LOCUS       c00090_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NHEHCBFB_90.
ACCESSION   c00090_gnlPro..
VERSION     c00090_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 14:20:15
            Original ID  :: gnl|Prokka|NHEHCBFB_90
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 35697
            Orig. end    :: 58946
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[45697:48946]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1577..3034
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg90_41"
                     /sec_met_domain="FGGY_C (E-value: 7.2e-38, bitscore: 123.0,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 4.6e-80, bitscore: 261.4,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARNLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(3146..4081)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg90_42"
                     /sec_met_domain="LysR_substrate (E-value: 5.3e-33,
                     bitscore: 106.9, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 3.9e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAIEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFEHYIYQKEQ
                     LLLAVPKNYSVNTRLQEYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             4197..5621
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg90_43"
                     /sec_met_domain="Lyase_1 (E-value: 2.5e-94, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 9.4e-22, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             complement(5729..7414)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg90_44"
                     /sec_met_domain="FTHFS (E-value: 4.7e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg90_45"
                     /sec_met_domain="OKR_DC_1_C (E-value: 2.6e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 5.9e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEYLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg90_46"
                     /sec_met_domain="Spermine_synth (E-value: 3.3e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 4.9e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg90_47"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 4.1e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 3.5e-35,
                     bitscore: 113.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKIDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg90_48"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 4.7e-14,
                     bitscore: 45.3, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDMEELDRICDHIIFNS
                     TAQLKKFKEVCTGASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENGIRTLVLDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13284..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg90_49"
                     /sec_met_domain="PAD_porph (E-value: 6e-128, bitscore:
                     419.3, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGDFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTRED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14489..15367
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg90_50"
                     /sec_met_domain="CN_hydrolase (E-value: 1.2e-55, bitscore:
                     181.4, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGIYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             15595..16056
