## Fri Jul  5 04:25:50 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_028310745.1/GCA_028310745.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_028310745.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_028310745.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
NHEHCBFB_00002	635013.TherJR_0878	3.5e-06	50.1	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,260XA@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NHEHCBFB_00003	458817.Shal_0638	5.56e-21	94.7	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria,2QB5A@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Amidohydrolase family	hyuA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016787,GO:0016810,GO:0016812,GO:0042802	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
NHEHCBFB_00004	1235802.C823_02960	3.36e-112	334.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,24AE6@186801|Clostridia,25WG1@186806|Eubacteriaceae	186801|Clostridia	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
NHEHCBFB_00005	457412.RSAG_02735	1.73e-163	458.0	COG0406@1|root,COG0406@2|Bacteria,1U7UE@1239|Firmicutes,24F5B@186801|Clostridia,3WI6A@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NHEHCBFB_00006	457412.RSAG_02734	1.13e-205	571.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,249GM@186801|Clostridia,3WGAM@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
NHEHCBFB_00007	1121115.AXVN01000012_gene3092	0.0	1138.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia,3XZ6F@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
NHEHCBFB_00008	1121115.AXVN01000012_gene3091	3.6e-38	127.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,25HV0@186801|Clostridia,3Y0TI@572511|Blautia	186801|Clostridia	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
NHEHCBFB_00009	1121115.AXVN01000012_gene3090	1.05e-179	501.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,3XZG0@572511|Blautia	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
NHEHCBFB_00010	1121115.AXVN01000090_gene2572	9.16e-304	827.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,3XYRP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
NHEHCBFB_00011	1121115.AXVN01000090_gene2571	2.93e-138	390.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,3Y00P@572511|Blautia	186801|Clostridia	H	Thiamine monophosphate synthase	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
NHEHCBFB_00012	1121115.AXVN01000090_gene2570	0.0	873.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,3XZM9@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
NHEHCBFB_00014	1121115.AXVN01000090_gene2560	2.83e-62	190.0	COG1598@1|root,COG1598@2|Bacteria,1VH8E@1239|Firmicutes,2586D@186801|Clostridia,3Y0CI@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
NHEHCBFB_00015	457412.RSAG_02725	5.51e-200	553.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,3WGHY@541000|Ruminococcaceae	186801|Clostridia	L	8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
NHEHCBFB_00016	457412.RSAG_02724	9.65e-65	197.0	2E7YJ@1|root,332CZ@2|Bacteria,1VF30@1239|Firmicutes,24SCF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00017	457412.RSAG_02723	2.62e-158	443.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3WGWR@541000|Ruminococcaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
NHEHCBFB_00018	1121115.AXVN01000054_gene1871	6.37e-299	814.0	29WP9@1|root,30IA6@2|Bacteria,1V4GZ@1239|Firmicutes,24HWX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00019	457412.RSAG_02721	0.0	1496.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WH1C@541000|Ruminococcaceae	186801|Clostridia	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP_1	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
NHEHCBFB_00020	1121115.AXVN01000054_gene1873	1.21e-212	587.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24I3P@186801|Clostridia,3Y1VY@572511|Blautia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NHEHCBFB_00021	457412.RSAG_02719	4.24e-183	511.0	COG3290@1|root,COG3290@2|Bacteria,1VDUW@1239|Firmicutes,24QIG@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NHEHCBFB_00022	457412.RSAG_02718	6.43e-211	584.0	2EZ41@1|root,33SA8@2|Bacteria,1VSVN@1239|Firmicutes,24XVU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00023	457412.RSAG_02717	1.62e-169	473.0	COG3279@1|root,COG3279@2|Bacteria,1VC9Q@1239|Firmicutes,24PSE@186801|Clostridia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NHEHCBFB_00024	457412.RSAG_02716	0.0	1063.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3WH77@541000|Ruminococcaceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NHEHCBFB_00025	1121115.AXVN01000054_gene1879	3.75e-63	193.0	COG2026@1|root,COG2026@2|Bacteria,1V7AZ@1239|Firmicutes,24KDM@186801|Clostridia	186801|Clostridia	DJ	ParE-like toxin of type II bacterial toxin-antitoxin system	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE-like_toxin
NHEHCBFB_00026	1121115.AXVN01000054_gene1880	1.19e-80	239.0	COG2002@1|root,COG2002@2|Bacteria,1V8G8@1239|Firmicutes,24JVE@186801|Clostridia	186801|Clostridia	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00027	1121115.AXVN01000054_gene1881	1.34e-232	640.0	28K5V@1|root,2Z9UD@2|Bacteria,1V0GM@1239|Firmicutes,24EZ5@186801|Clostridia,3Y13M@572511|Blautia	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3878
NHEHCBFB_00028	457412.RSAG_02712	2.69e-186	518.0	COG2206@1|root,COG2206@2|Bacteria,1V23X@1239|Firmicutes,24GQ5@186801|Clostridia,3WKDD@541000|Ruminococcaceae	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
NHEHCBFB_00029	457412.RSAG_02711	4.4e-138	390.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,3WK2K@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
NHEHCBFB_00030	457412.RSAG_02710	1.59e-308	839.0	COG1379@1|root,COG1379@2|Bacteria	2|Bacteria	-	-	yqxK	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4178,PHP_C,UvrD-helicase,UvrD_C
NHEHCBFB_00031	457412.RSAG_02709	5.72e-113	323.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,24PEZ@186801|Clostridia,3WJE3@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NHEHCBFB_00032	457412.RSAG_02708	6.08e-106	305.0	2DV0M@1|root,32UY9@2|Bacteria,1VC55@1239|Firmicutes,24TS3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00033	457412.RSAG_02707	5.25e-106	306.0	2BZUE@1|root,31TAF@2|Bacteria,1URY6@1239|Firmicutes,24XVK@186801|Clostridia,3WQSR@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00034	457412.RSAG_02706	6.5e-73	219.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia,3WK33@541000|Ruminococcaceae	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
NHEHCBFB_00035	457412.RSAG_02705	2.87e-133	381.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia,3WI9G@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
NHEHCBFB_00036	1121115.AXVN01000054_gene1891	5.88e-31	110.0	2C1K5@1|root,3415T@2|Bacteria,1VY97@1239|Firmicutes,2522U@186801|Clostridia,3Y25V@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00037	457412.RSAG_02702	1.8e-223	617.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WHDB@541000|Ruminococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
NHEHCBFB_00038	1121115.AXVN01000054_gene1893	6.34e-164	461.0	2E77V@1|root,32VJN@2|Bacteria,1VA37@1239|Firmicutes,24P5M@186801|Clostridia,3Y1P9@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00039	457412.RSAG_02700	1.94e-110	318.0	2BWHH@1|root,33G8D@2|Bacteria,1VM1X@1239|Firmicutes,24W5T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00040	1121115.AXVN01000054_gene1895	3.36e-117	335.0	COG1595@1|root,COG1595@2|Bacteria,1VB8F@1239|Firmicutes,24PH6@186801|Clostridia,3Y1N5@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NHEHCBFB_00041	457412.RSAG_02698	1.02e-278	761.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,3WHB1@541000|Ruminococcaceae	186801|Clostridia	J	Threonine alanine tRNA ligase second additional domain protein	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NHEHCBFB_00042	457412.RSAG_02697	1.66e-213	589.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,24EHA@186801|Clostridia	186801|Clostridia	Q	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
NHEHCBFB_00043	1121115.AXVN01000054_gene1898	3.49e-270	741.0	COG3103@1|root,COG3103@2|Bacteria,1UG5Z@1239|Firmicutes,25NDX@186801|Clostridia,3Y048@572511|Blautia	186801|Clostridia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00044	457412.RSAG_02693	3.92e-123	352.0	COG3275@1|root,COG3275@2|Bacteria,1UJ12@1239|Firmicutes,24Q7D@186801|Clostridia,3WKDP@541000|Ruminococcaceae	186801|Clostridia	T	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS,ECF_trnsprt
NHEHCBFB_00045	457412.RSAG_02692	6.43e-194	536.0	COG0454@1|root,COG0456@2|Bacteria,1V37I@1239|Firmicutes,24IZQ@186801|Clostridia,3WNI3@541000|Ruminococcaceae	186801|Clostridia	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NHEHCBFB_00046	1121115.AXVN01000124_gene3954	9.4e-165	461.0	COG2755@1|root,COG2755@2|Bacteria,1VT0W@1239|Firmicutes,25BMQ@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NHEHCBFB_00047	1121115.AXVN01000124_gene3953	1.97e-151	426.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,3XZ99@572511|Blautia	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
NHEHCBFB_00048	1121115.AXVN01000124_gene3952	3.21e-32	113.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3Y0KZ@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
NHEHCBFB_00049	457412.RSAG_02688	1.16e-87	260.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,3WKJC@541000|Ruminococcaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
NHEHCBFB_00050	457412.RSAG_02687	1.79e-112	323.0	COG0712@1|root,COG0712@2|Bacteria,1UI0C@1239|Firmicutes,24G5C@186801|Clostridia,3WK3C@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
NHEHCBFB_00051	457412.RSAG_02686	0.0	961.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
NHEHCBFB_00052	457412.RSAG_02685	1.64e-206	572.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3WHJU@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
NHEHCBFB_00053	1121115.AXVN01000124_gene3947	0.0	911.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3XYVU@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
NHEHCBFB_00054	1121115.AXVN01000124_gene3946	6.42e-87	256.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,3Y0C9@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
NHEHCBFB_00055	457412.RSAG_02682	0.0	971.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia,3WJKE@541000|Ruminococcaceae	186801|Clostridia	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
NHEHCBFB_00056	457412.RSAG_02681	9.42e-232	638.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,3WGEJ@541000|Ruminococcaceae	186801|Clostridia	M	Linear amide C-N hydrolase, choloylglycine hydrolase family protein	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
NHEHCBFB_00057	457412.RSAG_02679	0.0	1612.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3WI2B@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
NHEHCBFB_00058	1121115.AXVN01000023_gene1769	1.05e-127	363.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	cpaA	-	3.4.23.43	ko:K02278,ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
NHEHCBFB_00059	1121115.AXVN01000023_gene1770	6.79e-249	682.0	COG1192@1|root,COG1192@2|Bacteria,1V11K@1239|Firmicutes,24FDX@186801|Clostridia,3XZ68@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
NHEHCBFB_00060	1121115.AXVN01000023_gene1771	1.33e-276	757.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,3XZAC@572511|Blautia	186801|Clostridia	U	flp pilus assembly ATPase CpaF	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
NHEHCBFB_00061	457412.RSAG_02675	1.43e-176	493.0	COG4965@1|root,COG4965@2|Bacteria,1V6PB@1239|Firmicutes,24JBR@186801|Clostridia,3WJUZ@541000|Ruminococcaceae	186801|Clostridia	U	Flp pilus assembly protein TadB	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
NHEHCBFB_00062	457412.RSAG_02674	9.06e-235	647.0	COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,24AN4@186801|Clostridia,3WJSN@541000|Ruminococcaceae	186801|Clostridia	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
NHEHCBFB_00063	1121115.AXVN01000023_gene1774	1.49e-32	113.0	2EHSI@1|root,33BI9@2|Bacteria,1VK7K@1239|Firmicutes,24UF9@186801|Clostridia,3Y0UH@572511|Blautia	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
NHEHCBFB_00064	1121115.AXVN01000023_gene1775	0.0	930.0	2BXNJ@1|root,2ZC8M@2|Bacteria,1UYM5@1239|Firmicutes,24ASZ@186801|Clostridia,3XZFX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00065	1121115.AXVN01000023_gene1776	5.5e-201	556.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia,3Y0C5@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
NHEHCBFB_00066	1121115.AXVN01000023_gene1777	3e-96	280.0	COG1989@1|root,COG1989@2|Bacteria,1VMFT@1239|Firmicutes	1239|Firmicutes	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
NHEHCBFB_00067	1121115.AXVN01000023_gene1778	2.07e-102	296.0	2EQ3G@1|root,33HPU@2|Bacteria,1VKDW@1239|Firmicutes,24V35@186801|Clostridia,3Y0MK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TadE
NHEHCBFB_00068	457412.RSAG_02668	0.0	952.0	COG1716@1|root,COG1716@2|Bacteria,1V550@1239|Firmicutes,24BVK@186801|Clostridia,3WRV5@541000|Ruminococcaceae	186801|Clostridia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
NHEHCBFB_00069	457412.RSAG_02667	1.07e-134	382.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,3WJRW@541000|Ruminococcaceae	186801|Clostridia	S	PFAM Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
NHEHCBFB_00070	1121115.AXVN01000023_gene1781	1.83e-164	459.0	COG3852@1|root,COG3852@2|Bacteria,1VA7P@1239|Firmicutes,24J8F@186801|Clostridia,3Y29E@572511|Blautia	186801|Clostridia	H	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NHEHCBFB_00071	1121115.AXVN01000023_gene1782	5.29e-95	276.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,3Y034@572511|Blautia	186801|Clostridia	FG	Psort location Cytoplasmic, score 8.87	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
NHEHCBFB_00072	1121115.AXVN01000023_gene1783	1.15e-122	350.0	2DUBI@1|root,33PTJ@2|Bacteria,1VRWC@1239|Firmicutes,24Y88@186801|Clostridia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
NHEHCBFB_00073	1121115.AXVN01000023_gene1784	5.23e-256	702.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,3XYKG@572511|Blautia	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
NHEHCBFB_00074	1121115.AXVN01000023_gene1785	4.24e-94	275.0	2EXFY@1|root,33QS9@2|Bacteria,1VU5K@1239|Firmicutes,24YDE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00075	1121115.AXVN01000023_gene1786	0.0	1100.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,3XZEM@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
NHEHCBFB_00076	1121115.AXVN01000023_gene1787	9.1e-54	168.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,3Y0NQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
NHEHCBFB_00077	1121115.AXVN01000023_gene1788	7.42e-162	453.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,3XZ1X@572511|Blautia	186801|Clostridia	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
NHEHCBFB_00078	1121115.AXVN01000023_gene1789	5.84e-86	253.0	2E5KN@1|root,330BS@2|Bacteria,1V5P2@1239|Firmicutes,24TCR@186801|Clostridia,3Y0HH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00079	457412.RSAG_02657	1.45e-280	766.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia,3WSRX@541000|Ruminococcaceae	186801|Clostridia	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
NHEHCBFB_00080	457412.RSAG_02656	0.0	1587.0	28IKE@1|root,2Z8M5@2|Bacteria,1TP2B@1239|Firmicutes,248C2@186801|Clostridia,3WI6Z@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	GcvP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
NHEHCBFB_00081	1121115.AXVN01000023_gene1792	0.0	997.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3XZID@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
NHEHCBFB_00082	457412.RSAG_02654	0.0	1509.0	COG2247@1|root,COG2755@1|root,COG2247@2|Bacteria,COG2755@2|Bacteria,1UKIA@1239|Firmicutes,25FXT@186801|Clostridia,3WMKI@541000|Ruminococcaceae	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00083	1121115.AXVN01000023_gene1794	0.0	940.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,3XZAQ@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
NHEHCBFB_00084	1121115.AXVN01000023_gene1795	1.06e-261	716.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia,3XZ47@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
NHEHCBFB_00085	457412.RSAG_02651	5.66e-297	814.0	COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,24E0A@186801|Clostridia,3WKD3@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
NHEHCBFB_00086	1121115.AXVN01000023_gene1797	2.46e-292	797.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3XYUR@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
NHEHCBFB_00087	457412.RSAG_02649	5.45e-232	639.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,3WJBS@541000|Ruminococcaceae	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
NHEHCBFB_00088	457412.RSAG_02648	4e-279	764.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia,3WJJV@541000|Ruminococcaceae	186801|Clostridia	L	DnaD domain protein	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
NHEHCBFB_00089	457412.RSAG_02647	0.0	923.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,3WGQ1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NHEHCBFB_00090	1121115.AXVN01000023_gene1801	5.33e-304	829.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3XZGS@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NHEHCBFB_00091	1121115.AXVN01000023_gene1802	1.23e-253	697.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3XZRM@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NHEHCBFB_00092	1121115.AXVN01000023_gene1803	3.27e-58	180.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,3Y05I@572511|Blautia	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
NHEHCBFB_00093	1121115.AXVN01000023_gene1804	1.63e-197	561.0	COG3584@1|root,COG3883@1|root,COG3584@2|Bacteria,COG3883@2|Bacteria,1UI15@1239|Firmicutes,25EA3@186801|Clostridia,3XZ75@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	-
NHEHCBFB_00094	1121115.AXVN01000023_gene1805	5.69e-170	474.0	COG1180@1|root,COG1180@2|Bacteria,1V1GP@1239|Firmicutes,24G76@186801|Clostridia,3XZK7@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NHEHCBFB_00095	1121115.AXVN01000023_gene1806	2.13e-255	699.0	2BZEU@1|root,30VT8@2|Bacteria,1V54M@1239|Firmicutes,24SSI@186801|Clostridia,3XZVW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00097	1121115.AXVN01000023_gene1807	1.44e-111	321.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,3XZVE@572511|Blautia	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
NHEHCBFB_00098	1121115.AXVN01000023_gene1808	0.0	892.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZ7Q@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_00099	1121115.AXVN01000023_gene1809	4.46e-258	707.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,3XZ13@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NHEHCBFB_00100	1121115.AXVN01000023_gene1810	0.0	1044.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3XZM7@572511|Blautia	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
NHEHCBFB_00101	1121115.AXVN01000122_gene2850	3.98e-72	217.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3Y02F@572511|Blautia	186801|Clostridia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
NHEHCBFB_00102	1121115.AXVN01000122_gene2851	2.17e-140	396.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3XZEE@572511|Blautia	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
NHEHCBFB_00103	457412.RSAG_02634	4.47e-258	708.0	COG1609@1|root,COG1609@2|Bacteria,1UYY5@1239|Firmicutes,24C8C@186801|Clostridia,3WIXJ@541000|Ruminococcaceae	186801|Clostridia	K	Periplasmic binding protein domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NHEHCBFB_00104	1121115.AXVN01000122_gene2853	8.69e-149	419.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,3XYWX@572511|Blautia	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
NHEHCBFB_00105	1121115.AXVN01000122_gene2854	5.5e-201	556.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZ3S@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
NHEHCBFB_00106	1121115.AXVN01000122_gene2855	1.61e-221	611.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,3XZRN@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
NHEHCBFB_00107	1121115.AXVN01000122_gene2856	1.81e-127	362.0	2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,24JCA@186801|Clostridia,3Y027@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1256
NHEHCBFB_00108	1121115.AXVN01000122_gene2857	3.27e-284	781.0	COG1388@1|root,COG1388@2|Bacteria,1V4FJ@1239|Firmicutes,24IPI@186801|Clostridia,3XZF7@572511|Blautia	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
NHEHCBFB_00109	1121115.AXVN01000122_gene2858	3.79e-279	766.0	2C3W5@1|root,2ZBIU@2|Bacteria,1UZRE@1239|Firmicutes,24BHB@186801|Clostridia,3XYH0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00110	457412.RSAG_02627	4.61e-156	439.0	2DMJ6@1|root,32RY3@2|Bacteria,1VBBI@1239|Firmicutes,257PM@186801|Clostridia,3WK8E@541000|Ruminococcaceae	186801|Clostridia	S	Colicin V production protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
NHEHCBFB_00111	457412.RSAG_03003	0.0	1040.0	29WVX@1|root,30IHI@2|Bacteria,1UPZS@1239|Firmicutes,257M6@186801|Clostridia,3WIT7@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00112	1121115.AXVN01000005_gene2263	3.89e-304	833.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3XYK2@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_00113	1121115.AXVN01000005_gene2262	1.53e-161	454.0	2DPYM@1|root,333Z5@2|Bacteria,1VFMY@1239|Firmicutes,24SP4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00114	1121115.AXVN01000005_gene2261	1.4e-241	664.0	COG1835@1|root,COG1835@2|Bacteria,1VIE2@1239|Firmicutes,24SHJ@186801|Clostridia	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NHEHCBFB_00115	1121115.AXVN01000005_gene2260	1.71e-190	527.0	COG1278@1|root,COG1278@2|Bacteria,1URQI@1239|Firmicutes,259M3@186801|Clostridia,3Y0QB@572511|Blautia	186801|Clostridia	K	Domain of unknown function (DUF3825)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3825
NHEHCBFB_00116	1121115.AXVN01000005_gene2259	1.02e-291	796.0	COG0500@1|root,COG0789@1|root,COG0789@2|Bacteria,COG2226@2|Bacteria,1TSDZ@1239|Firmicutes,248EY@186801|Clostridia,3Y1FI@572511|Blautia	186801|Clostridia	KQ	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_11,Methyltransf_25,Methyltransf_31
NHEHCBFB_00117	1121115.AXVN01000005_gene2258	3.65e-220	606.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,3XZAG@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
NHEHCBFB_00118	457412.RSAG_03011	1.63e-261	714.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
NHEHCBFB_00119	1121115.AXVN01000005_gene2256	1.02e-229	632.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,3XZI0@572511|Blautia	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
NHEHCBFB_00120	1410612.JNKO01000012_gene518	2.06e-164	485.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,2PS1C@265975|Oribacterium	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
NHEHCBFB_00121	457412.RSAG_03013	0.0	1094.0	COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,248AI@186801|Clostridia,3WN2E@541000|Ruminococcaceae	186801|Clostridia	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
NHEHCBFB_00122	457412.RSAG_03014	1.29e-233	643.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,3WIYW@541000|Ruminococcaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
NHEHCBFB_00123	1121115.AXVN01000005_gene2253	3.67e-149	419.0	COG1102@1|root,COG1102@2|Bacteria,1V5TS@1239|Firmicutes,24HRW@186801|Clostridia	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NHEHCBFB_00124	1121115.AXVN01000005_gene2252	9.73e-179	498.0	COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,249GD@186801|Clostridia,3Y0Y6@572511|Blautia	186801|Clostridia	S	LamB/YcsF family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
NHEHCBFB_00125	457412.RSAG_03018	2.22e-311	850.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,3WHD3@541000|Ruminococcaceae	186801|Clostridia	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
NHEHCBFB_00126	457412.RSAG_03019	1.17e-95	279.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,3WJAY@541000|Ruminococcaceae	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
NHEHCBFB_00127	457412.RSAG_03020	1.25e-241	664.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,2485K@186801|Clostridia,3WMXD@541000|Ruminococcaceae	186801|Clostridia	E	Pfam:AHS2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
NHEHCBFB_00128	457412.RSAG_03021	2.93e-177	493.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,24A35@186801|Clostridia,3WNN6@541000|Ruminococcaceae	186801|Clostridia	E	Pfam:AHS1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
NHEHCBFB_00129	457412.RSAG_03022	7.09e-258	710.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,248DM@186801|Clostridia,3WGJU@541000|Ruminococcaceae	186801|Clostridia	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
NHEHCBFB_00130	1121115.AXVN01000005_gene2246	0.0	963.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3XZ0N@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
NHEHCBFB_00131	1121115.AXVN01000005_gene2245	4.31e-179	498.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,3XYR9@572511|Blautia	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
NHEHCBFB_00132	457412.RSAG_03025	2.37e-218	602.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,3WGJ2@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
NHEHCBFB_00133	457412.RSAG_03026	0.0	1920.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25Q4H@186801|Clostridia,3WH43@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
NHEHCBFB_00134	457412.RSAG_03027	1.11e-126	361.0	2C0IG@1|root,324G4@2|Bacteria,1UQRN@1239|Firmicutes,258HV@186801|Clostridia,3WMTD@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00135	457412.RSAG_03028	3.55e-282	769.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,3WHCZ@541000|Ruminococcaceae	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
NHEHCBFB_00136	457412.RSAG_03029	0.0	941.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,3WGAA@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
NHEHCBFB_00137	1121115.AXVN01000005_gene2239	1.68e-141	398.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,3XZW0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	KatE	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00138	1121115.AXVN01000005_gene2238	0.0	1303.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,3XZJM@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase
NHEHCBFB_00139	1121115.AXVN01000005_gene2237	5.95e-191	528.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,3XYR4@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 9.98	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
NHEHCBFB_00140	1121115.AXVN01000005_gene2236	1.2e-83	247.0	2E3QR@1|root,32YNK@2|Bacteria,1VENX@1239|Firmicutes,24QVR@186801|Clostridia,3Y0KX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
NHEHCBFB_00141	1121115.AXVN01000005_gene2235	0.0	1722.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia,3Y17B@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NHEHCBFB_00142	1121115.AXVN01000005_gene2234	1.23e-188	523.0	28P0Q@1|root,2ZBX8@2|Bacteria,1V22P@1239|Firmicutes,248XV@186801|Clostridia,3XZCT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00143	1121115.AXVN01000005_gene2233	3.77e-291	794.0	COG3007@1|root,COG3007@2|Bacteria,1TWIF@1239|Firmicutes,249TW@186801|Clostridia,3XZSQ@572511|Blautia	186801|Clostridia	I	Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA)	fabV	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
NHEHCBFB_00144	1121115.AXVN01000005_gene2232	9.99e-120	342.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24GHG@186801|Clostridia,3XZTE@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
NHEHCBFB_00145	1121115.AXVN01000005_gene2231	2.42e-114	327.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,3XZW3@572511|Blautia	186801|Clostridia	C	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NHEHCBFB_00146	457412.RSAG_03038	0.0	1357.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
NHEHCBFB_00147	1121115.AXVN01000005_gene2229	8.72e-53	166.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3Y0EQ@572511|Blautia	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
NHEHCBFB_00148	1121115.AXVN01000005_gene2228	1.04e-217	600.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,3XZMT@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
NHEHCBFB_00149	457412.RSAG_03041	2.64e-211	583.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,3WH28@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
NHEHCBFB_00150	457412.RSAG_03042	1.34e-233	642.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WGKS@541000|Ruminococcaceae	186801|Clostridia	S	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
NHEHCBFB_00151	1121115.AXVN01000005_gene2225	4.61e-84	248.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3Y0A9@572511|Blautia	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
NHEHCBFB_00152	457412.RSAG_03044	0.0	1516.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,3WHTD@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
NHEHCBFB_00153	457412.RSAG_03045	4.9e-64	195.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia,3WM5W@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
NHEHCBFB_00154	1121115.AXVN01000005_gene2222	4.94e-58	179.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,3Y0GX@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
NHEHCBFB_00155	1121115.AXVN01000005_gene2221	1.78e-254	702.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3XZH6@572511|Blautia	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
NHEHCBFB_00156	1121115.AXVN01000005_gene2220	9.83e-106	305.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,3Y03N@572511|Blautia	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
NHEHCBFB_00157	1121115.AXVN01000005_gene2219	0.0	1441.0	COG0188@1|root,COG0188@2|Bacteria,1TPNX@1239|Firmicutes,24ADK@186801|Clostridia,3XZJ2@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	gyrA_1	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
NHEHCBFB_00158	457412.RSAG_03050	0.0	1285.0	COG0187@1|root,COG0187@2|Bacteria,1TRSZ@1239|Firmicutes,247ZY@186801|Clostridia,3WIA4@541000|Ruminococcaceae	186801|Clostridia	L	TopoisomeraseII	parE	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
NHEHCBFB_00160	1121115.AXVN01000005_gene2217	0.0	1415.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3XZ98@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
NHEHCBFB_00161	457412.RSAG_03063	0.0	986.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,3WI8N@541000|Ruminococcaceae	186801|Clostridia	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
NHEHCBFB_00162	457412.RSAG_03064	0.0	874.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,3WH9K@541000|Ruminococcaceae	186801|Clostridia	S	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
NHEHCBFB_00163	457412.RSAG_03065	1.42e-270	740.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,3WI13@541000|Ruminococcaceae	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
NHEHCBFB_00164	1121115.AXVN01000005_gene2213	1.66e-304	830.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3XYMS@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
NHEHCBFB_00165	1121115.AXVN01000005_gene2212	1.89e-95	277.0	COG4905@1|root,COG4905@2|Bacteria,1VAQJ@1239|Firmicutes,24K5I@186801|Clostridia,3Y0E6@572511|Blautia	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NHEHCBFB_00166	457412.RSAG_03068	1.94e-215	595.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WG83@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
NHEHCBFB_00167	1121115.AXVN01000005_gene2210	1.09e-100	291.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia,3XZVS@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
NHEHCBFB_00168	457412.RSAG_03070	0.0	1099.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia,3WI74@541000|Ruminococcaceae	186801|Clostridia	F	Phosphoribulokinase uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
NHEHCBFB_00169	457412.RSAG_03071	1.1e-186	518.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,3WJ9H@541000|Ruminococcaceae	186801|Clostridia	S	dinuclear metal center protein, YbgI	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
NHEHCBFB_00170	1121115.AXVN01000005_gene2207	1.23e-166	466.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,3XZUP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
NHEHCBFB_00171	1121115.AXVN01000005_gene2206	2.44e-234	649.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3XZ4I@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
NHEHCBFB_00172	1121115.AXVN01000005_gene2205	0.0	1175.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3XYMV@572511|Blautia	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
NHEHCBFB_00173	1121115.AXVN01000005_gene2204	8.47e-240	659.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia,3XYN7@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
NHEHCBFB_00175	1121115.AXVN01000073_gene2025	5.17e-310	844.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,3XZDX@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
NHEHCBFB_00176	457412.RSAG_03077	2.43e-29	105.0	COG0163@1|root,COG0163@2|Bacteria	2|Bacteria	H	prenyltransferase activity	ubiX	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
NHEHCBFB_00177	1121115.AXVN01000073_gene2023	0.0	1129.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NHEHCBFB_00178	457412.RSAG_03079	3.53e-159	446.0	2EX9H@1|root,33QK7@2|Bacteria,1VRP0@1239|Firmicutes,24YQ9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00179	1121115.AXVN01000073_gene2021	1.09e-164	461.0	COG1811@1|root,COG1811@2|Bacteria,1TQWV@1239|Firmicutes,25CHE@186801|Clostridia,3Y0MN@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
NHEHCBFB_00180	457412.RSAG_03081	1.46e-300	821.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WGQW@541000|Ruminococcaceae	186801|Clostridia	M	Metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
NHEHCBFB_00181	457412.RSAG_03082	9.65e-271	741.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WGCN@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
NHEHCBFB_00182	457412.RSAG_03083	5.78e-175	489.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,3WH2Z@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score 10.00	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
NHEHCBFB_00183	1121115.AXVN01000073_gene2016	7.75e-170	474.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,3XYZ5@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
NHEHCBFB_00184	1121115.AXVN01000073_gene2015	1.12e-116	335.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3XZAV@572511|Blautia	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
NHEHCBFB_00185	1121115.AXVN01000073_gene2014	1.62e-160	450.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,3XZ3X@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NHEHCBFB_00186	1121115.AXVN01000073_gene2013	1.61e-177	503.0	2EY3W@1|root,33RCQ@2|Bacteria,1VU3P@1239|Firmicutes,24XPJ@186801|Clostridia,3XZZ1@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00187	1121115.AXVN01000073_gene2011	4.66e-105	303.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3XZU0@572511|Blautia	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
NHEHCBFB_00188	1121115.AXVN01000073_gene2010	0.0	1442.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3XZBT@572511|Blautia	186801|Clostridia	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
NHEHCBFB_00189	457412.RSAG_03091	1.24e-43	142.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes,25N7Y@186801|Clostridia,3WM7P@541000|Ruminococcaceae	186801|Clostridia	U	Preprotein translocase SecG subunit	-	-	-	-	-	-	-	-	-	-	-	-	SecG
NHEHCBFB_00190	1121115.AXVN01000073_gene2008	0.0	865.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3XYIB@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
NHEHCBFB_00191	457412.RSAG_03435	3.03e-188	524.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia,3WI2P@541000|Ruminococcaceae	186801|Clostridia	G	Delta-lactam-biosynthetic de-N-acetylase	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
NHEHCBFB_00192	457412.RSAG_03436	2.05e-199	556.0	COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,249IK@186801|Clostridia,3WMX0@541000|Ruminococcaceae	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NHEHCBFB_00193	1121115.AXVN01000161_gene1323	1.32e-169	474.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia	186801|Clostridia	E	abc transporter atp-binding protein	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
NHEHCBFB_00194	1121115.AXVN01000161_gene1324	1.05e-153	432.0	COG0765@1|root,COG0765@2|Bacteria,1TR7R@1239|Firmicutes,24823@186801|Clostridia	186801|Clostridia	P	acid ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
NHEHCBFB_00195	1121115.AXVN01000161_gene1325	4.62e-145	410.0	COG0765@1|root,COG0765@2|Bacteria,1TRU3@1239|Firmicutes,249IY@186801|Clostridia	186801|Clostridia	P	ABC transporter, permease protein	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
NHEHCBFB_00196	1121115.AXVN01000161_gene1326	3.47e-154	432.0	COG2755@1|root,COG2755@2|Bacteria,1V49F@1239|Firmicutes,24D1K@186801|Clostridia,3Y0I8@572511|Blautia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NHEHCBFB_00197	1121115.AXVN01000153_gene3985	6.75e-101	292.0	COG3610@1|root,COG3610@2|Bacteria,1UVFM@1239|Firmicutes,257UX@186801|Clostridia,3Y1J9@572511|Blautia	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
NHEHCBFB_00198	457412.RSAG_03448	9.34e-176	490.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia,3WJYI@541000|Ruminococcaceae	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
NHEHCBFB_00199	457412.RSAG_03441	5.3e-166	466.0	COG2207@1|root,COG2207@2|Bacteria,1U23Q@1239|Firmicutes,25BMJ@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NHEHCBFB_00200	1121115.AXVN01000186_gene2049	0.0	1392.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3XYUA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NHEHCBFB_00201	515620.EUBELI_01891	5.71e-48	166.0	COG0025@1|root,COG0025@2|Bacteria,1UHUI@1239|Firmicutes,25E2Y@186801|Clostridia	186801|Clostridia	P	Transporter, CPA2 family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
NHEHCBFB_00202	1121115.AXVN01000004_gene2002	0.0	952.0	2EXAA@1|root,33QKY@2|Bacteria,1VU9D@1239|Firmicutes,24Y4F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00203	1121115.AXVN01000004_gene2003	8.14e-98	286.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,3Y0EF@572511|Blautia	186801|Clostridia	K	COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NHEHCBFB_00205	1230342.CTM_07796	7.91e-85	271.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,36GDC@31979|Clostridiaceae	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
NHEHCBFB_00206	386415.NT01CX_0966	8.36e-112	331.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,36DX1@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NHEHCBFB_00207	904296.HMPREF9124_0174	2.3e-100	301.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,2PR0U@265975|Oribacterium	186801|Clostridia	P	ABC transporter permease protein	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NHEHCBFB_00208	573061.Clocel_4249	3.55e-25	108.0	COG0491@1|root,COG0491@2|Bacteria,1TX4N@1239|Firmicutes,24A0N@186801|Clostridia,36KSI@31979|Clostridiaceae	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd,Lactamase_B
NHEHCBFB_00209	1121115.AXVN01000014_gene1231	1.17e-303	830.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,258AG@186801|Clostridia,3Y0AF@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
NHEHCBFB_00210	457412.RSAG_01682	1.06e-105	305.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,3WHNP@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
NHEHCBFB_00211	457412.RSAG_01681	1.91e-108	312.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,3WHNP@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
NHEHCBFB_00212	1121115.AXVN01000014_gene1239	5.87e-228	632.0	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,3XYJ1@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
NHEHCBFB_00213	457412.RSAG_01679	6.26e-213	587.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia,3WHMV@541000|Ruminococcaceae	186801|Clostridia	L	NADH pyrophosphatase zinc ribbon domain	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
NHEHCBFB_00214	1121115.AXVN01000014_gene1241	2.23e-283	773.0	COG2055@1|root,COG2055@2|Bacteria,1TR0Z@1239|Firmicutes,247W5@186801|Clostridia,3Y0AK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	mdh	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
NHEHCBFB_00215	457412.RSAG_01677	4.05e-93	273.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,3WKS1@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
NHEHCBFB_00216	1121115.AXVN01000014_gene1243	1.09e-224	620.0	2BADS@1|root,323U8@2|Bacteria,1VTZ8@1239|Firmicutes,24ZP1@186801|Clostridia,3Y1JU@572511|Blautia	186801|Clostridia	S	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00217	457412.RSAG_01675	2.24e-210	582.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	bla1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
NHEHCBFB_00218	1121115.AXVN01000014_gene1245	2.4e-268	732.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia,3Y1E6@572511|Blautia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NHEHCBFB_00219	1121115.AXVN01000014_gene1246	2.32e-194	539.0	COG1410@1|root,COG1410@2|Bacteria,1UV7K@1239|Firmicutes,25CEH@186801|Clostridia,3Y0ZA@572511|Blautia	186801|Clostridia	E	Pterin binding enzyme	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
NHEHCBFB_00220	1121115.AXVN01000014_gene1247	5.21e-138	391.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,3Y0XR@572511|Blautia	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
NHEHCBFB_00221	1121115.AXVN01000014_gene1248	0.0	1124.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,3Y14F@572511|Blautia	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
NHEHCBFB_00222	457412.RSAG_01670	2.61e-133	377.0	COG5423@1|root,COG5423@2|Bacteria,1V8Y4@1239|Firmicutes,24EAF@186801|Clostridia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NHEHCBFB_00223	1121115.AXVN01000164_gene904	1.98e-142	402.0	COG5012@1|root,COG5012@2|Bacteria,1VSJU@1239|Firmicutes,24XK2@186801|Clostridia,3Y145@572511|Blautia	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
NHEHCBFB_00224	457412.RSAG_01667	0.0	1002.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,3WM6D@541000|Ruminococcaceae	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
NHEHCBFB_00225	1121115.AXVN01000147_gene3487	1.51e-126	361.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,3Y039@572511|Blautia	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
NHEHCBFB_00226	1121115.AXVN01000147_gene3488	1.03e-265	728.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3XYJ0@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NHEHCBFB_00227	457412.RSAG_01664	3.2e-248	684.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3WGWG@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NHEHCBFB_00228	1121115.AXVN01000147_gene3490	0.0	924.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,3XZJ0@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
NHEHCBFB_00229	1121115.AXVN01000147_gene3491	3.54e-185	514.0	COG0463@1|root,COG0463@2|Bacteria,1TSPS@1239|Firmicutes,25FHJ@186801|Clostridia,3Y1C1@572511|Blautia	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NHEHCBFB_00230	457412.RSAG_03495	1.7e-314	858.0	COG3594@1|root,COG3594@2|Bacteria	2|Bacteria	G	nodulation	-	-	-	ko:K13663	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
NHEHCBFB_00231	457412.RSAG_01661	9.56e-317	862.0	COG0615@1|root,COG0673@1|root,COG0615@2|Bacteria,COG0673@2|Bacteria,1V3KY@1239|Firmicutes,24BKY@186801|Clostridia,3WIHC@541000|Ruminococcaceae	186801|Clostridia	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,GFO_IDH_MocA
NHEHCBFB_00232	457412.RSAG_01660	0.0	1548.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,3WKER@541000|Ruminococcaceae	186801|Clostridia	M	LicD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
NHEHCBFB_00233	457412.RSAG_01659	1.99e-282	771.0	COG3475@1|root,COG3475@2|Bacteria	2|Bacteria	M	LICD family	licD	-	-	ko:K02011,ko:K07271,ko:K19872	ko00515,ko01100,ko02010,map00515,map01100,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko04131	3.A.1.10	-	-	LicD
NHEHCBFB_00234	1121115.AXVN01000121_gene2848	0.0	1152.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3XZCN@572511|Blautia	186801|Clostridia	H	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NHEHCBFB_00235	1121115.AXVN01000121_gene2849	1.98e-177	494.0	COG1028@1|root,COG1028@2|Bacteria,1V2KA@1239|Firmicutes,24GZZ@186801|Clostridia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NHEHCBFB_00236	1121115.AXVN01000018_gene13	7.29e-46	147.0	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,24QK0@186801|Clostridia,3Y0JI@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
NHEHCBFB_00237	1121115.AXVN01000018_gene14	1.44e-38	129.0	COG0690@1|root,COG0690@2|Bacteria,1VH7Y@1239|Firmicutes,24RJ1@186801|Clostridia,3Y0SS@572511|Blautia	186801|Clostridia	U	SecE/Sec61-gamma subunits of protein translocation complex	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
NHEHCBFB_00238	1121115.AXVN01000018_gene15	3.32e-119	340.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,3XZ8Y@572511|Blautia	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
NHEHCBFB_00239	1121115.AXVN01000018_gene16	3.14e-89	262.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3XZUC@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
NHEHCBFB_00240	1121115.AXVN01000018_gene17	3.53e-159	446.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
NHEHCBFB_00241	97139.C824_02909	5.02e-139	395.0	COG0235@1|root,COG0235@2|Bacteria,1UYB8@1239|Firmicutes,25N0E@186801|Clostridia,36T1N@31979|Clostridiaceae	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
NHEHCBFB_00242	1232453.BAIF02000033_gene2664	3.74e-173	496.0	COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,24AE3@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_IclR,ROK
NHEHCBFB_00243	97139.C824_02911	2.12e-203	579.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,36FYV@31979|Clostridiaceae	186801|Clostridia	G	Carbohydrate kinase	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
NHEHCBFB_00244	97139.C824_02912	5.48e-254	704.0	COG1653@1|root,COG1653@2|Bacteria,1TS2P@1239|Firmicutes,24EIW@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_00245	97139.C824_02913	3.29e-170	481.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,36H1Y@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17316	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
NHEHCBFB_00246	97139.C824_02914	1.91e-117	345.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia,36GNX@31979|Clostridiaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NHEHCBFB_00247	97139.C824_02915	1.4e-114	340.0	COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,36E0T@31979|Clostridiaceae	186801|Clostridia	G	Dihydroxyacetone kinase DhaK, subunit	dhaK	-	2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01012,R01059	RC00002,RC00015,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1,Dak2
NHEHCBFB_00248	97139.C824_02916	1.48e-76	236.0	COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,24FUX@186801|Clostridia,36I2G@31979|Clostridiaceae	186801|Clostridia	S	Dihydroxyacetone kinase	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
NHEHCBFB_00249	97139.C824_02917	4.43e-161	456.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,24AUB@186801|Clostridia,36JWU@31979|Clostridiaceae	186801|Clostridia	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
NHEHCBFB_00250	457412.RSAG_01651	9.84e-235	646.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,24AQE@186801|Clostridia,3WGMZ@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
NHEHCBFB_00251	1121115.AXVN01000018_gene19	3.42e-58	182.0	2EUJQ@1|root,33N1P@2|Bacteria,1VMKN@1239|Firmicutes,250D1@186801|Clostridia,3Y0U5@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00252	457412.RSAG_01649	8.68e-129	365.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3WGYN@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
NHEHCBFB_00253	457412.RSAG_01648	3.06e-94	275.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,3WKYJ@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
NHEHCBFB_00254	1121115.AXVN01000018_gene36	0.0	1316.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3XYH1@572511|Blautia	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
NHEHCBFB_00255	457412.RSAG_01645	1.44e-109	315.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,3WJ9J@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
NHEHCBFB_00256	457412.RSAG_01644	4.6e-108	311.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,3WHT9@541000|Ruminococcaceae	186801|Clostridia	H	Molybdenum cofactor synthesis domain protein	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
NHEHCBFB_00257	457412.RSAG_01643	1.82e-102	296.0	COG2258@1|root,COG2258@2|Bacteria,1UIYW@1239|Firmicutes,25FCC@186801|Clostridia	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
NHEHCBFB_00258	1121115.AXVN01000018_gene40	9.39e-183	508.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3XZFC@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
NHEHCBFB_00259	457412.RSAG_01641	0.0	907.0	COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,24950@186801|Clostridia,3WIMU@541000|Ruminococcaceae	186801|Clostridia	M	Capsule synthesis protein	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
NHEHCBFB_00260	1121115.AXVN01000018_gene42	3.05e-96	281.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,24HTB@186801|Clostridia,3Y09U@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
NHEHCBFB_00261	1121115.AXVN01000018_gene43	5.75e-266	728.0	COG0503@1|root,COG0503@2|Bacteria,1UZSF@1239|Firmicutes,24FUM@186801|Clostridia,3Y1E0@572511|Blautia	186801|Clostridia	F	Phosphoribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PRTase_2,TRSP
NHEHCBFB_00262	457412.RSAG_01638	1.1e-254	698.0	COG1358@1|root,COG1358@2|Bacteria,1TP5Y@1239|Firmicutes,2487J@186801|Clostridia,3WH6S@541000|Ruminococcaceae	186801|Clostridia	J	PELOTA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PELOTA_1,PRTase_1,PRTase_2,TRSP
NHEHCBFB_00263	1121115.AXVN01000018_gene45	3.16e-232	639.0	COG2301@1|root,COG2301@2|Bacteria,1TSF2@1239|Firmicutes,249TC@186801|Clostridia,3Y1G9@572511|Blautia	186801|Clostridia	G	C-C_Bond_Lyase of the TIM-Barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	C-C_Bond_Lyase
NHEHCBFB_00264	1121115.AXVN01000018_gene46	0.0	1521.0	2BVVP@1|root,2Z9CR@2|Bacteria,1TRYC@1239|Firmicutes,2487Q@186801|Clostridia,3Y1D8@572511|Blautia	186801|Clostridia	S	Putative component of 'biosynthetic module'	-	-	-	-	-	-	-	-	-	-	-	-	YceG_bac
NHEHCBFB_00265	1121115.AXVN01000018_gene47	1.02e-258	711.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3Y1EX@572511|Blautia	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
NHEHCBFB_00266	1121115.AXVN01000018_gene48	8.14e-136	384.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,3Y15Q@572511|Blautia	186801|Clostridia	T	TerD domain	terD_2	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
NHEHCBFB_00267	457412.RSAG_01633	3.1e-137	388.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,3WI1I@541000|Ruminococcaceae	186801|Clostridia	T	TerD domain	-	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
NHEHCBFB_00268	1121115.AXVN01000018_gene50	1.78e-145	409.0	COG2310@1|root,COG2310@2|Bacteria,1TR98@1239|Firmicutes,24FZM@186801|Clostridia,3Y13G@572511|Blautia	186801|Clostridia	T	TerD domain	yceC	-	-	-	-	-	-	-	-	-	-	-	TerD
NHEHCBFB_00269	457412.RSAG_01630	0.0	1599.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3WHET@541000|Ruminococcaceae	186801|Clostridia	P	Calcium-translocating P-type ATPase, PMCA-type	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
NHEHCBFB_00270	1121115.AXVN01000018_gene52	5.92e-176	491.0	COG0561@1|root,COG0561@2|Bacteria,1V24C@1239|Firmicutes,24HGT@186801|Clostridia,3Y1I1@572511|Blautia	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,S6PP
NHEHCBFB_00271	1121115.AXVN01000018_gene53	0.0	1154.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia,3XYKE@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
NHEHCBFB_00272	457412.RSAG_01628	1.33e-120	350.0	COG0791@1|root,COG0791@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,3WRJN@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
NHEHCBFB_00273	1121115.AXVN01000018_gene55	1.75e-133	379.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,3XYVE@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
NHEHCBFB_00274	1121115.AXVN01000018_gene56	0.0	911.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,3XZA3@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	ntpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
NHEHCBFB_00275	457412.RSAG_01625	0.0	1171.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,3WGBK@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
NHEHCBFB_00276	1121115.AXVN01000018_gene58	6.2e-129	367.0	COG1390@1|root,COG1390@2|Bacteria,1V7UJ@1239|Firmicutes,24ICM@186801|Clostridia,3Y0B1@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
NHEHCBFB_00277	1121115.AXVN01000018_gene59	5.62e-69	208.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,3Y07R@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
NHEHCBFB_00278	1121115.AXVN01000018_gene60	1.37e-84	251.0	COG0636@1|root,COG0636@2|Bacteria,1VAGE@1239|Firmicutes,24RB6@186801|Clostridia,3Y0BA@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
NHEHCBFB_00279	1121115.AXVN01000018_gene61	0.0	1267.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,3XZ9K@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
NHEHCBFB_00280	457412.RSAG_01620	5.85e-253	693.0	COG1527@1|root,COG1527@2|Bacteria,1U1QE@1239|Firmicutes,24A4E@186801|Clostridia,3WGJ9@541000|Ruminococcaceae	186801|Clostridia	C	Archaeal vacuolar-type H -ATPase subunit C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
NHEHCBFB_00281	1121115.AXVN01000018_gene63	1.48e-28	106.0	2EC7P@1|root,33668@2|Bacteria,1VHK0@1239|Firmicutes,24R0C@186801|Clostridia,3Y0UW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00282	1121115.AXVN01000018_gene64	2.15e-160	449.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia,3XZ71@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
NHEHCBFB_00284	457412.RSAG_01617	0.0	907.0	COG1502@1|root,COG1502@2|Bacteria,1TSN8@1239|Firmicutes,249G7@186801|Clostridia,3WHXK@541000|Ruminococcaceae	186801|Clostridia	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
NHEHCBFB_00285	1121115.AXVN01000018_gene67	0.0	1660.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3XZ46@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF5110)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,Glyco_hydro_31
NHEHCBFB_00286	457412.RSAG_01615	0.0	1055.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3WGXK@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
NHEHCBFB_00287	938289.CAJN020000001_gene1164	8.42e-115	329.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,24HXG@186801|Clostridia,26B2Y@186813|unclassified Clostridiales	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NHEHCBFB_00288	428125.CLOLEP_03211	6.81e-34	116.0	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24R3P@186801|Clostridia,3WM8N@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00289	938289.CAJN020000001_gene1165	9.56e-267	729.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,2689P@186813|unclassified Clostridiales	186801|Clostridia	L	Site-specific recombinase, phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NHEHCBFB_00290	411460.RUMTOR_02161	1.43e-64	197.0	2AQJ5@1|root,31FRY@2|Bacteria,1V6TG@1239|Firmicutes,25MZ5@186801|Clostridia,3Y0P8@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00291	478749.BRYFOR_06470	4.53e-245	676.0	COG3598@1|root,COG3598@2|Bacteria,1TU5N@1239|Firmicutes,247KK@186801|Clostridia	186801|Clostridia	L	COG NOG19743 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,PriCT_1,Prim-Pol
NHEHCBFB_00292	428125.CLOLEP_03219	6.18e-201	565.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,3WHRE@541000|Ruminococcaceae	186801|Clostridia	M	plasmid recombination	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
NHEHCBFB_00293	938289.CAJN020000001_gene1169	1.3e-87	257.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes,24IHH@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NHEHCBFB_00294	1280696.ATVY01000024_gene1018	4.92e-259	723.0	COG0488@1|root,COG0488@2|Bacteria,1TU6J@1239|Firmicutes,24APJ@186801|Clostridia,4BX94@830|Butyrivibrio	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NHEHCBFB_00295	679937.Bcop_0088	1.9e-72	222.0	COG0617@1|root,COG0617@2|Bacteria,4NZY6@976|Bacteroidetes,2FQ7N@200643|Bacteroidia,4ARIS@815|Bacteroidaceae	976|Bacteroidetes	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	Aminoglyc_resit
NHEHCBFB_00296	471875.RUMLAC_01450	4.1e-142	410.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24EQM@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NHEHCBFB_00304	1121115.AXVN01000115_gene2458	3.42e-194	539.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia,3Y01U@572511|Blautia	186801|Clostridia	D	COG COG2385 Sporulation protein and related proteins	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
NHEHCBFB_00305	1121115.AXVN01000115_gene2457	9.42e-202	560.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia,3Y09E@572511|Blautia	186801|Clostridia	M	COG COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
NHEHCBFB_00306	1121115.AXVN01000115_gene2456	2.06e-233	642.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3XZ29@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	scrR	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NHEHCBFB_00307	1121115.AXVN01000115_gene2455	0.0	1217.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,3XZ3A@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	2.7.1.211	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
NHEHCBFB_00308	1121115.AXVN01000115_gene2454	0.0	1002.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3XZ5W@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	scrB	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
NHEHCBFB_00309	1121115.AXVN01000115_gene2453	6.18e-52	163.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,3Y0F0@572511|Blautia	186801|Clostridia	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
NHEHCBFB_00310	457412.RSAG_03203	1.79e-180	508.0	COG5263@1|root,COG5263@2|Bacteria,1UJWN@1239|Firmicutes,25FCE@186801|Clostridia,3WKY6@541000|Ruminococcaceae	186801|Clostridia	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
NHEHCBFB_00311	1121115.AXVN01000115_gene2450	3.1e-154	433.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,3XYGI@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
NHEHCBFB_00312	457412.RSAG_03201	2.71e-188	523.0	COG1192@1|root,COG1192@2|Bacteria,1UPGE@1239|Firmicutes,24A5R@186801|Clostridia,3WPYK@541000|Ruminococcaceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,HTH_3
NHEHCBFB_00313	1121115.AXVN01000031_gene322	1.58e-25	95.5	2CA4Q@1|root,349NE@2|Bacteria,1VYK2@1239|Firmicutes,253VZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00314	457412.RSAG_03199	1.06e-233	644.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia,3WK12@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NHEHCBFB_00315	1121115.AXVN01000031_gene330	0.0	1404.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3XYX5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pbg	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NHEHCBFB_00316	457412.RSAG_03197	0.0	2136.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WGFC@541000|Ruminococcaceae	186801|Clostridia	KL	SNF2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
NHEHCBFB_00317	457412.RSAG_03196	1.43e-123	352.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia,3WITH@541000|Ruminococcaceae	186801|Clostridia	K	stage V sporulation protein T	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
NHEHCBFB_00318	457412.RSAG_03195	5.4e-294	801.0	COG1408@1|root,COG1408@2|Bacteria,1TS43@1239|Firmicutes,248XA@186801|Clostridia,3WGZT@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NHEHCBFB_00319	457412.RSAG_03194	0.0	960.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,3WGKF@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
NHEHCBFB_00321	457412.RSAG_03193	0.0	896.0	COG2942@1|root,COG2942@2|Bacteria,1UQC2@1239|Firmicutes,24D2T@186801|Clostridia,3WQ2A@541000|Ruminococcaceae	186801|Clostridia	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
NHEHCBFB_00322	457412.RSAG_03192	2.89e-75	225.0	COG1115@1|root,COG1115@2|Bacteria,1VUZR@1239|Firmicutes,25092@186801|Clostridia	186801|Clostridia	E	Sodium:alanine symporter family	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ala_symp
NHEHCBFB_00323	457412.RSAG_03191	4.16e-150	422.0	COG0461@1|root,COG0461@2|Bacteria,1V23H@1239|Firmicutes,24FTS@186801|Clostridia,3WIVV@541000|Ruminococcaceae	186801|Clostridia	F	Orotate phosphoribosyltransferase	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
NHEHCBFB_00324	457412.RSAG_03190	2.91e-163	457.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3WHIA@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	phoP_1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_00325	457412.RSAG_03189	0.0	1730.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia,3WSJK@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NHEHCBFB_00326	1121115.AXVN01000031_gene344	1.15e-176	491.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia,3XZPR@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
NHEHCBFB_00327	1121115.AXVN01000031_gene345	1.65e-205	567.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia,3XZSF@572511|Blautia	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
NHEHCBFB_00328	1121115.AXVN01000031_gene346	9.87e-175	486.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,3XYMH@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
NHEHCBFB_00329	457412.RSAG_03185	1.08e-288	789.0	2EVYD@1|root,33PC0@2|Bacteria,1VUAR@1239|Firmicutes,24ZRA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00330	457412.RSAG_03184	2.73e-202	559.0	COG0657@1|root,COG0657@2|Bacteria,1TP1H@1239|Firmicutes,24D7F@186801|Clostridia,3WIPT@541000|Ruminococcaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
NHEHCBFB_00331	1121115.AXVN01000031_gene349	2.81e-194	539.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia,3XZD5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
NHEHCBFB_00332	457412.RSAG_03182	0.0	2281.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WGNQ@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
NHEHCBFB_00333	457412.RSAG_03181	1.65e-240	660.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3WH67@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
NHEHCBFB_00334	457412.RSAG_03180	0.0	892.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3WGPB@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NHEHCBFB_00335	457412.RSAG_03179	1.75e-148	418.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,3WJQ0@541000|Ruminococcaceae	186801|Clostridia	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NHEHCBFB_00336	457412.RSAG_03178	1.82e-179	500.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,3WIQ9@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
NHEHCBFB_00337	1121115.AXVN01000055_gene1900	4.78e-90	265.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia,3Y0IA@572511|Blautia	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
NHEHCBFB_00338	1121115.AXVN01000055_gene1901	1.41e-151	434.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3XZEQ@572511|Blautia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
NHEHCBFB_00339	1121115.AXVN01000055_gene1902	1.17e-245	674.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,3XYMZ@572511|Blautia	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
NHEHCBFB_00340	457412.RSAG_03174	1.84e-193	536.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WHDB@541000|Ruminococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
NHEHCBFB_00341	1121115.AXVN01000055_gene1904	2.46e-81	241.0	2CJXG@1|root,32SB0@2|Bacteria,1VAFJ@1239|Firmicutes,24MNI@186801|Clostridia,3Y06J@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00342	457412.RSAG_03172	1.03e-240	661.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,3WGDN@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
NHEHCBFB_00343	1121115.AXVN01000055_gene1906	1.94e-99	290.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,3XZTG@572511|Blautia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
NHEHCBFB_00344	457412.RSAG_03170	0.0	1318.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,3WH32@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
NHEHCBFB_00346	697329.Rumal_2401	9.12e-09	53.1	2A3KJ@1|root,30S3Q@2|Bacteria,1URZ5@1239|Firmicutes,259X2@186801|Clostridia,3WQUS@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00352	428125.CLOLEP_01733	2.21e-24	93.6	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,24RTS@186801|Clostridia,3WKN8@541000|Ruminococcaceae	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NHEHCBFB_00353	796945.HMPREF1145_1824	2.95e-214	601.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,2PRXW@265975|Oribacterium	186801|Clostridia	L	DNA binding domain of tn916 integrase	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_integrase
NHEHCBFB_00354	457412.RSAG_03169	0.0	1031.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,3WJCS@541000|Ruminococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NHEHCBFB_00355	1121115.AXVN01000055_gene1909	3.76e-244	670.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3XZ1P@572511|Blautia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NHEHCBFB_00356	1121115.AXVN01000055_gene1910	1.88e-220	607.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3Y14P@572511|Blautia	186801|Clostridia	E	Oligopeptide/dipeptide transporter, C-terminal region	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NHEHCBFB_00357	1121115.AXVN01000055_gene1911	2.25e-239	658.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XZP5@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NHEHCBFB_00358	1121115.AXVN01000055_gene1912	4.17e-204	565.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZFZ@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
NHEHCBFB_00359	1121115.AXVN01000055_gene1913	0.0	1112.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NHEHCBFB_00360	1121115.AXVN01000055_gene1914	1.05e-51	163.0	2CDIT@1|root,338T3@2|Bacteria,1VJ1M@1239|Firmicutes,24SF4@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
NHEHCBFB_00361	1121115.AXVN01000055_gene1915	1.52e-264	725.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,3XYVJ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7,Fer4_9
NHEHCBFB_00362	1121115.AXVN01000055_gene1916	3.45e-240	659.0	COG5018@1|root,COG5018@2|Bacteria,1TQJZ@1239|Firmicutes,24845@186801|Clostridia,3XYID@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
NHEHCBFB_00363	457412.RSAG_03160	3.99e-297	810.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WJ4Y@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NHEHCBFB_00364	457412.RSAG_03158	0.0	2165.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3WG9B@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
NHEHCBFB_00365	1121115.AXVN01000055_gene1920	0.0	1632.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3XZEY@572511|Blautia	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
NHEHCBFB_00366	457412.RSAG_01929	1.63e-83	260.0	COG5464@1|root,COG5464@2|Bacteria,1TUFY@1239|Firmicutes,259KT@186801|Clostridia,3WQBQ@541000|Ruminococcaceae	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00368	457412.RSAG_04544	0.0	1296.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CAP,G5,SLH,fn3
NHEHCBFB_00369	457412.RSAG_03137	1.5e-231	637.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,3WITB@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	lytC_3	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NHEHCBFB_00370	1121115.AXVN01000137_gene1823	8.4e-200	554.0	COG1047@1|root,COG1433@1|root,COG1047@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,24BUF@186801|Clostridia,3XYS8@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C,Nitro_FeMo-Co
NHEHCBFB_00371	1121115.AXVN01000137_gene1822	0.0	1009.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UVFQ@1239|Firmicutes,25KHE@186801|Clostridia,3Y1SM@572511|Blautia	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00373	457412.RSAG_03146	0.0	1517.0	COG3209@1|root,COG3209@2|Bacteria,1TRJ1@1239|Firmicutes,24AU6@186801|Clostridia,3WHF3@541000|Ruminococcaceae	186801|Clostridia	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,LRR_5,Transglut_core
NHEHCBFB_00374	411469.EUBHAL_01615	3.93e-168	478.0	COG5464@1|root,COG5464@2|Bacteria,1TS6U@1239|Firmicutes,24A2X@186801|Clostridia,25WK9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NHEHCBFB_00375	397287.C807_03981	3.2e-236	658.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,27JJ4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
NHEHCBFB_00376	1121115.AXVN01000016_gene3663	3.28e-166	464.0	COG3279@1|root,COG3279@2|Bacteria,1UHWR@1239|Firmicutes,25BYP@186801|Clostridia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NHEHCBFB_00377	411459.RUMOBE_02481	6.09e-174	485.0	COG3640@1|root,COG3640@2|Bacteria,1V308@1239|Firmicutes,24H11@186801|Clostridia	186801|Clostridia	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
NHEHCBFB_00379	411459.RUMOBE_02479	0.0	1157.0	COG4548@1|root,COG4548@2|Bacteria,1TS8V@1239|Firmicutes,249FH@186801|Clostridia,3XZDU@572511|Blautia	186801|Clostridia	P	NorD protein required for nitric oxide reductase (Nor) activity	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
NHEHCBFB_00380	411459.RUMOBE_02478	2.77e-221	610.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,249C6@186801|Clostridia,3XYS0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
NHEHCBFB_00381	411459.RUMOBE_02477	3.03e-182	507.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,3XYW4@572511|Blautia	186801|Clostridia	D	Anion-transporting ATPase	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	AAA_31,CbiA
NHEHCBFB_00382	411459.RUMOBE_02476	8.1e-153	429.0	COG1309@1|root,COG1309@2|Bacteria,1V6JC@1239|Firmicutes,24MPA@186801|Clostridia,3XZXC@572511|Blautia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NHEHCBFB_00383	1121115.AXVN01000016_gene3667	9.09e-142	400.0	2ES5J@1|root,33JQC@2|Bacteria,1VK71@1239|Firmicutes,24X6X@186801|Clostridia,3Y03E@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
NHEHCBFB_00384	1121115.AXVN01000016_gene3668	1.57e-94	276.0	COG1959@1|root,COG1959@2|Bacteria,1W6XJ@1239|Firmicutes,24SDU@186801|Clostridia,3Y0UG@572511|Blautia	186801|Clostridia	K	Winged helix-turn-helix transcription repressor, HrcA DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NHEHCBFB_00385	457412.RSAG_02522	8.5e-131	372.0	COG1102@1|root,COG1102@2|Bacteria,1UXGP@1239|Firmicutes,259Y0@186801|Clostridia,3WQJG@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NHEHCBFB_00386	1121115.AXVN01000163_gene908	1.38e-107	310.0	COG0454@1|root,COG0456@2|Bacteria,1V1VV@1239|Firmicutes,25CUX@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NHEHCBFB_00387	622312.ROSEINA2194_00550	3.63e-105	304.0	COG3467@1|root,COG3467@2|Bacteria,1VB7Q@1239|Firmicutes,24MUQ@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
NHEHCBFB_00388	457412.RSAG_02526	2.02e-137	388.0	COG1309@1|root,COG1309@2|Bacteria,1VGCX@1239|Firmicutes,24G4C@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NHEHCBFB_00389	457412.RSAG_02527	0.0	999.0	COG1022@1|root,COG1022@2|Bacteria,1V0YG@1239|Firmicutes,25E9H@186801|Clostridia,3WI3M@541000|Ruminococcaceae	186801|Clostridia	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
NHEHCBFB_00390	1121115.AXVN01000008_gene2658	8.84e-43	140.0	2DP4E@1|root,330GX@2|Bacteria,1VEZ7@1239|Firmicutes,24SE1@186801|Clostridia,3Y0WR@572511|Blautia	186801|Clostridia	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
NHEHCBFB_00391	1121115.AXVN01000008_gene2659	0.0	954.0	COG1020@1|root,COG1020@2|Bacteria,1TQP2@1239|Firmicutes,24AMK@186801|Clostridia,3Y0AJ@572511|Blautia	186801|Clostridia	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
NHEHCBFB_00392	457412.RSAG_02530	6.49e-245	671.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,3WK39@541000|Ruminococcaceae	186801|Clostridia	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	FSH1,Hydrolase_4,Peptidase_S9
NHEHCBFB_00393	411461.DORFOR_02067	2.7e-193	540.0	COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,24B85@186801|Clostridia,27VKR@189330|Dorea	186801|Clostridia	EG	COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NHEHCBFB_00394	1121115.AXVN01000008_gene2662	2.13e-40	133.0	COG4608@1|root,COG4608@2|Bacteria,1W0U9@1239|Firmicutes,252YQ@186801|Clostridia	186801|Clostridia	E	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00395	1121115.AXVN01000008_gene2663	1.01e-190	531.0	COG2510@1|root,COG2510@2|Bacteria,1V3VG@1239|Firmicutes,247SX@186801|Clostridia,3XZSJ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
NHEHCBFB_00396	457412.RSAG_02534	6.99e-155	434.0	COG2819@1|root,COG2819@2|Bacteria,1V1TT@1239|Firmicutes,24GDE@186801|Clostridia,3WIMM@541000|Ruminococcaceae	186801|Clostridia	S	hydrolase of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
NHEHCBFB_00397	457412.RSAG_02535	5.29e-300	819.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,3WHPN@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
NHEHCBFB_00398	457412.RSAG_02536	3.74e-302	826.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,3WHDK@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_00399	457412.RSAG_02537	2.08e-105	304.0	COG1846@1|root,COG1846@2|Bacteria,1V461@1239|Firmicutes,24HF7@186801|Clostridia,3WJ7N@541000|Ruminococcaceae	186801|Clostridia	K	Iron dependent repressor, N-terminal DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
NHEHCBFB_00400	1121115.AXVN01000008_gene2666	1.42e-198	553.0	COG0679@1|root,COG0679@2|Bacteria,1UYFH@1239|Firmicutes,24AI3@186801|Clostridia,3Y2CN@572511|Blautia	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NHEHCBFB_00401	1121115.AXVN01000008_gene2667	1.61e-119	342.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,24DSN@186801|Clostridia	186801|Clostridia	L	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
NHEHCBFB_00402	457412.RSAG_02540	4.16e-159	446.0	COG1122@1|root,COG1122@2|Bacteria,1V16T@1239|Firmicutes,25B0D@186801|Clostridia,3WJR6@541000|Ruminococcaceae	186801|Clostridia	P	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
NHEHCBFB_00403	457412.RSAG_02541	2.71e-118	340.0	COG0619@1|root,COG0619@2|Bacteria,1V7YC@1239|Firmicutes,25D5P@186801|Clostridia,3WSFY@541000|Ruminococcaceae	186801|Clostridia	P	Cobalt transport protein	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
NHEHCBFB_00404	1121115.AXVN01000008_gene2669	2.46e-60	192.0	COG0619@1|root,COG0619@2|Bacteria,1V7YC@1239|Firmicutes,25D5P@186801|Clostridia,3Y1C8@572511|Blautia	186801|Clostridia	P	Cobalt transport protein	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
NHEHCBFB_00405	457412.RSAG_02542	9e-230	634.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia,3WHIW@541000|Ruminococcaceae	186801|Clostridia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
NHEHCBFB_00406	1121115.AXVN01000008_gene2671	4.11e-174	486.0	COG4608@1|root,COG4608@2|Bacteria,1UV6D@1239|Firmicutes,25BCP@186801|Clostridia	186801|Clostridia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NHEHCBFB_00407	457412.RSAG_02544	1.63e-201	559.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,24B9N@186801|Clostridia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NHEHCBFB_00408	1121115.AXVN01000008_gene2673	0.0	1007.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3XZGV@572511|Blautia	186801|Clostridia	E	Psort location Cellwall, score	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NHEHCBFB_00409	457412.RSAG_02546	3.96e-194	540.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WIY9@541000|Ruminococcaceae	186801|Clostridia	P	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
NHEHCBFB_00410	1121115.AXVN01000008_gene2675	9.37e-206	571.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XZG8@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NHEHCBFB_00411	1121115.AXVN01000008_gene2676	2.91e-215	595.0	COG0583@1|root,COG0583@2|Bacteria,1V5MW@1239|Firmicutes,24J0X@186801|Clostridia,3Y0IH@572511|Blautia	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1
NHEHCBFB_00412	1121115.AXVN01000008_gene2678	9.03e-298	816.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,3XZ1B@572511|Blautia	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
NHEHCBFB_00413	1121115.AXVN01000008_gene2679	5.47e-159	445.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia,3XZ6R@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
NHEHCBFB_00414	1121115.AXVN01000008_gene2680	8.06e-199	551.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia,3XYU6@572511|Blautia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
NHEHCBFB_00415	457412.RSAG_02553	2.61e-147	415.0	COG2364@1|root,COG2364@2|Bacteria,1V1ZQ@1239|Firmicutes,24GEW@186801|Clostridia,3WRWZ@541000|Ruminococcaceae	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
NHEHCBFB_00416	1121115.AXVN01000008_gene2682	3.52e-253	695.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,3XZ5V@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
NHEHCBFB_00417	1121115.AXVN01000008_gene2683	2.5e-153	431.0	COG3341@1|root,COG3341@2|Bacteria,1UIS0@1239|Firmicutes,25EQZ@186801|Clostridia	186801|Clostridia	L	Caulimovirus viroplasmin	rnhA	-	-	ko:K06993	-	-	-	-	ko00000	-	-	-	Cauli_VI,RNase_H
NHEHCBFB_00418	1121115.AXVN01000008_gene2684	7.37e-273	748.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3Y04D@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R04880,R05233,R05234,R06917,R06927	RC00050,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NHEHCBFB_00419	457412.RSAG_02563	0.0	982.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia,3WHIY@541000|Ruminococcaceae	186801|Clostridia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
NHEHCBFB_00420	457412.RSAG_02564	3.86e-142	401.0	COG1102@1|root,COG1102@2|Bacteria,1V74C@1239|Firmicutes,24EKT@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NHEHCBFB_00421	457412.RSAG_02565	7.77e-301	819.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3WGQA@541000|Ruminococcaceae	186801|Clostridia	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NHEHCBFB_00422	457412.RSAG_02566	3.39e-132	374.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V5G6@1239|Firmicutes,24928@186801|Clostridia,3WKCT@541000|Ruminococcaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
NHEHCBFB_00423	1121115.AXVN01000008_gene2688	0.0	1125.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3XZCN@572511|Blautia	186801|Clostridia	H	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NHEHCBFB_00424	457412.RSAG_02568	9.88e-111	319.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia,3WJE7@541000|Ruminococcaceae	186801|Clostridia	E	Small subunit of acetolactate synthase	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
NHEHCBFB_00425	457412.RSAG_02569	1.58e-302	825.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3WGV5@541000|Ruminococcaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
NHEHCBFB_00426	457412.RSAG_02570	9.05e-170	474.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,3WIW2@541000|Ruminococcaceae	186801|Clostridia	E	PHP domain protein	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
