LOCUS       c00115_gnlPro..        13378 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CIFKKMLO_115.
ACCESSION   c00115_gnlPro..
VERSION     c00115_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 12:32:46
            Original ID  :: gnl|Prokka|CIFKKMLO_115
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13378
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..219
                     /locus_tag="ctg115_1"
                     /transl_table=11
                     /translation="LCTFQTGKRYNCDLSASYNIGARYFIRELLKPLPATERSLLEAKV
                     PPVKRRTSCVYADLRELHLQMEILKVA"
     protocluster    1..13378
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5332:7584]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5333..7584
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13378
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13378
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             909..1346
                     /locus_tag="ctg115_2"
                     /transl_table=11
                     /translation="VATKVDKKNAIRQGITEAEIVYFQNLAGKTFLYVCGDEYFEVSFP
                     IDHFLHLTGVETRLSTKDFYKNAKKSILTNNQFYFDARHVYANAKRKLPCLKRLPELTN
                     EMVCVLKNMETMTITYKLSVTNLEFTGSVTRKPKRYTGKKD"
     CDS             1478..1837
                     /locus_tag="ctg115_3"
                     /transl_table=11
                     /translation="MPKTSYICNCDVIHEDIVNDVKSKMQPKDDYIQLASLFKLFGDGT
                     RVQILHALEQSEMCVCDLAVLLGVTKSAISHQLKALRLANLVKFRKEAQIVYYSLADDH
                     VKEIIDKGFEHLWQK"
     CDS             1897..4251
                     /locus_tag="ctg115_4"
                     /transl_table=11
                     /translation="MKRIFLLKGLDCPNCSAKIEKEVGELDGVQSSVVNLMKQTITVNV
                     TQTAADTIASQIETIVYSHEPDVEVQEETVMNVTKSYSLKGLDCPNCSAKIEKEVGELD
                     GVQSSVVNLMKQTLTINVAQTAADTIASQIETIVHSHEPDVEVSEIVQESYIPEKKQEA
                     NESYNNEDKKLTVRLATGAAIYAIGMALTVFAKVPLPIELAFLIVSYVILGGDVVWQAV
                     RNISKGRVFDEHFLMSVSTIGAFVIGEYPEAVAVMLFYQVGEFFQSLAVKRSRKSISDL
                     MDIRPDSATVRRNGELITISPENVSIGEIIIVKPGEKIPLDGVVLDGDSMLDTRALTGE
                     SVPRSVHKGDEALSGCMNQTGVLMIKTTKAFGESTASKIIDLVENASSRKAPTENFITT
                     FARYYTPVVVILAAFLAILPPIILGGGWTEWIRRGFVFLVVSCPCALVISIPLTFFGGI
                     GAASKRGVLVKGSNYLEALNNVSVIVFDKTGTLTKGVFNVTDILPANGFSKEQVLEYAA
                     EAESFSNHPIAKSILAAYEKEIDQSVISDYKEISGYGISVMAGEKKVFAGNTKLMDTEC
                     IEYTTCEKAGTKVYLAVDGQYAGCILITDEVKPDSKKAISDLKHIGVEKTVMLTGDDEK
                     IGKSVAEELQLDKYYAQLLPDQKVEKVELLDSKKRPGSKLAFVGDGINDAPVLARADVG
                     IAMGGLGSDAAIEAADVVLMTDEPSKLVDAIEVAKATKQIVMQNIVIALGIKSVFLILG
                     ALGIAGMWEAVFGDVGVTIIAVLNAMRILKK"
     CDS             4268..4786
                     /locus_tag="ctg115_5"
                     /transl_table=11
                     /translation="VKRKLILLVVTIVFLVGFGVILHSPPSMIDAVTGATPKSKKAAQA
                     SAQLEGSYVLGINMMSDGLDNENTRNKLKELALDDSETNETDLMKTDISFRLYVSETDY
                     PLVSYAKKLCDRLKQAGFSVDLKEYSNTMMLSRVVSGKYDVFLASDDFIDVTTLTQMDY
                     MIMDSEEMR"
     CDS             4797..5336
