LOCUS       gnlProkkaNHEHCBFB_8    12781 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NHEHCBFB_8.
ACCESSION   gnlProkkaNHEHCBFB_8
VERSION     gnlProkkaNHEHCBFB_8
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 14:49:48
            Original ID  :: gnl|Prokka|NHEHCBFB_8
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12781
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12781
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[459:2781]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      460..2781
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..12781
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12781
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             460..2781
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     665.6; E-value: 2.1e-201)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_1"
                     /sec_met_domain="DUF4135 (E-value: 2.6e-78, bitscore:
                     256.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.9e-51, bitscore:
                     167.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGISCRTVQY
                     LSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAHGEYPVI
                     IDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNSRVLISA
                     MGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYTECIIRG
                     FCRAYMVTMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSRECRKALL
                     NVIHKEGESSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLPCTPYES
                     WRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIYSQIRKI
                     VHRICSRAIIREQSVGWTGLQFWDNGHWNLRSGGIYLYDGISGTVLFLAKYLHDFEEKN
                     ASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLTGKRVWM
                     IYAEKHFSIIERVWKEDSQLDYLSGNAGAIVMAVMLYKETGNLKYYEIAADMEKDLWKK
                     GQETGNGYGWRLKGTDGPLAGMSHGNSGFMMAYAALYECNHKVEYADKIQLLLRYEDSL
                     YSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLNAADSLF
                     YGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAKISGTEY
                     LNLAFMNGISGTGMALMEIL"
     CDS             complement(2834..3358)
                     /locus_tag="ctg8_2"
                     /transl_table=11
                     /translation="MKTLTELIQNCQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIARKLKLSRQYVNRMKK
                     KLILKYISENK"
     CDS             3660..3899
                     /locus_tag="ctg8_3"
                     /transl_table=11
                     /translation="METTVMNVAVSHGIWAVLAVFLLVYIVKSNEKRDEKQEEREKNYQ
                     SVIEKLTEKLEILHQVQSDLSEIKENLFGKHKQE"
     CDS             4074..4193
                     /locus_tag="ctg8_4"
                     /transl_table=11
                     /translation="MGNNVKSDIVVLSKTGKVKNRYRLSEPQYGITYFGKSVK"
     CDS             complement(4350..4421)