NHEHCBFB_00427	1121115.AXVN01000008_gene2689	5.72e-74	224.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia,3XZ1J@572511|Blautia	186801|Clostridia	E	COG COG0440 Acetolactate synthase, small (regulatory) subunit	ilvH_1	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
NHEHCBFB_00428	1121115.AXVN01000008_gene2712	8.49e-128	365.0	COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,249YQ@186801|Clostridia,3XZCZ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
NHEHCBFB_00429	1121115.AXVN01000008_gene2713	5.83e-224	618.0	COG3191@1|root,COG3191@2|Bacteria,1TP60@1239|Firmicutes,24AVR@186801|Clostridia,3XZ5P@572511|Blautia	186801|Clostridia	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
NHEHCBFB_00430	1121115.AXVN01000008_gene2715	6.33e-66	212.0	COG0738@1|root,COG0738@2|Bacteria,1TQPE@1239|Firmicutes,24AF8@186801|Clostridia,3XYNH@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NHEHCBFB_00431	457412.RSAG_02578	4.82e-178	496.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,3WG8S@541000|Ruminococcaceae	186801|Clostridia	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
NHEHCBFB_00432	1121115.AXVN01000008_gene2717	3.7e-16	72.0	2FAZC@1|root,34364@2|Bacteria,1VXA9@1239|Firmicutes,252GU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00433	1121115.AXVN01000008_gene2719	0.0	922.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3XZ4X@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
NHEHCBFB_00434	457412.RSAG_02582	1.45e-129	367.0	28PZ1@1|root,2ZCII@2|Bacteria,1V2GX@1239|Firmicutes,24IE1@186801|Clostridia,3WK3Z@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3877
NHEHCBFB_00435	457412.RSAG_02584	0.0	1073.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3WGN6@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
NHEHCBFB_00436	457412.RSAG_02585	0.0	1659.0	COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,24B8I@186801|Clostridia,3WI73@541000|Ruminococcaceae	186801|Clostridia	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
NHEHCBFB_00437	457412.RSAG_02586	3.61e-212	586.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3WI8A@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_00438	1121115.AXVN01000157_gene539	0.0	1169.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3XZ6T@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
NHEHCBFB_00439	180332.JTGN01000006_gene3325	2.92e-43	162.0	COG2710@1|root,COG2710@2|Bacteria,1TRSJ@1239|Firmicutes,24AEW@186801|Clostridia	186801|Clostridia	C	Nitrogenase molybdenum-iron protein, alpha and beta chains	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_nitro
NHEHCBFB_00440	180332.JTGN01000006_gene3326	3.29e-92	281.0	COG1348@1|root,COG1348@2|Bacteria,1TPXR@1239|Firmicutes,247KJ@186801|Clostridia	186801|Clostridia	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	-	-	1.18.6.1,1.3.7.7	ko:K02588,ko:K04037	ko00625,ko00860,ko00910,ko01100,ko01110,ko01120,map00625,map00860,map00910,map01100,map01110,map01120	M00175	R05185,R05496,R06282	RC00002,RC01008,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
NHEHCBFB_00441	180332.JTGN01000006_gene3327	4.04e-109	323.0	COG1120@1|root,COG1120@2|Bacteria,1UYT8@1239|Firmicutes,24CJY@186801|Clostridia	186801|Clostridia	HP	Abc transporter	-	-	3.6.3.34	ko:K02013,ko:K09820	ko02010,map02010	M00240,M00243	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14,3.A.1.15	-	-	ABC_tran
NHEHCBFB_00442	180332.JTGN01000006_gene3328	1.88e-140	408.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NHEHCBFB_00443	903814.ELI_1719	9.23e-82	260.0	COG0614@1|root,COG0614@2|Bacteria,1TQ11@1239|Firmicutes,2482R@186801|Clostridia,25X5J@186806|Eubacteriaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
NHEHCBFB_00444	180332.JTGN01000006_gene3330	1.2e-151	435.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_00445	33035.JPJF01000009_gene1487	1.71e-290	806.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NHEHCBFB_00446	457412.RSAG_02597	0.0	1211.0	COG0426@1|root,COG1773@1|root,COG1853@1|root,COG0426@2|Bacteria,COG1773@2|Bacteria,COG1853@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_5,Lactamase_B
NHEHCBFB_00447	457412.RSAG_02598	4.17e-281	768.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,3WIXP@541000|Ruminococcaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NHEHCBFB_00448	457412.RSAG_02599	0.0	1246.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,3WHAU@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
NHEHCBFB_00449	1121115.AXVN01000089_gene2818	1.86e-206	572.0	COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia,3Y072@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NHEHCBFB_00450	1121115.AXVN01000089_gene2817	0.0	1859.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3Y1DS@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
NHEHCBFB_00451	1121115.AXVN01000089_gene2816	0.0	1198.0	COG0737@1|root,COG1653@1|root,COG0737@2|Bacteria,COG1653@2|Bacteria,1U6YH@1239|Firmicutes,24ENB@186801|Clostridia,3Y15J@572511|Blautia	186801|Clostridia	FG	ABC transporter substrate-binding protein	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_00452	1121115.AXVN01000089_gene2815	0.0	1290.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3Y1FS@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
NHEHCBFB_00453	1121115.AXVN01000089_gene2814	1.69e-191	531.0	COG0834@1|root,COG0834@2|Bacteria,1UYKY@1239|Firmicutes,24C0B@186801|Clostridia,3Y14K@572511|Blautia	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NHEHCBFB_00454	1121115.AXVN01000148_gene3602	0.0	1561.0	COG4403@1|root,COG4403@2|Bacteria,1TS6F@1239|Firmicutes,247JU@186801|Clostridia,3XZVN@572511|Blautia	186801|Clostridia	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
NHEHCBFB_00455	1121115.AXVN01000148_gene3603	5.68e-117	335.0	2EGBC@1|root,33A36@2|Bacteria,1UKIB@1239|Firmicutes,24VNX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00456	1121115.AXVN01000148_gene3604	1.06e-19	82.0	2E98V@1|root,333H5@2|Bacteria,1VI8K@1239|Firmicutes,24RMD@186801|Clostridia	186801|Clostridia	S	BhlA holin family	-	-	-	-	-	-	-	-	-	-	-	-	Holin_BhlA
NHEHCBFB_00458	457412.RSAG_02818	0.0	1375.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Polysacc_lyase,SLH
NHEHCBFB_00459	457412.RSAG_02452	2.63e-19	87.0	2DUPK@1|root,33RK6@2|Bacteria,1VRQV@1239|Firmicutes,24YX7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00460	457412.RSAG_02820	1.49e-164	461.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3WG98@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_00461	1121115.AXVN01000057_gene2517	0.0	1598.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,3XYHV@572511|Blautia	186801|Clostridia	V	COG COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NHEHCBFB_00462	556261.HMPREF0240_04213	5.23e-135	389.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,24931@186801|Clostridia,36E2H@31979|Clostridiaceae	186801|Clostridia	K	transcriptional antiterminator	licT	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
NHEHCBFB_00463	658655.HMPREF0988_00931	1.07e-72	222.0	COG2190@1|root,COG2190@2|Bacteria,1W092@1239|Firmicutes,25EGH@186801|Clostridia,27UE8@186928|unclassified Lachnospiraceae	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1	ptbA	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1
NHEHCBFB_00464	658655.HMPREF0988_00930	3.49e-298	820.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,27JKG@186928|unclassified Lachnospiraceae	186801|Clostridia	G	phosphotransferase system, EIIB	nagE	-	2.7.1.193	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIB,PTS_EIIC
NHEHCBFB_00465	397288.C806_01835	3.15e-06	52.4	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,1VR4E@1239|Firmicutes,24ZX9@186801|Clostridia,27R20@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
NHEHCBFB_00466	1304866.K413DRAFT_2113	7.77e-53	177.0	COG1802@1|root,COG1802@2|Bacteria,1UX0V@1239|Firmicutes,25MUT@186801|Clostridia,36TTV@31979|Clostridiaceae	186801|Clostridia	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NHEHCBFB_00467	742735.HMPREF9467_05084	1.16e-150	435.0	COG0399@1|root,COG0399@2|Bacteria,1V9T5@1239|Firmicutes,24F34@186801|Clostridia,21ZPY@1506553|Lachnoclostridium	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00468	411902.CLOBOL_01070	3.91e-187	524.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,21XHD@1506553|Lachnoclostridium	186801|Clostridia	P	COG COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NHEHCBFB_00469	742735.HMPREF9467_05082	1e-147	423.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,21YVI@1506553|Lachnoclostridium	186801|Clostridia	P	N-terminal TM domain of oligopeptide transport permease C	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
NHEHCBFB_00470	411902.CLOBOL_01072	6.12e-161	459.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,21XI0@1506553|Lachnoclostridium	186801|Clostridia	P	COG COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
NHEHCBFB_00471	411902.CLOBOL_01073	3.82e-185	520.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,21YV5@1506553|Lachnoclostridium	186801|Clostridia	P	COG COG4608 ABC-type oligopeptide transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
NHEHCBFB_00472	742735.HMPREF9467_05079	5.1e-262	732.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,21ZXU@1506553|Lachnoclostridium	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
NHEHCBFB_00473	1304866.K413DRAFT_2120	4.22e-147	418.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24B66@186801|Clostridia,36W4B@31979|Clostridiaceae	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
NHEHCBFB_00474	1304866.K413DRAFT_2121	3.71e-195	548.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia,36F05@31979|Clostridiaceae	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
NHEHCBFB_00475	1121115.AXVN01000057_gene2519	0.0	1808.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3XYWB@572511|Blautia	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
NHEHCBFB_00476	457412.RSAG_02825	0.0	1349.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia,3WSDQ@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
NHEHCBFB_00477	457412.RSAG_02826	8.66e-316	859.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3WGW8@541000|Ruminococcaceae	186801|Clostridia	H	Mur ligase middle domain	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
NHEHCBFB_00478	1121115.AXVN01000057_gene2522	3.2e-27	99.0	2EGDA@1|root,33A54@2|Bacteria,1VKC8@1239|Firmicutes,258G8@186801|Clostridia,3Y0SU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00479	457412.RSAG_02828	7.37e-269	742.0	COG0457@1|root,COG0457@2|Bacteria,1UI34@1239|Firmicutes,25F0K@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
NHEHCBFB_00480	1121115.AXVN01000057_gene2524	2.76e-70	211.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,3Y0KP@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
NHEHCBFB_00481	1121115.AXVN01000057_gene2525	3.68e-97	282.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,3Y0A1@572511|Blautia	186801|Clostridia	H	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
NHEHCBFB_00482	1121115.AXVN01000057_gene2526	4.08e-157	442.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia,3XZEX@572511|Blautia	186801|Clostridia	K	COG COG1191 DNA-directed RNA polymerase specialized sigma subunit	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
NHEHCBFB_00484	457412.RSAG_02832	1.72e-109	315.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,3WKVC@541000|Ruminococcaceae	186801|Clostridia	S	QueT transporter	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
NHEHCBFB_00485	1121115.AXVN01000057_gene2528	2.08e-145	409.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,24DN2@186801|Clostridia,3XZTN@572511|Blautia	186801|Clostridia	S	Psort location	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
NHEHCBFB_00486	457412.RSAG_02834	2.69e-79	235.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,3WK2T@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
NHEHCBFB_00487	457412.RSAG_02835	6.75e-270	737.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,25EAS@186801|Clostridia,3WGIZ@541000|Ruminococcaceae	186801|Clostridia	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
NHEHCBFB_00488	1121115.AXVN01000057_gene2531	4.87e-106	306.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,3Y02E@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
NHEHCBFB_00489	1121115.AXVN01000057_gene2532	8.08e-100	289.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,24RBI@186801|Clostridia,3Y0C4@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
NHEHCBFB_00490	457412.RSAG_02838	3.2e-212	587.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3WGX6@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
NHEHCBFB_00491	457412.RSAG_02839	9.96e-212	585.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,3WGDD@541000|Ruminococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
NHEHCBFB_00492	1121115.AXVN01000046_gene2988	3.83e-232	640.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,3XYJH@572511|Blautia	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
NHEHCBFB_00493	1121115.AXVN01000046_gene2987	1.27e-50	160.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,3Y2CC@572511|Blautia	186801|Clostridia	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NHEHCBFB_00494	1121115.AXVN01000046_gene2986	6.71e-235	650.0	COG0681@1|root,COG0681@2|Bacteria,1VGJ6@1239|Firmicutes,24SUY@186801|Clostridia,3Y28M@572511|Blautia	186801|Clostridia	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00495	1121115.AXVN01000046_gene2985	3.91e-66	201.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,3XZZ4@572511|Blautia	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
NHEHCBFB_00496	1121115.AXVN01000046_gene2984	1.77e-149	420.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3XZ95@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
NHEHCBFB_00497	1121115.AXVN01000046_gene2983	4.85e-136	386.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
NHEHCBFB_00498	1121115.AXVN01000046_gene2982	7.84e-61	187.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,3Y06M@572511|Blautia	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
NHEHCBFB_00499	457412.RSAG_02847	3.72e-200	554.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WGQK@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
NHEHCBFB_00500	1121115.AXVN01000046_gene2980	1.77e-61	188.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3Y09D@572511|Blautia	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
NHEHCBFB_00501	1121115.AXVN01000046_gene2979	5.64e-84	248.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3XZZ2@572511|Blautia	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
NHEHCBFB_00502	1121115.AXVN01000046_gene2978	3.41e-151	425.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3XZ7Y@572511|Blautia	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
NHEHCBFB_00503	1121115.AXVN01000046_gene2977	1.88e-101	293.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3XYIJ@572511|Blautia	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
NHEHCBFB_00504	457412.RSAG_02852	1.39e-36	124.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WKVV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
NHEHCBFB_00505	457412.RSAG_02853	4.6e-53	166.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,3WJV0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
NHEHCBFB_00506	1121115.AXVN01000046_gene2974	1.8e-79	236.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,3XZZG@572511|Blautia	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
NHEHCBFB_00507	1121115.AXVN01000046_gene2973	2.29e-64	196.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3Y0BX@572511|Blautia	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
NHEHCBFB_00508	457412.RSAG_02856	9.39e-123	350.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,3WGYQ@541000|Ruminococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
NHEHCBFB_00509	1121115.AXVN01000046_gene2971	4.1e-39	129.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,3Y0DU@572511|Blautia	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
NHEHCBFB_00510	1121115.AXVN01000046_gene2970	8.56e-90	263.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,3Y02G@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
NHEHCBFB_00511	1121115.AXVN01000046_gene2969	1.21e-109	317.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,3XYVK@572511|Blautia	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
NHEHCBFB_00512	1121115.AXVN01000046_gene2968	1.22e-77	231.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3XZZX@572511|Blautia	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
NHEHCBFB_00513	1121115.AXVN01000046_gene2967	1.46e-112	323.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
NHEHCBFB_00514	1121115.AXVN01000046_gene2966	1.2e-33	115.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,3Y0NM@572511|Blautia	186801|Clostridia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
NHEHCBFB_00515	1121115.AXVN01000046_gene2965	2.1e-94	276.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3XZUB@572511|Blautia	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
NHEHCBFB_00516	457412.RSAG_02864	1.31e-302	827.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,3WG8Z@541000|Ruminococcaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
NHEHCBFB_00517	1121115.AXVN01000046_gene2963	4.7e-156	437.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3XZAB@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
NHEHCBFB_00518	1121115.AXVN01000046_gene2962	3.05e-184	511.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3XZ5M@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
NHEHCBFB_00519	1121115.AXVN01000046_gene2961	4.86e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,3Y0HJ@572511|Blautia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
NHEHCBFB_00520	1121115.AXVN01000046_gene2959	2.1e-78	233.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3Y043@572511|Blautia	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
NHEHCBFB_00521	1121115.AXVN01000046_gene2958	2.78e-85	251.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3XZVK@572511|Blautia	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
NHEHCBFB_00522	457412.RSAG_02872	5.13e-138	390.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
NHEHCBFB_00523	457412.RSAG_02873	5.58e-221	610.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WGUM@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
NHEHCBFB_00524	1121115.AXVN01000046_gene2955	1.28e-115	332.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,3XZ2H@572511|Blautia	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
NHEHCBFB_00525	457412.RSAG_02876	4.59e-217	598.0	COG0584@1|root,COG0584@2|Bacteria,1TUUB@1239|Firmicutes,259V0@186801|Clostridia,3WQRJ@541000|Ruminococcaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00526	457412.RSAG_02877	0.0	895.0	COG0769@1|root,COG0769@2|Bacteria,1UHY9@1239|Firmicutes,25E6X@186801|Clostridia,3WHF5@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
NHEHCBFB_00527	457412.RSAG_02878	9.84e-180	499.0	COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,24A80@186801|Clostridia,3WHHU@541000|Ruminococcaceae	186801|Clostridia	S	glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
NHEHCBFB_00528	1121115.AXVN01000046_gene2951	6.36e-134	380.0	COG2378@1|root,COG2378@2|Bacteria,1UH6Q@1239|Firmicutes,2504G@186801|Clostridia,3Y0EB@572511|Blautia	186801|Clostridia	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00529	457412.RSAG_02881	3.01e-314	862.0	COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,3WHCQ@541000|Ruminococcaceae	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10546	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	Peripla_BP_4
NHEHCBFB_00530	1121115.AXVN01000046_gene2949	4.41e-131	372.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia,3XZCM@572511|Blautia	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
NHEHCBFB_00531	1121115.AXVN01000046_gene2948	7.08e-49	155.0	2ES6S@1|root,33JRI@2|Bacteria,1VQGH@1239|Firmicutes,24WUX@186801|Clostridia,3Y0HU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00532	1121115.AXVN01000046_gene2947	3.88e-73	219.0	COG1937@1|root,COG1937@2|Bacteria,1VA7S@1239|Firmicutes,24NNH@186801|Clostridia,3Y061@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NHEHCBFB_00533	1121115.AXVN01000084_gene1836	4.88e-198	548.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,3XYU0@572511|Blautia	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
NHEHCBFB_00534	1121115.AXVN01000084_gene1835	2.49e-205	568.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3XZ9N@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_00535	1121115.AXVN01000084_gene1834	0.0	2496.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,3XYY2@572511|Blautia	186801|Clostridia	F	bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain glutamine amidotransferase domain)	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
NHEHCBFB_00537	1123075.AUDP01000020_gene1533	1.25e-101	324.0	COG3942@1|root,COG3942@2|Bacteria	2|Bacteria	S	pathogenesis	usp	-	3.5.1.28	ko:K21471,ko:K22409	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	CHAP,LysM
NHEHCBFB_00538	457412.RSAG_00449	4.71e-261	736.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,3WGJR@541000|Ruminococcaceae	186801|Clostridia	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
NHEHCBFB_00540	1121115.AXVN01000084_gene1833	1.23e-166	466.0	2EXDX@1|root,33QQG@2|Bacteria,1VTSR@1239|Firmicutes,24YUS@186801|Clostridia,3Y1G7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00541	1347392.CCEZ01000014_gene2764	1.78e-26	117.0	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,1TT2K@1239|Firmicutes,24965@186801|Clostridia	186801|Clostridia	M	Peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,BsuPI,LysM,PG_binding_1
NHEHCBFB_00542	679200.HMPREF9333_01225	1.45e-15	78.2	COG1690@1|root,COG1690@2|Bacteria,1TPJ2@1239|Firmicutes,2481V@186801|Clostridia	186801|Clostridia	S	Belongs to the RtcB family	-	-	-	-	-	-	-	-	-	-	-	-	RtcB
NHEHCBFB_00543	1121115.AXVN01000084_gene1830	1.52e-241	665.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,3XZSW@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
NHEHCBFB_00544	1121115.AXVN01000084_gene1829	2.63e-135	385.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia,3XYKJ@572511|Blautia	186801|Clostridia	P	COG COG2011 ABC-type metal ion transport system, permease component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
NHEHCBFB_00545	457412.RSAG_02896	4.35e-191	534.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,3WH0R@541000|Ruminococcaceae	186801|Clostridia	P	nlpA lipoprotein	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
NHEHCBFB_00546	457412.RSAG_02899	3.75e-53	184.0	COG3210@1|root,COG4886@1|root,COG3210@2|Bacteria,COG4886@2|Bacteria,1V6R1@1239|Firmicutes,24K56@186801|Clostridia	186801|Clostridia	U	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
NHEHCBFB_00548	1280698.AUJS01000008_gene873	6.29e-52	164.0	COG3070@1|root,COG3070@2|Bacteria,1V42M@1239|Firmicutes,24JNV@186801|Clostridia,27WUX@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
NHEHCBFB_00549	411459.RUMOBE_03329	0.0	1229.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3Y1GK@572511|Blautia	186801|Clostridia	L	COG COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,SpoVT_C,Zn_ribbon_recom
NHEHCBFB_00550	457412.RSAG_02096	2.03e-120	350.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia,3WHSG@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
NHEHCBFB_00551	1121115.AXVN01000063_gene713	7.85e-265	725.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XYK4@572511|Blautia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	ugpC_1	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
NHEHCBFB_00552	1121115.AXVN01000063_gene712	1.76e-257	706.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,25N06@186801|Clostridia,3XYXQ@572511|Blautia	186801|Clostridia	KT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NHEHCBFB_00553	457412.RSAG_04588	1.07e-262	718.0	COG3842@1|root,COG3842@2|Bacteria,1TQ18@1239|Firmicutes,24AEK@186801|Clostridia,3WGIR@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
NHEHCBFB_00554	1121115.AXVN01000063_gene710	2.03e-154	434.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,3XZF3@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
NHEHCBFB_00555	1121115.AXVN01000063_gene709	4.67e-184	515.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,3Y07V@572511|Blautia	186801|Clostridia	P	COG COG0725 ABC-type molybdate transport system, periplasmic component	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
NHEHCBFB_00556	1121115.AXVN01000063_gene708	2.67e-39	130.0	COG3585@1|root,COG3585@2|Bacteria,1VEPR@1239|Firmicutes,24QTI@186801|Clostridia	186801|Clostridia	H	pfam tobe	mopI	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	TOBE
NHEHCBFB_00557	457412.RSAG_02102	1.65e-214	593.0	COG1910@1|root,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,3WHAS@541000|Ruminococcaceae	186801|Clostridia	P	TIGRFAM DNA binding domain	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_17,PBP_like
NHEHCBFB_00558	457412.RSAG_02103	2.71e-237	653.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WGRJ@541000|Ruminococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
NHEHCBFB_00559	1121115.AXVN01000063_gene705	0.0	2088.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,3XYH9@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
NHEHCBFB_00560	1121115.AXVN01000063_gene704	7.86e-268	732.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,3XYS9@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
NHEHCBFB_00562	457412.RSAG_02106	7.3e-268	733.0	COG4733@1|root,COG4733@2|Bacteria,1VDWT@1239|Firmicutes,24ZKB@186801|Clostridia,3WMCI@541000|Ruminococcaceae	186801|Clostridia	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
NHEHCBFB_00563	1121115.AXVN01000063_gene702	9.72e-314	860.0	COG4886@1|root,COG5492@1|root,COG4886@2|Bacteria,COG5492@2|Bacteria,1VRK1@1239|Firmicutes,25KN7@186801|Clostridia,3Y1XU@572511|Blautia	186801|Clostridia	N	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00564	1121115.AXVN01000063_gene701	1.37e-100	295.0	2DR5I@1|root,33A9E@2|Bacteria,1VM5P@1239|Firmicutes,24JQJ@186801|Clostridia,3Y0KF@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
NHEHCBFB_00565	1121115.AXVN01000063_gene700	0.0	907.0	COG1219@1|root,COG1219@2|Bacteria,1TPDI@1239|Firmicutes,24AEG@186801|Clostridia,3XYQ7@572511|Blautia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX_1	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
NHEHCBFB_00566	1121115.AXVN01000072_gene3906	0.0	878.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3XZRU@572511|Blautia	186801|Clostridia	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
NHEHCBFB_00567	1121115.AXVN01000072_gene3907	6.16e-236	647.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia,3XZN2@572511|Blautia	186801|Clostridia	S	LPS side chain defect rhamnosyl transferase	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
NHEHCBFB_00568	1121115.AXVN01000072_gene3908	4.75e-275	760.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,3XYM4@572511|Blautia	186801|Clostridia	K	COG COG1316 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
NHEHCBFB_00569	457412.RSAG_02113	0.0	910.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,3WRHZ@541000|Ruminococcaceae	186801|Clostridia	M	CoA-binding domain	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
NHEHCBFB_00570	1121115.AXVN01000072_gene3910	1.07e-238	655.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,249WH@186801|Clostridia,3XYQG@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
NHEHCBFB_00571	1121115.AXVN01000072_gene3911	0.0	1298.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3XYRF@572511|Blautia	186801|Clostridia	M	Glycosyltransferase like family	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
NHEHCBFB_00572	1121115.AXVN01000072_gene3912	1.18e-292	800.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3XZGM@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NHEHCBFB_00573	457412.RSAG_02117	0.0	989.0	COG1807@1|root,COG1807@2|Bacteria,1V22V@1239|Firmicutes,24GKH@186801|Clostridia,3WK06@541000|Ruminococcaceae	186801|Clostridia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT,PMT_2
NHEHCBFB_00574	457412.RSAG_02118	0.0	1641.0	COG1216@1|root,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
NHEHCBFB_00575	457412.RSAG_02119	0.0	1654.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Methyltransf_23
NHEHCBFB_00576	457412.RSAG_02120	0.0	1455.0	COG2242@1|root,COG2242@2|Bacteria,1TPEE@1239|Firmicutes,24D9B@186801|Clostridia,3WN5Y@541000|Ruminococcaceae	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
NHEHCBFB_00577	1121115.AXVN01000072_gene3917	3.01e-311	847.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3XYUG@572511|Blautia	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score 9.49	-	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
NHEHCBFB_00578	457412.RSAG_02122	7.18e-193	535.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,248R0@186801|Clostridia,3WKBW@541000|Ruminococcaceae	186801|Clostridia	GM	ABC-2 type transporter	-	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
NHEHCBFB_00579	1121115.AXVN01000022_gene1724	1.89e-138	390.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,3XYH7@572511|Blautia	186801|Clostridia	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
NHEHCBFB_00580	457412.RSAG_02124	2.27e-289	793.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WJ4Y@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NHEHCBFB_00581	457412.RSAG_02125	3.85e-284	775.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,3WI1W@541000|Ruminococcaceae	186801|Clostridia	E	DegT/DnrJ/EryC1/StrS aminotransferase family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
NHEHCBFB_00582	1121115.AXVN01000022_gene1727	0.0	864.0	COG0027@1|root,COG0027@2|Bacteria,1VR1C@1239|Firmicutes,25M0G@186801|Clostridia,3XZT7@572511|Blautia	186801|Clostridia	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
NHEHCBFB_00583	1121115.AXVN01000022_gene1728	4.88e-236	648.0	COG0399@1|root,COG0399@2|Bacteria,1TZB6@1239|Firmicutes,249QE@186801|Clostridia,3Y0S8@572511|Blautia	186801|Clostridia	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00584	1121115.AXVN01000022_gene1729	3.35e-218	602.0	COG0463@1|root,COG0463@2|Bacteria,1TRFA@1239|Firmicutes,249CR@186801|Clostridia,3XZM2@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
NHEHCBFB_00585	1121115.AXVN01000022_gene1730	1.84e-76	228.0	COG0697@1|root,COG0697@2|Bacteria,1UHS0@1239|Firmicutes,25FFB@186801|Clostridia,3Y0C7@572511|Blautia	186801|Clostridia	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NHEHCBFB_00586	457412.RSAG_02130	4.97e-70	211.0	COG2076@1|root,COG2076@2|Bacteria,1VFDI@1239|Firmicutes,24S4I@186801|Clostridia,3WKQ8@541000|Ruminococcaceae	186801|Clostridia	P	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NHEHCBFB_00587	1121115.AXVN01000022_gene1732	0.0	976.0	COG3757@1|root,COG5263@1|root,COG3757@2|Bacteria,COG5263@2|Bacteria,1TPVT@1239|Firmicutes,24DEH@186801|Clostridia,3Y010@572511|Blautia	186801|Clostridia	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Glyco_hydro_25
NHEHCBFB_00588	457412.RSAG_02132	0.0	1609.0	COG1376@1|root,COG5263@1|root,COG1376@2|Bacteria,COG5263@2|Bacteria,1V0DN@1239|Firmicutes,24BCJ@186801|Clostridia,3WGYS@541000|Ruminococcaceae	186801|Clostridia	D	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,YkuD
NHEHCBFB_00589	457412.RSAG_02133	3.05e-57	177.0	COG1925@1|root,COG1925@2|Bacteria,1VA23@1239|Firmicutes,24N32@186801|Clostridia,3WM6W@541000|Ruminococcaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NHEHCBFB_00590	1121115.AXVN01000022_gene1735	1.03e-300	822.0	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,24IXJ@186801|Clostridia,3Y2B7@572511|Blautia	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
NHEHCBFB_00591	457412.RSAG_02135	5.63e-198	550.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,3WGY9@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
NHEHCBFB_00592	457412.RSAG_02137	7.29e-247	679.0	28K89@1|root,2Z9W3@2|Bacteria,1V1PZ@1239|Firmicutes,24D2W@186801|Clostridia,3WIZQ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00593	1121115.AXVN01000022_gene1738	7.07e-92	269.0	2DIZ6@1|root,32UC0@2|Bacteria,1VGDB@1239|Firmicutes,24SFK@186801|Clostridia,3Y0CW@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00594	457412.RSAG_02139	1.34e-174	486.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,3WKFF@541000|Ruminococcaceae	186801|Clostridia	S	Phosphoribosyl transferase domain	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
NHEHCBFB_00595	1121115.AXVN01000022_gene1740	0.0	1460.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,3XYVD@572511|Blautia	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
NHEHCBFB_00596	1121115.AXVN01000022_gene1741	1.13e-225	623.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,3XZC7@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
NHEHCBFB_00597	1121115.AXVN01000022_gene1742	0.0	1869.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3XYNU@572511|Blautia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
NHEHCBFB_00598	457412.RSAG_02145	8.39e-281	766.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,3WGN4@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
NHEHCBFB_00599	1121115.AXVN01000022_gene1744	2.17e-46	152.0	2CAIE@1|root,33XMU@2|Bacteria,1VVJ5@1239|Firmicutes,2511G@186801|Clostridia,3Y25M@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00600	1121115.AXVN01000022_gene1745	0.0	1182.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3XYYN@572511|Blautia	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
NHEHCBFB_00601	457412.RSAG_02148	4.34e-283	777.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,3WGV1@541000|Ruminococcaceae	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
NHEHCBFB_00602	1121115.AXVN01000022_gene1747	3.32e-210	582.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,3XYQQ@572511|Blautia	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
NHEHCBFB_00603	457412.RSAG_02150	2.61e-17	76.6	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3WKKU@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
NHEHCBFB_00604	457412.RSAG_02151	3.98e-230	634.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,3WH6N@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
NHEHCBFB_00605	457412.RSAG_02152	5.61e-223	614.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WGEP@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
NHEHCBFB_00606	457412.RSAG_02153	5.84e-123	351.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia,3WJC2@541000|Ruminococcaceae	186801|Clostridia	S	3H domain	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
NHEHCBFB_00607	1121115.AXVN01000022_gene1752	3.14e-193	537.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,3XZ2V@572511|Blautia	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
NHEHCBFB_00608	1121115.AXVN01000022_gene1753	6.78e-316	859.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,3XZEH@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 9.36	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
NHEHCBFB_00609	457412.RSAG_02156	0.0	1492.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WH2S@541000|Ruminococcaceae	186801|Clostridia	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
NHEHCBFB_00610	457412.RSAG_02157	1.25e-214	593.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia,3WJJR@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
NHEHCBFB_00611	1121115.AXVN01000022_gene1756	0.0	945.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XYXC@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
NHEHCBFB_00612	457412.RSAG_02159	5.44e-181	503.0	COG5632@1|root,COG5632@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PG_binding_1,SPOR
NHEHCBFB_00613	457412.RSAG_02160	2.89e-100	290.0	COG4824@1|root,COG4824@2|Bacteria,1V934@1239|Firmicutes,24MXR@186801|Clostridia,3WRW2@541000|Ruminococcaceae	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
NHEHCBFB_00614	457412.RSAG_00904	0.0	893.0	COG5279@1|root,COG5279@2|Bacteria,1V2RG@1239|Firmicutes,24GD8@186801|Clostridia	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NHEHCBFB_00617	457412.RSAG_00907	1.28e-205	570.0	COG0679@1|root,COG0679@2|Bacteria,1TRAI@1239|Firmicutes,24HU9@186801|Clostridia,3WPNA@541000|Ruminococcaceae	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NHEHCBFB_00618	457412.RSAG_00908	4.19e-212	587.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,3WI1Q@541000|Ruminococcaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NHEHCBFB_00619	457412.RSAG_00909	1.24e-137	391.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_00620	457412.RSAG_00910	0.0	882.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_00621	742765.HMPREF9457_01244	5.59e-184	513.0	COG4336@1|root,COG4336@2|Bacteria,1TRY8@1239|Firmicutes,248UQ@186801|Clostridia	186801|Clostridia	S	Belongs to the D-glutamate cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1445
NHEHCBFB_00622	1121115.AXVN01000061_gene498	3.12e-238	660.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,3XYMM@572511|Blautia	186801|Clostridia	S	N-methylation of lysine residues in flagellin	fliU	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
NHEHCBFB_00623	1410626.JHXB01000024_gene404	7.9e-26	106.0	2CHC9@1|root,346TJ@2|Bacteria,1VYZJ@1239|Firmicutes,253CK@186801|Clostridia,27QIU@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00624	457412.RSAG_00912	9.31e-17	74.7	COG4422@1|root,COG4422@2|Bacteria,1TPP1@1239|Firmicutes,248RZ@186801|Clostridia,3WHGZ@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4186,DUF5131
NHEHCBFB_00625	457412.RSAG_00913	1.12e-134	381.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,24GD7@186801|Clostridia,3WK2W@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
NHEHCBFB_00626	457412.RSAG_04704	4.61e-96	283.0	2CET8@1|root,2Z7N2@2|Bacteria,1TT9T@1239|Firmicutes,24AN8@186801|Clostridia,3WIG0@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00627	457412.RSAG_00916	2.65e-212	585.0	COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia,3WSCK@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
NHEHCBFB_00628	457412.RSAG_00917	1.43e-221	610.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3WHZJ@541000|Ruminococcaceae	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
NHEHCBFB_00630	457412.RSAG_00919	4.68e-99	288.0	2DHAX@1|root,32U8Z@2|Bacteria,1VV1S@1239|Firmicutes,250GD@186801|Clostridia,3WM8Y@541000|Ruminococcaceae	186801|Clostridia	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
NHEHCBFB_00631	457412.RSAG_00920	6.76e-246	674.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,24E6T@186801|Clostridia	186801|Clostridia	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
NHEHCBFB_00632	457412.RSAG_00921	0.0	1483.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WGIX@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
NHEHCBFB_00633	1121115.AXVN01000002_gene1364	8.23e-56	184.0	2DRHG@1|root,33BRY@2|Bacteria,1VKXA@1239|Firmicutes,24UU3@186801|Clostridia,3Y0P6@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00634	457412.RSAG_00923	0.0	1313.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WG7A@541000|Ruminococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
NHEHCBFB_00635	457412.RSAG_00924	0.0	1042.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,3WH9C@541000|Ruminococcaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
NHEHCBFB_00636	1121115.AXVN01000002_gene1361	2.47e-77	231.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,3Y05W@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
NHEHCBFB_00637	457412.RSAG_00926	6.24e-39	129.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
NHEHCBFB_00638	1121115.AXVN01000002_gene1360	2.15e-81	241.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia,3Y06K@572511|Blautia	186801|Clostridia	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
NHEHCBFB_00639	457412.RSAG_00929	4.29e-216	600.0	2E3Z2@1|root,32YW0@2|Bacteria,1VGF4@1239|Firmicutes,24PIY@186801|Clostridia,3WM1N@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2953)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
NHEHCBFB_00640	457412.RSAG_00930	1.18e-66	202.0	2CSSR@1|root,33IRN@2|Bacteria,1VG13@1239|Firmicutes,258FD@186801|Clostridia,3WMK4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00641	1121115.AXVN01000002_gene1357	4.04e-108	311.0	COG1051@1|root,COG1051@2|Bacteria,1V4E6@1239|Firmicutes,24HPT@186801|Clostridia,3XZUN@572511|Blautia	186801|Clostridia	F	Belongs to the Nudix hydrolase family	apfA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
NHEHCBFB_00642	1121115.AXVN01000002_gene1356	0.0	938.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,3XYMX@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
NHEHCBFB_00643	1121115.AXVN01000002_gene1355	9.73e-310	846.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,3XYN1@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
NHEHCBFB_00644	457412.RSAG_00934	0.0	1467.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,3WH8K@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
NHEHCBFB_00645	1121115.AXVN01000002_gene1353	2.16e-84	249.0	COG3027@1|root,COG3027@2|Bacteria,1V4E5@1239|Firmicutes,24HQR@186801|Clostridia,3Y0AS@572511|Blautia	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
NHEHCBFB_00646	1121115.AXVN01000002_gene1352	3.72e-238	655.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,3XZK8@572511|Blautia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
NHEHCBFB_00647	457412.RSAG_00937	7.74e-131	372.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,3WIM6@541000|Ruminococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
NHEHCBFB_00648	457412.RSAG_00938	3.86e-193	535.0	COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,3WIFS@541000|Ruminococcaceae	186801|Clostridia	C	electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
NHEHCBFB_00649	1121115.AXVN01000002_gene1349	9.51e-122	348.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,3XYQD@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
NHEHCBFB_00650	457412.RSAG_00940	7.1e-162	454.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,3WHAI@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
NHEHCBFB_00651	1121115.AXVN01000002_gene1347	2.48e-127	363.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia,3XZTQ@572511|Blautia	186801|Clostridia	P	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
NHEHCBFB_00652	457412.RSAG_00942	1.5e-228	630.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,3WGC0@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
NHEHCBFB_00653	457412.RSAG_00943	0.0	872.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB
NHEHCBFB_00654	457412.RSAG_00944	1.13e-247	679.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia,3WPXI@541000|Ruminococcaceae	186801|Clostridia	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
NHEHCBFB_00655	1121115.AXVN01000002_gene1343	4.68e-152	427.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,25D1G@186801|Clostridia	186801|Clostridia	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
NHEHCBFB_00656	1121115.AXVN01000002_gene1342	2.15e-63	194.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24T7M@186801|Clostridia,3Y25G@572511|Blautia	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
NHEHCBFB_00657	1121115.AXVN01000002_gene1341	0.0	4881.0	COG1020@1|root,COG3320@1|root,COG1020@2|Bacteria,COG3320@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,3Y1GF@572511|Blautia	186801|Clostridia	Q	AMP-binding enzyme C-terminal domain	-	-	-	ko:K04784,ko:K12240	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,NAD_binding_4,PP-binding,Thioesterase
NHEHCBFB_00658	1121115.AXVN01000002_gene1341	0.0	966.0	COG1020@1|root,COG3320@1|root,COG1020@2|Bacteria,COG3320@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,3Y1GF@572511|Blautia	186801|Clostridia	Q	AMP-binding enzyme C-terminal domain	-	-	-	ko:K04784,ko:K12240	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,NAD_binding_4,PP-binding,Thioesterase
NHEHCBFB_00659	1121115.AXVN01000002_gene1340	0.0	1102.0	COG0534@1|root,COG0534@2|Bacteria,1V10K@1239|Firmicutes,24CIC@186801|Clostridia	186801|Clostridia	TV	MatE	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MatE
NHEHCBFB_00660	457412.RSAG_00949	0.0	1217.0	COG1520@1|root,COG1520@2|Bacteria,1TQ7F@1239|Firmicutes,249BV@186801|Clostridia,3WHZZ@541000|Ruminococcaceae	186801|Clostridia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
NHEHCBFB_00661	1121115.AXVN01000002_gene1338	6.84e-90	263.0	2CJZW@1|root,30J0V@2|Bacteria,1UVFN@1239|Firmicutes,2596T@186801|Clostridia,3Y21H@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00662	457412.RSAG_00951	2.35e-206	570.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,3WGB9@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
NHEHCBFB_00664	1124982.MSI_07840	9.3e-21	86.3	2DPN2@1|root,332QJ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
NHEHCBFB_00667	97139.C824_00548	8.62e-122	367.0	COG4637@1|root,COG4637@2|Bacteria,1VE6R@1239|Firmicutes,24PN4@186801|Clostridia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
NHEHCBFB_00669	500632.CLONEX_02045	2.9e-36	135.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
NHEHCBFB_00671	748224.HMPREF9436_00577	1.41e-70	223.0	COG1961@1|root,COG1961@2|Bacteria,1V247@1239|Firmicutes,24GH4@186801|Clostridia,3WK7M@541000|Ruminococcaceae	186801|Clostridia	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00672	1449050.JNLE01000003_gene1838	6.58e-194	566.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,2492M@186801|Clostridia,36HH4@31979|Clostridiaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
NHEHCBFB_00673	1123009.AUID01000008_gene813	2.71e-102	310.0	COG3598@1|root,COG3598@2|Bacteria,1UIBK@1239|Firmicutes,24K1Q@186801|Clostridia,26A1Q@186813|unclassified Clostridiales	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Prim-Pol
NHEHCBFB_00674	428125.CLOLEP_03722	2.16e-19	82.8	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24SKI@186801|Clostridia,3WRBK@541000|Ruminococcaceae	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_00677	457412.RSAG_00985	2.59e-228	628.0	2DBA0@1|root,2Z80J@2|Bacteria,1TQY3@1239|Firmicutes,24B0S@186801|Clostridia,3WJD6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
NHEHCBFB_00678	457412.RSAG_00986	8.74e-139	393.0	COG1396@1|root,COG1396@2|Bacteria,1UZN9@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_00679	457412.RSAG_00987	1.92e-89	261.0	COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,24JFW@186801|Clostridia,3WK5Z@541000|Ruminococcaceae	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
NHEHCBFB_00681	457412.RSAG_00990	1.05e-44	144.0	COG3655@1|root,COG3655@2|Bacteria,1VH63@1239|Firmicutes	1239|Firmicutes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
NHEHCBFB_00682	457412.RSAG_00991	7.29e-61	187.0	COG1813@1|root,COG1813@2|Bacteria,1UI13@1239|Firmicutes,25FPX@186801|Clostridia,3WSNY@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_00683	457412.RSAG_00992	1.99e-314	858.0	COG0534@1|root,COG0534@2|Bacteria,1TRR0@1239|Firmicutes,249UC@186801|Clostridia,3WGYY@541000|Ruminococcaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_00684	457412.RSAG_00993	4.8e-223	615.0	COG2605@1|root,COG2605@2|Bacteria,1UY4X@1239|Firmicutes,24CIF@186801|Clostridia	186801|Clostridia	JM	L-fucokinase	-	-	2.7.1.52	ko:K05305	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R03161	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_N
NHEHCBFB_00685	457412.RSAG_04687	2.25e-121	346.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	rffH	-	2.3.1.157,2.7.7.13,2.7.7.23,2.7.7.24,5.4.2.8	ko:K00973,ko:K04042,ko:K16881	ko00051,ko00520,ko00521,ko00523,ko00525,ko01100,ko01110,ko01130,map00051,map00520,map00521,map00523,map00525,map01100,map01110,map01130	M00114,M00362,M00793	R00416,R00885,R01818,R02328,R05332	RC00002,RC00004,RC00166,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NHEHCBFB_00686	1121115.AXVN01000032_gene403	8.57e-248	681.0	COG0275@1|root,COG0275@2|Bacteria,1TP5R@1239|Firmicutes,248PH@186801|Clostridia,3XZ5Z@572511|Blautia	186801|Clostridia	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH2	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
NHEHCBFB_00687	457412.RSAG_04725	2.12e-125	357.0	COG1595@1|root,COG1595@2|Bacteria,1V8A6@1239|Firmicutes,24CUW@186801|Clostridia,3WRUA@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
NHEHCBFB_00688	1121115.AXVN01000032_gene405	5.99e-69	209.0	2EBCY@1|root,335DN@2|Bacteria,1VF9P@1239|Firmicutes,24KM6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00689	1121115.AXVN01000032_gene406	1.07e-149	421.0	2D2WM@1|root,32TDR@2|Bacteria,1VCUC@1239|Firmicutes,24GMH@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00690	457412.RSAG_04644	2.7e-138	392.0	COG2339@1|root,COG2339@2|Bacteria,1V3JI@1239|Firmicutes,24AZQ@186801|Clostridia,3WIYQ@541000|Ruminococcaceae	186801|Clostridia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
NHEHCBFB_00691	457412.RSAG_03057	5.75e-64	196.0	2E82Y@1|root,332GY@2|Bacteria,1VEU7@1239|Firmicutes,24P37@186801|Clostridia,3WQMH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00692	457412.RSAG_03051	0.0	1254.0	COG5263@1|root,COG5492@1|root,COG5263@2|Bacteria,COG5492@2|Bacteria,1VIRC@1239|Firmicutes	1239|Firmicutes	N	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00693	411461.DORFOR_02638	1.83e-260	723.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia	186801|Clostridia	E	amino acid carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ala_symp
NHEHCBFB_00694	457412.RSAG_00148	1.48e-289	791.0	COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,24B76@186801|Clostridia,3WGCD@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Dockerin_1,Serpin
NHEHCBFB_00695	1121115.AXVN01000020_gene82	0.0	1704.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3XZGZ@572511|Blautia	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
NHEHCBFB_00696	457412.RSAG_00144	0.0	1316.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,3WHC5@541000|Ruminococcaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
NHEHCBFB_00697	457412.RSAG_00143	4.61e-222	612.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3WGGD@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
NHEHCBFB_00698	1121115.AXVN01000020_gene85	2.2e-312	850.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,3XZKZ@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
NHEHCBFB_00699	457412.RSAG_00141	1.11e-284	778.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia,3WHRI@541000|Ruminococcaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
NHEHCBFB_00700	457412.RSAG_00140	0.0	1074.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,3WGFA@541000|Ruminococcaceae	186801|Clostridia	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
NHEHCBFB_00701	1121115.AXVN01000020_gene88	1.06e-169	474.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,3XZVG@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
NHEHCBFB_00702	1121115.AXVN01000020_gene89	1.2e-240	661.0	COG1077@1|root,COG1077@2|Bacteria,1TPVU@1239|Firmicutes,248CM@186801|Clostridia,3XZ2N@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
NHEHCBFB_00703	457412.RSAG_00137	5.94e-208	576.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,3WIMD@541000|Ruminococcaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
NHEHCBFB_00704	457412.RSAG_00136	8.38e-120	342.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia,3WJYV@541000|Ruminococcaceae	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
NHEHCBFB_00705	457412.RSAG_00135	0.0	1865.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,3WGCH@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
NHEHCBFB_00706	1121115.AXVN01000020_gene93	3.64e-177	494.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,3XZ45@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
NHEHCBFB_00707	457412.RSAG_00133	1.38e-59	184.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,3WJJQ@541000|Ruminococcaceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
NHEHCBFB_00708	457412.RSAG_00132	1.06e-245	678.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,3WJ15@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
NHEHCBFB_00709	1121115.AXVN01000020_gene96	9.11e-281	768.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3Y2E8@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NHEHCBFB_00710	1121115.AXVN01000020_gene97	2.8e-124	354.0	COG1896@1|root,COG1896@2|Bacteria,1V7E8@1239|Firmicutes,24DNC@186801|Clostridia,3Y0IJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06952	-	-	-	-	ko00000	-	-	-	DUF429,HD_3
NHEHCBFB_00711	1121115.AXVN01000020_gene106	1.7e-92	270.0	COG0433@1|root,COG0433@2|Bacteria,1VF8X@1239|Firmicutes,24N9T@186801|Clostridia,3Y046@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00712	1121115.AXVN01000020_gene107	2.17e-56	175.0	2E0EA@1|root,32W0W@2|Bacteria,1VB0V@1239|Firmicutes,24R8X@186801|Clostridia,3Y20U@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00713	1121115.AXVN01000020_gene108	1.29e-258	709.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,3XYHX@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	xerS	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
NHEHCBFB_00714	1121115.AXVN01000020_gene110	1.56e-98	286.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia,3Y0GI@572511|Blautia	186801|Clostridia	S	Thioesterase-like superfamily	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
NHEHCBFB_00715	1121115.AXVN01000020_gene111	2.25e-236	665.0	COG4942@1|root,COG5263@1|root,COG4942@2|Bacteria,COG5263@2|Bacteria,1VH35@1239|Firmicutes,25KD3@186801|Clostridia,3Y04J@572511|Blautia	186801|Clostridia	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Peptidase_M23
NHEHCBFB_00716	1121115.AXVN01000020_gene112	0.0	939.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,3XZ5I@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NHEHCBFB_00717	1121115.AXVN01000020_gene113	1.58e-153	431.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia	186801|Clostridia	F	COG NOG14451 non supervised orthologous group	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
NHEHCBFB_00718	457412.RSAG_00112	1.67e-219	605.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,3WGKV@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NHEHCBFB_00719	1121115.AXVN01000020_gene115	2.06e-119	341.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3Y0CB@572511|Blautia	186801|Clostridia	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
NHEHCBFB_00720	457412.RSAG_00110	2.07e-261	716.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,3WGPK@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
NHEHCBFB_00721	457412.RSAG_00109	3.03e-179	499.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,3WJ3J@541000|Ruminococcaceae	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
NHEHCBFB_00722	1121115.AXVN01000020_gene118	2.07e-109	320.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,3XZSZ@572511|Blautia	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
NHEHCBFB_00723	1121115.AXVN01000020_gene119	1.14e-161	453.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3XYQJ@572511|Blautia	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
NHEHCBFB_00724	457412.RSAG_00105	0.0	918.0	2DBI9@1|root,2Z9F5@2|Bacteria,1UI10@1239|Firmicutes,25E9Z@186801|Clostridia,3WIPB@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00725	1121115.AXVN01000020_gene121	5.96e-146	411.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3XYNM@572511|Blautia	186801|Clostridia	L	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
NHEHCBFB_00726	1121115.AXVN01000020_gene122	1.23e-80	239.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,3Y07Y@572511|Blautia	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
NHEHCBFB_00727	1121115.AXVN01000020_gene123	3.1e-143	403.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,3XYUN@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
NHEHCBFB_00728	1121115.AXVN01000020_gene124	6.2e-155	434.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,3XZHC@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
NHEHCBFB_00729	1121115.AXVN01000020_gene125	6e-60	185.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,3Y0BI@572511|Blautia	186801|Clostridia	J	RNA-binding protein containing KH domain, possibly ribosomal protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
NHEHCBFB_00730	1121115.AXVN01000020_gene126	1.16e-315	859.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3XYJQ@572511|Blautia	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
NHEHCBFB_00731	1121115.AXVN01000020_gene127	3.52e-62	190.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,3Y06C@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
NHEHCBFB_00732	1121115.AXVN01000020_gene128	1.58e-70	212.0	COG2868@1|root,COG2868@2|Bacteria,1VCNG@1239|Firmicutes,25N63@186801|Clostridia,3Y0KN@572511|Blautia	186801|Clostridia	J	Cysteine protease Prp	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
NHEHCBFB_00733	1121115.AXVN01000020_gene129	3.99e-64	196.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,3Y060@572511|Blautia	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
NHEHCBFB_00734	457412.RSAG_00096	6.23e-286	781.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia,3WICU@541000|Ruminococcaceae	186801|Clostridia	J	TIGRFAM ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
NHEHCBFB_00735	1121115.AXVN01000020_gene131	2.55e-165	462.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,3XZQP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
NHEHCBFB_00736	457412.RSAG_00094	0.0	1256.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,3WHME@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NHEHCBFB_00737	457412.RSAG_00093	0.0	904.0	COG0507@1|root,COG0507@2|Bacteria,1TR2Y@1239|Firmicutes,24B2Q@186801|Clostridia,3WPCY@541000|Ruminococcaceae	186801|Clostridia	L	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
NHEHCBFB_00738	1121115.AXVN01000002_gene1452	9.18e-83	244.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3Y05K@572511|Blautia	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
NHEHCBFB_00739	1121115.AXVN01000002_gene1451	0.0	1143.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia,3XZH5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R10223,R11262	RC00477	ko00000,ko00001,ko01000,ko03016	-	GH13	-	Alpha-amylase,Alpha-amylase_C,DUF1653,Malt_amylase_C
NHEHCBFB_00740	1121115.AXVN01000002_gene1450	6.33e-43	147.0	29V65@1|root,30GJT@2|Bacteria,1UG71@1239|Firmicutes,25NFM@186801|Clostridia,3Y24B@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00741	457412.RSAG_00087	3.56e-259	711.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WIY7@541000|Ruminococcaceae	186801|Clostridia	J	Metallo-beta-lactamase domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
NHEHCBFB_00742	1121115.AXVN01000002_gene1448	7.15e-122	348.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,3Y071@572511|Blautia	186801|Clostridia	I	Thioesterase superfamily	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
NHEHCBFB_00743	1121115.AXVN01000002_gene1447	0.0	917.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3XZ69@572511|Blautia	186801|Clostridia	H	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
NHEHCBFB_00744	457412.RSAG_00084	0.0	1238.0	COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia,3WJGI@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
NHEHCBFB_00745	457412.RSAG_00083	2.76e-306	835.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
NHEHCBFB_00746	457412.RSAG_00082	3.93e-257	711.0	COG4219@1|root,COG4219@2|Bacteria,1V0EY@1239|Firmicutes,24EI3@186801|Clostridia	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
NHEHCBFB_00747	457412.RSAG_00081	3.33e-62	193.0	2FAVS@1|root,3432X@2|Bacteria,1VXAQ@1239|Firmicutes,2520G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00748	1121115.AXVN01000002_gene1442	6.19e-53	166.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
NHEHCBFB_00749	457412.RSAG_00078	4.3e-258	719.0	COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,25E6J@186801|Clostridia,3WH19@541000|Ruminococcaceae	186801|Clostridia	C	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
NHEHCBFB_00750	457412.RSAG_00077	0.0	1122.0	COG5492@1|root,COG5492@2|Bacteria,1UK32@1239|Firmicutes,25FHP@186801|Clostridia	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FIVAR,PBP-Tp47_a,PBP-Tp47_c
NHEHCBFB_00751	1121115.AXVN01000002_gene1439	1.94e-245	674.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,3XZKQ@572511|Blautia	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
NHEHCBFB_00752	457412.RSAG_00075	1.98e-188	523.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3WIWA@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
NHEHCBFB_00753	1121115.AXVN01000002_gene1437	2.33e-91	272.0	COG3976@1|root,COG3976@2|Bacteria,1VT26@1239|Firmicutes,25BMN@186801|Clostridia	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
NHEHCBFB_00754	575593.HMPREF0491_00136	9.7e-272	764.0	COG3525@1|root,COG3525@2|Bacteria,1TRN0@1239|Firmicutes,24CTA@186801|Clostridia,27K23@186928|unclassified Lachnospiraceae	186801|Clostridia	G	hydrolase family 20, catalytic	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20
NHEHCBFB_00755	1121115.AXVN01000012_gene3095	2.25e-186	520.0	COG1940@1|root,COG1940@2|Bacteria,1TP04@1239|Firmicutes,248SD@186801|Clostridia,3XZGU@572511|Blautia	186801|Clostridia	GK	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ROK
NHEHCBFB_00756	658086.HMPREF0994_06434	5.09e-141	420.0	COG1621@1|root,COG1621@2|Bacteria,1VSII@1239|Firmicutes	1239|Firmicutes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00757	478749.BRYFOR_05193	2.22e-188	526.0	COG0329@1|root,COG0329@2|Bacteria,1TQRK@1239|Firmicutes,247ZW@186801|Clostridia	186801|Clostridia	EM	Belongs to the DapA family	nanA	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
NHEHCBFB_00758	397288.C806_02571	6.25e-55	176.0	COG2731@1|root,COG2731@2|Bacteria,1VCI9@1239|Firmicutes,24QNC@186801|Clostridia,27PJ5@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
NHEHCBFB_00759	796940.HMPREF9628_01198	1.02e-154	444.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,25QJ4@186804|Peptostreptococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
NHEHCBFB_00760	1117379.BABA_15312	3.59e-127	374.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NHEHCBFB_00761	1117379.BABA_15317	5.61e-91	279.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,1ZCNS@1386|Bacillus	91061|Bacilli	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
NHEHCBFB_00762	879305.HMPREF9290_1516	3.39e-123	363.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,22GIP@1570339|Peptoniphilaceae	186801|Clostridia	P	ABC transporter, permease protein	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NHEHCBFB_00763	796940.HMPREF9628_01202	2.12e-106	335.0	COG0747@1|root,COG0747@2|Bacteria,1VUKJ@1239|Firmicutes,24EI4@186801|Clostridia	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NHEHCBFB_00764	1121115.AXVN01000012_gene3102	5.82e-174	488.0	COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,24BR4@186801|Clostridia,3Y2BX@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NHEHCBFB_00765	1121115.AXVN01000012_gene3103	9.3e-159	446.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,3XZHW@572511|Blautia	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
NHEHCBFB_00766	457412.RSAG_02744	5.86e-254	697.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,3WH26@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NHEHCBFB_00767	457412.RSAG_02745	7.02e-163	457.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,3WH3N@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
NHEHCBFB_00768	1121115.AXVN01000012_gene3106	1.53e-180	504.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia,3XZRH@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NHEHCBFB_00769	1121115.AXVN01000012_gene3107	0.0	1038.0	COG3534@1|root,COG3534@2|Bacteria,1TRY9@1239|Firmicutes,2497J@186801|Clostridia,3Y1AY@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
NHEHCBFB_00770	1121115.AXVN01000012_gene3108	1.5e-197	548.0	COG0395@1|root,COG0395@2|Bacteria,1TT5G@1239|Firmicutes,249MU@186801|Clostridia,3Y17N@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17236	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
NHEHCBFB_00771	1121115.AXVN01000012_gene3109	1.03e-206	573.0	COG1175@1|root,COG1175@2|Bacteria,1TRSP@1239|Firmicutes,24906@186801|Clostridia,3Y17F@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17235	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
NHEHCBFB_00772	1121115.AXVN01000012_gene3110	0.0	929.0	COG1653@1|root,COG1653@2|Bacteria,1TS9Z@1239|Firmicutes,2490T@186801|Clostridia,3Y14C@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17234	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_00773	1121115.AXVN01000012_gene3111	3.25e-223	615.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,3Y1E9@572511|Blautia	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
NHEHCBFB_00774	1121115.AXVN01000012_gene3112	0.0	1068.0	COG3507@1|root,COG3507@2|Bacteria,1TPHA@1239|Firmicutes,24AKT@186801|Clostridia	186801|Clostridia	G	family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Dockerin_1,GH43_C,Glyco_hydro_43,Laminin_G_3
NHEHCBFB_00775	1121115.AXVN01000012_gene3113	4.21e-245	671.0	COG3940@1|root,COG3940@2|Bacteria,1TRHI@1239|Firmicutes,24AG6@186801|Clostridia,3Y1H0@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
NHEHCBFB_00776	457412.RSAG_02749	3.28e-232	637.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,3WN40@541000|Ruminococcaceae	186801|Clostridia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
NHEHCBFB_00777	1121115.AXVN01000012_gene3115	0.0	1287.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,3Y14N@572511|Blautia	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
NHEHCBFB_00778	1121115.AXVN01000012_gene3116	2.87e-61	187.0	2DPI5@1|root,3326E@2|Bacteria,1VIQZ@1239|Firmicutes,24QSZ@186801|Clostridia,3Y27B@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00779	1121115.AXVN01000012_gene3117	0.0	1057.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia,3Y0TG@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
NHEHCBFB_00780	457412.RSAG_02755	2.18e-211	582.0	COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,24F6M@186801|Clostridia,3WJRY@541000|Ruminococcaceae	186801|Clostridia	S	Putative esterase	-	-	-	ko:K03930	-	-	-	-	ko00000,ko01000	-	CE1	-	Esterase
NHEHCBFB_00781	1235802.C823_05668	1.87e-43	142.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,25X1K@186806|Eubacteriaceae	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
NHEHCBFB_00782	1121115.AXVN01000012_gene3142	6.01e-270	741.0	COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,25CGY@186801|Clostridia,3XZFH@572511|Blautia	186801|Clostridia	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
NHEHCBFB_00783	457412.RSAG_02776	0.0	1232.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TQRN@1239|Firmicutes,247QG@186801|Clostridia,3WH1R@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
NHEHCBFB_00784	457412.RSAG_02777	0.0	1078.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia,3WJUQ@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
NHEHCBFB_00785	457412.RSAG_02778	2.24e-148	417.0	COG2357@1|root,COG2357@2|Bacteria,1UZBZ@1239|Firmicutes,24FD2@186801|Clostridia,3WJCI@541000|Ruminococcaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NHEHCBFB_00786	457412.RSAG_02779	1.55e-272	746.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHER@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NHEHCBFB_00787	457412.RSAG_02780	1e-137	389.0	COG1309@1|root,COG1309@2|Bacteria,1U1ZX@1239|Firmicutes,24ERU@186801|Clostridia,3WRWC@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NHEHCBFB_00788	457412.RSAG_02781	1.86e-89	262.0	COG1895@1|root,COG1895@2|Bacteria,1VG5F@1239|Firmicutes,24RT7@186801|Clostridia,3WMCM@541000|Ruminococcaceae	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
NHEHCBFB_00789	457412.RSAG_02782	8.61e-75	223.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
NHEHCBFB_00790	1121115.AXVN01000103_gene855	4.58e-119	340.0	COG5423@1|root,COG5423@2|Bacteria,1VBHK@1239|Firmicutes,24XGW@186801|Clostridia,3Y0MP@572511|Blautia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NHEHCBFB_00791	457412.RSAG_02784	9.83e-260	712.0	COG3608@1|root,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,3WJ0E@541000|Ruminococcaceae	186801|Clostridia	Q	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
NHEHCBFB_00792	457412.RSAG_02785	1.55e-79	236.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3WK18@541000|Ruminococcaceae	186801|Clostridia	K	regulatory protein, arsR	czrA	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
NHEHCBFB_00793	457412.RSAG_02786	0.0	1174.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WG9Y@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
NHEHCBFB_00794	457412.RSAG_02787	4.15e-46	148.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24QS3@186801|Clostridia,3WKYW@541000|Ruminococcaceae	186801|Clostridia	C	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
NHEHCBFB_00795	457412.RSAG_02788	1.63e-314	858.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_00796	457412.RSAG_04541	1.7e-233	642.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WN6I@541000|Ruminococcaceae	186801|Clostridia	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
NHEHCBFB_00797	457412.RSAG_04542	2.05e-182	508.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WNXH@541000|Ruminococcaceae	186801|Clostridia	EP	ATPases associated with a variety of cellular activities	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NHEHCBFB_00798	457412.RSAG_02790	5.2e-188	523.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WIZI@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15586	ko02010,map02010	M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
NHEHCBFB_00799	457412.RSAG_02791	1.72e-216	598.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WN70@541000|Ruminococcaceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NHEHCBFB_00800	457412.RSAG_02792	0.0	1031.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia	186801|Clostridia	E	Family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NHEHCBFB_00801	457412.RSAG_02793	2.38e-273	749.0	COG1609@1|root,COG1609@2|Bacteria,1UZFZ@1239|Firmicutes,24H13@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00802	457412.RSAG_02794	1.37e-272	744.0	COG3385@1|root,COG3385@2|Bacteria,1UNGW@1239|Firmicutes,24BMP@186801|Clostridia,3WK14@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
NHEHCBFB_00803	457412.RSAG_02795	0.0	932.0	COG1874@1|root,COG1874@2|Bacteria,1TRPS@1239|Firmicutes,24AH9@186801|Clostridia,3WIPR@541000|Ruminococcaceae	186801|Clostridia	G	Domain of unknown function (DUF4832)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,Glyco_hydro_42
NHEHCBFB_00804	457412.RSAG_02796	2.28e-147	416.0	COG1285@1|root,COG1285@2|Bacteria,1TRUW@1239|Firmicutes,248G4@186801|Clostridia,3WHWK@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
NHEHCBFB_00805	457412.RSAG_02797	6.12e-179	498.0	COG5036@1|root,COG5036@2|Bacteria,1TYFN@1239|Firmicutes,24AGZ@186801|Clostridia,3WJCF@541000|Ruminococcaceae	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
NHEHCBFB_00806	457412.RSAG_02798	0.0	1144.0	COG5337@1|root,COG5337@2|Bacteria,1U5H9@1239|Firmicutes,249YX@186801|Clostridia,3WI9H@541000|Ruminococcaceae	186801|Clostridia	M	CotH kinase protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
NHEHCBFB_00807	457412.RSAG_02799	0.0	933.0	COG4267@1|root,COG4267@2|Bacteria,1TRZE@1239|Firmicutes,24EQ7@186801|Clostridia,3WKMX@541000|Ruminococcaceae	186801|Clostridia	S	Putative exopolysaccharide Exporter (EPS-E)	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
NHEHCBFB_00808	457412.RSAG_02800	0.0	973.0	COG0438@1|root,COG0438@2|Bacteria,1TQ8U@1239|Firmicutes,24BAM@186801|Clostridia,3WGGZ@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF3492)	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glycos_transf_1
NHEHCBFB_00809	457412.RSAG_02801	0.0	1203.0	COG4878@1|root,COG4878@2|Bacteria,1TT2Y@1239|Firmicutes,24A4C@186801|Clostridia,3WIQH@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterised protein conserved in bacteria (DUF2194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2194
NHEHCBFB_00810	457412.RSAG_02802	2.82e-203	563.0	28H6W@1|root,2Z7J7@2|Bacteria,1TPV9@1239|Firmicutes,24CD2@186801|Clostridia,3WMQ4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00811	457412.RSAG_02803	0.0	1369.0	COG0451@1|root,COG0451@2|Bacteria,1UYUX@1239|Firmicutes,24CYP@186801|Clostridia,3WKD2@541000|Ruminococcaceae	186801|Clostridia	GM	Domain of unknown function (DUF4118)	-	-	5.1.3.2	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,RmlD_sub_bind
NHEHCBFB_00812	457412.RSAG_02804	0.0	1372.0	COG2234@1|root,COG2234@2|Bacteria,1TRWH@1239|Firmicutes,24BM1@186801|Clostridia,3WI61@541000|Ruminococcaceae	186801|Clostridia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
NHEHCBFB_00813	1121115.AXVN01000103_gene864	9.53e-160	446.0	COG0454@1|root,COG0456@2|Bacteria,1V1I9@1239|Firmicutes,24GXQ@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
NHEHCBFB_00814	1121115.AXVN01000103_gene865	6.46e-83	245.0	COG3682@1|root,COG3682@2|Bacteria,1VEJ8@1239|Firmicutes	1239|Firmicutes	K	repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NHEHCBFB_00815	1121115.AXVN01000103_gene866	1.64e-68	207.0	COG1879@1|root,COG1879@2|Bacteria,1VX4B@1239|Firmicutes,251P0@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00816	457412.RSAG_02436	0.0	1534.0	COG0577@1|root,COG0577@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,3WHE4@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NHEHCBFB_00817	1280698.AUJS01000027_gene2301	1.68e-154	434.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,27W3S@189330|Dorea	186801|Clostridia	V	COG COG1136 ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_00818	457412.RSAG_02434	1.51e-297	812.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NHEHCBFB_00819	483218.BACPEC_01265	2.8e-160	449.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,26A59@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_00820	457412.RSAG_04626	2.26e-49	157.0	COG2265@1|root,COG2265@2|Bacteria,1W04E@1239|Firmicutes	1239|Firmicutes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00821	457412.RSAG_02432	0.0	904.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WHZK@541000|Ruminococcaceae	186801|Clostridia	J	tRNA (Uracil-5-)-methyltransferase	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
NHEHCBFB_00822	1121115.AXVN01000132_gene729	7.81e-29	104.0	2E4IR@1|root,32ZDT@2|Bacteria,1VENP@1239|Firmicutes,24NT8@186801|Clostridia,3Y0CG@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00823	1121115.AXVN01000132_gene730	1.45e-161	452.0	COG0546@1|root,COG0546@2|Bacteria,1UHUD@1239|Firmicutes,25E2T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
NHEHCBFB_00824	457412.RSAG_02429	0.0	1435.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WGKX@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
NHEHCBFB_00825	457412.RSAG_02428	6.93e-140	395.0	COG0789@1|root,COG0789@2|Bacteria,1V1M9@1239|Firmicutes,24FUE@186801|Clostridia,3WS7D@541000|Ruminococcaceae	186801|Clostridia	K	Domain of unknown function (DUF1836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
NHEHCBFB_00826	457412.RSAG_02427	0.0	1509.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,3WGBC@541000|Ruminococcaceae	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
NHEHCBFB_00827	457412.RSAG_02426	2.9e-149	421.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia,3WKI6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
NHEHCBFB_00828	1121115.AXVN01000015_gene3736	4.82e-188	523.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia,3Y0FC@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NHEHCBFB_00829	457412.RSAG_02424	8.19e-212	585.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,3WHPR@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NHEHCBFB_00830	457412.RSAG_02423	1.09e-315	858.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,248X0@186801|Clostridia,3WIWK@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_00831	457412.RSAG_02422	1.27e-217	600.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,3WSMJ@541000|Ruminococcaceae	186801|Clostridia	K	PFAM AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NHEHCBFB_00832	457412.RSAG_02421	0.0	1504.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,3WGBC@541000|Ruminococcaceae	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
NHEHCBFB_00833	457412.RSAG_02420	3.24e-221	609.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,3WSMJ@541000|Ruminococcaceae	186801|Clostridia	K	PFAM AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NHEHCBFB_00834	1121115.AXVN01000015_gene3731	1.66e-244	671.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,247RJ@186801|Clostridia,3XZQB@572511|Blautia	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
NHEHCBFB_00835	585394.RHOM_04395	4.72e-141	400.0	2CJF3@1|root,30DZI@2|Bacteria,1V3V7@1239|Firmicutes,24IC0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00836	1410661.JNKW01000019_gene1970	9.01e-86	254.0	2DMGI@1|root,32RD9@2|Bacteria,1V7HZ@1239|Firmicutes,24IDD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00837	511680.BUTYVIB_02378	3.95e-92	271.0	2AYH2@1|root,31QKF@2|Bacteria,1V93C@1239|Firmicutes,24GEA@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4869)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4869
NHEHCBFB_00838	1280688.AUJB01000012_gene2690	6.36e-60	196.0	COG4271@1|root,COG4271@2|Bacteria,1VBCV@1239|Firmicutes,24PFW@186801|Clostridia	186801|Clostridia	K	Predicted nucleotide-binding protein containing TIR-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR-like
NHEHCBFB_00839	879309.HMPREF9199_0366	0.0	1250.0	COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,4H2IE@909932|Negativicutes	909932|Negativicutes	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
NHEHCBFB_00840	457412.RSAG_02418	0.0	2158.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3WGCC@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NHEHCBFB_00841	1121115.AXVN01000015_gene3729	2.4e-65	199.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,3Y07E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
NHEHCBFB_00842	1121115.AXVN01000015_gene3728	8.11e-173	482.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,3XYKS@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
NHEHCBFB_00843	457412.RSAG_02415	2.16e-263	723.0	COG4214@1|root,COG4214@2|Bacteria,1VU1F@1239|Firmicutes,24XS9@186801|Clostridia,3WGFE@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	xylH	-	-	ko:K10547	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	BPD_transp_2
NHEHCBFB_00844	1121115.AXVN01000015_gene3726	0.0	989.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3Y18A@572511|Blautia	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
NHEHCBFB_00845	1121115.AXVN01000015_gene3725	5.65e-255	699.0	COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,3Y2A7@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10546	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	Peripla_BP_4
NHEHCBFB_00846	1121115.AXVN01000015_gene3724	6.93e-261	715.0	COG4213@1|root,COG4213@2|Bacteria,1UNTA@1239|Firmicutes	1239|Firmicutes	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NHEHCBFB_00847	1121115.AXVN01000015_gene3723	0.0	1040.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,24AFC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NHEHCBFB_00848	457412.RSAG_02410	0.0	929.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia,3WHGB@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