                     /locus_tag="ctg115_6"
                     /transl_table=11
                     /translation="MRKWNTILSVLMLLIFMIHGIMGSFMLNGVGSSAGKLLAWIGVGI
                     LVVHTVIGVILTVQSLQTAKQSGKMYLKQNAIFWARRASGMAILILLLFHIGLFGKVQN
                     GTYILFPFTTVKMVTQLLFVAAIFVHIFINIRPLLVSLGIISYKERRSDIYLILSVLLL
                     FIAGAVILYYIGWQYL"
     CDS             5333..6877
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 270.5; E-value:
                     9.3e-83)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg115_7"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.4e-83, bitscore:
                     270.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.5e-17,
                     bitscore: 52.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTIIIIGAGLAGLSAALQAAENGCNVKLVSSLPSERAQSVMAE
                     GGINAALNTKDENDSPEEHFTDTIKAACGLADPNAVWGMTQAAPELVHWLLKLGVKFNM
                     SGYDDVDLRNFGGQKKKRTAFAQSDTGKQIMTAMIDAVRRKEASGMVERFSHHSFLTLR
                     LCGNICCGCVIRDEYSQETVELPGDAVIVATGGMHGLFGNTTGSLSNTGEVTAELFRLG
                     VPLANSEMIQYHPTTVKCGGKRMLISEAARGEGGRLFAMKDGKQWYFMEEKYPELGNLM
                     PRDITAREIWKVSHESEVFLDMTEISEEIISNKLSGLADDCMTYLHKDIRKEPVSVLPG
                     IHYFMGGILVDEQHRTPIQNLYAAGECCAQYHGANRLGGNSLLGALYGGRVAAKSACEQ
                     ADVVDLSCATQIDFPPASQISEIKQLNKVMQDTMGVVRNENTLLNGIQTVQALTGNLPL
                     LGMAVLKSALARKESRGAHWREDYPKSNDDDYLKTTVARFDGKQIQISFVPVPERR"
     CDS             6883..7584
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 91.5; E-value: 1.1e-28)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg115_8"
                     /sec_met_domain="Fer2_3 (E-value: 2.9e-29, bitscore: 91.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00067, bitscore: 10.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVYKIRIRRQESQKSDSYWQEFEFDGSKNSSVANVLKELNSRTPL
                     KDNSGNIVTPISWECSCMVRKCGACAMLINERPRLACSTFLHTLKGSTITLEPLSKFPL
                     VRDLIVDRSILFENLKKLNLWLESEAYMNPWTHEPRYQSARCLMCGCCLEVCPNFSANG
                     TFAGAVAAVNAFRILNEEQESTHLNEISAEYKKKYFEGCGKSLSCHDICPIGLPVEELL
                     VRSNAAAVWGK"
     CDS             7609..8352
                     /locus_tag="ctg115_9"
                     /transl_table=11
                     /translation="MYEENQKLKTWITPDLATEYLAGAVLLGAAPCTAMVFVWSTLTKG
                     NPAYTVVQVASNDIIILFAFVPIVKFLLGVSNVSVPFQTLFMSVVLFVVIPLAAGIITR
                     LLVVRKKGTEYFEQTFLHKFDSATTVGLLLTLILIFMFQGEVVLDNPLHIILIAVPLII
                     QTFFIFFLAFGVCRIIRLPYDIAAPAGMIGASNFFELAVAVAVALFGTSSPAALATTVG
                     VLTEVPVMLTLVKIANKLKEKFKYE"
     CDS             8345..8758
                     /locus_tag="ctg115_10"
                     /transl_table=11
                     /translation="MNKKKVAFICVHNSCRSQIAEALGKHLASDVFESYSAGTETKLQI
                     NQDAVRIMKELYGIDMEAEGQYSKLIDEIPVPDIAISMGCNVGCPFIERPFDDNWGLED
                     PTGKSDEEFKKVIDEIRMQIFILKQRLDEFEEN"
     CDS             9464..9913
                     /locus_tag="ctg115_11"
                     /transl_table=11
                     /translation="MLQYFQFPKFLLKLRISQTAKFLYMILYDRARISRKNSWIDKYGN