                     /gene="allorf_04350_04421"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_04350_04421"
                     /protein_id="allorf_04350_04421"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNICNYRIKRILMGMSVFACISD"
     CDS_motif       complement(4365..4421)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MNICNYRIKRILMGMSVFA"
                     /locus_tag="allorf_04350_04421_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4350..4364)
                     /prepeptide="core"
                     /locus_tag="allorf_04350_04421_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="418.5"
                     /monoisotopic_mass="418.2"
                     /core_sequence="CISD"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNICNYRIKRILMGMSVFA"
                     /leader_location="[4364:4421](-)"
     CDS             4474..6588
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="MKEYKVITALFLSAVMLGTAPLTVWGAESFSTGESFSDGTENIPD
                     IVTDSALSGESSERDYELSIETGTDVELTESDFYDPEFRVEKYVKVRNSGKKETRVRVD
                     ASGLKNFEVDDQMAKWSEDYEEQDSKRLLKPGETLDFFVLPKQEYGTYDETFDFLADDG
                     SRYPVHITMNREKNPTEKKSLEITEKSSESFPIMHWGYKTLPEARIYVLKNFTDMNMEL
                     SFDYSKDCSVSLSGNTSLAPGESTELSLCPQMGLPVGEHDLGVTVTAKTATGDTITKKI
                     WDSFRVDSRTFQGLVDTIEPVTGITNGVEKTADALHLPSVLKVYGAEVDGEKTTFSADV
                     KWDVENCAYNPKNTASQSFTVNGQLELREGENNEELDTSVKIKVQVDAYKALNRPVIDP
                     TWTRVITNYAELSLRDISNEADGYFFVAAESQKELEKGNYIAQVKVAKSELNHYPKLKY
                     IPEGTHYLYCRAYKEESGHTEKYGEWSEGFLLKVNIKTPNAPVVQKLQVKKNDVKIILG
                     SNTEELDGYDVVAARSKDGDEPSDYIKVQCRYSGNSKELILKGVPKGNWYIGVHGYKYL
                     DGSNKKVLSKWAEVQKVTVKTSLVTGKPAVKSAKVSRQGTKRKVTVKFTVPKACDGTDW
                     VLAKKVSQSEDGSYTYVSGYAYTKKNQTKTTVIFKNVKPGVYYLTGRAYVKGYAKNYTK
                     WSEVKKVVVK"
     CDS             complement(6611..6799)
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MPGTLTFSVVNWKESDAECTFTVVNSGFGYTTQLQNKYYHTSFGL
                     FILTNNTFFFDIYAEKN"
     CDS             7327..8043
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 212.9; E-value:
                     8.4e-65)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MSEMTDAYVKLDKVSKIYGTKEVKIVAVDEISFEIAKGEFVVIVG
                     PSGAGKTTVLNILGGMDQATSGEVLVDGRNIARYNSRQLTSYRRNDIGFVFQFYNLVPN
                     LTALENVELALQICKNPLDAREVLEEVGLKDRLTNFPAQLSGGEQQRVSIARALAKNPK
                     LLLCDEPTGALDYQTGKAILKLLQDMCRDRGMTVIVITHNSALTPMADRVIKIKNGKVS
                     RMTMNDHPTPIEEIEW"
     CDS             8044..11829
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MISMKAMHKDFWMEIRKSKARFISIFMIVALGVAFFSGIQASSPD
                     MRFSGDAYYDETNLMDIKVVGTLGLTEDDVAAIKQVDGVENAEGAYGTDVMCGEGEKQK
                     VLHVEAVDQTMNRISVTEGKAPEKSGEIFLDCIFAESNGYKVGDQITLKEGGDSELLKK
                     TDYTVVGLGESPLYISYNRGNSTLGSGEVNGFAYVLPEDFGQEVYTQIYVQAHGAQDLI