NHEHCBFB_00849	1121115.AXVN01000015_gene3721	2.72e-238	655.0	COG1879@1|root,COG1879@2|Bacteria,1V3FA@1239|Firmicutes,24G5Q@186801|Clostridia,3Y1NU@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NHEHCBFB_00850	1121115.AXVN01000015_gene3720	8.46e-165	462.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24H9B@186801|Clostridia,3XZX4@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
NHEHCBFB_00851	457412.RSAG_02406	2.53e-150	424.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia,3WKI6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
NHEHCBFB_00852	1121115.AXVN01000015_gene3718	2.69e-227	625.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,3XYHJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
NHEHCBFB_00853	1121115.AXVN01000015_gene3717	2.95e-117	335.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia,3Y078@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
NHEHCBFB_00854	457412.RSAG_02403	2.78e-309	843.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,3WGT0@541000|Ruminococcaceae	186801|Clostridia	L	ATPase, AAA family	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
NHEHCBFB_00855	457412.RSAG_02402	3.19e-146	412.0	COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia,3WITW@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NHEHCBFB_00856	1121115.AXVN01000015_gene3708	2.38e-160	450.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,3XZDH@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
NHEHCBFB_00857	1121115.AXVN01000015_gene3707	2.49e-179	499.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,3XZSC@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
NHEHCBFB_00858	1121115.AXVN01000015_gene3706	9.85e-232	640.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,3XYTB@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
NHEHCBFB_00859	1121115.AXVN01000015_gene3705	3.6e-189	528.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,3XYQM@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
NHEHCBFB_00860	1121115.AXVN01000015_gene3704	7.3e-268	734.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,3XZ26@572511|Blautia	186801|Clostridia	E	COG COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
NHEHCBFB_00861	1121115.AXVN01000015_gene3702	1.14e-71	216.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,3Y03U@572511|Blautia	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
NHEHCBFB_00862	457412.RSAG_02397	6.11e-36	122.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,3WMNQ@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
NHEHCBFB_00863	1121115.AXVN01000015_gene3701	1.08e-107	311.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,3XZXW@572511|Blautia	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
NHEHCBFB_00864	1121115.AXVN01000016_gene3645	1.19e-71	215.0	2DP3R@1|root,330E2@2|Bacteria,1VEPT@1239|Firmicutes,24QJB@186801|Clostridia,3Y0IT@572511|Blautia	186801|Clostridia	S	COG NOG16856 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
NHEHCBFB_00865	457412.RSAG_02394	4.37e-266	731.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
NHEHCBFB_00866	457412.RSAG_02393	1.59e-189	535.0	COG1589@1|root,COG1589@2|Bacteria,1V34X@1239|Firmicutes,248RF@186801|Clostridia,3WMQV@541000|Ruminococcaceae	186801|Clostridia	M	COG1589 Cell division septal protein	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
NHEHCBFB_00867	457412.RSAG_02392	1.18e-313	853.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3WG8Y@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA2	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
NHEHCBFB_00868	457412.RSAG_02391	4.12e-253	695.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WHWW@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
NHEHCBFB_00869	457412.RSAG_02390	0.0	900.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3WG85@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
NHEHCBFB_00870	1121115.AXVN01000016_gene3651	4.74e-217	600.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3XZ7U@572511|Blautia	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
NHEHCBFB_00871	457412.RSAG_02388	0.0	1168.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WGI4@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
NHEHCBFB_00872	457412.RSAG_02387	0.0	1373.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WI1C@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein dimerisation domain	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
NHEHCBFB_00873	1121115.AXVN01000016_gene3654	1.11e-125	358.0	2E3U8@1|root,32YRK@2|Bacteria,1VEYB@1239|Firmicutes,24QRX@186801|Clostridia,3Y079@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
NHEHCBFB_00874	1121115.AXVN01000016_gene3655	1.55e-223	616.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,3XYP8@572511|Blautia	186801|Clostridia	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
NHEHCBFB_00875	457412.RSAG_02384	2.79e-102	295.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,3WJCZ@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
NHEHCBFB_00876	457412.RSAG_02383	6.2e-241	662.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,3WH7A@541000|Ruminococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
NHEHCBFB_00877	1121115.AXVN01000016_gene3658	5.7e-260	712.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,3XZ6D@572511|Blautia	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
NHEHCBFB_00878	457412.RSAG_02381	9.98e-161	451.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3WJUT@541000|Ruminococcaceae	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
NHEHCBFB_00879	1121115.AXVN01000016_gene3670	2.81e-157	441.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3XZY7@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
NHEHCBFB_00880	457412.RSAG_02379	3.21e-211	583.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,3WGGY@541000|Ruminococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
NHEHCBFB_00881	457412.RSAG_02378	0.0	1293.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WGK8@541000|Ruminococcaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
NHEHCBFB_00882	457412.RSAG_02377	1.14e-173	484.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,3WJ4X@541000|Ruminococcaceae	186801|Clostridia	T	serine threonine protein phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
NHEHCBFB_00883	1121115.AXVN01000016_gene3674	7.37e-251	688.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3XZJW@572511|Blautia	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
NHEHCBFB_00884	457412.RSAG_02375	0.0	899.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,3WGKM@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
NHEHCBFB_00885	457412.RSAG_02374	8.48e-147	415.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,3WICN@541000|Ruminococcaceae	186801|Clostridia	S	zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
NHEHCBFB_00886	457412.RSAG_02373	1.09e-225	622.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,3WGPQ@541000|Ruminococcaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
NHEHCBFB_00887	1121115.AXVN01000016_gene3678	3.4e-108	311.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,3Y03J@572511|Blautia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
NHEHCBFB_00888	1121115.AXVN01000016_gene3679	0.0	1430.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3XYQI@572511|Blautia	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
NHEHCBFB_00889	1121115.AXVN01000016_gene3680	0.0	970.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3XYZ0@572511|Blautia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NHEHCBFB_00890	1121115.AXVN01000016_gene3681	0.0	1014.0	2EX8G@1|root,33QJ9@2|Bacteria,1VTVN@1239|Firmicutes,25FHM@186801|Clostridia,3Y0FY@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00891	457412.RSAG_02368	1.72e-215	595.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,3WHV4@541000|Ruminococcaceae	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NHEHCBFB_00892	1121115.AXVN01000016_gene3683	0.0	1450.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3XYTU@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
NHEHCBFB_00893	457412.RSAG_02366	1.62e-89	276.0	2EYFJ@1|root,33RPG@2|Bacteria,1VSB2@1239|Firmicutes,24ZFW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00894	1121115.AXVN01000016_gene3686	1.59e-244	671.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia,3XYZ8@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
NHEHCBFB_00895	457412.RSAG_02364	1.82e-97	283.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia,3WKBA@541000|Ruminococcaceae	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
NHEHCBFB_00896	457412.RSAG_02363	1.04e-219	607.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,24A3I@186801|Clostridia,3WND9@541000|Ruminococcaceae	186801|Clostridia	S	Sodium Bile acid symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SBF
NHEHCBFB_00897	457412.RSAG_02362	1.62e-172	481.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3WGJA@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type polar amino acid transport system ATPase component	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
NHEHCBFB_00898	1121115.AXVN01000016_gene3690	1.22e-157	443.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,3XZT5@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
NHEHCBFB_00899	457412.RSAG_04631	1.32e-179	501.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,3WIYH@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	artP	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NHEHCBFB_00900	1121115.AXVN01000016_gene3692	3.36e-205	567.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3XZFN@572511|Blautia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
NHEHCBFB_00901	1121115.AXVN01000016_gene3693	1.17e-58	182.0	COG4392@1|root,COG4392@2|Bacteria,1VAKN@1239|Firmicutes,24N0I@186801|Clostridia,3Y0E3@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
NHEHCBFB_00902	1121115.AXVN01000016_gene3694	2.35e-158	445.0	COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,3XZSK@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.99	ygaZ	-	-	-	-	-	-	-	-	-	-	-	AzlC
NHEHCBFB_00903	457412.RSAG_02357	2.03e-210	585.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NHEHCBFB_00904	1121115.AXVN01000016_gene3696	6.37e-102	294.0	COG0735@1|root,COG0735@2|Bacteria,1V970@1239|Firmicutes,25MW0@186801|Clostridia,3Y26V@572511|Blautia	186801|Clostridia	P	Ferric uptake regulator family	-	-	-	-	-	-	-	-	-	-	-	-	FUR
NHEHCBFB_00905	457412.RSAG_02355	1.13e-191	533.0	2C6CR@1|root,2Z7X4@2|Bacteria,1UY2Y@1239|Firmicutes,24EJP@186801|Clostridia,3WIK3@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_2
NHEHCBFB_00906	1121115.AXVN01000036_gene2404	7.8e-315	857.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NHEHCBFB_00907	1121115.AXVN01000036_gene2405	7.88e-269	734.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,3XZBE@572511|Blautia	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	trmU	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
NHEHCBFB_00908	457412.RSAG_02352	2.11e-220	608.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3WG9Z@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NHEHCBFB_00909	1121115.AXVN01000036_gene2407	4.8e-99	287.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3Y0EE@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NHEHCBFB_00910	1121115.AXVN01000036_gene2408	1.97e-96	281.0	COG4747@1|root,COG4747@2|Bacteria,1V8ZY@1239|Firmicutes,24NAM@186801|Clostridia,3Y0M9@572511|Blautia	186801|Clostridia	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00911	457412.RSAG_02349	0.0	1610.0	COG0695@1|root,COG1328@1|root,COG0695@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3WGUQ@541000|Ruminococcaceae	186801|Clostridia	F	TIGRFAM anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,Glutaredoxin,NRDD
NHEHCBFB_00912	1121115.AXVN01000036_gene2410	1.25e-284	779.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,3XZ8M@572511|Blautia	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
NHEHCBFB_00913	457412.RSAG_02347	6.61e-235	648.0	COG0457@1|root,COG0457@2|Bacteria,1V6VP@1239|Firmicutes,258AK@186801|Clostridia,3WMBI@541000|Ruminococcaceae	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
NHEHCBFB_00914	1121115.AXVN01000036_gene2412	0.0	879.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3XYSV@572511|Blautia	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NHEHCBFB_00915	457412.RSAG_02345	4.24e-218	602.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3WHDJ@541000|Ruminococcaceae	186801|Clostridia	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
NHEHCBFB_00916	1121115.AXVN01000036_gene2414	1.09e-249	686.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3XYXD@572511|Blautia	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
NHEHCBFB_00917	1121115.AXVN01000036_gene2415	2.41e-232	639.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,3XZ9I@572511|Blautia	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
NHEHCBFB_00918	1121115.AXVN01000036_gene2416	7.04e-221	610.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,3XYUQ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
NHEHCBFB_00919	1121115.AXVN01000036_gene2417	1.02e-46	149.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3Y0G4@572511|Blautia	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
NHEHCBFB_00920	457412.RSAG_02341	0.0	897.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia,3WGZQ@541000|Ruminococcaceae	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
NHEHCBFB_00921	457412.RSAG_02340	3.75e-109	315.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,24HSW@186801|Clostridia,3WJEQ@541000|Ruminococcaceae	186801|Clostridia	S	small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
NHEHCBFB_00922	1121115.AXVN01000036_gene2428	5.7e-262	716.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,3XYHE@572511|Blautia	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NHEHCBFB_00923	457412.RSAG_02338	0.0	1299.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3WGVM@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
NHEHCBFB_00924	1121115.AXVN01000036_gene2432	0.0	890.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3Y0CH@572511|Blautia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_00925	1121115.AXVN01000036_gene2433	2.44e-211	584.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia,3Y17Y@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NHEHCBFB_00926	1121115.AXVN01000036_gene2434	3.53e-200	555.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,3Y023@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NHEHCBFB_00927	1121115.AXVN01000011_gene3447	1.78e-208	576.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,3XYTN@572511|Blautia	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
NHEHCBFB_00928	1121115.AXVN01000011_gene3446	2.85e-153	429.0	COG4656@1|root,COG4656@2|Bacteria,1TS9H@1239|Firmicutes,24DQ7@186801|Clostridia,3XYYU@572511|Blautia	186801|Clostridia	C	Methylene-tetrahydrofolate reductase C terminal	metV	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS18525	MTHFR_C
NHEHCBFB_00929	457412.RSAG_02335	0.0	1316.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,MTHFR_C,RnfC_N,SLBB
NHEHCBFB_00931	457412.RSAG_02332	2.82e-206	571.0	2BB5X@1|root,324NG@2|Bacteria,1V7KI@1239|Firmicutes,24MCT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00932	457412.RSAG_02331	8.11e-145	408.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,24E7M@186801|Clostridia,3WJQ7@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K07694	ko02020,map02020	M00480	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
NHEHCBFB_00933	457412.RSAG_02330	1.97e-311	851.0	COG4585@1|root,COG4585@2|Bacteria,1V4GJ@1239|Firmicutes,24M3N@186801|Clostridia,3WJCM@541000|Ruminococcaceae	186801|Clostridia	T	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00934	457412.RSAG_02329	0.0	1079.0	2DBJI@1|root,2Z9M2@2|Bacteria,1V4CA@1239|Firmicutes,24IGG@186801|Clostridia,3WIQJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
NHEHCBFB_00935	457412.RSAG_02328	3.03e-149	433.0	2C1YG@1|root,30J7S@2|Bacteria,1TVA7@1239|Firmicutes,25A6I@186801|Clostridia,3WR8T@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00936	457412.RSAG_02327	4.78e-185	516.0	2F1N0@1|root,33UNB@2|Bacteria,1VUUW@1239|Firmicutes,250GG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00937	1121115.AXVN01000011_gene3443	0.0	1617.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3Y135@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
NHEHCBFB_00938	1121115.AXVN01000011_gene3442	6.07e-189	526.0	COG0834@1|root,COG0834@2|Bacteria,1VTCR@1239|Firmicutes,24YIS@186801|Clostridia	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
NHEHCBFB_00939	457412.RSAG_02325	1.02e-168	471.0	COG1489@1|root,COG1489@2|Bacteria,1VTYF@1239|Firmicutes,25E56@186801|Clostridia,3WS62@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
NHEHCBFB_00940	457412.RSAG_02313	0.0	1114.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
NHEHCBFB_00941	1121115.AXVN01000131_gene734	2.87e-36	130.0	COG0583@1|root,COG0583@2|Bacteria,1TSNI@1239|Firmicutes,249QS@186801|Clostridia,3XZUG@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_00942	457412.RSAG_02614	1.09e-95	279.0	2BVD7@1|root,32QT8@2|Bacteria,1V6S8@1239|Firmicutes,24JJP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00943	180332.JTGN01000006_gene3390	1.11e-36	137.0	COG2274@1|root,COG2274@2|Bacteria,1TRMR@1239|Firmicutes,248Z2@186801|Clostridia	186801|Clostridia	V	bacteriocin system ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
NHEHCBFB_00945	1121115.AXVN01000131_gene734	3.32e-203	563.0	COG0583@1|root,COG0583@2|Bacteria,1TSNI@1239|Firmicutes,249QS@186801|Clostridia,3XZUG@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_00946	1121115.AXVN01000131_gene735	1.5e-226	623.0	COG2221@1|root,COG2221@2|Bacteria,1UI1A@1239|Firmicutes,25EAA@186801|Clostridia,3Y28E@572511|Blautia	186801|Clostridia	C	Nitrite and sulphite reductase 4Fe-4S domain	dsvA	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C,Fer4,Fer4_10,NIR_SIR,NIR_SIR_ferr
NHEHCBFB_00947	1121115.AXVN01000131_gene736	0.0	1061.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,3Y0FH@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score 9.99	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
NHEHCBFB_00948	457412.RSAG_02307	2.99e-65	199.0	2BQ4H@1|root,32IYV@2|Bacteria,1US27@1239|Firmicutes,25A0K@186801|Clostridia,3WQZK@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00949	1121115.AXVN01000131_gene738	7.66e-180	501.0	2E509@1|root,32ZTU@2|Bacteria,1VB4U@1239|Firmicutes,249Y2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00950	457412.RSAG_02305	3.52e-118	338.0	COG1595@1|root,COG1595@2|Bacteria,1VGKP@1239|Firmicutes,24RUX@186801|Clostridia,3WKQD@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NHEHCBFB_00951	1121115.AXVN01000038_gene3346	6.8e-104	300.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia,3Y0WP@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
NHEHCBFB_00952	1121115.AXVN01000038_gene3345	5.39e-224	618.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,25D2S@186801|Clostridia,3Y1VG@572511|Blautia	186801|Clostridia	K	Putative sugar-binding domain	sorC	-	-	-	-	-	-	-	-	-	-	-	HTH_24,Sugar-bind
NHEHCBFB_00953	1121115.AXVN01000038_gene3344	2.14e-170	475.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,3XYMH@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	ulaF	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
NHEHCBFB_00954	1121115.AXVN01000038_gene3343	3.98e-264	721.0	28IPH@1|root,2Z8PG@2|Bacteria,1TREB@1239|Firmicutes,248QM@186801|Clostridia,3Y18D@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00955	1121115.AXVN01000038_gene3342	0.0	899.0	COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,247MD@186801|Clostridia,3Y0FE@572511|Blautia	186801|Clostridia	S	PTS system sugar-specific permease component	-	-	-	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.7.1	-	-	EIIC-GAT
NHEHCBFB_00956	1121115.AXVN01000038_gene3341	0.0	1000.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3XZDA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.17,2.7.1.30	ko:K00854,ko:K00864	ko00040,ko00561,ko01100,ko03320,ko04626,map00040,map00561,map01100,map03320,map04626	M00014	R00847,R01639	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
NHEHCBFB_00957	1121115.AXVN01000038_gene3340	2.15e-290	790.0	COG2220@1|root,COG2220@2|Bacteria,1TSFV@1239|Firmicutes,249MG@186801|Clostridia,3Y1A5@572511|Blautia	186801|Clostridia	S	Beta-lactamase superfamily domain	ulaG	-	-	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	M00550	R07677	RC02793	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactamase_B_2,Lactamase_B_3
NHEHCBFB_00958	1121115.AXVN01000038_gene3339	2.84e-204	565.0	COG3623@1|root,COG3623@2|Bacteria,1TSMS@1239|Firmicutes,247T6@186801|Clostridia,3Y1CM@572511|Blautia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	ulaE	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
NHEHCBFB_00959	1121115.AXVN01000038_gene3338	5.97e-92	268.0	2E2GC@1|root,32XKF@2|Bacteria,1VCKF@1239|Firmicutes,24QFN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00960	1121115.AXVN01000038_gene3337	8.94e-177	493.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,3XYRK@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
NHEHCBFB_00961	1121115.AXVN01000038_gene3336	1.19e-93	272.0	COG4357@1|root,COG4357@2|Bacteria,1VB64@1239|Firmicutes,24ZZZ@186801|Clostridia	186801|Clostridia	S	CHY zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHY
NHEHCBFB_00962	1121115.AXVN01000038_gene3335	1.35e-127	363.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,3Y025@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
NHEHCBFB_00963	1121115.AXVN01000038_gene3328	0.0	1047.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NHEHCBFB_00964	457412.RSAG_02293	1.23e-34	122.0	COG1247@1|root,COG1247@2|Bacteria,1V3XH@1239|Firmicutes,24HCN@186801|Clostridia,3WJJI@541000|Ruminococcaceae	186801|Clostridia	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NHEHCBFB_00965	1121115.AXVN01000038_gene3326	1.62e-192	534.0	COG0566@1|root,COG0566@2|Bacteria,1TSUW@1239|Firmicutes,24ACK@186801|Clostridia,3XYTE@572511|Blautia	186801|Clostridia	H	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
NHEHCBFB_00966	457412.RSAG_02288	6.98e-113	325.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,24JAA@186801|Clostridia,3WS5T@541000|Ruminococcaceae	186801|Clostridia	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K13531	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
NHEHCBFB_00967	457412.RSAG_02287	4.02e-299	817.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia,3WH7U@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_00968	1121115.AXVN01000038_gene3324	0.0	899.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3XZU5@572511|Blautia	186801|Clostridia	G	COG COG2211 Na melibiose symporter and related transporters	gph	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2
NHEHCBFB_00969	1121115.AXVN01000038_gene3323	1.88e-251	689.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,3Y04Y@572511|Blautia	186801|Clostridia	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
NHEHCBFB_00970	457412.RSAG_02284	3.89e-265	726.0	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,24A9E@186801|Clostridia,3WH5F@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
NHEHCBFB_00971	411459.RUMOBE_03451	4.18e-303	829.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,2481G@186801|Clostridia,3XYVW@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_00972	1235792.C808_03815	2.66e-193	550.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,27I7H@186928|unclassified Lachnospiraceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_00973	457412.RSAG_02279	2.24e-140	397.0	COG0494@1|root,COG0494@2|Bacteria,1V27D@1239|Firmicutes,24GB6@186801|Clostridia,3WRQY@541000|Ruminococcaceae	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
NHEHCBFB_00974	457412.RSAG_02276	1.1e-139	395.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,3WI1Y@541000|Ruminococcaceae	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
NHEHCBFB_00975	457412.RSAG_02275	8.86e-133	377.0	2EJGK@1|root,33D7H@2|Bacteria,1VMPJ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00978	457412.RSAG_02272	5.94e-91	267.0	2DNMV@1|root,32Y6A@2|Bacteria,1VFC4@1239|Firmicutes,24QMI@186801|Clostridia,3WMGA@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00979	1121115.AXVN01000175_gene3963	2.71e-191	535.0	COG3103@1|root,COG3103@2|Bacteria,1VAHD@1239|Firmicutes,24NRJ@186801|Clostridia,3Y237@572511|Blautia	186801|Clostridia	T	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
NHEHCBFB_00983	476272.RUMHYD_03148	6.15e-30	124.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_24,TIR_2
NHEHCBFB_00985	1280673.AUJJ01000010_gene2495	7.08e-28	104.0	COG1813@1|root,COG1813@2|Bacteria,1UPCZ@1239|Firmicutes,25HCQ@186801|Clostridia,4BZXF@830|Butyrivibrio	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_00987	546269.HMPREF0389_01555	7.56e-111	333.0	2DBTR@1|root,2ZB0I@2|Bacteria,1V1SY@1239|Firmicutes,24C1D@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00988	523794.Lebu_1192	7e-39	130.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
NHEHCBFB_00989	1122212.AULO01000011_gene591	2.3e-108	334.0	28IDW@1|root,2Z8G1@2|Bacteria,1R6ZA@1224|Proteobacteria,1RYDH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00990	33035.JPJF01000049_gene669	1.68e-36	125.0	2DQDV@1|root,33675@2|Bacteria,1VITX@1239|Firmicutes,24S3U@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NHEHCBFB_00991	1301100.HG529329_gene4437	1.51e-46	170.0	COG0515@1|root,COG0515@2|Bacteria,1V7U3@1239|Firmicutes,25AZB@186801|Clostridia,36W6R@31979|Clostridiaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
NHEHCBFB_00992	353496.LBU_1763	3.06e-10	61.6	2E529@1|root,32ZVG@2|Bacteria,1VJ79@1239|Firmicutes,4HRTV@91061|Bacilli,3FBN0@33958|Lactobacillaceae	91061|Bacilli	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_00993	411459.RUMOBE_03918	0.0	1028.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3XZ6T@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
NHEHCBFB_00994	1410628.JNKS01000005_gene1096	3.28e-149	425.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A3D@186801|Clostridia,27IZM@186928|unclassified Lachnospiraceae	186801|Clostridia	U	overlaps another CDS with the same product name	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NHEHCBFB_00995	1410628.JNKS01000005_gene1095	4.07e-150	430.0	COG1175@1|root,COG1175@2|Bacteria,1TQB1@1239|Firmicutes,25C4P@186801|Clostridia,27JHD@186928|unclassified Lachnospiraceae	186801|Clostridia	U	overlaps another CDS with the same product name	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NHEHCBFB_00996	1304866.K413DRAFT_2054	9.55e-160	464.0	COG1653@1|root,COG1653@2|Bacteria,1TQJE@1239|Firmicutes,2496C@186801|Clostridia,36FES@31979|Clostridiaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_00997	411459.RUMOBE_03916	5.56e-197	551.0	COG1609@1|root,COG1609@2|Bacteria,1UM0E@1239|Firmicutes,25B2H@186801|Clostridia,3Y2DY@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NHEHCBFB_00998	1121115.AXVN01000028_gene226	2e-52	164.0	2DKC3@1|root,30954@2|Bacteria,1U4FV@1239|Firmicutes,258BV@186801|Clostridia,3Y1WH@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
NHEHCBFB_00999	1121115.AXVN01000028_gene225	5.69e-40	132.0	COG0425@1|root,COG0425@2|Bacteria,1VKDK@1239|Firmicutes,24RK7@186801|Clostridia,3Y1ZM@572511|Blautia	186801|Clostridia	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
NHEHCBFB_01000	1121115.AXVN01000028_gene224	3.25e-252	692.0	COG2391@1|root,COG2391@2|Bacteria,1TPWG@1239|Firmicutes,249KU@186801|Clostridia,3Y10Q@572511|Blautia	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
NHEHCBFB_01001	457412.RSAG_02261	1.11e-284	777.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,3WH06@541000|Ruminococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
NHEHCBFB_01002	457412.RSAG_02260	6.97e-209	578.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,3WRR9@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_01003	1121115.AXVN01000028_gene221	0.0	1779.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3XZE8@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Peptidase_S51,Response_reg
NHEHCBFB_01005	126957.SMAR004755-PA	8.67e-09	66.6	KOG0032@1|root,KOG0032@2759|Eukaryota,38GFU@33154|Opisthokonta,3BAQ1@33208|Metazoa,3CY7G@33213|Bilateria,41VIP@6656|Arthropoda	33208|Metazoa	T	Death domain	DAPK1	GO:0000149,GO:0000166,GO:0001952,GO:0002376,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004683,GO:0005488,GO:0005515,GO:0005516,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005856,GO:0005884,GO:0005886,GO:0006355,GO:0006417,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006937,GO:0006940,GO:0006950,GO:0006952,GO:0006955,GO:0006979,GO:0007088,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007346,GO:0007399,GO:0008022,GO:0008134,GO:0008140,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0008360,GO:0008625,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010469,GO:0010506,GO:0010508,GO:0010556,GO:0010558,GO:0010564,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010810,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0015629,GO:0016020,GO:0016301,GO:0016310,GO:0016604,GO:0016605,GO:0016740,GO:0016772,GO:0016773,GO:0017016,GO:0017048,GO:0017075,GO:0017076,GO:0017148,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0019904,GO:0019905,GO:0022008,GO:0022603,GO:0022604,GO:0022898,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030111,GO:0030154,GO:0030155,GO:0030162,GO:0030177,GO:0030182,GO:0030275,GO:0030334,GO:0030335,GO:0030554,GO:0031267,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031329,GO:0031331,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032270,GO:0032409,GO:0032412,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032956,GO:0032970,GO:0033043,GO:0033194,GO:0033554,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034599,GO:0034762,GO:0034765,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0040012,GO:0040017,GO:0042221,GO:0042802,GO:0042803,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043269,GO:0043280,GO:0043281,GO:0043412,GO:0043519,GO:0043522,GO:0044057,GO:0044087,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045087,GO:0045121,GO:0045862,GO:0046777,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051020,GO:0051049,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051270,GO:0051272,GO:0051336,GO:0051345,GO:0051493,GO:0051716,GO:0051726,GO:0051783,GO:0051893,GO:0052547,GO:0052548,GO:0060255,GO:0060548,GO:0060828,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070887,GO:0071310,GO:0071345,GO:0071346,GO:0071447,GO:0071704,GO:0071944,GO:0080090,GO:0090109,GO:0090257,GO:0090263,GO:0097159,GO:0097190,GO:0097191,GO:0097367,GO:0098589,GO:0098805,GO:0098857,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099601,GO:0140096,GO:1900449,GO:1901265,GO:1901363,GO:1901564,GO:1901700,GO:1901701,GO:1901888,GO:1902041,GO:1902042,GO:1903391,GO:1903506,GO:1904062,GO:2000112,GO:2000113,GO:2000116,GO:2000145,GO:2000147,GO:2000249,GO:2000310,GO:2001056,GO:2001141,GO:2001233,GO:2001234,GO:2001235,GO:2001236,GO:2001237,GO:2001238,GO:2001239,GO:2001241,GO:2001257	2.7.11.1	ko:K08803	ko04140,ko05200,ko05219,map04140,map05200,map05219	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	Ank_2,Ank_4,Ank_5,Death,Pkinase
NHEHCBFB_01007	457412.RSAG_02257	4.48e-173	483.0	COG0842@1|root,COG0842@2|Bacteria,1UYEB@1239|Firmicutes,24BUQ@186801|Clostridia,3WMU4@541000|Ruminococcaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
NHEHCBFB_01008	1121115.AXVN01000028_gene219	1.23e-193	538.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,3Y07P@572511|Blautia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	nodI	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_01009	1121115.AXVN01000028_gene218	1.05e-156	440.0	COG2243@1|root,COG2243@2|Bacteria,1TP87@1239|Firmicutes,249DM@186801|Clostridia,3XYXX@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NHEHCBFB_01010	1121115.AXVN01000028_gene217	2.94e-118	338.0	COG0614@1|root,COG0614@2|Bacteria,1V6JK@1239|Firmicutes,24KN9@186801|Clostridia,3Y12K@572511|Blautia	186801|Clostridia	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01011	1121115.AXVN01000028_gene216	0.0	942.0	COG3669@1|root,COG3669@2|Bacteria,1TQH2@1239|Firmicutes,24B8Y@186801|Clostridia,3XYWJ@572511|Blautia	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
NHEHCBFB_01012	457412.RSAG_02252	0.0	1647.0	COG1305@1|root,COG1305@2|Bacteria,1TQGN@1239|Firmicutes,249YH@186801|Clostridia,3WMZ2@541000|Ruminococcaceae	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NHEHCBFB_01013	457412.RSAG_02251	1.76e-177	494.0	COG3142@1|root,COG3142@2|Bacteria,1UYI8@1239|Firmicutes,247QB@186801|Clostridia,3WIQQ@541000|Ruminococcaceae	186801|Clostridia	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
NHEHCBFB_01014	457412.RSAG_02250	4.25e-175	489.0	COG1349@1|root,COG1349@2|Bacteria,1TSU1@1239|Firmicutes,25C4E@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, DeoR	-	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
NHEHCBFB_01015	457412.RSAG_04635	6.95e-238	653.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WH83@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NHEHCBFB_01016	457412.RSAG_02249	2.42e-236	650.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WGTC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NHEHCBFB_01017	457412.RSAG_02248	9.03e-185	517.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WJDM@541000|Ruminococcaceae	186801|Clostridia	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034,ko:K13891	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	BPD_transp_1,OppC_N
NHEHCBFB_01018	1121115.AXVN01000028_gene209	3.56e-206	572.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3Y02S@572511|Blautia	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13890	ko02010,map02010	M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.11	-	-	BPD_transp_1
NHEHCBFB_01019	457412.RSAG_02246	0.0	1065.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3WISX@541000|Ruminococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13889	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	SBP_bac_5
NHEHCBFB_01020	457412.RSAG_02245	4.31e-197	547.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,3WHGA@541000|Ruminococcaceae	186801|Clostridia	M	Mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
NHEHCBFB_01021	1121115.AXVN01000028_gene206	5.58e-60	185.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,3Y0K2@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
NHEHCBFB_01022	1121115.AXVN01000028_gene205	1.45e-46	149.0	COG1925@1|root,COG1925@2|Bacteria,1URTV@1239|Firmicutes,259R8@186801|Clostridia,3Y261@572511|Blautia	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01023	1121115.AXVN01000028_gene204	2.01e-212	587.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3XZVT@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_01024	457412.RSAG_02241	0.0	1371.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,3WGWI@541000|Ruminococcaceae	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
NHEHCBFB_01025	457412.RSAG_02240	1.01e-309	843.0	COG2234@1|root,COG2234@2|Bacteria,1UFM1@1239|Firmicutes	1239|Firmicutes	S	Aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
NHEHCBFB_01026	457412.RSAG_02239	5.92e-206	574.0	COG5523@1|root,COG5523@2|Bacteria,1TTE0@1239|Firmicutes,25M7C@186801|Clostridia,3WMQF@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
NHEHCBFB_01027	1121115.AXVN01000028_gene200	5.71e-281	769.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3XYJN@572511|Blautia	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
NHEHCBFB_01028	1121115.AXVN01000028_gene199	2.37e-290	793.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3XYWS@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
NHEHCBFB_01029	1121115.AXVN01000028_gene198	7.24e-102	295.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia,3XZTJ@572511|Blautia	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
NHEHCBFB_01030	1121115.AXVN01000028_gene197	3.29e-234	644.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,3XZ5R@572511|Blautia	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
NHEHCBFB_01031	1121115.AXVN01000028_gene195	2.61e-201	557.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24B81@186801|Clostridia,3XZ57@572511|Blautia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF_2	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
NHEHCBFB_01032	457412.RSAG_02233	6.21e-206	569.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ8Y@1239|Firmicutes,248SM@186801|Clostridia,3WJQB@541000|Ruminococcaceae	186801|Clostridia	K	PFAM AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NHEHCBFB_01033	457412.RSAG_02232	0.0	967.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WHBC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NHEHCBFB_01034	457412.RSAG_02231	0.0	1659.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3WGPN@541000|Ruminococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
NHEHCBFB_01035	1121115.AXVN01000125_gene3811	0.0	1004.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3XYYI@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
NHEHCBFB_01036	1121115.AXVN01000125_gene3810	6.26e-118	338.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3XZRY@572511|Blautia	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
NHEHCBFB_01037	1121115.AXVN01000125_gene3809	2.06e-184	512.0	COG0106@1|root,COG0106@2|Bacteria,1TPIN@1239|Firmicutes,249HJ@186801|Clostridia,3XYK1@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisA	-	-	-	-	-	-	-	-	-	-	-	His_biosynth
NHEHCBFB_01038	1121115.AXVN01000125_gene3808	9.24e-28	108.0	2EYMV@1|root,33RVF@2|Bacteria,1VSPB@1239|Firmicutes,24XPM@186801|Clostridia,3Y0UE@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01039	457412.RSAG_02225	3.62e-272	748.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WGET@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NHEHCBFB_01040	1121115.AXVN01000125_gene3806	1.05e-176	493.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,3XZD1@572511|Blautia	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
NHEHCBFB_01041	1121115.AXVN01000125_gene3805	1.52e-207	574.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,3XZIM@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
NHEHCBFB_01042	457412.RSAG_02222	4.24e-109	314.0	COG2109@1|root,COG2109@2|Bacteria,1V82Z@1239|Firmicutes,24J8J@186801|Clostridia	186801|Clostridia	H	Psort location Cytoplasmic, score	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
NHEHCBFB_01043	1121115.AXVN01000037_gene3238	1.25e-148	418.0	COG0629@1|root,COG0629@2|Bacteria,1TRWZ@1239|Firmicutes,248UD@186801|Clostridia,3XZI3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ssb1	-	-	-	-	-	-	-	-	-	-	-	SSB
NHEHCBFB_01044	1121115.AXVN01000037_gene3239	0.0	1185.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3XYY0@572511|Blautia	186801|Clostridia	T	GTP-binding protein TypA BipA homolog	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
NHEHCBFB_01045	1121115.AXVN01000037_gene3240	0.0	1732.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
NHEHCBFB_01046	1121115.AXVN01000037_gene3241	3e-255	701.0	COG3347@1|root,COG3347@2|Bacteria,1TQB8@1239|Firmicutes,25BHR@186801|Clostridia,3Y16D@572511|Blautia	186801|Clostridia	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
NHEHCBFB_01047	1121115.AXVN01000037_gene3242	0.0	1057.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3Y0X8@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
NHEHCBFB_01048	457412.RSAG_02216	1.08e-247	681.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,3WHMJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
NHEHCBFB_01049	1121115.AXVN01000037_gene3244	7.82e-118	337.0	COG0716@1|root,COG0716@2|Bacteria,1VB6B@1239|Firmicutes,24GQN@186801|Clostridia,3Y2CS@572511|Blautia	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3
NHEHCBFB_01050	457412.RSAG_02214	1.01e-77	232.0	2CFUE@1|root,33V7A@2|Bacteria,1VUR9@1239|Firmicutes,250BS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01051	457412.RSAG_01616	0.0	1181.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3WI2B@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,Glyco_hydro_31
NHEHCBFB_01052	33035.JPJF01000037_gene2974	8.82e-153	434.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia,3Y0HM@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NHEHCBFB_01053	33035.JPJF01000037_gene2973	3.55e-177	506.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,3Y1I8@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
NHEHCBFB_01054	33035.JPJF01000037_gene2972	8.86e-171	492.0	COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,25MFS@186801|Clostridia,3Y1U2@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NHEHCBFB_01055	33035.JPJF01000037_gene2971	1.29e-97	299.0	COG1609@1|root,COG1609@2|Bacteria,1TS5M@1239|Firmicutes,24AWP@186801|Clostridia,3Y018@572511|Blautia	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NHEHCBFB_01056	1121115.AXVN01000037_gene3246	3.13e-86	254.0	COG0346@1|root,COG0346@2|Bacteria,1V7XP@1239|Firmicutes,24KYI@186801|Clostridia,3Y0HK@572511|Blautia	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
NHEHCBFB_01057	1121115.AXVN01000037_gene3247	0.0	1067.0	COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,247TG@186801|Clostridia,3XYQY@572511|Blautia	186801|Clostridia	G	Mannitol dehydrogenase Rossmann domain	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
NHEHCBFB_01058	457412.RSAG_02212	3.95e-273	747.0	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,24A9E@186801|Clostridia,3WICI@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
NHEHCBFB_01059	457412.RSAG_02211	9.51e-239	656.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,3WM8X@541000|Ruminococcaceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
NHEHCBFB_01060	457412.RSAG_02210	4.78e-55	171.0	2DWC0@1|root,33ZIT@2|Bacteria,1VY40@1239|Firmicutes,252ED@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01061	1121115.AXVN01000037_gene3251	0.0	1132.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3Y19R@572511|Blautia	186801|Clostridia	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
NHEHCBFB_01063	1121115.AXVN01000037_gene3252	8.36e-312	851.0	COG1070@1|root,COG1070@2|Bacteria,1TSEJ@1239|Firmicutes,24AT3@186801|Clostridia,3Y1CK@572511|Blautia	186801|Clostridia	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NHEHCBFB_01064	1121115.AXVN01000037_gene3253	3.08e-286	781.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,3XZCR@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NHEHCBFB_01065	457412.RSAG_02206	7.25e-88	258.0	2D5KY@1|root,32TJC@2|Bacteria,1VD7P@1239|Firmicutes,253JR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01066	457412.RSAG_03283	3.64e-83	250.0	COG0778@1|root,COG0778@2|Bacteria,1V80D@1239|Firmicutes,24I9R@186801|Clostridia,3WRRJ@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	noxC	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
NHEHCBFB_01067	457412.RSAG_03282	2.79e-223	629.0	COG1376@1|root,COG1376@2|Bacteria,1W706@1239|Firmicutes,258MI@186801|Clostridia,3WN4E@541000|Ruminococcaceae	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NHEHCBFB_01068	411459.RUMOBE_03141	4.85e-268	750.0	COG1653@1|root,COG1653@2|Bacteria,1TSF4@1239|Firmicutes,24DIH@186801|Clostridia,3XZJR@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_01069	537007.BLAHAN_05735	1.24e-178	523.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3XZ6N@572511|Blautia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NHEHCBFB_01070	411459.RUMOBE_03138	6.17e-252	704.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSBI@1239|Firmicutes,24E47@186801|Clostridia,3XZZ0@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
NHEHCBFB_01071	411471.SUBVAR_07362	1.24e-145	416.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,3WHYW@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NHEHCBFB_01072	411459.RUMOBE_03135	1.61e-191	533.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,3XZ1D@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NHEHCBFB_01073	411459.RUMOBE_03134	5.72e-283	776.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3XZHY@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	amyE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8,TAT_signal
NHEHCBFB_01074	457412.RSAG_03281	2.85e-207	573.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3WGNI@541000|Ruminococcaceae	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
NHEHCBFB_01076	1121115.AXVN01000099_gene786	0.0	1474.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,3XYPB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	tvaI	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Alpha-amylase_N
NHEHCBFB_01077	1121115.AXVN01000099_gene785	0.0	1141.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XYI4@572511|Blautia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NHEHCBFB_01078	457412.RSAG_04578	3.04e-122	348.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,3WIX7@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
NHEHCBFB_01079	457412.RSAG_03278	0.0	966.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,3WHDC@541000|Ruminococcaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
NHEHCBFB_01080	457412.RSAG_03277	0.0	981.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,3WH68@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
NHEHCBFB_01081	457412.RSAG_03276	2.36e-47	153.0	COG2919@1|root,COG2919@2|Bacteria,1VX29@1239|Firmicutes,252JU@186801|Clostridia,3WMKM@541000|Ruminococcaceae	186801|Clostridia	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
NHEHCBFB_01082	457412.RSAG_03275	2.05e-102	296.0	2EFTM@1|root,3095D@2|Bacteria,1U4G7@1239|Firmicutes,25JHX@186801|Clostridia,3WR8N@541000|Ruminococcaceae	186801|Clostridia	S	Spore cortex protein YabQ (Spore_YabQ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YabQ
NHEHCBFB_01083	457412.RSAG_03274	4.7e-57	177.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia,3WKKJ@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YabP	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
NHEHCBFB_01084	1121115.AXVN01000099_gene779	2.78e-45	146.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,3Y0D7@572511|Blautia	186801|Clostridia	J	COG COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
NHEHCBFB_01085	1121115.AXVN01000099_gene778	1.6e-55	174.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3Y0HQ@572511|Blautia	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
NHEHCBFB_01086	457412.RSAG_03271	3.17e-242	665.0	COG2334@1|root,COG2334@2|Bacteria,1TTBS@1239|Firmicutes,2483F@186801|Clostridia,3WJKX@541000|Ruminococcaceae	186801|Clostridia	S	Spore coat protein, CotS family	cotS	-	-	ko:K06331,ko:K06337	-	-	-	-	ko00000	-	-	-	APH,Choline_kinase
NHEHCBFB_01087	457412.RSAG_03270	9.43e-317	862.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WGBR@541000|Ruminococcaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
NHEHCBFB_01088	1121115.AXVN01000135_gene969	0.0	989.0	COG0441@1|root,COG0441@2|Bacteria,1UHT4@1239|Firmicutes,25E98@186801|Clostridia,3XZ9B@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
NHEHCBFB_01089	457412.RSAG_03268	3.12e-120	342.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,3WRVA@541000|Ruminococcaceae	186801|Clostridia	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
NHEHCBFB_01090	1121115.AXVN01000135_gene972	9.72e-103	296.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3XZXS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
NHEHCBFB_01091	457412.RSAG_03266	9.91e-242	665.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,3WGIY@541000|Ruminococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
NHEHCBFB_01092	1121115.AXVN01000058_gene2556	0.0	1457.0	COG5427@1|root,COG5427@2|Bacteria,1UY7V@1239|Firmicutes,24BA0@186801|Clostridia,3XZJV@572511|Blautia	186801|Clostridia	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
NHEHCBFB_01093	457412.RSAG_04579	0.0	1313.0	COG5427@1|root,COG5427@2|Bacteria,1UXXM@1239|Firmicutes,24EF9@186801|Clostridia,3WHFN@541000|Ruminococcaceae	186801|Clostridia	M	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01094	457412.RSAG_03261	1.05e-156	440.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,3WIGM@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NHEHCBFB_01095	457412.RSAG_03260	0.0	1062.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia,3WIAH@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl hydrolase	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
NHEHCBFB_01096	1121115.AXVN01000058_gene2552	1.72e-40	133.0	2EHIK@1|root,3498W@2|Bacteria,1VYKX@1239|Firmicutes,252YA@186801|Clostridia,3Y0QM@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01097	457412.RSAG_03258	3.26e-173	483.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,24BWV@186801|Clostridia	186801|Clostridia	NOT	Negative regulator of genetic competence	mecB	-	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
NHEHCBFB_01098	1121115.AXVN01000058_gene2550	1.42e-39	131.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia,3Y0MQ@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
NHEHCBFB_01099	457412.RSAG_03256	1.17e-221	612.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,3WIJ5@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	tsgC13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NHEHCBFB_01100	457412.RSAG_03255	9.39e-256	701.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3WHQZ@541000|Ruminococcaceae	186801|Clostridia	S	transport system permease	tsgB13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NHEHCBFB_01101	457412.RSAG_03254	0.0	978.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3WSIS@541000|Ruminococcaceae	186801|Clostridia	S	transport systems ATPase components	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
NHEHCBFB_01102	1121115.AXVN01000058_gene2546	1.21e-286	782.0	COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia,3Y2EG@572511|Blautia	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
NHEHCBFB_01103	1121115.AXVN01000058_gene2545	3.78e-20	81.6	COG1148@1|root,COG1148@2|Bacteria,1UI0M@1239|Firmicutes,25E99@186801|Clostridia,3Y0Q0@572511|Blautia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
NHEHCBFB_01104	457412.RSAG_03250	1.01e-99	290.0	COG0789@1|root,COG0789@2|Bacteria,1V4F1@1239|Firmicutes,24VXI@186801|Clostridia,3WRY4@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NHEHCBFB_01105	1121115.AXVN01000058_gene2543	2.12e-310	847.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3XYP7@572511|Blautia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
NHEHCBFB_01106	1121115.AXVN01000058_gene2542	2.09e-95	278.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,3XZYF@572511|Blautia	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
NHEHCBFB_01107	1121115.AXVN01000058_gene2541	0.0	1301.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,3XYI8@572511|Blautia	186801|Clostridia	T	signaling protein consisting of a modified GGDEF domain and a DHH domain	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
NHEHCBFB_01108	1121115.AXVN01000058_gene2540	3.05e-57	177.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,3Y0A3@572511|Blautia	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
NHEHCBFB_01109	457412.RSAG_03244	5.88e-97	283.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,3WJ32@541000|Ruminococcaceae	186801|Clostridia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
NHEHCBFB_01110	1121115.AXVN01000058_gene2538	1.39e-62	192.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3Y068@572511|Blautia	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
NHEHCBFB_01111	1121115.AXVN01000058_gene2537	1.4e-40	133.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,3Y0KE@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
NHEHCBFB_01112	457412.RSAG_03241	5.47e-177	492.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,3WGSY@541000|Ruminococcaceae	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
NHEHCBFB_01113	1121115.AXVN01000058_gene2535	4.81e-197	546.0	COG4509@1|root,COG4509@2|Bacteria,1V2FT@1239|Firmicutes,24GN2@186801|Clostridia,3XZ9S@572511|Blautia	186801|Clostridia	S	Sortase family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NHEHCBFB_01114	457412.RSAG_03239	0.0	973.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3WHAV@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
NHEHCBFB_01115	1121115.AXVN01000039_gene3304	1.73e-312	849.0	COG3864@1|root,COG3864@2|Bacteria,1VS2U@1239|Firmicutes,24ZZ3@186801|Clostridia,3XZT4@572511|Blautia	186801|Clostridia	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
NHEHCBFB_01116	1121115.AXVN01000039_gene3303	1.1e-78	234.0	2F5U3@1|root,33YD0@2|Bacteria,1VVXV@1239|Firmicutes,250VV@186801|Clostridia,3Y21G@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01117	457412.RSAG_03236	0.0	1116.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGRP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NHEHCBFB_01118	457412.RSAG_03235	1.7e-302	824.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3WHGE@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NHEHCBFB_01119	1121115.AXVN01000039_gene3300	9.57e-304	832.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3XYP4@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	xanP	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
NHEHCBFB_01120	457412.RSAG_03233	0.0	1153.0	COG1404@1|root,COG1404@2|Bacteria,1TQE0@1239|Firmicutes,25B1A@186801|Clostridia,3WI3C@541000|Ruminococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
NHEHCBFB_01121	457412.RSAG_03232	8.77e-193	534.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia,3WSCN@541000|Ruminococcaceae	186801|Clostridia	M	Prolipoprotein diacylglyceryl transferase	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
NHEHCBFB_01122	1121115.AXVN01000039_gene3297	4.93e-208	574.0	COG0010@1|root,COG0010@2|Bacteria,1V6Y2@1239|Firmicutes,24K01@186801|Clostridia,3Y08B@572511|Blautia	186801|Clostridia	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
NHEHCBFB_01123	457412.RSAG_03230	8.55e-188	523.0	COG3247@1|root,COG3247@2|Bacteria,1VAQW@1239|Firmicutes,24QIF@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
NHEHCBFB_01124	457412.RSAG_03229	4.13e-184	512.0	COG2755@1|root,COG2755@2|Bacteria,1VAV9@1239|Firmicutes	1239|Firmicutes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NHEHCBFB_01125	457412.RSAG_03228	4.71e-119	340.0	2DNPY@1|root,32YIB@2|Bacteria,1VHHM@1239|Firmicutes,24NJ3@186801|Clostridia,3WMNS@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4358)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4358
NHEHCBFB_01126	457412.RSAG_03227	0.0	911.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH3T@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
NHEHCBFB_01127	457412.RSAG_03226	1.21e-284	778.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,3WINY@541000|Ruminococcaceae	186801|Clostridia	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
NHEHCBFB_01128	1121115.AXVN01000039_gene3291	5.03e-171	479.0	COG3279@1|root,COG3279@2|Bacteria,1V3QY@1239|Firmicutes,24IT9@186801|Clostridia,3Y1IK@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NHEHCBFB_01129	1121115.AXVN01000039_gene3290	8.12e-48	152.0	2E7JQ@1|root,3321V@2|Bacteria,1VH9B@1239|Firmicutes,24S3M@186801|Clostridia,3Y0WH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01130	1121115.AXVN01000039_gene3289	1.18e-138	391.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia,3Y0B0@572511|Blautia	186801|Clostridia	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
NHEHCBFB_01136	1121115.AXVN01000066_gene3218	2.31e-164	459.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,3XZ8R@572511|Blautia	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
NHEHCBFB_01137	1121115.AXVN01000066_gene3219	1.12e-246	677.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,3XYPY@572511|Blautia	186801|Clostridia	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
NHEHCBFB_01138	1121115.AXVN01000066_gene3220	1.62e-225	620.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia,3XZ6W@572511|Blautia	186801|Clostridia	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
NHEHCBFB_01139	457412.RSAG_01972	6.29e-100	290.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3WKHF@541000|Ruminococcaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
NHEHCBFB_01140	457412.RSAG_01973	2.76e-162	455.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,3WJ9X@541000|Ruminococcaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
NHEHCBFB_01141	1121115.AXVN01000066_gene3223	4.99e-101	292.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3Y003@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
NHEHCBFB_01142	1121115.AXVN01000066_gene3224	9.9e-126	357.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
NHEHCBFB_01143	457412.RSAG_01976	1.45e-152	429.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,3WIHN@541000|Ruminococcaceae	186801|Clostridia	S	YigZ family	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
NHEHCBFB_01144	457412.RSAG_01977	0.0	1568.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia,3WSNS@541000|Ruminococcaceae	186801|Clostridia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
NHEHCBFB_01145	1121115.AXVN01000066_gene3227	1.18e-224	619.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3XYHF@572511|Blautia	186801|Clostridia	GK	Psort location Cytoplasmic, score	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
NHEHCBFB_01146	1121115.AXVN01000066_gene3228	4.97e-220	607.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,3XZ5K@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
NHEHCBFB_01147	457412.RSAG_01980	0.0	1203.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,3WH2A@541000|Ruminococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
NHEHCBFB_01148	1121115.AXVN01000066_gene3230	0.0	1251.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XYZH@572511|Blautia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NHEHCBFB_01149	1121115.AXVN01000066_gene3231	0.0	971.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia,3XYIV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
NHEHCBFB_01150	1121115.AXVN01000066_gene3232	3.68e-179	498.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3XZZF@572511|Blautia	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
NHEHCBFB_01151	1121115.AXVN01000066_gene3233	1.15e-197	547.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,3XZQD@572511|Blautia	186801|Clostridia	S	Carbon-nitrogen hydrolase	nit	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
NHEHCBFB_01152	457412.RSAG_01985	8.3e-253	692.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,3WGSG@541000|Ruminococcaceae	186801|Clostridia	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
NHEHCBFB_01153	1121115.AXVN01000066_gene3236	6.82e-270	738.0	COG2334@1|root,COG2334@2|Bacteria,1UXS1@1239|Firmicutes,25MC4@186801|Clostridia,3XZ7J@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	APH
NHEHCBFB_01154	1121115.AXVN01000066_gene3237	5.05e-232	637.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3XYY9@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
NHEHCBFB_01155	457412.RSAG_01988	1.35e-203	564.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3WN1I@541000|Ruminococcaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NHEHCBFB_01156	1121115.AXVN01000092_gene69	6.09e-228	628.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3XYIT@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NHEHCBFB_01157	1121115.AXVN01000092_gene70	3.23e-310	844.0	COG1653@1|root,COG1653@2|Bacteria,1TPBF@1239|Firmicutes,24920@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_01158	1121115.AXVN01000092_gene71	4.34e-220	607.0	COG2207@1|root,COG2207@2|Bacteria,1UYFM@1239|Firmicutes,247WN@186801|Clostridia,3XZJ7@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NHEHCBFB_01159	1121115.AXVN01000092_gene72	2.37e-312	850.0	COG1653@1|root,COG1653@2|Bacteria,1TPBF@1239|Firmicutes,24920@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_01160	457412.RSAG_01993	8.42e-299	818.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WGB6@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
NHEHCBFB_01161	457412.RSAG_01994	1.06e-156	439.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia,3WS4K@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_01162	1121115.AXVN01000092_gene75	0.0	1096.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3XYUW@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
NHEHCBFB_01163	1121115.AXVN01000092_gene76	5.11e-107	309.0	COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,24FRJ@186801|Clostridia,3XZZN@572511|Blautia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA_2	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
NHEHCBFB_01164	411459.RUMOBE_01996	9.59e-73	225.0	COG1309@1|root,COG1309@2|Bacteria,1V89E@1239|Firmicutes,24JQ7@186801|Clostridia,3Y03H@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NHEHCBFB_01165	411459.RUMOBE_01997	5.83e-141	458.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia,3XYNF@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,DUF3533
NHEHCBFB_01166	1121115.AXVN01000092_gene77	0.0	1785.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,3XYMW@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
NHEHCBFB_01167	1121115.AXVN01000092_gene78	1.03e-174	493.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,3Y281@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01168	457412.RSAG_01999	5.64e-75	224.0	COG5561@1|root,COG5561@2|Bacteria,1VBDY@1239|Firmicutes,259Y8@186801|Clostridia,3WQWE@541000|Ruminococcaceae	186801|Clostridia	S	CGGC	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
NHEHCBFB_01169	457412.RSAG_02000	1.75e-174	487.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,3WHNG@541000|Ruminococcaceae	186801|Clostridia	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
NHEHCBFB_01170	1121115.AXVN01000074_gene2302	8.48e-244	671.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,3XZQC@572511|Blautia	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NHEHCBFB_01171	457412.RSAG_02002	3.37e-239	660.0	COG0614@1|root,COG0614@2|Bacteria,1TSAF@1239|Firmicutes,24ATS@186801|Clostridia,3WI3J@541000|Ruminococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
NHEHCBFB_01172	1121115.AXVN01000074_gene2300	1.75e-143	405.0	2DG4Z@1|root,2ZUIM@2|Bacteria,1V47V@1239|Firmicutes,24HN9@186801|Clostridia,3Y0J3@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
NHEHCBFB_01173	457412.RSAG_02004	8.75e-199	551.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3WGWZ@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_01174	457412.RSAG_02005	1.36e-79	236.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,3WJYT@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NHEHCBFB_01175	1121115.AXVN01000074_gene2291	2.02e-212	586.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,3Y02V@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
NHEHCBFB_01176	1121115.AXVN01000074_gene2290	2.3e-188	523.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,3XYTK@572511|Blautia	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
NHEHCBFB_01177	457412.RSAG_02014	1.44e-142	403.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,3WIVU@541000|Ruminococcaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
NHEHCBFB_01178	1256908.HMPREF0373_02578	1.35e-223	622.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia,25VAH@186806|Eubacteriaceae	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17,Fer4_9
NHEHCBFB_01179	1121115.AXVN01000074_gene2287	0.0	880.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3XYZK@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NHEHCBFB_01180	1408437.JNJN01000053_gene2081	1.01e-27	102.0	COG1595@1|root,COG1595@2|Bacteria,1V1AX@1239|Firmicutes,24EM3@186801|Clostridia,25XG2@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
NHEHCBFB_01181	658659.HMPREF0983_01727	1.31e-45	149.0	COG1595@1|root,COG1595@2|Bacteria,1V1EX@1239|Firmicutes	1239|Firmicutes	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
NHEHCBFB_01182	457412.RSAG_00860	7.41e-131	371.0	COG3760@1|root,COG3760@2|Bacteria,1V1JF@1239|Firmicutes,24FVD@186801|Clostridia,3WIZ6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
NHEHCBFB_01183	457412.RSAG_00003	2.62e-55	174.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia,3WKRS@541000|Ruminococcaceae	186801|Clostridia	S	Small, acid-soluble spore protein, alpha beta type	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
NHEHCBFB_01184	1121115.AXVN01000002_gene1367	1.27e-90	265.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3Y038@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
NHEHCBFB_01185	1121115.AXVN01000002_gene1368	4.62e-125	356.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3XZUU@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
NHEHCBFB_01186	1121115.AXVN01000002_gene1369	2.76e-110	317.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,3XZXZ@572511|Blautia	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
NHEHCBFB_01187	1121115.AXVN01000002_gene1370	2.51e-94	281.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia,3XZBA@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01188	1121115.AXVN01000002_gene1371	6.8e-221	609.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia,3Y01Q@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
NHEHCBFB_01189	1121115.AXVN01000002_gene1372	0.0	951.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia,3XZA8@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NHEHCBFB_01190	1121115.AXVN01000002_gene1373	2.49e-188	523.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,3XZGG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yjbM	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NHEHCBFB_01191	1121115.AXVN01000002_gene1374	0.0	1288.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,3XYGY@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
NHEHCBFB_01192	457412.RSAG_00012	5.24e-150	422.0	2E2IE@1|root,32XN3@2|Bacteria,1VD21@1239|Firmicutes,24KKS@186801|Clostridia,3WM0H@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01193	1121115.AXVN01000002_gene1376	1.08e-245	674.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,3XYMC@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NHEHCBFB_01194	1121115.AXVN01000002_gene1377	6.57e-107	310.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3XZX6@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
NHEHCBFB_01195	457412.RSAG_00015	1.76e-126	359.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia,3WIFA@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
NHEHCBFB_01196	1121115.AXVN01000002_gene1379	1.46e-261	717.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia,3XYWI@572511|Blautia	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
NHEHCBFB_01197	1121115.AXVN01000002_gene1380	1.76e-147	416.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia,3XZ1U@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
NHEHCBFB_01198	1121115.AXVN01000002_gene1381	3.2e-301	823.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,3XZ14@572511|Blautia	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
NHEHCBFB_01199	1121115.AXVN01000002_gene1382	5.35e-139	392.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,3XYJ4@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
NHEHCBFB_01200	1121115.AXVN01000002_gene1383	2.6e-81	240.0	COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,3XZDT@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
NHEHCBFB_01201	457412.RSAG_00021	6.15e-278	766.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
NHEHCBFB_01202	457412.RSAG_00022	1.52e-196	550.0	COG0614@1|root,COG5386@1|root,COG0614@2|Bacteria,COG5386@2|Bacteria,1UYC0@1239|Firmicutes,24D7G@186801|Clostridia,3WSRF@541000|Ruminococcaceae	186801|Clostridia	M	Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01203	457412.RSAG_00023	2.96e-285	779.0	COG0614@1|root,COG0614@2|Bacteria,1TQ4U@1239|Firmicutes,249I2@186801|Clostridia,3WHGS@541000|Ruminococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
NHEHCBFB_01204	1121115.AXVN01000002_gene1388	1.42e-224	621.0	COG0609@1|root,COG0609@2|Bacteria,1TQXW@1239|Firmicutes,249TJ@186801|Clostridia,3Y151@572511|Blautia	186801|Clostridia	P	FecCD transport family	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NHEHCBFB_01205	457412.RSAG_00025	1.49e-272	746.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,3WHJY@541000|Ruminococcaceae	186801|Clostridia	HP	ATPases associated with a variety of cellular activities	fepC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran,zf-like
NHEHCBFB_01206	1121115.AXVN01000002_gene1390	3.21e-178	496.0	COG0463@1|root,COG0463@2|Bacteria,1TRRK@1239|Firmicutes,24CHM@186801|Clostridia,3Y03K@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NHEHCBFB_01207	1121115.AXVN01000002_gene1391	2.51e-56	175.0	2F99N@1|root,340RC@2|Bacteria,1VX34@1239|Firmicutes,257JQ@186801|Clostridia,3Y26Y@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01208	457412.RSAG_00028	0.0	1024.0	COG4733@1|root,COG5279@1|root,COG4733@2|Bacteria,COG5279@2|Bacteria,1V1JE@1239|Firmicutes,24GTB@186801|Clostridia,3WK9S@541000|Ruminococcaceae	186801|Clostridia	D	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01209	1121115.AXVN01000002_gene1393	0.0	1202.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3XZNF@572511|Blautia	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
NHEHCBFB_01210	1121115.AXVN01000002_gene1394	1.65e-270	738.0	COG0463@1|root,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,249HH@186801|Clostridia,3XZ06@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	sunS	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
NHEHCBFB_01211	457412.RSAG_00031	8.59e-27	105.0	COG2931@1|root,COG2931@2|Bacteria,1TSGB@1239|Firmicutes,247TS@186801|Clostridia	186801|Clostridia	Q	PFAM Collagen triple helix	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
NHEHCBFB_01212	1121115.AXVN01000002_gene1396	0.0	1062.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NHEHCBFB_01213	457412.RSAG_00033	4.17e-194	538.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,3WHDE@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
NHEHCBFB_01214	1121115.AXVN01000002_gene1398	5.05e-314	856.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,3Y170@572511|Blautia	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
NHEHCBFB_01215	1121115.AXVN01000002_gene1399	2.86e-217	600.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,3XZ3D@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
NHEHCBFB_01216	457412.RSAG_00036	5.29e-196	542.0	COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24C8P@186801|Clostridia,3WHKS@541000|Ruminococcaceae	186801|Clostridia	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
NHEHCBFB_01217	1121115.AXVN01000002_gene1401	1.89e-91	267.0	COG1150@1|root,COG1150@2|Bacteria,1V27J@1239|Firmicutes,24FU5@186801|Clostridia,3Y1I7@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8
NHEHCBFB_01218	1121115.AXVN01000002_gene1402	0.0	1291.0	COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,3Y0ZT@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,Fer4_7,Pyr_redox_2
NHEHCBFB_01219	1121115.AXVN01000002_gene1403	5.15e-109	313.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,3Y10T@572511|Blautia	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
NHEHCBFB_01220	1121115.AXVN01000002_gene1404	9.19e-243	665.0	COG1035@1|root,COG4656@1|root,COG1035@2|Bacteria,COG4656@2|Bacteria,1TPBM@1239|Firmicutes,24CJH@186801|Clostridia,3Y13N@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,FrhB_FdhB_C
NHEHCBFB_01221	1121115.AXVN01000002_gene1405	1.84e-263	719.0	COG0479@1|root,COG0479@2|Bacteria,1TP8R@1239|Firmicutes,247QI@186801|Clostridia,3Y1ET@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
NHEHCBFB_01222	1121115.AXVN01000002_gene1406	1.87e-215	593.0	COG0543@1|root,COG0543@2|Bacteria,1TQBZ@1239|Firmicutes,248GQ@186801|Clostridia,3Y1HE@572511|Blautia	186801|Clostridia	CH	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
NHEHCBFB_01223	1121115.AXVN01000002_gene1407	3.15e-163	456.0	COG4656@1|root,COG4656@2|Bacteria,1UY26@1239|Firmicutes,24D3I@186801|Clostridia,3Y0XC@572511|Blautia	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_7,Fer4_9
NHEHCBFB_01224	1121115.AXVN01000002_gene1408	0.0	1070.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3Y1CZ@572511|Blautia	186801|Clostridia	C	Glucose inhibited division protein A	-	-	1.3.5.1,1.3.5.4,1.3.99.33	ko:K00239,ko:K00244,ko:K17363	ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164,R10330	RC00045,RC00669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,FMN_red
NHEHCBFB_01225	1121115.AXVN01000002_gene1409	8.18e-208	573.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3XZ8S@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
NHEHCBFB_01226	1121115.AXVN01000002_gene1410	7.64e-131	371.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,3XZI9@572511|Blautia	186801|Clostridia	C	COG COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
NHEHCBFB_01227	457412.RSAG_00046	1.76e-165	462.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia,3WIT8@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
NHEHCBFB_01228	1121115.AXVN01000002_gene1412	4.82e-113	324.0	COG1905@1|root,COG1905@2|Bacteria,1V4IR@1239|Firmicutes,25CD0@186801|Clostridia,3XZET@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
NHEHCBFB_01229	457412.RSAG_00048	0.0	1226.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3WGG2@541000|Ruminococcaceae	186801|Clostridia	C	NADH ubiquinone oxidoreductase	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
NHEHCBFB_01230	457412.RSAG_00049	0.0	1147.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,3WGMQ@541000|Ruminococcaceae	186801|Clostridia	C	hydrogenase large subunit	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,NADH-G_4Fe-4S_3
NHEHCBFB_01232	457412.RSAG_01899	2.67e-43	140.0	COG2155@1|root,COG2155@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF378)	yuzA	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
NHEHCBFB_01233	457412.RSAG_01898	9.21e-228	630.0	2E2H9@1|root,32XM9@2|Bacteria,1VC5F@1239|Firmicutes,24PWJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4878,DUF5067
NHEHCBFB_01234	457412.RSAG_01897	2.59e-229	630.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3WHZJ@541000|Ruminococcaceae	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
NHEHCBFB_01235	1121115.AXVN01000156_gene546	1.26e-95	280.0	2979U@1|root,2ZUHG@2|Bacteria,1W35F@1239|Firmicutes,256C8@186801|Clostridia,3Y0TR@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01236	1121115.AXVN01000156_gene545	2.08e-112	323.0	COG5652@1|root,COG5652@2|Bacteria,1V72A@1239|Firmicutes,259NP@186801|Clostridia,3Y02J@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NHEHCBFB_01237	1121115.AXVN01000156_gene544	1.93e-175	491.0	COG4822@1|root,COG4822@2|Bacteria	2|Bacteria	H	anaerobic cobalamin biosynthetic process	cbiK	-	4.99.1.3	ko:K02006,ko:K02190	ko00860,ko01100,ko02010,map00860,map01100,map02010	M00245,M00246	R05807	RC01012	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran,CbiK,TP_methylase
NHEHCBFB_01238	457412.RSAG_01892	0.0	1051.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TR4U@1239|Firmicutes,24JVF@186801|Clostridia,3WJ1J@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
NHEHCBFB_01239	457412.RSAG_01891	0.0	1195.0	COG2972@1|root,COG2972@2|Bacteria,1TSE1@1239|Firmicutes,24B0H@186801|Clostridia	186801|Clostridia	T	HAMP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NHEHCBFB_01240	457412.RSAG_01890	4.53e-303	825.0	COG1653@1|root,COG1653@2|Bacteria,1TQJU@1239|Firmicutes,24AHT@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NHEHCBFB_01241	457412.RSAG_01889	8.47e-207	572.0	COG1175@1|root,COG1175@2|Bacteria,1UXJV@1239|Firmicutes,25MIZ@186801|Clostridia,3WQ0J@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NHEHCBFB_01242	457412.RSAG_01888	1.14e-196	546.0	COG0395@1|root,COG0395@2|Bacteria,1TSJ9@1239|Firmicutes,24ERB@186801|Clostridia	186801|Clostridia	P	abc transporter permease protein	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NHEHCBFB_01243	457412.RSAG_01887	9.51e-295	801.0	COG4030@1|root,COG4030@2|Bacteria,1TRZY@1239|Firmicutes,249GP@186801|Clostridia,3WHHT@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
NHEHCBFB_01244	457412.RSAG_01886	4.24e-310	843.0	COG1653@1|root,COG1653@2|Bacteria,1TQJU@1239|Firmicutes,24AHT@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_01245	457412.RSAG_01885	3.03e-228	628.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1UVPR@1239|Firmicutes,25KKF@186801|Clostridia,3WPZY@541000|Ruminococcaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NHEHCBFB_01246	457412.RSAG_01884	0.0	1172.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WGKA@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
NHEHCBFB_01247	457412.RSAG_01883	2.99e-248	682.0	COG1609@1|root,COG1609@2|Bacteria,1TS5M@1239|Firmicutes,24AWP@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NHEHCBFB_01248	457412.RSAG_01882	0.0	1159.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WGKA@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase catalytic	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
NHEHCBFB_01249	457412.RSAG_01875	5.1e-235	646.0	COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,25CN5@186801|Clostridia	186801|Clostridia	I	Diacylglycerol kinase catalytic domain	ytlR	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
NHEHCBFB_01250	457412.RSAG_01874	8.89e-213	586.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,249QG@186801|Clostridia,3WHH9@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
NHEHCBFB_01251	457412.RSAG_01873	1.95e-114	328.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,24FTH@186801|Clostridia,3WJ8H@541000|Ruminococcaceae	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
NHEHCBFB_01252	1121115.AXVN01000047_gene1250	6.59e-256	700.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,3XZFI@572511|Blautia	186801|Clostridia	EH	Psort location Cytoplasmic, score 8.87	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
NHEHCBFB_01253	1121115.AXVN01000047_gene1251	4.74e-264	729.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,3XZ35@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
NHEHCBFB_01254	457412.RSAG_01870	1.05e-253	698.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the TelA family	-	-	-	-	-	-	-	-	-	-	-	-	TelA
NHEHCBFB_01255	1121115.AXVN01000047_gene1253	6.51e-247	678.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3XYGT@572511|Blautia	186801|Clostridia	H	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
NHEHCBFB_01256	457412.RSAG_01868	0.0	2948.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,3WGJN@541000|Ruminococcaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
NHEHCBFB_01257	1121115.AXVN01000047_gene1255	0.0	1308.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,3XZC9@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
NHEHCBFB_01258	1121115.AXVN01000047_gene1256	0.0	964.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3XYNA@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purF_1	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
