LOCUS       gnlProkkaKOFLAKMA_83    4888 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KOFLAKMA_83.
ACCESSION   gnlProkkaKOFLAKMA_83
VERSION     gnlProkkaKOFLAKMA_83
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 14:25:26
            Original ID  :: gnl|Prokka|KOFLAKMA_83
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4888
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1257
                     /locus_tag="ctg83_1"
                     /transl_table=11
                     /translation="MIIGLIAGIIYDIFFVKKKEMVLRRILYIGMIFWLTAQYWAGYQS
                     LLMIILGSGIIVLYVFCYFDCTFKQAYVWNFFYAVNIGLIKEAYVVYAGVFNHKQWDDF
                     YSYPRGHTYQEVIFWILGCLFIFWIIKFILSVNSIKGILRTRLKELFIIGLLEYVLLIV
                     SIIYKFGTIKKENFVMTACLLAVSNIALIGVYVKFQKKTLEMRNQILDMRCKLMEEEYE
                     ELRMSYDRYRCLVHDEKHLLLYIKECLENGELDSCITFLNHYKRESIRYSGVAWTGIPE
                     INFMLNIKVRKMEEKNIFFKVDSKIEKIPMKDIDFVVLLGNLLDNAIEAAEKCEEGKGK
                     ITCIFRNINDMFIFKVKNTSIYKPYEKNTKFYTSKKEKDEHGWGIESVKQIVRKYNGEI
                     DFKYDKDFFEVEIIISDNT"
     protocluster    1..4888
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1434:4086]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1435..4086
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..4888
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4888
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             1274..1402
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg83_2"
                     /transl_table=11
                     /translation="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYGTIVCC"
     CDS_motif       1274..1384
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /locus_tag="ctg83_2_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       1385..1402
                     /prepeptide="core"
                     /locus_tag="ctg83_2_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="519.7"
                     /monoisotopic_mass="519.2"
                     /core_sequence="TIVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /leader_location="[1273:1384](+)"
     CDS             1435..4086
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     762.1; E-value: 1.5e-230)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg83_3"
                     /sec_met_domain="DUF4135 (E-value: 2.1e-94, bitscore:
                     304.8, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.6e-53, bitscore:
                     168.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLKILILDVHRQKNFGNLKGSTPKEQYDYYEKKYLNNATYVKSL
                     LQEYPELKRLLELKNNSIQRAECEIRKSLYAEKEQIQKIFCDGRKFSGTVGIYMSKGDI
                     HRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGISCRTVQYLSHDSYGW
                     EEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAHGEYPVIIDMETYPG
                     YLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNRGVLISAMGTEEKIK
                     TPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYTECIIRGFCRAYMVA
                     MADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSRECRKALLNVIHKEGE
                     SSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLPCTPYESWRMHMKQM
                     SYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIYSQIRKIVHRICSRA
                     IIREQSAGWAGLQFWDNGHWNLRSGGIYLYDGISGIVLFLAKYLHDFEEKNASAEEIYH