                     SYTDAYDSLIERVQEQVEGIEAERCQVRYDEIVEEANDKLADARQELEDGKKEADEKLA
                     DARKELEDGEKKLKDGKKEYKDGKKKLADAKKELEDGKARLADAKKELEDGRSQLASAK
                     EQIASGRAQIASAKEQLNAGWAEVSENQAKLDDGKAQLEDGKNQLSAGEKKIADAKTQL
                     TQSQQELDNGKAQIQSGREQIAATRQDLNAKKESCNQGLAQIEQQEAGLAEGEAQLEGA
                     RSQLAALQAQYEQAQASGTYSEEDLAALAAQVSAYQEQVDSQAAQLEASRNQIAAARSE
                     LESGLSQVESGLAQLDAKEAELNQQEAAFPDAQAKIDAGWKEVKAQEKKLEPARKEIQE
                     KEAQLESAQEQIDAAKAKLNSSQAQLEEKEAELASGEAQIRENEGKLASGEKEIADNEQ
                     KLRDGEKEISENEQKLKDSRKDIKKAEKDLEEGKKEYEDGKRDAEKEIADGEKKIQDAQ
                     DEIDDISMPEWMVTDRNDLPEYSDYGDNADRMRSIGQVFPVIFFLVAALVSLTTMTRMV
                     EEQRTQIGTMKALGYGKYAIASKYLLYAFLATVGGSILGILIGEKILPLVIINGYGIMY
                     KGMMNNIQIRYEFKFAMIAAGAATVCTVGATIFSCYRALAETPASLMRPPAPKEGKRIL
                     LERIPLFWKHLNFTWKSTLRNLFRYKKRFFMTIFGISGSMALMLVGFGLRDSIMDIARR
                     QYQELQHYTGTIIDDEDATDKERQELDEFLKNNSQIERYTHVQFTKMSVPRNKSNISVY
                     VYVPENLETFNKDVTLQDRKTKEKYKLTDAGTVISEKTATLTGLKVGDSMTITKDGKNY
                     ETKIAAVTENYMGHYIYMTGNVYEQIFGEKPDYSATVFTVKEEYKESESEVGNEILKYP
                     AALSISYTSSLEAQLHRMLGALDTVIIVLIISAGMLAFVVLYNLNNVNITERQRELATL
                     KVLGFYDAEVSAYVYRENVILTFIGVLAGAVFGIFLHRYIIRTVEVDAVMFGRNINPVS
                     FLYCGLLTIGFSMIVNLFMHQKLKKIDMVESLKSVE"
ORIGIN
        1 cttttaaaac cccttccggc aacggaaagg tctttactgg aggcaaaagt ccctcctgta
       61 aagcgtagaa cctcatgtgt ttatgcagat ctgaggaaac tccattcaga aatggaactc
      121 ttaaaagcag catagataca ggcagatata cagcggacta cctgtaatgt ggaaaccagc
      181 catatctggc atggaaaaag cacataactg tgcagaccta agttacaggc gtatccgccg
      241 atatttagtc tgacgcctaa agcgtccgga agcacgtgac tttagccatg tgaggttcac
      301 ttaaaaaata actctatcca gagagcagaa tgtgaaatca ggaaatctct ttatgcagaa
      361 aaagaacaga tacaaaaaat attctgtgat ggaagaaagt tttccgggac tgtgggaatt
      421 tacatgtcga aaggcgatac acacagagga ggacgaagtg tggcgaaggt agaattggat
      481 aatggaacaa ttctgtacta taagccacat agtcttgata agaatataaa atatcaggaa
      541 ctttataact atttatgcag aaaaacagga atttcctgca ggacggtaca atatttatct
      601 catgattcct atggatggga agaaaaaatt gagaatattc cctgtaaaaa cgaaagtgag
      661 gtggagcatt attatttcag aatgggcata catctgtttt tgggatatgc ccttggagca
      721 acagatcttc atggtgaaaa tattatcgca catggagaat atcctgtgat tatcgatatg
      781 gagacatatc cgggatattt aaaacaacaa tcagaaaaag acggaagtag tgtagaagaa
      841 aaaataaaca aaagtacaga aataaaattg gcaaattcgg ttatacatac aggaatgctc
      901 cctgttctca catggggcag aggaaacagc agagttctta taagtgcaat gggaacagag
      961 gaaaagataa aaacgccgtt taaacttcct gtggtaaagg atgataaaac atctgatatt
     1021 cacatagaat atgaacctgt ggaaatgcag ataaaggaat gcattgtaag actaaatgat
     1081 caggttatca atgcggcaga ttatacggaa tgcattatca gaggattttg cagggcgtac