                     /locus_tag="ctg90_51"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIILLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             16258..20967
                     /locus_tag="ctg90_52"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGVDYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLRHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYDTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCSNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDELPSCLQLLEGQYAAETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTVTDIGLP
                     QGLVLAGGTQSMEVLGVQQQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     KDILNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVVQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVVDSSEKIPATGKAETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEMVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEAYVKAKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGITSGSGGSSYANSGGYTGGYGSYQGGSM
                     AGSSKTGDVRPFKMMAVLGLIGMGLLIGGVVIYRRTVSGKRNIKGMPRK"
     CDS             20964..21851
                     /locus_tag="ctg90_53"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNHADEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             22043..23134
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg90_54"
                     /sec_met_domain="Peripla_BP_3 (E-value: 5.8e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
ORIGIN
        1 ctgttttccg attcagcttt ctgaaaagag acgtgcagca atcaaggaaa cttataaagg
       61 tgaactttat gaatgtcctg taactgttga gaacgagaag gatatggaga aagctcttga
      121 agatgtaaac aaagcagagt gtaatgcgct ggttgttttc cttggaaact tcggacctga
      181 aactcctgaa actctgatcg cagagagatt tgacggacct tgtatgtatg tagcagcagc
      241 agaaggtgac ggtgatatga tcaacggcag aggtgatgct tactgtggta tgcttaactg
      301 ctcctacaac ttaaaaatgc gtcatctgaa agcatatatt ccggaatatc ctgttggaac
      361 agcagatgat attgcaaaga tgatcgctga tttcgtaccg gttgcacgtg cagtcatcgg
      421 tgtcagcaat cttaagatca ttactttcgg accacgtcca caggacttct tcgcatgcaa
      481 cgcacctatt aaaggcctct atgagctggg tgttgagatt gaagagaact cagagcttga
      541 tcttcttgtt tctttcaaag agcatgaaaa tgatcctcgt atcccggaag tttgtgcaga
      601 tatggccaaa gagatgggcg aaggcaaata ttatgctgac cttaatgtga aaatggcaca
      661 gtttgagctt acacttcttg actgggcaga ggctcataag ggagcaagaa aatacgttgc
      721 atttgctgac aaatgttggc ctgcattccc gtcacagttt ggatttgaac cttgctatgt
      781 aaatagccgt ctggtttcca gaggaattcc ggtatcctgt gaggttgata tctacggagc
      841 actcagcgag tacatcggac tttgcatttc caatgatgca gttacactgc ttgatatcaa
      901 caactctgtt ccacagtata tctatgatga agatattaaa ggaaaatacg attataagct
      961 tactgataca tttatgggat tccattgtgg aaatactcct gcatgcaaga tgtgtgattc
     1021 cagagctgtt aaatatcagc tgatccagca cagacttctt gagccggcag gatctgaacc
     1081 agacttcaca agaggaactc ttgaaggtga tatcgctgca tctgacatta cattctatcg
     1141 tttacagtgc aattccgagg gcgagctggt ttcttatgtt gcagaaggtg aagtactgga
     1201 tgtacctaca agatcattcg gtggtatcgg tattttcgca atcaaagaaa tgggaagatt
     1261 ctaccgtcac gtactgatcg agggcaacta tccgcatcat ggagcagtta tgtttggaca
     1321 ttacggaaaa gcattctatg aggtagtgaa attccttgga ctggatgtta agaagattgg
     1381 atacaaccag cctgcaggtg taagatatcc gacagagaat ccatggggtt aatgagacat