                     VYLIFPIDELSVQIDKCKSSVKTALKELDDVGLLVRRSGGFSKPNHLYVKIPSDEIGLQ
                     PVDNKAVEKIVATEPEKPPSSGRKNGCGGVGNVAPSTTNIKLLIV"
     CDS             complement(9910..10629)
                     /locus_tag="ctg115_12"
                     /transl_table=11
                     /translation="MEIKPFKIKYYLERKDPDFENKMHDVLLVYKQVEMQFDDNGNIII
                     PDNGHLTHTISYDEKPGIQAVANKYPDYNPTEENGYIRRDYEYVRLGTLSLLAGIDLLT
                     GEAIPLVSQTHKSSDFIKFLKMLNAKYPEGDTIRLILDNHSAHTSKETRQFLAVLPEDR
                     FVFVFTPTHTSWLNMIESFFSKMTKQMLKGIRVNSKEELSERIYRYFDEINADPIVYHW
                     TYKYKMDEIDPDEVATI"
     CDS             complement(10645..11079)
                     /locus_tag="ctg115_13"
                     /transl_table=11
                     /translation="MPALPYSITISDEERAYLKSLIKTRTIQAQVVDRARMLLWKSEAK
                     TDKAIADGLGVSVNTVRRCIDRYLNNGINLAIFDDERSGRPAEITDDAKSWIVSIACQK
                     PCDLGYAAELWTLAALHKHIQAHAEEAGYPRLKTVTKPWL"
     CDS             complement(11153..11461)
                     /locus_tag="ctg115_14"
                     /transl_table=11
                     /translation="MRMNQDEIRFDFHGLGLAIKQAREERGWTQAYVAELVGKTDRTIM
                     NIENKGQHPSFNLFFKLVTMFDISVDQFFYREEQRDEHSCRKHIDVLLNSMNEKELV"
     CDS             11653..12336
                     /locus_tag="ctg115_15"
                     /transl_table=11
                     /translation="MNYTILIVDDDMAINDMLVKYLRKNGYITYSAYSGTEALLFLEKQ
                     KVNLIILDLMLPGLSGEQVLVEIKKTKNVPVIGLSAKEDSKSKIFLLKNGADDYVTKPF
                     DIEELLARIETILRRIYENQYTSNSLLCCGDLNLDTIGMEATLKNQKLPLTKNEFAILK
                     MLMEHPQQVFTKDMIYEQLWNETLEGTENAINVHISNLRKKIAAIDNSKSYIKTVWGIG
                     FKMDI"
     CDS             12416..13336
                     /locus_tag="ctg115_16"
                     /transl_table=11
                     /translation="MEYILRTNTVSKKYTNYYAVDKVSISIKKGEIYGLIGENGAGKST
                     LMKMIAGLVEPSEGSIELFGNFVPQTERYRIGCVIESPALYAELTAKQNLEVFRKAYGL
                     SSKESVQQILKQVGLSQYENKIVKKFSLGMKQRLAIGVALLGNPDFLILDEPINGLDPT
                     GIQDMRNFLLKLNREEHITIMISSHILGELSKIATKYGIIKNGKLIEEITAKELNEKCQ
                     CCLKIKASDTAQAAILIEKNLHTKNYEILSDNNIRIFEYVDNPGIVNSLLVNHGISVDE
                     CTVTKESLEDYFNEIGNCETRGARS"
ORIGIN
        1 ctctgtactt tccagacagg aaaacgatat aattgtgacc tgtcagcatc ctataatata
       61 ggggcgagat attttataag ggaactttta aaaccccttc cggcaacgga aaggtcttta
      121 ctggaggcaa aagtccctcc tgtaaagcgt agaacctcat gtgtttatgc tgacttaaga
      181 gaacttcatc tgcaaatgga gatcttaaaa gtagcataaa cacaggcaga tatacagcgg
      241 attacctgta atgtgggaac ctgccgtatc cggcatggaa aaagcacata actgtgcaga
      301 cctaagttac aggcgtatcc gccgatattc agtctgacgc ctaaagcgtc tggaagcacg
      361 tgactttagc catgtgaggt tcacgattat cggaaaatgc ctgtaaacag cgtaaataca
      421 gcatttcaag gagttttaag caatgataag agtgttattt gtctgccacg gcaatgttta
      481 atggatgccg tgaaagcctt gattttattg gatttcttgg gaattaacca ataatttaca
      541 ccttatttat acctttggaa gaccggatcg gaataatata ataaaatttg ctaatctgtg
      601 ttgatttttt ttatgattga gtataataaa atcaagaaca gaaatgttct cgatgtaaga
      661 gcatcgttaa aagttgggct gcagatggag cagggtaaac ttccatctca ttagatgtct