                     LAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLTGKRVWMIYAEKHFS
                     IIERVWKEDSQLDYLSGNAGAIVVAVMLYKETGNLKYYEIAADMEKDLWKKGQETGNGY
                     GWRLKGTDGPLAGMSHGNSGFLMAYAALYECNHKAEYADKIQLLLRYEDSLYSEKAGNW
                     KDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLNAADSLFYGEQDEKI
                     CLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAKISGTEYLNLAFMNG
                     ISGTGMALMEIL"
     CDS             complement(4139..4663)
                     /locus_tag="ctg83_4"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIARKLKLSRQYVNRMKK
                     KLILRYISENK"
ORIGIN
        1 tacataattg gattaattgc aggaattata tatgatattt tttttgtaaa gaaaaaggag
       61 atggtcttaa gaagaatatt atatatcggc atgatatttt ggttaactgc tcagtattgg
      121 gctggatatc aatcgttgtt aatgattatt cttgggagtg gaataattgt attatatgtt
      181 ttttgctact ttgattgcac atttaaacag gcatatgttt ggaatttttt ctatgcagtt
      241 aatataggat tgataaaaga ggcttatgtt gtatatgcag gggtgtttaa ccataaacag
      301 tgggatgatt tttattcata tccgagagga catacatatc aggaagttat attttggatt
      361 ttaggctgtt tattcatatt ttggataatt aaatttattt tgtcagtaaa cagtataaaa
      421 ggaatattgc gtacacgtct gaaggaactt tttattattg gattgttaga gtatgtttta
      481 ttaatagtta gcatcatata caaatttggt acgattaaaa aggaaaattt tgtaatgacc
      541 gcatgtttat tagcagttag taatatagca ttgattggtg tatatgttaa gtttcaaaaa
      601 aagaccctag aaatgagaaa tcagatttta gatatgagat gcaaattaat ggaagaagaa
      661 tatgaagaat tgagaatgtc atatgaccgg tatcggtgtt tggtgcacga tgaaaaacat
      721 ttgcttttat atataaaaga atgcctggaa aatggagaac tggattcatg tatcactttt
      781 ttgaatcatt acaagagaga aagcattaga tatagtggag tagcgtggac aggaattcca
      841 gaaataaatt ttatgttgaa tataaaagtg cgaaaaatgg aagaaaagaa tatttttttt
      901 aaagtagatt caaaaataga aaaaattccg atgaaagaca tagattttgt tgtactccta
      961 ggaaatcttt tggataatgc aatagaagct gctgaaaagt gtgaagaggg aaaaggtaaa
     1021 attacgtgta tttttcgaaa tattaatgat atgtttattt ttaaagtaaa gaatacaagc
     1081 atatataaac cttatgaaaa aaacactaaa ttttatacaa gtaaaaaaga gaaagatgag
     1141 cacggatggg ggattgaaag tgtcaaacaa attgtaagaa agtataatgg tgaaatagat
     1201 tttaaatatg ataaagattt ttttgaagta gaaataataa ttagcgataa tacataatgg
     1261 gagagtgacg gttatgaacg aaatgaatga taaaataata ggaaatgtgg aaaaagaatt
     1321 agatgaaata gagataatag atacggaaag tatagaagag aaattgtctt ttattgtata
     1381 tggaactata gtgtgttgct gaaattggat tatttatgca gaaaaaatcg aactatgttt
     1441 cttaaaatat taatcttaga tgtacatcgg cagaaaaatt ttggaaatct aaaaggaagt
     1501 acgccaaaag aacaatatga ttattatgaa aaaaaatatc ttaacaatgc aacatatgta
     1561 aaatctttac tgcaggaata tcccgagtta aaacgtctgc ttgaattgaa aaataactct
     1621 atccagagag cagaatgtga aatcaggaaa tctctttatg cagaaaaaga acagatacaa
     1681 aaaatattct gtgatggaag aaagttttcc gggactgtgg gaatttacat gtcgaaaggc
     1741 gatatacaca gaggaggacg aagtgtggcg aaggtagaat tggataatgg aacaattctg
     1801 tactataagc cacatagtct tgataagaat ataaaatatc aggaacttta taactattta
     1861 tgcagaaaaa caggaatttc ctgcaggacg gtacaatatt tatctcatga ttcctatgga
     1921 tgggaagaaa aaattgagaa tattccctgt aaaaacgaaa gtgaggtgga gcattattat
     1981 ttcagaatgg gcatacatct gtttttggga tatgccctcg gagcaacaga tcttcatggt
     2041 gaaaatatta ttgcacatgg agaatatcct gtgattatcg atatggagac atatccggga
     2101 tatttaaaac aacaatcaga gaaagacgga agtagtgtag aagaaaaaat aaacaaaagt