NHEHCBFB_01259	1121115.AXVN01000047_gene1257	6.29e-97	286.0	COG1033@1|root,COG1033@2|Bacteria,1VTBG@1239|Firmicutes,24YPV@186801|Clostridia,3Y1R8@572511|Blautia	186801|Clostridia	S	growth of symbiont in host cell	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01260	1121115.AXVN01000047_gene1258	1.52e-43	141.0	COG1396@1|root,COG1396@2|Bacteria,1UHV9@1239|Firmicutes,25E41@186801|Clostridia,3Y0RB@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NHEHCBFB_01261	457412.RSAG_01862	0.0	1006.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,3WH36@541000|Ruminococcaceae	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
NHEHCBFB_01262	1121115.AXVN01000047_gene1260	2.46e-217	600.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,3XYUB@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
NHEHCBFB_01263	457412.RSAG_01860	0.0	1331.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,3WGDZ@541000|Ruminococcaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
NHEHCBFB_01264	1121115.AXVN01000047_gene1262	1.67e-177	495.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,2480R@186801|Clostridia,3XYZ9@572511|Blautia	186801|Clostridia	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	-	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
NHEHCBFB_01265	1121115.AXVN01000047_gene1263	7.18e-57	177.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3Y05R@572511|Blautia	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
NHEHCBFB_01266	1121115.AXVN01000047_gene1264	0.0	984.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
NHEHCBFB_01267	1121115.AXVN01000047_gene1265	5.98e-111	319.0	2E823@1|root,332G5@2|Bacteria,1V8A8@1239|Firmicutes,24NHT@186801|Clostridia,3Y088@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01268	1121115.AXVN01000047_gene1266	0.0	932.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3XZR0@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
NHEHCBFB_01269	457412.RSAG_01854	2.47e-187	521.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia,3WIZ0@541000|Ruminococcaceae	186801|Clostridia	M	Ami_2	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
NHEHCBFB_01270	1121115.AXVN01000047_gene1268	6.91e-174	484.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3XZ1G@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
NHEHCBFB_01271	1121115.AXVN01000047_gene1269	1.13e-292	798.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3XYNE@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
NHEHCBFB_01273	1121115.AXVN01000047_gene1270	6.35e-48	153.0	2EVPB@1|root,33P3A@2|Bacteria,1VN4M@1239|Firmicutes,24TZY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01274	1256908.HMPREF0373_02163	1.98e-21	87.0	2EPX6@1|root,328RW@2|Bacteria,1UUQ7@1239|Firmicutes,257FE@186801|Clostridia	1256908.HMPREF0373_02163|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01275	1235800.C819_00258	0.0	899.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,27I9M@186928|unclassified Lachnospiraceae	186801|Clostridia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NHEHCBFB_01276	457412.RSAG_02029	5.83e-152	428.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WH0X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_01277	457412.RSAG_02030	2.15e-238	656.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia,3WJ5X@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NHEHCBFB_01278	1121115.AXVN01000152_gene3982	3.68e-160	449.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,3XZF5@572511|Blautia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_01279	457412.RSAG_02032	2.17e-39	130.0	COG2909@1|root,COG2909@2|Bacteria,1VGAF@1239|Firmicutes,24SMP@186801|Clostridia,3WM0N@541000|Ruminococcaceae	186801|Clostridia	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NHEHCBFB_01280	742765.HMPREF9457_01065	1.75e-75	226.0	COG1476@1|root,COG1476@2|Bacteria,1V4DH@1239|Firmicutes,24HSN@186801|Clostridia,27WQG@189330|Dorea	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_01281	1121115.AXVN01000094_gene768	1.3e-94	276.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
NHEHCBFB_01282	457412.RSAG_02035	3.13e-86	254.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
NHEHCBFB_01283	1121115.AXVN01000094_gene766	1.05e-101	294.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3XZVZ@572511|Blautia	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
NHEHCBFB_01284	1121115.AXVN01000094_gene765	1.57e-179	499.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,3XYU9@572511|Blautia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
NHEHCBFB_01285	1121115.AXVN01000094_gene764	4.1e-181	505.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,3XYPD@572511|Blautia	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
NHEHCBFB_01286	1121115.AXVN01000094_gene763	1.09e-249	686.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3XZ7W@572511|Blautia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NHEHCBFB_01287	1121115.AXVN01000094_gene762	8.15e-204	563.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3XZE9@572511|Blautia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NHEHCBFB_01288	457412.RSAG_02041	2.08e-139	394.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,3WH1B@541000|Ruminococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
NHEHCBFB_01289	1121115.AXVN01000094_gene760	0.0	1464.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3XYJU@572511|Blautia	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
NHEHCBFB_01290	457412.RSAG_02043	9.38e-312	850.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WGYG@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
NHEHCBFB_01291	1121115.AXVN01000094_gene758	5.7e-133	378.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,3XYT9@572511|Blautia	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NHEHCBFB_01292	1121115.AXVN01000094_gene757	1.26e-288	790.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3XYJC@572511|Blautia	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
NHEHCBFB_01293	1121115.AXVN01000094_gene756	6.7e-115	331.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,3Y01K@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
NHEHCBFB_01294	457412.RSAG_02047	0.0	918.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,2492H@186801|Clostridia,3WGV9@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase family M20/M25/M40	abgB	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NHEHCBFB_01295	457412.RSAG_02048	0.0	1090.0	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia,3WGCG@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE,dCache_1
NHEHCBFB_01296	457412.RSAG_02049	0.0	1841.0	COG0477@1|root,COG2814@2|Bacteria,1V3QU@1239|Firmicutes,25BMP@186801|Clostridia	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NHEHCBFB_01297	457412.RSAG_02050	1.41e-239	657.0	COG4866@1|root,COG4866@2|Bacteria,1VTHP@1239|Firmicutes,24XR0@186801|Clostridia	186801|Clostridia	S	Uncharacterised conserved protein (DUF2156)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2156
NHEHCBFB_01298	457412.RSAG_02051	1.35e-106	307.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia,3WJHM@541000|Ruminococcaceae	186801|Clostridia	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
NHEHCBFB_01299	1121115.AXVN01000189_gene1038	2.29e-181	505.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,3XZDC@572511|Blautia	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
NHEHCBFB_01300	457412.RSAG_02053	9.97e-103	297.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3WJM2@541000|Ruminococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
NHEHCBFB_01301	1121115.AXVN01000180_gene2884	1.1e-315	861.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3Y1CE@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_01302	1121115.AXVN01000180_gene2885	6.34e-227	624.0	COG2207@1|root,COG2207@2|Bacteria,1VT0T@1239|Firmicutes,24YTA@186801|Clostridia,3Y0YN@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NHEHCBFB_01303	457412.RSAG_02056	9.86e-146	410.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,3WJ59@541000|Ruminococcaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
NHEHCBFB_01304	1121115.AXVN01000133_gene744	1.59e-297	815.0	2CGG8@1|root,30FQ1@2|Bacteria,1UEDU@1239|Firmicutes,25JA2@186801|Clostridia,3Y0ZN@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01305	1121115.AXVN01000133_gene743	1.39e-294	805.0	COG0642@1|root,COG2205@2|Bacteria,1TRD2@1239|Firmicutes,247M3@186801|Clostridia,3Y0A6@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NHEHCBFB_01306	1121115.AXVN01000133_gene742	1.56e-152	429.0	COG0745@1|root,COG0745@2|Bacteria,1TT73@1239|Firmicutes,2487E@186801|Clostridia,3Y0AH@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_01308	1121115.AXVN01000133_gene741	2.2e-274	750.0	29WCT@1|root,30HYG@2|Bacteria,1TYPB@1239|Firmicutes,258RC@186801|Clostridia,3Y1W1@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NHEHCBFB_01309	457412.RSAG_02063	7.64e-131	371.0	COG1595@1|root,COG1595@2|Bacteria,1V1JW@1239|Firmicutes,24FYN@186801|Clostridia,3WJKF@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4_2
NHEHCBFB_01310	457412.RSAG_02064	6.89e-193	535.0	COG5464@1|root,COG5464@2|Bacteria,1V2ZE@1239|Firmicutes,25DF2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
NHEHCBFB_01311	457412.RSAG_00431	6.45e-236	661.0	2E6HB@1|root,3314J@2|Bacteria,1VGBM@1239|Firmicutes,24T1M@186801|Clostridia,3WMCU@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01312	457412.RSAG_00432	7.24e-80	240.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WRUB@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NHEHCBFB_01313	1121115.AXVN01000079_gene2733	0.0	956.0	COG0772@1|root,COG0772@2|Bacteria,1TRIP@1239|Firmicutes,258QF@186801|Clostridia,3Y1Z2@572511|Blautia	186801|Clostridia	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01314	457412.RSAG_02066	3.83e-68	206.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,3WJM5@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
NHEHCBFB_01315	1121115.AXVN01000079_gene2735	2.48e-223	614.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes,24CTG@186801|Clostridia,3Y1A4@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01316	1121115.AXVN01000079_gene2736	1.57e-37	126.0	2C4UK@1|root,346TK@2|Bacteria,1W0FK@1239|Firmicutes,2530T@186801|Clostridia,3Y21U@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01317	457412.RSAG_02083	1.01e-35	120.0	2E7J1@1|root,33DKE@2|Bacteria,1VM3N@1239|Firmicutes,24VIG@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01318	457412.RSAG_02086	8.62e-126	358.0	COG0400@1|root,COG0400@2|Bacteria,1VBK0@1239|Firmicutes,24N89@186801|Clostridia,3WJI9@541000|Ruminococcaceae	186801|Clostridia	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01319	457412.RSAG_02087	0.0	903.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,3WHQP@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
NHEHCBFB_01320	457412.RSAG_02088	8.45e-160	447.0	COG1028@1|root,COG1028@2|Bacteria,1V0T9@1239|Firmicutes,24ASP@186801|Clostridia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
NHEHCBFB_01321	1121115.AXVN01000079_gene2743	5.17e-123	351.0	COG3275@1|root,COG3275@2|Bacteria,1UZUT@1239|Firmicutes,25BAU@186801|Clostridia,3Y2E5@572511|Blautia	186801|Clostridia	T	phosphorelay sensor kinase activity	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	ECF_trnsprt
NHEHCBFB_01322	1121115.AXVN01000079_gene2744	1.3e-240	660.0	COG1957@1|root,COG1957@2|Bacteria,1TRQQ@1239|Firmicutes,25C8Y@186801|Clostridia,3Y2EI@572511|Blautia	186801|Clostridia	F	Inosine-uridine preferring nucleoside hydrolase	iunH	-	3.2.2.1	ko:K01239,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
NHEHCBFB_01323	1121115.AXVN01000003_gene1623	9.66e-219	602.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,3XZM3@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
NHEHCBFB_01324	1121115.AXVN01000003_gene1622	0.0	900.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3XZ00@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
NHEHCBFB_01325	457412.RSAG_00638	5.78e-225	622.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3WGWV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
NHEHCBFB_01326	457412.RSAG_00637	0.0	1566.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,3WHBB@541000|Ruminococcaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
NHEHCBFB_01327	1121115.AXVN01000003_gene1618	2.26e-149	419.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24J27@186801|Clostridia,3Y2AD@572511|Blautia	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NHEHCBFB_01328	1121115.AXVN01000003_gene1617	0.0	1017.0	COG0497@1|root,COG0497@2|Bacteria,1UJV8@1239|Firmicutes,25FAU@186801|Clostridia	186801|Clostridia	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
NHEHCBFB_01329	1121115.AXVN01000003_gene1616	1.32e-187	525.0	COG2885@1|root,COG2885@2|Bacteria,1V6HB@1239|Firmicutes,24ARV@186801|Clostridia,3Y17K@572511|Blautia	186801|Clostridia	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
NHEHCBFB_01330	1121115.AXVN01000003_gene1615	5.65e-220	606.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3XZRD@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
NHEHCBFB_01331	1121115.AXVN01000003_gene1614	1.64e-74	223.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,3Y019@572511|Blautia	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
NHEHCBFB_01332	1121115.AXVN01000003_gene1613	1.71e-138	392.0	COG0681@1|root,COG0681@2|Bacteria,1V2SF@1239|Firmicutes,24AWM@186801|Clostridia,3XZTM@572511|Blautia	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
NHEHCBFB_01333	1121115.AXVN01000003_gene1612	1.46e-202	560.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,3XYWP@572511|Blautia	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
NHEHCBFB_01334	1121115.AXVN01000003_gene1611	9.68e-172	480.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,3XZF8@572511|Blautia	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
NHEHCBFB_01335	457412.RSAG_00628	1.6e-86	254.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,3WMJ4@541000|Ruminococcaceae	186801|Clostridia	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
NHEHCBFB_01336	1121115.AXVN01000003_gene1609	1.31e-210	581.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,3XYQB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
NHEHCBFB_01337	457412.RSAG_00626	1.07e-283	775.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3WGVK@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ribose-phosphate pyrophosphokinase family	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
NHEHCBFB_01338	1121115.AXVN01000003_gene1607	0.0	917.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,3XYRJ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
NHEHCBFB_01339	457412.RSAG_00624	2.91e-312	851.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,3WGNU@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
NHEHCBFB_01340	1121115.AXVN01000003_gene1605	8.27e-144	406.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3XZ7V@572511|Blautia	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
NHEHCBFB_01341	1121115.AXVN01000003_gene1604	2.61e-239	658.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,3XYNR@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
NHEHCBFB_01342	1121115.AXVN01000003_gene1603	1.45e-202	561.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,3XYQK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yvgN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NHEHCBFB_01343	457412.RSAG_00620	2.97e-71	216.0	2CEVS@1|root,30HAB@2|Bacteria,1UHCU@1239|Firmicutes,25Q3B@186801|Clostridia,3WR1K@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01344	1121115.AXVN01000003_gene1601	1.02e-34	118.0	2FK7C@1|root,34BV3@2|Bacteria,1W6KA@1239|Firmicutes,254TZ@186801|Clostridia,3Y0MF@572511|Blautia	186801|Clostridia	S	Predicted RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RNA_bind_2
NHEHCBFB_01345	1121115.AXVN01000003_gene1600	1.83e-183	510.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,3XYPW@572511|Blautia	186801|Clostridia	D	cell division inhibitor, membrane ATPase MinD	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	AAA_31,CbiA
NHEHCBFB_01346	1121115.AXVN01000003_gene1599	0.0	1261.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,3XZEI@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	cooS1	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
NHEHCBFB_01347	1121115.AXVN01000003_gene1598	6.85e-178	496.0	COG3640@1|root,COG3640@2|Bacteria,1TPCY@1239|Firmicutes,247JM@186801|Clostridia,3XZK1@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
NHEHCBFB_01348	457412.RSAG_00615	0.0	1398.0	COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase complex beta subunit	cdhC	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
NHEHCBFB_01349	1121115.AXVN01000003_gene1595	1.85e-212	588.0	COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3XZ3W@572511|Blautia	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsD	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
NHEHCBFB_01350	457412.RSAG_00613	0.0	880.0	COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3WNR9@541000|Ruminococcaceae	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsC	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
NHEHCBFB_01351	457412.RSAG_00612	2.8e-185	515.0	COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3WNXA@541000|Ruminococcaceae	186801|Clostridia	E	Pterin binding enzyme	acsE	-	2.1.1.258	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R02289,R10243	RC00004,RC00113,RC01144,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
NHEHCBFB_01352	1121115.AXVN01000003_gene1592	0.0	1262.0	COG1018@1|root,COG3894@1|root,COG1018@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,3XYV5@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
NHEHCBFB_01353	1121115.AXVN01000003_gene1591	2.12e-157	441.0	2C5Z2@1|root,32A20@2|Bacteria,1V5CS@1239|Firmicutes,24M7C@186801|Clostridia,3XZ4M@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
NHEHCBFB_01354	457412.RSAG_00609	3.83e-139	394.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,3WJ4I@541000|Ruminococcaceae	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
NHEHCBFB_01355	1121115.AXVN01000003_gene1589	6.66e-200	554.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3XZ53@572511|Blautia	186801|Clostridia	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
NHEHCBFB_01356	1121115.AXVN01000003_gene1588	2.19e-188	525.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.4.21.96	ko:K01361,ko:K13277,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Amidase_2,Big_2,CBM_X2,DUF1983,DUF2961,Glucosaminidase,LRR_5,Laminin_G_3,PA,Peptidase_S8,Phage-tail_3,SLH,fn3_5
NHEHCBFB_01357	457412.RSAG_00606	8.58e-223	615.0	COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia,3WHWJ@541000|Ruminococcaceae	186801|Clostridia	P	Menaquinone biosynthesis	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,Phosphonate-bd,VitK2_biosynth
NHEHCBFB_01358	1121115.AXVN01000003_gene1586	7.28e-173	484.0	COG0600@1|root,COG0600@2|Bacteria,1V73W@1239|Firmicutes,24A2R@186801|Clostridia,3Y1BD@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran,BPD_transp_1
NHEHCBFB_01359	1121115.AXVN01000003_gene1585	4.06e-134	380.0	COG1116@1|root,COG1116@2|Bacteria,1VAD8@1239|Firmicutes,24GFE@186801|Clostridia,3Y1PX@572511|Blautia	186801|Clostridia	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NHEHCBFB_01360	457412.RSAG_00603	2.74e-242	665.0	COG0317@1|root,COG0317@2|Bacteria,1TQW3@1239|Firmicutes,2483C@186801|Clostridia,3WH98@541000|Ruminococcaceae	186801|Clostridia	KT	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
NHEHCBFB_01361	457412.RSAG_00602	0.0	967.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,248UK@186801|Clostridia,3WJ03@541000|Ruminococcaceae	186801|Clostridia	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
NHEHCBFB_01362	457412.RSAG_00601	5.26e-281	767.0	COG1820@1|root,COG1820@2|Bacteria,1UK3V@1239|Firmicutes,25FIQ@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation	iadA	-	-	ko:K01305	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Amidohydro_1,Amidohydro_3
NHEHCBFB_01363	457412.RSAG_00600	3.43e-234	643.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,249GM@186801|Clostridia,3WGAM@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
NHEHCBFB_01364	457412.RSAG_00599	0.0	1174.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia,3WIA6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
NHEHCBFB_01365	1121115.AXVN01000003_gene1579	1.07e-68	207.0	COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,24NYY@186801|Clostridia,3Y09V@572511|Blautia	186801|Clostridia	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
NHEHCBFB_01367	457412.RSAG_02489	2.45e-64	209.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_01368	457412.RSAG_02489	5.95e-25	102.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_01369	457412.RSAG_02487	1.95e-41	136.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,3WKZF@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NHEHCBFB_01370	457412.RSAG_02486	2.15e-99	289.0	2DZF8@1|root,33ZUF@2|Bacteria,1VYFM@1239|Firmicutes,25E2Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01371	457412.RSAG_02485	7.57e-207	571.0	COG2267@1|root,COG2267@2|Bacteria,1TR25@1239|Firmicutes,24APA@186801|Clostridia,3WKUN@541000|Ruminococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
NHEHCBFB_01372	457412.RSAG_02483	1.14e-48	155.0	2DN0F@1|root,32UQJ@2|Bacteria,1VBR6@1239|Firmicutes,24NWZ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
NHEHCBFB_01373	457412.RSAG_02481	8.17e-52	163.0	2EC32@1|root,33621@2|Bacteria,1VIVU@1239|Firmicutes,24Q0K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
NHEHCBFB_01374	457412.RSAG_00820	1.07e-26	103.0	COG4734@1|root,COG4734@2|Bacteria,1UZZ6@1239|Firmicutes,24DE1@186801|Clostridia	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NHEHCBFB_01375	457412.RSAG_02479	0.0	1645.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WH14@541000|Ruminococcaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
NHEHCBFB_01376	1121115.AXVN01000101_gene821	1.44e-35	120.0	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia,3Y0SX@572511|Blautia	186801|Clostridia	S	COG NOG17973 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
NHEHCBFB_01377	457412.RSAG_02477	0.0	933.0	COG1055@1|root,COG1055@2|Bacteria,1TT1V@1239|Firmicutes,24ART@186801|Clostridia	186801|Clostridia	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
NHEHCBFB_01378	457412.RSAG_02476	5.95e-239	657.0	COG1102@1|root,COG1102@2|Bacteria,1TSIF@1239|Firmicutes,24BT4@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NHEHCBFB_01379	457412.RSAG_02475	3.85e-314	856.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WHBC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NHEHCBFB_01380	1121115.AXVN01000101_gene817	7.45e-208	575.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,249AX@186801|Clostridia,3Y0AZ@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_01381	457412.RSAG_02473	2.69e-101	294.0	COG1846@1|root,COG1846@2|Bacteria,1VFS1@1239|Firmicutes,24QXV@186801|Clostridia,3WRVD@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NHEHCBFB_01382	1121115.AXVN01000101_gene815	0.0	1325.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XYTY@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NHEHCBFB_01383	1121115.AXVN01000101_gene814	0.0	1169.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XZ2D@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NHEHCBFB_01384	1121115.AXVN01000051_gene792	0.0	1331.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia,3XZ0C@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	helD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
NHEHCBFB_01385	1121115.AXVN01000051_gene793	9.77e-177	503.0	2EWK9@1|root,33PYD@2|Bacteria,1VTXK@1239|Firmicutes,24ZC9@186801|Clostridia,3Y0MZ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01386	457412.RSAG_02468	2.94e-196	543.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia,3WSIZ@541000|Ruminococcaceae	186801|Clostridia	S	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
NHEHCBFB_01387	1121115.AXVN01000051_gene795	1.91e-203	563.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,3XYXT@572511|Blautia	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
NHEHCBFB_01388	1121115.AXVN01000051_gene796	0.0	1283.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,3XZ2F@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
NHEHCBFB_01389	457412.RSAG_02464	1.72e-88	261.0	COG3976@1|root,COG3976@2|Bacteria,1V72R@1239|Firmicutes,24JFD@186801|Clostridia,3WK5R@541000|Ruminococcaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01390	1121115.AXVN01000051_gene798	0.0	2196.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,3XYMT@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
NHEHCBFB_01391	1121115.AXVN01000051_gene799	0.0	2383.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,3XYPU@572511|Blautia	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
NHEHCBFB_01392	457412.RSAG_02461	0.0	943.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,3WGN3@541000|Ruminococcaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
NHEHCBFB_01393	1121115.AXVN01000051_gene801	2.25e-70	212.0	COG1695@1|root,COG1695@2|Bacteria,1VACN@1239|Firmicutes,24MRF@186801|Clostridia,3Y09J@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
NHEHCBFB_01394	1121115.AXVN01000051_gene802	3.86e-122	353.0	COG4709@1|root,COG4709@2|Bacteria,1VETQ@1239|Firmicutes,24G3G@186801|Clostridia,3Y0B4@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NHEHCBFB_01395	1121115.AXVN01000051_gene803	6.75e-152	436.0	2DN7I@1|root,32VZ1@2|Bacteria,1UJVJ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
NHEHCBFB_01396	1121115.AXVN01000051_gene804	3.56e-38	127.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,3Y0IZ@572511|Blautia	186801|Clostridia	KT	PspC domain	pspC	-	-	-	-	-	-	-	-	-	-	-	PspC
NHEHCBFB_01397	1121115.AXVN01000051_gene805	3.81e-33	115.0	2EIJI@1|root,33CAV@2|Bacteria,1VK5E@1239|Firmicutes,24MMQ@186801|Clostridia,3Y0TE@572511|Blautia	186801|Clostridia	S	COG NOG17864 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	SASP
NHEHCBFB_01398	1235798.C817_02839	1.46e-128	371.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,27VID@189330|Dorea	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
NHEHCBFB_01399	500632.CLONEX_01807	1.99e-214	599.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
NHEHCBFB_01400	1280698.AUJS01000028_gene2283	1.9e-176	496.0	COG1275@1|root,COG1275@2|Bacteria,1UYTE@1239|Firmicutes,2497H@186801|Clostridia	186801|Clostridia	P	C4-dicarboxylate transporter malic acid transport protein	-	-	-	ko:K11041	ko05150,map05150	-	-	-	ko00000,ko00001,ko02042	2.A.16	-	-	SLAC1
NHEHCBFB_01401	1280698.AUJS01000028_gene2282	2.13e-112	323.0	2C91C@1|root,30CC5@2|Bacteria,1V60C@1239|Firmicutes,24HJE@186801|Clostridia	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
NHEHCBFB_01403	1121115.AXVN01000051_gene809	2.73e-189	528.0	COG0791@1|root,COG0791@2|Bacteria,1VICE@1239|Firmicutes,25BYF@186801|Clostridia	186801|Clostridia	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_5,NLPC_P60,SH3_3
NHEHCBFB_01404	1121115.AXVN01000051_gene810	2.29e-70	212.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24UEE@186801|Clostridia	186801|Clostridia	K	helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_01405	1121115.AXVN01000051_gene811	9.34e-130	368.0	2EHNM@1|root,33BEE@2|Bacteria,1VNIH@1239|Firmicutes,24PUV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01406	1121115.AXVN01000051_gene812	4.35e-166	464.0	COG3279@1|root,COG3279@2|Bacteria,1UYV2@1239|Firmicutes,24F5U@186801|Clostridia,3Y1SH@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NHEHCBFB_01407	457412.RSAG_02814	5.57e-80	264.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,24JUC@186801|Clostridia,3WJ4K@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NHEHCBFB_01409	1121115.AXVN01000148_gene3602	2.91e-29	115.0	COG4403@1|root,COG4403@2|Bacteria,1TS6F@1239|Firmicutes,247JU@186801|Clostridia,3XZVN@572511|Blautia	186801|Clostridia	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
NHEHCBFB_01410	457412.RSAG_03505	9.69e-195	545.0	COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,24AH4@186801|Clostridia,3WGYW@541000|Ruminococcaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
NHEHCBFB_01412	457412.RSAG_02966	9.64e-310	846.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WNWQ@541000|Ruminococcaceae	186801|Clostridia	V	MviN-like protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_01413	1121115.AXVN01000035_gene3823	3.32e-166	466.0	COG5438@1|root,COG5438@2|Bacteria,1TSWX@1239|Firmicutes,24AY1@186801|Clostridia,3Y1HG@572511|Blautia	186801|Clostridia	S	YibE/F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
NHEHCBFB_01414	457412.RSAG_02955	3.81e-254	698.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia,3WIF6@541000|Ruminococcaceae	186801|Clostridia	S	PFAM YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
NHEHCBFB_01415	478749.BRYFOR_07883	0.0	1069.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia	186801|Clostridia	G	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
NHEHCBFB_01416	478749.BRYFOR_07882	2.25e-179	501.0	COG0395@1|root,COG0395@2|Bacteria,1UN1I@1239|Firmicutes,249S1@186801|Clostridia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NHEHCBFB_01417	478749.BRYFOR_07881	8.47e-192	535.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NHEHCBFB_01418	478749.BRYFOR_07879	2.24e-259	715.0	COG1653@1|root,COG1653@2|Bacteria,1TRAX@1239|Firmicutes,2497E@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NHEHCBFB_01419	478749.BRYFOR_07878	5.36e-157	454.0	COG1653@1|root,COG1653@2|Bacteria,1TR68@1239|Firmicutes,24BKP@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NHEHCBFB_01420	478749.BRYFOR_07877	9.96e-212	602.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TT52@1239|Firmicutes,249A9@186801|Clostridia	186801|Clostridia	T	COG COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NHEHCBFB_01421	478749.BRYFOR_07876	6.09e-311	861.0	COG2972@1|root,COG2972@2|Bacteria,1TW41@1239|Firmicutes,24AHF@186801|Clostridia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NHEHCBFB_01422	1121115.AXVN01000035_gene3825	6.96e-239	656.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia,3XZ2T@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
NHEHCBFB_01423	457412.RSAG_02951	5.91e-143	404.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia,3WG7B@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
NHEHCBFB_01424	1121115.AXVN01000035_gene3829	4.02e-304	828.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,3XYM5@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
NHEHCBFB_01425	457412.RSAG_02949	1.7e-149	421.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,3WI82@541000|Ruminococcaceae	186801|Clostridia	S	O-methyltransferase	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
NHEHCBFB_01426	1121115.AXVN01000035_gene3831	1.86e-89	262.0	COG1559@1|root,COG1559@2|Bacteria,1VGA6@1239|Firmicutes,24RBR@186801|Clostridia,3Y0GT@572511|Blautia	186801|Clostridia	S	YceG-like family	-	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
NHEHCBFB_01427	1121115.AXVN01000035_gene3832	6.22e-74	221.0	COG3679@1|root,COG3679@2|Bacteria,1VH19@1239|Firmicutes,24RNC@186801|Clostridia,3Y0MG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
NHEHCBFB_01428	457412.RSAG_02946	0.0	1228.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3WH9M@541000|Ruminococcaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
NHEHCBFB_01429	1121115.AXVN01000035_gene3834	4.26e-45	146.0	2E3Y4@1|root,32YV4@2|Bacteria,1VFRH@1239|Firmicutes,24QXW@186801|Clostridia,3Y0M4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
NHEHCBFB_01430	457412.RSAG_02944	1.56e-93	273.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,3WJ8E@541000|Ruminococcaceae	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
NHEHCBFB_01431	1121115.AXVN01000035_gene3836	2.28e-58	180.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,3Y0G3@572511|Blautia	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
NHEHCBFB_01432	457412.RSAG_02942	0.0	870.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,3WG80@541000|Ruminococcaceae	186801|Clostridia	J	tRNA methylthiotransferase YqeV	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
NHEHCBFB_01433	1121115.AXVN01000035_gene3838	2.29e-48	154.0	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,3Y0BS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NHEHCBFB_01434	1121115.AXVN01000035_gene3839	1.25e-284	777.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,3XZ1T@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
NHEHCBFB_01435	457412.RSAG_02939	6.1e-276	754.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3WGVY@541000|Ruminococcaceae	186801|Clostridia	E	aminotransferase class V	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NHEHCBFB_01436	457412.RSAG_02938	7.68e-172	480.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,3WIFN@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
NHEHCBFB_01437	1121115.AXVN01000035_gene3842	3.51e-223	615.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,3XZAN@572511|Blautia	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
NHEHCBFB_01438	457412.RSAG_02936	5.07e-176	489.0	COG0671@1|root,COG0671@2|Bacteria,1V2PZ@1239|Firmicutes,24DHR@186801|Clostridia,3WJNZ@541000|Ruminococcaceae	186801|Clostridia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
NHEHCBFB_01439	1121115.AXVN01000035_gene3844	5.15e-269	738.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,3XYJ6@572511|Blautia	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
NHEHCBFB_01440	1121115.AXVN01000035_gene3845	0.0	1172.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
NHEHCBFB_01441	1121115.AXVN01000035_gene3846	8.91e-136	386.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,3XZX7@572511|Blautia	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
NHEHCBFB_01442	1121115.AXVN01000035_gene3847	4.49e-236	650.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,3XYPX@572511|Blautia	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
NHEHCBFB_01443	457412.RSAG_02931	0.0	1271.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,3WGH5@541000|Ruminococcaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
NHEHCBFB_01444	457412.RSAG_02930	0.0	1744.0	COG0642@1|root,COG0834@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,3WSS0@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,HATPase_c,HisKA,Response_reg,SBP_bac_3,dCache_1
NHEHCBFB_01445	1121115.AXVN01000035_gene3853	6.01e-79	241.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,25C6V@186801|Clostridia,3Y1BG@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_01446	1121115.AXVN01000035_gene3855	2.35e-67	204.0	COG1695@1|root,COG1695@2|Bacteria,1VIVQ@1239|Firmicutes,25CR8@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
NHEHCBFB_01447	1121115.AXVN01000035_gene3856	5.75e-98	290.0	COG4709@1|root,COG4709@2|Bacteria,1VBG6@1239|Firmicutes,24N6S@186801|Clostridia,3Y0AR@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NHEHCBFB_01448	1121115.AXVN01000035_gene3857	4.16e-172	483.0	COG3595@1|root,COG3595@2|Bacteria,1VA9V@1239|Firmicutes,24QYE@186801|Clostridia,3Y0E5@572511|Blautia	186801|Clostridia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
NHEHCBFB_01449	411459.RUMOBE_01989	0.0	1027.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,3XZ52@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NHEHCBFB_01450	411459.RUMOBE_01990	8.81e-139	395.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,3XYJP@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_01451	457412.RSAG_00487	3.39e-121	346.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WJQH@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NHEHCBFB_01452	457412.RSAG_00486	9.61e-249	684.0	2ACB9@1|root,311W7@2|Bacteria,1V49X@1239|Firmicutes,24NF4@186801|Clostridia,3WJZP@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NHEHCBFB_01453	457412.RSAG_00484	7.22e-119	340.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,3WJXC@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NHEHCBFB_01454	457412.RSAG_00483	0.0	924.0	28NHG@1|root,2ZBJ9@2|Bacteria,1V1QG@1239|Firmicutes,24GQ1@186801|Clostridia,3WM85@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NHEHCBFB_01455	1121115.AXVN01000026_gene1018	1.58e-115	340.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3XYNG@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NHEHCBFB_01456	1121115.AXVN01000026_gene1019	1.9e-88	261.0	2A2TB@1|root,30R6U@2|Bacteria,1V47K@1239|Firmicutes,24IKY@186801|Clostridia,3Y1K0@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01457	1121115.AXVN01000004_gene2003	9.28e-113	323.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,3Y0EF@572511|Blautia	186801|Clostridia	K	COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NHEHCBFB_01458	1121115.AXVN01000004_gene2002	0.0	1179.0	2EXAA@1|root,33QKY@2|Bacteria,1VU9D@1239|Firmicutes,24Y4F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01459	457412.RSAG_00476	1.9e-194	540.0	COG1266@1|root,COG1266@2|Bacteria,1USCY@1239|Firmicutes,24F5M@186801|Clostridia,3WMPA@541000|Ruminococcaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
NHEHCBFB_01460	457412.RSAG_00475	7.76e-186	516.0	COG0768@1|root,COG0768@2|Bacteria,1V1CI@1239|Firmicutes,24GWI@186801|Clostridia,3WRJI@541000|Ruminococcaceae	186801|Clostridia	M	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,Peptidase_C70
NHEHCBFB_01461	1121115.AXVN01000004_gene1999	3.54e-166	465.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3Y09B@572511|Blautia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_01462	1121115.AXVN01000004_gene1998	1.34e-302	825.0	COG0642@1|root,COG2205@2|Bacteria,1UYAJ@1239|Firmicutes,24CIQ@186801|Clostridia,3Y01I@572511|Blautia	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,HisKA
NHEHCBFB_01463	515620.EUBELI_20438	3.91e-91	277.0	COG0834@1|root,COG0834@2|Bacteria,1UYKY@1239|Firmicutes,24C0B@186801|Clostridia,25VI4@186806|Eubacteriaceae	186801|Clostridia	ET	substrate-binding protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NHEHCBFB_01464	457412.RSAG_04743	1.83e-113	326.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA,PAS_7,Response_reg
NHEHCBFB_01465	457412.RSAG_00471	5.48e-203	562.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
NHEHCBFB_01466	457412.RSAG_00470	5.91e-102	294.0	COG1943@1|root,COG1943@2|Bacteria,1VAIQ@1239|Firmicutes,24IPG@186801|Clostridia,3WRVG@541000|Ruminococcaceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
NHEHCBFB_01467	1121115.AXVN01000004_gene1990	0.0	889.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24FCE@186801|Clostridia	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605
NHEHCBFB_01468	457412.RSAG_00468	1.79e-68	207.0	COG0784@1|root,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
NHEHCBFB_01469	411459.RUMOBE_01862	1.45e-158	444.0	COG0745@1|root,COG0745@2|Bacteria,1TQSA@1239|Firmicutes,24F54@186801|Clostridia,3Y2DR@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_01470	411459.RUMOBE_01861	0.0	905.0	COG0642@1|root,COG2205@2|Bacteria,1TRD2@1239|Firmicutes,247M3@186801|Clostridia,3Y0A6@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NHEHCBFB_01471	411459.RUMOBE_01860	0.0	960.0	2CGG8@1|root,2ZB3X@2|Bacteria,1TS7C@1239|Firmicutes,24CYW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01472	411459.RUMOBE_01859	3.31e-206	571.0	28ITJ@1|root,2Z8SG@2|Bacteria,1V0TD@1239|Firmicutes,24AI9@186801|Clostridia,3Y182@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01473	457412.RSAG_00463	2.96e-157	442.0	2C82F@1|root,32X5P@2|Bacteria,1VC9W@1239|Firmicutes,24PT0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01474	411459.RUMOBE_01857	2.6e-174	485.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,3XZV2@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_01475	457412.RSAG_00461	3.2e-261	721.0	COG1361@1|root,COG1361@2|Bacteria,1TQHN@1239|Firmicutes,24BUH@186801|Clostridia,3WK3W@541000|Ruminococcaceae	186801|Clostridia	M	COG NOG29868 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
NHEHCBFB_01476	457412.RSAG_00460	4.76e-155	436.0	2CAM3@1|root,33QBQ@2|Bacteria,1VU0Q@1239|Firmicutes,24Y3I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01477	457412.RSAG_00458	7.34e-152	434.0	2E29B@1|root,32XF1@2|Bacteria,1VQT6@1239|Firmicutes,24QIB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01479	457412.RSAG_00456	1.77e-230	636.0	2EEYR@1|root,338S0@2|Bacteria,1VG5B@1239|Firmicutes,25DXF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01480	457412.RSAG_00455	7.26e-147	414.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,3WIM2@541000|Ruminococcaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_01481	457412.RSAG_00452	7.35e-78	246.0	2DPBT@1|root,331F1@2|Bacteria,1UKHY@1239|Firmicutes,25FXG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01482	1121115.AXVN01000002_gene1334	3.56e-28	101.0	2FJB1@1|root,2ZIU3@2|Bacteria,1W6D5@1239|Firmicutes,257AD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01483	457412.RSAG_00434	5.51e-12	63.2	COG3682@1|root,COG3682@2|Bacteria,1VEJ8@1239|Firmicutes,24R6S@186801|Clostridia,3WKEQ@541000|Ruminococcaceae	186801|Clostridia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NHEHCBFB_01484	457412.RSAG_00449	0.0	1233.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,3WGJR@541000|Ruminococcaceae	186801|Clostridia	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
NHEHCBFB_01485	457412.RSAG_00448	0.0	972.0	28N3H@1|root,2ZB96@2|Bacteria,1V5KH@1239|Firmicutes,24I7W@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
NHEHCBFB_01486	457412.RSAG_04742	4.87e-81	239.0	2906S@1|root,2ZMWJ@2|Bacteria,1W4MG@1239|Firmicutes,255KP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01487	457412.RSAG_00447	8.74e-182	505.0	COG0582@1|root,COG0582@2|Bacteria,1V18M@1239|Firmicutes,24BGH@186801|Clostridia,3WI7D@541000|Ruminococcaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NHEHCBFB_01488	457412.RSAG_00446	7.21e-236	648.0	COG4974@1|root,COG4974@2|Bacteria,1W02H@1239|Firmicutes,2547I@186801|Clostridia,3WSNA@541000|Ruminococcaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NHEHCBFB_01489	457412.RSAG_00445	2.6e-166	464.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,3WHJK@541000|Ruminococcaceae	186801|Clostridia	U	TraM recognition site of TraD and TraG	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
NHEHCBFB_01490	457412.RSAG_00444	1.82e-49	156.0	2EFQH@1|root,339GG@2|Bacteria,1VK0J@1239|Firmicutes,24UA1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01491	457412.RSAG_00443	3.97e-229	631.0	2E2IS@1|root,32XNC@2|Bacteria,1VAW0@1239|Firmicutes,24N5A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01492	457412.RSAG_00442	0.0	1571.0	COG1061@1|root,COG1199@1|root,COG1061@2|Bacteria,COG1199@2|Bacteria,1URXJ@1239|Firmicutes,24FDA@186801|Clostridia	186801|Clostridia	KL	HELICc2	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_2,ResIII
NHEHCBFB_01493	457412.RSAG_00441	3.21e-213	589.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WHQU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
NHEHCBFB_01497	457412.RSAG_03284	1.9e-171	478.0	COG0204@1|root,COG0204@2|Bacteria,1TTPK@1239|Firmicutes,24B6K@186801|Clostridia,3WIQF@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
NHEHCBFB_01498	1121115.AXVN01000021_gene1720	4.28e-131	372.0	2BWC2@1|root,33RSK@2|Bacteria,1VS2M@1239|Firmicutes,24YI2@186801|Clostridia,3Y093@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01499	1121115.AXVN01000021_gene1719	0.0	1595.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,3XZN8@572511|Blautia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
NHEHCBFB_01500	1121115.AXVN01000021_gene1718	0.0	1269.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,3XYYE@572511|Blautia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
NHEHCBFB_01501	1121115.AXVN01000021_gene1717	5.91e-198	549.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,3XYJ8@572511|Blautia	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
NHEHCBFB_01502	1121115.AXVN01000021_gene1716	7.15e-176	490.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,3XZ60@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
NHEHCBFB_01503	1121115.AXVN01000021_gene1715	1.7e-205	569.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,3XYM3@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
NHEHCBFB_01504	457412.RSAG_03291	1.15e-234	645.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,3WI7S@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
NHEHCBFB_01505	1121115.AXVN01000021_gene1713	1.6e-140	396.0	COG0194@1|root,COG0194@2|Bacteria,1V3RZ@1239|Firmicutes,24HKC@186801|Clostridia,3XZXN@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	gmk_1	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
NHEHCBFB_01506	1121115.AXVN01000021_gene1712	0.0	958.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3XYX4@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	speA_1	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
NHEHCBFB_01507	1121115.AXVN01000021_gene1711	2.92e-162	454.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,3XYGU@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_01508	1121115.AXVN01000021_gene1710	4.04e-266	729.0	COG5002@1|root,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia,3XZ9P@572511|Blautia	186801|Clostridia	T	COG COG0642 Signal transduction histidine kinase	yycG_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NHEHCBFB_01509	1121115.AXVN01000021_gene1709	4.37e-285	778.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3XZ7D@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
NHEHCBFB_01510	1121115.AXVN01000021_gene1708	1.35e-300	821.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3XZ1V@572511|Blautia	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
NHEHCBFB_01511	1121115.AXVN01000021_gene1707	6.42e-112	322.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia,3Y00E@572511|Blautia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
NHEHCBFB_01512	457412.RSAG_03298	2.35e-138	391.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,3WIF0@541000|Ruminococcaceae	186801|Clostridia	S	Flavin reductase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NHEHCBFB_01513	457412.RSAG_03299	0.0	1078.0	COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,3WGK7@541000|Ruminococcaceae	186801|Clostridia	C	CBS domain	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
NHEHCBFB_01514	1121115.AXVN01000021_gene1704	1.14e-200	557.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia,3XZE6@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
NHEHCBFB_01515	1121115.AXVN01000021_gene1703	9.78e-156	437.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,3XZH1@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	spoT	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NHEHCBFB_01516	1121115.AXVN01000021_gene1702	3.71e-90	265.0	2EY21@1|root,33RAZ@2|Bacteria,1VSPZ@1239|Firmicutes,24YUD@186801|Clostridia,3Y1ZI@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
NHEHCBFB_01517	1121115.AXVN01000021_gene1701	3.77e-217	599.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3XZGB@572511|Blautia	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
NHEHCBFB_01518	457412.RSAG_03304	0.0	1456.0	COG0457@1|root,COG0464@1|root,COG0457@2|Bacteria,COG0464@2|Bacteria,1TY3C@1239|Firmicutes,248IE@186801|Clostridia,3WGDF@541000|Ruminococcaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	SpoVK	-	-	-	-	-	-	-	-	-	-	-	TPR_8
NHEHCBFB_01519	1121115.AXVN01000021_gene1699	2.51e-261	716.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3XZEV@572511|Blautia	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
NHEHCBFB_01520	1121115.AXVN01000021_gene1698	4.45e-42	137.0	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,3Y0NB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
NHEHCBFB_01521	457412.RSAG_03307	4.51e-260	713.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,3WGZ2@541000|Ruminococcaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
NHEHCBFB_01522	1121115.AXVN01000021_gene1696	0.0	889.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,3XYQ0@572511|Blautia	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
NHEHCBFB_01523	457412.RSAG_03309	1.37e-21	84.3	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,3WM8B@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
NHEHCBFB_01524	457412.RSAG_03310	6.74e-80	237.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,3WKGV@541000|Ruminococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
NHEHCBFB_01525	457412.RSAG_03311	1.52e-47	151.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,3WKGN@541000|Ruminococcaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
NHEHCBFB_01526	457412.RSAG_03312	7.92e-289	791.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,3WHYT@541000|Ruminococcaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
NHEHCBFB_01527	1121115.AXVN01000021_gene1693	1.9e-190	532.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3XZCW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
NHEHCBFB_01528	457412.RSAG_03314	0.0	875.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,3WGHG@541000|Ruminococcaceae	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
NHEHCBFB_01529	1121115.AXVN01000021_gene1691	0.0	1217.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,3XYJA@572511|Blautia	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
NHEHCBFB_01530	457412.RSAG_03316	2.8e-170	475.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,3WIRQ@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
NHEHCBFB_01531	457412.RSAG_03317	2.64e-245	675.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,3WH5S@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_01532	1121115.AXVN01000021_gene1688	1.03e-184	516.0	COG1277@1|root,COG1277@2|Bacteria,1UZXS@1239|Firmicutes,248ME@186801|Clostridia,3XYVG@572511|Blautia	186801|Clostridia	N	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3,ABC2_membrane_5
NHEHCBFB_01533	457412.RSAG_03319	0.0	943.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia,3WIU9@541000|Ruminococcaceae	186801|Clostridia	N	transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_transp_aux
NHEHCBFB_01534	457412.RSAG_03320	0.0	898.0	2DN2J@1|root,32V6S@2|Bacteria,1V1QE@1239|Firmicutes,25HR2@186801|Clostridia,3WKKB@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
NHEHCBFB_01535	457412.RSAG_02982	2.41e-111	319.0	2AJD7@1|root,319YQ@2|Bacteria,1V83F@1239|Firmicutes,24FWU@186801|Clostridia,3WP2T@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01536	742765.HMPREF9457_00651	2.36e-149	419.0	COG1073@1|root,COG1073@2|Bacteria,1U9AI@1239|Firmicutes,24B6Z@186801|Clostridia,27WE4@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
NHEHCBFB_01537	457412.RSAG_00859	9.99e-86	252.0	2DH0B@1|root,2ZXXZ@2|Bacteria,1W4MJ@1239|Firmicutes,257EH@186801|Clostridia	457412.RSAG_00859|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01538	457412.RSAG_00858	1.6e-290	793.0	COG0738@1|root,COG0738@2|Bacteria,1TQPE@1239|Firmicutes,24AF8@186801|Clostridia,3WHA7@541000|Ruminococcaceae	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NHEHCBFB_01539	1121115.AXVN01000045_gene2055	8.02e-220	606.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1V0PV@1239|Firmicutes,24BUX@186801|Clostridia,3Y136@572511|Blautia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
NHEHCBFB_01540	457412.RSAG_00856	0.0	1050.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,3WGG6@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
NHEHCBFB_01541	1121115.AXVN01000045_gene2057	1.52e-154	436.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,3XZ8P@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
NHEHCBFB_01542	457412.RSAG_00854	1.3e-154	434.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WIW5@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
NHEHCBFB_01543	1121115.AXVN01000045_gene2059	0.0	1665.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Response_reg
NHEHCBFB_01544	1121115.AXVN01000045_gene2062	4.06e-245	674.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,3XZHK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NMO
NHEHCBFB_01545	1121115.AXVN01000045_gene2063	3.94e-307	839.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3XYPM@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_01546	1121115.AXVN01000045_gene2064	9.57e-176	491.0	2DM3M@1|root,31JZR@2|Bacteria,1V8CM@1239|Firmicutes,24KFB@186801|Clostridia	186801|Clostridia	M	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NHEHCBFB_01547	457412.RSAG_00848	0.0	2368.0	2C1EE@1|root,2Z86R@2|Bacteria,1TS39@1239|Firmicutes,24ABS@186801|Clostridia,3WH59@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	Rnd	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01548	457412.RSAG_00847	4.42e-312	848.0	28MVQ@1|root,2ZB38@2|Bacteria,1UUTH@1239|Firmicutes,24AV8@186801|Clostridia,3WK5B@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01549	1121115.AXVN01000045_gene2067	3.25e-181	505.0	2B4WY@1|root,31XPQ@2|Bacteria,1V739@1239|Firmicutes,24IHF@186801|Clostridia,3Y2D0@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01550	1121115.AXVN01000045_gene2068	4.74e-191	533.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3XYR5@572511|Blautia	186801|Clostridia	ET	cystine-binding periplasmic protein precursor	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NHEHCBFB_01551	1121115.AXVN01000045_gene2069	8.52e-135	384.0	COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,25C2S@186801|Clostridia,3XYV9@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	tcyB	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
NHEHCBFB_01552	1121115.AXVN01000045_gene2070	2.04e-157	442.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3XZJ5@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
NHEHCBFB_01553	1121115.AXVN01000045_gene2071	0.0	930.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3XZ1Q@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
NHEHCBFB_01554	457412.RSAG_00842	0.0	872.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3WGUF@541000|Ruminococcaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
NHEHCBFB_01555	1121115.AXVN01000045_gene2073	6.42e-198	548.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia,3XZZB@572511|Blautia	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
NHEHCBFB_01556	1121115.AXVN01000006_gene2188	1.25e-123	352.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia,3XZU8@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
NHEHCBFB_01557	457412.RSAG_00839	1.9e-121	347.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia	186801|Clostridia	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
NHEHCBFB_01558	1121115.AXVN01000006_gene2186	3.38e-208	576.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3XYQC@572511|Blautia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
NHEHCBFB_01559	1121115.AXVN01000006_gene2185	1.13e-204	566.0	29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,24HI3@186801|Clostridia,3Y05C@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	spoIIGA	-	-	ko:K06383	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_U4
NHEHCBFB_01560	1121115.AXVN01000006_gene2184	5.6e-159	446.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,3XZGI@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
NHEHCBFB_01561	457412.RSAG_00835	7.43e-241	662.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia,3WHUE@541000|Ruminococcaceae	186801|Clostridia	C	pyruvate formate lyase activating	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NHEHCBFB_01562	1121115.AXVN01000006_gene2182	0.0	919.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,3XYTG@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NHEHCBFB_01563	457412.RSAG_00833	0.0	868.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,3WGP4@541000|Ruminococcaceae	186801|Clostridia	P	K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NHEHCBFB_01565	411459.RUMOBE_02489	0.0	1921.0	COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,24AX1@186801|Clostridia,3Y1AM@572511|Blautia	186801|Clostridia	M	LPXTG-motif cell wall anchor domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01566	411459.RUMOBE_02490	2.94e-71	214.0	2BXTH@1|root,2ZZ52@2|Bacteria,1V3TU@1239|Firmicutes,24I3V@186801|Clostridia,3Y1M3@572511|Blautia	186801|Clostridia	S	COG NOG10998 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
NHEHCBFB_01567	411459.RUMOBE_02491	3.56e-86	253.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,24IAF@186801|Clostridia,3Y1IN@572511|Blautia	186801|Clostridia	S	COG NOG13239 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
NHEHCBFB_01568	411459.RUMOBE_02492	0.0	917.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,3Y1AZ@572511|Blautia	186801|Clostridia	D	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
NHEHCBFB_01569	411459.RUMOBE_02493	1.57e-298	814.0	COG2946@1|root,COG2946@2|Bacteria,1UHNT@1239|Firmicutes,24ZUP@186801|Clostridia,3Y18K@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31,Rep_trans
NHEHCBFB_01570	471875.RUMLAC_01426	1.66e-22	86.7	2DZ2V@1|root,34C88@2|Bacteria,1W361@1239|Firmicutes,254XY@186801|Clostridia,3WQT4@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3789)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3789
NHEHCBFB_01571	411459.RUMOBE_02495	1.69e-41	136.0	2C9BX@1|root,32RP2@2|Bacteria,1VANR@1239|Firmicutes,24N4I@186801|Clostridia,3Y0EY@572511|Blautia	186801|Clostridia	S	COG NOG13238 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01572	411461.DORFOR_02736	2.37e-115	330.0	COG4734@1|root,COG4734@2|Bacteria,1UZZ6@1239|Firmicutes,24DE1@186801|Clostridia	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NHEHCBFB_01573	411459.RUMOBE_02498	4.75e-117	335.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249HA@186801|Clostridia,3Y1DJ@572511|Blautia	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NHEHCBFB_01574	457412.RSAG_00816	7.42e-89	260.0	28I70@1|root,2Z89W@2|Bacteria,1V1TC@1239|Firmicutes,24FQV@186801|Clostridia,3WIZ3@541000|Ruminococcaceae	186801|Clostridia	S	TcpE family	-	-	-	-	-	-	-	-	-	-	-	-	TcpE
NHEHCBFB_01575	411459.RUMOBE_02501	0.0	1497.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,24AAP@186801|Clostridia,3XZG4@572511|Blautia	186801|Clostridia	S	COG NOG05968 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
NHEHCBFB_01576	457412.RSAG_00814	0.0	1175.0	COG3064@1|root,COG3064@2|Bacteria,1UIYZ@1239|Firmicutes,249MX@186801|Clostridia,3WGQV@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01577	411461.DORFOR_02742	5.33e-243	667.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,27WJ1@189330|Dorea	186801|Clostridia	M	Lysozyme-like	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
NHEHCBFB_01578	457412.RSAG_00812	9.5e-208	575.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia,3WI6V@541000|Ruminococcaceae	186801|Clostridia	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
NHEHCBFB_01579	457412.RSAG_00811	1.45e-164	459.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,3WIJ0@541000|Ruminococcaceae	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_01580	457412.RSAG_00810	0.0	870.0	COG0642@1|root,COG2205@2|Bacteria,1TRZX@1239|Firmicutes,249AI@186801|Clostridia,3WIVN@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NHEHCBFB_01581	457412.RSAG_00809	2.84e-115	330.0	29UU9@1|root,30G6R@2|Bacteria,1UFAI@1239|Firmicutes,24D25@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01582	457412.RSAG_00808	4.27e-37	124.0	2DP5Q@1|root,330MY@2|Bacteria,1VFAQ@1239|Firmicutes,24R7E@186801|Clostridia,3WKJD@541000|Ruminococcaceae	186801|Clostridia	S	Cysteine-rich KTR	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_KTR
NHEHCBFB_01583	457412.RSAG_00807	1.23e-75	226.0	COG1396@1|root,COG1396@2|Bacteria,1V50Y@1239|Firmicutes,24HFJ@186801|Clostridia,3WJZF@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_01584	457412.RSAG_00806	2.06e-93	273.0	COG1191@1|root,COG1191@2|Bacteria,1UJ7B@1239|Firmicutes,24KND@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sigma70_r4_2
NHEHCBFB_01585	457412.RSAG_00805	1.48e-49	157.0	2AJW5@1|root,32RUV@2|Bacteria,1UHK2@1239|Firmicutes	1239|Firmicutes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NHEHCBFB_01586	457412.RSAG_00804	9.12e-28	100.0	2EJDE@1|root,33D4F@2|Bacteria,1VMA3@1239|Firmicutes,24X75@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01587	457412.RSAG_00803	0.0	1036.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3WGP9@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NHEHCBFB_01588	457412.RSAG_00802	3.11e-84	248.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,3WHS3@541000|Ruminococcaceae	186801|Clostridia	P	PFAM Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
NHEHCBFB_01589	457412.RSAG_00801	0.0	913.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia,3WIPD@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NHEHCBFB_01590	457412.RSAG_00800	1.69e-130	370.0	COG4636@1|root,COG4636@2|Bacteria,1VWXI@1239|Firmicutes,24ES8@186801|Clostridia,3WK7K@541000|Ruminococcaceae	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NHEHCBFB_01591	457412.RSAG_00799	1.63e-196	545.0	2F0QG@1|root,33TSW@2|Bacteria,1VV31@1239|Firmicutes,2502Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01592	1121115.AXVN01000006_gene2176	9.96e-71	214.0	COG2856@1|root,COG2856@2|Bacteria,1V4N6@1239|Firmicutes,24JDG@186801|Clostridia,3Y0M2@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
NHEHCBFB_01593	1121115.AXVN01000006_gene2175	2.73e-50	159.0	arCOG06833@1|root,32SGF@2|Bacteria,1U5WJ@1239|Firmicutes,25K3K@186801|Clostridia,3Y0UZ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01594	457412.RSAG_00796	2.84e-73	219.0	arCOG07672@1|root,32Z5Y@2|Bacteria,1VG6R@1239|Firmicutes,24T0M@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
NHEHCBFB_01595	457412.RSAG_00795	5.35e-113	324.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	HTH_3,HTH_31,PAS_3
NHEHCBFB_01596	457412.RSAG_00794	1.28e-49	157.0	COG3655@1|root,COG3655@2|Bacteria,1VHGA@1239|Firmicutes,24VPG@186801|Clostridia	186801|Clostridia	K	Protein of unknown function (DUF739)	-	-	-	-	-	-	-	-	-	-	-	-	DUF739
NHEHCBFB_01597	1121115.AXVN01000006_gene2172	8.37e-28	100.0	2FGK7@1|root,348FZ@2|Bacteria,1W09F@1239|Firmicutes,25375@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01598	1121115.AXVN01000006_gene2171	1.7e-59	184.0	2CJIG@1|root,32SA4@2|Bacteria,1VCKV@1239|Firmicutes,24P9C@186801|Clostridia,3Y0FM@572511|Blautia	186801|Clostridia	S	Phage holin family Hol44, in holin superfamily V	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_5_2
NHEHCBFB_01599	1121115.AXVN01000006_gene2170	0.0	986.0	COG3409@1|root,COG3757@1|root,COG3409@2|Bacteria,COG3757@2|Bacteria,1VDIK@1239|Firmicutes,25FZ8@186801|Clostridia,3Y00U@572511|Blautia	186801|Clostridia	M	autolytic lysozime (1,4-beta-N-acetylmuramidase), family 25 of glycosyl hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Glyco_hydro_25
NHEHCBFB_01600	411459.RUMOBE_00968	1.17e-17	73.9	COG3546@1|root,COG3546@2|Bacteria,1UF7I@1239|Firmicutes,25K8A@186801|Clostridia,3Y21Y@572511|Blautia	186801|Clostridia	P	Manganese containing catalase	-	-	-	-	-	-	-	-	-	-	-	-	Mn_catalase
NHEHCBFB_01601	1121115.AXVN01000006_gene2169	1.35e-64	196.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia,3Y0NH@572511|Blautia	186801|Clostridia	S	COG NOG18028 non supervised orthologous group	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
NHEHCBFB_01602	1121115.AXVN01000006_gene2168	8.05e-51	162.0	2EHCX@1|root,33B4S@2|Bacteria,1VKA0@1239|Firmicutes,259R7@186801|Clostridia,3Y0T8@572511|Blautia	186801|Clostridia	S	Spore coat associated protein JA (CotJA)	-	-	-	-	-	-	-	-	-	-	-	-	CotJA
NHEHCBFB_01603	1121115.AXVN01000006_gene2167	1.41e-201	556.0	COG1234@1|root,COG1234@2|Bacteria,1TPSW@1239|Firmicutes,249RR@186801|Clostridia,3XYRY@572511|Blautia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
NHEHCBFB_01604	1121115.AXVN01000006_gene2166	4.17e-157	440.0	COG1309@1|root,COG1309@2|Bacteria,1V3ZS@1239|Firmicutes,24H9U@186801|Clostridia,3XZV5@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NHEHCBFB_01605	1121115.AXVN01000006_gene2165	0.0	1301.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,3XYKA@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
NHEHCBFB_01606	1121115.AXVN01000006_gene2164	6.32e-257	755.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,3XYKM@572511|Blautia	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
NHEHCBFB_01607	457412.RSAG_00783	2.64e-268	736.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WHWW@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
NHEHCBFB_01608	1121115.AXVN01000006_gene2162	1.02e-46	150.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3Y0HG@572511|Blautia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NHEHCBFB_01609	1121115.AXVN01000006_gene2161	4.22e-214	592.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3XZKW@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
NHEHCBFB_01610	1121115.AXVN01000006_gene2160	1.37e-164	461.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3XYM7@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
NHEHCBFB_01611	457412.RSAG_00779	6.9e-298	812.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WGGB@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
NHEHCBFB_01612	1121115.AXVN01000006_gene2158	3.29e-99	288.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,3Y0FB@572511|Blautia	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iHN637.CLJU_RS20755	Biotin_lipoyl
NHEHCBFB_01613	1121115.AXVN01000006_gene2157	1.74e-96	281.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,3Y04Q@572511|Blautia	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
NHEHCBFB_01614	1121115.AXVN01000006_gene2156	0.0	887.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,3XZMB@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
NHEHCBFB_01615	457412.RSAG_00775	0.0	1116.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,3WGZ8@541000|Ruminococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
NHEHCBFB_01616	1121115.AXVN01000006_gene2154	0.0	976.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3XZIU@572511|Blautia	186801|Clostridia	H	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
NHEHCBFB_01617	457412.RSAG_00773	0.0	1158.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,3WGMT@541000|Ruminococcaceae	186801|Clostridia	L	helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
NHEHCBFB_01618	1121115.AXVN01000006_gene2152	2.8e-135	382.0	COG2091@1|root,COG2091@2|Bacteria,1UFUD@1239|Firmicutes,25MRV@186801|Clostridia,3Y03Q@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
NHEHCBFB_01619	1121115.AXVN01000006_gene2151	1.28e-265	727.0	COG3391@1|root,COG3391@2|Bacteria,1V841@1239|Firmicutes,24K83@186801|Clostridia,3Y0X1@572511|Blautia	186801|Clostridia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01620	457412.RSAG_00770	6.69e-239	655.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,3WGH3@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
NHEHCBFB_01621	1121115.AXVN01000006_gene2149	4.35e-120	343.0	2CEWW@1|root,3181X@2|Bacteria,1U7IP@1239|Firmicutes,2590I@186801|Clostridia,3Y0MY@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06391	-	-	-	-	ko00000	-	-	-	Spore_III_AB
NHEHCBFB_01622	457412.RSAG_00768	9.49e-35	119.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,3WKGF@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
NHEHCBFB_01623	1121115.AXVN01000006_gene2147	1.25e-80	240.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia,3Y0FF@572511|Blautia	186801|Clostridia	S	COG NOG13205 non supervised orthologous group	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
NHEHCBFB_01624	457412.RSAG_00766	7.57e-269	739.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia,3WITJ@541000|Ruminococcaceae	186801|Clostridia	S	Stage III sporulation protein	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
NHEHCBFB_01625	457412.RSAG_00765	9.6e-125	356.0	29TPZ@1|root,30EY4@2|Bacteria,1UD4F@1239|Firmicutes,2591T@186801|Clostridia,3WMKP@541000|Ruminococcaceae	186801|Clostridia	S	Stage III sporulation protein AF (Spore_III_AF)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_III_AF
NHEHCBFB_01626	1121115.AXVN01000006_gene2144	2.93e-64	197.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia,3Y0J8@572511|Blautia	186801|Clostridia	S	COG NOG11553 non supervised orthologous group	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
NHEHCBFB_01627	457412.RSAG_00763	4.89e-160	450.0	2E3US@1|root,32YS3@2|Bacteria,1VESK@1239|Firmicutes,24R9H@186801|Clostridia,3WITN@541000|Ruminococcaceae	186801|Clostridia	S	SpoIIIAH-like protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
NHEHCBFB_01628	457412.RSAG_00762	0.0	1053.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,3WGUR@541000|Ruminococcaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
NHEHCBFB_01629	1121115.AXVN01000006_gene2141	8.03e-79	235.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,3Y075@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
NHEHCBFB_01630	1121115.AXVN01000006_gene2140	5.6e-73	219.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,3Y08R@572511|Blautia	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
NHEHCBFB_01631	457412.RSAG_00759	2.88e-273	750.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,3WGCP@541000|Ruminococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
NHEHCBFB_01632	457412.RSAG_00758	2.03e-47	152.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia,3WMSQ@541000|Ruminococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
NHEHCBFB_01633	457412.RSAG_00757	7.21e-205	567.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,3WINP@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
NHEHCBFB_01634	1121115.AXVN01000006_gene2136	0.0	1234.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3XYQF@572511|Blautia	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
NHEHCBFB_01635	457412.RSAG_00755	5.27e-194	538.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3WGGG@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
NHEHCBFB_01636	1121115.AXVN01000006_gene2134	5.1e-205	567.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,3XZAI@572511|Blautia	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
NHEHCBFB_01637	457412.RSAG_00753	6.17e-99	288.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,3WJZ0@541000|Ruminococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
NHEHCBFB_01638	457412.RSAG_00752	0.0	1010.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3WHDP@541000|Ruminococcaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
NHEHCBFB_01639	1121115.AXVN01000006_gene2131	5.39e-292	797.0	COG3480@1|root,COG3480@2|Bacteria,1UI0S@1239|Firmicutes,25E9E@186801|Clostridia,3XZ8A@572511|Blautia	186801|Clostridia	T	stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
NHEHCBFB_01640	457412.RSAG_00750	6.11e-188	522.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia,3WGU4@541000|Ruminococcaceae	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
NHEHCBFB_01641	1121115.AXVN01000006_gene2129	0.0	1001.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3XYMY@572511|Blautia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
NHEHCBFB_01642	1121115.AXVN01000006_gene2128	3.38e-251	689.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3XZ9Q@572511|Blautia	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
NHEHCBFB_01643	457412.RSAG_00747	4.55e-131	372.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia,3WM72@541000|Ruminococcaceae	186801|Clostridia	S	RecX family	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
NHEHCBFB_01644	457412.RSAG_00746	2.79e-299	825.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,3WGE5@541000|Ruminococcaceae	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
NHEHCBFB_01645	457412.RSAG_00744	6.99e-136	385.0	2DUTP@1|root,33S73@2|Bacteria,1US3V@1239|Firmicutes,25A29@186801|Clostridia,3WR2A@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01646	457412.RSAG_00743	7.57e-211	582.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WHQU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
NHEHCBFB_01647	1121115.AXVN01000006_gene2123	1.74e-252	692.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,3XYX3@572511|Blautia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
NHEHCBFB_01648	457412.RSAG_00741	2.46e-305	834.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,3WGTJ@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
NHEHCBFB_01649	1121115.AXVN01000006_gene2121	1.09e-104	303.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3Y0AW@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NHEHCBFB_01650	1121115.AXVN01000006_gene2120	3.19e-283	774.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XZ67@572511|Blautia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NHEHCBFB_01651	1121115.AXVN01000006_gene2119	6.48e-104	300.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3XZVP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
NHEHCBFB_01652	457412.RSAG_00737	0.0	1579.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3WHCP@541000|Ruminococcaceae	186801|Clostridia	P	E1-E2 ATPase	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
NHEHCBFB_01653	457412.RSAG_04756	0.0	1305.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WH4U@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain	ams	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
NHEHCBFB_01654	457412.RSAG_00734	4.73e-203	561.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,3WHRZ@541000|Ruminococcaceae	186801|Clostridia	E	histidinol phosphate phosphatase HisJ family	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
NHEHCBFB_01655	1121115.AXVN01000006_gene2115	2.84e-240	660.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
NHEHCBFB_01656	457412.RSAG_00732	2.17e-287	785.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate kinase	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
NHEHCBFB_01657	1121115.AXVN01000006_gene2113	9.02e-176	490.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3XYGS@572511|Blautia	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
NHEHCBFB_01658	1121115.AXVN01000006_gene2112	1.08e-291	795.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3XZS4@572511|Blautia	186801|Clostridia	J	tRNA (Uracil-5-)-methyltransferase	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
NHEHCBFB_01659	1121115.AXVN01000006_gene2111	1.83e-116	332.0	COG0454@1|root,COG0456@2|Bacteria,1V6Z8@1239|Firmicutes,24JT6@186801|Clostridia,3Y06X@572511|Blautia	186801|Clostridia	K	COG COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NHEHCBFB_01660	1121115.AXVN01000006_gene2110	0.0	915.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,3XZRA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
NHEHCBFB_01661	457412.RSAG_00727	1.15e-39	131.0	COG3655@1|root,COG3655@2|Bacteria,1TU95@1239|Firmicutes,25804@186801|Clostridia,3WQZ7@541000|Ruminococcaceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
NHEHCBFB_01662	457412.RSAG_00726	3.32e-56	174.0	2C1AP@1|root,33ZCD@2|Bacteria,1VYDT@1239|Firmicutes,2529X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01663	1121115.AXVN01000006_gene2107	5.8e-307	837.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3XZMY@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
NHEHCBFB_01664	457412.RSAG_00723	0.0	1030.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3WGBI@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
NHEHCBFB_01665	1121115.AXVN01000006_gene2105	4.41e-305	833.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZQ9@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_01666	1121115.AXVN01000006_gene2104	0.0	1046.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3XYNG@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NHEHCBFB_01667	1121115.AXVN01000006_gene2103	7.1e-44	144.0	2DWAP@1|root,33ZBJ@2|Bacteria,1VWWH@1239|Firmicutes,25203@186801|Clostridia,3Y23P@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
NHEHCBFB_01668	1121115.AXVN01000006_gene2102	5.85e-251	689.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,3XZJ1@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
NHEHCBFB_01669	457412.RSAG_00718	3.34e-243	668.0	COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,248F2@186801|Clostridia,3WSRI@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase like family 2	kfoC_2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NHEHCBFB_01670	457412.RSAG_00717	2.92e-161	451.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,3WJUP@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
NHEHCBFB_01671	457412.RSAG_00716	3.04e-156	438.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24EFS@186801|Clostridia,3WRPD@541000|Ruminococcaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_01672	1121115.AXVN01000061_gene488	0.0	1449.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3XYQH@572511|Blautia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
NHEHCBFB_01673	1121115.AXVN01000061_gene489	3.87e-80	238.0	2DRY9@1|root,33DNC@2|Bacteria,1VJXZ@1239|Firmicutes,25NY6@186801|Clostridia,3Y0SG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01674	457412.RSAG_00713	8.36e-154	432.0	COG0727@1|root,COG0727@2|Bacteria,1TT6P@1239|Firmicutes,24BWS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
NHEHCBFB_01675	1121115.AXVN01000061_gene498	1.2e-306	833.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,3XYMM@572511|Blautia	186801|Clostridia	S	N-methylation of lysine residues in flagellin	fliU	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
NHEHCBFB_01676	457412.RSAG_00704	1.08e-182	510.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,3WIGP@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NHEHCBFB_01677	1121115.AXVN01000061_gene500	0.0	1436.0	COG5426@1|root,COG5426@2|Bacteria,1TPH0@1239|Firmicutes,24892@186801|Clostridia,3XZ5G@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	gnpA	GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704	2.4.1.211	ko:K15533	-	-	-	-	ko00000,ko01000	-	-	-	LBP_C,LBP_M,Lact_bio_phlase
NHEHCBFB_01678	457412.RSAG_00702	7.46e-259	709.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
NHEHCBFB_01679	1121115.AXVN01000043_gene3360	0.0	956.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3XYH4@572511|Blautia	186801|Clostridia	O	AAA domain (dynein-related subfamily)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA
NHEHCBFB_01680	457412.RSAG_00700	2.73e-263	722.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,3WG7W@541000|Ruminococcaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
NHEHCBFB_01681	457412.RSAG_00699	5.25e-149	419.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,3WIGR@541000|Ruminococcaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
NHEHCBFB_01682	457412.RSAG_00698	2.27e-290	792.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,3WGA9@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
NHEHCBFB_01683	1121115.AXVN01000043_gene3364	5.25e-106	306.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,3XZWN@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
NHEHCBFB_01684	457412.RSAG_00696	4.42e-249	684.0	COG0564@1|root,COG0564@2|Bacteria,1VS66@1239|Firmicutes,25M7T@186801|Clostridia,3WP3U@541000|Ruminococcaceae	186801|Clostridia	J	RNA pseudouridylate synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
NHEHCBFB_01685	457412.RSAG_00695	1.05e-221	611.0	COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,249UK@186801|Clostridia,3WGSB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
NHEHCBFB_01686	1121115.AXVN01000043_gene3367	0.0	1067.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,3XYJY@572511|Blautia	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
NHEHCBFB_01687	1121115.AXVN01000043_gene3368	1.78e-148	421.0	2E03H@1|root,333DZ@2|Bacteria,1VJ8Q@1239|Firmicutes,24RNP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01688	1121115.AXVN01000043_gene3369	4.23e-76	227.0	COG1393@1|root,COG1393@2|Bacteria,1V6H8@1239|Firmicutes,24JH6@186801|Clostridia,3Y07N@572511|Blautia	186801|Clostridia	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC,Glutaredoxin