      721 taactgggca tcgagcctgg tagcttggat aaagctgtag tccacgtggg ggacttaatg
      781 attttcacgt cgttatgggt atcttaactg ggtatcgagg ctgacaacca gcagaaaact
      841 cttttacaaa agtaattctc agaaaagtgt ggtttaatgc cacactcttt tttgcatgtg
      901 aggtataagt ggcaacaaag gtagataaga aaaacgcaat acgacaaggt attacagagg
      961 cggaaatcgt atatttccaa aatttggcag gtaaaacatt tctgtatgtt tgtggagatg
     1021 aatattttga agtttctttt ccaatagatc actttctaca tttaacagga gtggagacaa
     1081 gactttcgac caaggatttt tataagaatg caaaaaaatc tattcttaca aataatcagt
     1141 tctattttga cgcaagacat gtatatgcaa atgccaaaag gaaacttccg tgtttaaaac
     1201 gcttgccgga attaacgaat gaaatggtat gtgttctaaa aaatatggaa accatgacaa
     1261 ttacatataa actcagcgtt acaaatttgg aatttacagg aagtgtgaca agaaagccaa
     1321 aacggtatac tgggaaaaaa gattaagaaa agaataaaga gctggtttta attgtaaaat
     1381 ttatggggaa ctaacatcag cttattgaca tgaatttaaa aataagtata ataatagttg
     1441 agtaattgtt caactattat tatttggagg tgaatatatg ccaaaaacgt cttatatttg
     1501 taattgcgat gtaattcatg aggatattgt gaatgatgtg aaatccaaga tgcagccaaa
     1561 agatgattat atccagttgg cttctttgtt taagctattt ggagatggaa ctagagtaca
     1621 aatcttacac gctctagaac agagtgagat gtgtgtatgt gatcttgcag tgctactggg
     1681 ggtaacaaaa tctgcaattt cgcatcagtt aaaggcatta cgccttgcga atctggtaaa
     1741 attccgtaaa gaagcacaga tagtttacta ctcactggca gatgatcatg tgaaagagat
     1801 tattgacaag ggatttgagc atctttggca gaaataatat tttttaacat tatagttgag
     1861 taattgaaca attaaacaaa ttataaggag attatcatga aacgcatatt tctattaaaa
     1921 gggttggact gtccaaattg ttccgcaaaa attgaaaaag aagtcggaga gttggatgga
     1981 gtgcaatcct cagtggtaaa tctgatgaag cagacgatta cagtcaatgt tactcagaca
     2041 gccgcagata cgatagccag tcagattgaa acgattgttt atagtcatga gccagatgtg
     2101 gaagttcagg aagaaaccgt tatgaatgtt acaaagagtt attcgttaaa agggttggac
     2161 tgtccgaatt gttccgcaaa aattgaaaaa gaagtcggag agttggatgg agtgcaatcc
     2221 tcagtggtaa atctgatgaa gcagacgctt acaatcaatg ttgctcagac agccgcagat
     2281 acgatagcca gtcagattga aacgattgtt catagccatg agccagatgt ggaagtttct
     2341 gaaattgtac aggaatctta tataccggaa aaaaagcagg aggccaatga atcctataac
     2401 aatgaggata agaagttgac agttcgttta gcgactggtg cagcaatcta tgccattggt
     2461 atggcattga ctgtttttgc gaaagtgcca ctgcctatcg agttagcttt tctcattgtt
     2521 tcttatgtta ttcttggtgg agatgttgta tggcaggctg tgaggaacat ttcaaagggg
     2581 cgtgtatttg atgaacattt tttgatgagt gtttctacga ttggggcttt tgttattggt
     2641 gaatatccag aagcagttgc tgttatgcta ttctatcagg taggtgaatt ttttcagtca
     2701 ttggctgtta agcgttccag aaaatctata tcagacttaa tggatatacg tccagattct
     2761 gctacagtaa gaagaaatgg ggaattgatt accatatctc cagaaaatgt ctccattggt
     2821 gagattatta ttgtaaagcc tggtgaaaaa attccattag acggtgtggt attggatgga
     2881 gattctatgc tggatacaag ggccttaaca ggagaatcag ttccgagaag tgttcataaa
     2941 ggagacgaag cactttccgg ttgtatgaat caaacgggtg tcttaatgat taagacaaca
     3001 aaagcatttg gtgaatctac ggcttcaaag attattgatc tggtggaaaa tgcgtcaagc
     3061 cgaaaagcac caacagaaaa ttttattact acatttgcac gttattatac acctgtggtt
     3121 gtaatcttag cagcttttct ggcgattctg ccaccgatca ttcttggcgg aggctggaca
     3181 gagtggattc gcagaggatt tgttttcctt gtggtatctt gtccatgtgc attggttatt