     1141 atggtgacaa tggcagataa gaaagtggag gtgatgttgt ccggcttttt tgacggacgt
     1201 tccagagttg tactgcggca tacccaacag tatgcaatgt atcttatggc ttcgtttcat
     1261 ccggattata tgaagtcaag agaatgcagg aaagctcttt tgaatgtgat tcacaaagag
     1321 ggggaatctt cttttatgaa agagattcat gattatgaaa ttgacagcct tctggaaatg
     1381 gatataccct gctttgagat tgatgcgaac agcagatctg tttatgatgg aaatggcgga
     1441 gaacataaag aatatctgcc ctgtactcct tatgagtcat ggcgaatgca tatgaagcag
     1501 atgagttact ctgatatgga atgtcagtgt gattatatca ggctgtccat ggaaatgctg
     1561 aaggcatctg atggaaagaa aaagatgttt ccgaccagga taaagggata tgacacagat
     1621 aaagagcgca aaatatacag tcagatcaga aagatagttc atcgaatctg cagcagagca
     1681 attatccggg aacagagtgt tggctggaca ggactgcaat tctgggataa tggtcactgg
     1741 aacctcagat caggtggaat ctatttatat gatggaatat cggggacagt cttgtttctt
     1801 gcaaaatatc ttcatgattt tgaagaaaag aatgcaagtg cagaagaaat ttatcatctt
     1861 gctgttttga gattgaaagc ttatacagat gaaatacaca aaaaacagat ttatgataaa
     1921 aatcttctga caggtattgt aaatggagaa agctcggtgg tatataccta tctttatctg
     1981 tttaaactta caggaaaaag agtgtggatg atttatgcgg aaaagcattt cagcattatt
     2041 gagagggtat ggaaagaaga ttcacaactg gattatctga gcggaaatgc cggagctatt
     2101 gtaatggcag taatgttata taaagaaacc ggaaatctga aatattatga aatagcggca
     2161 gatatggaaa aagatttgtg gaagaaagga caggaaaccg gaaatggata cggatggaga
     2221 ttaaaaggaa cagacggacc gctggctgga atgtctcatg gcaacagtgg atttatgatg
     2281 gcttatgcag cgttgtatga atgtaatcat aaagtggaat atgctgataa aatacagctt
     2341 ttgctgagat atgaggattc tttgtactca gagaaagccg gaaactggaa ggatttacga
     2401 gagagttcag gggaaagctt catgaatgca tggtgccatg gggcgccggg aatcctgctt
     2461 tcacgaatga aactggaaga gctgtttcct gaggatatgc agattaaaaa agacaggtta
     2521 aatgctgcag actctttgtt ttatggagaa caggatgaaa aaatttgtct gtgtcatggg
     2581 atgtccggga atttacttat tatgaagaag tatcttcgaa aatatggtaa taaaaaaatg
     2641 aaggagcaat atgaggcgtt atgtgactgc cttttatttc aactggatca cccggcaaaa
     2701 atatctggga cagaatatct gaatctggct tttatgaatg gcatttccgg tacgggaatg
     2761 gcattaatgg aaattttatg aaaactaagg gaacacctgc agactgtaaa tttatggtca
     2821 gcaggtgttt cttttatttg ttttcggaaa tatatttgag aattagtttc ttcttcatcc
     2881 gattgacgta ctggcgggac agcttcagtt tccgggcaat ctgggcatcg cttttatcct
     2941 gataaaagta catggacaga atttttctct ggacactgtc cgaagggtaa gagttgatat
     3001 atgcggttac atcataatag gtgtcatcaa aactgtcggg agcctgtaat gaaacagaac
     3061 aagaatcaaa atcatctttt tcaggttcgg aaagacaact gcggcaaagg gaacgatatc
     3121 tgttttcgac agaggtctgc atgtatctga tacattcacc ttctgaggat gaagaactta
     3181 aatatggcaa tgtctttaac aaagtaagat acaattcctg tgtggaatct tcacgttcca
     3241 tgcagtgaat ccgggatgca tatcctttca caagcggttc catacgtttg agaatttcac
     3301 tgtctgaatc tgggatacca ttttgacaat tttggataag ttctgtcagt gttttcatag
     3361 gtatctacct cctttttagg ggaagtagta agaaaactgc tgatcagaaa ctaaaaaaga
     3421 aaaaaattat gagtttacaa atggaagaga aaaaactctt tattaagtga gtttgcaaat