     2161 acagagataa aattggcaaa ttcggttata catacaggaa tgcttcctgt tctcacatgg
     2221 ggcagaggaa acagaggagt tcttataagt gcaatgggaa cagaggaaaa gataaaaaca
     2281 ccgtttaaac ttcctgtggt aaaggatgat aaaacatctg atatccacat agaatatgaa
     2341 cctgtggaaa tgcagataaa ggaatgcatt gtaagactaa atgatcaggt tatcaatgcg
     2401 gcagattata cggaatgcat tatcagagga ttttgcagag cgtacatggt ggcaatggca
     2461 gataagaaag tggaggtgat gttgtccggc ttttttgacg gacgttccag agttgtactg
     2521 cggcataccc aacagtatgc aatgtatctt atggcttcgt ttcatccgga ttatatgaag
     2581 tcaagagaat gcaggaaagc tcttttgaat gtgattcaca aagaggggga atcttctttt
     2641 atgaaagaga ttcatgatta tgaaattgac agccttctgg aaatggatat accctgcttt
     2701 gagattgatg cgaacagcag atctgtttat gatggaaatg gcggagaaca taaagaatat
     2761 ctgccctgta ctccttatga gtcatggcga atgcatatga agcagatgag ttactctgat
     2821 atggaatgtc agtgtgatta tatcaggctg tccatggaaa tgctgaaggc atctgatgga
     2881 aagaaaaaga tgtttccgac caggataaag ggatatgaca cagataaaga gcgcaaaata
     2941 tacagtcaga tcagaaagat agttcatcga atctgcagca gagcaattat ccgggaacag
     3001 agcgccggct gggcgggtct gcaattctgg gataatggtc actggaatct cagatcaggt
     3061 ggaatatatt tatatgatgg aatatccggg atagtcttgt ttcttgcaaa atatcttcat
     3121 gattttgaag aaaagaatgc aagtgcagaa gaaatttatc atcttgctgt tttgagattg
     3181 aaagcttata cagatgaaat acacaaaaaa cagatttatg ataaaaatct tctgacaggt
     3241 attgtaaatg gagaaagctc ggtggtatat acctatcttt atctgtttaa acttacagga
     3301 aaaagagtgt ggatgattta tgcggaaaag catttcagca ttattgagag ggtatggaaa
     3361 gaagattcac aactggatta tctgagcgga aatgccggag ctattgtagt ggcagtgatg
     3421 ttatataaag aaaccggaaa tctgaaatat tatgaaatag cggcagatat ggaaaaagat
     3481 ttgtggaaga aaggacagga aaccggaaat ggatacggat ggagattaaa aggaacagac
     3541 ggaccgctgg ctggaatgtc tcatggcaac agtggatttc tgatggctta tgcagcgttg
     3601 tatgaatgta atcataaagc ggaatatgct gataaaatac agcttttgct gagatatgag
     3661 gattctctgt actcagagaa agccggaaac tggaaggatt tacgagagag ttcaggggaa
     3721 agcttcatga atgcatggtg ccatggggcg ccgggaatcc tgctttcacg aatgaaactg
     3781 gaagagctgt ttcctgagga tatgcagatt aaaaaagaca ggttaaatgc tgcagactct
     3841 ttgttttatg gagaacagga tgaaaaaatt tgtctgtgtc atgggatgtc cgggaattta
     3901 cttattatga agaagtacct tcgaaaatat ggtaataaaa aaatgaagga gcaatatgag
     3961 gcgttatgtg actgcctttt atttcaactg gatcacccgg caaaaatatc tgggacagaa
     4021 tatctgaatc tggcttttat gaatggcatt tccggtacgg gaatggcatt aatggaaatt
     4081 ttatgaaaac taagggaaca cctgcagact gtaaatttat ggtcagcagg tgtttctttt
     4141 atttgttttc ggaaatatat ctgagaatta gtttcttctt catccgattg acgtactggc
     4201 gggacagctt cagtttccgg gcaatctggg catcgctttt atcctgataa aagtacatgg
     4261 acagaatttt tctctggaca ctgtccgaag ggtaagagtt gatatatgcg gttacatcat
     4321 aataggtgtc atcaaaactg tcgggagcct gtaatgaaac agaacaagaa tcaaaatcat
     4381 ctttttcagg ttcggaaaga caactgcggc aaagggaacg atatctgttt tcgacagagg
     4441 tctgcatgta tctgatacat tcaccttctg aggatgaaga acttaaatat ggcaatgtct
     4501 ttaacaaagt aagatacaat tcctgtgtgg aatcttcgcg ttccatgcag tgaatccggg
     4561 atgcatatcc tttcacaagc ggttccatac gtttgagaat ttcactgtct gaatctggga
     4621 taccattttg ataattttgg ataagttctg tcagtgtttt cataggtatc tacctccttt
     4681 ttaggggaag tagtaagaaa actgctgatc agaaactaaa aaagaaaaaa atttgtgagt
     4741 ttacaaatgg aagagaaaaa actctttatt aagtgaggtt gcaaatttag atcagcgata
     4801 ggagaagaaa tacatggtaa aaagagattt gcaaaataat tgtagagaat agaaatatgc
     4861 tttaaattaa aacggtaata ataagatt
//