     3241 tcaatcccgc tgactttctt cggcggcatt ggtgcagcat ctaaacgagg tgttcttgta
     3301 aaaggaagca attatttaga ggcacttaat aatgtcagcg ttattgtgtt cgataaaacc
     3361 ggaacactta caaaaggtgt tttcaatgtg acggatattt tacctgcaaa tggattttca
     3421 aaagaacagg ttctggagta tgcggcagag gcagagagtt tttctaacca tcctattgca
     3481 aaatccattc ttgctgctta tgaaaaagaa attgatcagt cagtgatttc tgattataag
     3541 gaaatttcag gatatggaat cagtgtaatg gcaggggaaa agaaagtttt tgctggcaat
     3601 acgaaactta tggatacaga atgtatagag tacacaacct gtgaaaaagc aggtacaaaa
     3661 gtttatttgg ctgtagatgg tcaatatgca ggatgtattt tgataacaga tgaagtgaag
     3721 ccggacagta aaaaagcaat ttctgacctg aaacatatcg gcgtggaaaa aacagtcatg
     3781 cttaccggtg atgatgaaaa aattgggaag tctgttgcag aagaattgca gttggataaa
     3841 tattatgcac agctgcttcc tgaccaaaaa gtggaaaagg ttgagctttt agatagtaaa
     3901 aagagaccgg gaagcaaatt ggcttttgtt ggtgatggta tcaatgacgc tcctgtcctt
     3961 gcccgtgcag atgttggtat tgcaatgggt gggcttggtt cggatgcggc cattgaagca
     4021 gcagatgtag ttctgatgac agatgaaccg tctaagctgg tggacgcgat tgaagtagca
     4081 aaagcgacaa aacagattgt catgcagaat atagtgattg ctcttgggat taagagtgtg
     4141 ttcctgattc ttggcgctct tggtattgcg ggaatgtggg aagctgtatt tggtgatgta
     4201 ggcgttacca taattgctgt tttgaacgca atgagaattt tgaaaaaata ggaaatgagg
     4261 tggaaatgtg aaacgaaaac tgattctgtt agttgttacg attgtttttc ttgtaggttt
     4321 tggtgtcatt ttacattcac cgccttctat gattgatgca gtcacaggag caacaccgaa
     4381 gtcaaaaaag gcggctcaag cctccgcaca gttggaaggc tcttatgttc tcggtattaa
     4441 tatgatgtca gatggtctcg acaacgagaa cacccggaat aaattaaaag aattggcact
     4501 ggacgattcg gaaacaaatg aaacagatct catgaaaacg gacattagtt ttcggttata
     4561 tgtatctgag acggattatc cgcttgtcag ttatgctaag aaactctgtg acaggttgaa
     4621 acaggccggt ttttccgtag atctgaaaga gtacagtaac acaatgatgc tatcaagagt
     4681 ggtaagtgga aagtatgatg tattcctggc atcggatgat tttattgacg ttacaacgct
     4741 aacacagatg gactatatga tcatggacag cgaagaaatg aggtgagcgg gaatttatga
     4801 gaaaatggaa tacgattttg tctgttttaa tgcttctcat ttttatgatt catggaatca
     4861 tgggcagctt tatgctgaac ggagttggaa gtagtgcagg gaaacttctt gcatggattg
     4921 gtgttggcat tcttgttgtg catacggtga ttggtgtcat cctgacagtt cagagtttac
     4981 agacagcgaa gcaatcagga aaaatgtatc tgaaacagaa cgccatattt tgggcgagac
     5041 gagccagtgg gatggcaata ctgattctgc tgttattcca tattggcttg tttggaaagg
     5101 tgcagaatgg gacatatatt ttgttccctt ttacaacggt aaagatggta acccagcttt
     5161 tgttcgtagc ggcaatcttt gttcatattt ttatcaatat acgcccattg ctcgtatcac
     5221 tgggaatcat tagttataaa gaacgaagga gcgatattta tttgatcctt tcggtgcttc
     5281 ttctttttat agcgggagcg gttattttat attatattgg gtggcaatat ctatgagtaa
     5341 gacaattatt attataggtg ctggactggc aggactttca gcggctttgc aggcagcgga
     5401 aaatggatgc aatgtaaaac tggtttcctc ccttccgtca gagcgggcac agtctgttat
     5461 ggcggagggc ggtatcaacg cagctttgaa tacaaaagat gaaaacgaca gtcccgaaga
     5521 acattttaca gatacaataa aggcagcatg tggtctggca gatccaaatg cagtttgggg
     5581 aatgacacag gcagcaccgg agctggtgca ctggctgcta aaacttggag ttaaatttaa
     5641 catgagtggc tatgatgatg tggatctgcg gaattttggc gggcagaaaa agaaacggac
     5701 tgcttttgca cagagcgata ccgggaagca gatcatgaca gctatgatag acgctgttcg