NHEHCBFB_01689	457412.RSAG_00691	1.59e-241	664.0	COG4637@1|root,COG4637@2|Bacteria,1V0EX@1239|Firmicutes,24B14@186801|Clostridia,3WIPF@541000|Ruminococcaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
NHEHCBFB_01690	457412.RSAG_00689	5.87e-109	313.0	COG4728@1|root,COG4728@2|Bacteria,1VENJ@1239|Firmicutes,24SFD@186801|Clostridia,3WMPN@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
NHEHCBFB_01691	457412.RSAG_00688	8.11e-121	345.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24HQM@186801|Clostridia,3WJG3@541000|Ruminococcaceae	186801|Clostridia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
NHEHCBFB_01692	1121115.AXVN01000043_gene3374	2.01e-141	399.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,3XZZD@572511|Blautia	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
NHEHCBFB_01693	1121115.AXVN01000043_gene3375	6.6e-143	403.0	COG2227@1|root,COG2227@2|Bacteria,1V1MT@1239|Firmicutes,24FTN@186801|Clostridia,3Y29B@572511|Blautia	186801|Clostridia	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,NUDIX
NHEHCBFB_01694	1121115.AXVN01000043_gene3376	0.0	1466.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
NHEHCBFB_01695	457412.RSAG_00684	2.6e-14	70.5	28N02@1|root,2ZB6N@2|Bacteria,1UZ98@1239|Firmicutes,24FB2@186801|Clostridia,3WNNW@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01696	457412.RSAG_00684	5.78e-148	421.0	28N02@1|root,2ZB6N@2|Bacteria,1UZ98@1239|Firmicutes,24FB2@186801|Clostridia,3WNNW@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01697	936574.HMPREF1508_0650	9.08e-242	685.0	COG1195@1|root,COG3593@1|root,COG1195@2|Bacteria,COG3593@2|Bacteria,1TVDV@1239|Firmicutes,25DHX@186801|Clostridia	186801|Clostridia	L	ATP-dependent endonuclease of the OLD family	-	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	AAA_15
NHEHCBFB_01698	936574.HMPREF1508_0649	4.45e-214	610.0	COG0210@1|root,COG0210@2|Bacteria,1W75Q@1239|Firmicutes,24SIM@186801|Clostridia	186801|Clostridia	L	UvrD/REP helicase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase
NHEHCBFB_01699	1094508.Tsac_2454	8.4e-174	518.0	COG0323@1|root,COG0323@2|Bacteria,1VSSE@1239|Firmicutes,24ZJR@186801|Clostridia	186801|Clostridia	L	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
NHEHCBFB_01700	1121115.AXVN01000043_gene3383	7.95e-163	459.0	COG0300@1|root,COG0300@2|Bacteria,1UHN7@1239|Firmicutes,25FVQ@186801|Clostridia	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
NHEHCBFB_01701	1121115.AXVN01000043_gene3384	8.05e-26	105.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3Y131@572511|Blautia	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NHEHCBFB_01702	457412.RSAG_00888	7.26e-39	135.0	COG0716@1|root,COG1145@1|root,COG0716@2|Bacteria,COG1145@2|Bacteria,1VSX9@1239|Firmicutes,24ZRM@186801|Clostridia,3WSJJ@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Flavodoxin_5
NHEHCBFB_01703	397291.C804_00209	1.01e-165	473.0	COG0258@1|root,COG0258@2|Bacteria,1UYXU@1239|Firmicutes,248E2@186801|Clostridia,27RU4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	5'-3' exonuclease, N-terminal resolvase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
NHEHCBFB_01704	1280698.AUJS01000002_gene2785	8.51e-267	732.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,27WNM@189330|Dorea	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	adh	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NHEHCBFB_01705	1519439.JPJG01000022_gene567	1.65e-41	136.0	2E7X8@1|root,332BT@2|Bacteria,1VG5Y@1239|Firmicutes,24RJD@186801|Clostridia,2N8Q9@216572|Oscillospiraceae	186801|Clostridia	S	Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
NHEHCBFB_01706	748224.HMPREF9436_03248	1.36e-15	70.9	COG2768@1|root,COG2768@2|Bacteria,1UIUV@1239|Firmicutes,25ESR@186801|Clostridia,3WSJD@541000|Ruminococcaceae	186801|Clostridia	C	formylmethanofuran dehydrogenase subunit F, ferredoxin containing	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_6
NHEHCBFB_01707	1519439.JPJG01000022_gene565	5.6e-137	387.0	COG0348@1|root,COG0348@2|Bacteria,1UHUA@1239|Firmicutes,24BED@186801|Clostridia,2N68B@216572|Oscillospiraceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
NHEHCBFB_01708	748224.HMPREF9436_03246	1.47e-66	202.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3WJVA@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NHEHCBFB_01709	1519439.JPJG01000022_gene563	7.66e-188	536.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,2N6UE@216572|Oscillospiraceae	186801|Clostridia	P	Rhodanese Homology Domain	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
NHEHCBFB_01710	1519439.JPJG01000022_gene563	1.28e-151	440.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,2N6UE@216572|Oscillospiraceae	186801|Clostridia	P	Rhodanese Homology Domain	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
NHEHCBFB_01711	748224.HMPREF9436_03244	7.04e-146	412.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,3WIP0@541000|Ruminococcaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NHEHCBFB_01712	1519439.JPJG01000022_gene562	7.36e-89	261.0	COG1959@1|root,COG1959@2|Bacteria,1VA5B@1239|Firmicutes,24JMN@186801|Clostridia,2N7M0@216572|Oscillospiraceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NHEHCBFB_01713	1519439.JPJG01000022_gene561	2.13e-80	256.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,2N71Y@216572|Oscillospiraceae	186801|Clostridia	I	Rubredoxin	bcd2	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha,Rubredoxin
NHEHCBFB_01714	748224.HMPREF9436_03237	0.0	1645.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,3WGZ6@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN
NHEHCBFB_01715	748224.HMPREF9436_03236	7.42e-256	701.0	COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,249AN@186801|Clostridia	186801|Clostridia	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
NHEHCBFB_01716	657322.FPR_04310	3.31e-68	206.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3WPY6@541000|Ruminococcaceae	186801|Clostridia	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NHEHCBFB_01717	352165.HMPREF7215_2727	1.17e-104	307.0	2DBJS@1|root,2Z9NF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
NHEHCBFB_01718	748224.HMPREF9436_03234	7.61e-254	699.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5,Lactamase_B
NHEHCBFB_01719	411490.ANACAC_03793	4.66e-14	67.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia	186801|Clostridia	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NHEHCBFB_01720	742740.HMPREF9474_03666	6.33e-43	145.0	COG1959@1|root,COG1959@2|Bacteria,1V9YG@1239|Firmicutes,24JFX@186801|Clostridia,220EE@1506553|Lachnoclostridium	186801|Clostridia	K	Winged helix-turn-helix transcription repressor, HrcA DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NHEHCBFB_01721	718252.FP2_23540	2.28e-77	232.0	COG0607@1|root,COG0607@2|Bacteria,1U0PW@1239|Firmicutes,24RKU@186801|Clostridia,3WKRD@541000|Ruminococcaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
NHEHCBFB_01722	748224.HMPREF9436_03231	5.58e-19	83.2	COG1528@1|root,COG1528@2|Bacteria,1V1BJ@1239|Firmicutes,24FUF@186801|Clostridia,3WICW@541000|Ruminococcaceae	186801|Clostridia	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
NHEHCBFB_01723	657322.FPR_04340	6.95e-111	319.0	COG1528@1|root,COG1528@2|Bacteria,1V1BJ@1239|Firmicutes,24FUF@186801|Clostridia,3WICW@541000|Ruminococcaceae	186801|Clostridia	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
NHEHCBFB_01724	411483.FAEPRAA2165_00523	1.56e-93	273.0	COG2337@1|root,COG2337@2|Bacteria,1TTJP@1239|Firmicutes,25MHP@186801|Clostridia,3WQFT@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
NHEHCBFB_01725	411483.FAEPRAA2165_00522	9.06e-46	147.0	2CBNB@1|root,32UW5@2|Bacteria,1VCKT@1239|Firmicutes,24N2B@186801|Clostridia,3WPSB@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NHEHCBFB_01726	1121333.JMLH01000033_gene2892	1.92e-182	573.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,3VNX4@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
NHEHCBFB_01727	1280698.AUJS01000017_gene1793	0.0	1669.0	COG1669@1|root,COG1669@2|Bacteria,1UKI0@1239|Firmicutes,25FXI@186801|Clostridia	186801|Clostridia	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4316,YodL
NHEHCBFB_01729	1121115.AXVN01000083_gene2477	1.19e-07	50.8	2C0GW@1|root,33C02@2|Bacteria,1VQ7E@1239|Firmicutes,24XF2@186801|Clostridia,3Y224@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01730	457412.RSAG_00580	5.69e-262	720.0	COG0791@1|root,COG0791@2|Bacteria,1UKHZ@1239|Firmicutes,25FXH@186801|Clostridia,3WHIZ@541000|Ruminococcaceae	186801|Clostridia	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
NHEHCBFB_01731	1121115.AXVN01000083_gene2475	3.4e-43	140.0	COG3655@1|root,COG3655@2|Bacteria,1UVUY@1239|Firmicutes,25M4Q@186801|Clostridia,3Y275@572511|Blautia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
NHEHCBFB_01732	1121115.AXVN01000083_gene2474	5.69e-171	476.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3XZCU@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K18349	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_01733	457412.RSAG_00577	5.83e-251	689.0	COG5002@1|root,COG5002@2|Bacteria,1TPB6@1239|Firmicutes,24AV5@186801|Clostridia,3WH3Q@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase- DNA gyrase B	-	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
NHEHCBFB_01734	457412.RSAG_00576	1.09e-189	528.0	COG0845@1|root,COG0845@2|Bacteria,1U20J@1239|Firmicutes,24A0Q@186801|Clostridia	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01735	1121115.AXVN01000083_gene2471	3.39e-165	462.0	COG1136@1|root,COG1136@2|Bacteria,1V0UF@1239|Firmicutes,24E8G@186801|Clostridia,3Y1CN@572511|Blautia	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NHEHCBFB_01736	457412.RSAG_00574	3.63e-270	741.0	COG0577@1|root,COG0577@2|Bacteria,1TS8R@1239|Firmicutes,24EBA@186801|Clostridia	186801|Clostridia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
NHEHCBFB_01737	457412.RSAG_00573	2.09e-120	343.0	28KKS@1|root,2ZA5I@2|Bacteria,1V11Y@1239|Firmicutes,24EK5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01738	411474.COPEUT_01887	2.22e-231	636.0	COG1686@1|root,COG1686@2|Bacteria,1UYI0@1239|Firmicutes,24A51@186801|Clostridia	186801|Clostridia	M	serine-type D-Ala-D-Ala carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S11
NHEHCBFB_01739	411474.COPEUT_01888	1.9e-90	265.0	COG0745@1|root,COG0745@2|Bacteria,1VCS1@1239|Firmicutes,24PPD@186801|Clostridia	186801|Clostridia	KT	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
NHEHCBFB_01740	1200567.JNKD01000019_gene1407	1.37e-15	77.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,1RQQA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM Transposase, IS204 IS1001 IS1096 IS1165	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
NHEHCBFB_01742	457412.RSAG_00913	4.19e-94	279.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,24GD7@186801|Clostridia,3WK2W@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
NHEHCBFB_01743	411461.DORFOR_02023	1.49e-83	249.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,24HPW@186801|Clostridia,27WAJ@189330|Dorea	186801|Clostridia	S	Uncharacterized BCR, YaiI/YqxD family COG1671	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
NHEHCBFB_01744	1232447.BAHW02000027_gene2070	1.43e-22	93.6	2DP32@1|root,330AW@2|Bacteria,1VGSG@1239|Firmicutes,24Q56@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01745	1232447.BAHW02000027_gene2069	1.62e-309	846.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,267V4@186813|unclassified Clostridiales	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NHEHCBFB_01746	411469.EUBHAL_00459	3.87e-67	204.0	296J0@1|root,2ZTUJ@2|Bacteria,1V3IP@1239|Firmicutes,24H9K@186801|Clostridia,25X10@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
NHEHCBFB_01747	1121333.JMLH01000050_gene627	4.64e-83	246.0	COG2315@1|root,COG2315@2|Bacteria,1V4K7@1239|Firmicutes,3VQU7@526524|Erysipelotrichia	526524|Erysipelotrichia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
NHEHCBFB_01748	1121333.JMLH01000050_gene628	2.02e-39	130.0	COG1476@1|root,COG1476@2|Bacteria,1VCCB@1239|Firmicutes	1239|Firmicutes	K	transcriptional regulators	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NHEHCBFB_01749	1121333.JMLH01000050_gene629	4.16e-178	495.0	COG1974@1|root,COG1974@2|Bacteria,1UJ92@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
NHEHCBFB_01750	1232447.BAHW02000027_gene2063	5.06e-308	839.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,26AAN@186813|unclassified Clostridiales	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
NHEHCBFB_01751	457412.RSAG_04562	7.94e-41	134.0	COG1974@1|root,COG1974@2|Bacteria,1VDZS@1239|Firmicutes,25E0Q@186801|Clostridia	186801|Clostridia	L	LexA DNA binding domain	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind
NHEHCBFB_01752	1121333.JMLH01000050_gene632	3.9e-54	169.0	2E5HW@1|root,33098@2|Bacteria,1VFFD@1239|Firmicutes,3VS8G@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01753	1232447.BAHW02000027_gene2060	2.66e-132	375.0	28KSD@1|root,2ZA9R@2|Bacteria,1UZZ4@1239|Firmicutes,249ZS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01754	1121333.JMLH01000050_gene634	7.87e-88	257.0	28PBY@1|root,2ZC4G@2|Bacteria,1V2G3@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01755	457412.RSAG_03429	4.95e-37	124.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,3WKG3@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rd	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
NHEHCBFB_01756	457412.RSAG_03428	7.66e-96	279.0	COG2703@1|root,COG2703@2|Bacteria,1VAI0@1239|Firmicutes,24MQU@186801|Clostridia,3WKH1@541000|Ruminococcaceae	186801|Clostridia	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
NHEHCBFB_01757	411459.RUMOBE_03486	1.31e-27	101.0	2DE2W@1|root,2ZKAM@2|Bacteria,1V3EH@1239|Firmicutes,24GFD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01758	411459.RUMOBE_03487	9.76e-24	91.7	2C9RV@1|root,32WXH@2|Bacteria,1VCZ0@1239|Firmicutes,24NC4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01759	180332.JTGN01000004_gene2620	7.04e-182	540.0	COG1609@1|root,COG1879@1|root,COG1609@2|Bacteria,COG1879@2|Bacteria,1TS5P@1239|Firmicutes,24E9X@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3,Peripla_BP_4
NHEHCBFB_01760	97139.C824_03759	3.1e-127	369.0	COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,24AF7@186801|Clostridia,36GBX@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
NHEHCBFB_01761	97139.C824_03760	4.23e-150	436.0	COG1879@1|root,COG1879@2|Bacteria,1TSN1@1239|Firmicutes,249RI@186801|Clostridia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NHEHCBFB_01762	887325.HMPREF0381_2858	4.71e-225	635.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,1HVMT@1164882|Lachnoanaerobaculum	186801|Clostridia	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K02056,ko:K17204	ko02010,map02010	M00221,M00590	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.11,3.A.1.2.16	-	-	ABC_tran
NHEHCBFB_01763	887325.HMPREF0381_2857	1.68e-146	422.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,1HUGI@1164882|Lachnoanaerobaculum	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NHEHCBFB_01764	887325.HMPREF0381_2856	5.21e-244	674.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NHEHCBFB_01765	1410632.JHWW01000002_gene2166	1.57e-92	287.0	COG0673@1|root,COG0673@2|Bacteria,1TQFW@1239|Firmicutes,24BIG@186801|Clostridia,27KU6@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NHEHCBFB_01766	500635.MITSMUL_05537	7.54e-194	540.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,4H77A@909932|Negativicutes	909932|Negativicutes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
NHEHCBFB_01767	97139.C824_03757	9.72e-257	707.0	COG0673@1|root,COG0673@2|Bacteria,1TSWE@1239|Firmicutes,24DSM@186801|Clostridia,36M2M@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NHEHCBFB_01768	1280698.AUJS01000033_gene2056	3.23e-234	655.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,27WBY@189330|Dorea	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_01769	1298920.KI911353_gene4374	8.96e-188	530.0	COG1879@1|root,COG1879@2|Bacteria,1UE0M@1239|Firmicutes,24C7Y@186801|Clostridia,2246U@1506553|Lachnoclostridium	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NHEHCBFB_01770	411459.RUMOBE_00014	1.44e-251	702.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3XZ1W@572511|Blautia	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441,ko:K10542	ko02010,map02010	M00212,M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3	-	-	ABC_tran
NHEHCBFB_01771	411459.RUMOBE_00013	1.88e-183	517.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3Y07K@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NHEHCBFB_01772	1121115.AXVN01000010_gene2773	1.01e-74	224.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,3Y05X@572511|Blautia	186801|Clostridia	P	Belongs to the ArsC family	spxA	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
NHEHCBFB_01773	1121115.AXVN01000010_gene2774	1.85e-213	592.0	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01774	1121115.AXVN01000010_gene2775	2.29e-88	259.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia,3Y06A@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
NHEHCBFB_01775	1121115.AXVN01000010_gene2776	3.09e-186	520.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,3XYMF@572511|Blautia	186801|Clostridia	P	COG COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
NHEHCBFB_01776	457412.RSAG_01431	3.36e-189	527.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,3WGFX@541000|Ruminococcaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
NHEHCBFB_01777	1121115.AXVN01000010_gene2778	1.79e-192	536.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,3XYWM@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
NHEHCBFB_01778	1121115.AXVN01000010_gene2779	4.13e-178	496.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3XYGV@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
NHEHCBFB_01779	457412.RSAG_01428	6.08e-153	430.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,3WIXN@541000|Ruminococcaceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
NHEHCBFB_01780	1121115.AXVN01000010_gene2781	0.0	942.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XZMN@572511|Blautia	186801|Clostridia	T	Single Cache-like	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
NHEHCBFB_01781	457412.RSAG_01421	0.0	1655.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3WGRC@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NHEHCBFB_01782	457412.RSAG_01420	4.45e-133	377.0	COG1309@1|root,COG1309@2|Bacteria,1V73E@1239|Firmicutes,25B5N@186801|Clostridia,3WJEZ@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NHEHCBFB_01783	1121115.AXVN01000010_gene2789	6.67e-123	352.0	COG3247@1|root,COG3247@2|Bacteria,1VFKP@1239|Firmicutes,24RBX@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
NHEHCBFB_01784	457412.RSAG_01418	0.0	936.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	atsB	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
NHEHCBFB_01785	1121115.AXVN01000010_gene2791	0.0	1061.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3Y1DA@572511|Blautia	186801|Clostridia	KT	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NHEHCBFB_01786	457412.RSAG_01416	0.0	913.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3WGJF@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
NHEHCBFB_01787	1121115.AXVN01000010_gene2793	4.22e-244	671.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,3Y1DY@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
NHEHCBFB_01788	457412.RSAG_01414	0.0	976.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3WH2F@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system, ATPase component	araG_1	-	3.6.3.17	ko:K02056,ko:K10441	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
NHEHCBFB_01789	1121115.AXVN01000010_gene2795	7.39e-233	643.0	COG1172@1|root,COG1172@2|Bacteria,1TR6F@1239|Firmicutes,2484T@186801|Clostridia,3Y10U@572511|Blautia	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	ytfT	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NHEHCBFB_01790	1121115.AXVN01000010_gene2796	6.51e-226	624.0	COG1172@1|root,COG1172@2|Bacteria,1TPPT@1239|Firmicutes,248FJ@186801|Clostridia,3Y1F9@572511|Blautia	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	yjfF	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NHEHCBFB_01791	457412.RSAG_01411	1.18e-223	614.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,3WGYH@541000|Ruminococcaceae	186801|Clostridia	J	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
NHEHCBFB_01792	457412.RSAG_01410	5.51e-205	567.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,248B1@186801|Clostridia,3WGRW@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NHEHCBFB_01793	457412.RSAG_04514	5.14e-42	137.0	2CA4K@1|root,347XV@2|Bacteria,1VZ7Z@1239|Firmicutes,253MY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01794	457412.RSAG_03147	2.32e-219	608.0	COG5464@1|root,COG5464@2|Bacteria,1TYQI@1239|Firmicutes,24FIE@186801|Clostridia,3WRZY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
NHEHCBFB_01795	1121115.AXVN01000172_gene3991	1.73e-289	791.0	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,24B9Q@186801|Clostridia,3XZHR@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
NHEHCBFB_01796	1121115.AXVN01000091_gene2615	1.01e-311	848.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,24A83@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
NHEHCBFB_01797	1121115.AXVN01000091_gene2614	0.0	988.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia,3Y0NN@572511|Blautia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NHEHCBFB_01798	457412.RSAG_03133	2.39e-175	489.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,3WI78@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
NHEHCBFB_01799	1121115.AXVN01000091_gene2612	3.16e-93	272.0	2DD3J@1|root,32U0T@2|Bacteria,1VB00@1239|Firmicutes,24N49@186801|Clostridia,3Y0BV@572511|Blautia	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
NHEHCBFB_01800	457412.RSAG_03131	0.0	998.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,3WHGK@541000|Ruminococcaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
NHEHCBFB_01801	1121115.AXVN01000091_gene2610	5.72e-205	567.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,3XZ86@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
NHEHCBFB_01802	1121115.AXVN01000091_gene2609	1.36e-156	441.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,3XZAU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	GntR	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NHEHCBFB_01803	457412.RSAG_03128	0.0	938.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,3WHDF@541000|Ruminococcaceae	186801|Clostridia	EG	spore germination protein	gerA	-	-	ko:K06295,ko:K06310	-	-	-	-	ko00000	-	-	-	GerA
NHEHCBFB_01804	1121115.AXVN01000091_gene2607	0.0	1103.0	COG0814@1|root,COG0814@2|Bacteria,1V9NE@1239|Firmicutes,25FHY@186801|Clostridia,3XZUD@572511|Blautia	186801|Clostridia	E	Spore germination protein	-	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
NHEHCBFB_01805	1121115.AXVN01000091_gene2606	1.08e-52	166.0	2C5NI@1|root,33W5Y@2|Bacteria,1VWK5@1239|Firmicutes,2519Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01806	1121115.AXVN01000091_gene2605	2.61e-196	544.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,3XZR8@572511|Blautia	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
NHEHCBFB_01807	1121115.AXVN01000091_gene2604	5.7e-105	303.0	COG4506@1|root,COG4506@2|Bacteria,1V8CS@1239|Firmicutes,24JQR@186801|Clostridia,3Y0D5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
NHEHCBFB_01808	1121115.AXVN01000091_gene2603	7.73e-72	219.0	2AE00@1|root,313SJ@2|Bacteria,1V6FJ@1239|Firmicutes,24JFA@186801|Clostridia,3Y02Y@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01809	457412.RSAG_03122	0.0	969.0	COG0726@1|root,COG0726@2|Bacteria,1TWQ0@1239|Firmicutes,24BEF@186801|Clostridia,3WI2D@541000|Ruminococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
NHEHCBFB_01810	457412.RSAG_03121	0.0	915.0	COG0726@1|root,COG0726@2|Bacteria,1TWQ0@1239|Firmicutes,24BEF@186801|Clostridia,3WI2D@541000|Ruminococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
NHEHCBFB_01811	457412.RSAG_03120	5.34e-273	751.0	COG0544@1|root,COG0544@2|Bacteria,1V3TE@1239|Firmicutes,24AAA@186801|Clostridia,3WKE4@541000|Ruminococcaceae	186801|Clostridia	M	Bacterial trigger factor protein (TF) C-terminus	tig_1	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C
NHEHCBFB_01812	457412.RSAG_03119	1.38e-271	749.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24MJ1@186801|Clostridia,3WRJS@541000|Ruminococcaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,CW_binding_1,Cu_amine_oxidN1,DUF3298,Polysacc_deac_1,SH3_3
NHEHCBFB_01813	457412.RSAG_03118	0.0	1320.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NHEHCBFB_01814	457412.RSAG_03117	6.13e-48	153.0	2E6AD@1|root,330Y9@2|Bacteria,1VFG8@1239|Firmicutes,24RI6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01816	457412.RSAG_03115	5.81e-218	608.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,3WGTH@541000|Ruminococcaceae	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
NHEHCBFB_01817	457412.RSAG_03114	9.1e-235	645.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia,3WGKW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	cobW
NHEHCBFB_01818	1121115.AXVN01000076_gene2623	1.32e-138	391.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3XYSI@572511|Blautia	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
NHEHCBFB_01819	1121115.AXVN01000076_gene2622	0.0	2158.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,3XZME@572511|Blautia	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
NHEHCBFB_01820	457412.RSAG_03111	2.36e-258	712.0	COG0760@1|root,COG0760@2|Bacteria,1V1WU@1239|Firmicutes,24G3V@186801|Clostridia,3WJU9@541000|Ruminococcaceae	186801|Clostridia	O	Parvulin-like peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
NHEHCBFB_01821	1121115.AXVN01000076_gene2620	5.29e-197	545.0	COG0561@1|root,COG0561@2|Bacteria,1V1JB@1239|Firmicutes,24AY8@186801|Clostridia,3Y059@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NHEHCBFB_01822	1121115.AXVN01000076_gene2619	4.24e-290	791.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,249WK@186801|Clostridia,3XZQQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
NHEHCBFB_01823	1121115.AXVN01000076_gene2618	2.62e-121	346.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,3Y0KM@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	nfrA2	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NHEHCBFB_01824	1121115.AXVN01000076_gene2617	1.14e-95	279.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,3Y0J7@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
NHEHCBFB_01825	1121115.AXVN01000005_gene2265	1.98e-298	814.0	COG2873@1|root,COG2873@2|Bacteria,1TXZ1@1239|Firmicutes,248M7@186801|Clostridia,3Y1GM@572511|Blautia	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NHEHCBFB_01826	1121115.AXVN01000005_gene2266	2.45e-176	493.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,3XZ84@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	ssuC_2	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
NHEHCBFB_01827	457412.RSAG_03000	1.1e-179	500.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,3WIAB@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	ssuB_2	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NHEHCBFB_01828	457412.RSAG_02999	6.88e-234	645.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,3WHJD@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
NHEHCBFB_01829	457412.RSAG_02998	4.85e-136	386.0	COG1183@1|root,COG1183@2|Bacteria,1TTB7@1239|Firmicutes,24GPU@186801|Clostridia,3WH5G@541000|Ruminococcaceae	186801|Clostridia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
NHEHCBFB_01830	1121115.AXVN01000005_gene2270	5.19e-223	614.0	COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,248VU@186801|Clostridia,3XYYF@572511|Blautia	186801|Clostridia	I	Phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
NHEHCBFB_01831	1121115.AXVN01000005_gene2271	1.2e-145	410.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia,3XYMA@572511|Blautia	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
NHEHCBFB_01832	1121115.AXVN01000005_gene2272	0.0	909.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,3XYGK@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
NHEHCBFB_01833	1121115.AXVN01000005_gene2273	1.58e-264	724.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3XZ7K@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
NHEHCBFB_01834	1121115.AXVN01000005_gene2274	8e-49	155.0	2DR4V@1|root,33A63@2|Bacteria,1VKGM@1239|Firmicutes,24UDH@186801|Clostridia,3Y0TN@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
NHEHCBFB_01835	1121115.AXVN01000005_gene2275	6.24e-248	681.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,3XZ8H@572511|Blautia	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
NHEHCBFB_01836	1121115.AXVN01000005_gene2276	7.41e-176	490.0	COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,24BU5@186801|Clostridia,3XZWD@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	fnt	-	-	ko:K02598	-	-	-	-	ko00000,ko02000	1.A.16.3	-	-	Form_Nir_trans
NHEHCBFB_01837	457412.RSAG_02990	0.0	1395.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3WGKN@541000|Ruminococcaceae	186801|Clostridia	L	DNA topoisomerase III	traI	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
NHEHCBFB_01838	457412.RSAG_02989	2.85e-141	400.0	COG1207@1|root,COG1207@2|Bacteria,1UHDT@1239|Firmicutes,25Q4M@186801|Clostridia,3WH51@541000|Ruminococcaceae	186801|Clostridia	M	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
NHEHCBFB_01839	457412.RSAG_02988	5.69e-182	505.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,3WK2R@541000|Ruminococcaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
NHEHCBFB_01840	1121115.AXVN01000005_gene2280	6.9e-166	463.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,3XYM6@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
NHEHCBFB_01841	1121115.AXVN01000005_gene2281	7.85e-241	662.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
NHEHCBFB_01842	411459.RUMOBE_03555	0.0	1315.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3Y0G0@572511|Blautia	186801|Clostridia	G	Putative carbohydrate binding domain	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
NHEHCBFB_01843	1121115.AXVN01000036_gene2431	1.25e-194	545.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24A4M@186801|Clostridia,3Y0YZ@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NHEHCBFB_01844	1121115.AXVN01000041_gene2574	6.85e-139	394.0	COG2860@1|root,COG2860@2|Bacteria,1UH1K@1239|Firmicutes,24HHG@186801|Clostridia,3XYJI@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yicG	-	-	-	-	-	-	-	-	-	-	-	UPF0126
NHEHCBFB_01845	1121115.AXVN01000041_gene2581	0.0	1110.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,3XYYP@572511|Blautia	186801|Clostridia	P	COG COG0004 Ammonia permease	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
NHEHCBFB_01846	457412.RSAG_01359	0.0	1384.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae	186801|Clostridia	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
NHEHCBFB_01847	457412.RSAG_01358	0.0	939.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3WH6T@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
NHEHCBFB_01848	1121115.AXVN01000041_gene2584	2.26e-46	149.0	COG1925@1|root,COG1925@2|Bacteria,1VEJ5@1239|Firmicutes,24R2F@186801|Clostridia,3Y0M0@572511|Blautia	186801|Clostridia	G	phosphocarrier protein HPr	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NHEHCBFB_01849	457412.RSAG_01356	0.0	1063.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,3WGE8@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
NHEHCBFB_01850	457412.RSAG_01355	0.0	2979.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,3WHE2@541000|Ruminococcaceae	186801|Clostridia	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
NHEHCBFB_01851	457412.RSAG_01354	0.0	989.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,3WGBX@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
NHEHCBFB_01852	411459.RUMOBE_03487	4.45e-20	82.4	2C9RV@1|root,32WXH@2|Bacteria,1VCZ0@1239|Firmicutes,24NC4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01853	411461.DORFOR_01832	4.68e-67	207.0	COG2452@1|root,COG2452@2|Bacteria,1UZ1U@1239|Firmicutes,24F52@186801|Clostridia	186801|Clostridia	L	SMART HTH transcriptional regulator, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1,Resolvase
NHEHCBFB_01854	411461.DORFOR_01831	2.48e-275	753.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,27WYV@189330|Dorea	186801|Clostridia	L	COG COG0675 Transposase and inactivated derivatives	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
NHEHCBFB_01855	1121115.AXVN01000004_gene1962	2.07e-61	189.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24T7M@186801|Clostridia,3Y25G@572511|Blautia	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
NHEHCBFB_01856	457412.RSAG_00395	2.96e-91	267.0	COG2172@1|root,COG2172@2|Bacteria,1VAPM@1239|Firmicutes,24J9J@186801|Clostridia,3WKBK@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
NHEHCBFB_01857	1121115.AXVN01000004_gene1960	6.24e-263	725.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3Y16V@572511|Blautia	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,SHOCT
NHEHCBFB_01858	457412.RSAG_00393	9.23e-270	737.0	COG1996@1|root,COG1996@2|Bacteria,1UI9I@1239|Firmicutes,248XK@186801|Clostridia,3WHNV@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01859	1121115.AXVN01000004_gene1958	6.73e-182	508.0	COG1512@1|root,COG1512@2|Bacteria,1V2US@1239|Firmicutes,257P6@186801|Clostridia,3Y1PM@572511|Blautia	186801|Clostridia	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
NHEHCBFB_01860	457412.RSAG_00391	2.29e-178	497.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,3WJ55@541000|Ruminococcaceae	186801|Clostridia	GM	Transport permease protein	pyrL	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
NHEHCBFB_01861	1121115.AXVN01000004_gene1956	1.27e-169	474.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3XYUG@572511|Blautia	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score 9.49	rfbB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_01862	1121115.AXVN01000004_gene1955	4.21e-266	728.0	COG1835@1|root,COG1835@2|Bacteria,1U1IX@1239|Firmicutes,25J4S@186801|Clostridia,3Y0VP@572511|Blautia	186801|Clostridia	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NHEHCBFB_01863	1121115.AXVN01000004_gene1954	1.25e-268	735.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia,3Y04U@572511|Blautia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
NHEHCBFB_01864	1121115.AXVN01000004_gene1953	6.7e-271	738.0	COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,24EAP@186801|Clostridia	186801|Clostridia	M	Stealth protein CR2, conserved region 2	-	-	-	-	-	-	-	-	-	-	-	-	Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4
NHEHCBFB_01865	457412.RSAG_00386	0.0	862.0	COG1887@1|root,COG1887@2|Bacteria,1V2N4@1239|Firmicutes,24FU6@186801|Clostridia,3WR0Q@541000|Ruminococcaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
NHEHCBFB_01866	1121115.AXVN01000004_gene1951	2.94e-97	282.0	COG0615@1|root,COG0615@2|Bacteria,1V3KY@1239|Firmicutes,24HAQ@186801|Clostridia	186801|Clostridia	IM	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
NHEHCBFB_01867	457412.RSAG_00384	1.98e-301	822.0	COG1887@1|root,COG1887@2|Bacteria,1V2N4@1239|Firmicutes,24FU6@186801|Clostridia,3WR0Q@541000|Ruminococcaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
NHEHCBFB_01868	1121115.AXVN01000004_gene1949	0.0	1959.0	COG0438@1|root,COG1887@1|root,COG0438@2|Bacteria,COG1887@2|Bacteria,1TSEW@1239|Firmicutes,25KH4@186801|Clostridia,3Y05H@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
NHEHCBFB_01869	1121115.AXVN01000004_gene1948	3.37e-176	492.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,3XZ0B@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
NHEHCBFB_01870	1121115.AXVN01000004_gene1947	7.57e-61	186.0	COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes,25P5S@186801|Clostridia,3Y0IV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PRC
NHEHCBFB_01871	1121115.AXVN01000004_gene1946	4.38e-102	295.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3XZYK@572511|Blautia	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
NHEHCBFB_01872	457412.RSAG_00378	0.0	878.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
NHEHCBFB_01873	1121115.AXVN01000004_gene1944	0.0	899.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3XYZV@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
NHEHCBFB_01874	1121115.AXVN01000004_gene1943	7.3e-121	344.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia,3XZXE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
NHEHCBFB_01875	457412.RSAG_00375	4.17e-119	340.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,3WJBW@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
NHEHCBFB_01876	1121115.AXVN01000004_gene1941	3.66e-132	374.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3XZPQ@572511|Blautia	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
NHEHCBFB_01877	1121115.AXVN01000004_gene1940	1.76e-232	640.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,3Y032@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
NHEHCBFB_01879	1121115.AXVN01000004_gene1939	8.87e-162	453.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,3XZ4H@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_01880	457412.RSAG_00367	0.0	1002.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WSQQ@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NHEHCBFB_01881	457412.RSAG_00365	6.43e-153	429.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,3WGIA@541000|Ruminococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
NHEHCBFB_01882	1121115.AXVN01000004_gene1936	6.86e-177	493.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,3XZ31@572511|Blautia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
NHEHCBFB_01883	1121115.AXVN01000004_gene1935	4.9e-172	478.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia,3XYSN@572511|Blautia	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
NHEHCBFB_01884	457412.RSAG_00362	0.0	1007.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,3WH0Z@541000|Ruminococcaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	spoVB1	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
NHEHCBFB_01885	457412.RSAG_00361	0.0	2793.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,3WGW6@541000|Ruminococcaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
NHEHCBFB_01886	1121115.AXVN01000009_gene1471	0.0	1738.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia	186801|Clostridia	G	Phosphoenolpyruvate synthase pyruvate phosphate dikinase	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
NHEHCBFB_01887	1121115.AXVN01000009_gene1470	1.11e-302	825.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3XZA1@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NHEHCBFB_01888	1121115.AXVN01000009_gene1469	1.13e-224	617.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,3XZNJ@572511|Blautia	186801|Clostridia	G	COG COG2017 Galactose mutarotase and related enzymes	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
NHEHCBFB_01889	1121115.AXVN01000009_gene1468	1.2e-202	562.0	COG0646@1|root,COG0646@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3XZSY@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
NHEHCBFB_01890	1121115.AXVN01000009_gene1467	1.21e-264	726.0	COG1146@1|root,COG2006@1|root,COG1146@2|Bacteria,COG2006@2|Bacteria,1TRX2@1239|Firmicutes,249GX@186801|Clostridia,3XZST@572511|Blautia	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_10,Fer4_7
NHEHCBFB_01891	1121115.AXVN01000009_gene1466	0.0	1052.0	COG1080@1|root,COG1080@2|Bacteria,1VRHN@1239|Firmicutes,24YXY@186801|Clostridia,3XZB5@572511|Blautia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
NHEHCBFB_01892	1121115.AXVN01000009_gene1465	6.04e-249	683.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3XZJT@572511|Blautia	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
NHEHCBFB_01893	457412.RSAG_00343	0.0	1147.0	COG0687@1|root,COG1177@1|root,COG0687@2|Bacteria,COG1177@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3WHCV@541000|Ruminococcaceae	186801|Clostridia	P	Spermidine putrescine-binding periplasmic protein	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
NHEHCBFB_01894	457412.RSAG_00344	2.03e-183	511.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,3WHJ9@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
NHEHCBFB_01895	457412.RSAG_00345	7.08e-250	686.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGI6@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
NHEHCBFB_01896	1121115.AXVN01000009_gene1461	1.26e-170	478.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,3XZ3R@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	iHN637.CLJU_RS10670	BPD_transp_1
NHEHCBFB_01897	1121115.AXVN01000009_gene1460	4.66e-197	547.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,24F3Z@186801|Clostridia,3XZMZ@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
NHEHCBFB_01898	1121115.AXVN01000009_gene1459	2.04e-274	752.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XZ16@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
NHEHCBFB_01900	457412.RSAG_00349	0.0	1514.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NHEHCBFB_01901	1121115.AXVN01000009_gene1456	4.69e-236	649.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3XYNT@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NHEHCBFB_01902	1121115.AXVN01000009_gene1455	1.42e-246	677.0	COG2197@1|root,COG2197@2|Bacteria,1V1FA@1239|Firmicutes	1239|Firmicutes	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
NHEHCBFB_01903	457412.RSAG_00352	0.0	1617.0	COG5263@1|root,COG5263@2|Bacteria,1VRVT@1239|Firmicutes,24Y3A@186801|Clostridia	186801|Clostridia	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01904	457412.RSAG_00353	3.82e-276	755.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,3WGQB@541000|Ruminococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NHEHCBFB_01905	1121115.AXVN01000004_gene1926	5.71e-262	717.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,3XZDW@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
NHEHCBFB_01906	457412.RSAG_00355	0.0	1110.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3WHFZ@541000|Ruminococcaceae	186801|Clostridia	H	acetolactate synthase large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NHEHCBFB_01907	1121115.AXVN01000004_gene1928	0.0	1098.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3XYR1@572511|Blautia	186801|Clostridia	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
NHEHCBFB_01908	1121115.AXVN01000004_gene1929	4.82e-254	697.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,3XZ5D@572511|Blautia	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
NHEHCBFB_01909	1121115.AXVN01000004_gene1930	4.72e-62	190.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,3Y0GK@572511|Blautia	186801|Clostridia	U	COG COG1862 Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
NHEHCBFB_01910	1121115.AXVN01000004_gene1932	2.08e-287	783.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,3XZ2I@572511|Blautia	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
NHEHCBFB_01911	411461.DORFOR_02720	1.12e-55	174.0	2C39Y@1|root,32RBW@2|Bacteria,1V801@1239|Firmicutes,24JSG@186801|Clostridia,27WV7@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01912	411462.DORLON_01570	2.53e-91	267.0	28PX5@1|root,2ZCH7@2|Bacteria,1V32H@1239|Firmicutes,24GGF@186801|Clostridia,27WRI@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01913	411459.RUMOBE_03454	4.92e-243	666.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,3Y087@572511|Blautia	186801|Clostridia	M	COG COG3049 Penicillin V acylase and related amidases	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
NHEHCBFB_01914	411469.EUBHAL_01643	5.46e-161	451.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,25WDM@186806|Eubacteriaceae	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NHEHCBFB_01915	585394.RHOM_13755	0.0	1056.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
NHEHCBFB_01916	411463.EUBVEN_02551	0.0	875.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,25VD8@186806|Eubacteriaceae	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
NHEHCBFB_01917	411463.EUBVEN_02552	8.9e-15	69.7	28N68@1|root,2ZBB7@2|Bacteria,1UZ5P@1239|Firmicutes,24EZI@186801|Clostridia,25Y5Y@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01918	457412.RSAG_01012	1.83e-227	630.0	COG3385@1|root,COG3385@2|Bacteria,1TRKC@1239|Firmicutes,24EUB@186801|Clostridia	186801|Clostridia	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
NHEHCBFB_01919	515620.EUBELI_20658	2.03e-53	169.0	28N68@1|root,2ZBB7@2|Bacteria,1UZ5P@1239|Firmicutes,24EZI@186801|Clostridia,25Y5Y@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01920	411462.DORLON_01574	0.0	960.0	COG1502@1|root,COG1502@2|Bacteria,1TSN8@1239|Firmicutes,249G7@186801|Clostridia,27WIC@189330|Dorea	186801|Clostridia	I	COG COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
NHEHCBFB_01921	511680.BUTYVIB_02272	5.44e-155	435.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,248B6@186801|Clostridia,4C156@830|Butyrivibrio	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_01922	411469.EUBHAL_01647	9.55e-243	667.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,249HQ@186801|Clostridia,25VS1@186806|Eubacteriaceae	186801|Clostridia	T	CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NHEHCBFB_01923	411461.DORFOR_03004	1.43e-252	693.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,27WMG@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
NHEHCBFB_01924	411461.DORFOR_03005	2.1e-129	368.0	COG0558@1|root,COG0558@2|Bacteria,1V4YR@1239|Firmicutes,24FWZ@186801|Clostridia,27W1S@189330|Dorea	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
NHEHCBFB_01926	903814.ELI_2151	2.14e-299	837.0	COG2015@1|root,COG2015@2|Bacteria,1TR7Q@1239|Firmicutes,248SN@186801|Clostridia,25Y8G@186806|Eubacteriaceae	186801|Clostridia	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
NHEHCBFB_01927	1121115.AXVN01000130_gene189	2.75e-91	267.0	COG5361@1|root,COG5361@2|Bacteria,1U2H3@1239|Firmicutes,24F4F@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
NHEHCBFB_01928	1121115.AXVN01000130_gene188	4.68e-196	543.0	COG2820@1|root,COG2820@2|Bacteria,1TSEU@1239|Firmicutes,25E2U@186801|Clostridia,3XZ3Q@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
NHEHCBFB_01929	457412.RSAG_03479	1.6e-103	299.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,3WK22@541000|Ruminococcaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
NHEHCBFB_01930	1121115.AXVN01000130_gene186	5.22e-299	814.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,3XYUY@572511|Blautia	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08920	Metalloenzyme
NHEHCBFB_01931	1121115.AXVN01000130_gene185	7.39e-113	323.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3XZW2@572511|Blautia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
NHEHCBFB_01932	457412.RSAG_03476	4.04e-304	828.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3WG9G@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
NHEHCBFB_01933	1121115.AXVN01000130_gene183	3.24e-113	325.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FR6@186801|Clostridia,3Y1GQ@572511|Blautia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
NHEHCBFB_01934	457412.RSAG_03474	1.46e-301	822.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3WG9G@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	hacA	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
NHEHCBFB_01935	457412.RSAG_03473	0.0	1032.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WHR7@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase class I and II	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,HTH_3
NHEHCBFB_01936	1121115.AXVN01000088_gene4037	4.8e-139	392.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3XZX6@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
NHEHCBFB_01937	457412.RSAG_03471	1.07e-172	504.0	COG4886@1|root,COG4886@2|Bacteria,1UKIE@1239|Firmicutes,25FXV@186801|Clostridia	186801|Clostridia	S	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
NHEHCBFB_01939	1235792.C808_04003	1.32e-78	266.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,27IDT@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NHEHCBFB_01940	1235792.C808_04004	4.01e-70	241.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UCUQ@1239|Firmicutes,24FD5@186801|Clostridia,27MYJ@186928|unclassified Lachnospiraceae	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NHEHCBFB_01941	457412.RSAG_01683	0.0	2017.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WSRP@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
NHEHCBFB_01942	457412.RSAG_01684	4.85e-193	536.0	COG0395@1|root,COG0395@2|Bacteria,1TSGI@1239|Firmicutes,24BDH@186801|Clostridia,3WJKJ@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10190	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
NHEHCBFB_01943	457412.RSAG_01685	5.08e-207	573.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia,3WIYD@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport systems permease components	-	-	-	ko:K02025,ko:K10189	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	BPD_transp_1
NHEHCBFB_01944	457412.RSAG_01686	9.35e-312	849.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia,3WMKQ@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10188	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_01945	457412.RSAG_01687	9.49e-111	320.0	2BXQ3@1|root,2ZCWE@2|Bacteria,1V3E8@1239|Firmicutes,24GTI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01946	457412.RSAG_01688	2.57e-202	562.0	COG2207@1|root,COG2207@2|Bacteria,1V0IW@1239|Firmicutes,24BME@186801|Clostridia,3WM59@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NHEHCBFB_01947	457412.RSAG_01689	3.58e-209	579.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3WI0F@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
NHEHCBFB_01948	1121115.AXVN01000014_gene1194	3.15e-31	109.0	2AQUU@1|root,31G2Z@2|Bacteria,1UDXX@1239|Firmicutes,25IS7@186801|Clostridia,3Y251@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01949	457412.RSAG_01691	2.95e-282	772.0	COG0526@1|root,COG0526@2|Bacteria,1TSFN@1239|Firmicutes,24DAS@186801|Clostridia	186801|Clostridia	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
NHEHCBFB_01950	457412.RSAG_01692	7.46e-157	440.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,3WH9J@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_01951	457412.RSAG_01693	5.74e-264	724.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,3WSRQ@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NHEHCBFB_01952	457412.RSAG_01694	2.79e-253	694.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,3WH25@541000|Ruminococcaceae	186801|Clostridia	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
NHEHCBFB_01953	457412.RSAG_01696	6.48e-99	286.0	COG3543@1|root,COG3543@2|Bacteria,1VAZC@1239|Firmicutes,25DS7@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1284)	-	-	-	ko:K09706	-	-	-	-	ko00000	-	-	-	DUF1284
NHEHCBFB_01954	1121115.AXVN01000107_gene614	3.2e-203	563.0	COG0697@1|root,COG0697@2|Bacteria,1TRKD@1239|Firmicutes,248I1@186801|Clostridia,3XYIR@572511|Blautia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NHEHCBFB_01955	1121115.AXVN01000107_gene613	3.2e-131	373.0	COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,24JF7@186801|Clostridia,3Y0SC@572511|Blautia	186801|Clostridia	S	Thiamine-precursor transporter protein (ThiW)	thiW	-	-	-	-	-	-	-	-	-	-	-	ThiW
NHEHCBFB_01956	457412.RSAG_01699	2.14e-148	418.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,3WGUI@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
NHEHCBFB_01957	1121115.AXVN01000107_gene611	0.0	874.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3XZ7Z@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_01958	1121115.AXVN01000107_gene610	5.62e-316	861.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,3Y07Q@572511|Blautia	186801|Clostridia	P	Voltage gated chloride channel	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
NHEHCBFB_01959	1121115.AXVN01000107_gene609	0.0	1424.0	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,24ARZ@186801|Clostridia	186801|Clostridia	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
NHEHCBFB_01960	457412.RSAG_01913	0.0	1323.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3WGAB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk1	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
NHEHCBFB_01961	1121115.AXVN01000078_gene2832	2.08e-216	598.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,3XYZZ@572511|Blautia	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
NHEHCBFB_01962	457412.RSAG_04574	8.39e-307	839.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WGBD@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_01963	457412.RSAG_01922	3.99e-134	381.0	COG4720@1|root,COG4720@2|Bacteria,1USKD@1239|Firmicutes,24A2K@186801|Clostridia,3WKAY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
NHEHCBFB_01964	1121115.AXVN01000078_gene2826	5.64e-275	753.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3XYME@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
NHEHCBFB_01965	1121115.AXVN01000078_gene2825	0.0	1057.0	28NHG@1|root,2ZBJ9@2|Bacteria,1V1QG@1239|Firmicutes,24GQ1@186801|Clostridia,3Y0RS@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NHEHCBFB_01966	457412.RSAG_01925	4.41e-126	361.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WK21@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NHEHCBFB_01967	457412.RSAG_01927	1.79e-113	326.0	COG1418@1|root,COG1418@2|Bacteria,1V70P@1239|Firmicutes,24JTJ@186801|Clostridia,3WJN7@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HD
NHEHCBFB_01968	457412.RSAG_01928	8.74e-281	767.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_5,Lactamase_B
NHEHCBFB_01969	457412.RSAG_01929	7.89e-217	599.0	COG5464@1|root,COG5464@2|Bacteria,1TUFY@1239|Firmicutes,259KT@186801|Clostridia,3WQBQ@541000|Ruminococcaceae	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01970	1121115.AXVN01000098_gene2882	5.61e-98	285.0	2CV0R@1|root,32SWK@2|Bacteria,1VDAN@1239|Firmicutes,24K0G@186801|Clostridia	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
NHEHCBFB_01971	1121115.AXVN01000098_gene2881	1.24e-79	236.0	2DYSA@1|root,34AWR@2|Bacteria,1VZ6D@1239|Firmicutes,250AC@186801|Clostridia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
NHEHCBFB_01972	457412.RSAG_01932	8.93e-191	531.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3WH9Z@541000|Ruminococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
NHEHCBFB_01973	457412.RSAG_01933	2.32e-219	608.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,24AF9@186801|Clostridia,3WNDD@541000|Ruminococcaceae	186801|Clostridia	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
NHEHCBFB_01974	742735.HMPREF9467_00699	3e-120	352.0	COG1082@1|root,COG1082@2|Bacteria,1UXR5@1239|Firmicutes,25A81@186801|Clostridia,22358@1506553|Lachnoclostridium	186801|Clostridia	L	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NHEHCBFB_01975	1232453.BAIF02000026_gene4318	2.15e-74	228.0	COG0794@1|root,COG0794@2|Bacteria,1UYG2@1239|Firmicutes,24DJV@186801|Clostridia	186801|Clostridia	M	6-phospho 3-hexuloisomerase	-	-	5.3.1.27	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05339,R09780	RC00377	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS
NHEHCBFB_01976	742735.HMPREF9467_00697	8.7e-154	441.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,21XEX@1506553|Lachnoclostridium	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
NHEHCBFB_01977	742735.HMPREF9467_00696	9.61e-249	695.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,21XJ5@1506553|Lachnoclostridium	186801|Clostridia	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
NHEHCBFB_01978	742735.HMPREF9467_00695	2.05e-155	445.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,249ZI@186801|Clostridia,21ZW0@1506553|Lachnoclostridium	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NHEHCBFB_01979	742735.HMPREF9467_00694	1.01e-248	696.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,21XVP@1506553|Lachnoclostridium	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
NHEHCBFB_01980	483218.BACPEC_00742	6.01e-68	214.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,268XI@186813|unclassified Clostridiales	186801|Clostridia	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
NHEHCBFB_01981	742735.HMPREF9467_00692	3.44e-138	397.0	COG1737@1|root,COG1737@2|Bacteria,1V98J@1239|Firmicutes,24K08@186801|Clostridia,220NG@1506553|Lachnoclostridium	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NHEHCBFB_01982	1121115.AXVN01000098_gene2878	6.83e-296	807.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,3XZP1@572511|Blautia	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
NHEHCBFB_01983	457412.RSAG_01409	3.88e-170	478.0	2DJUM@1|root,307DY@2|Bacteria,1U1HZ@1239|Firmicutes,24V47@186801|Clostridia,3WR1D@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
NHEHCBFB_01984	457412.RSAG_01408	3.27e-295	808.0	COG4632@1|root,COG5263@1|root,COG4632@2|Bacteria,COG5263@2|Bacteria,1TR6Z@1239|Firmicutes,25B3H@186801|Clostridia,3WJIW@541000|Ruminococcaceae	186801|Clostridia	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
NHEHCBFB_01985	1121115.AXVN01000010_gene2802	7.51e-23	87.8	2CA4N@1|root,2ZQ5H@2|Bacteria,1W5T5@1239|Firmicutes,256DT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01986	457412.RSAG_01406	9.71e-317	862.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,3WGVJ@541000|Ruminococcaceae	186801|Clostridia	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
NHEHCBFB_01987	457412.RSAG_01405	0.0	911.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3WIPN@541000|Ruminococcaceae	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NHEHCBFB_01988	457412.RSAG_01404	2.3e-256	702.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WGGM@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
NHEHCBFB_01989	457412.RSAG_01403	0.0	903.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WH5M@541000|Ruminococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NHEHCBFB_01990	1121115.AXVN01000010_gene2808	7.55e-136	385.0	2EXAI@1|root,33QM6@2|Bacteria,1VU0R@1239|Firmicutes,24YTY@186801|Clostridia,3Y0G1@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01991	1121115.AXVN01000010_gene2809	2.97e-63	192.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia,3Y0DQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01992	1121115.AXVN01000037_gene3266	0.0	1484.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3XYPZ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	ybhJ	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
NHEHCBFB_01993	457412.RSAG_01390	5.46e-169	471.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,3WHF8@541000|Ruminococcaceae	186801|Clostridia	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NHEHCBFB_01994	1121115.AXVN01000037_gene3264	2.14e-257	706.0	COG1879@1|root,COG1879@2|Bacteria,1UZFA@1239|Firmicutes,249QV@186801|Clostridia,3XYTX@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	rbsB_4	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NHEHCBFB_01995	1121115.AXVN01000037_gene3263	2.9e-56	175.0	2EC1A@1|root,3360H@2|Bacteria,1VHMT@1239|Firmicutes,24S6Y@186801|Clostridia,3Y1SK@572511|Blautia	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
NHEHCBFB_01996	1121115.AXVN01000037_gene3262	7.79e-93	271.0	2BAXA@1|root,324CZ@2|Bacteria,1UQP9@1239|Firmicutes,258FM@186801|Clostridia,3Y1K7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_01997	457412.RSAG_04512	4.26e-171	478.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6A@186801|Clostridia,3WIKS@541000|Ruminococcaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
NHEHCBFB_01998	1121115.AXVN01000037_gene3260	1.25e-56	176.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3Y1RW@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
NHEHCBFB_01999	1121115.AXVN01000037_gene3259	1.94e-91	270.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,258VV@186801|Clostridia,3Y0ZV@572511|Blautia	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_B
NHEHCBFB_02000	457412.RSAG_01381	1.5e-119	342.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24JWN@186801|Clostridia,3WS23@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
NHEHCBFB_02001	1121115.AXVN01000037_gene3257	0.0	978.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3Y1A3@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
NHEHCBFB_02002	1121115.AXVN01000037_gene3256	9.39e-196	543.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3Y0ZD@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
NHEHCBFB_02003	1121115.AXVN01000037_gene3255	0.0	907.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3Y1D7@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
NHEHCBFB_02004	1121115.AXVN01000037_gene3254	4.95e-89	261.0	COG0355@1|root,COG0355@2|Bacteria,1TTR7@1239|Firmicutes,25MVC@186801|Clostridia,3Y1KM@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_DE,ATP-synt_DE_N
NHEHCBFB_02005	457412.RSAG_01375	8.68e-44	142.0	29UA8@1|root,3489I@2|Bacteria,1VZGI@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02006	457412.RSAG_01374	5.75e-147	413.0	COG0500@1|root,COG2226@2|Bacteria,1TVU2@1239|Firmicutes,24AIJ@186801|Clostridia,3WJ6T@541000|Ruminococcaceae	186801|Clostridia	Q	Methyltransferase domain protein	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
NHEHCBFB_02007	457412.RSAG_04508	3.35e-105	303.0	COG0454@1|root,COG0456@2|Bacteria,1V3IC@1239|Firmicutes,24HK5@186801|Clostridia,3WJ6B@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,Acetyltransf_7
NHEHCBFB_02008	457412.RSAG_04637	6.69e-47	150.0	2EA3V@1|root,3348U@2|Bacteria,1VFVI@1239|Firmicutes,24RVZ@186801|Clostridia,3WQVA@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02009	411459.RUMOBE_01921	4.63e-63	193.0	COG0662@1|root,COG0662@2|Bacteria,1V7HI@1239|Firmicutes,24JQZ@186801|Clostridia	186801|Clostridia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NHEHCBFB_02010	1140001.I571_02512	1.3e-48	157.0	COG1359@1|root,COG1359@2|Bacteria,1V8JS@1239|Firmicutes,4HKAP@91061|Bacilli,4B3DQ@81852|Enterococcaceae	91061|Bacilli	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
NHEHCBFB_02011	457412.RSAG_01593	3.18e-24	92.8	2C9RV@1|root,32TR5@2|Bacteria,1VDVS@1239|Firmicutes,25AYH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02012	1121333.JMLH01000050_gene625	5.17e-34	127.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,3VNWF@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NHEHCBFB_02013	1121115.AXVN01000155_gene549	9.14e-66	200.0	296J0@1|root,2ZTUJ@2|Bacteria,1V3IP@1239|Firmicutes,24H9K@186801|Clostridia	186801|Clostridia	S	Bacterial mobilization protein MobC	-	-	-	-	-	-	-	-	-	-	-	-	MobC
NHEHCBFB_02014	1121115.AXVN01000155_gene550	3.56e-183	509.0	COG1051@1|root,COG1051@2|Bacteria,1VD3G@1239|Firmicutes,25MXE@186801|Clostridia,3Y20J@572511|Blautia	186801|Clostridia	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
NHEHCBFB_02016	457412.RSAG_01590	6.51e-177	494.0	COG4377@1|root,COG4377@2|Bacteria,1V3UF@1239|Firmicutes,24JI9@186801|Clostridia,3WM1X@541000|Ruminococcaceae	186801|Clostridia	S	Putative membrane peptidase family (DUF2324)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2324
NHEHCBFB_02017	457412.RSAG_01589	3.44e-60	186.0	2C1NT@1|root,32JUU@2|Bacteria,1V7IC@1239|Firmicutes,24JFE@186801|Clostridia,3WPC1@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02018	411463.EUBVEN_01785	1.11e-37	126.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,25XDD@186806|Eubacteriaceae	186801|Clostridia	K	adenine-specific DNA methyltransferase K06223	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NHEHCBFB_02019	471875.RUMLAC_00937	5.24e-66	201.0	292IX@1|root,2ZQ2Y@2|Bacteria,1TV0U@1239|Firmicutes,258A6@186801|Clostridia,3WMAJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02020	1280698.AUJS01000020_gene1392	1.31e-22	92.0	2EJ89@1|root,33CZF@2|Bacteria,1VNWZ@1239|Firmicutes,24RJS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02021	411461.DORFOR_00416	1.71e-211	585.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,27WHM@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_02022	97139.C824_04228	2.33e-96	285.0	COG1280@1|root,COG1280@2|Bacteria,1TSNA@1239|Firmicutes,24CNE@186801|Clostridia,36JRF@31979|Clostridiaceae	186801|Clostridia	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	ko:K11249	-	-	-	-	ko00000,ko02000	2.A.76.1.4	-	-	LysE
NHEHCBFB_02023	97139.C824_05915	1.1e-11	59.3	2C9RV@1|root,32TR5@2|Bacteria,1VDVS@1239|Firmicutes,25AYH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02024	457412.RSAG_01582	1.64e-81	257.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,3WGIN@541000|Ruminococcaceae	186801|Clostridia	P	pyridine nucleotide-disulphide oxidoreductase dimerisation	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
NHEHCBFB_02025	1121115.AXVN01000048_gene1274	2.09e-70	212.0	COG2865@1|root,COG2865@2|Bacteria,1VWB8@1239|Firmicutes,2513F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02026	1121115.AXVN01000048_gene1275	0.0	1892.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3XZE8@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,SBP_bac_3
NHEHCBFB_02027	1121115.AXVN01000048_gene1276	1.32e-61	188.0	2DZI1@1|root,32VB8@2|Bacteria,1VAA5@1239|Firmicutes,24KYU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02028	1121115.AXVN01000048_gene1277	3.43e-205	568.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3XZ6G@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
NHEHCBFB_02029	1121115.AXVN01000048_gene1278	2.65e-188	525.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,3Y13H@572511|Blautia	186801|Clostridia	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
NHEHCBFB_02030	1121115.AXVN01000048_gene1279	1.23e-52	165.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia,3Y205@572511|Blautia	186801|Clostridia	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
NHEHCBFB_02031	457412.RSAG_01572	7.01e-69	208.0	COG0526@1|root,COG0526@2|Bacteria,1UG1U@1239|Firmicutes,24SF7@186801|Clostridia,3WKHR@541000|Ruminococcaceae	186801|Clostridia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NHEHCBFB_02032	457412.RSAG_01571	3.42e-41	135.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia,3WKGM@541000|Ruminococcaceae	186801|Clostridia	H	TIGRFAM thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
NHEHCBFB_02033	1121115.AXVN01000048_gene1282	5.7e-198	548.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,3Y0YS@572511|Blautia	186801|Clostridia	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
NHEHCBFB_02034	457412.RSAG_01569	9.72e-103	296.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,3WJ1M@541000|Ruminococcaceae	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
NHEHCBFB_02036	457412.RSAG_01568	0.0	1113.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3WH9N@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HisKA_7TM,Response_reg,SBP_bac_3
NHEHCBFB_02037	457412.RSAG_01567	0.0	1030.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia	186801|Clostridia	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
NHEHCBFB_02038	457412.RSAG_01566	6.5e-124	352.0	COG1443@1|root,COG1443@2|Bacteria,1V41D@1239|Firmicutes,24KU4@186801|Clostridia,3WIG7@541000|Ruminococcaceae	186801|Clostridia	I	Belongs to the Nudix hydrolase family	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
NHEHCBFB_02039	1121115.AXVN01000048_gene1293	1.65e-140	397.0	COG0560@1|root,COG0560@2|Bacteria,1TQJY@1239|Firmicutes,2493S@186801|Clostridia,3Y0XF@572511|Blautia	186801|Clostridia	E	haloacid dehalogenase-like hydrolase	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
NHEHCBFB_02040	457412.RSAG_01564	2.12e-125	357.0	COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes,24S21@186801|Clostridia,3WSDX@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NHEHCBFB_02041	1121115.AXVN01000048_gene1295	0.0	1074.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XZEC@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NHEHCBFB_02042	457412.RSAG_01562	0.0	1156.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WHGV@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NHEHCBFB_02043	1121115.AXVN01000048_gene1297	7.78e-236	649.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia,3Y16C@572511|Blautia	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
NHEHCBFB_02044	457412.RSAG_01560	2.99e-170	505.0	COG1593@1|root,COG1638@1|root,COG1593@2|Bacteria,COG1638@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3WI33@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctP
NHEHCBFB_02048	1121115.AXVN01000108_gene620	1.04e-117	338.0	COG3090@1|root,COG3090@2|Bacteria,1V6P9@1239|Firmicutes,24JKS@186801|Clostridia,3XZTR@572511|Blautia	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
NHEHCBFB_02049	556261.HMPREF0240_00965	4.69e-307	861.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,36GA4@31979|Clostridiaceae	186801|Clostridia	L	CRISPR-associated helicase Cas3	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
NHEHCBFB_02050	658086.HMPREF0994_00953	4.61e-91	268.0	296XG@1|root,2ZU65@2|Bacteria,1V420@1239|Firmicutes,24H9A@186801|Clostridia,27MMW@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
NHEHCBFB_02051	471875.RUMLAC_01189	7.77e-79	236.0	2AUVQ@1|root,31KJ2@2|Bacteria,1V93G@1239|Firmicutes,25HNQ@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02052	411474.COPEUT_02648	6.43e-136	387.0	2DBAF@1|root,2Z82V@2|Bacteria,1TPSR@1239|Firmicutes,24AI1@186801|Clostridia	186801|Clostridia	S	CRISPR-associated protein Cas5	cas5d	-	-	ko:K19119	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
NHEHCBFB_02053	1232453.BAIF02000045_gene3477	6.54e-280	781.0	28HN3@1|root,2Z7WH@2|Bacteria,1TQ7U@1239|Firmicutes,24BMY@186801|Clostridia,2687A@186813|unclassified Clostridiales	186801|Clostridia	S	CRISPR-associated protein (Cas_Csd1)	csd1	-	-	ko:K19117	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csd1
NHEHCBFB_02054	478749.BRYFOR_05707	9.33e-197	547.0	COG3649@1|root,COG3649@2|Bacteria,1TQZ8@1239|Firmicutes,248MT@186801|Clostridia	186801|Clostridia	L	CRISPR-associated protein, CT1132 family	-	-	-	ko:K19118	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas7
NHEHCBFB_02055	556261.HMPREF0240_00971	4.95e-125	359.0	COG1468@1|root,COG1468@2|Bacteria,1TT4D@1239|Firmicutes,24B93@186801|Clostridia,36H8U@31979|Clostridiaceae	186801|Clostridia	L	CRISPR-associated protein Cas4	cas4	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
NHEHCBFB_02056	556261.HMPREF0240_00972	1.5e-205	573.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia,36DVE@31979|Clostridiaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
NHEHCBFB_02057	556261.HMPREF0240_00973	4.45e-52	165.0	COG1343@1|root,COG1343@2|Bacteria,1VAV3@1239|Firmicutes,24NZP@186801|Clostridia,36KN9@31979|Clostridiaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
NHEHCBFB_02058	457412.RSAG_01551	9.62e-271	743.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,3WISY@541000|Ruminococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
NHEHCBFB_02059	411459.RUMOBE_03324	2.68e-162	459.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UUUQ@1239|Firmicutes,25KCM@186801|Clostridia,3Y1UF@572511|Blautia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_18
NHEHCBFB_02060	411459.RUMOBE_03323	3.56e-313	855.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3XZZ6@572511|Blautia	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NHEHCBFB_02061	411459.RUMOBE_03322	1.32e-272	746.0	COG2730@1|root,COG2730@2|Bacteria,1TS9M@1239|Firmicutes,24DA9@186801|Clostridia,3XZ6Z@572511|Blautia	186801|Clostridia	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
NHEHCBFB_02062	411459.RUMOBE_03321	0.0	1142.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia,3Y14Y@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_43
NHEHCBFB_02063	457412.RSAG_01549	7.76e-81	240.0	2DSCR@1|root,33FK0@2|Bacteria,1VKCD@1239|Firmicutes,24QWS@186801|Clostridia,3WM8E@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3783
NHEHCBFB_02064	411462.DORLON_02563	7.24e-207	580.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,27VJV@189330|Dorea	186801|Clostridia	G	Glycerate kinase family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
NHEHCBFB_02065	1280694.AUJQ01000014_gene1166	1.61e-201	569.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia	186801|Clostridia	EG	Gluconate	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
NHEHCBFB_02066	33035.JPJF01000001_gene2552	1.81e-117	351.0	COG3835@1|root,COG3835@2|Bacteria,1TTCF@1239|Firmicutes,24CMJ@186801|Clostridia,3Y0S2@572511|Blautia	186801|Clostridia	KT	Putative sugar diacid recognition	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	Diacid_rec,HTH_30
NHEHCBFB_02067	457412.RSAG_01547	4.41e-218	602.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,3WGJW@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_02068	457412.RSAG_01546	2.47e-166	466.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia,3WKKW@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
NHEHCBFB_02069	33035.JPJF01000045_gene1036	6.36e-31	120.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia,3Y1GE@572511|Blautia	186801|Clostridia	EG	GntP family permease	-	-	-	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	-	-	-	ko00000,ko02000	2.A.8,2.A.8.1.2,2.A.8.1.4,2.A.8.1.8	-	iHN637.CLJU_RS05690,iHN637.CLJU_RS13905	GntP_permease
NHEHCBFB_02070	33035.JPJF01000045_gene1036	8.9e-91	280.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia,3Y1GE@572511|Blautia	186801|Clostridia	EG	GntP family permease	-	-	-	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	-	-	-	ko00000,ko02000	2.A.8,2.A.8.1.2,2.A.8.1.4,2.A.8.1.8	-	iHN637.CLJU_RS05690,iHN637.CLJU_RS13905	GntP_permease
NHEHCBFB_02071	457412.RSAG_01545	0.0	1160.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3WGPR@541000|Ruminococcaceae	186801|Clostridia	EG	Belongs to the IlvD Edd family	ilvD3	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
NHEHCBFB_02072	457412.RSAG_01544	9.55e-268	731.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WI8G@541000|Ruminococcaceae	186801|Clostridia	H	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
NHEHCBFB_02073	457412.RSAG_01543	4.32e-147	414.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia,3WHMB@541000|Ruminococcaceae	186801|Clostridia	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
NHEHCBFB_02074	457412.RSAG_01536	8.57e-156	447.0	COG2207@1|root,COG2207@2|Bacteria,1TQD7@1239|Firmicutes,249SA@186801|Clostridia,3WP6K@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NHEHCBFB_02075	457412.RSAG_01535	0.0	1426.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3WH8U@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NHEHCBFB_02076	457412.RSAG_01534	0.0	869.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24977@186801|Clostridia,3WJP9@541000|Ruminococcaceae	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_02077	457412.RSAG_01533	3.45e-206	570.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WJ61@541000|Ruminococcaceae	186801|Clostridia	P	transport systems	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NHEHCBFB_02078	457412.RSAG_01532	1.13e-188	525.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3WIS9@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NHEHCBFB_02079	457412.RSAG_01531	8.33e-190	528.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V27N@1239|Firmicutes,24EUU@186801|Clostridia,3WPI2@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
NHEHCBFB_02080	457412.RSAG_01530	0.0	1063.0	COG2972@1|root,COG2972@2|Bacteria,1V4G9@1239|Firmicutes,24IA9@186801|Clostridia,3WP6J@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
NHEHCBFB_02081	457412.RSAG_01529	0.0	1437.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3WH8U@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NHEHCBFB_02082	457412.RSAG_01528	6.23e-212	585.0	COG2207@1|root,COG2207@2|Bacteria,1UYSR@1239|Firmicutes,248R9@186801|Clostridia,3WJXM@541000|Ruminococcaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
NHEHCBFB_02083	1121115.AXVN01000123_gene2863	1.83e-298	814.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3XZFW@572511|Blautia	186801|Clostridia	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
NHEHCBFB_02084	457412.RSAG_01526	0.0	1127.0	COG2972@1|root,COG2972@2|Bacteria,1UQDY@1239|Firmicutes,249HG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
NHEHCBFB_02085	457412.RSAG_01525	0.0	1003.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSFI@1239|Firmicutes,249B8@186801|Clostridia,3WH94@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
NHEHCBFB_02086	457412.RSAG_01524	4.58e-269	737.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K03406,ko:K10439	ko02010,ko02020,ko02030,map02010,map02020,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	GntR,Peripla_BP_3,Peripla_BP_4
NHEHCBFB_02087	457412.RSAG_01523	3.05e-210	582.0	COG1172@1|root,COG1172@2|Bacteria,1UVPQ@1239|Firmicutes,25MGQ@186801|Clostridia,3WPXD@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
NHEHCBFB_02088	457412.RSAG_01522	0.0	971.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3WGJM@541000|Ruminococcaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
NHEHCBFB_02089	457412.RSAG_01521	9.07e-211	584.0	COG1172@1|root,COG1172@2|Bacteria,1U0FI@1239|Firmicutes,24B5S@186801|Clostridia,3WPSA@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NHEHCBFB_02090	1121115.AXVN01000123_gene2860	7.3e-156	439.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,3XZIA@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NHEHCBFB_02091	1121115.AXVN01000104_gene854	1.6e-108	313.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,3Y07W@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
NHEHCBFB_02092	457412.RSAG_01517	4.4e-245	672.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,24B9S@186801|Clostridia,3WGXR@541000|Ruminococcaceae	186801|Clostridia	P	Extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
NHEHCBFB_02093	457412.RSAG_01516	2.56e-185	516.0	COG0555@1|root,COG0555@2|Bacteria,1TQHR@1239|Firmicutes,24ACM@186801|Clostridia,3WIAX@541000|Ruminococcaceae	186801|Clostridia	P	Sulfate ABC transporter, permease protein CysT	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
NHEHCBFB_02094	457412.RSAG_01515	2.99e-182	508.0	COG4208@1|root,COG4208@2|Bacteria,1TS3N@1239|Firmicutes,24C3X@186801|Clostridia,3WHKV@541000|Ruminococcaceae	186801|Clostridia	P	sulfate ABC transporter	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
NHEHCBFB_02095	457412.RSAG_01514	6.25e-246	676.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WSP6@541000|Ruminococcaceae	186801|Clostridia	E	ATPases associated with a variety of cellular activities	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
NHEHCBFB_02096	1121115.AXVN01000104_gene849	0.0	1124.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,3Y0UM@572511|Blautia	186801|Clostridia	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
NHEHCBFB_02097	1121115.AXVN01000104_gene848	1.26e-75	225.0	COG1146@1|root,COG1146@2|Bacteria,1VADW@1239|Firmicutes,24MQA@186801|Clostridia,3Y1XY@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9
NHEHCBFB_02098	457412.RSAG_01511	4.23e-269	736.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3WJJK@541000|Ruminococcaceae	186801|Clostridia	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
