttcgccagc ggacacacct tcgtcttata gatatccgcc acccgaaacg cactggcatc
    11101 cagcttattt ccggcaccca tactgctgat aacaggagtc cctgcctcct ttgcacgcat
    11161 gatcagttca atcttcgcag tcactgtgtc cacagcatct accacataat catactcact
    11221 aaaatcgaaa tcagcagcat tctccggaag ataaaaacag ttatggattc tcacatctgc
    11281 tttcggatta atgtccagga tcctgtcccg catcacctct gttttatatt gaccaacagt
    11341 tttcctggtg gcaataatct gtctgttaag attcgtcagg catactttgt catcatcgat
    11401 cagatcaaag gtccccacac cgcttctgac caatgcttca catacatatc ctccaacccc
    11461 tccgattcca aacactgcca cgcgggagtt ctccagttta ttcattgctt cttttcccaa
    11521 aagaagctct gttcttgaaa attgattcaa cataatatct ccatttcatt cggtattgac
    11581 cgactatctg cctgcctttc ttctacttca ttatttctgg tctgttctgc tttgctgcct
    11641 gtaatgtaag cagctctgca tgccagaaac aaaaaaacaa ggagcagaaa ccaaagccag
    11701 agctttcttt tgttttttat gagcaaccgt ttcataatct gcatcactat tccttaatat
    11761 attattttca gataccagag ttgcaacata cttccatcac agatttctta tgatatcttt
    11821 acttctataa tgcgtcaagt atatcataga aagaaaaatc ctgcaatgaa gaaactctgt
    11881 tactgtacat gaagtgaaca gtgctgagtg aaattcacaa accggaagtg cttatccatc
    11941 tcatcaccaa tcaatccaat tacttttccc atggtaaatg ccgccatcac tgttccgatt
    12001 cccagtccgt tgatatgccc cagaatcagc cctgtcatac aggcagtaat catcagacag
    12061 atcacatcaa aagaaacctt gatcttagaa tatttcacct ttataatctc tgacagttca
    12121 cgaggaaaca gatctgtagg aataatcggc agaccgcatc tgttagaaag tgcgatccct
    12181 atacagatca gcagataact gatcacaaaa tataacactc t
//