     5761 caggaaagaa gcatctggta tggtagaacg gttcagccat cattctttcc taacacttcg
     5821 tctgtgtggc aatatttgtt gtggctgcgt aatcagggat gaatacagtc aggagactgt
     5881 ggaattaccg ggggatgcgg ttattgttgc caccggtggt atgcacggat tgtttggaaa
     5941 tacaacgggt tcgctgagca atacaggaga agtcaccgca gaattgttcc ggcttggtgt
     6001 tcctctggca aatagcgaga tgatccagta ccatccgaca actgtgaaat gtggtggaaa
     6061 acgcatgctc atcagcgagg cggccagagg ggaaggtggc aggttgtttg ccatgaaaga
     6121 tggaaaacaa tggtatttca tggaggaaaa atacccggag cttggaaatc tgatgccacg
     6181 agatattacc gccagagaga tatggaaggt cagccatgaa tcagaggtat ttcttgacat
     6241 gacggaaata tcggaggaga ttatttcaaa taagctatct ggtctggcag acgattgtat
     6301 gacctatctg cataaagata tacgaaagga accggtgtct gttttaccgg gaattcacta
     6361 ttttatggga ggcattctgg tggatgagca gcacagaacg ccgattcaga atctttacgc
     6421 tgccggagaa tgctgtgccc aatatcatgg tgccaaccgt cttggtggaa attctctgtt
     6481 aggagcgtta tacggaggac gtgttgcggc aaaatcagca tgtgaacagg cagatgtagt
     6541 agatctatct tgtgcgacac agatagattt tccaccagcg tctcaaattt cagaaataaa
     6601 gcaattaaac aaagtgatgc aggatactat gggcgttgtc agaaatgaga atacgttgtt
     6661 aaatgggatt caaacggtac aagcgctgac aggaaatctt ccattgcttg gcatggcagt
     6721 tctaaagagt gctcttgcaa gaaaagaaag ccgtggtgca cactggcggg aggattatcc
     6781 gaagagcaat gacgatgatt accttaaaac aacggtagcc agatttgatg gaaagcagat
     6841 acagatttcc tttgtacctg ttccagaaag gcggtgattc acttggtata taaaataaga
     6901 atcaggcggc aggagagtca gaaatcagac agttattggc aggaatttga gtttgacgga
     6961 agcaaaaaca gctctgttgc caatgttcta aaggaattga acagtagaac ccctttgaaa
     7021 gataattcag ggaatatagt tactcccatc agctgggaat gtagctgtat ggtgcgaaaa
     7081 tgtggggctt gcgccatgct gattaacgaa cgtccgaggc tggcatgctc tacatttcta
     7141 catacgttaa aaggttctac aatcaccttg gaacctttaa gcaaatttcc gcttgtaaga
     7201 gatttgatcg ttgaccggtc aattctgttt gaaaatttga aaaaactgaa cctttggctt
     7261 gaaagtgaag cttatatgaa tccgtggaca catgaaccga gataccagtc ggcacgctgt
     7321 ctgatgtgtg gctgctgcct tgaagtgtgt cccaacttct ctgcaaatgg gactttcgca
     7381 ggcgctgttg ctgcagtcaa cgcatttcgg attctgaatg aagaacagga aagcactcat
     7441 ttgaatgaga tttctgctga atataagaag aaatattttg agggatgcgg gaagtcgtta
     7501 tcttgtcatg atatttgtcc gattggtctg cctgtggaag aactgcttgt aaggtcgaat
     7561 gcagcggctg tttggggcaa ataaaatgga tgataaaagc tataatgaat gtatgaagag
     7621 aatcaaaaac ttaagacatg gatcacaccg gatcttgcga cggagtatct cgcaggagcc
     7681 gtgcttctcg gagcagctcc atgtaccgct atggtatttg tctggagtac gctgacaaag
     7741 ggaaatccag cttatacagt agttcaggtg gcatcaaatg acattattat attatttgca
     7801 tttgtaccga ttgtgaaatt tctgcttggt gtttctaatg ttagtgttcc gtttcagacg
     7861 ttatttatga gtgtggttct atttgtagta ataccacttg cagccggaat cataacaagg
     7921 ctgctggtag tcagaaagaa aggtacggaa tactttgagc agacttttct gcataaattt
     7981 gattccgcaa caacagtggg acttttgctc acgctgatac tgatttttat gtttcagggc
     8041 gaggtggtgc tggacaatcc actgcacatt atattgattg cagttccgct gatcattcag
     8101 acattcttta tattctttct ggcatttgga gtatgcagaa ttatcagact tccgtatgat
     8161 attgcagccc cggctggaat gattggtgca tcgaatttct ttgagctagc tgttgcagtc
     8221 gctgtagctt tatttggtac atcaagtcca gcggcactgg caactacagt aggtgtatta
     8281 acagaagtcc cggtaatgct tactcttgtg aagattgcaa acaaattaaa ggagaagttc