     1441 cagtaaaacg gattattaat gttcatgtga agtgaatgaa tctgaataca gaataaataa
     1501 actgacacta tattaaaggc atcccggggc tttgctctgg gatgtattag attagaaata
     1561 gaaaaggaga gcacttatgt attatattgg tattgacctt ggtacttccg ctgtaaaact
     1621 tcttcttatg gaagaatcag gaaaaatctg taacatcgta tccagagaat atcctttatt
     1681 cttcccacat ccgggctggt ctgagcagaa accggaagac tggtttgcgc agagtatgga
     1741 aggtatgaaa gagctgacaa aggatatcga cagagcgcag gtagcaggaa ttggttttgg
     1801 cggccagatg catggtctgg taacacttga caaggatgat aatgtgatcc gtcctgcaat
     1861 cctctggaat gacggacgta caggcgaaga gacagaatat ctgaatacag tgatcggaaa
     1921 agacaaactt tcacagtata cagcaaatat tgctttcgca ggcttcacag caccgaagat
     1981 cctctggatg cagaaaaatg agcctgagaa ctttaagaag gtagtaaaga ttatgcttcc
     2041 taaggattat ctggcatatc gtctgtccgg ttctttttgt acagatgttt ctgatgcttc
     2101 cggtatgctt cttcttgatg tgaagaaccg ctgctggtca aaagaaatgc tggagatctg
     2161 tggaatcaca gaagagcagc ttccgaaact gtatgagagt tgggaagtag taggaactct
     2221 gaaacctgag attgcgaaag aacttggatt cagtgagaat gtaaaagttg ttgcaggtgc
     2281 aggtgacaat gcggcagctg ctgtaggaac aggtacagtt ggtgacggtc agtgtaatat
     2341 ttctcttgga acatccggaa ctgtgtttat ttccagtaaa aactttggtg tggacgaaaa
     2401 taacgcactt cattctttct gtcatgcaga tggaagctat catctgatgg gatgcatgct
     2461 cagcgcagct tcctgtaaca aatggtgggc agaggagatt cttcagacaa aggatttcgc
     2521 agcagagcag gctccaattc agaagctggg agagaatcat gtattcttcc ttccatattt
     2581 gatgggagaa cgttcacctc ataataatcc tgatgcaaga ggtgtattct tcggaatgtc
     2641 catggacagc acaagagcag acatgacaca ggctgttctg gaaggtgttg cctttggtct
     2701 tcgtgattcc ctggaagttg caagaaacct tggaatcaag attgagagaa ccaagatctg
     2761 cggtggtgga gctaagagcc cactgtggaa gaagatcatt gcaaacgtta tgaacctgaa
     2821 ggttgatgtt ctggagaatg aagaaggacc gtccatgggt ggagctatgc tggcagcagt
     2881 aggctgtggt gcttacccgg atgtagaaac catcggtaag aaatttgcca aagttgttga
     2941 tacagtagaa ccggatcctg aactggttgc aaaatatgaa gagagatatc agaagttcag
     3001 aactctgtat ccggcgatga agccattgtt ctaatcgaat atctgcctga catactgggg
     3061 ttgttgtgct tatttagcac aacaacccca ttttgacgta catctgatga tgaccaatca
     3121 ccataaccta tttgattatg acatatcagg aaaatggcag cttcaggaat tcttccatgg
     3181 ctctgctgat atagcggcct ttcttccagt aaaaaaacac agtgcgttta ctgctctggc
     3241 cgggcagctt ataaaaaaca agttctgaat ttgttggaac tctggagagc agaagatccc
     3301 cgatgaaagt gatacccatt cccaaacatg caatattata ggcagtcatc tgctgatcca
     3361 ggcgaaatac tacagaaggc gaaaagtgat tttcctgaca aatggtaagt gcacgcttac
     3421 cggtatcatt atctgaacga agaataataa atggttcgtt ctcgaatttg tttaatggaa
     3481 cagaaggaat atgagaagaa cggaactgcc cgttccggat ttcctcaata ggaatctgat
     3541 attcctgcag tctggtattt actgaataat ttttgggaac cgctagaaga agttgttctt
     3601 tctggtagat ataatgttca aaaatctggt tatccagaat acagttatca atcaccagat
     3661 ctaactttcc ggcctggaga aactgggata gctttgctgt actttcttct acaagagaaa
     3721 tttgaacatg ggggaatttt tgggaaaaat cagcaataag gggaggcaga atccacgaag
     3781 aaaaaaagtt actgccacct acattaagag ttcctgtttt gagatttccc agatccagta
     3841 ggtagttttc gagattattt tcaatatcca tgactttttc aatagcctgt atataatgtt
     3901 ttccgacttc agttaactgt aaaggtttgg tacttcgatc aaaaatagga taaccaatgc
     3961 ggttttccac acgttttaca tttgcactta aagaaggctg cgaaatgaaa agagcagcag
     4021 cagctttgga aaagcttttt tccttgtata cctcatagat gtattccatt ccctgaaaca