     3481 tcaaattaat gataagagga gaaaaaatat atggtaaaaa gagattggta gaataattgt
     3541 agagaataaa actgtgcctt aaattggaac ggtaataata agaccagaaa agacttttag
     3601 tggatggaat atagaaaaaa atgcgtaata aaagaagatt aagaggaggg aggtgaacta
     3661 tggaaacaac ggttatgaat gtggcagttt cgcatggaat ctgggcagtg ctggcggtat
     3721 ttcttttggt ttatattgtg aaatcaaatg aaaaacgaga tgagaaacag gaagagcggg
     3781 aaaaaaatta tcagtctgta atagagaaac tgacagagaa attagagatt ttacatcagg
     3841 tacaaagtga tttatcagaa atcaaagaga atctttttgg taagcataag caggagtaaa
     3901 aattcaggta taaaattgtc aagggaaaat ttattctttg aggtttgcaa agctgaaatt
     3961 aagaactctt tatcaagtag aatttgcaaa ttcgaaaaaa tataaatttc aggaggaaat
     4021 gaatatggca ggtacaatgt cagaaaagaa atttatatgt ttgtggatat acaatgggaa
     4081 ataatgtgaa atcagatatt gttgtattat caaaaacagg taaagtaaaa aatagatatc
     4141 gtctttctga gcctcagtat ggaattacat attttggaaa atcagtaaaa tgatatgagt
     4201 tcattttaat gaataaatgg catgaggatg aaggcggcat tgaaagtgaa aaaatctttt
     4261 tgataaaata ggaaaaagaa atagaagctc tctctacaaa atgaatgtca cagtggggag
     4321 ggcttttatc attcaggcaa gaaaacagat taatccgata tacaggcaaa aacactcatg
     4381 cccattagaa tacgttttat tctataatta cagatgttca tataaaaggt ggtatactat
     4441 aataataaat atcattgaat ggaggaaaaa gagatgaaag aatacaaggt tataacagca
     4501 ctttttttgt cagcagtaat gctgggtaca gctccattaa ccgtatgggg agcggagagt
     4561 ttttcgacag gggaatcttt cagtgatgga acagaaaata ttcctgacat agtaacagat
     4621 tcggctctgt ctggtgaatc ttctgaaaga gactatgagt taagcataga aacaggtacg
     4681 gatgtagagc ttacagaaag tgatttttat gatccggaat ttcgtgtaga gaaatatgtg
     4741 aaagtcagaa attcaggaaa aaaagaaaca agagtccggg tagatgcttc tggtcttaag
     4801 aattttgagg tagatgatca gatggcaaag tggtcagagg attatgagga acaggattcc
     4861 aaaagactgc tgaagccggg agaaactctg gacttttttg tactgccaaa gcaggaatac
     4921 ggaacatatg atgaaacgtt tgatttcctt gcagatgacg gaagcagata tccggttcat
     4981 atcacaatga acagagagaa gaacccaacg gaaaagaaga gtctggaaat taccgaaaaa
     5041 tcttccgaga gtttcccgat aatgcactgg ggatataaga cacttccgga agccagaatt
     5101 tatgttctaa aaaattttac ggacatgaat atggaactgt ctttcgatta cagcaaagac
     5161 tgtagtgtat cattatccgg aaataccagt ctggcacctg gagagagtac agaactgagc
     5221 ctttgtccgc agatgggact gccagttgga gaacatgatc ttggagtgac agtgactgcg
     5281 aaaacagcga caggagatac tataacaaag aagatttggg attctttcag agtagattca
     5341 aggacatttc agggactggt ggataccatt gaacctgtga ccggaattac caatggcgta
     5401 gaaaaaactg ctgatgcttt acatttgcca tcggttctta aagtctatgg tgctgaagtg
     5461 gatggagaaa aaacgacatt ttctgccgat gtaaaatggg atgtggagaa ttgcgcatat
     5521 aacccgaaaa atacggcgtc tcaaagtttc acagttaacg gacaattgga actgcgtgaa
     5581 ggtgaaaaca atgaagagct ggatacgtct gtaaagataa aggtacaggt ggatgcgtac
     5641 aaggcgttga acagaccggt gattgatccg acatggacca gagtgatcac aaattatgca
     5701 gaactttctt taagagatat ttctaatgaa gcagacggat atttttttgt agcagcagaa
     5761 tctcaaaagg aactggaaaa aggaaattat atcgcacagg tgaaggtcgc aaaatctgaa