     8341 aagtatgaat aagaaaaaag ttgcttttat atgcgttcat aattcatgca gaagccagat
     8401 tgcagaagct ttgggaaaac atctggcttc ggatgtattt gaaagttatt cggcagggac
     8461 agaaacgaaa ctacagatta atcaggatgc agtccggatt atgaaagaat tgtatggaat
     8521 tgatatggaa gcagaaggac aatatagtaa gctgattgat gagataccag taccggatat
     8581 tgcaatttca atgggttgta atgtgggatg tccgtttatc gaaagaccgt ttgatgataa
     8641 ttggggactt gaagatccaa ccggaaagag tgacgaagag tttaagaagg ttattgatga
     8701 gataaggatg caaattttta tattgaaaca acgattggat gaatttgaag aaaactaaag
     8761 aagttgagaa attgcagttt gtcgaacgga tgagatacaa aaaaacatat aagaataatc
     8821 aacaaggcag gtggttttat aacaagactg tctgccttct tttatgccag cagaggctat
     8881 ttcaaagggg catccaaaag acatacaata tataggctca aatggcgaaa gtgcccattt
     8941 gggcctatta ttgcatgaat tcatatgtta catccagggc aagatccatc cgtgtattac
     9001 agtattgtca ttttgacaat tttgtattac ttacgagtag cagacttgat ggggattacg
     9061 tccccatacc cacgtgaaaa tataattgct ggcaattaca ttttagcaga cacgcaagcg
     9121 tttctgagta agtgttacag acaacaaaat aaggaaattt tgataaggca ttcacctgga
     9181 ataggtgagt gttttttgtt ttcaaatatt caattaaccg aaaaaattaa aaaaatttca
     9241 tcagggggct gtaaaaatgc ctctcagcgt ttcgtattaa tgaaagggta tttaggcggg
     9301 aaaaataaaa aactttcctc aagagcctgt atttatgccc ttcatctttt gaatatatgt
     9361 aaggacattt ttgagccggc ataaaaatga tttttacaat aattagaaac agaaatgagg
     9421 cgagaaaaga atcaaatatg aatacatgaa ggagtcagag cagatgcttc agtacttcca
     9481 gtttccgaag tttttattaa agctgcgaat ttctcaaact gcaaaattcc tttatatgat
     9541 tttgtatgac cgggcacgga tatcgagaaa gaatagctgg atagacaagt atggaaatgt
     9601 ttatctgata tttccaatag atgaattgtc tgttcaaatc gataaatgca aatcttctgt
     9661 aaaaacagcg ttgaaggaat tagatgatgt gggactattg gttcgcagat ccggtggatt
     9721 ttcaaaaccc aatcatttat atgtgaaaat tccatctgat gagataggtt tacagccggt
     9781 tgacaataag gcggttgaaa agatagttgc aacagagccg gaaaagccac cttcatctgg
     9841 tcgtaaaaat ggctgtggag gagtcggaaa tgtggcacct agtacaacga atattaaatt
     9901 gttgatagtt taaatagtgg ctacctcatc cggatcaatt tcatccattt tatatttata
     9961 tgtccaatga taaacaatcg ggtcagcatt gatctcatcg aagtagcgat atattcgttc
    10021 cgatagttcc tcctttgaat tgacacgaat gccttttaac atctgcttag tcattttgct
    10081 aaagaaactt tcaatcatgt tcagccacga ggtgtgtgtc ggtgtaaata caaacacaaa
    10141 tcgatcttct ggcaatactg caagaaactg acgtgtttcc tttgatgtat gagctgagtg
    10201 attgtccaat atcaatcgga tcgtgtcacc ttctggatat tttgcattga gcatttttaa
    10261 aaacttaata aaatcagaac ttttgtgtgt ctggctcacc aatggaattg cctcacctgt
    10321 caggagatca atacctgcaa gcaatgacag cgttccaagc cgcacatact cataatctcg
    10381 acggatataa ccgttttcct ctgttggatt atagtcgggg tatttgttgg caacagcctg
    10441 aatgccgggt ttttcatcat acgaaatagt atgtgtcaaa tgcccgttgt ccggtatgat
    10501 gatatttccg ttatcgtcaa actgcatctc cacctgttta taaaccagaa ggacatcatg
    10561 cattttattc tcaaagtcag gatcttttcg ttcaagataa tacttgattt tgaacggctt
    10621 aatctccatc tttttgagat atttttaaag ccatggtttt gtaaccgttt ttaaacgtgg
    10681 atagccggct tcttcagcat gtgcctgtat gtgtttgtgc agtgctgcta atgtccacaa
    10741 ttctgcggca tagccaagat cacagggctt ttggcaggct atactgacaa tccatgattt
    10801 tgcatcgtca gtaatttcag ccgggcggcc ggaacgttca tcatcaaata tagcaaggtt