     4081 tataaactcc tccgatatat aacttaaaca ctatatattt tataaaaata tatgtatttg
     4141 attatattat agcagagata tataatgagg gcaaatacat gggagggcga ataactatga
     4201 aaaaaacaga ctatcgtgta gaaagggatt ctattggtgt aaaggatatt ccggaagatg
     4261 tatattatgg agtacaatcc ttacgtgcgg ctgaaaattt ccacattacg gggctgaata
     4321 tgcatccgga aattattaac agtcttgcat acataaaaaa agcagcagcg ataaccaatt
     4381 gtgaggtggg gcttcttgag aagaaaaaag cacaggcgat tgtccaggca tgtgatgaaa
     4441 ttgtttcagg aaaattccat aatgaattta ttgtggatcc tgttcaggga ggagctggca
     4501 catctttaaa tatgaatgcc aatgaagtaa ttgcaaatcg cgcgattgag atactgggag
     4561 gaaaaaaggg cgattataca attataaatc ctaacgatga tgtgaattgt ggacagtcta
     4621 ccaatgacgt tattcctact gccggtaaaa tgacttctct tcgtttgttg cagaatctga
     4681 aaaaacagct tcttcgcctc tatgatgctc ttaatgaaaa agctacagag tttgatcaca
     4741 taataaaaat ggggcgtaca cagatgcagg atgcagtacc aattcgtctg ggacaggaat
     4801 ttaaggcata ttcggtagca atcatgcgtg atatccacag aatggataaa gcaatggatg
     4861 aaatgcggac tcttaatatg ggaggtactg ctattggaac aggaattaat gcagatgagg
     4921 gctatctgag aagaattgtt ccaaatctca ctgaaatatc gggaatggac tttatacagg
     4981 cttttgatct gattgattcc actcagaatc tggatccatt tgtagccgtt tccggtgctg
     5041 tgaaagcatg tgcggtaact ctttccaaaa tgtcaaatga tctccgtctg atgtcctccg
     5101 gtccacgtac tggttttggg gagattaatc ttccggcaaa acagaatggt tcctctatta
     5161 tgccaggtaa agttaatccg gttattcctg aagtagtgaa tcaggttgct tttaatatta
     5221 ttggtaatga tgttaccatt accatggctg cagaggctgg tcagctggaa ttaaatgcgt
     5281 ttgagccgat tattttctat tgcatgttcc agtctatcga tactcttggc tatgcagtcc
     5341 agacattggt ggataattgt attgtaggaa ttacagcaaa tgaagaaaga tgccgttatc
     5401 tggtagaaaa cagtgtaggt attatcactg caatcagccc ccatcttgga tatcagaagg
     5461 ctgcggatat tgcaaaaaag gcaattaaga caggcgaatc tgtaagaagt ctgattttga
     5521 aagaaaagct tatggacgag gatgaactta atcgcattct ggatccgatc catatgacgg
     5581 aacctggtat ttccggaaaa gattatctta taaaaaaata agaaaaaaac aggcgggaaa
     5641 atcttcccgc ctgtaaaatc gtctggacac atatcatata taaatatgat ttttatattt
     5701 ttgaattatt cgattgattt caaccggatt agaacagacc tgtaatctta cctgtctcgt
     5761 ctacgtcgat tctctcagca gccggaactt taggaagacc tggcattgtc atgatctcgc
     5821 ctgtaagagc tacgatgaat cctgcaccag cggaaatctt caggttacgt actgtaactt
     5881 cgaagtcagt aggagcaccc agtttggtct ggtcatctgt taagctgtac tgagtcttag
     5941 ctacacagat tgggcagttg ccgaatccaa gagcttctaa ctgtttcgcc tgtttctgag
     6001 cgttagctgt cagaactact ttcttaccgc catatacttt ctgaacgatc tggttcagtt
     6061 tgtcttcgat agaaccttcc agttcatatg cataggagaa gtcgtttggt tcttcaacaa
     6121 gacggataac ttcttctgca agtttgattc cgccttcgcc gccttttgcc cacacttcag
     6181 aaagagcaac gttaacgccc agttctttac atttagcttc tacaaagtca agctctgctt
     6241 ttgtatctgt agggaatgcg ttgatagcaa caacacatgg aagtttgtat acgtttttga
     6301 tgttggaaac gtgttttaac aggttcggga tacctttttc aagagcttcc aggttttcat
     6361 tgttaaggtc agctttagca acgccgccgt tgtatttcag ggcacgtact gtagctacga
     6421 ttacaactgc gcttggtttt aaaccagcca tacggcattt gatatcaagg aatttctcag
     6481 caccaaggtc agcaccgaaa ccagcttctg tgattgcata atcagcaagc ttcatagcca
     6541 tctttgtagc tgttacagag ttacatccat gagcgatgtt tgcgaatggt ccgccatgta
     6601 cgattgcagg aacgtgttcc agagtctgta caaggtttgg tttcagagca tcttttaaca
     6661 gggctgtcat agcgccttct gcgtgaaggt cacctgctgt tacaggtttc tgctcggaaa