     5821 ctgaatcatt atcctaaact gaaatatatt cctgaaggga cgcattatct ctattgcagg
     5881 gcatataaag aggaaagtgg tcatacggag aaatatggtg aatggtctga aggatttctg
     5941 ttaaaggtaa atataaagac accaaatgca cctgtggttc agaaactaca ggtgaagaaa
     6001 aatgatgtta aaattatcct tggcagtaat acagaagaac tggatggtta tgatgttgtt
     6061 gctgccagaa gtaaagacgg ggatgagcca tcagattata taaaggtaca atgcagatat
     6121 tcaggaaaca gcaaggaact cattctaaaa ggagtaccga aaggaaactg gtatattggt
     6181 gtacatggct ataaatatct ggatggatca aataaaaaag tactgagtaa gtgggcggaa
     6241 gttcaaaaag taacggtaaa gacaagcctt gtaacaggaa aaccagctgt taaatcggca
     6301 aaggtttcca gacagggaac aaaaagaaaa gtaacggtga agtttactgt accaaaagcc
     6361 tgtgacggaa cggactgggt actggcaaag aaagtatctc aatctgaaga tggaagttat
     6421 acatatgtca gcggttatgc ttatactaag aaaaatcaga cgaaaactac agtcattttt
     6481 aaaaatgtaa aacctggagt ttattatctt acaggacgtg cttatgtaaa aggatatgca
     6541 aaaaattata cgaaatggtc agaggtaaag aaagtagttg tgaagtagaa aagtgattta
     6601 gaccagaaat ttaatttttt tctgcatata tatcaaaaaa gaaggtgttg tttgtcagaa
     6661 taaataatcc aaaggaagta tggtagtatt tattctgcaa ctgtgtggta taaccaaaac
     6721 ctgagtttac gactgtgaat gtacattctg catcagattc tttccagttt acaacactga
     6781 aagttaatgt tcctggcata atttttgcct cctttaaatt ttttgaattt gcaaattcac
     6841 tatataaaga tgctgctttt ggtgatttgt aaaccataag tgtgtatatg agcatgattt
     6901 ttttctttca tgcggaaatt aggtaagaat aaaaataaag attcgaggtc agatgatgca
     6961 tgtttattcc ttttttatat tttcggcatc agtttaatgt aaaataataa cgggtaaaga
     7021 agatataaga tgttctggta catacaatta agaagaaagg aagcttgtgc tgtgcatagt
     7081 caaaatgatg aaccgcctga gatgatcagg cggttttgga atatctggat tttttatgaa
     7141 tattttattt ttaattacag gtataatgtg ttacaataaa tataaccatt aagactacca
     7201 ggcaggtcag aatttgacct gcctgtaaat aaatacggaa gtaaatcggg gtcaaaagaa
     7261 tcgttaataa ttctaacaaa ataaaattac cggtgtagca aaaataaaat tacaggggaa
     7321 atgcggatga gtgagatgac agatgcatat gtaaaactgg ataaggtttc caagatatat
     7381 ggaaccaaag aagtaaagat cgttgcagta gatgagatca gctttgagat tgccaaggga
     7441 gagtttgtag tgatcgttgg tcccagcggt gcgggcaaga cgacagtgct gaacattctt
     7501 gggggtatgg atcaggctac cagcggagag gttctggtgg atggaaggaa tattgccaga
     7561 tataacagca ggcagcttac cagttatcgg agaaatgata ttggatttgt attccagttc
     7621 tataatctgg tgcccaacct tacagcactg gagaatgtag aactggcact gcagatatgt
     7681 aagaatccgc tggatgccag ggaggttctg gaggaagtgg gactgaagga cagactgacc
     7741 aatttcccgg cacagctttc cggtggtgag cagcagagag tttccattgc cagagcactg
     7801 gcgaagaatc ccaagctgtt gttgtgtgat gagcccacag gtgcactgga ctaccagact
     7861 ggtaaggcaa tccttaaact tttgcaggat atgtgcaggg atcgtggaat gacagtgatc
     7921 gtcattaccc ataactcggc gctgacacct atggcagacc gtgtgatcaa gatcaagaac
     7981 ggcaaggttt ccaggatgac gatgaatgac catcctacac cgattgagga gatagaatgg
     8041 taggtgatta gtatgaaagc aatgcataaa gatttctgga tggagatacg caagagcaaa
     8101 gccagattta tttccatatt tatgatcgtt gctctgggag ttgcgttttt ctccgggata