    10861 aattccattg ttgagataac ggtcaataca gcggcggaca gtattcacac taacaccaag
    10921 accatctgca atagctttgt ctgttttggc ttcagacttc cataacagca tacgcgcacg
    10981 gtcaacaacc tgcgcttgaa tagttctggt tttgatcagt gatttcagat aggcacgttc
    11041 ttcatctgat attgttatac tataaggtaa tgctggcata attgacctcc ataaaatgta
    11101 tttattaagt tcattatacc agatactgaa actatcaaca acttaatttg tgttatacta
    11161 gctccttttc attcatggag ttgagaagta catcaatgtg ctttctgcaa ctgtgctcgt
    11221 cccgctgttc ttcccggtag aaaaactggt ctacggaaat atcgaacatg gtaacgagtt
    11281 tgaaaaataa attgaagctg ggatgttgtc ccttattttc aatattcata atcgtgcggt
    11341 ctgtcttgcc gaccagctcc gccacatagg cctgtgtcca gcctctttct tctctagctt
    11401 gtttgattgc cagcccgagc ccatgaaagt caaacctgat ttcatcttgg ttcattctca
    11461 tatcacccta tatcattgta catttcgggt tgaattatga gaatgtaatg aaatttgatg
    11521 ttaagtagta ttttattttg ctgtcagata gccacatgat tgaatatagc aaacgattgt
    11581 gataaagttg atacgaatat gccataaaat tatattctgc aaattgatca atgttaaaga
    11641 gaggtatttt atatgaatta cacaattcta atagttgatg acgatatggc tatcaatgat
    11701 atgcttgtta aatatcttcg gaaaaatggt tatataacat attctgctta ttcaggaaca
    11761 gaagcccttc tttttcttga aaagcaaaaa gttaatctga ttattttgga tttaatgctt
    11821 cccggtcttt ctggcgaaca agttttagta gaaataaaga aaacaaaaaa tgtacctgta
    11881 atcggtctat ctgcaaaaga agattctaaa agtaaaattt tcttattgaa aaacggtgct
    11941 gatgattatg taacgaaacc cttcgatata gaagaactac ttgcaaggat tgaaacgatt
    12001 ttgcgacgga tttatgaaaa tcaatataca tcaaattcct tgttatgttg tggcgattta
    12061 aatttagata caataggaat ggaggccact ctaaaaaatc aaaaattgcc ccttacaaaa
    12121 aatgagtttg ctatattgaa aatgcttatg gaacatccgc aacaagtatt tacgaaagat
    12181 atgatttatg agcaattatg gaatgaaact ttagagggaa ctgaaaatgc tatcaatgtt
    12241 catatcagca acttacgcaa aaaaattgct gcaatagata atagtaaatc atatattaaa
    12301 acggtttggg gaattgggtt taagatggac atataatctt tatgaaatcc ttagatttag
    12361 aaaataattt acttaaactt atcccttaca ctaaaaccac aaggagggat atatcatgga
    12421 atatatatta agaacgaaca cagtatctaa aaaatacaca aattattatg ctgttgataa
    12481 agtatccatt tctattaaaa aaggcgaaat atatggcttg attggagaaa atggtgctgg
    12541 taagtctact ttaatgaaaa tgattgcagg tttggttgaa ccatcagaag gctctattga
    12601 actatttgga aattttgttc cccagaccga gcgttatcgt attggttgtg tgattgaatc
    12661 tccggcactt tatgcagaat taaccgcaaa acaaaatttg gaagtattta gaaaagcata
    12721 tggactgtca agtaaagaat ctgtacaaca aattttaaag caggtgggtc tgtcacaata
    12781 tgaaaataaa attgtcaaaa aattttcatt aggtatgaaa cagcgtttag ccattggcgt
    12841 tgccttgttg ggaaatcctg attttctgat tcttgatgaa cctatcaatg gcttagatcc
    12901 gactggaata caagatatga ggaatttctt attaaaacta aatagggaag aacatattac
    12961 cattatgatt tccagtcata tcttggggga attgtcaaaa attgcaacaa aatacggcat
    13021 tattaaaaat ggcaagctga ttgaagaaat cactgcaaaa gaattaaatg aaaaatgtca
    13081 atgttgttta aaaattaagg catcagatac tgcacaggcc gctattttaa tagagaaaaa
    13141 tctccatact aaaaactacg aaattctttc cgataataat attcggattt ttgaatatgt
    13201 agacaatccc ggaattgtaa actccttact ggttaatcat ggaatttctg ttgatgaatg
    13261 tactgtaaca aaggagtcac tggaagatta ctttaatgaa ataggtaatt gcgaaactcg
    13321 cggtgctcgt tcgtaacctt gaaccaaaac aaggaagaat tcgcgaagag cacgactt
//