     6721 cttttccgta tgtatatccg atgatgatct tggataatct ttctttcagg tctttgatgt
     6781 cgcttgcaag acagagaact gccatgattt cagatgcaac tgtgatgtcg tatccgtctt
     6841 cacgaggcat accgtttgtc tttccgccaa gaccatctac tacgttacga agctgacggt
     6901 cgttcatatc tacacatctt ctccatgtga tcttacgtgg gtcgatgttt aatgcattgc
     6961 cctggaagat atggttatcg atcatagctg ccagtaagtt gttagctgcg ccaatggcat
     7021 ggaagtcacc tgtgaagtga aggttaatat cttccatagg aacaacctgt gcatatccgc
     7081 cgcctgctgc accacctttt acaccgaata ccggtcctaa ggatggctca cgaagagcta
     7141 ccataacact cttgccaagt ctctgcatac catctgcaag acctacagta gtagtagttt
     7201 taccttctcc tgctggagtt gggttgatag ctgtaacgag gattaatttt ccgtccttct
     7261 tatcactttc tttcagaaga ttgtagtcga tttttgcttt gtattttccg tactgctcca
     7321 gatatttgtc gtcaatacct gctttctctg cgatctgagt aattggaagc atctcgcatt
     7381 cctgtgcaat ttcaatgtct gatttgaatc ccataattgt ttttctcctt tcgtttccgc
     7441 ataacatgaa aaacttctgt tgctgttcac tctgcgatca gcaacaatta ttaattgaaa
     7501 gaagtattgg ccggtctgcc tggtattcct gatttctgcc ctgaaagtta taaaaaaagg
     7561 ccagtatctg aatatttcaa atactgccca gacggtcggc tcccacaaac ctccgactcc
     7621 acgtggtttg cactccactc tttccgtcag tactcgaagg ttctttcaat tgatgaatac
     7681 aatatatcat tttgagaaaa aaatgtcaag aaaatttttg ttgaaacgtc aaaaaatgtg
     7741 agtaaactgg ataaaagttg tgcaaattga taagagaaga gaatcgtaat ccctggtaat
     7801 gaaagaaaat acgttttctc aagggaagaa attgttaaaa aataaacaca gttttccctg
     7861 acaaatgaag aaaatataaa aagcgggtaa agactgtgca aaatatggaa aatggaattg
     7921 acaacagttc agaagatatg ttattctcat ctttagtatg aaaagacact atcgttttca
     7981 tgcaaatatt tgctcacatt cagagacagt ttctgaatgt taagccatac ggacaggcgg
     8041 ggcagttgcc gggtgggaga caccacatta ttgattgagt tagaagctca aattttataa
     8101 gttgattact ttataataat cagtgcgtaa gcacacatca tcttgtgaaa cggtcaataa
     8161 gagcatagca tatatttgcc agcgattgaa gacgacagca gtcatgaata tttcagaata
     8221 cgggaacagg cacaggatac agacggattt atacgggaaa tccggtcagt atataaagag
     8281 acagagcctg agaaattcta tagatcatga gagaagcaga tggtgaatga acttatctgc
     8341 ttcttttttt gtgcagatat agcaaatata aaggatatgg ttggagataa acgctttgcg
     8401 gggatgtgtc tcacatgcgt tcgacttgaa tatatagaga aataattgaa tcattgtgcc
     8461 ggtttgaggc agtatacaat tgctgaatga tagaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccggagctt gcacagttgc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgctggac aatctctgcc acccggtttc ggtgatcaga gaagcggagg
     8761 agcttgcagc agatgctttt ggcgcagcgc atgcattcct tatggtagga ggaaccacat
     8821 ctgcagtgca gagcatgatc ctgtctgtct gcaaggcagg ggataagatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg cggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgcg cagctgggca tttcccttgg catggaagtc agtcaggtgg
     9001 agaaggctat ggatgagaat ccggatgcgg tggcagttct tgtaaataac cctacctatt
     9061 atggaatttg ttcggatctg cggactatcg taaagaaggc tcatgcaaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtatccg
     9181 gaatggcggc aggtgctgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agcgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggcactcagg ggagaggaat cctttgaaaa ggttgcaggg atggcgcagt
     9421 atgccagaga ggagatcaat gagatcggcg gttattatgc atatggtatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc tatttataca ctgggaaatg
     9541 ggctggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccatcgg agacaggctt caggatattg