     8161 caggcctcat caccggatat gcgcttctca ggcgatgcct attatgatga aaccaatctt
     8221 atggatatca aagtagtggg aactctggga ctgacggagg atgatgtagc tgccattaag
     8281 caggtggacg gagtagagaa tgcagagggc gcctatggta cagatgtaat gtgtggagaa
     8341 ggcgagaagc agaaggtact tcatgtggaa gctgtggatc aaaccatgaa ccggatctca
     8401 gtgacagagg gaaaagctcc ggaaaaaagc ggagagattt ttcttgactg tatttttgct
     8461 gagagcaatg gatataaggt gggtgatcag attaccctga aagagggcgg agacagcgaa
     8521 ctgttgaaaa agacagatta cacagttgta ggtttaggag agagtccgct ttacatatcc
     8581 tataatcgcg gaaattccac tctgggttcc ggtgaggtta atggatttgc ctatgtgctc
     8641 cctgaggatt ttggccagga ggtttataca cagatctatg tgcaggctca tggggcacag
     8701 gatctgatca gctatacaga tgcttatgat tccctgatag agcgagtgca ggagcaagtg
     8761 gaggggattg aggcagaacg gtgccaggtt agatatgatg agattgtaga ggaagctaat
     8821 gacaagcttg cagatgccag acaggaactt gaagacggca agaaggaggc tgatgagaag
     8881 cttgcggatg ccagaaaaga attggaggat ggcgaaaaga agttaaaaga tggcaagaag
     8941 gaatataagg atggcaagaa aaagcttgca gacgcaaaaa aggaactgga ggacggaaaa
     9001 gcccggcttg cagatgcaaa gaaggagtta gaggacggca gatcccagct tgccagtgcg
     9061 aaagagcaga ttgccagtgg cagagcacag atcgcatctg caaaggaaca gctgaatgcc
     9121 ggatgggcgg aggtttccga aaaccaggca aagcttgatg atggaaaggc tcagcttgag
     9181 gatggcaaga accagttaag tgccggtgag aagaagattg cagatgcaaa gacgcagctt
     9241 acccagagtc agcaggaact tgacaatggc aaggcgcaga tccagtcagg cagagagcag
     9301 attgcagcaa ccagacagga tttaaatgcc aaaaaggaaa gctgcaatca gggacttgcg
     9361 cagattgagc agcaggaggc cggacttgca gaaggagagg ctcagcttga gggtgccaga
     9421 agtcagcttg cagcattgca ggcacagtat gagcaggcac aagcttcagg cacatattcc
     9481 gaggaagacc tggcggctct ggcagcacag gtttccgctt atcaggagca ggtggacagt
     9541 caggcagccc agctggaagc atccagaaac cagatcgcag cagcaagaag tgaactggag
     9601 agtggtttaa gccaggtgga gagcggactg gcccagcttg atgcaaagga agcagaactg
     9661 aaccagcagg aggccgcatt tcccgatgcc caggcaaaga ttgatgcagg atggaaagag
     9721 gtgaaggctc aggagaagaa gctggaacca gccagaaaag agattcagga aaaagaagcc
     9781 cagcttgagt cagcacagga acagatcgat gctgcaaaag caaaactaaa ttccagccag
     9841 gctcagttag aggagaagga ggcagaactt gcttcaggag aagcacagat ccgggagaat
     9901 gaagggaagc ttgcttccgg cgagaaagag attgccgaca atgaacagaa gctgagggat
     9961 ggagagaaag aaatctcaga gaacgaacag aagctgaagg attccagaaa ggacatcaaa
    10021 aaagctgaga aggatctgga agaaggtaaa aaagaatacg aagacggaaa gagggatgca
    10081 gagaaagaaa tcgcagacgg tgagaagaaa attcaggatg ctcaggatga gatcgatgat
    10141 atcagtatgc cggaatggat ggtaacggac cgcaatgatc tgccggaata ttcagattat
    10201 ggggataatg cagacagaat gagaagtatc ggacaggttt tccctgttat ctttttcctg
    10261 gtggctgcac tggtaagtct gactaccatg acacgaatgg tggaggaaca gagaacccag
    10321 attggtacaa tgaaggctct gggatacggc aagtatgcga ttgcatccaa atatctgctg
    10381 tatgcctttc ttgccacagt gggaggcagt atcctgggaa ttctgatcgg agagaagatc