NHEHCBFB_02099	1121115.AXVN01000104_gene846	0.0	1066.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,3Y116@572511|Blautia	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
NHEHCBFB_02100	1121115.AXVN01000104_gene845	7.3e-59	181.0	2C9HP@1|root,33Z9H@2|Bacteria,1W1CU@1239|Firmicutes,25441@186801|Clostridia,3Y0HT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02101	457412.RSAG_01508	4.25e-170	478.0	COG2755@1|root,COG2755@2|Bacteria,1VDI9@1239|Firmicutes,24MZY@186801|Clostridia	186801|Clostridia	E	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,SH3_3
NHEHCBFB_02102	1121115.AXVN01000104_gene843	0.0	953.0	COG0437@1|root,COG4624@1|root,COG0437@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,3XYSR@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
NHEHCBFB_02103	457412.RSAG_01506	3.98e-256	703.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,3WIJZ@541000|Ruminococcaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
NHEHCBFB_02104	1121115.AXVN01000068_gene3404	9.69e-42	136.0	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia,3Y0J2@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02105	1121115.AXVN01000068_gene3403	2.51e-104	305.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,3XZJ9@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
NHEHCBFB_02106	1121115.AXVN01000068_gene3402	6.98e-110	317.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3XZVD@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
NHEHCBFB_02107	1121115.AXVN01000068_gene3401	1.58e-69	211.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3XZZA@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
NHEHCBFB_02108	1121115.AXVN01000068_gene3400	0.0	1286.0	COG5434@1|root,COG5434@2|Bacteria,1V8MX@1239|Firmicutes,257MV@186801|Clostridia,3Y1ZG@572511|Blautia	186801|Clostridia	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
NHEHCBFB_02109	1121115.AXVN01000068_gene3399	0.0	2515.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,3XYKN@572511|Blautia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
NHEHCBFB_02110	457412.RSAG_01499	0.0	2378.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
NHEHCBFB_02111	457412.RSAG_01498	0.0	1168.0	COG0515@1|root,COG0515@2|Bacteria,1V2ZP@1239|Firmicutes,24G58@186801|Clostridia,3WIKP@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF5050,PASTA,Pkinase,SH3_3
NHEHCBFB_02112	1121115.AXVN01000068_gene3396	6.18e-199	550.0	COG0631@1|root,COG0631@2|Bacteria,1VTG4@1239|Firmicutes,257XD@186801|Clostridia,3Y03T@572511|Blautia	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
NHEHCBFB_02113	1121115.AXVN01000068_gene3395	3.41e-297	810.0	2CF3U@1|root,33TFS@2|Bacteria,1VS98@1239|Firmicutes,24YVZ@186801|Clostridia,3XZ6U@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02114	33035.JPJF01000008_gene1192	6.68e-06	48.1	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3XZ8Q@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NHEHCBFB_02115	457412.RSAG_01494	4.73e-209	584.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	bla1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
NHEHCBFB_02116	457412.RSAG_01493	7.66e-228	629.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,3WITB@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NHEHCBFB_02117	457412.RSAG_04528	1.62e-26	97.1	298ED@1|root,2ZVJK@2|Bacteria,1W2SQ@1239|Firmicutes,2571M@186801|Clostridia	457412.RSAG_04528|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02118	1121115.AXVN01000065_gene675	4.34e-90	264.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3XZTZ@572511|Blautia	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
NHEHCBFB_02119	457412.RSAG_01491	6.62e-105	303.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,3WGPA@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
NHEHCBFB_02120	1121115.AXVN01000065_gene677	0.0	1408.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3XYNI@572511|Blautia	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
NHEHCBFB_02121	1121115.AXVN01000065_gene678	1.31e-288	788.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
NHEHCBFB_02122	457412.RSAG_01488	1.75e-117	337.0	COG1396@1|root,COG1396@2|Bacteria,1UZN9@1239|Firmicutes,24APP@186801|Clostridia,3WPRU@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_02123	1256908.HMPREF0373_01971	9.17e-37	124.0	2E5UB@1|root,330IM@2|Bacteria,1VI5J@1239|Firmicutes,24RAY@186801|Clostridia,25XIV@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
NHEHCBFB_02124	457412.RSAG_01486	1.56e-254	697.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WHJS@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NHEHCBFB_02125	1256908.HMPREF0373_01969	2.53e-31	109.0	2CHC1@1|root,343JX@2|Bacteria,1VZRM@1239|Firmicutes,2545Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02126	742723.HMPREF9477_01326	1.05e-152	429.0	COG0358@1|root,COG0358@2|Bacteria,1UZ28@1239|Firmicutes,248N2@186801|Clostridia,27PAG@186928|unclassified Lachnospiraceae	186801|Clostridia	L	CHC2 zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
NHEHCBFB_02127	1256908.HMPREF0373_01966	0.0	874.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,25VCP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	VirE
NHEHCBFB_02128	1256908.HMPREF0373_01965	1.47e-44	145.0	2DQEK@1|root,32UNY@2|Bacteria,1VCGS@1239|Firmicutes,24MR4@186801|Clostridia,25YZW@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348
NHEHCBFB_02129	478749.BRYFOR_09071	4.5e-110	316.0	COG3727@1|root,COG3727@2|Bacteria,1V3S8@1239|Firmicutes,24MYE@186801|Clostridia	186801|Clostridia	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
NHEHCBFB_02130	478749.BRYFOR_09070	0.0	922.0	COG3066@1|root,COG3066@2|Bacteria,1TS3J@1239|Firmicutes,249BA@186801|Clostridia	186801|Clostridia	L	DNA mismatch repair	-	-	-	-	-	-	-	-	-	-	-	-	MutH
NHEHCBFB_02131	1216932.CM240_0840	1.14e-79	259.0	28IUV@1|root,2Z8TI@2|Bacteria,1TSS1@1239|Firmicutes,24ESU@186801|Clostridia,36IE9@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02132	478749.BRYFOR_09068	0.0	871.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia	186801|Clostridia	H	Psort location Cytoplasmic, score	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
NHEHCBFB_02133	397287.C807_00260	0.0	1162.0	COG0846@1|root,COG0846@2|Bacteria,1UE4Y@1239|Firmicutes,24ADB@186801|Clostridia	186801|Clostridia	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
NHEHCBFB_02134	457412.RSAG_01475	3.25e-64	196.0	2C5R4@1|root,30J7R@2|Bacteria,1TTNT@1239|Firmicutes,24Q7C@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NHEHCBFB_02135	457412.RSAG_01474	1.31e-75	226.0	2EQJM@1|root,33I5N@2|Bacteria,1VPBW@1239|Firmicutes,24WG5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02136	457412.RSAG_01473	6.74e-78	232.0	COG5658@1|root,COG5658@2|Bacteria,1VFT9@1239|Firmicutes	1239|Firmicutes	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
NHEHCBFB_02137	1121115.AXVN01000065_gene680	1.07e-35	121.0	2CHQ1@1|root,3240C@2|Bacteria,1UQE2@1239|Firmicutes,25855@186801|Clostridia,3Y1Z3@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02138	411489.CLOL250_01660	1.7e-66	202.0	295RU@1|root,30FMW@2|Bacteria,1UE97@1239|Firmicutes,25J4D@186801|Clostridia,36T0W@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
NHEHCBFB_02139	1121115.AXVN01000065_gene682	1.71e-212	588.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,3Y0WW@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_02141	1121115.AXVN01000065_gene684	2.13e-151	426.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24E4Z@186801|Clostridia,3XZ3K@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yuaJ	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
NHEHCBFB_02142	457412.RSAG_01468	5.08e-112	321.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,3WJKY@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score 8.96	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
NHEHCBFB_02143	1121115.AXVN01000065_gene686	5.59e-78	232.0	COG0239@1|root,COG0239@2|Bacteria,1TTU1@1239|Firmicutes,259CY@186801|Clostridia,3Y0J4@572511|Blautia	186801|Clostridia	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
NHEHCBFB_02144	457412.RSAG_01466	2.01e-83	254.0	28M41@1|root,2ZAI3@2|Bacteria,1UZMW@1239|Firmicutes,24ANU@186801|Clostridia,3WHAM@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria C-term(DUF2220)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220
NHEHCBFB_02145	457412.RSAG_01465	1.19e-206	573.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,3WGDH@541000|Ruminococcaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
NHEHCBFB_02146	457412.RSAG_01464	3.59e-147	414.0	2BC4V@1|root,325PN@2|Bacteria,1URQ2@1239|Firmicutes,24ZYA@186801|Clostridia,3WQB6@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
NHEHCBFB_02147	457412.RSAG_01463	2.16e-37	140.0	28I9Q@1|root,2Z8CD@2|Bacteria,1TQ4H@1239|Firmicutes,24B8Q@186801|Clostridia,3WREU@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02149	1121115.AXVN01000069_gene2315	1.16e-118	339.0	COG1595@1|root,COG1595@2|Bacteria,1TPJJ@1239|Firmicutes,24JUX@186801|Clostridia,3Y0D0@572511|Blautia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NHEHCBFB_02150	1121115.AXVN01000069_gene2316	1.24e-148	419.0	29XH4@1|root,30J7T@2|Bacteria,1UVPT@1239|Firmicutes,2503Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02151	1121115.AXVN01000069_gene2317	2.85e-194	540.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia,3XZ72@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NHEHCBFB_02152	1121115.AXVN01000069_gene2318	1.11e-298	816.0	COG1757@1|root,COG1757@2|Bacteria,1TQPI@1239|Firmicutes,2495U@186801|Clostridia,3XZ6V@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	mleN_2	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
NHEHCBFB_02153	457412.RSAG_01455	1.28e-139	395.0	COG0789@1|root,COG0789@2|Bacteria,1V53F@1239|Firmicutes,24IQ8@186801|Clostridia,3WKBG@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NHEHCBFB_02154	1121115.AXVN01000069_gene2320	1.23e-64	197.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,3Y0P1@572511|Blautia	186801|Clostridia	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
NHEHCBFB_02155	1123313.ATUT01000008_gene1808	2.75e-68	207.0	2BW9N@1|root,32QZ7@2|Bacteria,1V8SR@1239|Firmicutes,3VTHU@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02156	457412.RSAG_01453	2.69e-91	268.0	2DM5I@1|root,31T37@2|Bacteria,1V6J6@1239|Firmicutes,24K9S@186801|Clostridia,3WJPG@541000|Ruminococcaceae	186801|Clostridia	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
NHEHCBFB_02157	457412.RSAG_01452	4.17e-313	855.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGER@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_02158	1121115.AXVN01000120_gene2843	1.4e-104	302.0	COG1633@1|root,COG1633@2|Bacteria,1V72Y@1239|Firmicutes,24JY4@186801|Clostridia,3Y12U@572511|Blautia	186801|Clostridia	S	Coat F domain	-	-	-	-	-	-	-	-	-	-	-	-	Coat_F,Rubrerythrin
NHEHCBFB_02159	457412.RSAG_01511	2.52e-20	90.1	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3WJJK@541000|Ruminococcaceae	186801|Clostridia	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
NHEHCBFB_02160	457421.CBFG_01818	1.89e-151	435.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NHEHCBFB_02161	742765.HMPREF9457_02930	4.52e-233	648.0	COG1653@1|root,COG1653@2|Bacteria,1UVGF@1239|Firmicutes,25MFW@186801|Clostridia,27WU0@189330|Dorea	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NHEHCBFB_02162	742765.HMPREF9457_02931	1.38e-169	478.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NHEHCBFB_02163	742765.HMPREF9457_02932	1.6e-155	441.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NHEHCBFB_02164	476272.RUMHYD_02199	4.88e-263	731.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3XYR0@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
NHEHCBFB_02165	537007.BLAHAN_04440	2.5e-240	670.0	2CBQ9@1|root,2Z7UY@2|Bacteria,1V0C0@1239|Firmicutes,24EZN@186801|Clostridia,3XZGE@572511|Blautia	186801|Clostridia	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
NHEHCBFB_02168	457412.RSAG_01450	1.46e-24	102.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3WGUV@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
NHEHCBFB_02169	457412.RSAG_01449	2.12e-309	845.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_02170	457412.RSAG_01448	0.0	1418.0	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,24ARZ@186801|Clostridia,3WH88@541000|Ruminococcaceae	186801|Clostridia	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
NHEHCBFB_02171	457412.RSAG_01447	1.23e-296	808.0	COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,248GV@186801|Clostridia,3WN9Q@541000|Ruminococcaceae	186801|Clostridia	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
NHEHCBFB_02172	1121115.AXVN01000010_gene2761	1.77e-62	191.0	COG0831@1|root,COG0831@2|Bacteria,1V7GU@1239|Firmicutes,24MN2@186801|Clostridia	186801|Clostridia	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
NHEHCBFB_02173	1121115.AXVN01000010_gene2762	3.91e-82	243.0	COG0832@1|root,COG0832@2|Bacteria,1VAIA@1239|Firmicutes,24N65@186801|Clostridia	186801|Clostridia	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
NHEHCBFB_02174	457412.RSAG_01445	0.0	1150.0	COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,24D62@186801|Clostridia,3WGSE@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
NHEHCBFB_02176	1121115.AXVN01000010_gene2764	3.75e-119	340.0	2DC0F@1|root,2ZC7C@2|Bacteria,1UPV2@1239|Firmicutes,25HPJ@186801|Clostridia	186801|Clostridia	S	AmiS/UreI family transporter	-	-	-	ko:K03191	ko05120,map05120	-	-	-	ko00000,ko00001,ko02000	1.A.29.1.3,1.A.29.1.4,1.A.29.1.5	-	-	AmiS_UreI
NHEHCBFB_02177	1121115.AXVN01000010_gene2765	3.82e-114	327.0	COG2371@1|root,COG2371@2|Bacteria,1V7SB@1239|Firmicutes,25DT7@186801|Clostridia	186801|Clostridia	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
NHEHCBFB_02178	1121115.AXVN01000010_gene2766	5.23e-161	451.0	COG0830@1|root,COG0830@2|Bacteria,1V2H0@1239|Firmicutes,24ETM@186801|Clostridia	186801|Clostridia	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
NHEHCBFB_02179	1121115.AXVN01000010_gene2767	3.88e-140	396.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,3XZ4U@572511|Blautia	186801|Clostridia	KO	UreA amidohydrolase (urease) regulatory and maturation protein UreG	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
NHEHCBFB_02180	1121115.AXVN01000010_gene2768	8.03e-198	549.0	COG0829@1|root,COG0829@2|Bacteria,1TVM2@1239|Firmicutes,24D1J@186801|Clostridia	186801|Clostridia	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
NHEHCBFB_02181	1280698.AUJS01000036_gene57	1.61e-103	304.0	COG1476@1|root,COG1476@2|Bacteria,1UUSK@1239|Firmicutes,247YW@186801|Clostridia,27VTS@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Zn_ribbon_2
NHEHCBFB_02182	457412.RSAG_01324	7.76e-55	182.0	COG0675@1|root,COG0675@2|Bacteria,1TQAH@1239|Firmicutes,24EGY@186801|Clostridia	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
NHEHCBFB_02183	1280698.AUJS01000004_gene2875	2.39e-30	113.0	COG2207@1|root,COG2207@2|Bacteria,1TXIY@1239|Firmicutes,248D1@186801|Clostridia,27WE6@189330|Dorea	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
NHEHCBFB_02184	1121115.AXVN01000004_gene1982	5.95e-202	559.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,3Y0BE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
NHEHCBFB_02185	457412.RSAG_00413	0.0	1199.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,3WHK3@541000|Ruminococcaceae	186801|Clostridia	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
NHEHCBFB_02186	1121115.AXVN01000004_gene1980	0.0	1117.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XYGZ@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NHEHCBFB_02187	1121115.AXVN01000004_gene1979	0.0	1078.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XYTP@572511|Blautia	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NHEHCBFB_02188	1121115.AXVN01000004_gene1978	9.69e-317	862.0	COG1775@1|root,COG1775@2|Bacteria,1TS7H@1239|Firmicutes,2493U@186801|Clostridia,3Y0V9@572511|Blautia	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
NHEHCBFB_02189	1121115.AXVN01000004_gene1977	0.0	1103.0	COG1775@1|root,COG1924@1|root,COG1775@2|Bacteria,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,3Y04S@572511|Blautia	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	hgdC_1	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,HGD-D
NHEHCBFB_02190	1121115.AXVN01000004_gene1976	0.0	900.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NHEHCBFB_02191	1121115.AXVN01000004_gene1975	8.8e-210	580.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,3XZ0R@572511|Blautia	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NHEHCBFB_02192	1121115.AXVN01000004_gene1974	0.0	1185.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,3XZB2@572511|Blautia	186801|Clostridia	GT	Psort location CytoplasmicMembrane, score 10.00	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
NHEHCBFB_02193	1121115.AXVN01000004_gene1973	4.05e-53	167.0	COG1925@1|root,COG1925@2|Bacteria,1VE7N@1239|Firmicutes,24Q2D@186801|Clostridia,3Y0JB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	ptsH	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NHEHCBFB_02194	1121115.AXVN01000004_gene1972	8.91e-166	464.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia,3XYWN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
NHEHCBFB_02195	457412.RSAG_00403	6.96e-263	721.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,3WH9B@541000|Ruminococcaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
NHEHCBFB_02196	1121115.AXVN01000004_gene1969	0.0	1838.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,3XZKX@572511|Blautia	186801|Clostridia	L	Psort location	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
NHEHCBFB_02197	1121115.AXVN01000004_gene1968	6.78e-128	363.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,3Y04A@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
NHEHCBFB_02198	1121115.AXVN01000004_gene1967	1.39e-96	281.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,3Y024@572511|Blautia	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
NHEHCBFB_02199	457412.RSAG_00397	1.24e-145	410.0	COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,249KF@186801|Clostridia,3WJ44@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial transferase hexapeptide repeat protein	-	-	2.3.1.18,2.3.1.79	ko:K00633,ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
NHEHCBFB_02200	457412.RSAG_00180	1.2e-264	723.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia,3WH61@541000|Ruminococcaceae	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
NHEHCBFB_02201	457412.RSAG_00179	6.29e-196	545.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia,3WJ77@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
NHEHCBFB_02202	457412.RSAG_00178	2.6e-201	558.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WGRJ@541000|Ruminococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
NHEHCBFB_02203	1121115.AXVN01000032_gene385	0.0	1663.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3XYXU@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
NHEHCBFB_02204	1121115.AXVN01000032_gene386	2.54e-246	678.0	COG0457@1|root,COG0457@2|Bacteria,1UZDE@1239|Firmicutes,2491Z@186801|Clostridia,3XZZR@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,TPR_16,TPR_19,TPR_8,zinc_ribbon_2
NHEHCBFB_02205	457412.RSAG_00175	2.89e-105	304.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,3WIDB@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
NHEHCBFB_02206	1121115.AXVN01000032_gene388	7.11e-132	374.0	COG5423@1|root,COG5423@2|Bacteria,1V5IN@1239|Firmicutes,24JW6@186801|Clostridia,3XZUH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NHEHCBFB_02207	1121115.AXVN01000032_gene389	2.8e-63	193.0	2DVZX@1|root,33XWD@2|Bacteria,1U4E1@1239|Firmicutes,24VHN@186801|Clostridia,3Y0V7@572511|Blautia	186801|Clostridia	S	COG NOG13846 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	YabP
NHEHCBFB_02208	457412.RSAG_00172	1.07e-285	780.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia,3WJNK@541000|Ruminococcaceae	186801|Clostridia	S	sporulation protein	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
NHEHCBFB_02209	1121115.AXVN01000032_gene391	4.1e-227	627.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,3XYTC@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
NHEHCBFB_02210	457412.RSAG_00169	5.79e-112	322.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,3WIDY@541000|Ruminococcaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
NHEHCBFB_02211	457412.RSAG_00167	4.99e-191	531.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,3WGZ7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
NHEHCBFB_02212	1121115.AXVN01000032_gene394	2.05e-42	139.0	COG4224@1|root,COG4224@2|Bacteria,1TUAX@1239|Firmicutes,24QS9@186801|Clostridia,3Y0QD@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
NHEHCBFB_02213	1121115.AXVN01000032_gene395	5e-130	369.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,3XZW4@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
NHEHCBFB_02214	457412.RSAG_00164	4.64e-294	803.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,3WH60@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
NHEHCBFB_02215	1121115.AXVN01000032_gene397	0.0	955.0	2DUK2@1|root,33R10@2|Bacteria,1VR47@1239|Firmicutes,24Z5G@186801|Clostridia,3Y0TJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02216	1121115.AXVN01000032_gene398	2.89e-222	612.0	COG2866@1|root,COG2866@2|Bacteria,1UEH5@1239|Firmicutes,25JE5@186801|Clostridia,3Y01R@572511|Blautia	186801|Clostridia	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
NHEHCBFB_02217	457412.RSAG_00161	0.0	927.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,3WGSQ@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
NHEHCBFB_02218	457412.RSAG_00160	6.4e-315	858.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_02219	457412.RSAG_00159	1.94e-66	202.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,3WJZ3@541000|Ruminococcaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NHEHCBFB_02220	1121115.AXVN01000032_gene402	0.0	1643.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3XZ6B@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
NHEHCBFB_02221	622312.ROSEINA2194_00561	4.39e-72	224.0	COG1073@1|root,COG1073@2|Bacteria,1TTB0@1239|Firmicutes,24ATA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	BAAT_C
NHEHCBFB_02222	1121115.AXVN01000034_gene3867	6.7e-171	479.0	COG3315@1|root,COG3315@2|Bacteria,1UPJI@1239|Firmicutes,24BUU@186801|Clostridia,3Y152@572511|Blautia	186801|Clostridia	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
NHEHCBFB_02223	1121115.AXVN01000034_gene3866	5.93e-191	529.0	COG0596@1|root,COG0596@2|Bacteria,1TSU3@1239|Firmicutes,24DYW@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02224	1121115.AXVN01000034_gene3865	4.36e-156	437.0	COG0500@1|root,COG2226@2|Bacteria,1UVT3@1239|Firmicutes,25B9E@186801|Clostridia,3Y2DZ@572511|Blautia	186801|Clostridia	Q	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
NHEHCBFB_02226	1121115.AXVN01000034_gene3864	0.0	1083.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3XYMY@572511|Blautia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_5,Glycos_transf_1
NHEHCBFB_02227	1121115.AXVN01000034_gene3863	9.52e-63	195.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia	186801|Clostridia	F	COG NOG14451 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NHEHCBFB_02228	457412.RSAG_02504	0.0	1615.0	COG2909@1|root,COG2909@2|Bacteria,1TT0M@1239|Firmicutes,24BMZ@186801|Clostridia,3WHDT@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE
NHEHCBFB_02229	457412.RSAG_02505	8.94e-56	174.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	sacC5	-	2.7.1.4,3.2.1.80	ko:K00847,ko:K03332	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R00879,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N,PfkB
NHEHCBFB_02230	457412.RSAG_02506	0.0	1025.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3WHUY@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
NHEHCBFB_02231	1121115.AXVN01000060_gene470	0.0	1092.0	COG1653@1|root,COG1653@2|Bacteria,1TS6D@1239|Firmicutes,248CI@186801|Clostridia,3XZ5C@572511|Blautia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
NHEHCBFB_02232	1121115.AXVN01000060_gene471	3.2e-209	578.0	COG0395@1|root,COG0395@2|Bacteria,1TQ9F@1239|Firmicutes,24846@186801|Clostridia,3XZ22@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NHEHCBFB_02233	457412.RSAG_02509	4.41e-219	605.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,248XU@186801|Clostridia,3WHDQ@541000|Ruminococcaceae	186801|Clostridia	P	carbohydrate ABC transporter membrane protein 1 CUT1 family	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NHEHCBFB_02234	1121115.AXVN01000060_gene474	6.15e-236	650.0	COG1609@1|root,COG1609@2|Bacteria,1TSU0@1239|Firmicutes,24C3S@186801|Clostridia,3XZBF@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NHEHCBFB_02235	518637.EUBIFOR_01478	1.46e-10	62.4	COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,3VNUI@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_02236	411459.RUMOBE_02486	1.48e-141	399.0	28NMC@1|root,2ZA4G@2|Bacteria,1UYCN@1239|Firmicutes,24ACB@186801|Clostridia,3Y0IX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02237	411459.RUMOBE_02485	0.0	1578.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3XYUA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NHEHCBFB_02238	1121115.AXVN01000016_gene3661	0.0	1852.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3XZIP@572511|Blautia	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NHEHCBFB_02239	1121115.AXVN01000016_gene3662	3.97e-284	780.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,2494S@186801|Clostridia,3XZ44@572511|Blautia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NHEHCBFB_02240	1121115.AXVN01000002_gene1436	1.07e-64	215.0	COG5492@1|root,COG5492@2|Bacteria,1UKHW@1239|Firmicutes,25FXE@186801|Clostridia	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
NHEHCBFB_02241	1121115.AXVN01000002_gene1435	9.16e-90	265.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia,3Y096@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
NHEHCBFB_02242	1121115.AXVN01000002_gene1434	6.3e-70	212.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3Y0CQ@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
NHEHCBFB_02243	457412.RSAG_00070	0.0	1156.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WG9Y@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
NHEHCBFB_02244	457412.RSAG_00069	2.41e-45	146.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24QS3@186801|Clostridia,3WKYW@541000|Ruminococcaceae	186801|Clostridia	C	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
NHEHCBFB_02245	457412.RSAG_00068	1.89e-87	257.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,3WK31@541000|Ruminococcaceae	186801|Clostridia	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
NHEHCBFB_02246	1121115.AXVN01000002_gene1430	0.0	1307.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia,3XYS4@572511|Blautia	186801|Clostridia	P	COG COG2217 Cation transport ATPase	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
NHEHCBFB_02247	1121115.AXVN01000002_gene1429	1.98e-46	152.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,3Y0EI@572511|Blautia	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02248	457412.RSAG_00065	6.61e-110	316.0	COG0735@1|root,COG0735@2|Bacteria,1V6DP@1239|Firmicutes,24K9H@186801|Clostridia,3WM1R@541000|Ruminococcaceae	186801|Clostridia	L	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
NHEHCBFB_02249	1410632.JHWW01000021_gene418	3.44e-11	58.5	2DRWB@1|root,33DDT@2|Bacteria,1VKGH@1239|Firmicutes,24VWG@186801|Clostridia,27PQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
NHEHCBFB_02250	457412.RSAG_00063	0.0	1407.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WGIX@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
NHEHCBFB_02251	457412.RSAG_00061	3.97e-43	141.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,3WKEJ@541000|Ruminococcaceae	186801|Clostridia	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NHEHCBFB_02252	457412.RSAG_00060	7.14e-39	129.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,3WKEV@541000|Ruminococcaceae	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NHEHCBFB_02253	1121115.AXVN01000002_gene1424	2.18e-59	183.0	2DMMF@1|root,32SEK@2|Bacteria,1VAB3@1239|Firmicutes,24N8S@186801|Clostridia,3Y0F2@572511|Blautia	186801|Clostridia	S	COG NOG21970 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF2325
NHEHCBFB_02254	1121115.AXVN01000002_gene1423	1.22e-245	679.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia,3XZ1Y@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
NHEHCBFB_02255	1121115.AXVN01000002_gene1422	0.0	917.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,3XYRP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
NHEHCBFB_02256	457412.RSAG_00056	5.79e-215	597.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,3WGPF@541000|Ruminococcaceae	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydE	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
NHEHCBFB_02257	1121115.AXVN01000002_gene1420	3.75e-37	126.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia,3Y0MU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02258	457412.RSAG_00054	4.03e-238	654.0	2DUPT@1|root,33RMR@2|Bacteria,1UKHV@1239|Firmicutes,25FXD@186801|Clostridia	186801|Clostridia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NHEHCBFB_02259	1121115.AXVN01000002_gene1418	3.5e-218	600.0	COG0152@1|root,COG0152@2|Bacteria,1UF8J@1239|Firmicutes,25K96@186801|Clostridia,3XZ70@572511|Blautia	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
NHEHCBFB_02260	1121115.AXVN01000002_gene1417	0.0	1008.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3XZ0V@572511|Blautia	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
NHEHCBFB_02261	457412.RSAG_00051	8.52e-83	244.0	COG5341@1|root,COG5341@2|Bacteria,1UQFQ@1239|Firmicutes,25873@186801|Clostridia,3WM3Y@541000|Ruminococcaceae	186801|Clostridia	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
NHEHCBFB_02262	457412.RSAG_00050	0.0	901.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,24829@186801|Clostridia,3WSIQ@541000|Ruminococcaceae	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
NHEHCBFB_02263	457412.RSAG_02925	0.0	1228.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia,3WHPJ@541000|Ruminococcaceae	186801|Clostridia	P	Sulfate permease family	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
NHEHCBFB_02264	457412.RSAG_02924	5.23e-107	308.0	COG5113@1|root,COG3236@2|Bacteria,1UY8T@1239|Firmicutes,2486K@186801|Clostridia,3WGS9@541000|Ruminococcaceae	186801|Clostridia	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
NHEHCBFB_02265	568816.Acin_0981	2.25e-22	98.2	2E3Y1@1|root,32N2X@2|Bacteria,1U5VZ@1239|Firmicutes,4H8M7@909932|Negativicutes	909932|Negativicutes	S	CRISPR-associated protein (Cas_Csn2)	-	-	-	ko:K19137	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csn2
NHEHCBFB_02266	1121865.OMW_01631	2.98e-25	97.1	COG3512@1|root,COG3512@2|Bacteria,1VEH4@1239|Firmicutes,4HNYR@91061|Bacilli,4B389@81852|Enterococcaceae	91061|Bacilli	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
NHEHCBFB_02267	568816.Acin_0978	0.0	1128.0	COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,4H6PU@909932|Negativicutes	909932|Negativicutes	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer	cas9	-	-	ko:K09952	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas9-BH,Cas9_PI,Cas9_REC,HNH_4
NHEHCBFB_02268	457412.RSAG_02923	0.0	1249.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,3WIIN@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
NHEHCBFB_02269	457412.RSAG_02922	1.47e-210	581.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,3WGR8@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NHEHCBFB_02270	457412.RSAG_02921	4.66e-277	758.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,3WGHH@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
NHEHCBFB_02271	457412.RSAG_02920	1.9e-203	564.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,3WHNT@541000|Ruminococcaceae	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
NHEHCBFB_02272	457412.RSAG_02919	4.46e-156	438.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,3WGK4@541000|Ruminococcaceae	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
NHEHCBFB_02273	1121115.AXVN01000049_gene1304	1.19e-255	701.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,3XYND@572511|Blautia	186801|Clostridia	QT	Psort location Cytoplasmic, score 8.87	cdaR_3	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
NHEHCBFB_02274	457412.RSAG_02917	1.06e-199	554.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,25CBM@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NHEHCBFB_02275	1121115.AXVN01000049_gene1306	3.11e-84	248.0	2E6A2@1|root,330XY@2|Bacteria,1VISZ@1239|Firmicutes,24QK3@186801|Clostridia,3Y0F4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
NHEHCBFB_02276	1121115.AXVN01000049_gene1307	0.0	1129.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,3XYVS@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	OPT
NHEHCBFB_02277	457412.RSAG_02914	0.0	1165.0	COG4548@1|root,COG4548@2|Bacteria,1TS8V@1239|Firmicutes,249FH@186801|Clostridia,3WHZQ@541000|Ruminococcaceae	186801|Clostridia	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
NHEHCBFB_02278	1121115.AXVN01000049_gene1309	7.29e-215	593.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,249C6@186801|Clostridia,3XYS0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
NHEHCBFB_02279	457412.RSAG_00641	2.4e-139	399.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,3WGED@541000|Ruminococcaceae	186801|Clostridia	OU	Psort location Cytoplasmic, score	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NHEHCBFB_02280	1123075.AUDP01000010_gene1357	2.76e-150	431.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,3WJSS@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	rbsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NHEHCBFB_02281	1123075.AUDP01000010_gene1356	6.61e-171	483.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3WP6T@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NHEHCBFB_02282	1123075.AUDP01000010_gene1355	4.14e-277	767.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3WH2F@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system, ATPase component	rbsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
NHEHCBFB_02283	411470.RUMGNA_01765	1.45e-61	192.0	COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,24MPJ@186801|Clostridia,3Y0PG@572511|Blautia	186801|Clostridia	G	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose	rbsD	-	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
NHEHCBFB_02284	1123075.AUDP01000010_gene1353	5.56e-139	402.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,249QQ@186801|Clostridia,3WJCG@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NHEHCBFB_02285	180332.JTGN01000002_gene5673	4.61e-140	406.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NHEHCBFB_02286	1121115.AXVN01000003_gene1625	2.36e-161	453.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3XYGX@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
NHEHCBFB_02287	1121115.AXVN01000003_gene1626	8.31e-310	845.0	COG1253@1|root,COG1253@2|Bacteria,1U77R@1239|Firmicutes,25CBE@186801|Clostridia,3XZ2E@572511|Blautia	186801|Clostridia	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
NHEHCBFB_02288	457412.RSAG_00644	1.2e-76	228.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,3WJE1@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
NHEHCBFB_02289	1121115.AXVN01000003_gene1628	1.44e-277	758.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3XYKK@572511|Blautia	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
NHEHCBFB_02290	457412.RSAG_00646	0.0	987.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,3WG7J@541000|Ruminococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
NHEHCBFB_02291	1121115.AXVN01000003_gene1630	6.39e-150	422.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,3XZKT@572511|Blautia	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
NHEHCBFB_02292	1121115.AXVN01000003_gene1631	0.0	1171.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3XYWT@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
NHEHCBFB_02293	1121115.AXVN01000003_gene1632	6.32e-294	801.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,3XZ3V@572511|Blautia	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
NHEHCBFB_02294	1121115.AXVN01000003_gene1633	2.43e-205	567.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,3XYHC@572511|Blautia	186801|Clostridia	O	Psort location Extracellular, score	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
NHEHCBFB_02295	457412.RSAG_04750	3.94e-30	106.0	28RQE@1|root,2ZE30@2|Bacteria,1W6E6@1239|Firmicutes,254WA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02296	1121115.AXVN01000003_gene1635	1.14e-175	489.0	COG0500@1|root,COG0500@2|Bacteria,1UKI1@1239|Firmicutes,25FXJ@186801|Clostridia	186801|Clostridia	Q	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	-	-	-	-	-	-	-	-	-	-	SAM_MT
NHEHCBFB_02297	1121115.AXVN01000003_gene1636	0.0	1003.0	COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,249HE@186801|Clostridia,3XZ8V@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
NHEHCBFB_02298	1121115.AXVN01000003_gene1638	2.76e-158	443.0	COG2315@1|root,COG3695@1|root,COG2315@2|Bacteria,COG3695@2|Bacteria,1VVT6@1239|Firmicutes,25EAU@186801|Clostridia,3Y0FV@572511|Blautia	186801|Clostridia	L	YjbR	ogt	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1,YjbR
NHEHCBFB_02299	500632.CLONEX_00644	1.83e-162	455.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,249PK@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_02300	742765.HMPREF9457_03194	1.19e-234	647.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,27W13@189330|Dorea	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NHEHCBFB_02301	1235835.C814_02689	5.59e-98	288.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WG7X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_02302	1235835.C814_02223	0.0	1463.0	COG0577@1|root,COG0577@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,3WHE4@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NHEHCBFB_02303	500632.CLONEX_00662	3.53e-150	423.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_02304	742765.HMPREF9457_03192	0.0	1482.0	COG0577@1|root,COG0577@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
NHEHCBFB_02305	742765.HMPREF9457_03191	3.55e-258	706.0	28J8P@1|root,2Z93T@2|Bacteria,1UW2C@1239|Firmicutes,24AZ0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02306	500632.CLONEX_03295	5.31e-44	143.0	COG3311@1|root,COG3311@2|Bacteria,1VBZW@1239|Firmicutes,24P8G@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NHEHCBFB_02307	1121115.AXVN01000087_gene4062	1.63e-43	141.0	2CBNR@1|root,32T16@2|Bacteria,1VA97@1239|Firmicutes,24NAW@186801|Clostridia,3Y0QV@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02308	1121115.AXVN01000087_gene4061	9.09e-61	188.0	292P2@1|root,2ZQ6W@2|Bacteria,1V4YF@1239|Firmicutes,24I6C@186801|Clostridia,3Y0PH@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
NHEHCBFB_02309	1232443.BAIA02000081_gene860	3.75e-316	861.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NHEHCBFB_02310	742765.HMPREF9457_03186	0.0	922.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia	186801|Clostridia	L	Virulence-associated protein E	-	-	-	-	-	-	-	-	-	-	-	-	VirE
NHEHCBFB_02311	1121115.AXVN01000087_gene4057	1.89e-35	120.0	2C3T4@1|root,32S28@2|Bacteria,1VB78@1239|Firmicutes,24NAY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02312	411483.FAEPRAA2165_03328	0.0	1066.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3WG90@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NHEHCBFB_02314	1235799.C818_03007	1.23e-21	86.7	2DCK0@1|root,2ZEG2@2|Bacteria,1W2D4@1239|Firmicutes,255S2@186801|Clostridia,27SV0@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02315	411463.EUBVEN_02621	3.17e-158	454.0	COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,247S2@186801|Clostridia,25VTV@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	WYL
NHEHCBFB_02319	1122993.KB898327_gene723	4.66e-22	97.8	COG1397@1|root,COG5579@1|root,COG1397@2|Bacteria,COG5579@2|Bacteria,4NTDS@976|Bacteroidetes,2G0U6@200643|Bacteroidia	976|Bacteroidetes	O	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH,DUF1810
NHEHCBFB_02320	1121115.AXVN01000053_gene1850	3.09e-154	439.0	COG0582@1|root,COG0582@2|Bacteria,1UXHI@1239|Firmicutes,25ME9@186801|Clostridia,3XZIQ@572511|Blautia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NHEHCBFB_02321	1121115.AXVN01000034_gene3878	2.68e-58	184.0	COG1846@1|root,COG1846@2|Bacteria,1V9N7@1239|Firmicutes,24NET@186801|Clostridia,3Y0N0@572511|Blautia	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NHEHCBFB_02323	411459.RUMOBE_00729	2.9e-95	278.0	COG0716@1|root,COG0716@2|Bacteria,1V72U@1239|Firmicutes,24JNK@186801|Clostridia	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5
NHEHCBFB_02324	476272.RUMHYD_01409	8.73e-126	360.0	COG2184@1|root,COG2184@2|Bacteria,1TPUZ@1239|Firmicutes,248XF@186801|Clostridia,3XZHJ@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Bro-N,Fic
NHEHCBFB_02325	658088.HMPREF0987_01039	1.44e-200	556.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,27K4T@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_26
NHEHCBFB_02326	1280694.AUJQ01000005_gene1296	2.68e-305	849.0	COG0507@1|root,COG3410@1|root,COG0507@2|Bacteria,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,24BAG@186801|Clostridia,3NIBG@46205|Pseudobutyrivibrio	186801|Clostridia	L	Uncharacterized conserved protein (DUF2075)	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	DUF2075
NHEHCBFB_02327	1121115.AXVN01000003_gene1579	3.74e-60	186.0	COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,24NYY@186801|Clostridia,3Y09V@572511|Blautia	186801|Clostridia	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
NHEHCBFB_02328	457412.RSAG_00597	1.46e-207	574.0	COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,248CX@186801|Clostridia,3WGE2@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_02329	1121115.AXVN01000003_gene1577	8.05e-106	305.0	COG0716@1|root,COG0716@2|Bacteria,1V45R@1239|Firmicutes,24HDR@186801|Clostridia,3Y09P@572511|Blautia	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
NHEHCBFB_02330	457412.RSAG_00595	8.8e-195	538.0	COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria,1TRVH@1239|Firmicutes,249JY@186801|Clostridia,3WGGH@541000|Ruminococcaceae	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
NHEHCBFB_02331	1256908.HMPREF0373_01472	1.28e-250	691.0	COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,25CD7@186801|Clostridia,25VJA@186806|Eubacteriaceae	186801|Clostridia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
NHEHCBFB_02332	1235793.C809_02170	2.78e-14	74.7	2DXV6@1|root,32V45@2|Bacteria,1VBYR@1239|Firmicutes,24P8R@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02333	397287.C807_00878	4.96e-131	382.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,27JJ4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
NHEHCBFB_02335	457412.RSAG_00878	0.0	1748.0	COG1315@1|root,COG1315@2|Bacteria,1TRQX@1239|Firmicutes,24BWZ@186801|Clostridia,3WHD4@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,SLH
NHEHCBFB_02336	457412.RSAG_00879	1.9e-176	506.0	2BHPW@1|root,32BT5@2|Bacteria,1VKP8@1239|Firmicutes,24XAG@186801|Clostridia	186801|Clostridia	S	SANT  SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02337	457412.RSAG_00880	0.0	1110.0	COG1961@1|root,COG1961@2|Bacteria,1TWK9@1239|Firmicutes,24C30@186801|Clostridia,3WHD6@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NHEHCBFB_02339	457412.RSAG_00882	2.92e-183	509.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24BWG@186801|Clostridia,3WMNU@541000|Ruminococcaceae	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
NHEHCBFB_02340	457412.RSAG_00883	0.0	928.0	COG4145@1|root,COG4145@2|Bacteria,1UJ00@1239|Firmicutes,25F28@186801|Clostridia	186801|Clostridia	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1,2.A.21.2	-	-	SSF
NHEHCBFB_02341	457412.RSAG_00884	1.63e-52	165.0	2E714@1|root,331JV@2|Bacteria,1VQIV@1239|Firmicutes,251NJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02342	457412.RSAG_00885	5.25e-201	557.0	COG1737@1|root,COG1737@2|Bacteria,1VBUB@1239|Firmicutes,24MTV@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NHEHCBFB_02343	457412.RSAG_00886	3.03e-278	760.0	COG1820@1|root,COG1820@2|Bacteria,1UK3V@1239|Firmicutes,25FIQ@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation	iadA	-	-	ko:K01305	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Amidohydro_1
NHEHCBFB_02345	457412.RSAG_00888	6.46e-170	476.0	COG0716@1|root,COG1145@1|root,COG0716@2|Bacteria,COG1145@2|Bacteria,1VSX9@1239|Firmicutes,24ZRM@186801|Clostridia,3WSJJ@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Flavodoxin_5
NHEHCBFB_02346	1121115.AXVN01000088_gene4051	9.66e-46	147.0	COG0236@1|root,COG0236@2|Bacteria,1VEX6@1239|Firmicutes,24QWP@186801|Clostridia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
NHEHCBFB_02347	1121115.AXVN01000088_gene4050	3.66e-296	807.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
NHEHCBFB_02348	1121115.AXVN01000088_gene4049	0.0	1019.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia	186801|Clostridia	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding
NHEHCBFB_02349	457412.RSAG_03462	1.64e-237	652.0	COG2755@1|root,COG2755@2|Bacteria,1VC24@1239|Firmicutes,258FA@186801|Clostridia,3WMJV@541000|Ruminococcaceae	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02350	457412.RSAG_03463	0.0	1009.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH71@541000|Ruminococcaceae	186801|Clostridia	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
NHEHCBFB_02351	1121115.AXVN01000088_gene4046	4.12e-130	380.0	2ECV2@1|root,336SH@2|Bacteria,1VFTD@1239|Firmicutes,24WJ4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02352	457412.RSAG_03465	3.69e-186	517.0	COG2720@1|root,COG2720@2|Bacteria,1V5AV@1239|Firmicutes,24XQ2@186801|Clostridia,3WJKU@541000|Ruminococcaceae	186801|Clostridia	V	Vancomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,Transglut_core
NHEHCBFB_02353	457412.RSAG_03466	1.62e-151	426.0	2EYGG@1|root,33RQD@2|Bacteria,1VRY6@1239|Firmicutes,24XIB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02354	1121115.AXVN01000088_gene4043	1.42e-190	534.0	COG5263@1|root,COG5263@2|Bacteria,1VQWH@1239|Firmicutes,24ZPP@186801|Clostridia	186801|Clostridia	S	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
NHEHCBFB_02355	457412.RSAG_03468	1.29e-150	424.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24DES@186801|Clostridia,3WS73@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
NHEHCBFB_02356	1121115.AXVN01000088_gene4040	1.66e-78	234.0	COG2198@1|root,COG2198@2|Bacteria,1TUB6@1239|Firmicutes,257TB@186801|Clostridia,3Y0UT@572511|Blautia	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
NHEHCBFB_02357	1121115.AXVN01000088_gene4039	3.08e-299	823.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3XYWG@572511|Blautia	186801|Clostridia	O	COG COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
NHEHCBFB_02358	1121115.AXVN01000088_gene4038	0.0	1056.0	COG4886@1|root,COG4886@2|Bacteria,1UKIE@1239|Firmicutes,25FXV@186801|Clostridia	186801|Clostridia	S	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
NHEHCBFB_02360	97139.C824_01641	7.02e-40	134.0	COG2929@1|root,COG2929@2|Bacteria,1VE89@1239|Firmicutes,24N45@186801|Clostridia,36TX4@31979|Clostridiaceae	186801|Clostridia	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
NHEHCBFB_02361	457412.RSAG_01705	3.61e-142	402.0	COG0637@1|root,COG0637@2|Bacteria,1V1IW@1239|Firmicutes,24FZZ@186801|Clostridia,3WRQ7@541000|Ruminococcaceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	CpXC,HAD_2
NHEHCBFB_02362	1121115.AXVN01000042_gene3038	0.0	887.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,3XYVQ@572511|Blautia	186801|Clostridia	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
NHEHCBFB_02363	1121115.AXVN01000042_gene3037	1.4e-90	265.0	2AU16@1|root,31JM9@2|Bacteria,1V6CJ@1239|Firmicutes,24JBF@186801|Clostridia,3Y05D@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02364	1121115.AXVN01000042_gene3036	0.0	1547.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3XYKC@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 9.98	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
NHEHCBFB_02365	457412.RSAG_01709	9.51e-81	239.0	COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,24J7Q@186801|Clostridia,3WJKW@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NHEHCBFB_02366	457412.RSAG_01710	1.96e-178	497.0	28NW4@1|root,32MWE@2|Bacteria,1TUAZ@1239|Firmicutes,259BP@186801|Clostridia,3WPWQ@541000|Ruminococcaceae	186801|Clostridia	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
NHEHCBFB_02367	1121115.AXVN01000042_gene3032	1.14e-314	856.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,3XYZ3@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
NHEHCBFB_02368	1121115.AXVN01000042_gene3031	1.83e-148	418.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,3XYPA@572511|Blautia	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
NHEHCBFB_02369	1121115.AXVN01000042_gene3030	4.78e-249	683.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,3XYWD@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
NHEHCBFB_02370	1121115.AXVN01000042_gene3029	1.31e-109	316.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3XZ51@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
NHEHCBFB_02371	1121115.AXVN01000042_gene3028	0.0	1358.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia,3XYTQ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
NHEHCBFB_02372	1121115.AXVN01000042_gene3027	4.05e-64	196.0	2EENY@1|root,338GS@2|Bacteria,1VJM1@1239|Firmicutes,24T09@186801|Clostridia,3Y0JX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02373	457412.RSAG_01717	3.54e-105	304.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia,3WK49@541000|Ruminococcaceae	186801|Clostridia	V	Glycopeptide antibiotics resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NHEHCBFB_02374	1121115.AXVN01000042_gene3025	6.09e-24	90.9	2DRBT@1|root,33B4Z@2|Bacteria,1VMZQ@1239|Firmicutes,24UIT@186801|Clostridia,3Y0RQ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02375	1121115.AXVN01000042_gene3024	2.7e-161	451.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,3XYW9@572511|Blautia	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
NHEHCBFB_02376	1121115.AXVN01000042_gene3023	6.23e-213	588.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,3XZ9C@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
NHEHCBFB_02377	1121115.AXVN01000042_gene3022	2.94e-192	533.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,3XZA9@572511|Blautia	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
NHEHCBFB_02378	1121115.AXVN01000042_gene3021	4.46e-226	622.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,3XZ6C@572511|Blautia	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
NHEHCBFB_02379	1121115.AXVN01000042_gene3020	9.71e-317	861.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,3XYP9@572511|Blautia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
NHEHCBFB_02380	1121115.AXVN01000042_gene3019	1.04e-41	136.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,3Y0CS@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
NHEHCBFB_02381	1121115.AXVN01000042_gene3018	7.64e-61	192.0	2DUBB@1|root,33PT0@2|Bacteria,1VSM4@1239|Firmicutes,24YVT@186801|Clostridia,3Y0NE@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02382	457412.RSAG_01726	1.51e-198	550.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia,3WI03@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NHEHCBFB_02383	1121115.AXVN01000042_gene3016	1.12e-119	341.0	2C2B5@1|root,32RA4@2|Bacteria,1V6P1@1239|Firmicutes,24N51@186801|Clostridia,3Y05S@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02384	1121115.AXVN01000042_gene3015	7.42e-75	223.0	COG0745@1|root,COG0745@2|Bacteria,1UK3F@1239|Firmicutes,25FI6@186801|Clostridia,3Y0KY@572511|Blautia	186801|Clostridia	KT	Sporulation initiation factor Spo0A C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Spo0A_C
NHEHCBFB_02385	1121115.AXVN01000042_gene3014	0.0	1360.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,3XZ94@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
NHEHCBFB_02386	1121115.AXVN01000042_gene3013	0.0	1459.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	ArabFuran-catal,CHU_C,DUF11,IgGFc_binding,LTD,NPCBM_assoc,Peptidase_M11,SprB
NHEHCBFB_02387	457412.RSAG_01731	2.36e-51	162.0	2E51P@1|root,32ZV2@2|Bacteria,1VFYG@1239|Firmicutes,24QWN@186801|Clostridia,3WKYT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02388	1121115.AXVN01000042_gene3011	3.83e-191	530.0	COG0561@1|root,COG0561@2|Bacteria,1V43V@1239|Firmicutes,24AQQ@186801|Clostridia,3XZTP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NHEHCBFB_02389	1121115.AXVN01000042_gene3010	3.18e-162	453.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia,3XZXU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NHEHCBFB_02390	457412.RSAG_01734	4.92e-136	385.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3WJIZ@541000|Ruminococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
NHEHCBFB_02391	1121115.AXVN01000042_gene3008	2.69e-46	153.0	2F1AC@1|root,33UBB@2|Bacteria,1VUR2@1239|Firmicutes,2503K@186801|Clostridia,3Y24T@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02392	457412.RSAG_01736	0.0	1137.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,3WH6G@541000|Ruminococcaceae	186801|Clostridia	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
NHEHCBFB_02393	457412.RSAG_01737	4.38e-123	350.0	COG4636@1|root,COG4636@2|Bacteria,1TT9W@1239|Firmicutes,24ANM@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NHEHCBFB_02395	1121115.AXVN01000118_gene3305	3.32e-135	383.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,249VX@186801|Clostridia,3XZYB@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
NHEHCBFB_02396	1121115.AXVN01000118_gene3306	5.22e-173	483.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,3XZ93@572511|Blautia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
NHEHCBFB_02397	457412.RSAG_01741	2.48e-106	307.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,3WJN8@541000|Ruminococcaceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
NHEHCBFB_02398	1121115.AXVN01000118_gene3308	0.0	922.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,3XZA4@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
NHEHCBFB_02399	457412.RSAG_01743	1.05e-112	323.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,3WITA@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
NHEHCBFB_02400	1121115.AXVN01000118_gene3310	1.78e-302	825.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25AGX@186801|Clostridia,3XZXG@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH_2
NHEHCBFB_02401	1121115.AXVN01000118_gene3311	6.81e-312	855.0	COG2367@1|root,COG2367@2|Bacteria,1V6K6@1239|Firmicutes,24KPP@186801|Clostridia,3Y01V@572511|Blautia	186801|Clostridia	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
NHEHCBFB_02402	1121115.AXVN01000118_gene3312	0.0	1556.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,3XYZ7@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
NHEHCBFB_02403	457412.RSAG_01747	0.0	865.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3WHC9@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartokinase family	thrA	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
NHEHCBFB_02404	1121115.AXVN01000071_gene3935	3.05e-175	489.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia,3XZMC@572511|Blautia	186801|Clostridia	S	Uncharacterised protein family UPF0066	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
NHEHCBFB_02405	1121115.AXVN01000116_gene2327	0.0	876.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	agcS_2	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NHEHCBFB_02406	457412.RSAG_01750	0.0	1338.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3WI2B@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
NHEHCBFB_02407	1121115.AXVN01000116_gene2324	0.0	1468.0	COG5427@1|root,COG5427@2|Bacteria,1UY7V@1239|Firmicutes,24BA0@186801|Clostridia,3XZJV@572511|Blautia	186801|Clostridia	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
NHEHCBFB_02408	1121115.AXVN01000206_gene3748	2.33e-203	569.0	COG3290@1|root,COG3290@2|Bacteria,1V46S@1239|Firmicutes,24KBY@186801|Clostridia,3Y1U0@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NHEHCBFB_02409	1121115.AXVN01000081_gene3055	1.98e-109	318.0	COG3279@1|root,COG3279@2|Bacteria,1VBY3@1239|Firmicutes,24GY2@186801|Clostridia	186801|Clostridia	KT	LytTr DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NHEHCBFB_02410	1121115.AXVN01000081_gene3054	1.64e-286	787.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,3XZGY@572511|Blautia	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
NHEHCBFB_02411	457412.RSAG_01752	3.94e-172	481.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,3WIER@541000|Ruminococcaceae	186801|Clostridia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
NHEHCBFB_02413	1121115.AXVN01000081_gene3052	7.61e-291	793.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,3XYS6@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
NHEHCBFB_02414	1121115.AXVN01000081_gene3051	0.0	950.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,3XYNN@572511|Blautia	186801|Clostridia	H	FGGY family of carbohydrate kinases, C-terminal domain	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
NHEHCBFB_02415	1121115.AXVN01000081_gene3050	6.15e-242	667.0	COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NHEHCBFB_02416	1121115.AXVN01000081_gene3049	2.02e-222	614.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3XZJF@572511|Blautia	186801|Clostridia	P	COG COG1172 Ribose xylose arabinose galactoside ABC-type transport systems, permease components	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NHEHCBFB_02417	1121115.AXVN01000081_gene3048	0.0	973.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3XZ1W@572511|Blautia	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
NHEHCBFB_02418	457412.RSAG_01759	2.59e-229	632.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3WNJT@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NHEHCBFB_02419	1121115.AXVN01000081_gene3046	1.67e-225	622.0	COG1879@1|root,COG1879@2|Bacteria,1TPWA@1239|Firmicutes,25PX0@186801|Clostridia,3XYI7@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NHEHCBFB_02420	1121115.AXVN01000081_gene3045	0.0	1144.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3XZ6E@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NHEHCBFB_02421	457412.RSAG_01762	0.0	1037.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3WJ5A@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
NHEHCBFB_02422	457412.RSAG_03510	2.27e-103	298.0	COG4154@1|root,COG4154@2|Bacteria,1V402@1239|Firmicutes,24FU7@186801|Clostridia,3WJ3H@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the RbsD FucU family	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
NHEHCBFB_02423	1121115.AXVN01000081_gene3042	0.0	1232.0	COG2407@1|root,COG2407@2|Bacteria,1TQ5Q@1239|Firmicutes,248V0@186801|Clostridia,3XZ8N@572511|Blautia	186801|Clostridia	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	-	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	-	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
NHEHCBFB_02424	1121115.AXVN01000086_gene4016	7.31e-212	584.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V1UE@1239|Firmicutes,24AK4@186801|Clostridia,3XZ87@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NHEHCBFB_02425	1121115.AXVN01000086_gene4015	9.18e-222	615.0	COG2096@1|root,COG3193@1|root,COG2096@2|Bacteria,COG3193@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia,3Y0ZK@572511|Blautia	186801|Clostridia	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans,Haem_degrading
NHEHCBFB_02426	1121115.AXVN01000086_gene4014	4.63e-275	752.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XZNH@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NHEHCBFB_02427	1121115.AXVN01000086_gene4013	7.36e-173	483.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia,3XZ48@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
NHEHCBFB_02428	1121115.AXVN01000086_gene4012	6.28e-118	338.0	COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,3XZUS@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	csoS1C	-	-	-	-	-	-	-	-	-	-	-	BMC
NHEHCBFB_02429	1121115.AXVN01000086_gene4011	0.0	867.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3XZ7S@572511|Blautia	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase 51 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
NHEHCBFB_02430	1121115.AXVN01000086_gene4010	9.07e-52	164.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,3Y0FT@572511|Blautia	186801|Clostridia	CQ	COG COG4576 Carbon dioxide concentrating mechanism carboxysome shell protein	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
NHEHCBFB_02431	457412.RSAG_01771	2.7e-146	412.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,3WJCD@541000|Ruminococcaceae	186801|Clostridia	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	pduL	-	2.3.1.8	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTAC
NHEHCBFB_02432	1121115.AXVN01000086_gene4008	1.22e-69	214.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NHEHCBFB_02433	1121115.AXVN01000086_gene4007	1.77e-62	191.0	COG4577@1|root,COG4577@2|Bacteria,1V9YU@1239|Firmicutes,24MUN@186801|Clostridia,3Y0DW@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NHEHCBFB_02434	1121115.AXVN01000086_gene4006	7.33e-51	161.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NHEHCBFB_02435	1121115.AXVN01000086_gene4005	2.19e-67	204.0	2CTB7@1|root,32ST1@2|Bacteria,1UPS8@1239|Firmicutes,25HN2@186801|Clostridia	186801|Clostridia	S	BMC domain	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NHEHCBFB_02436	457412.RSAG_01776	6.67e-303	825.0	COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3WS7A@541000|Ruminococcaceae	186801|Clostridia	C	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
NHEHCBFB_02437	457412.RSAG_01777	0.0	910.0	COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,3WNQC@541000|Ruminococcaceae	186801|Clostridia	C	Aldehyde dehydrogenase family	eutE	-	1.2.1.10,1.2.1.87	ko:K00132,ko:K13922	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00228,R01172,R09097	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
NHEHCBFB_02438	457412.RSAG_01778	5.57e-214	590.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3WHFE@541000|Ruminococcaceae	186801|Clostridia	G	L-fuculose phosphate aldolase	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
NHEHCBFB_02439	457412.RSAG_01779	1.15e-194	539.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,3WIZP@541000|Ruminococcaceae	186801|Clostridia	O	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NHEHCBFB_02440	457412.RSAG_01780	0.0	1699.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3WH79@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate formate lyase	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NHEHCBFB_02441	1121115.AXVN01000086_gene3999	4.49e-89	261.0	2EYFK@1|root,33RPH@2|Bacteria,1VT8U@1239|Firmicutes,24XWV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02442	1121115.AXVN01000126_gene3818	1.23e-152	438.0	COG3266@1|root,COG3266@2|Bacteria,1VS06@1239|Firmicutes,24YEU@186801|Clostridia,3Y1K6@572511|Blautia	186801|Clostridia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02443	457412.RSAG_01783	0.0	1301.0	COG4733@1|root,COG4870@1|root,COG4733@2|Bacteria,COG4870@2|Bacteria,1V2GU@1239|Firmicutes,24GPX@186801|Clostridia,3WRJP@541000|Ruminococcaceae	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,Flg_new,Peptidase_C1
NHEHCBFB_02444	1121115.AXVN01000126_gene3816	6.65e-75	223.0	COG2158@1|root,COG2158@2|Bacteria,1VFNA@1239|Firmicutes,24MYB@186801|Clostridia,3Y0C2@572511|Blautia	186801|Clostridia	S	Cysteine-rich small domain	-	-	-	ko:K07162	-	-	-	-	ko00000	-	-	-	zf-like
NHEHCBFB_02445	457412.RSAG_01785	3.45e-121	345.0	COG4917@1|root,COG4917@2|Bacteria,1V54Y@1239|Firmicutes,25DMI@186801|Clostridia	186801|Clostridia	E	Ethanolamine utilisation - propanediol utilisation	-	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
NHEHCBFB_02446	1121115.AXVN01000126_gene3814	9.74e-98	284.0	COG4810@1|root,COG4810@2|Bacteria,1V5A1@1239|Firmicutes,24IPC@186801|Clostridia,3Y03M@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
NHEHCBFB_02447	1121115.AXVN01000126_gene3813	1.73e-81	241.0	COG4810@1|root,COG4810@2|Bacteria,1V452@1239|Firmicutes,25DMT@186801|Clostridia,3Y27X@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
NHEHCBFB_02448	1121115.AXVN01000126_gene3812	1.06e-203	580.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,3XZ4Y@572511|Blautia	186801|Clostridia	M	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
NHEHCBFB_02449	1121115.AXVN01000136_gene981	3.6e-257	716.0	COG5263@1|root,COG5263@2|Bacteria,1UK2Z@1239|Firmicutes,24XW0@186801|Clostridia,3XZWP@572511|Blautia	186801|Clostridia	S	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
NHEHCBFB_02450	1121115.AXVN01000136_gene980	4.91e-240	659.0	COG1712@1|root,COG1712@2|Bacteria,1TQ4R@1239|Firmicutes,2499V@186801|Clostridia,3XYQU@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate	ddh	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C,DapB_N
NHEHCBFB_02451	1121115.AXVN01000136_gene979	1.02e-146	414.0	COG0484@1|root,COG0484@2|Bacteria,1UWW2@1239|Firmicutes,25CGC@186801|Clostridia,3XZTD@572511|Blautia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
NHEHCBFB_02452	457412.RSAG_01792	1.53e-208	575.0	2CC4I@1|root,2Z8PZ@2|Bacteria,1TQTT@1239|Firmicutes,24AJ3@186801|Clostridia,3WINQ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02453	1121115.AXVN01000136_gene977	1.2e-95	278.0	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia,3Y0F5@572511|Blautia	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02454	1121115.AXVN01000136_gene976	1.12e-125	357.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,3Y0NR@572511|Blautia	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NHEHCBFB_02455	1121115.AXVN01000136_gene975	4.08e-289	789.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,3XZRE@572511|Blautia	186801|Clostridia	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
NHEHCBFB_02456	1121115.AXVN01000119_gene3267	1.71e-144	407.0	COG1247@1|root,COG1247@2|Bacteria,1UKI4@1239|Firmicutes,25FXM@186801|Clostridia	186801|Clostridia	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NHEHCBFB_02457	1121115.AXVN01000119_gene3268	0.0	899.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia,3XZRQ@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
NHEHCBFB_02458	1121115.AXVN01000119_gene3269	2.28e-121	347.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,3Y01B@572511|Blautia	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
NHEHCBFB_02459	1121115.AXVN01000119_gene3271	0.0	1956.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1TS5R@1239|Firmicutes,24AWW@186801|Clostridia	186801|Clostridia	L	Type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
NHEHCBFB_02460	457412.RSAG_02610	6.23e-35	119.0	2BJ3C@1|root,32DC9@2|Bacteria,1V88B@1239|Firmicutes,24K97@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02461	457412.RSAG_03499	1.28e-221	616.0	COG3385@1|root,COG3385@2|Bacteria,1UZFU@1239|Firmicutes,25CHJ@186801|Clostridia,3WSD2@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NHEHCBFB_02462	457412.RSAG_03499	8.93e-23	96.7	COG3385@1|root,COG3385@2|Bacteria,1UZFU@1239|Firmicutes,25CHJ@186801|Clostridia,3WSD2@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NHEHCBFB_02463	457412.RSAG_01804	1.27e-223	616.0	COG4823@1|root,COG4823@2|Bacteria,1UY67@1239|Firmicutes,24CBG@186801|Clostridia,3WKG2@541000|Ruminococcaceae	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
NHEHCBFB_02464	411463.EUBVEN_00921	2.26e-14	65.9	2E3ZC@1|root,32YWA@2|Bacteria,1VHZW@1239|Firmicutes,24SMN@186801|Clostridia,25XQP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02465	148814.JI66_01960	1.69e-30	135.0	COG1479@1|root,COG1479@2|Bacteria,1W0EJ@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02466	411469.EUBHAL_02123	0.0	1100.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,25VPH@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NHEHCBFB_02467	411463.EUBVEN_00920	7.48e-94	275.0	2B9Z2@1|root,323CP@2|Bacteria,1VE7M@1239|Firmicutes,25DYU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ToxN_toxin
NHEHCBFB_02468	585394.RHOM_13325	1.02e-249	704.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,1TY16@1239|Firmicutes,24A3H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
NHEHCBFB_02469	411463.EUBVEN_00923	1.03e-206	572.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,25VEQ@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NHEHCBFB_02470	457412.RSAG_01813	3.27e-149	420.0	2B7SS@1|root,320Z4@2|Bacteria,1V805@1239|Firmicutes,24IU3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02471	585394.RHOM_13340	3.95e-251	689.0	COG1277@1|root,COG1277@2|Bacteria,1UYRU@1239|Firmicutes,24A07@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
NHEHCBFB_02472	411470.RUMGNA_03743	1.33e-274	752.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1TRZX@1239|Firmicutes,249AI@186801|Clostridia,3XYP2@572511|Blautia	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
NHEHCBFB_02473	411469.EUBHAL_02113	6.76e-159	446.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,25YCG@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_02474	411461.DORFOR_03045	1.35e-72	229.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NHEHCBFB_02475	1256908.HMPREF0373_02455	2.42e-79	236.0	COG4219@1|root,COG4219@2|Bacteria,1V1YX@1239|Firmicutes,24FVT@186801|Clostridia	186801|Clostridia	KT	Domain of unknown function (DUF4825)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4825
NHEHCBFB_02476	457412.RSAG_01820	6.57e-76	228.0	28NY7@1|root,2ZBVG@2|Bacteria,1V2J3@1239|Firmicutes,24G35@186801|Clostridia,3WJI7@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2992
NHEHCBFB_02477	742765.HMPREF9457_01261	4.78e-188	524.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_02478	552396.HMPREF0863_01518	5.33e-77	230.0	2C5R4@1|root,2ZRGD@2|Bacteria,1V4WH@1239|Firmicutes	1239|Firmicutes	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NHEHCBFB_02479	457412.RSAG_01824	0.0	1068.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WGD4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
NHEHCBFB_02480	1121115.AXVN01000080_gene890	9.76e-229	629.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia,3XZA2@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
NHEHCBFB_02481	1121115.AXVN01000080_gene889	6.65e-289	791.0	COG0265@1|root,COG0265@2|Bacteria,1TTAZ@1239|Firmicutes,24BWH@186801|Clostridia,3XZG2@572511|Blautia	186801|Clostridia	O	COG COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
NHEHCBFB_02483	1121115.AXVN01000052_gene887	0.0	1441.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,3XYKH@572511|Blautia	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
NHEHCBFB_02484	1121115.AXVN01000052_gene886	5.46e-169	471.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,3XZ5B@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_02485	1121115.AXVN01000052_gene885	0.0	917.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XZ8I@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NHEHCBFB_02486	1121115.AXVN01000052_gene884	0.0	1144.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,3XZKC@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
NHEHCBFB_02487	1121115.AXVN01000052_gene883	0.0	1350.0	COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia,3XZ82@572511|Blautia	186801|Clostridia	S	MCRA family	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
NHEHCBFB_02488	1121115.AXVN01000052_gene882	8.94e-135	381.0	COG1309@1|root,COG1309@2|Bacteria,1UYIP@1239|Firmicutes,249K5@186801|Clostridia,3XZUQ@572511|Blautia	186801|Clostridia	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NHEHCBFB_02489	1121115.AXVN01000052_gene881	1.94e-120	343.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,3XYZI@572511|Blautia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
NHEHCBFB_02490	1121115.AXVN01000052_gene880	3.44e-132	375.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,3XZIN@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
NHEHCBFB_02491	1121115.AXVN01000052_gene879	2.09e-10	55.5	28U02@1|root,2ZG6F@2|Bacteria,1W5KD@1239|Firmicutes,2551S@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02492	1121115.AXVN01000052_gene878	0.0	1123.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3XZA6@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
NHEHCBFB_02493	1121115.AXVN01000052_gene877	2.71e-66	201.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3Y0HD@572511|Blautia	186801|Clostridia	O	Thioredoxin-like domain	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NHEHCBFB_02494	457412.RSAG_01838	9.5e-209	578.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3WIBR@541000|Ruminococcaceae	186801|Clostridia	C	pyridine	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
NHEHCBFB_02495	1121115.AXVN01000052_gene875	1.11e-299	817.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3XYZQ@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
NHEHCBFB_02496	33035.JPJF01000003_gene1848	0.0	954.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia,3Y197@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
NHEHCBFB_02497	457412.RSAG_01840	5.75e-244	671.0	2BP77@1|root,32HYI@2|Bacteria,1V84J@1239|Firmicutes,24JDS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02498	457412.RSAG_01841	0.0	1419.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3WGZR@541000|Ruminococcaceae	186801|Clostridia	G	Hydrolase Family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NHEHCBFB_02499	1121115.AXVN01000052_gene872	0.0	995.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TRXY@1239|Firmicutes,24BYW@186801|Clostridia,3Y1D5@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NHEHCBFB_02500	1121115.AXVN01000052_gene871	0.0	1095.0	COG2972@1|root,COG2972@2|Bacteria,1UYIY@1239|Firmicutes,24ACA@186801|Clostridia,3Y1EM@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,dCache_1
NHEHCBFB_02501	457412.RSAG_01844	4.13e-193	536.0	COG0395@1|root,COG0395@2|Bacteria,1TRD1@1239|Firmicutes,24BQQ@186801|Clostridia,3WNYS@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NHEHCBFB_02502	457412.RSAG_01845	2.84e-209	579.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WJ61@541000|Ruminococcaceae	186801|Clostridia	P	transport systems	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NHEHCBFB_02503	457412.RSAG_01846	0.0	869.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24C14@186801|Clostridia,3WHJ4@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_02504	457412.RSAG_01846	0.0	869.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24C14@186801|Clostridia,3WHJ4@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NHEHCBFB_02505	1121115.AXVN01000052_gene867	3.37e-294	801.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,3XZHU@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
NHEHCBFB_02507	457412.RSAG_01848	0.0	862.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WH4H@541000|Ruminococcaceae	186801|Clostridia	E	O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NHEHCBFB_02508	457412.RSAG_01849	3.79e-272	744.0	COG3584@1|root,COG3584@2|Bacteria,1V7JE@1239|Firmicutes,24UNG@186801|Clostridia,3WMD0@541000|Ruminococcaceae	186801|Clostridia	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
NHEHCBFB_02509	457412.RSAG_00997	1.11e-191	531.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WIVB@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
NHEHCBFB_02510	457412.RSAG_00998	1.33e-77	230.0	2FJ0Y@1|root,34ARM@2|Bacteria,1W0GV@1239|Firmicutes,253NM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02511	457412.RSAG_04685	0.0	1107.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3WGEY@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NHEHCBFB_02512	457412.RSAG_04684	3.6e-242	664.0	COG1482@1|root,COG1482@2|Bacteria,1V0PH@1239|Firmicutes,2487K@186801|Clostridia,3WRRD@541000|Ruminococcaceae	186801|Clostridia	G	Phosphomannose isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
NHEHCBFB_02513	457412.RSAG_01001	0.0	872.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,3WI9R@541000|Ruminococcaceae	186801|Clostridia	M	Mannose-1-phosphate guanylyltransferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
NHEHCBFB_02514	457412.RSAG_01002	1.45e-234	644.0	COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,249R2@186801|Clostridia,3WH5N@541000|Ruminococcaceae	186801|Clostridia	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
NHEHCBFB_02515	457412.RSAG_01003	3.41e-258	707.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,24863@186801|Clostridia,3WHBN@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
NHEHCBFB_02516	457412.RSAG_01004	1.37e-216	597.0	COG2207@1|root,COG2207@2|Bacteria,1V1VJ@1239|Firmicutes,24G3A@186801|Clostridia,3WRI1@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NHEHCBFB_02517	457412.RSAG_04683	0.0	1949.0	COG1208@1|root,COG2605@1|root,COG1208@2|Bacteria,COG2605@2|Bacteria,1VU5A@1239|Firmicutes,24BK8@186801|Clostridia,3WJ16@541000|Ruminococcaceae	186801|Clostridia	JM	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
NHEHCBFB_02518	457412.RSAG_01007	3.45e-144	406.0	2BVMK@1|root,32QXV@2|Bacteria,1V9D0@1239|Firmicutes,24K6Z@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NHEHCBFB_02519	457412.RSAG_01008	3.11e-218	602.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3WHDJ@541000|Ruminococcaceae	186801|Clostridia	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
NHEHCBFB_02520	1541960.KQ78_01861	3.23e-07	53.9	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02521	457412.RSAG_00419	1.05e-131	373.0	COG4636@1|root,COG4636@2|Bacteria,1V8DJ@1239|Firmicutes,24G93@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NHEHCBFB_02522	457412.RSAG_00420	2.95e-122	348.0	COG4636@1|root,COG4636@2|Bacteria,1V5WZ@1239|Firmicutes,24IWJ@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NHEHCBFB_02523	1121115.AXVN01000020_gene100	3.38e-17	75.1	COG3077@1|root,COG3077@2|Bacteria,1VJC4@1239|Firmicutes,25CY3@186801|Clostridia	186801|Clostridia	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
NHEHCBFB_02524	511680.BUTYVIB_01914	9.55e-06	45.8	2E4DC@1|root,32Z8R@2|Bacteria,1VF6A@1239|Firmicutes,24QX7@186801|Clostridia,4C00Y@830|Butyrivibrio	186801|Clostridia	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	ko:K19165	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
NHEHCBFB_02525	457412.RSAG_00423	1.82e-130	370.0	COG4636@1|root,COG4636@2|Bacteria,1V1Q1@1239|Firmicutes,24ITV@186801|Clostridia,3WS1U@541000|Ruminococcaceae	1239|Firmicutes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NHEHCBFB_02527	411469.EUBHAL_01479	2.4e-29	111.0	COG3153@1|root,COG3153@2|Bacteria,1V3PW@1239|Firmicutes,24ACS@186801|Clostridia,25W14@186806|Eubacteriaceae	186801|Clostridia	S	Acetyltransferase, gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
NHEHCBFB_02528	411469.EUBHAL_01478	8.55e-43	144.0	COG1309@1|root,COG1309@2|Bacteria,1V5EA@1239|Firmicutes,25BHW@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	mtrR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NHEHCBFB_02529	500632.CLONEX_03324	1.59e-61	190.0	2CTED@1|root,32ST9@2|Bacteria,1VD31@1239|Firmicutes,24Q04@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02530	1280685.AUKC01000024_gene1104	3.68e-36	125.0	2A6DJ@1|root,30V6F@2|Bacteria,1V4WS@1239|Firmicutes,24J8E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02531	457412.RSAG_04591	1.72e-228	634.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24CRM@186801|Clostridia,3WS41@541000|Ruminococcaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