     9661 agagactggt aggggcattg gctgatattg aacgtctgta taagaaggac agcacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacagg cggcaggcag gatcagtggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctgggga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtagaata tcttcaggtt ctgaaagggg gtatctgatc atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttgggagat ttgtggctct
    10141 ggacggtgag atcgtattct ctgataaaga tgaatttatt tatgatgaga tggtcacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg atcatcggcg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agcattgatg tggtggaatc
    10321 cgataaaatg tttgtggatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttataa ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gataatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggtggg gtagcttcag tggcaattcg caaatgctgt
    10921 cagaatagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaagatagat
    11041 gcggataatg cagcagaggt cgcagaattg atcagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctatgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggcttatg atgagaaatt taaggaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgct tatgccctga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaacggc ggtgatcatg gatatccttt tgccacaaac
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct acgattttcc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa aaatattccg
    11641 ggagtacaga ggatccgttt ctttatgaca ttcggacaga gttatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaatgg acaggagatt
    11761 gtgccgatcc agtttttgaa agctcttctg ccggatcctg catctctggg cccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gacaggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttccg gctttgccct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatggag gaactggatc ggatctgtga
    12421 ccatattatc tttaattcca cagcacagct gaaaaaattt aaagaagtgt gtaccggagc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag ggggatcatg cgatctatga
    12541 tccctgtgcg ccgggttcca ggctgggggt taccagagag aactttgacg gggaatgtct
    12601 gaaatggatc gacggactgc attttcatac gctctgcgaa cagaatgcgg atgacctgga
    12661 gaaaacattg caggcggtag aggagaagtt tggagaattt ctgtctgagg tttcctggct
    12721 gaatatgggc ggcggacatc atattaccag agaggattat gatgtaaagc tcctggaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatggaat
    12901 cagaacgctg gttctggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgcctgg caggagatgt gatcggagat tattcctttg acagagagat
    13081 ccggatcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaac ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taagagccgg ctttcctgat atctgccggg
    13261 ttatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcacaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaaggtgtat atgctggttt ccaaagctca gatggagaat gcaaagaatc
    13501 agcttgggaa tgtttccggt gtgactttgc tggaatgcga gacagatgac gcctgggcca
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggagga gactttgacg ggctttaccg gaactgggag aaggacgaca
    13681 gggtggctgc ctttatctgc aggactcttg gttgtccatg tctggatgcc agaccttttg
    13741 tgcttgaggg cggttccatc cattctgacg gagaggggac tctgatcgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaaggcc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtcttt ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccgg gaagatgtgg atggctttgt gtttgaagag ggagaagacg