    10441 ctgcctttgg ttattattaa cgggtatggc attatgtaca agggcatgat gaacaatatc
    10501 cagatccgtt atgagtttaa atttgcaatg atagcagcag gtgcggcaac tgtgtgtacc
    10561 gtcggagcca ccattttctc ctgttacagg gcactggcgg aaactccggc atcactgatg
    10621 cgtcctcctg ctcccaaaga gggtaagaga atcctgctgg aacggatccc gcttttctgg
    10681 aagcacttga attttacatg gaaatctaca ctgagaaacc ttttccgata taaaaaacgt
    10741 ttctttatga caattttcgg tatttcggga agtatggcgc tgatgctggt aggctttgga
    10801 ctcagagatt ccattatgga tattgccaga cggcaatatc aggagcttca gcattataca
    10861 ggaacgatta ttgatgatga ggatgcaaca gataaggaga gacaggagct ggatgagttt
    10921 ctgaaaaata acagtcagat tgagagatat acccatgtgc agtttaccaa gatgagtgtt
    10981 cccagaaata aatccaatat cagcgtatat gtttatgtgc ctgagaatct tgagaccttt
    11041 aataaggatg taactcttca ggacagaaag acaaaagaga agtataagct gacggatgca
    11101 ggtacagtga tcagtgagaa gacggcaacc ctgacaggac tgaaagtggg ggacagcatg
    11161 accatcacaa aggatgggaa aaattatgag acaaagatcg cagcagtgac agagaattac
    11221 atgggacatt atatttatat gacaggaaat gtctatgaac agatcttcgg ggagaagcct
    11281 gactattctg caactgtgtt cacagtaaaa gaggagtaca aagaatcaga atctgaggtg
    11341 ggaaatgaga tcctgaagta tccggctgcg ttaagcatca gctataccag cagtctggag
    11401 gctcagcttc acagaatgct tggagcattg gatacggtaa tcatagtgct gatcatttct
    11461 gcgggaatgc ttgctttcgt ggttctgtat aatctgaaca atgtcaatat tacggaacgc
    11521 cagagagaac tggcaaccct gaaggtgctg ggattctatg atgctgaagt ttctgcctat
    11581 gtgtacaggg agaatgttat ccttaccttc atcggcgtac tggcaggagc tgtattcgga
    11641 atctttttgc acaggtatat tatccgtact gtggaagtgg atgcggttat gtttggaaga
    11701 aatatcaatc ctgtcagttt cctgtactgc ggactgctga caattggatt ctccatgatc
    11761 gtaaatctgt ttatgcatca gaaattaaag aagattgaca tggtagaatc cctgaaaagt
    11821 gtggaataaa cgatttgccg ctttattgca ggaaagaaga aatagaaaaa tacaggataa
    11881 aatgtgaaat atatcagata aaacacaaag aagaatgaaa atacaatagc gatttttgac
    11941 aaaataaaaa agtggggttg acgtattttt gtaactttgt tatagatggc tttatcaatt
    12001 aaaaacatac ggattgttac tgttaggaag gcaaaaccag aatctatggc tgagaaaatc
    12061 agtctgtaaa ttctggtttt tttatgttac agggaaatta cttcgtaatg ttcctgtaag
    12121 caggattctt tcttgttacg ttacagggaa attactccgc tgtcaggaaa catatcgttt
    12181 ggaaaaggaa agacatggat aatatcataa ttgaaaaagt gatcaataac aatattatct
    12241 cggcatatga gaaatccggt gcagaagtaa tcgtgatggg acgtggaatc ggtttcaaaa
    12301 agaaacaggg agaagtggtt cctgctgacc agatcagtaa aatctttcgc attaaaagcc
    12361 ggacactgac ggaacagttc aaggagctgc tggccaatat gccgctggaa cgagtgagga
    12421 tttcagacga gatcatctct catgcaaagg atcatctgaa attaaaactg aatcagagca
    12481 tttatgtgac gctgacggat catattaatt ttgcaattga aagagtgagc cagggaatag
    12541 aaccgcagaa tgcattattg tgggaaatca agcgctttta tcctcaggaa tttcaattag
    12601 gaatctatgc gttggagctg atccatgaca gacttggtat tcttctgccg gaggatgaag
    12661 caggatttat tgctcttcat ttcgtaaatg cagaatatgg tacagatatc cgggatgcag
    12721 tgaaatttcc ggatcagatg caggcaattg tggatattgt ggaacgtgat ctgggaatac
    12781 t
//