NHEHCBFB_02532	411459.RUMOBE_01252	1.1e-18	87.8	COG5492@1|root,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,3Y0E9@572511|Blautia	186801|Clostridia	N	endoglucanase-related protein, glucosyl hydrolase family 9 protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF11,DUF4430,Flg_new
NHEHCBFB_02533	457412.RSAG_01439	0.0	1654.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,3WH8W@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NHEHCBFB_02534	411473.RUMCAL_02057	5.5e-146	414.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WG7X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_02535	411473.RUMCAL_02058	7.89e-179	502.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,3WGIH@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase- DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NHEHCBFB_02536	483218.BACPEC_00282	1.91e-151	427.0	COG0745@1|root,COG0745@2|Bacteria,1TSNV@1239|Firmicutes,2493A@186801|Clostridia,268X2@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_02537	1121115.AXVN01000065_gene682	1.48e-68	216.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,3Y0WW@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_02538	1121115.AXVN01000004_gene1987	2.18e-05	45.8	COG1476@1|root,COG1476@2|Bacteria,1UUSK@1239|Firmicutes,247YW@186801|Clostridia,3Y062@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Zn_ribbon_2
NHEHCBFB_02539	457412.RSAG_00426	0.0	995.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3WGYV@541000|Ruminococcaceae	186801|Clostridia	G	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
NHEHCBFB_02540	1121115.AXVN01000004_gene1989	1.63e-43	141.0	2CIA0@1|root,341N9@2|Bacteria,1VY7T@1239|Firmicutes,251RU@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2500
NHEHCBFB_02541	411459.RUMOBE_02066	1.19e-66	209.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3XZBQ@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
NHEHCBFB_02542	478749.BRYFOR_05667	8.35e-133	389.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NHEHCBFB_02543	478749.BRYFOR_05659	8.46e-223	623.0	COG2182@1|root,COG2182@2|Bacteria,1UIC9@1239|Firmicutes,2499Z@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NHEHCBFB_02544	478749.BRYFOR_05658	3.2e-184	516.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia	186801|Clostridia	P	Abc transporter, permease protein	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NHEHCBFB_02545	478749.BRYFOR_05657	5.89e-156	443.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia	186801|Clostridia	P	sugar transport system permease	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NHEHCBFB_02546	397290.C810_02907	5.27e-257	716.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,27J9G@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 32	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
NHEHCBFB_02547	397291.C804_03708	7.99e-292	808.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,27JC3@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha-amylase domain	-	-	3.2.1.1,3.2.1.10,3.2.1.70	ko:K01176,ko:K01182,ko:K01215	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
NHEHCBFB_02548	1235798.C817_04905	0.0	1061.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,27W6B@189330|Dorea	186801|Clostridia	G	Glycogen debranching enzyme, glucanotransferase domain	-	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
NHEHCBFB_02550	457412.RSAG_03368	5.32e-122	357.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia,3WGRK@541000|Ruminococcaceae	186801|Clostridia	S	YibE/F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortase,YibE_F
NHEHCBFB_02551	936596.HMPREF1495_1309	0.0	1015.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia,1HW7D@1164882|Lachnoanaerobaculum	186801|Clostridia	L	transposase, IS4 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
NHEHCBFB_02555	1256908.HMPREF0373_02455	7.72e-69	209.0	COG4219@1|root,COG4219@2|Bacteria,1V1YX@1239|Firmicutes,24FVT@186801|Clostridia	186801|Clostridia	KT	Domain of unknown function (DUF4825)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4825
NHEHCBFB_02556	658088.HMPREF0987_00262	3.84e-41	138.0	2BCGS@1|root,3262J@2|Bacteria,1US1R@1239|Firmicutes,25A02@186801|Clostridia,27PFM@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
NHEHCBFB_02560	742765.HMPREF9457_03230	1.56e-39	134.0	295RU@1|root,2ZT35@2|Bacteria,1V63F@1239|Firmicutes,24TPB@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
NHEHCBFB_02561	457412.RSAG_00431	0.0	936.0	2E6HB@1|root,3314J@2|Bacteria,1VGBM@1239|Firmicutes,24T1M@186801|Clostridia,3WMCU@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02562	457412.RSAG_00432	2.19e-106	307.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WRUB@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NHEHCBFB_02563	457412.RSAG_00433	0.0	1047.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,24A30@186801|Clostridia,3WJX1@541000|Ruminococcaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
NHEHCBFB_02564	457412.RSAG_00434	1.62e-83	247.0	COG3682@1|root,COG3682@2|Bacteria,1VEJ8@1239|Firmicutes,24R6S@186801|Clostridia,3WKEQ@541000|Ruminococcaceae	186801|Clostridia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NHEHCBFB_02565	457412.RSAG_00435	1.34e-160	455.0	2EYFT@1|root,33RPP@2|Bacteria,1VSB0@1239|Firmicutes,24XZU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02566	457412.RSAG_00437	9.55e-70	209.0	2ASKI@1|root,31I16@2|Bacteria,1VI67@1239|Firmicutes,24A56@186801|Clostridia,3WJSX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02567	411468.CLOSCI_02125	4.22e-08	53.5	2ASKI@1|root,31I16@2|Bacteria,1VI67@1239|Firmicutes,24A56@186801|Clostridia,2242S@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02568	457412.RSAG_04741	3.17e-291	798.0	COG1106@1|root,COG1106@2|Bacteria,1TPJN@1239|Firmicutes,249WF@186801|Clostridia,3WIMF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
NHEHCBFB_02569	1121115.AXVN01000067_gene3467	1.34e-176	492.0	COG4200@1|root,COG4200@2|Bacteria,1V4AY@1239|Firmicutes,24EXR@186801|Clostridia,3Y0KJ@572511|Blautia	186801|Clostridia	S	Lantibiotic protection ABC transporter permease subunit, MutG family	mutG	-	-	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
NHEHCBFB_02570	1121115.AXVN01000067_gene3468	8.73e-81	240.0	2EQSU@1|root,33ICN@2|Bacteria,1VPW6@1239|Firmicutes,24WW2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02571	1121115.AXVN01000067_gene3469	2.25e-157	441.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,3XZUE@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_02572	1121115.AXVN01000067_gene3470	9.16e-317	864.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,3Y01W@572511|Blautia	186801|Clostridia	T	subtilin biosynthesis sensor protein SpaK	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
NHEHCBFB_02574	1121115.AXVN01000176_gene3752	8.8e-49	157.0	COG3668@1|root,COG3668@2|Bacteria,1VGR8@1239|Firmicutes,24KGA@186801|Clostridia,3Y1QZ@572511|Blautia	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
NHEHCBFB_02575	411461.DORFOR_01992	9.43e-52	163.0	COG2161@1|root,COG2161@2|Bacteria,1VA5D@1239|Firmicutes,24NDD@186801|Clostridia	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
NHEHCBFB_02576	411461.DORFOR_01990	5.78e-246	676.0	COG1396@1|root,COG1396@2|Bacteria,1V5AK@1239|Firmicutes,25EWQ@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_02577	411461.DORFOR_01989	1.8e-130	372.0	COG1476@1|root,COG1476@2|Bacteria,1V7I5@1239|Firmicutes,24KRY@186801|Clostridia,27WTV@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_02578	411461.DORFOR_01988	1.47e-79	236.0	2C5R4@1|root,2ZRGD@2|Bacteria,1V4WH@1239|Firmicutes,24HA6@186801|Clostridia,27X07@189330|Dorea	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NHEHCBFB_02579	411474.COPEUT_00022	3.43e-109	332.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
NHEHCBFB_02580	457412.RSAG_00812	7.9e-57	184.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia,3WI6V@541000|Ruminococcaceae	186801|Clostridia	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
NHEHCBFB_02581	471875.RUMLAC_01437	1.82e-160	449.0	COG0745@1|root,COG0745@2|Bacteria,1UYA6@1239|Firmicutes,24J6Y@186801|Clostridia,3WH6A@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_02582	471875.RUMLAC_01438	6.71e-211	584.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia,3WHBQ@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_02583	742765.HMPREF9457_03742	6.78e-153	431.0	2E7QB@1|root,3325S@2|Bacteria,1VH8R@1239|Firmicutes,24MW4@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
NHEHCBFB_02584	742765.HMPREF9457_03741	7.97e-168	469.0	29R1R@1|root,30C2V@2|Bacteria,1V3VM@1239|Firmicutes,24GAA@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
NHEHCBFB_02585	471875.RUMLAC_01442	3.93e-198	551.0	COG0642@1|root,COG2205@2|Bacteria,1UYK9@1239|Firmicutes,2510T@186801|Clostridia,3WHGI@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NHEHCBFB_02586	1121115.AXVN01000049_gene1310	0.0	1398.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3XZDZ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
NHEHCBFB_02587	457412.RSAG_02911	5.23e-229	630.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia,3WHA2@541000|Ruminococcaceae	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	dagK	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
NHEHCBFB_02588	457412.RSAG_02909	4.72e-199	550.0	COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,25B80@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NHEHCBFB_02589	1121115.AXVN01000049_gene1313	3.01e-179	499.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,3XYZ4@572511|Blautia	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
NHEHCBFB_02590	1121115.AXVN01000049_gene1314	2.01e-286	782.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,3XYNP@572511|Blautia	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NHEHCBFB_02591	1121115.AXVN01000049_gene1315	3.27e-145	409.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,3Y006@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
NHEHCBFB_02592	457412.RSAG_02905	1.66e-175	491.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,3WG9T@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
NHEHCBFB_02593	1121115.AXVN01000049_gene1317	1.1e-231	639.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,3XZ38@572511|Blautia	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
NHEHCBFB_02594	1121115.AXVN01000049_gene1318	1.31e-133	379.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,3XZUJ@572511|Blautia	186801|Clostridia	EH	Psort location Cytoplasmic, score 8.87	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
NHEHCBFB_02595	457412.RSAG_02902	0.0	962.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,3WHMI@541000|Ruminococcaceae	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
NHEHCBFB_02596	1235793.C809_00055	5.01e-14	70.9	COG1476@1|root,COG1476@2|Bacteria,1V7TA@1239|Firmicutes,2496Q@186801|Clostridia,27IJ5@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_02597	1121115.AXVN01000063_gene717	3.85e-103	298.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,25KA6@186801|Clostridia,3Y1KT@572511|Blautia	186801|Clostridia	P	COG COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
NHEHCBFB_02598	457412.RSAG_02093	1.1e-228	629.0	COG4823@1|root,COG4823@2|Bacteria,1V4ZD@1239|Firmicutes,24BWK@186801|Clostridia,3WRSH@541000|Ruminococcaceae	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
NHEHCBFB_02599	1410633.JHWR01000008_gene1692	5.39e-294	805.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,27JJ4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
NHEHCBFB_02600	1158608.I583_02503	2.95e-161	496.0	2D1YP@1|root,32TBQ@2|Bacteria	2|Bacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
NHEHCBFB_02601	1280698.AUJS01000081_gene3047	4.39e-182	508.0	COG3093@1|root,COG3093@2|Bacteria,1UXZS@1239|Firmicutes,24BNR@186801|Clostridia,27X3C@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_02602	411459.RUMOBE_03335	1.45e-137	390.0	COG0358@1|root,COG0358@2|Bacteria,1TT8H@1239|Firmicutes,249UB@186801|Clostridia	186801|Clostridia	L	CHC2 zinc finger domain protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
NHEHCBFB_02603	411459.RUMOBE_03334	0.0	879.0	COG3378@1|root,COG3378@2|Bacteria,1TSGZ@1239|Firmicutes,24CI8@186801|Clostridia,3Y0RF@572511|Blautia	186801|Clostridia	S	Phage plasmid primase, P4 family domain protein	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5
NHEHCBFB_02604	1280698.AUJS01000081_gene3050	2.06e-224	620.0	COG1196@1|root,COG1196@2|Bacteria,1TRNI@1239|Firmicutes,247S8@186801|Clostridia,27V0D@189330|Dorea	186801|Clostridia	D	COG NOG17369 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
NHEHCBFB_02605	411459.RUMOBE_03332	1.57e-37	126.0	29VGG@1|root,30GY0@2|Bacteria,1UGV4@1239|Firmicutes,25PFM@186801|Clostridia,3Y25Y@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02606	457412.RSAG_00564	8.42e-36	123.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	xre	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NHEHCBFB_02607	1121115.AXVN01000083_gene2460	3.85e-31	109.0	2FEN0@1|root,346MC@2|Bacteria,1VZFX@1239|Firmicutes,2532H@186801|Clostridia,3Y1ZK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02608	1121115.AXVN01000083_gene2461	1.32e-74	223.0	29VPK@1|root,30H70@2|Bacteria,1UH80@1239|Firmicutes,25PX8@186801|Clostridia,3Y1PB@572511|Blautia	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
NHEHCBFB_02609	457412.RSAG_00567	2.68e-84	248.0	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,24MVS@186801|Clostridia,3WJVE@541000|Ruminococcaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
NHEHCBFB_02610	457412.RSAG_00568	1.94e-72	218.0	296J0@1|root,2ZP02@2|Bacteria,1TTVX@1239|Firmicutes,25MY8@186801|Clostridia,3WM17@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC,RHH_1
NHEHCBFB_02611	411459.RUMOBE_00584	0.0	903.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,3XZ6Y@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NHEHCBFB_02612	411459.RUMOBE_00585	1.64e-98	285.0	COG0745@1|root,COG0745@2|Bacteria,1V65U@1239|Firmicutes,24HUB@186801|Clostridia,3Y0QH@572511|Blautia	186801|Clostridia	KT	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
NHEHCBFB_02613	411459.RUMOBE_00586	1.93e-79	236.0	COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,24N11@186801|Clostridia,3Y08G@572511|Blautia	186801|Clostridia	K	beta-lactamase (penicillinase) repressor	blaI	-	-	ko:K02171	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Penicillinase_R
NHEHCBFB_02614	411459.RUMOBE_00587	0.0	1169.0	COG2602@1|root,COG4219@1|root,COG2602@2|Bacteria,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,3XYWY@572511|Blautia	186801|Clostridia	KTV	Psort location CytoplasmicMembrane, score	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M56,Transpeptidase
NHEHCBFB_02615	411459.RUMOBE_00588	2.74e-306	834.0	28IBJ@1|root,2Z8XY@2|Bacteria,1UCWW@1239|Firmicutes,24DUG@186801|Clostridia,3XZIT@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02616	411459.RUMOBE_00589	5.98e-288	785.0	28IBJ@1|root,2Z8E0@2|Bacteria,1UYB9@1239|Firmicutes,24BIZ@186801|Clostridia,3XZZK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02617	457412.RSAG_00590	0.0	1373.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,248PI@186801|Clostridia,3WH22@541000|Ruminococcaceae	186801|Clostridia	M	NTF2-like N-terminal transpeptidase domain	pbpC	-	3.4.16.4	ko:K05515,ko:K21467	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
NHEHCBFB_02618	1121115.AXVN01000154_gene3993	1.16e-48	156.0	2E96C@1|root,333EY@2|Bacteria,1VEKX@1239|Firmicutes,24SUX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02619	457412.RSAG_01600	1.36e-168	472.0	COG4200@1|root,COG4200@2|Bacteria,1TRGZ@1239|Firmicutes,2498Y@186801|Clostridia,3WNQP@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K20461	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
NHEHCBFB_02620	1121115.AXVN01000154_gene3995	1.3e-155	438.0	COG4200@1|root,COG4200@2|Bacteria,1TP4G@1239|Firmicutes,249XU@186801|Clostridia,3Y26T@572511|Blautia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K20460	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
NHEHCBFB_02621	1121115.AXVN01000154_gene3996	1.61e-176	492.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,3Y1EC@572511|Blautia	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K20459	ko02010,map02010	M00254,M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
NHEHCBFB_02622	1121115.AXVN01000154_gene3997	1.44e-164	460.0	COG0745@1|root,COG0745@2|Bacteria,1TYPK@1239|Firmicutes,247Y9@186801|Clostridia,3Y11C@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_02623	1121115.AXVN01000154_gene3998	0.0	880.0	COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,24AAW@186801|Clostridia,3Y16H@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NHEHCBFB_02624	622312.ROSEINA2194_00554	3.05e-104	301.0	28PS7@1|root,2ZCDT@2|Bacteria,1V252@1239|Firmicutes,24GY8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02625	537007.BLAHAN_05371	2.09e-154	437.0	COG4200@1|root,COG4200@2|Bacteria,1TT70@1239|Firmicutes,24ANA@186801|Clostridia,3Y0J5@572511|Blautia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
NHEHCBFB_02626	742765.HMPREF9457_03145	3.1e-173	484.0	COG1668@1|root,COG1668@2|Bacteria,1U5Z3@1239|Firmicutes,24AXX@186801|Clostridia,27WN5@189330|Dorea	186801|Clostridia	CP	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K19310	ko02010,map02010	M00254,M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.131.1	-	-	ABC2_membrane_4
NHEHCBFB_02627	742765.HMPREF9457_03144	2.66e-218	602.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K19309	ko02010,map02010	M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.131.1	-	-	ABC_tran
NHEHCBFB_02628	1121115.AXVN01000151_gene3974	1.2e-208	578.0	COG0642@1|root,COG2205@2|Bacteria,1TXC7@1239|Firmicutes,2492E@186801|Clostridia,3Y2AT@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NHEHCBFB_02629	1121115.AXVN01000151_gene3973	9.41e-164	458.0	COG0745@1|root,COG0745@2|Bacteria,1TSCM@1239|Firmicutes,248K7@186801|Clostridia,3Y1AC@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_02630	1121115.AXVN01000151_gene3972	3.2e-41	135.0	COG2909@1|root,COG2909@2|Bacteria,1VGAF@1239|Firmicutes,24SMP@186801|Clostridia,3Y0SH@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NHEHCBFB_02631	411461.DORFOR_03161	4.65e-20	92.8	COG0582@1|root,COG0582@2|Bacteria,1TSR6@1239|Firmicutes,249IV@186801|Clostridia,27WNF@189330|Dorea	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
NHEHCBFB_02632	457412.RSAG_00673	1.41e-301	825.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,3WHDK@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_02633	1235798.C817_03061	3.48e-253	709.0	COG1672@1|root,COG1672@2|Bacteria,1TPQR@1239|Firmicutes,24AIK@186801|Clostridia	186801|Clostridia	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,PDDEXK_3
NHEHCBFB_02634	457412.RSAG_00674	8.24e-242	665.0	COG2267@1|root,COG2267@2|Bacteria,1V2IH@1239|Firmicutes,24BN4@186801|Clostridia,3WPQY@541000|Ruminococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
NHEHCBFB_02635	457412.RSAG_00675	0.0	870.0	COG2211@1|root,COG2211@2|Bacteria,1TR5B@1239|Firmicutes,249ZF@186801|Clostridia,3WGZS@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NHEHCBFB_02636	411459.RUMOBE_00755	6.01e-96	286.0	COG1309@1|root,COG1309@2|Bacteria,1TYNZ@1239|Firmicutes,24IV3@186801|Clostridia	186801|Clostridia	K	transcriptional regulator TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NHEHCBFB_02637	742765.HMPREF9457_02207	6.11e-276	767.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,27W7Y@189330|Dorea	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NHEHCBFB_02638	1121115.AXVN01000043_gene3384	1.07e-184	525.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3Y131@572511|Blautia	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NHEHCBFB_02639	1121115.AXVN01000026_gene997	3.56e-193	539.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3XZ81@572511|Blautia	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
NHEHCBFB_02640	457412.RSAG_00494	3.53e-172	481.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
NHEHCBFB_02641	457412.RSAG_00495	2.73e-164	461.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,3WHTI@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NHEHCBFB_02642	1121115.AXVN01000026_gene991	2.31e-161	454.0	COG1266@1|root,COG1266@2|Bacteria,1W749@1239|Firmicutes,25MB2@186801|Clostridia,3Y0CJ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Abi
NHEHCBFB_02643	457412.RSAG_00500	7.77e-151	424.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,3WITI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NHEHCBFB_02644	1121115.AXVN01000026_gene989	3.1e-141	410.0	2CAM6@1|root,33TP6@2|Bacteria,1VTBW@1239|Firmicutes,24Z6R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02645	457412.RSAG_00502	2.15e-300	819.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,3WIN0@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
NHEHCBFB_02646	1121115.AXVN01000026_gene987	0.0	1166.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,3XZ10@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
NHEHCBFB_02647	1121115.AXVN01000026_gene986	1.11e-201	559.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,248N9@186801|Clostridia,3XYTV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NHEHCBFB_02648	1121115.AXVN01000026_gene985	0.0	1016.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3XZ65@572511|Blautia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
NHEHCBFB_02649	1121115.AXVN01000026_gene984	2.97e-54	169.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NHEHCBFB_02650	1121115.AXVN01000026_gene983	4.05e-285	781.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3XZ33@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NHEHCBFB_02651	457412.RSAG_00508	0.0	1192.0	COG0845@1|root,COG0845@2|Bacteria,1UZ3U@1239|Firmicutes,24BV7@186801|Clostridia,3WI0T@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
NHEHCBFB_02652	457412.RSAG_00509	2.59e-153	431.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3WGVE@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_02653	1121115.AXVN01000029_gene632	8.32e-268	743.0	COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,24ANJ@186801|Clostridia,3XYZR@572511|Blautia	186801|Clostridia	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NHEHCBFB_02654	1121115.AXVN01000029_gene633	3.13e-274	752.0	2F32Z@1|root,33VY0@2|Bacteria,1VRWP@1239|Firmicutes,25PV9@186801|Clostridia,3XZBM@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02655	1121115.AXVN01000029_gene634	4.97e-170	476.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,24A0G@186801|Clostridia,3XZD6@572511|Blautia	186801|Clostridia	S	Sulfite exporter TauE/SafE	yfcA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
NHEHCBFB_02656	1121115.AXVN01000029_gene635	0.0	1170.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,3XZ1M@572511|Blautia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
NHEHCBFB_02657	1121115.AXVN01000029_gene636	4.11e-293	800.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,3XYX1@572511|Blautia	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
NHEHCBFB_02658	457412.RSAG_00515	3.3e-159	446.0	COG2206@1|root,COG2206@2|Bacteria,1V54U@1239|Firmicutes,24HUA@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5
NHEHCBFB_02659	457412.RSAG_00516	0.0	991.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,3WGA8@541000|Ruminococcaceae	186801|Clostridia	C	Coproporphyrinogen dehydrogenase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NHEHCBFB_02660	1121115.AXVN01000029_gene639	8.82e-154	431.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,3Y04N@572511|Blautia	186801|Clostridia	S	COG COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
NHEHCBFB_02661	1121115.AXVN01000029_gene640	0.0	1501.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,3XZ3M@572511|Blautia	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
NHEHCBFB_02662	1121115.AXVN01000029_gene641	4.17e-119	340.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,3XZ59@572511|Blautia	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
NHEHCBFB_02663	1121115.AXVN01000029_gene642	0.0	1114.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3XZHQ@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
NHEHCBFB_02664	1121115.AXVN01000029_gene643	0.0	1431.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,3XYSY@572511|Blautia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
NHEHCBFB_02665	1121115.AXVN01000029_gene644	0.0	941.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,3XZ42@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
NHEHCBFB_02666	1121115.AXVN01000029_gene645	1.83e-20	81.6	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,3Y0JJ@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score 8.82	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
NHEHCBFB_02667	1121115.AXVN01000029_gene646	4.88e-72	217.0	2E3KV@1|root,32YJ5@2|Bacteria,1VEHD@1239|Firmicutes,24RP3@186801|Clostridia,3Y0RE@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF3792
NHEHCBFB_02668	1121115.AXVN01000029_gene647	8.78e-255	710.0	2ENTE@1|root,33GEK@2|Bacteria,1VSB4@1239|Firmicutes,24YR1@186801|Clostridia,3XZII@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02669	457412.RSAG_00526	7.88e-287	786.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WGDS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
NHEHCBFB_02670	457412.RSAG_00527	2.09e-143	404.0	COG1434@1|root,COG1434@2|Bacteria,1V32X@1239|Firmicutes,24ATY@186801|Clostridia,3WITP@541000|Ruminococcaceae	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
NHEHCBFB_02671	1121115.AXVN01000029_gene650	7.41e-157	442.0	COG0860@1|root,COG0860@2|Bacteria,1TS91@1239|Firmicutes,25B1N@186801|Clostridia,3XZHM@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	cwlC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SPOR
NHEHCBFB_02672	1121115.AXVN01000029_gene651	1.05e-225	623.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3XZPA@572511|Blautia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
NHEHCBFB_02673	457412.RSAG_00530	2.82e-207	574.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3WGJI@541000|Ruminococcaceae	186801|Clostridia	S	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
NHEHCBFB_02674	1121115.AXVN01000029_gene653	2.56e-178	498.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3XZ9G@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
NHEHCBFB_02675	1121115.AXVN01000029_gene654	5.92e-235	645.0	2EWQA@1|root,33TE1@2|Bacteria,1VR3E@1239|Firmicutes,24ZHT@186801|Clostridia,3Y1M8@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02676	457412.RSAG_00533	8.03e-116	331.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,3WIXC@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
NHEHCBFB_02677	1095750.HMPREF9970_0829	1.56e-228	637.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,1HW2I@1164882|Lachnoanaerobaculum	186801|Clostridia	L	DNA binding domain of tn916 integrase	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
NHEHCBFB_02678	1095750.HMPREF9970_0828	2.74e-32	113.0	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24MZT@186801|Clostridia,1HWEZ@1164882|Lachnoanaerobaculum	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NHEHCBFB_02679	97139.C824_04157	5.85e-36	124.0	2AJW5@1|root,334PM@2|Bacteria,1VGBA@1239|Firmicutes,25CSN@186801|Clostridia,36X06@31979|Clostridiaceae	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NHEHCBFB_02680	411459.RUMOBE_00575	4.87e-65	201.0	COG1191@1|root,COG1191@2|Bacteria,1UJZK@1239|Firmicutes,25FFS@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
NHEHCBFB_02681	1235793.C809_01444	1.09e-51	166.0	COG1476@1|root,COG1476@2|Bacteria,1V5YG@1239|Firmicutes,24IUV@186801|Clostridia,27TDC@186928|unclassified Lachnospiraceae	1239|Firmicutes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_02682	1235793.C809_00232	6.37e-31	112.0	2BPCF@1|root,33MKZ@2|Bacteria,1VM2Z@1239|Firmicutes,251G2@186801|Clostridia,27SQS@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02683	411459.RUMOBE_00579	8.1e-39	130.0	COG1396@1|root,COG1396@2|Bacteria,1VDA0@1239|Firmicutes,24PY4@186801|Clostridia,3Y0GH@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NHEHCBFB_02684	1121115.AXVN01000083_gene2460	2.56e-18	77.0	2FEN0@1|root,346MC@2|Bacteria,1VZFX@1239|Firmicutes,2532H@186801|Clostridia,3Y1ZK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02685	1121115.AXVN01000083_gene2461	1.34e-20	84.3	29VPK@1|root,30H70@2|Bacteria,1UH80@1239|Firmicutes,25PX8@186801|Clostridia,3Y1PB@572511|Blautia	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
NHEHCBFB_02686	1235798.C817_04843	3.28e-49	161.0	COG0745@1|root,COG0745@2|Bacteria,1VCPH@1239|Firmicutes,24MRK@186801|Clostridia,27VVY@189330|Dorea	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
NHEHCBFB_02687	1405.DJ92_168	9.44e-107	315.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,1ZCDW@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_02688	1405.DJ92_167	1.2e-215	624.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli,1ZBJC@1386|Bacillus	91061|Bacilli	V	ABC transporter (permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NHEHCBFB_02689	1405.DJ92_166	1e-91	297.0	COG4585@1|root,COG4585@2|Bacteria,1UM5K@1239|Firmicutes,4HQKB@91061|Bacilli	91061|Bacilli	T	Histidine kinase	-	-	-	ko:K14988	ko02020,map02020	M00522	-	-	ko00000,ko00001,ko00002,ko01001,ko02022	-	-	-	-
NHEHCBFB_02690	1235800.C819_04162	1.37e-80	245.0	COG2197@1|root,COG2197@2|Bacteria,1V0R9@1239|Firmicutes,24KFI@186801|Clostridia	186801|Clostridia	K	Response regulator receiver domain protein	-	-	-	ko:K14989	ko02020,map02020	M00522	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
NHEHCBFB_02691	411459.RUMOBE_00583	4.2e-58	181.0	296J0@1|root,2ZR9N@2|Bacteria,1VAUS@1239|Firmicutes,24PMT@186801|Clostridia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
NHEHCBFB_02692	1121115.AXVN01000083_gene2463	4.93e-205	582.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,3XZ6Y@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NHEHCBFB_02693	658088.HMPREF0987_02720	4.72e-107	308.0	COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,25CMS@186801|Clostridia,27U60@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
NHEHCBFB_02694	622312.ROSEINA2194_04253	1.78e-187	549.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NHEHCBFB_02695	1121115.AXVN01000056_gene2501	3.53e-150	423.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3XYM9@572511|Blautia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_02696	457412.RSAG_00875	4.25e-228	630.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,3WI2K@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NHEHCBFB_02697	1121115.AXVN01000056_gene2499	2.39e-72	221.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,249PK@186801|Clostridia,3XZNU@572511|Blautia	186801|Clostridia	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_02698	1121115.AXVN01000056_gene2499	4.87e-69	213.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,249PK@186801|Clostridia,3XZNU@572511|Blautia	186801|Clostridia	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_02699	1232447.BAHW02000010_gene558	7.94e-17	72.4	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
NHEHCBFB_02700	1160721.RBI_I01301	8.66e-88	268.0	COG4509@1|root,COG4509@2|Bacteria,1V7UG@1239|Firmicutes,24KBR@186801|Clostridia,3WJMA@541000|Ruminococcaceae	186801|Clostridia	S	Sortase family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NHEHCBFB_02701	1235799.C818_03892	1.53e-100	356.0	COG1669@1|root,COG2003@1|root,COG4227@1|root,COG1669@2|Bacteria,COG2003@2|Bacteria,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,27IQS@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1738,DUF3849,DUF4316,Peptidase_M78,YodL
NHEHCBFB_02702	226185.EF_2319	1e-21	101.0	28N5R@1|root,2ZBAW@2|Bacteria,1UZ09@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02703	397291.C804_03023	4.97e-104	322.0	COG0553@1|root,COG0553@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia,27IX0@186928|unclassified Lachnospiraceae	186801|Clostridia	KL	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3849,Helicase_C,ResIII,SNF2_N
NHEHCBFB_02704	1121864.OMO_01631	0.0	1224.0	COG1961@1|root,COG1961@2|Bacteria,1TP0S@1239|Firmicutes,4HBBX@91061|Bacilli,4B6EH@81852|Enterococcaceae	91061|Bacilli	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NHEHCBFB_02705	1121864.OMO_01632	4.17e-55	172.0	2AH2U@1|root,317C4@2|Bacteria,1V7XU@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02706	1121864.OMO_01633	1.99e-48	154.0	COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,4HNSP@91061|Bacilli	91061|Bacilli	S	protein conserved in bacteria	XK26_06125	-	-	-	-	-	-	-	-	-	-	-	PC4
NHEHCBFB_02707	1123489.AUAN01000007_gene422	7.99e-192	533.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,4H7H6@909932|Negativicutes	909932|Negativicutes	K	ParB-like nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
NHEHCBFB_02708	1121864.OMO_01635	9.01e-228	627.0	COG1196@1|root,COG1196@2|Bacteria,1TRNI@1239|Firmicutes,4HHXH@91061|Bacilli,4B4B0@81852|Enterococcaceae	91061|Bacilli	D	Plasmid recombination enzyme	XK26_06135	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
NHEHCBFB_02709	1121864.OMO_01636	2.02e-244	671.0	COG0468@1|root,COG0468@2|Bacteria,1V9SB@1239|Firmicutes	1239|Firmicutes	L	Psort location Cytoplasmic, score 8.87	XK27_03350	-	-	-	-	-	-	-	-	-	-	-	AAA_25
NHEHCBFB_02710	1121864.OMO_01637	1.71e-109	314.0	28KFR@1|root,2ZA1S@2|Bacteria,1V0WW@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02711	1121864.OMO_01638	7.15e-95	276.0	COG1595@1|root,COG1595@2|Bacteria,1UYSW@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
NHEHCBFB_02712	1121864.OMO_01639	6.96e-116	332.0	COG1191@1|root,COG1191@2|Bacteria,1V1GF@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score	XK26_06155	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
NHEHCBFB_02713	1232452.BAIB02000009_gene1940	2.29e-273	750.0	COG0738@1|root,COG0738@2|Bacteria,1UJ6C@1239|Firmicutes,2494T@186801|Clostridia	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	ko:K18214	-	-	-	-	ko00000,ko01504,ko02000	2.A.1.21.6	-	-	MFS_1
NHEHCBFB_02714	411462.DORLON_02667	0.0	1273.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,27V24@189330|Dorea	186801|Clostridia	J	Elongation factor G, domain IV	-	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
NHEHCBFB_02715	1121864.OMO_01641	2.34e-85	251.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NHEHCBFB_02716	585394.RHOM_15365	0.0	2747.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia	186801|Clostridia	L	helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3849,Helicase_C,ResIII,SNF2_N
NHEHCBFB_02717	485916.Dtox_3880	1.22e-22	96.7	2E9D4@1|root,30W3F@2|Bacteria,1VWWW@1239|Firmicutes,2522P@186801|Clostridia	186801|Clostridia	S	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
NHEHCBFB_02718	478749.BRYFOR_09005	2.32e-45	154.0	COG1396@1|root,COG1396@2|Bacteria,1UYE6@1239|Firmicutes,24CI9@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NHEHCBFB_02719	97138.C820_02863	1.02e-90	280.0	COG1032@1|root,COG1032@2|Bacteria,1TRY3@1239|Firmicutes,249Q1@186801|Clostridia,36HCS@31979|Clostridiaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02720	1121333.JMLH01000033_gene2895	0.0	2628.0	COG4932@1|root,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,3VP4C@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02721	742741.HMPREF9475_02329	4.12e-304	852.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	DUF3945,Topoisom_bac,Toprim,Toprim_Crpt
NHEHCBFB_02722	1408437.JNJN01000002_gene1394	3.74e-06	48.9	29SBN@1|root,30DG6@2|Bacteria,1UB9A@1239|Firmicutes,24VZQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02723	411459.RUMOBE_00624	4.51e-145	431.0	COG2433@1|root,COG2433@2|Bacteria,1UI9E@1239|Firmicutes,25EEA@186801|Clostridia	186801|Clostridia	T	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
NHEHCBFB_02725	411459.RUMOBE_00626	0.0	1132.0	COG0739@1|root,COG0791@1|root,COG3064@1|root,COG3584@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria,COG3064@2|Bacteria,COG3584@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,3XYSD@572511|Blautia	186801|Clostridia	M	Psort location Extracellular, score 9.55	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,Peptidase_M23
NHEHCBFB_02726	411459.RUMOBE_00627	0.0	1321.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,3XZH0@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
NHEHCBFB_02727	411459.RUMOBE_00628	1.4e-72	220.0	28PED@1|root,2ZC92@2|Bacteria,1V3ND@1239|Firmicutes,24G75@186801|Clostridia,3Y0GB@572511|Blautia	186801|Clostridia	S	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
NHEHCBFB_02728	411459.RUMOBE_00629	1.84e-184	515.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,248SU@186801|Clostridia,3XYX7@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02729	500632.CLONEX_01846	0.0	1112.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NHEHCBFB_02730	500632.CLONEX_01848	5.4e-39	129.0	2CCGJ@1|root,32RVM@2|Bacteria,1VAEN@1239|Firmicutes,24MRI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02731	411483.FAEPRAA2165_00582	0.0	905.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,3WHVZ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	VirE
NHEHCBFB_02732	742741.HMPREF9475_02750	2.81e-148	417.0	COG0358@1|root,COG0358@2|Bacteria,1TRW1@1239|Firmicutes,249RY@186801|Clostridia,220YX@1506553|Lachnoclostridium	186801|Clostridia	L	CHC2 zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
NHEHCBFB_02733	411473.RUMCAL_01407	0.0	1004.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,3WGDP@541000|Ruminococcaceae	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NHEHCBFB_02734	1235798.C817_01266	2.5e-110	318.0	COG0597@1|root,COG0597@2|Bacteria,1VF2W@1239|Firmicutes,24AS6@186801|Clostridia	186801|Clostridia	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
NHEHCBFB_02735	1235835.C814_02880	1.25e-67	205.0	COG3070@1|root,COG3070@2|Bacteria,1V42M@1239|Firmicutes,24JNV@186801|Clostridia,3WJXD@541000|Ruminococcaceae	186801|Clostridia	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
NHEHCBFB_02736	665956.HMPREF1032_03410	2.01e-58	181.0	2B26K@1|root,31UPX@2|Bacteria,1V93Z@1239|Firmicutes,24JA0@186801|Clostridia,3WJCW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
NHEHCBFB_02737	1235800.C819_00860	1.72e-75	225.0	COG1349@1|root,COG1349@2|Bacteria,1V4EI@1239|Firmicutes,24HRM@186801|Clostridia,27MZ4@186928|unclassified Lachnospiraceae	186801|Clostridia	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
NHEHCBFB_02738	1235835.C814_02883	1.08e-39	131.0	2CBNR@1|root,32T16@2|Bacteria,1VA97@1239|Firmicutes,24NAW@186801|Clostridia,3WJUG@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02739	411473.RUMCAL_01414	6.11e-188	522.0	COG1396@1|root,COG1396@2|Bacteria,1TT2N@1239|Firmicutes,2488F@186801|Clostridia,3WHQ4@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NHEHCBFB_02740	411473.RUMCAL_01415	1.99e-235	647.0	28J81@1|root,2Z939@2|Bacteria,1V03Q@1239|Firmicutes,24DBV@186801|Clostridia,3WJQA@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835,DUF3658
NHEHCBFB_02741	411467.BACCAP_03284	1.84e-87	256.0	2C5R4@1|root,2ZBQ6@2|Bacteria,1V1T6@1239|Firmicutes,24GMD@186801|Clostridia,269FK@186813|unclassified Clostridiales	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NHEHCBFB_02742	1121115.AXVN01000013_gene3189	1.94e-59	183.0	COG3655@1|root,COG3655@2|Bacteria,1V27G@1239|Firmicutes,24I0W@186801|Clostridia,3Y09X@572511|Blautia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
NHEHCBFB_02743	1121115.AXVN01000013_gene3190	0.0	1065.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYWF@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NHEHCBFB_02744	1121115.AXVN01000013_gene3191	1.24e-39	131.0	2DNP9@1|root,32YE1@2|Bacteria,1VEMU@1239|Firmicutes,24N4S@186801|Clostridia,3Y0IW@572511|Blautia	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
NHEHCBFB_02745	1121115.AXVN01000013_gene3192	6.01e-212	584.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,3XZBX@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
NHEHCBFB_02746	1121115.AXVN01000013_gene3193	4.49e-179	498.0	COG1349@1|root,COG1349@2|Bacteria,1TSUV@1239|Firmicutes,24CQC@186801|Clostridia,3Y084@572511|Blautia	186801|Clostridia	GK	Replication initiator protein A (RepA) N-terminus	repA	-	-	-	-	-	-	-	-	-	-	-	RepA_N
NHEHCBFB_02747	658086.HMPREF0994_06819	0.0	1066.0	COG3843@1|root,COG3843@2|Bacteria,1TR9B@1239|Firmicutes,24A36@186801|Clostridia,27IJ8@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NHEHCBFB_02748	1121115.AXVN01000013_gene3196	1.18e-86	255.0	2C2YH@1|root,2ZBKZ@2|Bacteria,1V3N8@1239|Firmicutes,24FYJ@186801|Clostridia,3Y082@572511|Blautia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
NHEHCBFB_02749	411902.CLOBOL_04284	1.6e-108	313.0	2EWMS@1|root,30FQV@2|Bacteria,1UEFU@1239|Firmicutes,25JCN@186801|Clostridia,2223E@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02750	1121115.AXVN01000013_gene3197	9.71e-74	220.0	2F2W4@1|root,33VRY@2|Bacteria,1VW1H@1239|Firmicutes,250T7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02751	397288.C806_03640	1.29e-20	82.0	2CDEH@1|root,32YRT@2|Bacteria,1VFMR@1239|Firmicutes,24QUE@186801|Clostridia	186801|Clostridia	S	Maff2 family	-	-	-	-	-	-	-	-	-	-	-	-	Maff2
NHEHCBFB_02752	411459.RUMOBE_00643	5.39e-163	457.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,3XYP3@572511|Blautia	186801|Clostridia	U	COG COG3505 Type IV secretory pathway, VirD4 components	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
NHEHCBFB_02753	552396.HMPREF0863_00449	7.63e-85	249.0	28NST@1|root,2ZBRP@2|Bacteria,1V1QP@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02754	585394.RHOM_15490	6.68e-35	119.0	2E8ED@1|root,32T9Y@2|Bacteria,1VDYN@1239|Firmicutes,24NI7@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
NHEHCBFB_02755	500632.CLONEX_01751	6.9e-199	551.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
NHEHCBFB_02756	411483.FAEPRAA2165_01988	3.61e-162	456.0	COG3935@1|root,COG3935@2|Bacteria,1TQ65@1239|Firmicutes,249Q8@186801|Clostridia,3WNVW@541000|Ruminococcaceae	186801|Clostridia	L	N-terminal phage replisome organiser (Phage_rep_org_N)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_rep_org_N
NHEHCBFB_02757	1121115.AXVN01000013_gene3205	5.31e-58	179.0	COG3077@1|root,COG3077@2|Bacteria,1VABY@1239|Firmicutes,24PQZ@186801|Clostridia	186801|Clostridia	L	Addiction module antitoxin, RelB DinJ family	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
NHEHCBFB_02758	1121115.AXVN01000013_gene3206	1.23e-49	159.0	COG3041@1|root,COG3041@2|Bacteria,1VENE@1239|Firmicutes,24MW1@186801|Clostridia,3Y0QQ@572511|Blautia	186801|Clostridia	S	Bacterial toxin of type II toxin-antitoxin system, YafQ	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
NHEHCBFB_02759	1121115.AXVN01000013_gene3207	3.95e-297	815.0	COG0507@1|root,COG1196@1|root,COG0507@2|Bacteria,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,3XZH8@572511|Blautia	186801|Clostridia	D	COG COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NHEHCBFB_02760	552396.HMPREF0863_00457	1.28e-51	164.0	2BAGF@1|root,323X1@2|Bacteria,1V6WJ@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
NHEHCBFB_02761	552396.HMPREF0863_00458	1.51e-104	302.0	COG1595@1|root,COG1595@2|Bacteria,1VBQS@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
NHEHCBFB_02762	411483.FAEPRAA2165_01995	3.33e-102	296.0	COG1595@1|root,COG1595@2|Bacteria,1TRYZ@1239|Firmicutes,24AED@186801|Clostridia,3WNHN@541000|Ruminococcaceae	186801|Clostridia	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
NHEHCBFB_02763	552396.HMPREF0863_00460	2.95e-92	270.0	COG1595@1|root,COG1595@2|Bacteria,1V70T@1239|Firmicutes	1239|Firmicutes	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2,UPF0122
NHEHCBFB_02764	1235793.C809_01700	5.43e-255	700.0	COG1277@1|root,COG1277@2|Bacteria,1UKNF@1239|Firmicutes,25G02@186801|Clostridia,27UK2@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02765	1121115.AXVN01000013_gene3212	1.16e-208	577.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3XZE4@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_02766	1235793.C809_01698	2.03e-176	492.0	2DQD6@1|root,3361N@2|Bacteria,1VJIC@1239|Firmicutes,25DE9@186801|Clostridia,27PQB@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02767	1121115.AXVN01000013_gene3213	1.94e-53	171.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NHEHCBFB_02768	1121115.AXVN01000013_gene3214	9.61e-84	247.0	COG1396@1|root,COG1396@2|Bacteria,1V331@1239|Firmicutes,24G00@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
NHEHCBFB_02769	500632.CLONEX_01766	5.28e-68	205.0	2E6DS@1|root,333AA@2|Bacteria,1VGCH@1239|Firmicutes,24N8Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02770	1121115.AXVN01000013_gene3216	3.8e-79	235.0	2DH2E@1|root,2ZY5K@2|Bacteria,1UK9H@1239|Firmicutes,25FRH@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NHEHCBFB_02771	500632.CLONEX_01768	0.0	1210.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NHEHCBFB_02772	411459.RUMOBE_00652	1.26e-211	617.0	COG1961@1|root,COG3505@1|root,COG1961@2|Bacteria,COG3505@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYWF@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,T4SS-DNA_transf,Zn_ribbon_recom
NHEHCBFB_02773	411459.RUMOBE_00653	2.33e-67	207.0	28I1B@1|root,30E9T@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
NHEHCBFB_02774	1232447.BAHW02000027_gene2070	5.43e-13	68.6	2DP32@1|root,330AW@2|Bacteria,1VGSG@1239|Firmicutes,24Q56@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02775	428126.CLOSPI_00352	3.89e-86	260.0	COG1647@1|root,COG1647@2|Bacteria,1UJX0@1239|Firmicutes,3VQMR@526524|Erysipelotrichia	526524|Erysipelotrichia	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02776	1235835.C814_00242	9.39e-08	50.8	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,24MVS@186801|Clostridia,3WJVE@541000|Ruminococcaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
NHEHCBFB_02777	610130.Closa_3684	1.82e-36	126.0	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,24MVS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
NHEHCBFB_02778	411459.RUMOBE_00654	2.95e-109	323.0	2D7U9@1|root,32TPR@2|Bacteria,1VAQE@1239|Firmicutes,24I5R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02779	411459.RUMOBE_00655	1.48e-44	147.0	COG1396@1|root,COG1396@2|Bacteria,1UZN9@1239|Firmicutes,24APP@186801|Clostridia,3Y0S7@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_02782	1235792.C808_02243	5.41e-27	103.0	2BAQE@1|root,3245B@2|Bacteria,1V86A@1239|Firmicutes,24MCZ@186801|Clostridia,27PSB@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02783	411459.RUMOBE_00659	2.52e-129	382.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia,3XZD0@572511|Blautia	186801|Clostridia	S	Replication initiator protein A (RepA) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
NHEHCBFB_02784	500632.CLONEX_01890	5.81e-121	355.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
NHEHCBFB_02785	411459.RUMOBE_00663	8.92e-144	410.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,3XZBU@572511|Blautia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
NHEHCBFB_02786	1235793.C809_01463	2.84e-20	82.0	2C7EF@1|root,33FU0@2|Bacteria,1VMPB@1239|Firmicutes,25PQ4@186801|Clostridia,27QDU@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02787	500632.CLONEX_01893	2.63e-88	261.0	2CUHA@1|root,2ZNG3@2|Bacteria,1V21P@1239|Firmicutes,24G2N@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02788	1235800.C819_04177	1.29e-171	492.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,27IJX@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
NHEHCBFB_02789	592026.GCWU0000282_000436	9.41e-21	84.7	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24MZT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NHEHCBFB_02794	457412.RSAG_04733	1.35e-161	456.0	COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,249NG@186801|Clostridia,3WKE9@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36
NHEHCBFB_02795	272562.CA_C1950	4.23e-09	54.7	COG3655@1|root,COG3655@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	DUF4384,HTH_26,HTH_3
NHEHCBFB_02796	646529.Desaci_1981	1.69e-70	219.0	COG1961@1|root,COG1961@2|Bacteria,1V51N@1239|Firmicutes,24D8I@186801|Clostridia	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
NHEHCBFB_02799	457412.RSAG_00284	6.34e-180	503.0	2FCB7@1|root,344ET@2|Bacteria,1VZX4@1239|Firmicutes,253ZT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02800	457412.RSAG_00285	1.22e-59	184.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hupT	-	-	ko:K03530,ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
NHEHCBFB_02802	397288.C806_01267	9.91e-145	431.0	2EPQE@1|root,33HAZ@2|Bacteria,1VM8T@1239|Firmicutes,24EDI@186801|Clostridia	186801|Clostridia	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
NHEHCBFB_02803	397288.C806_01263	1.22e-09	55.5	2ESSD@1|root,33KAT@2|Bacteria,1VPPK@1239|Firmicutes,24WZI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02806	411459.RUMOBE_02216	4.85e-286	785.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYKT@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_02807	1121115.AXVN01000100_gene838	0.0	1658.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3XZ58@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
NHEHCBFB_02808	457412.RSAG_00670	0.0	972.0	COG2733@1|root,COG2733@2|Bacteria,1UKI3@1239|Firmicutes,24WBV@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
NHEHCBFB_02809	1121115.AXVN01000100_gene836	6.45e-60	185.0	2CTB7@1|root,32VEP@2|Bacteria,1VD77@1239|Firmicutes,24KKI@186801|Clostridia,3Y0H9@572511|Blautia	186801|Clostridia	S	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NHEHCBFB_02810	1121115.AXVN01000100_gene835	1.21e-59	184.0	COG4577@1|root,COG4577@2|Bacteria,1VHU0@1239|Firmicutes,24PP6@186801|Clostridia,3Y0PM@572511|Blautia	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NHEHCBFB_02811	1121115.AXVN01000100_gene834	1.05e-95	281.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,3Y08H@572511|Blautia	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
NHEHCBFB_02812	1121115.AXVN01000100_gene833	1.95e-118	338.0	COG3194@1|root,COG3194@2|Bacteria,1VC6W@1239|Firmicutes,24HRJ@186801|Clostridia,3Y1H1@572511|Blautia	186801|Clostridia	F	Ureidoglycolate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Ureidogly_lyase
NHEHCBFB_02813	1121115.AXVN01000100_gene832	1.63e-194	540.0	COG4820@1|root,COG4820@2|Bacteria,1TQVV@1239|Firmicutes,249HD@186801|Clostridia,3Y15N@572511|Blautia	186801|Clostridia	E	Type IV pilus assembly protein PilM;	eutJ	-	-	ko:K04024	-	-	-	-	ko00000	-	-	-	FtsA,MreB_Mbl,PilM_2
NHEHCBFB_02814	929506.CbC4_0363	6e-167	573.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,36GGX@31979|Clostridiaceae	186801|Clostridia	M	TIGRFAM RHS repeat-associated core	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
NHEHCBFB_02816	457412.RSAG_02162	4.35e-143	404.0	2CKNK@1|root,306D0@2|Bacteria,1TZJW@1239|Firmicutes,2513T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02817	1121115.AXVN01000022_gene1759	1.11e-113	331.0	2F19F@1|root,33UAG@2|Bacteria,1VUX8@1239|Firmicutes,250KD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02819	1235802.C823_02102	6.35e-87	278.0	COG3290@1|root,COG3290@2|Bacteria,1V225@1239|Firmicutes,24DB7@186801|Clostridia,25YP8@186806|Eubacteriaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NHEHCBFB_02820	1235802.C823_02101	1.05e-90	275.0	COG3279@1|root,COG3279@2|Bacteria,1V1GQ@1239|Firmicutes,24H3F@186801|Clostridia,25YUG@186806|Eubacteriaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
NHEHCBFB_02821	1235802.C823_02103	1.12e-162	475.0	COG0641@1|root,COG0641@2|Bacteria,1V5NX@1239|Firmicutes,24GI8@186801|Clostridia	186801|Clostridia	C	Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
NHEHCBFB_02822	1235802.C823_02104	1.37e-165	488.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25UXT@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
NHEHCBFB_02829	596323.HMPREF0554_0754	2.06e-30	108.0	2E3EN@1|root,32YDN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
NHEHCBFB_02830	887325.HMPREF0381_0056	2.2e-28	105.0	2DQV8@1|root,338W7@2|Bacteria,1VJXI@1239|Firmicutes,25DTD@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
NHEHCBFB_02831	457412.RSAG_03506	5.81e-86	260.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3WJ00@541000|Ruminococcaceae	186801|Clostridia	L	transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
NHEHCBFB_02832	457412.RSAG_00897	4.57e-100	296.0	COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,24BEN@186801|Clostridia,3WM6R@541000|Ruminococcaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992,ko:K11051	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC2_membrane,ABC2_membrane_3
NHEHCBFB_02833	457412.RSAG_00896	0.0	1787.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TVCK@1239|Firmicutes,25KKE@186801|Clostridia,3WNVM@541000|Ruminococcaceae	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
NHEHCBFB_02834	457412.RSAG_00895	0.0	1795.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
NHEHCBFB_02835	457412.RSAG_00894	4.56e-47	155.0	COG2198@1|root,COG3437@1|root,COG2198@2|Bacteria,COG3437@2|Bacteria,1VG8R@1239|Firmicutes,24QS0@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
NHEHCBFB_02836	457412.RSAG_00893	3.27e-22	87.8	2C9RV@1|root,32WXH@2|Bacteria,1VCZ0@1239|Firmicutes,25AYI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02837	457412.RSAG_00892	2.73e-106	306.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,3WIK4@541000|Ruminococcaceae	186801|Clostridia	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
NHEHCBFB_02839	411469.EUBHAL_02436	6.8e-85	253.0	29H8K@1|root,30465@2|Bacteria,1V42R@1239|Firmicutes,24H9W@186801|Clostridia,25YFS@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02840	1408312.JNJS01000002_gene104	2.81e-146	418.0	2C83V@1|root,2Z99X@2|Bacteria,1TQYC@1239|Firmicutes,24E4W@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990,HTH_3
NHEHCBFB_02841	457421.CBFG_05938	6.81e-149	435.0	COG3950@1|root,COG3950@2|Bacteria,1UJJK@1239|Firmicutes,24CJD@186801|Clostridia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
NHEHCBFB_02842	1280698.AUJS01000061_gene1112	2.89e-104	306.0	COG1403@1|root,COG1403@2|Bacteria,1V5KT@1239|Firmicutes,24N2K@186801|Clostridia	186801|Clostridia	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02843	742765.HMPREF9457_00650	2.38e-50	159.0	2AD7W@1|root,312WU@2|Bacteria,1V7M4@1239|Firmicutes,24M52@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02844	397288.C806_04703	4.7e-174	501.0	COG0534@1|root,COG0534@2|Bacteria,1TQWU@1239|Firmicutes,24BZG@186801|Clostridia,27JMH@186928|unclassified Lachnospiraceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_02845	397288.C806_04702	1.33e-35	127.0	COG1846@1|root,COG1846@2|Bacteria,1VF1A@1239|Firmicutes,24SQT@186801|Clostridia,27PW5@186928|unclassified Lachnospiraceae	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
NHEHCBFB_02846	411470.RUMGNA_00823	6.32e-136	389.0	2DBGG@1|root,2Z94H@2|Bacteria,1V0JX@1239|Firmicutes,24CAV@186801|Clostridia,3Y11T@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02847	411459.RUMOBE_03477	0.0	946.0	COG2433@1|root,COG2433@2|Bacteria,1UI5D@1239|Firmicutes,25EHI@186801|Clostridia,3XZKG@572511|Blautia	186801|Clostridia	S	COG COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NHEHCBFB_02848	411459.RUMOBE_03478	8.39e-59	182.0	28NQR@1|root,2ZBQ4@2|Bacteria,1V3BU@1239|Firmicutes,24FVP@186801|Clostridia,3Y035@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02849	411459.RUMOBE_03479	9.51e-47	150.0	2DAN3@1|root,32TVS@2|Bacteria,1VABD@1239|Firmicutes,2598P@186801|Clostridia,3Y0GU@572511|Blautia	186801|Clostridia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NHEHCBFB_02850	411459.RUMOBE_03481	1.35e-239	663.0	COG0582@1|root,COG0582@2|Bacteria,1TSQW@1239|Firmicutes,249T6@186801|Clostridia,3XZQW@572511|Blautia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NHEHCBFB_02852	457412.RSAG_03327	2.12e-184	513.0	292MS@1|root,2ZQ5N@2|Bacteria,1VRQ1@1239|Firmicutes,24ZSR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02853	1121115.AXVN01000021_gene1680	7.68e-224	616.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia,3XZ0E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
NHEHCBFB_02854	1121115.AXVN01000021_gene1681	1.87e-307	838.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3XYK5@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
NHEHCBFB_02855	1121115.AXVN01000021_gene1682	1.11e-113	327.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,3XZYE@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
NHEHCBFB_02856	1121115.AXVN01000021_gene1683	1.77e-215	597.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3XZNQ@572511|Blautia	186801|Clostridia	K	chromosome partitioning protein	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
NHEHCBFB_02857	1121115.AXVN01000021_gene1684	1.32e-176	493.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3XYPE@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
NHEHCBFB_02858	1121115.AXVN01000021_gene1685	1.51e-233	642.0	COG0596@1|root,COG0596@2|Bacteria,1TR3M@1239|Firmicutes,24DR9@186801|Clostridia,3XYQ9@572511|Blautia	186801|Clostridia	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
NHEHCBFB_02859	457412.RSAG_02437	8.06e-92	268.0	COG0454@1|root,COG0456@2|Bacteria,1V239@1239|Firmicutes,24IE6@186801|Clostridia,3WKTE@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
NHEHCBFB_02860	457412.RSAG_04637	1.78e-42	139.0	2EA3V@1|root,3348U@2|Bacteria,1VFVI@1239|Firmicutes,24RVZ@186801|Clostridia,3WQVA@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02861	457412.RSAG_02439	2.6e-63	193.0	COG3041@1|root,COG3041@2|Bacteria,1TUTV@1239|Firmicutes,25NAT@186801|Clostridia,3WQD7@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial toxin of type II toxin-antitoxin system, YafQ	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
NHEHCBFB_02862	457412.RSAG_02440	1.54e-56	176.0	COG3077@1|root,COG3077@2|Bacteria,1VABY@1239|Firmicutes,24PQZ@186801|Clostridia,3WKWU@541000|Ruminococcaceae	186801|Clostridia	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
NHEHCBFB_02863	457412.RSAG_02441	7.52e-65	198.0	2EIVT@1|root,33CM3@2|Bacteria,1UKI7@1239|Firmicutes,25FXR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02864	1280698.AUJS01000042_gene3263	1.27e-99	289.0	COG1959@1|root,COG1959@2|Bacteria,1V34F@1239|Firmicutes,24H42@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NHEHCBFB_02865	457412.RSAG_02443	2.46e-219	604.0	COG0846@1|root,COG0846@2|Bacteria,1V192@1239|Firmicutes,24ERM@186801|Clostridia,3WIPW@541000|Ruminococcaceae	186801|Clostridia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02866	411459.RUMOBE_01480	1.11e-242	665.0	COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,247UN@186801|Clostridia,3XZV8@572511|Blautia	186801|Clostridia	K	COG COG0846 NAD-dependent protein deacetylases, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02867	1121115.AXVN01000089_gene2812	1.35e-102	297.0	COG1522@1|root,COG1522@2|Bacteria,1V1DR@1239|Firmicutes,25DYB@186801|Clostridia,3Y283@572511|Blautia	186801|Clostridia	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
NHEHCBFB_02868	1121115.AXVN01000089_gene2813	6.54e-308	841.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYX6@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	mepA_2	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_02869	1121115.AXVN01000043_gene3381	3.24e-56	177.0	2E53T@1|root,32ZWT@2|Bacteria,1VJS8@1239|Firmicutes,24S8H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02870	1423321.AS29_00720	3.89e-233	671.0	COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,1TUJU@1239|Firmicutes,4IF20@91061|Bacilli,1ZPEI@1386|Bacillus	91061|Bacilli	S	conserved protein (DUF2081)	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02871	585394.RHOM_04385	1.07e-90	267.0	2AYH2@1|root,31QKF@2|Bacteria,1V93C@1239|Firmicutes,24GEA@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4869)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4869
NHEHCBFB_02873	658655.HMPREF0988_01124	6.74e-86	254.0	2BFEN@1|root,32988@2|Bacteria,1V24H@1239|Firmicutes,24GVS@186801|Clostridia,27TR5@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4869)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4869
NHEHCBFB_02874	1280698.AUJS01000086_gene943	1.88e-183	516.0	28I6P@1|root,2Z89K@2|Bacteria,1TSZ7@1239|Firmicutes,24AUY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02875	1243664.CAVL020000039_gene618	3.85e-28	116.0	2FDGH@1|root,345I3@2|Bacteria,1VZV3@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02876	1121115.AXVN01000043_gene3382	1.45e-84	249.0	COG2461@1|root,COG2461@2|Bacteria,1V9ZF@1239|Firmicutes,24F8Y@186801|Clostridia	186801|Clostridia	S	Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02877	1121115.AXVN01000043_gene3383	5.75e-14	70.9	COG0300@1|root,COG0300@2|Bacteria,1UHN7@1239|Firmicutes,25FVQ@186801|Clostridia	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
NHEHCBFB_02878	1256908.HMPREF0373_01458	0.0	939.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25V53@186806|Eubacteriaceae	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
NHEHCBFB_02879	457412.RSAG_01324	2.55e-306	834.0	COG0675@1|root,COG0675@2|Bacteria,1TQAH@1239|Firmicutes,24EGY@186801|Clostridia	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
NHEHCBFB_02880	411459.RUMOBE_02187	3.98e-92	270.0	COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia,3Y0CK@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
NHEHCBFB_02881	411459.RUMOBE_01930	3.76e-127	362.0	COG3506@1|root,COG3506@2|Bacteria,1TSXY@1239|Firmicutes,2484H@186801|Clostridia	186801|Clostridia	F	Protein of unknown function (DUF1349)	-	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
NHEHCBFB_02882	658088.HMPREF0987_00288	6.91e-29	110.0	COG2267@1|root,COG2267@2|Bacteria,1TR25@1239|Firmicutes,24APA@186801|Clostridia,27NHN@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
NHEHCBFB_02883	657322.FPR_07260	1.32e-107	315.0	COG2267@1|root,COG2267@2|Bacteria,1TR25@1239|Firmicutes,24APA@186801|Clostridia,3WKUN@541000|Ruminococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
NHEHCBFB_02884	1280698.AUJS01000060_gene928	1.32e-123	352.0	COG0655@1|root,COG0655@2|Bacteria,1TSDE@1239|Firmicutes,24CNT@186801|Clostridia,27WEE@189330|Dorea	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NHEHCBFB_02885	457412.RSAG_01206	1.92e-152	430.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24C2K@186801|Clostridia,3WRJJ@541000|Ruminococcaceae	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NHEHCBFB_02886	1121115.AXVN01000001_gene1102	0.0	937.0	COG3290@1|root,COG5002@1|root,COG3290@2|Bacteria,COG5002@2|Bacteria,1VC62@1239|Firmicutes,25E8N@186801|Clostridia,3Y0QU@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NHEHCBFB_02887	1121115.AXVN01000001_gene1103	5.31e-312	876.0	2E7W1@1|root,332AT@2|Bacteria,1UYG9@1239|Firmicutes,24B0R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02888	1121115.AXVN01000001_gene1104	1.81e-307	840.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYPG@572511|Blautia	186801|Clostridia	V	COG COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_02889	1121115.AXVN01000001_gene1105	3.15e-38	127.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3Y0IR@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
NHEHCBFB_02890	457412.RSAG_01211	5.93e-124	353.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,3WJHK@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
NHEHCBFB_02891	457412.RSAG_01212	4.23e-306	834.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
NHEHCBFB_02892	457412.RSAG_01213	1.34e-232	641.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,3WGX7@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Phosphate acetyl butaryl transferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
NHEHCBFB_02893	457412.RSAG_04661	2.83e-280	771.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,3WI9X@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
NHEHCBFB_02894	1121115.AXVN01000001_gene1110	1.09e-178	498.0	COG2865@1|root,COG2865@2|Bacteria,1TQXE@1239|Firmicutes,249ND@186801|Clostridia,3XZUK@572511|Blautia	186801|Clostridia	K	COG NOG11764 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02895	1121115.AXVN01000001_gene1111	1.24e-84	250.0	COG1340@1|root,COG1340@2|Bacteria,1V7S0@1239|Firmicutes,24KZW@186801|Clostridia	186801|Clostridia	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
NHEHCBFB_02896	457412.RSAG_01218	5.84e-92	271.0	2CJ2H@1|root,33QUA@2|Bacteria,1VSMM@1239|Firmicutes,24Z9D@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
NHEHCBFB_02897	457412.RSAG_01219	2.71e-297	812.0	COG0038@1|root,COG0038@2|Bacteria,1UZ4F@1239|Firmicutes,24921@186801|Clostridia	186801|Clostridia	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
NHEHCBFB_02898	1121115.AXVN01000001_gene1114	6.37e-188	522.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3Y16A@572511|Blautia	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
NHEHCBFB_02899	457412.RSAG_01221	1.04e-199	555.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3WGQG@541000|Ruminococcaceae	186801|Clostridia	P	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
NHEHCBFB_02900	1121115.AXVN01000001_gene1116	3.29e-235	648.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3XZPA@572511|Blautia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
NHEHCBFB_02901	1121115.AXVN01000001_gene1117	6.19e-263	720.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,3XYRN@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisC	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
NHEHCBFB_02902	457412.RSAG_01224	0.0	870.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,3WGZM@541000|Ruminococcaceae	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
NHEHCBFB_02903	1121115.AXVN01000001_gene1119	3.78e-57	177.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,3Y0FS@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
NHEHCBFB_02904	1121115.AXVN01000001_gene1120	3.06e-195	540.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,3XYGN@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
NHEHCBFB_02905	1121115.AXVN01000001_gene1121	5.75e-141	398.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,3Y05Z@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
NHEHCBFB_02906	1121115.AXVN01000001_gene1122	0.0	1790.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3XYYX@572511|Blautia	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
NHEHCBFB_02907	1121115.AXVN01000001_gene1123	1.61e-73	221.0	2ETPV@1|root,33M7I@2|Bacteria,1VNHF@1239|Firmicutes,25A5M@186801|Clostridia,3Y0Q4@572511|Blautia	186801|Clostridia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
NHEHCBFB_02908	457412.RSAG_01230	0.0	1222.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3WG9V@541000|Ruminococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NHEHCBFB_02910	457412.RSAG_01231	9.59e-196	549.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	FMN_bind,Flg_new,LRR_5
NHEHCBFB_02911	457412.RSAG_01232	0.0	910.0	COG0584@1|root,COG0584@2|Bacteria,1VB6Y@1239|Firmicutes,24KSW@186801|Clostridia	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,GDPD
NHEHCBFB_02912	1121115.AXVN01000001_gene1127	7.16e-51	160.0	2FADH@1|root,342MV@2|Bacteria,1VXR1@1239|Firmicutes,252AC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02913	1121115.AXVN01000001_gene1128	0.0	880.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,3XZ9R@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
NHEHCBFB_02914	1121115.AXVN01000001_gene1129	5.11e-208	575.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,3XYV8@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
NHEHCBFB_02915	457412.RSAG_04660	1.45e-181	510.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia,3WGVT@541000|Ruminococcaceae	186801|Clostridia	P	Mg2 transporter protein CorA family protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
NHEHCBFB_02916	457412.RSAG_01238	5.27e-260	712.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,3WG94@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
NHEHCBFB_02917	1121115.AXVN01000001_gene1132	1.71e-265	726.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,248JF@186801|Clostridia,3XZ28@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
NHEHCBFB_02918	1121115.AXVN01000001_gene1133	1.54e-308	840.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3XZ92@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NHEHCBFB_02919	457412.RSAG_01241	6.92e-235	646.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,3WGUW@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
NHEHCBFB_02920	1121115.AXVN01000001_gene1135	0.0	967.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,3XZE7@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
NHEHCBFB_02921	457412.RSAG_01243	2.74e-212	587.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,2494Z@186801|Clostridia,3WG89@541000|Ruminococcaceae	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
NHEHCBFB_02922	1121115.AXVN01000001_gene1137	6.25e-112	322.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,3Y08Y@572511|Blautia	186801|Clostridia	H	precorrin-2 oxidase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
NHEHCBFB_02923	1121115.AXVN01000001_gene1138	1.94e-294	804.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3XZQJ@572511|Blautia	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,NAD_binding_7,Shikimate_DH
NHEHCBFB_02924	457412.RSAG_01246	2.48e-92	285.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3WGP1@541000|Ruminococcaceae	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NHEHCBFB_02926	1121115.AXVN01000001_gene1140	1.61e-183	511.0	2DEAV@1|root,2ZM6Y@2|Bacteria,1V2HI@1239|Firmicutes,24GNN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02927	457412.RSAG_01249	2.69e-165	462.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia,3WHY5@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulatory protein KdpE	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_02928	457412.RSAG_01250	0.0	986.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia,3WG8P@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD
NHEHCBFB_02929	457412.RSAG_01251	1.34e-151	426.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,3WGAG@541000|Ruminococcaceae	186801|Clostridia	C	system potassium uptake protein	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NHEHCBFB_02930	457412.RSAG_01252	6.05e-307	838.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3WGPB@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NHEHCBFB_02931	518637.EUBIFOR_02175	3.96e-45	145.0	2EMT3@1|root,33FFH@2|Bacteria,1VMD0@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02932	518637.EUBIFOR_00777	6.7e-64	198.0	2DKVF@1|root,30GMW@2|Bacteria,1V8RI@1239|Firmicutes,3VUR2@526524|Erysipelotrichia	1239|Firmicutes	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
NHEHCBFB_02933	518637.EUBIFOR_00778	1.17e-46	149.0	2EIQY@1|root,33CGC@2|Bacteria,1VN28@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
NHEHCBFB_02934	411462.DORLON_01116	2.35e-96	281.0	2BQ4M@1|root,32IZ0@2|Bacteria,1V6N2@1239|Firmicutes,24KA6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
NHEHCBFB_02935	411462.DORLON_01117	2.9e-40	133.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QPB@186801|Clostridia,27VUC@189330|Dorea	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NHEHCBFB_02936	411462.DORLON_00193	3.2e-67	204.0	2C5R4@1|root,30S72@2|Bacteria,1V578@1239|Firmicutes,24IJT@186801|Clostridia,27WRP@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NHEHCBFB_02937	1297617.JPJD01000080_gene1402	1.95e-34	130.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,26A8R@186813|unclassified Clostridiales	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,T4SS-DNA_transf,Zn_ribbon_recom
NHEHCBFB_02939	457412.RSAG_01271	6.2e-241	662.0	COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,24HIG@186801|Clostridia,3WMAG@541000|Ruminococcaceae	186801|Clostridia	S	SdpI/YhfL protein family	sdpI	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
NHEHCBFB_02940	1121115.AXVN01000001_gene1146	5.03e-67	203.0	COG0640@1|root,COG0640@2|Bacteria,1VA3M@1239|Firmicutes,24NEC@186801|Clostridia,3Y0CY@572511|Blautia	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	czrA	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
NHEHCBFB_02941	1121115.AXVN01000001_gene1147	9.57e-145	407.0	COG0731@1|root,COG0731@2|Bacteria,1UJ6S@1239|Firmicutes,25EWY@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
NHEHCBFB_02942	457412.RSAG_01274	1.49e-114	329.0	COG4720@1|root,COG4720@2|Bacteria,1V8B5@1239|Firmicutes,24J8T@186801|Clostridia,3WJ8C@541000|Ruminococcaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
NHEHCBFB_02943	1121115.AXVN01000001_gene1149	1.92e-206	571.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,24ABV@186801|Clostridia,3XZZQ@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
NHEHCBFB_02944	457412.RSAG_01276	8.29e-311	847.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,3WHQS@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
NHEHCBFB_02945	1121115.AXVN01000001_gene1151	1.34e-146	413.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,24B9Z@186801|Clostridia,3XZ03@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
NHEHCBFB_02946	457412.RSAG_01278	0.0	971.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,248XW@186801|Clostridia,3WHB7@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15780	AAA_26,CbiA,GATase_3
NHEHCBFB_02947	457412.RSAG_01279	8.31e-253	693.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,3WHN4@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
NHEHCBFB_02948	457412.RSAG_01280	8.29e-226	623.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia,3WGT1@541000|Ruminococcaceae	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
NHEHCBFB_02949	457412.RSAG_01281	0.0	927.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,3WH17@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
NHEHCBFB_02950	1121115.AXVN01000001_gene1156	0.0	1325.0	COG2099@1|root,COG2241@1|root,COG2242@1|root,COG2099@2|Bacteria,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,3XYK0@572511|Blautia	186801|Clostridia	H	precorrin-6B methylase decarboxylase cbiT cbiE	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
NHEHCBFB_02951	1121115.AXVN01000001_gene1157	2.31e-175	488.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,3XZR9@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NHEHCBFB_02952	1121115.AXVN01000001_gene1158	2.34e-263	722.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,3XZ11@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
NHEHCBFB_02953	457412.RSAG_01285	8.69e-183	508.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia,3WH3H@541000|Ruminococcaceae	186801|Clostridia	H	precorrin-4 C11-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NHEHCBFB_02954	1121115.AXVN01000001_gene1160	9.3e-272	744.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,3XYN5@572511|Blautia	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
NHEHCBFB_02955	457412.RSAG_01287	3.01e-308	842.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3WHZE@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_02956	457412.RSAG_01288	1.42e-213	590.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,3WI75@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NHEHCBFB_02957	1121115.AXVN01000001_gene1163	1.27e-173	485.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,3XZ5H@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
NHEHCBFB_02958	457412.RSAG_01290	2.17e-285	780.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,3WGXA@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
NHEHCBFB_02959	457412.RSAG_01291	6.57e-136	384.0	COG2519@1|root,COG2519@2|Bacteria,1V6VU@1239|Firmicutes,24JEE@186801|Clostridia,3WIXW@541000|Ruminococcaceae	186801|Clostridia	J	Putative rRNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
NHEHCBFB_02960	457412.RSAG_01292	2.14e-158	448.0	COG0652@1|root,COG0652@2|Bacteria,1V1SP@1239|Firmicutes,24G4H@186801|Clostridia,3WS4C@541000|Ruminococcaceae	186801|Clostridia	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
NHEHCBFB_02961	1121115.AXVN01000001_gene1167	4.2e-115	330.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,3XZVQ@572511|Blautia	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
NHEHCBFB_02962	1121115.AXVN01000001_gene1168	1.35e-75	229.0	COG3103@1|root,COG3103@2|Bacteria,1UHDJ@1239|Firmicutes,25Q4A@186801|Clostridia,3Y0IP@572511|Blautia	186801|Clostridia	T	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
NHEHCBFB_02963	457412.RSAG_01296	1.03e-238	656.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia	186801|Clostridia	O	XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
NHEHCBFB_02964	457412.RSAG_01297	1.27e-273	750.0	COG1301@1|root,COG1301@2|Bacteria,1TP4N@1239|Firmicutes,2494N@186801|Clostridia,3WHRD@541000|Ruminococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
NHEHCBFB_02965	1121115.AXVN01000001_gene1171	4.71e-142	401.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,3Y06N@572511|Blautia	186801|Clostridia	O	COG NOG13230 non supervised orthologous group	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
NHEHCBFB_02966	1121115.AXVN01000001_gene1172	0.0	920.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,3XZ6S@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
NHEHCBFB_02967	457412.RSAG_01300	1.07e-150	423.0	COG2964@1|root,COG2964@2|Bacteria,1TSI2@1239|Firmicutes,249X6@186801|Clostridia,3WM7H@541000|Ruminococcaceae	186801|Clostridia	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
NHEHCBFB_02968	457412.RSAG_01301	1.4e-298	815.0	COG3290@1|root,COG3290@2|Bacteria,1TS6E@1239|Firmicutes,24DDI@186801|Clostridia,3WS78@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NHEHCBFB_02969	457412.RSAG_01302	8.45e-168	471.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,3WJ2Q@541000|Ruminococcaceae	186801|Clostridia	T	LytTr DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NHEHCBFB_02970	1121115.AXVN01000001_gene1176	5.14e-42	137.0	2FI33@1|root,349VV@2|Bacteria,1VYV4@1239|Firmicutes,253ZQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02971	457412.RSAG_01304	2.71e-120	343.0	2C2RJ@1|root,33VFU@2|Bacteria,1VV8Z@1239|Firmicutes,250DV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02972	1121115.AXVN01000170_gene502	9.63e-248	679.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3XYWE@572511|Blautia	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
NHEHCBFB_02973	1121115.AXVN01000170_gene503	5.14e-111	319.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,3Y022@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
NHEHCBFB_02974	457412.RSAG_04656	4.65e-256	701.0	COG2365@1|root,COG2365@2|Bacteria,1V639@1239|Firmicutes,25CGQ@186801|Clostridia	186801|Clostridia	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
NHEHCBFB_02975	457412.RSAG_01309	7.01e-217	599.0	COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes,24AQF@186801|Clostridia,3WI18@541000|Ruminococcaceae	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NHEHCBFB_02976	457412.RSAG_01310	1.25e-201	557.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,25B6S@186801|Clostridia,3WKHA@541000|Ruminococcaceae	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NHEHCBFB_02977	457412.RSAG_01311	6.04e-309	841.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia,3WH7R@541000|Ruminococcaceae	186801|Clostridia	E	M18 family aminopeptidase	apeB	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