    14161 aacgggaagc aggagaacgg atggctgcca gttatgtgaa tttttatatt tccaatggag
    14221 ggatcatcct tccacaattt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc tgaaagaagg atttatccca ttgatgccag agccatcatt gtcggcggtg
    14341 gaaatattca ctgtattacc cagcagatcc ccggaaaaaa tatctgaccc tgatgcagaa
    14401 aaactttgag agtcatgtgt ttgagggtta tacctgaaag ttatgaaaaa acttacttat
    14461 gtaaacagga gcaggaggaa cagacaggat gagaaatgta acagtggcag cagttcagat
    14521 gaaatgcagt aaaagtgtgg agaaaaatat tgcccatgca gaggaactgg tgcgtcaggc
    14581 agcagcaaag ggagctgaga ttgttcttct tccggagctt tttgaacggc cctatttctg
    14641 ccaggagcgc agatacgagt attatgaata tgcgcagact gcagaggaaa accctgcagt
    14701 gcgtcatttc agcagggtag cggcagagct ggggattgtg attccggtca gcttttatga
    14761 aaaagaggtc aataatactt ataacagcgt tgcggttctg gatgcagatg gaaagaatct
    14821 cggtatttat cggaaaacac atattccgga tgaccattat tatcaggaaa aattctattt
    14881 cacaccggga gataccggct ttaaggtttt tgataccaga tttggaacca ttggagttgg
    14941 aatctgctgg gatcagtggt tcccggaaac ggcaagatgt atggcactgc agggagcaga
    15001 gcttctcttt tatcccactg ccatcggaag tgaacccatc ctggaatgtg acagcatgga
    15061 acactggaga agatgtatgc agggacacgc tgcctccaac ctgatccctg tgatcgctgc
    15121 caatagaatc ggtgaggaaa cagtagagcc atgtccggaa aacggaatgc agaaatctgc
    15181 tcttaatttt tacggctctt cttttatcac agacaacaca ggcgctctct gtgcagaact
    15241 gcccggaggg gaagaggggg tgcttgtaag cacttttgac ctggatgcat taaaggcaga
    15301 cagactgaac tggggacttt tcagagaccg cagaccggag atgtatgcaa aaattgtcgg
    15361 gaaatgacat acgagccaaa cttccattgc cgcaggcaat ctggaatgaa ttttggctca
    15421 gttactgaga acggagtgaa cagtaactga gtttataaga atttcataaa aagtttatga
    15481 ttatattagt tgctacctgc ggtatatatg gtaaaataag agtacgaacg ttactgataa
    15541 cggagagagc agtagagttt tgatatgtat ttctggcaaa atggagtgta gaagatgaac
    15601 agaaaagaat ttttggaaat cctgagaagc cagcttgccg ggcagatgca ggaaggcaaa
    15661 gcagcggcac atatcaggta ttatgaagat tatatacagt ctcaggtacg tggcggacgt
    15721 tcagagcagg aggtactgca ggaactggga gatccacatc tgatagcaaa aactctgatc
    15781 gatacagatg atggaagtac acaggaagat tacggagagt attcttctta cggaagcagt
    15841 tatggcaatg agacagagct tcctcatcag caggagaaaa gatggaaaaa agtaatcgat
    15901 ctttctacct ggcatggcag ggctgttgtt attgcagcag cggctgttat aattatttta
    15961 ctgatactga taatcggagt tgcgattccg ttttttatta ttcttgcaat tattctttat
    16021 tttctttcat ggctgaagaa aagaaatgat caatgaaaat ctgtgcaggg tttcagaaaa
    16081 ggaaccctgc gcagaatctt aaaatcttaa gtgtaaacgt tcttgtttca cgatattaat
    16141 tccccttgaa tatttataat catacatttc aacttatttc tattctttaa tcctgcctgg
    16201 tgcagggaaa aatcccacat tcatttttat attttttgtt cggaaaggag acggaaaatg
    16261 aaacacaatt tcaaactgaa agaacgcctt ggagctttgc tgcttgcaat gctttttatt
    16321 ctgcaggcaa ttctggggct tgtgcctgtc tgcgtaactc aggcggcacc gttaactgta
    16381 gaaacatggg acagtgacaa ggtggtagat tatggttatc gctttaacat gaagtttcag
    16441 cccggaatta ccacatatga atcttttggg tgtgataatc tggacaggga agctttttca
    16501 gacaatggaa aaagcgaacg cgacacagag tgcgttcgtg taggagtgga ctataaagcc
    16561 ggaagcgcag ggatgcgtta taacaatgta ggaaaagatg gaaatggaaa tattgttgat
    16621 gtcagactca ttcttgtggg agtagagaat gcagaacccc gttatgatct gcgcactgca
    16681 gaatcgattg ttcagaataa aggcggagct acgtttgcat ggaaagataa tgaagcttat
    16741 ccaatggttg gcttttccaa aaacagtatc ggtgtattta tttattctgt aggatacgca
    16801 aaggttaagt ttcagtttct gaggcatgga acagaagaaa cactgccgat cagtggccat