NHEHCBFB_02978	1121115.AXVN01000114_gene1675	1.45e-76	228.0	COG1917@1|root,COG1917@2|Bacteria,1VGJQ@1239|Firmicutes,25EGC@186801|Clostridia,3Y09F@572511|Blautia	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NHEHCBFB_02979	457412.RSAG_01313	1.16e-204	566.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,3WI4F@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
NHEHCBFB_02980	457412.RSAG_01314	3.18e-195	541.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,3WHB5@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
NHEHCBFB_02981	457412.RSAG_01315	1.48e-119	341.0	COG1418@1|root,COG1418@2|Bacteria,1VBWP@1239|Firmicutes,24JJV@186801|Clostridia,3WJVP@541000|Ruminococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
NHEHCBFB_02982	457412.RSAG_01316	5e-130	369.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,3WIA5@541000|Ruminococcaceae	186801|Clostridia	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
NHEHCBFB_02983	1121115.AXVN01000114_gene1670	1.03e-92	271.0	2DMPJ@1|root,32SWG@2|Bacteria,1V7RA@1239|Firmicutes,24NGU@186801|Clostridia,3Y0C1@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02984	1121115.AXVN01000114_gene1669	0.0	975.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,248FH@186801|Clostridia,3XZ9Z@572511|Blautia	186801|Clostridia	L	COG COG0389 Nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
NHEHCBFB_02985	457412.RSAG_01321	2.72e-97	283.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,24HPW@186801|Clostridia,3WJRQ@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
NHEHCBFB_02986	457412.RSAG_01322	2.27e-82	243.0	COG0346@1|root,COG0346@2|Bacteria,1V1Y9@1239|Firmicutes,24FQQ@186801|Clostridia,3WJC5@541000|Ruminococcaceae	186801|Clostridia	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
NHEHCBFB_02987	411459.RUMOBE_01951	1.16e-93	273.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,3Y01F@572511|Blautia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
NHEHCBFB_02988	1410626.JHXB01000008_gene1187	1.24e-46	152.0	2CABA@1|root,32ZBQ@2|Bacteria,1VFWB@1239|Firmicutes,24RY5@186801|Clostridia,27Q1N@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02989	457412.RSAG_01326	1.21e-90	265.0	COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,24HBX@186801|Clostridia,3WJAK@541000|Ruminococcaceae	186801|Clostridia	T	low molecular weight	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
NHEHCBFB_02990	411469.EUBHAL_02584	3.41e-165	461.0	COG0500@1|root,COG2226@2|Bacteria,1TT7G@1239|Firmicutes,24E44@186801|Clostridia,25WM2@186806|Eubacteriaceae	186801|Clostridia	Q	NOG31153 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02991	1256908.HMPREF0373_00330	1.48e-42	140.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,24QZK@186801|Clostridia,25XAB@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
NHEHCBFB_02992	457412.RSAG_01328	1.37e-45	147.0	2EIT0@1|root,33CIB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02993	457412.RSAG_01329	3.91e-91	266.0	COG0494@1|root,COG0494@2|Bacteria,1V6ET@1239|Firmicutes,25EBI@186801|Clostridia,3WISB@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
NHEHCBFB_02994	457412.RSAG_01331	0.0	2073.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,3WHD8@541000|Ruminococcaceae	186801|Clostridia	L	helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
NHEHCBFB_02995	1121115.AXVN01000097_gene3800	3e-86	253.0	COG3304@1|root,COG3304@2|Bacteria,1VADH@1239|Firmicutes,24NFV@186801|Clostridia,3Y0CX@572511|Blautia	186801|Clostridia	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
NHEHCBFB_02996	411459.RUMOBE_01935	1.3e-40	134.0	2BCQI@1|root,326AY@2|Bacteria,1US91@1239|Firmicutes,25A84@186801|Clostridia,3Y22C@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_02997	622312.ROSEINA2194_03252	1e-90	267.0	COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,24MB0@186801|Clostridia	186801|Clostridia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
NHEHCBFB_02998	457412.RSAG_04653	0.0	886.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24CRM@186801|Clostridia,3WS41@541000|Ruminococcaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
NHEHCBFB_02999	457412.RSAG_03523	2.36e-105	303.0	COG1943@1|root,COG1943@2|Bacteria,1VAIQ@1239|Firmicutes,24IPG@186801|Clostridia,3WRVG@541000|Ruminococcaceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
NHEHCBFB_03000	457412.RSAG_01337	2.19e-292	797.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,247ZX@186801|Clostridia,3WGAI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
NHEHCBFB_03001	1121115.AXVN01000187_gene1813	9.77e-34	115.0	2EI8P@1|root,332BW@2|Bacteria,1VFSF@1239|Firmicutes,24RRY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03002	1121115.AXVN01000041_gene2601	3.71e-303	825.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,3XYT4@572511|Blautia	186801|Clostridia	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NHEHCBFB_03003	1121115.AXVN01000041_gene2600	0.0	942.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,3XYZ1@572511|Blautia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
NHEHCBFB_03004	1121115.AXVN01000041_gene2599	0.0	937.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,3XZNT@572511|Blautia	186801|Clostridia	H	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
NHEHCBFB_03005	1121115.AXVN01000041_gene2598	4.25e-55	172.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,3Y0HE@572511|Blautia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
NHEHCBFB_03006	1121115.AXVN01000041_gene2597	0.0	889.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia,3XZ7F@572511|Blautia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
NHEHCBFB_03007	457412.RSAG_01344	3.1e-119	342.0	COG3707@1|root,COG3707@2|Bacteria,1V2S1@1239|Firmicutes,24EWG@186801|Clostridia,3WK4K@541000|Ruminococcaceae	186801|Clostridia	K	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR
NHEHCBFB_03008	1121115.AXVN01000041_gene2595	0.0	889.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,3XYYT@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
NHEHCBFB_03009	1121115.AXVN01000041_gene2593	7.19e-23	91.7	2CM8T@1|root,32SE0@2|Bacteria,1VBP1@1239|Firmicutes,24Q65@186801|Clostridia	186801|Clostridia	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
NHEHCBFB_03010	457412.RSAG_04694	3.45e-176	500.0	COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,249JM@186801|Clostridia,3WRT5@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
NHEHCBFB_03011	1232447.BAHW02000027_gene2078	7.62e-202	561.0	COG2207@1|root,COG2207@2|Bacteria,1TSFI@1239|Firmicutes,249B8@186801|Clostridia,26AYS@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
NHEHCBFB_03012	1235802.C823_00599	6.94e-68	219.0	COG3385@1|root,COG3385@2|Bacteria,1TRKC@1239|Firmicutes,24EUB@186801|Clostridia	186801|Clostridia	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
NHEHCBFB_03013	411459.RUMOBE_03500	5.93e-208	576.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3Y16Y@572511|Blautia	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
NHEHCBFB_03014	411461.DORFOR_00178	2.83e-69	209.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes	1239|Firmicutes	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NHEHCBFB_03015	1280698.AUJS01000017_gene1835	5.83e-176	491.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia,27WUJ@189330|Dorea	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
NHEHCBFB_03016	457412.RSAG_03416	6.37e-152	427.0	COG0664@1|root,COG0664@2|Bacteria,1V2MV@1239|Firmicutes,24B7K@186801|Clostridia,3WISN@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
NHEHCBFB_03017	411459.RUMOBE_03497	0.0	1098.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,3XZ97@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 9.98	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
NHEHCBFB_03018	1280698.AUJS01000017_gene1829	4.54e-70	211.0	COG0607@1|root,COG0607@2|Bacteria,1UX61@1239|Firmicutes,25KW5@186801|Clostridia,27X0I@189330|Dorea	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
NHEHCBFB_03019	411459.RUMOBE_03495	1.57e-61	189.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3Y0FX@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NHEHCBFB_03020	411459.RUMOBE_03494	4.77e-166	465.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,25073@186801|Clostridia,3XYII@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	baiA	-	1.1.1.100,1.1.1.159	ko:K00059,ko:K00076	ko00061,ko00121,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00121,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
NHEHCBFB_03021	1280698.AUJS01000054_gene1478	3.57e-36	121.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,27X1Z@189330|Dorea	186801|Clostridia	C	Rubredoxin	rd	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Rubredoxin
NHEHCBFB_03023	457412.RSAG_01908	0.0	1001.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3WIB4@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
NHEHCBFB_03024	457412.RSAG_01909	0.0	1163.0	COG1263@1|root,COG2190@1|root,COG1263@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,3WG8J@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	2.7.1.211	ko:K02756,ko:K02757,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269,M00271	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
NHEHCBFB_03025	457412.RSAG_01910	1.24e-199	553.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,24931@186801|Clostridia,3WIEJ@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	licT	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
NHEHCBFB_03026	1280671.AUJH01000028_gene895	6.15e-41	137.0	2CU1H@1|root,32SUI@2|Bacteria,1VB8S@1239|Firmicutes,24PZC@186801|Clostridia,4C0G3@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03027	742765.HMPREF9457_01634	1.02e-215	598.0	COG1266@1|root,COG1266@2|Bacteria,1UYS2@1239|Firmicutes,24BKW@186801|Clostridia,27X9E@189330|Dorea	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
NHEHCBFB_03028	471875.RUMLAC_01723	3.42e-12	67.0	COG1598@1|root,COG1598@2|Bacteria,1VAKM@1239|Firmicutes,24K5X@186801|Clostridia,3WKAK@541000|Ruminococcaceae	186801|Clostridia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB_lk_antitox
NHEHCBFB_03029	1235798.C817_05519	1.22e-66	219.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,27W8J@189330|Dorea	186801|Clostridia	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
NHEHCBFB_03030	1235800.C819_04093	1.71e-78	234.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24I83@186801|Clostridia,27N00@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, gntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
NHEHCBFB_03031	1235800.C819_04094	4.78e-188	524.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,27IKW@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NHEHCBFB_03032	1235800.C819_04095	6.4e-122	350.0	2DPZV@1|root,3344W@2|Bacteria,1VJXN@1239|Firmicutes,24RIB@186801|Clostridia,27KT8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
NHEHCBFB_03034	1121115.AXVN01000109_gene2346	5.69e-111	320.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,3Y07W@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
NHEHCBFB_03035	411459.RUMOBE_01921	4.63e-63	193.0	COG0662@1|root,COG0662@2|Bacteria,1V7HI@1239|Firmicutes,24JQZ@186801|Clostridia	186801|Clostridia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NHEHCBFB_03038	1121115.AXVN01000078_gene2834	2.74e-195	544.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,3XYRQ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
NHEHCBFB_03041	457412.RSAG_01901	6.66e-72	218.0	COG3943@1|root,COG3943@2|Bacteria,1TPH4@1239|Firmicutes,248NI@186801|Clostridia,3WHBJ@541000|Ruminococcaceae	186801|Clostridia	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
NHEHCBFB_03042	457412.RSAG_01903	6.56e-131	371.0	COG1443@1|root,COG1443@2|Bacteria,1V6SB@1239|Firmicutes,24HX1@186801|Clostridia,3WK9W@541000|Ruminococcaceae	186801|Clostridia	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
NHEHCBFB_03043	457412.RSAG_01904	4.4e-117	335.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia,3WK3U@541000|Ruminococcaceae	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NHEHCBFB_03044	411459.RUMOBE_03759	1.69e-17	78.2	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3Y0EM@572511|Blautia	186801|Clostridia	K	COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NHEHCBFB_03046	411459.RUMOBE_01935	6.48e-32	112.0	2BCQI@1|root,326AY@2|Bacteria,1US91@1239|Firmicutes,25A84@186801|Clostridia,3Y22C@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03048	457412.RSAG_00901	1.2e-46	154.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia,3WJ1H@541000|Ruminococcaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NHEHCBFB_03049	457412.RSAG_00900	0.0	1184.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3WSRM@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
NHEHCBFB_03050	877414.ATWA01000038_gene1524	2.37e-22	94.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,2682D@186813|unclassified Clostridiales	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	-	-	-	-	-	-	-	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
NHEHCBFB_03051	500632.CLONEX_00763	2.62e-33	114.0	COG3177@1|root,COG3177@2|Bacteria,1VISE@1239|Firmicutes,24R8K@186801|Clostridia	186801|Clostridia	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03052	585394.RHOM_13765	1.46e-302	825.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,249UX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
NHEHCBFB_03053	518637.EUBIFOR_00728	3.77e-36	122.0	COG3311@1|root,COG3311@2|Bacteria,1V8AE@1239|Firmicutes,3VU5J@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NHEHCBFB_03054	411459.RUMOBE_02159	6.19e-38	138.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3Y03I@572511|Blautia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
NHEHCBFB_03055	457412.RSAG_00865	6.05e-98	285.0	COG1846@1|root,COG1846@2|Bacteria,1V8KT@1239|Firmicutes,24B99@186801|Clostridia,3WGSA@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulators	mgrA	-	-	-	-	-	-	-	-	-	-	-	MarR
NHEHCBFB_03056	1280698.AUJS01000042_gene3266	1.58e-175	488.0	COG4422@1|root,COG4422@2|Bacteria,1TPRY@1239|Firmicutes,247VT@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
NHEHCBFB_03057	457412.RSAG_00863	7.14e-229	629.0	COG1533@1|root,COG1533@2|Bacteria,1TRIS@1239|Firmicutes,25CEW@186801|Clostridia,3WGZD@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NHEHCBFB_03058	411469.EUBHAL_01633	2.56e-99	288.0	COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,25B3D@186801|Clostridia,25WSQ@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NHEHCBFB_03059	411469.EUBHAL_01634	1.85e-238	656.0	COG1073@1|root,COG1073@2|Bacteria,1TPW7@1239|Firmicutes,24A5B@186801|Clostridia,25VKG@186806|Eubacteriaceae	186801|Clostridia	S	Dienelactone hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,DLH,Peptidase_S15
NHEHCBFB_03060	1410674.JNKU01000036_gene435	4.29e-99	290.0	COG0655@1|root,COG0655@2|Bacteria,1V26K@1239|Firmicutes	1239|Firmicutes	S	Nadph-dependent fmn reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NHEHCBFB_03061	665950.HMPREF1025_02919	0.0	1005.0	COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,251Y5@186801|Clostridia,27UCA@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
NHEHCBFB_03062	665950.HMPREF1025_02918	4.77e-77	229.0	COG3436@1|root,COG3436@2|Bacteria,1V7U9@1239|Firmicutes,24K4W@186801|Clostridia,27P7R@186928|unclassified Lachnospiraceae	186801|Clostridia	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
NHEHCBFB_03063	665950.HMPREF1025_02917	4.02e-95	277.0	28IAH@1|root,2Z8D3@2|Bacteria,1TRGI@1239|Firmicutes,24U6D@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03064	1235798.C817_00872	1.61e-45	155.0	COG0789@1|root,COG0789@2|Bacteria,1V37U@1239|Firmicutes,25AZY@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
NHEHCBFB_03065	515620.EUBELI_20098	4.49e-180	512.0	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia,25WUW@186806|Eubacteriaceae	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
NHEHCBFB_03066	515620.EUBELI_20098	4.64e-20	88.2	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia,25WUW@186806|Eubacteriaceae	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
NHEHCBFB_03067	1280698.AUJS01000042_gene3272	4.32e-100	296.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
NHEHCBFB_03068	483218.BACPEC_02561	2.63e-205	567.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,26AN9@186813|unclassified Clostridiales	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
NHEHCBFB_03069	1235802.C823_01098	4.3e-259	712.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,25YB7@186806|Eubacteriaceae	186801|Clostridia	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
NHEHCBFB_03071	694427.Palpr_1134	8.33e-19	87.8	COG3594@1|root,COG3594@2|Bacteria,4NYWW@976|Bacteroidetes,2FU17@200643|Bacteroidia	976|Bacteroidetes	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NHEHCBFB_03072	484770.UFO1_4152	1.99e-114	350.0	COG2244@1|root,COG2244@2|Bacteria,1TS41@1239|Firmicutes	1239|Firmicutes	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	MatE,Polysacc_synt
NHEHCBFB_03074	985255.APHJ01000021_gene1345	4.39e-34	132.0	2DMF5@1|root,32UGW@2|Bacteria,4P0ZX@976|Bacteroidetes,1I8FA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03075	547042.BACCOPRO_00719	6.24e-11	71.6	2EI0T@1|root,33BSA@2|Bacteria,4PJQK@976|Bacteroidetes,2FSPF@200643|Bacteroidia,4AR4Z@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
NHEHCBFB_03076	1170562.Cal6303_3098	1.32e-54	185.0	COG1216@1|root,COG1216@2|Bacteria,1GQ7U@1117|Cyanobacteria,1HTNI@1161|Nostocales	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NHEHCBFB_03077	1226325.HMPREF1548_04603	9.41e-56	195.0	COG0438@1|root,COG0438@2|Bacteria,1VUPS@1239|Firmicutes,250JC@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03078	1458462.JNLK01000001_gene287	9.04e-26	100.0	COG1143@1|root,COG1143@2|Bacteria,1VKVR@1239|Firmicutes,25IVH@186801|Clostridia,27STK@186928|unclassified Lachnospiraceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03079	1280680.AUJU01000009_gene15	1.68e-68	223.0	COG1035@1|root,COG1035@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia,4BZCS@830|Butyrivibrio	186801|Clostridia	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N
NHEHCBFB_03080	1415775.U729_522	1.06e-108	330.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia,36IK4@31979|Clostridiaceae	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
NHEHCBFB_03081	546271.Selsp_0051	1.02e-37	145.0	COG2327@1|root,COG2327@2|Bacteria,1V2B8@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
NHEHCBFB_03082	457412.RSAG_01022	9e-146	423.0	COG0438@1|root,COG0438@2|Bacteria,1V5R1@1239|Firmicutes,24GWF@186801|Clostridia,3WM1T@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
NHEHCBFB_03083	1506994.JNLQ01000002_gene1420	1.56e-65	217.0	COG1835@1|root,COG1835@2|Bacteria,1UR35@1239|Firmicutes,258WQ@186801|Clostridia,4BWHM@830|Butyrivibrio	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NHEHCBFB_03084	457412.RSAG_01023	4.88e-149	423.0	COG1922@1|root,COG1922@2|Bacteria,1UIHR@1239|Firmicutes,25BDH@186801|Clostridia,3WS61@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	CoA_binding_3,Glyco_tran_WecB
NHEHCBFB_03085	748224.HMPREF9436_02567	1.44e-159	461.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,3WGZG@541000|Ruminococcaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
NHEHCBFB_03087	457412.RSAG_01024	0.0	950.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia,3WHG7@541000|Ruminococcaceae	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
NHEHCBFB_03088	1121115.AXVN01000044_gene2027	4.58e-76	231.0	COG0250@1|root,COG0250@2|Bacteria,1V3BF@1239|Firmicutes,24G49@186801|Clostridia	186801|Clostridia	K	Transcription termination	-	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
NHEHCBFB_03089	457412.RSAG_01026	8.36e-138	390.0	2EB5C@1|root,335VY@2|Bacteria,1VI1F@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03090	457412.RSAG_01027	8.02e-217	602.0	COG1316@1|root,COG1316@2|Bacteria,1UY3P@1239|Firmicutes,24H37@186801|Clostridia,3WJFR@541000|Ruminococcaceae	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
NHEHCBFB_03091	457412.RSAG_01028	8.91e-191	534.0	2E1XM@1|root,32X6K@2|Bacteria,1VCEM@1239|Firmicutes,24NS0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03092	457412.RSAG_04680	3.14e-165	462.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,3WI2V@541000|Ruminococcaceae	186801|Clostridia	D	Capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
NHEHCBFB_03093	457412.RSAG_01029	1.35e-166	468.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24G4J@186801|Clostridia,3WRUK@541000|Ruminococcaceae	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
NHEHCBFB_03094	457412.RSAG_01030	1.91e-181	504.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia,3WK04@541000|Ruminococcaceae	186801|Clostridia	GM	capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
NHEHCBFB_03095	457412.RSAG_01031	1.48e-247	681.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3WGII@541000|Ruminococcaceae	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
NHEHCBFB_03096	1121115.AXVN01000019_gene162	4.56e-211	583.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,25E67@186801|Clostridia,3XYNX@572511|Blautia	186801|Clostridia	C	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
NHEHCBFB_03097	1121115.AXVN01000019_gene163	6.27e-145	410.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3XZMG@572511|Blautia	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
NHEHCBFB_03098	457412.RSAG_01033	0.0	865.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,3WGDB@541000|Ruminococcaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
NHEHCBFB_03099	457412.RSAG_01034	0.0	924.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate carboxylase, C-terminal domain subunit K01960	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
NHEHCBFB_03100	1121115.AXVN01000019_gene166	3.46e-265	727.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia,3XZ7I@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
NHEHCBFB_03101	1121115.AXVN01000019_gene167	7.37e-54	171.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
NHEHCBFB_03102	457412.RSAG_01037	2.66e-129	372.0	2DMIV@1|root,32RW6@2|Bacteria,1VAMW@1239|Firmicutes,24DVC@186801|Clostridia,3WJXG@541000|Ruminococcaceae	186801|Clostridia	C	Oxaloacetate decarboxylase, gamma chain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3887,OAD_gamma
NHEHCBFB_03103	457412.RSAG_01038	0.0	920.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae	186801|Clostridia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
NHEHCBFB_03104	457412.RSAG_01040	0.0	1327.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WJT6@541000|Ruminococcaceae	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NHEHCBFB_03105	457412.RSAG_01041	3.75e-210	580.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WGF4@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
NHEHCBFB_03106	457412.RSAG_01042	2.18e-169	474.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,3WIPP@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
NHEHCBFB_03107	457412.RSAG_01054	0.0	871.0	COG0659@1|root,COG0659@2|Bacteria,1TT9Y@1239|Firmicutes,249RX@186801|Clostridia,3WSRN@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	BenE
NHEHCBFB_03108	457412.RSAG_01055	1.88e-273	749.0	COG0477@1|root,COG0477@2|Bacteria,1TS50@1239|Firmicutes,24BE2@186801|Clostridia,3WKIP@541000|Ruminococcaceae	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NHEHCBFB_03109	457412.RSAG_01056	8.47e-208	575.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WI65@541000|Ruminococcaceae	186801|Clostridia	C	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
NHEHCBFB_03110	457412.RSAG_01057	0.0	1268.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WH0G@541000|Ruminococcaceae	186801|Clostridia	C	NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NHEHCBFB_03111	457412.RSAG_01058	1.36e-206	570.0	COG1082@1|root,COG1082@2|Bacteria,1TT50@1239|Firmicutes,248RM@186801|Clostridia,3WN3B@541000|Ruminococcaceae	186801|Clostridia	L	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NHEHCBFB_03112	457412.RSAG_01059	5.81e-219	603.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia,3WJ83@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_03113	457412.RSAG_01060	3.8e-179	499.0	COG0703@1|root,COG1605@1|root,COG0703@2|Bacteria,COG1605@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,3WJBW@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
NHEHCBFB_03114	457412.RSAG_01061	3.3e-301	821.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WGET@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NHEHCBFB_03115	1121115.AXVN01000001_gene1043	9.84e-192	531.0	COG0770@1|root,COG0770@2|Bacteria,1V1NG@1239|Firmicutes,24GE1@186801|Clostridia,3Y02I@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
NHEHCBFB_03116	457412.RSAG_01064	1.94e-129	368.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,3WJD2@541000|Ruminococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
NHEHCBFB_03117	1121115.AXVN01000001_gene1045	2.91e-187	521.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,3XYTH@572511|Blautia	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
NHEHCBFB_03118	457412.RSAG_01066	4.47e-199	551.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,3WJK2@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NHEHCBFB_03119	457412.RSAG_01067	1.55e-251	689.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,3WI4Q@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
NHEHCBFB_03120	457412.RSAG_01068	7.81e-282	771.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,3WHE1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NHEHCBFB_03121	1121115.AXVN01000001_gene1049	0.0	1050.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3XZ8D@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
NHEHCBFB_03122	1121115.AXVN01000001_gene1050	3.98e-29	104.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,3Y0K6@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
NHEHCBFB_03123	1121115.AXVN01000001_gene1051	0.0	1625.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3XYZ6@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NHEHCBFB_03124	1121115.AXVN01000001_gene1052	7.49e-301	820.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3XYHR@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
NHEHCBFB_03125	457412.RSAG_01073	9.58e-203	575.0	COG5263@1|root,COG5263@2|Bacteria,1TPVT@1239|Firmicutes,24DEH@186801|Clostridia,3WQ86@541000|Ruminococcaceae	186801|Clostridia	M	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,LRR_5,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N
NHEHCBFB_03126	1121115.AXVN01000001_gene1054	1.1e-29	109.0	2F3CT@1|root,33W6S@2|Bacteria,1VVCN@1239|Firmicutes,250TA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03127	457412.RSAG_01076	3.69e-33	114.0	2FGS5@1|root,348MK@2|Bacteria,1W0U5@1239|Firmicutes,2540A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03128	457412.RSAG_01077	4.78e-79	235.0	2BB22@1|root,325BH@2|Bacteria,1URE9@1239|Firmicutes,259TU@186801|Clostridia,3WQP9@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03129	1121115.AXVN01000001_gene1057	1.49e-54	171.0	2EMJQ@1|root,32KAG@2|Bacteria,1URUU@1239|Firmicutes,259SC@186801|Clostridia,3Y0NU@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03130	1121115.AXVN01000001_gene1058	6.97e-99	289.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3Y099@572511|Blautia	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
NHEHCBFB_03131	1121115.AXVN01000001_gene1059	5.22e-120	343.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,3XZV4@572511|Blautia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
NHEHCBFB_03132	1121115.AXVN01000001_gene1060	0.0	878.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,3XYI9@572511|Blautia	186801|Clostridia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
NHEHCBFB_03133	457412.RSAG_01082	1.56e-49	160.0	COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes,2580C@186801|Clostridia,3WKG8@541000|Ruminococcaceae	186801|Clostridia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
NHEHCBFB_03134	457412.RSAG_01083	2.41e-141	399.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,3WIUW@541000|Ruminococcaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
NHEHCBFB_03135	457412.RSAG_01084	7.36e-55	171.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,3WJWB@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
NHEHCBFB_03136	457412.RSAG_01085	4.47e-198	550.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3WGMS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
NHEHCBFB_03137	1121115.AXVN01000001_gene1065	0.0	1146.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,3XZD2@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
NHEHCBFB_03138	1121115.AXVN01000001_gene1066	0.0	1023.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3XYSE@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
NHEHCBFB_03139	1121115.AXVN01000001_gene1067	1.98e-312	853.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZAY@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	mepA_10	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_03140	457412.RSAG_01089	0.0	1651.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,3WH0P@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
NHEHCBFB_03141	457412.RSAG_01090	0.0	1377.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae	186801|Clostridia	J	translation elongation	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
NHEHCBFB_03142	1121115.AXVN01000001_gene1070	5.93e-261	715.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,3XZI7@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
NHEHCBFB_03143	457412.RSAG_01092	8.46e-301	821.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,3WG99@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
NHEHCBFB_03144	1121115.AXVN01000001_gene1072	8.09e-235	646.0	COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,249PP@186801|Clostridia,3XZ54@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	ldhA	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,PTS-HPr
NHEHCBFB_03145	457412.RSAG_01094	3.92e-41	139.0	2F54G@1|root,33XRK@2|Bacteria,1VVDU@1239|Firmicutes,250QM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03146	1121115.AXVN01000001_gene1074	2.58e-131	372.0	COG0655@1|root,COG0655@2|Bacteria,1TQKC@1239|Firmicutes,24H9P@186801|Clostridia,3Y053@572511|Blautia	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NHEHCBFB_03147	1121115.AXVN01000001_gene1075	1.01e-281	775.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia,3XZ2C@572511|Blautia	186801|Clostridia	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
NHEHCBFB_03148	1121115.AXVN01000001_gene1076	1.72e-251	689.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3XZ7B@572511|Blautia	186801|Clostridia	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
NHEHCBFB_03149	1121115.AXVN01000001_gene1077	9.06e-182	505.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,3XYT2@572511|Blautia	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
NHEHCBFB_03150	457412.RSAG_01192	1.08e-113	326.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,3WIMH@541000|Ruminococcaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
NHEHCBFB_03151	1121115.AXVN01000001_gene1079	3.47e-40	133.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,3Y0D4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
NHEHCBFB_03152	1121115.AXVN01000001_gene1080	1.77e-51	162.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,3Y0EA@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
NHEHCBFB_03153	1121115.AXVN01000001_gene1081	4.29e-310	847.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3XZA0@572511|Blautia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
NHEHCBFB_03154	1121115.AXVN01000001_gene1082	1.92e-67	204.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,3Y0C3@572511|Blautia	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
NHEHCBFB_03155	891391.LAC30SC_01360	1.23e-49	180.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae	91061|Bacilli	L	Belongs to the 'phage' integrase family	int7	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NHEHCBFB_03162	411459.RUMOBE_01397	4.89e-70	211.0	2DWWM@1|root,34290@2|Bacteria,1VWVN@1239|Firmicutes,251UC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03163	397290.C810_01426	1.56e-39	148.0	COG1674@1|root,COG1787@1|root,COG1674@2|Bacteria,COG1787@2|Bacteria,1VBYF@1239|Firmicutes,24R49@186801|Clostridia,27MRP@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Ftsk_gamma,Mrr_cat,zf-C4_Topoisom
NHEHCBFB_03164	411459.RUMOBE_01396	6.65e-23	89.0	2ESED@1|root,30GTB@2|Bacteria,1UGKB@1239|Firmicutes,25P2V@186801|Clostridia,3Y23S@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03165	411459.RUMOBE_01395	6.14e-32	111.0	29UVC@1|root,30G7T@2|Bacteria,1UFE0@1239|Firmicutes,25PDS@186801|Clostridia,3Y25R@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03166	411902.CLOBOL_02557	1.19e-17	87.8	2C3RZ@1|root,33PBS@2|Bacteria,1VSX3@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03167	411460.RUMTOR_02008	7.42e-09	56.2	2DRI9@1|root,33BWS@2|Bacteria,1VKIC@1239|Firmicutes,24V1I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03168	411459.RUMOBE_01391	6.14e-92	275.0	COG3646@1|root,COG3646@2|Bacteria,1VFZC@1239|Firmicutes,24AEZ@186801|Clostridia,3Y0MR@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	rha	-	-	-	-	-	-	-	-	-	-	-	ANT,ORF6C,Phage_pRha
NHEHCBFB_03170	411459.RUMOBE_01384	0.0	1002.0	COG5412@1|root,COG5412@2|Bacteria,1TRXJ@1239|Firmicutes,25MTF@186801|Clostridia,3Y04H@572511|Blautia	186801|Clostridia	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03171	411459.RUMOBE_01382	1.71e-63	197.0	2BXDI@1|root,2ZGQ2@2|Bacteria,1UGM8@1239|Firmicutes,25A8V@186801|Clostridia,3Y0U8@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03174	411459.RUMOBE_01390	1.29e-50	161.0	2FKR9@1|root,2ZUC3@2|Bacteria,1W69M@1239|Firmicutes,255P4@186801|Clostridia,3Y25W@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03175	1226322.HMPREF1545_02575	3.23e-43	150.0	COG3617@1|root,COG3645@1|root,COG3617@2|Bacteria,COG3645@2|Bacteria,1TPKA@1239|Firmicutes,24BSZ@186801|Clostridia,2N892@216572|Oscillospiraceae	186801|Clostridia	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ANT,Bro-N
NHEHCBFB_03180	397290.C810_05176	2.84e-204	593.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia	186801|Clostridia	L	Virulence-associated protein E	-	-	-	-	-	-	-	-	-	-	-	-	VirE
NHEHCBFB_03182	411459.RUMOBE_01375	5.04e-39	129.0	28WDQ@1|root,2ZIE0@2|Bacteria,1W2F2@1239|Firmicutes,24VFI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03184	411459.RUMOBE_01373	3.57e-81	241.0	COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes	1239|Firmicutes	K	Transcriptional	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NHEHCBFB_03185	411459.RUMOBE_01372	5.3e-157	439.0	296AR@1|root,2ZTKM@2|Bacteria,1W43N@1239|Firmicutes,256YA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03187	1122172.KB890259_gene1149	8.37e-43	140.0	COG4115@1|root,COG4115@2|Bacteria,37CEK@32066|Fusobacteria	32066|Fusobacteria	S	YoeB-like toxin of bacterial type II toxin-antitoxin system	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
NHEHCBFB_03188	877411.JMMA01000002_gene2995	5.2e-37	126.0	COG2161@1|root,COG2161@2|Bacteria,1U5W5@1239|Firmicutes,25N6V@186801|Clostridia,3WQY3@541000|Ruminococcaceae	186801|Clostridia	D	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03189	1121115.AXVN01000001_gene1093	1.99e-285	780.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3XYJM@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
NHEHCBFB_03190	1121115.AXVN01000001_gene1094	3.89e-216	598.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3XZT9@572511|Blautia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
NHEHCBFB_03191	457412.RSAG_04662	0.0	1855.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,3WH4V@541000|Ruminococcaceae	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
NHEHCBFB_03192	1121115.AXVN01000001_gene1096	8.03e-159	445.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3XZ9W@572511|Blautia	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
NHEHCBFB_03193	1121115.AXVN01000001_gene1097	6.78e-42	137.0	COG0236@1|root,COG0236@2|Bacteria,1UGNP@1239|Firmicutes,25P5Y@186801|Clostridia,3Y0KT@572511|Blautia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NHEHCBFB_03194	1121115.AXVN01000001_gene1098	6.17e-238	655.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,3XYGR@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
NHEHCBFB_03195	457412.RSAG_01204	0.0	1159.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,3WGT9@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
NHEHCBFB_03196	457412.RSAG_01205	8.57e-164	461.0	2ESCZ@1|root,33JXR@2|Bacteria,1VRFX@1239|Firmicutes,24YXB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03197	1256908.HMPREF0373_01464	2.78e-37	125.0	2CDFN@1|root,32SPI@2|Bacteria,1VE6M@1239|Firmicutes,24MYF@186801|Clostridia,25XP3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03198	500632.CLONEX_01481	3.81e-170	475.0	COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,24AD8@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	mta	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
NHEHCBFB_03199	665950.HMPREF1025_00892	4.99e-228	629.0	COG1396@1|root,COG1396@2|Bacteria,1TQZJ@1239|Firmicutes,25E5Y@186801|Clostridia,27IYF@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_03200	1121115.AXVN01000100_gene825	3.76e-300	827.0	COG4467@1|root,COG4467@2|Bacteria,1UYI4@1239|Firmicutes,2497B@186801|Clostridia	186801|Clostridia	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
NHEHCBFB_03201	1121115.AXVN01000100_gene827	1.16e-24	92.8	2FJB1@1|root,34B0Y@2|Bacteria,1VZVR@1239|Firmicutes,253R9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03202	1121115.AXVN01000113_gene2373	2.48e-129	374.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia,3XZD0@572511|Blautia	186801|Clostridia	S	Replication initiator protein A (RepA) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
NHEHCBFB_03203	1121115.AXVN01000113_gene2374	8.85e-135	390.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,3XYKZ@572511|Blautia	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
NHEHCBFB_03204	457412.RSAG_01608	2.88e-86	258.0	COG4200@1|root,COG4200@2|Bacteria,1V78D@1239|Firmicutes,25D9T@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	mutE	-	-	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
NHEHCBFB_03205	457412.RSAG_01607	1.1e-164	461.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,3WHM4@541000|Ruminococcaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
NHEHCBFB_03206	698769.JFBD01000024_gene1884	2.65e-84	253.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli,4C6TS@84406|Virgibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03207	742765.HMPREF9457_01594	9.86e-69	209.0	2D04F@1|root,32T7R@2|Bacteria,1VBXI@1239|Firmicutes,24N5C@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2500
NHEHCBFB_03208	742765.HMPREF9457_01593	2.36e-120	347.0	28JM5@1|root,2Z9DQ@2|Bacteria,1TS2D@1239|Firmicutes,24D3M@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03209	1121115.AXVN01000049_gene1321	0.0	894.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3XYP4@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pbuX	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
NHEHCBFB_03211	1256908.HMPREF0373_00822	0.0	870.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,25WG7@186806|Eubacteriaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
NHEHCBFB_03212	1121115.AXVN01000001_gene1091	8.52e-26	102.0	COG1895@1|root,COG1895@2|Bacteria,1VG5F@1239|Firmicutes,24H0D@186801|Clostridia,3Y03W@572511|Blautia	186801|Clostridia	S	conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
NHEHCBFB_03213	1121115.AXVN01000001_gene1092	7.29e-77	229.0	COG1669@1|root,COG1669@2|Bacteria,1VFCZ@1239|Firmicutes,24N6Y@186801|Clostridia,3Y07H@572511|Blautia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
NHEHCBFB_03214	1280698.AUJS01000036_gene57	1.12e-129	371.0	COG1476@1|root,COG1476@2|Bacteria,1UUSK@1239|Firmicutes,247YW@186801|Clostridia,27VTS@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Zn_ribbon_2
NHEHCBFB_03215	742735.HMPREF9467_05210	8.08e-195	554.0	COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,24CFF@186801|Clostridia,221YR@1506553|Lachnoclostridium	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NHEHCBFB_03223	411460.RUMTOR_01995	9.18e-270	742.0	COG0582@1|root,COG0582@2|Bacteria,1V1W1@1239|Firmicutes,24G5V@186801|Clostridia,3XZQN@572511|Blautia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NHEHCBFB_03224	411461.DORFOR_00514	5.5e-200	553.0	28KEB@1|root,2ZA0K@2|Bacteria,1V14E@1239|Firmicutes,24UU8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03225	1232453.BAIF02000067_gene2006	3.74e-69	209.0	2DKVE@1|root,30GA7@2|Bacteria,1V61Z@1239|Firmicutes,24HJK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03226	1232453.BAIF02000067_gene2007	2.93e-88	259.0	COG1396@1|root,COG1396@2|Bacteria,1VHJY@1239|Firmicutes,24S29@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_03227	411461.DORFOR_00517	5.46e-71	213.0	2CPFJ@1|root,32SIZ@2|Bacteria,1VDQ2@1239|Firmicutes,24NGA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03228	411459.RUMOBE_03566	8.09e-48	152.0	29XB6@1|root,30J0U@2|Bacteria,1VX6B@1239|Firmicutes,2524W@186801|Clostridia,3Y0GW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
NHEHCBFB_03229	471875.RUMLAC_01420	3.97e-72	217.0	2C9NK@1|root,32RPI@2|Bacteria,1V7S6@1239|Firmicutes,25CVV@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
NHEHCBFB_03230	742765.HMPREF9457_03296	3.54e-177	493.0	COG2267@1|root,COG2267@2|Bacteria,1UIFD@1239|Firmicutes,25EKS@186801|Clostridia	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
NHEHCBFB_03231	471875.RUMLAC_01421	3.76e-64	196.0	2BBQM@1|root,3258R@2|Bacteria,1URCD@1239|Firmicutes,2597J@186801|Clostridia,3WPMG@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03232	411461.DORFOR_00520	6.82e-58	181.0	2DVAH@1|root,32UZ0@2|Bacteria,1VPPD@1239|Firmicutes,24VP7@186801|Clostridia,27WU9@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
NHEHCBFB_03233	1121115.AXVN01000205_gene3699	3.48e-44	143.0	2CCVX@1|root,33G73@2|Bacteria,1VN7A@1239|Firmicutes,24W0K@186801|Clostridia,3Y25Z@572511|Blautia	186801|Clostridia	S	FeoA domain	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
NHEHCBFB_03234	1121115.AXVN01000205_gene3700	1.45e-38	128.0	2EMF6@1|root,33F40@2|Bacteria,1VPJF@1239|Firmicutes,24VFH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03235	457412.RSAG_04607	5.12e-38	127.0	298ED@1|root,2ZVJK@2|Bacteria,1W2SQ@1239|Firmicutes,2571M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03236	1121115.AXVN01000030_gene3643	4.81e-56	175.0	2CA4P@1|root,33W70@2|Bacteria,1VVK6@1239|Firmicutes,251F5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03237	1121115.AXVN01000030_gene3642	4.61e-167	468.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,3XZX5@572511|Blautia	186801|Clostridia	K	FCD domain	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
NHEHCBFB_03238	552396.HMPREF0863_00167	5e-11	65.9	COG1396@1|root,COG1396@2|Bacteria,1VA98@1239|Firmicutes,3VRXG@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_03239	1235798.C817_05064	1.02e-09	55.8	2EQGP@1|root,33I2P@2|Bacteria,1VKY1@1239|Firmicutes,24US2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03240	642492.Clole_1479	2.35e-22	98.6	COG3935@1|root,COG3935@2|Bacteria,1W6YJ@1239|Firmicutes,24P7D@186801|Clostridia	186801|Clostridia	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03241	397291.C804_01604	2.56e-83	256.0	COG1484@1|root,COG1484@2|Bacteria,1V8DQ@1239|Firmicutes,24M56@186801|Clostridia,27NQC@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Bacterial dnaA  protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA,IstB_IS21
NHEHCBFB_03244	411459.RUMOBE_01395	9.04e-34	116.0	29UVC@1|root,30G7T@2|Bacteria,1UFE0@1239|Firmicutes,25PDS@186801|Clostridia,3Y25R@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03245	1519439.JPJG01000054_gene2127	7.35e-22	86.7	2BCKR@1|root,3266U@2|Bacteria,1US5H@1239|Firmicutes,25A4B@186801|Clostridia,2N8VG@216572|Oscillospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03246	411459.RUMOBE_01397	3.89e-53	169.0	2DWWM@1|root,34290@2|Bacteria,1VWVN@1239|Firmicutes,251UC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03248	97139.C824_02830	6.44e-118	353.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,36F0S@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
NHEHCBFB_03249	457412.RSAG_03342	0.0	1128.0	COG3044@1|root,COG3044@2|Bacteria,1TPJ9@1239|Firmicutes,248G5@186801|Clostridia,3WHYM@541000|Ruminococcaceae	186801|Clostridia	S	Predicted ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
NHEHCBFB_03250	1121115.AXVN01000030_gene3640	0.0	897.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,3XZF0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
NHEHCBFB_03251	1121115.AXVN01000030_gene3639	4.29e-171	478.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3XYST@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_03252	457412.RSAG_03345	1.09e-288	806.0	COG0845@1|root,COG0845@2|Bacteria,1UZA4@1239|Firmicutes,24BV0@186801|Clostridia,3WJXH@541000|Ruminococcaceae	186801|Clostridia	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NHEHCBFB_03253	1121115.AXVN01000030_gene3637	9.21e-271	744.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3XZ8E@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	macB2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NHEHCBFB_03255	457412.RSAG_03360	1.01e-251	690.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,3WG84@541000|Ruminococcaceae	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
NHEHCBFB_03256	457412.RSAG_03361	1.21e-46	149.0	2E7R6@1|root,3326H@2|Bacteria,1VGKC@1239|Firmicutes,24QSS@186801|Clostridia,3WQM5@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03257	457412.RSAG_03362	3.06e-120	343.0	COG0454@1|root,COG0454@2|Bacteria,1V9X4@1239|Firmicutes,24G56@186801|Clostridia,3WSS2@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NHEHCBFB_03258	457412.RSAG_03363	2.72e-173	482.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,249BN@186801|Clostridia,3WIIA@541000|Ruminococcaceae	186801|Clostridia	S	Ser Thr phosphatase family protein	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
NHEHCBFB_03259	1121115.AXVN01000030_gene3615	3.3e-241	665.0	28KXK@1|root,2ZADH@2|Bacteria,1V79T@1239|Firmicutes,24K1T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
NHEHCBFB_03260	457412.RSAG_03365	0.0	910.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia,3WH2V@541000|Ruminococcaceae	186801|Clostridia	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
NHEHCBFB_03261	1121115.AXVN01000030_gene3613	0.0	1003.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3XZAA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
NHEHCBFB_03262	1121115.AXVN01000030_gene3612	4.81e-90	266.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia,3Y0FJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
NHEHCBFB_03263	457412.RSAG_03384	1.78e-203	563.0	COG2207@1|root,COG2207@2|Bacteria,1V48H@1239|Firmicutes,248BW@186801|Clostridia,3WRJT@541000|Ruminococcaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NHEHCBFB_03264	457412.RSAG_03385	1.65e-147	415.0	28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,247W6@186801|Clostridia,3WIDK@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4867
NHEHCBFB_03265	457412.RSAG_03386	0.0	1018.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3WGMD@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
NHEHCBFB_03266	1121115.AXVN01000030_gene3608	0.0	984.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3XYSC@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
NHEHCBFB_03267	1121115.AXVN01000030_gene3607	3.26e-225	620.0	COG0583@1|root,COG0583@2|Bacteria,1UYAI@1239|Firmicutes,24BA8@186801|Clostridia,3XZQR@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NHEHCBFB_03268	1121115.AXVN01000030_gene3606	0.0	930.0	COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,2483Z@186801|Clostridia,3Y0Z4@572511|Blautia	186801|Clostridia	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
NHEHCBFB_03269	457412.RSAG_03390	0.0	1102.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
NHEHCBFB_03270	457412.RSAG_03391	0.0	946.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3WGP2@541000|Ruminococcaceae	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
NHEHCBFB_03271	1121115.AXVN01000128_gene276	9.27e-217	597.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,3XZ5Q@572511|Blautia	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
NHEHCBFB_03272	1121115.AXVN01000128_gene275	1.17e-308	841.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,3XYN8@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
NHEHCBFB_03273	1121115.AXVN01000128_gene274	9.78e-281	766.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia,3XYIP@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
NHEHCBFB_03274	1121115.AXVN01000128_gene273	6.36e-283	771.0	COG2957@1|root,COG2957@2|Bacteria,1TQS5@1239|Firmicutes,248CP@186801|Clostridia	186801|Clostridia	E	agmatine deiminase	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
NHEHCBFB_03275	1121115.AXVN01000128_gene272	7.64e-219	602.0	COG0388@1|root,COG0388@2|Bacteria,1TRMU@1239|Firmicutes,25B19@186801|Clostridia	186801|Clostridia	S	N-carbamoylputrescine amidase	aguB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
NHEHCBFB_03276	457412.RSAG_03397	1.38e-91	269.0	2E4RH@1|root,32ZK1@2|Bacteria,1VEUS@1239|Firmicutes,24QIW@186801|Clostridia,3WMFG@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NHEHCBFB_03277	1121115.AXVN01000106_gene668	0.0	2940.0	COG3468@1|root,COG4932@1|root,COG3468@2|Bacteria,COG4932@2|Bacteria,1UVFP@1239|Firmicutes,25MSF@186801|Clostridia,3Y1Y1@572511|Blautia	186801|Clostridia	M	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03278	457412.RSAG_03399	2.12e-197	548.0	COG4509@1|root,COG4509@2|Bacteria,1V2FT@1239|Firmicutes,24GN2@186801|Clostridia,3WK8B@541000|Ruminococcaceae	186801|Clostridia	S	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
NHEHCBFB_03279	1121115.AXVN01000106_gene670	9.56e-267	729.0	COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,24ARJ@186801|Clostridia,3Y051@572511|Blautia	186801|Clostridia	K	Periplasmic binding protein-like domain	araR	-	-	ko:K02103	-	-	-	-	ko00000,ko03000	-	-	-	GntR,Peripla_BP_3
NHEHCBFB_03280	1121115.AXVN01000106_gene671	0.0	1024.0	COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,24A08@186801|Clostridia,3XYUS@572511|Blautia	186801|Clostridia	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
NHEHCBFB_03281	457412.RSAG_03402	0.0	1074.0	COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia,3WH01@541000|Ruminococcaceae	186801|Clostridia	G	Carbohydrate kinase, FGGY family protein	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NHEHCBFB_03282	1121115.AXVN01000198_gene2446	1.69e-33	115.0	2FGU2@1|root,348PD@2|Bacteria,1VZBU@1239|Firmicutes,252UE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03283	1121115.AXVN01000198_gene2447	6.29e-71	213.0	COG0607@1|root,COG0607@2|Bacteria,1VGXK@1239|Firmicutes,24R46@186801|Clostridia,3Y0GN@572511|Blautia	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
NHEHCBFB_03284	1121115.AXVN01000146_gene770	7.16e-132	373.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,3XZ4B@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NHEHCBFB_03285	1121115.AXVN01000146_gene771	2.72e-283	773.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,3XYQ3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
NHEHCBFB_03286	457412.RSAG_02198	2.64e-134	380.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,3WIUM@541000|Ruminococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
NHEHCBFB_03287	1121115.AXVN01000146_gene773	2.48e-115	330.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,3Y05G@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NHEHCBFB_03295	457412.RSAG_02196	8.44e-163	457.0	COG0568@1|root,COG0568@2|Bacteria,1W6ZB@1239|Firmicutes,25MJD@186801|Clostridia,3WQKW@541000|Ruminococcaceae	186801|Clostridia	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03296	1121115.AXVN01000146_gene775	7.72e-165	461.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,3Y00D@572511|Blautia	186801|Clostridia	F	Phosphorylase superfamily	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
NHEHCBFB_03297	457412.RSAG_02194	7.21e-81	240.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,3WKJ7@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
NHEHCBFB_03298	457412.RSAG_02193	3.6e-214	592.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,3WGBT@541000|Ruminococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NHEHCBFB_03299	457412.RSAG_02192	9.63e-306	836.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,3WGX2@541000|Ruminococcaceae	186801|Clostridia	S	xanthine uracil permease family protein K06901	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
NHEHCBFB_03300	1121115.AXVN01000024_gene284	3.13e-313	852.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3XZ7R@572511|Blautia	186801|Clostridia	F	COG COG0402 Cytosine deaminase and related metal-dependent hydrolases	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NHEHCBFB_03301	457412.RSAG_02190	3.93e-239	661.0	COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,25CCK@186801|Clostridia,3WH44@541000|Ruminococcaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NHEHCBFB_03302	1121115.AXVN01000024_gene287	5.34e-81	240.0	2EC8D@1|root,3366W@2|Bacteria,1VEI1@1239|Firmicutes,24WC7@186801|Clostridia	186801|Clostridia	S	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NHEHCBFB_03303	1121115.AXVN01000024_gene288	2.07e-302	823.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3XYUF@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
NHEHCBFB_03304	457412.RSAG_02187	1.39e-255	700.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,3WGZJ@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
NHEHCBFB_03305	457412.RSAG_02186	5.54e-286	782.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,3WGSI@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
NHEHCBFB_03306	1121115.AXVN01000024_gene291	1.86e-213	589.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,3XZI8@572511|Blautia	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
NHEHCBFB_03307	1121115.AXVN01000024_gene292	6.01e-289	788.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3XYZW@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NHEHCBFB_03308	1121115.AXVN01000024_gene293	8.17e-302	825.0	COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia,3Y0QZ@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NHEHCBFB_03309	457412.RSAG_02182	1.14e-168	471.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24DB9@186801|Clostridia,3WHMG@541000|Ruminococcaceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NHEHCBFB_03310	1121115.AXVN01000024_gene295	2.23e-65	201.0	COG3279@1|root,COG3279@2|Bacteria,1VAGQ@1239|Firmicutes,24Q19@186801|Clostridia,3Y1RE@572511|Blautia	186801|Clostridia	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
NHEHCBFB_03311	457412.RSAG_02180	0.0	1286.0	COG1520@1|root,COG1520@2|Bacteria,1UKI6@1239|Firmicutes,25FXQ@186801|Clostridia	186801|Clostridia	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03312	1121115.AXVN01000032_gene408	2.36e-65	199.0	2E82Y@1|root,332GY@2|Bacteria,1VEU7@1239|Firmicutes,24P37@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03313	457412.RSAG_02179	0.0	1353.0	COG5263@1|root,COG5263@2|Bacteria,1VIRC@1239|Firmicutes	1239|Firmicutes	N	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03314	1121115.AXVN01000024_gene312	3.12e-95	278.0	COG3238@1|root,COG3238@2|Bacteria,1V6J0@1239|Firmicutes,24JM9@186801|Clostridia,3Y03G@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
NHEHCBFB_03315	457412.RSAG_02177	3.68e-181	507.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,3WM12@541000|Ruminococcaceae	186801|Clostridia	L	TIGRFAM competence protein ComEA helix-hairpin-helix repeat	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
NHEHCBFB_03316	1121115.AXVN01000024_gene314	9.41e-164	458.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,3XYMR@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NHEHCBFB_03317	1121115.AXVN01000024_gene315	3.66e-113	324.0	COG1905@1|root,COG1905@2|Bacteria,1V4IR@1239|Firmicutes,25CD0@186801|Clostridia,3XZET@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
NHEHCBFB_03318	1121115.AXVN01000024_gene316	0.0	1213.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3XZ6P@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
NHEHCBFB_03319	1121115.AXVN01000024_gene317	0.0	1857.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,3XYRD@572511|Blautia	186801|Clostridia	C	Molydopterin dinucleotide binding domain	fdhA2	-	1.17.1.11,1.17.1.9	ko:K00123,ko:K22341	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
NHEHCBFB_03320	457412.RSAG_02171	0.0	1121.0	COG2221@1|root,COG4624@1|root,COG2221@2|Bacteria,COG4624@2|Bacteria,1TRB4@1239|Firmicutes,24YQ5@186801|Clostridia,3WGXS@541000|Ruminococcaceae	186801|Clostridia	C	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,PAS
NHEHCBFB_03321	457412.RSAG_02170	4.44e-293	799.0	COG2208@1|root,COG2208@2|Bacteria,1TQUC@1239|Firmicutes,248FZ@186801|Clostridia,3WGNY@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
NHEHCBFB_03322	457412.RSAG_02169	1.27e-103	299.0	COG2258@1|root,COG2258@2|Bacteria,1W5YX@1239|Firmicutes,255UB@186801|Clostridia	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03323	1121115.AXVN01000022_gene1765	6.18e-301	821.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,248WP@186801|Clostridia,3Y0HF@572511|Blautia	186801|Clostridia	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
NHEHCBFB_03324	1121115.AXVN01000022_gene1764	1.46e-117	336.0	COG1763@1|root,COG1763@2|Bacteria,1VFA0@1239|Firmicutes,24IYN@186801|Clostridia	186801|Clostridia	H	molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
NHEHCBFB_03325	1121115.AXVN01000022_gene1763	4.35e-199	551.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia	186801|Clostridia	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
NHEHCBFB_03326	457412.RSAG_02165	9.87e-238	653.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,3WHWT@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
NHEHCBFB_03327	457412.RSAG_02164	4.16e-130	369.0	2A753@1|root,30W0Z@2|Bacteria,1TU7M@1239|Firmicutes,25N2S@186801|Clostridia,3WMN0@541000|Ruminococcaceae	186801|Clostridia	S	Toxin ToxN, type III toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	ToxN_toxin
NHEHCBFB_03328	1121115.AXVN01000022_gene1761	6.24e-135	383.0	COG0746@1|root,COG0746@2|Bacteria,1UQ1Y@1239|Firmicutes,257PR@186801|Clostridia,3Y0VI@572511|Blautia	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
NHEHCBFB_03329	411461.DORFOR_03332	1.47e-285	780.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,27W6F@189330|Dorea	186801|Clostridia	L	DNA binding domain of tn916 integrase	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_5,Phage_integrase
NHEHCBFB_03330	1232447.BAHW02000034_gene2488	7.18e-42	137.0	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24PBS@186801|Clostridia,26CGR@186813|unclassified Clostridiales	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NHEHCBFB_03331	500632.CLONEX_00007	5.66e-279	762.0	COG2946@1|root,COG2946@2|Bacteria,1UE6H@1239|Firmicutes,24AH3@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Rep_trans
NHEHCBFB_03332	411461.DORFOR_03336	7.42e-148	416.0	COG1476@1|root,COG1476@2|Bacteria,1TRBW@1239|Firmicutes,24CX9@186801|Clostridia,27WMT@189330|Dorea	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_03333	500632.CLONEX_00002	0.0	915.0	COG4886@1|root,COG4932@1|root,COG4886@2|Bacteria,COG4932@2|Bacteria,1V3DU@1239|Firmicutes,24GSD@186801|Clostridia	186801|Clostridia	U	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CW_binding_2,DUF5011
NHEHCBFB_03334	1234679.BN424_1079	2.14e-279	764.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,27FPR@186828|Carnobacteriaceae	91061|Bacilli	L	L COG3328 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
NHEHCBFB_03335	176279.SERP1585	0.0	975.0	COG1670@1|root,COG3173@1|root,COG1670@2|Bacteria,COG3173@2|Bacteria,1V1G0@1239|Firmicutes,4I3EZ@91061|Bacilli,4GYHN@90964|Staphylococcaceae	91061|Bacilli	F	Involved in resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region. The C-terminal region is a kinase that phosphorylates several 4,6-disubstituted aminoglycosides	-	-	2.3.1.82,2.7.1.190	ko:K19883	-	-	R11229	RC00002,RC00078	ko00000,ko01000,ko01504	-	-	-	APH,Acetyltransf_8
NHEHCBFB_03336	1280.SAXN108_2178	2.83e-92	269.0	COG0454@1|root,COG0456@2|Bacteria,1TXSN@1239|Firmicutes,4I6UP@91061|Bacilli,4GZ1F@90964|Staphylococcaceae	91061|Bacilli	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NHEHCBFB_03337	1449338.JQLU01000001_gene928	0.0	974.0	COG1959@1|root,COG1959@2|Bacteria,1UBUD@1239|Firmicutes,4HB0A@91061|Bacilli,27H8Y@186828|Carnobacteriaceae	91061|Bacilli	K	Primase C terminal 1 (PriCT-1)	repE	-	-	-	-	-	-	-	-	-	-	-	PriCT_1
NHEHCBFB_03338	565653.EGBG_00002	4.1e-25	96.7	29K9A@1|root,3076M@2|Bacteria,1U14H@1239|Firmicutes,4IAKD@91061|Bacilli,4B5N1@81852|Enterococcaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_03339	1158604.I591_02847	2.19e-16	70.9	2A8RU@1|root,30XUI@2|Bacteria,1VHZC@1239|Firmicutes,4IBX8@91061|Bacilli,4B49K@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03340	562982.HMPREF0432_00430	1.28e-173	484.0	COG0030@1|root,COG0030@2|Bacteria,1UY9S@1239|Firmicutes,4HC16@91061|Bacilli	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	ermA	-	2.1.1.184	ko:K00561	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
NHEHCBFB_03341	457412.RSAG_00902	2.74e-195	546.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
NHEHCBFB_03342	457412.RSAG_03502	0.0	902.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,3WIJ3@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
NHEHCBFB_03343	457412.RSAG_04690	2.65e-305	832.0	COG3385@1|root,COG3385@2|Bacteria,1UHBB@1239|Firmicutes,24ETX@186801|Clostridia	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NHEHCBFB_03344	632335.Calkr_2394	3.68e-152	443.0	COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,248VD@186801|Clostridia,42FT8@68295|Thermoanaerobacterales	186801|Clostridia	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
NHEHCBFB_03345	910313.HMPREF9320_2057	8.01e-05	46.6	COG1476@1|root,COG1476@2|Bacteria,1TNYC@1239|Firmicutes,4HPZC@91061|Bacilli	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NHEHCBFB_03347	411470.RUMGNA_01135	1.05e-203	563.0	COG2801@1|root,COG2801@2|Bacteria,1TRNK@1239|Firmicutes,24B7I@186801|Clostridia,3Y0HR@572511|Blautia	186801|Clostridia	L	COG COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
NHEHCBFB_03348	411470.RUMGNA_01134	9.52e-74	221.0	COG2963@1|root,COG2963@2|Bacteria,1VE6Y@1239|Firmicutes,25BJ2@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
NHEHCBFB_03349	457412.RSAG_00891	5.43e-179	498.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia,3WHH1@541000|Ruminococcaceae	186801|Clostridia	S	Peroxide stress protein YaaA	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
NHEHCBFB_03350	457412.RSAG_03500	3.86e-108	320.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
NHEHCBFB_03351	411461.DORFOR_02397	3.47e-32	113.0	COG2452@1|root,COG2452@2|Bacteria,1TQNJ@1239|Firmicutes,24B79@186801|Clostridia	186801|Clostridia	L	protein MJ0014 - Methanococcus jannaschii gi 1590824 gb AAB97992.1 (U67460) conserved	-	-	-	ko:K07450	-	-	-	-	ko00000	-	-	-	MerR,MerR_1,Resolvase
NHEHCBFB_03352	1121115.AXVN01000017_gene271	1.61e-160	449.0	28HI8@1|root,2Z9QV@2|Bacteria,1UZZ2@1239|Firmicutes,24IH2@186801|Clostridia,3XZY4@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
NHEHCBFB_03353	457412.RSAG_00255	1.27e-141	399.0	COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,249EP@186801|Clostridia,3WI1J@541000|Ruminococcaceae	186801|Clostridia	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
NHEHCBFB_03354	1121115.AXVN01000017_gene270	4.49e-158	443.0	COG1787@1|root,COG1787@2|Bacteria,1TTX3@1239|Firmicutes,25P6F@186801|Clostridia,3Y1RR@572511|Blautia	186801|Clostridia	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
NHEHCBFB_03355	457412.RSAG_00253	1e-166	467.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,3WIP0@541000|Ruminococcaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NHEHCBFB_03356	1121115.AXVN01000017_gene268	0.0	920.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,3XZHG@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	ywdH	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
NHEHCBFB_03357	457412.RSAG_00251	1.05e-292	799.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,249X1@186801|Clostridia,3WJCU@541000|Ruminococcaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NHEHCBFB_03359	1121115.AXVN01000017_gene266	2.7e-164	459.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3Y11K@572511|Blautia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NHEHCBFB_03360	1121115.AXVN01000017_gene265	0.0	1254.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,247QW@186801|Clostridia,3Y19B@572511|Blautia	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NHEHCBFB_03361	1121115.AXVN01000017_gene264	5.86e-70	214.0	2BBFY@1|root,324Z7@2|Bacteria,1UR44@1239|Firmicutes,258XU@186801|Clostridia,3Y266@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03362	457412.RSAG_00247	4.68e-314	857.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NHEHCBFB_03363	1121115.AXVN01000017_gene262	6.35e-126	358.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,3Y0A5@572511|Blautia	186801|Clostridia	I	COG COG0671 Membrane-associated phospholipid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
NHEHCBFB_03364	1121115.AXVN01000017_gene261	3.66e-277	756.0	COG2006@1|root,COG2006@2|Bacteria,1TRYQ@1239|Firmicutes,24966@186801|Clostridia,3XZNX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
NHEHCBFB_03365	457412.RSAG_00243	4.22e-136	385.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3WJWK@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NHEHCBFB_03366	457412.RSAG_00242	2.71e-193	536.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia,3WIEX@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain in molybdopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
NHEHCBFB_03367	1121115.AXVN01000017_gene258	1.7e-111	320.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia,3XZVY@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
NHEHCBFB_03368	1121115.AXVN01000017_gene257	0.0	1602.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3XYHY@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
NHEHCBFB_03369	1121115.AXVN01000017_gene256	4.79e-251	690.0	2BDSU@1|root,327GK@2|Bacteria,1UTCR@1239|Firmicutes,258AQ@186801|Clostridia,3Y1YM@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03370	1121115.AXVN01000017_gene255	6.94e-201	556.0	2A5RW@1|root,30UGW@2|Bacteria,1US7T@1239|Firmicutes,25A6N@186801|Clostridia,3Y26D@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03371	457412.RSAG_00237	0.0	1004.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,3WGRM@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	mleN_1	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
NHEHCBFB_03373	457412.RSAG_00236	2.63e-210	582.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
NHEHCBFB_03374	457412.RSAG_00235	1.28e-241	670.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,249SN@186801|Clostridia	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,ChW,Polysacc_deac_1
NHEHCBFB_03375	457412.RSAG_04728	0.0	1269.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WGTP@541000|Ruminococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
NHEHCBFB_03376	1121115.AXVN01000017_gene249	2.4e-231	635.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3XZIH@572511|Blautia	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	HTS
NHEHCBFB_03377	1121115.AXVN01000020_gene98	3.31e-89	262.0	2F70J@1|root,33ZG8@2|Bacteria,1VX30@1239|Firmicutes,251WZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03378	457412.RSAG_00127	2.77e-41	135.0	2EPN8@1|root,33H8W@2|Bacteria,1VM4B@1239|Firmicutes,24VJ3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03379	1235800.C819_00973	1.24e-161	468.0	28P13@1|root,2ZBXI@2|Bacteria,1V1IE@1239|Firmicutes,24M46@186801|Clostridia,27TVN@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03380	1121115.AXVN01000001_gene1125	4.79e-24	113.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	FMN_bind,Flg_new,LRR_5
NHEHCBFB_03383	397290.C810_01709	5.7e-117	343.0	COG4227@1|root,COG4227@2|Bacteria,1UY3K@1239|Firmicutes,24HPV@186801|Clostridia,27Q00@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Domain of unknown function (DUF1738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1738
NHEHCBFB_03386	742740.HMPREF9474_04672	4.93e-49	156.0	2E3EN@1|root,32YDN@2|Bacteria,1VDEB@1239|Firmicutes,25FXN@186801|Clostridia,223DI@1506553|Lachnoclostridium	186801|Clostridia	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
NHEHCBFB_03387	1121115.AXVN01000020_gene101	1.14e-62	191.0	2DZYH@1|root,32VN8@2|Bacteria,1VB55@1239|Firmicutes,24P04@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
NHEHCBFB_03388	457412.RSAG_00230	2.99e-49	156.0	2E45D@1|root,32Z1F@2|Bacteria,1VEXR@1239|Firmicutes,24R89@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03389	457412.RSAG_00229	7.31e-142	400.0	2ESIJ@1|root,33K39@2|Bacteria,1VP26@1239|Firmicutes,25HRK@186801|Clostridia,3WMIB@541000|Ruminococcaceae	186801|Clostridia	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
NHEHCBFB_03390	457412.RSAG_00228	0.0	1063.0	COG0791@1|root,COG0791@2|Bacteria,1UVPP@1239|Firmicutes,25KKC@186801|Clostridia,3WQIY@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
NHEHCBFB_03391	457412.RSAG_00227	0.0	1274.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3WHN6@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HATPase_c,HD,HD_5,Response_reg
NHEHCBFB_03392	457412.RSAG_00226	0.0	1397.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WGH8@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	ptsG	-	2.7.1.199	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	M00809	R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
NHEHCBFB_03393	457412.RSAG_00225	4.19e-198	549.0	COG3711@1|root,COG3711@2|Bacteria,1TQJJ@1239|Firmicutes,249XA@186801|Clostridia,3WIRH@541000|Ruminococcaceae	186801|Clostridia	K	CAT RNA binding domain	bglG	-	-	ko:K03480	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
NHEHCBFB_03394	457412.RSAG_04727	1.51e-114	329.0	2DXFQ@1|root,344TK@2|Bacteria,1TV4T@1239|Firmicutes,259G5@186801|Clostridia,3WQ46@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03395	457412.RSAG_00222	7e-272	741.0	COG0399@1|root,COG0399@2|Bacteria,1TZB6@1239|Firmicutes,249QE@186801|Clostridia,3WHS1@541000|Ruminococcaceae	186801|Clostridia	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03396	1121115.AXVN01000017_gene232	1.42e-40	151.0	COG5492@1|root,COG5492@2|Bacteria,1TT7E@1239|Firmicutes,24J1K@186801|Clostridia	186801|Clostridia	N	Domain of unknown function (DUF5057)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5057
NHEHCBFB_03397	1121115.AXVN01000064_gene4025	0.000708	42.0	28JN4@1|root,31UVI@2|Bacteria,1V2P0@1239|Firmicutes,25EHE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03398	1121115.AXVN01000064_gene4026	1.35e-154	433.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,3Y0B2@572511|Blautia	186801|Clostridia	Q	Phosphate propanoyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PTAC
NHEHCBFB_03399	457412.RSAG_00217	1.53e-289	790.0	COG5279@1|root,COG5279@2|Bacteria,1TY2Q@1239|Firmicutes,24BDS@186801|Clostridia,3WRJG@541000|Ruminococcaceae	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NHEHCBFB_03400	1121115.AXVN01000025_gene944	8.41e-131	377.0	2E6QY@1|root,331B3@2|Bacteria,1UI1C@1239|Firmicutes,24Z9X@186801|Clostridia,3Y0GV@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
NHEHCBFB_03401	457412.RSAG_00215	8.44e-118	337.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,3WIUH@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
NHEHCBFB_03402	1121115.AXVN01000025_gene946	0.0	1071.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia,3XZ1S@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
NHEHCBFB_03403	1121115.AXVN01000025_gene947	2.17e-93	272.0	COG1959@1|root,COG1959@2|Bacteria,1VA5B@1239|Firmicutes,24JMN@186801|Clostridia,3Y09T@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NHEHCBFB_03404	457412.RSAG_00212	0.0	2330.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
NHEHCBFB_03405	1121115.AXVN01000025_gene949	0.0	1767.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24A98@186801|Clostridia,3Y056@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
NHEHCBFB_03406	1121115.AXVN01000025_gene950	6.98e-219	604.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,3XYSZ@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
NHEHCBFB_03407	1121115.AXVN01000025_gene951	1.24e-89	263.0	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,257NM@186801|Clostridia,3Y0BG@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
NHEHCBFB_03408	1121115.AXVN01000025_gene952	1.47e-243	670.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,3XYHW@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
NHEHCBFB_03409	1121115.AXVN01000025_gene953	3.68e-125	356.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,3Y004@572511|Blautia	186801|Clostridia	H	COG COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
NHEHCBFB_03410	1121115.AXVN01000025_gene954	1.23e-182	508.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,3Y00I@572511|Blautia	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
NHEHCBFB_03411	1121115.AXVN01000025_gene955	4.01e-87	256.0	COG2087@1|root,COG2087@2|Bacteria,1VG8S@1239|Firmicutes,24QSM@186801|Clostridia,3Y0HX@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	CobU
NHEHCBFB_03412	1121115.AXVN01000025_gene956	2.18e-149	419.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3XZUY@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
NHEHCBFB_03413	1121115.AXVN01000025_gene957	0.0	915.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3XZEP@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	ssnA	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NHEHCBFB_03414	457412.RSAG_00202	0.0	1977.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TPR4@1239|Firmicutes,248TM@186801|Clostridia,3WRQE@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain	-	-	1.97.1.9	ko:K12527	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
NHEHCBFB_03415	1121115.AXVN01000025_gene959	0.0	1746.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3XYY3@572511|Blautia	186801|Clostridia	C	COG COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	mop	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
NHEHCBFB_03416	457412.RSAG_00200	3.71e-94	276.0	COG1148@1|root,COG1148@2|Bacteria,1V4P9@1239|Firmicutes,24IV2@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
NHEHCBFB_03417	457412.RSAG_00199	0.0	1518.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WHIV@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhA	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
NHEHCBFB_03418	1121115.AXVN01000025_gene962	5.72e-206	570.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia,3XZ4A@572511|Blautia	186801|Clostridia	C	COG COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs	xdhB	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
NHEHCBFB_03419	1121115.AXVN01000025_gene963	4.4e-117	335.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24FZI@186801|Clostridia,3XZZI@572511|Blautia	186801|Clostridia	C	COG COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	cutS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
NHEHCBFB_03420	457412.RSAG_00196	2.83e-205	568.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,3WI66@541000|Ruminococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
NHEHCBFB_03421	457412.RSAG_00195	1.05e-164	461.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,3WKRV@541000|Ruminococcaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03422	457412.RSAG_04726	2.49e-158	444.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24KIZ@186801|Clostridia,3WKNV@541000|Ruminococcaceae	186801|Clostridia	S	MobA-like NTP transferase domain	ygfJ	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
NHEHCBFB_03423	1121115.AXVN01000134_gene411	4.8e-224	617.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,3XZFB@572511|Blautia	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NHEHCBFB_03424	1121115.AXVN01000134_gene412	7.38e-295	803.0	COG0078@1|root,COG0078@2|Bacteria,1TNY4@1239|Firmicutes,249P4@186801|Clostridia,3XYQV@572511|Blautia	186801|Clostridia	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	ygeW	-	-	-	-	-	-	-	-	-	-	-	OTCace,OTCace_N
NHEHCBFB_03425	1121115.AXVN01000134_gene413	0.0	898.0	COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,3XYM0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
NHEHCBFB_03426	1121115.AXVN01000134_gene414	1.92e-303	826.0	COG1171@1|root,COG1171@2|Bacteria,1TR70@1239|Firmicutes,2485T@186801|Clostridia,3XZ80@572511|Blautia	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	dpaL	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
NHEHCBFB_03427	1121115.AXVN01000134_gene415	1.8e-310	844.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,3XZ64@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
NHEHCBFB_03428	1121115.AXVN01000032_gene374	3.18e-41	139.0	28SNZ@1|root,2ZEZ7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03430	1304866.K413DRAFT_4589	2.66e-108	332.0	COG0582@1|root,COG0582@2|Bacteria,1UXH5@1239|Firmicutes,25ME5@186801|Clostridia,36N9U@31979|Clostridiaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NHEHCBFB_03435	556261.HMPREF0240_00403	4.18e-82	256.0	29Z4Y@1|root,30M2N@2|Bacteria,1UUGP@1239|Firmicutes,256QT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NHEHCBFB_03437	1378168.N510_01453	7.91e-67	211.0	COG3091@1|root,COG3091@2|Bacteria,1UHT0@1239|Firmicutes	1239|Firmicutes	S	SprT-like family	-	-	-	-	-	-	-	-	-	-	-	-	SprT-like
NHEHCBFB_03439	411490.ANACAC_00813	1.2e-44	151.0	COG3617@1|root,COG3617@2|Bacteria,1TPKA@1239|Firmicutes,24BSZ@186801|Clostridia	186801|Clostridia	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ANT,Bro-N
NHEHCBFB_03440	1121115.AXVN01000032_gene376	0.0	1110.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,3XYGQ@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
NHEHCBFB_03441	1121115.AXVN01000032_gene377	0.0	1522.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3XZ2A@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NHEHCBFB_03442	1121115.AXVN01000032_gene378	1.01e-183	510.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,3XYYY@572511|Blautia	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NHEHCBFB_03443	1121115.AXVN01000032_gene379	0.0	1699.0	COG0500@1|root,COG3608@1|root,COG2226@2|Bacteria,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,3XZ0I@572511|Blautia	186801|Clostridia	Q	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA,Methyltransf_11
NHEHCBFB_03444	457412.RSAG_00183	4.31e-193	536.0	COG3773@1|root,COG3773@2|Bacteria,1VAUD@1239|Firmicutes,25B1B@186801|Clostridia	186801|Clostridia	M	Cell wall hydrolase	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2,LysM
NHEHCBFB_03445	1121115.AXVN01000032_gene381	0.0	973.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3XZ3J@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
## 3248 queries scanned
## Total time (seconds): 295.48436164855957
## Rate: 10.99 q/s