    16861 ggaaccatac gtgatattga tgcgggacag ggagtccgta ttccgtcaga cagcagtctg
    16921 gataatgcat atgttctgaa aaacaatgat tatctgacgg tagatggaaa ttctgtaagc
    16981 tcaccccttg gttccgttga gccggatgat ccgagaggat ggctgaatct tttttatgat
    17041 acagataatt ttacggtaga attctgtcat cagttcagac tggataaatg ggataaaagt
    17101 cgtgaagatg ccattgcaaa agccggttct caggaaagat gggcagagat tacaagaaat
    17161 aaatatctgg atccatcagg caacagttat tgttcgaact ttaaaggaca gaaatactgc
    17221 aaagcatatg catattttga ttttacatcc tattgtttcg gtgatgttga gatgaaaaaa
    17281 gcgcctgaga aacgtgtggg agaggcaaac tgtacatggg aacaggcagc tgccgcatca
    17341 aaagaaaaac cttttggcat tcgtcaggga caggaatttc agtatatgat ccgggcggag
    17401 gtgacaccca atagactgaa atcctttgtg gtacaggata tacttgagga ttgtcttact
    17461 atagaggatg catcaaaagt cagtattgtg aatgatgcag ggcagacagt gacagactgg
    17521 tttgatgttg ctgttgaagg acagaaagtg acctgcaggg ccaaagcaga gagccttcag
    17581 gatgaagcat ttacagataa tcagacttac acatttactt taaaagtacg ccagagaccg
    17641 gaatcagaaa ttaacatttc aaaatacctt gcagaggatg gatacagtat tcttgtacca
    17701 aaccatgcat ccatgagtta tgaacgtaca aacggaagcg gagatacaat ggatacggaa
    17761 acagtgtggg taaagggtgt gattccaccg gaactggaag taaagaaaaa tacttctcag
    17821 tatgaatgga aaacgggaga tatcatagat tatgaggttc tggtttctca gacaaaacag
    17881 gatgtaaaag cagtaaatgt tgttattaca gacgagcttc catcatgtct gcagcttctg
    17941 gaagggcagt atgctgcaga gacaagtcag ggaggtgaga actgtacgct taccggacag
    18001 ggagaaaatg gatggaaagc agagtgtccg tccctgaagt atggagagac gatcacaatc
    18061 cgttttaaat gtcaggcatc tgcggattcc aatggacagg aatgggaaaa tattgtgact
    18121 gcaacagcgg ataatctgat caatcctgag acaggagaac aggaatccag aaaggatatg
    18181 gcagaagtat ggccgaacag tccacagctt gaaattgata aaacagcaga caaatatgaa
    18241 tggcaggcag gagagcaggt agcttaccgg attgtggtga ataatgtgac ggcaggaaca
    18301 attgcaaaag atgtaactgt tactgatatt ggtctgccgc agggactggt tctggcaggt
    18361 ggtacacaga gcatggaagt actgggagtt cagcaacagg taaactatcc cgtaccggat
    18421 aagaaaacag gacaggcata tgaagcgaga cctgtggatt ctcagttgaa tgcagatgag
    18481 aacggatttt ccttttattg ttcttatgta ccatacagtc agcctgtaac gattattttc
    18541 cattgtatcg cacaggaaga ggcaaatgga cacgaaagcg taaatgcagc aactgtaaaa
    18601 gctgctaata cagatgagag atctgatgat gcagaagtat atgtaaattc aggagaattc
    18661 tggattgaga aatctgcaga tcattatgaa tggcaggtcg gagaacaggt acagtacaat
    18721 gtggtggtgg agaataaaaa agcaggtaca gtggcccgga acgtaactgt ctgggatacc
    18781 ggtatgccgg caggacttgc gctttcatcg gcagaggatg tatcggtaag cggaatccca
    18841 cagaatatta cgcagctgac agcagggacc aaagatattt tgaaccagct caatccggaa
    18901 ttttataatg agacatcaga gaaaccggtg aattatgaat ttcttcagga gggaagcgga
    18961 tggagactga acatttcaga tcttccggca aatactccgg ttatgatttc tttcctttgc
    19021 acagttacgg aagcggcaaa tggaatggaa agcattaatg ttgccaatgt gcaggcgcag
    19081 aatgcccctg tttcacagga tgacgcagaa gtgtatgtaa atacagcagt tctttctatt
    19141 gagaaaagtt ttcagaatcc atatctggca gccggggacg gacgtgcgga aaatgaattt
    19201 cgggtaggag aacaggtgaa ttatcaggtt acggttaata atcttcagaa gggatctatc
    19261 gcaagaaatc ttgtgatcag tgatctttcc cttcctgaag ggctggctct ggacggagct
    19321 gaagatgctg ttactgtaag cggtgttccg gctgttgttc agaatccggt ggcaggaact
    19381 gatgatgcag gaaatcagct gaatccggaa aattataaag aaacagtgga aaaaccggtc
    19441 agctgtcagg ttacacgtca gggaaccgga tggatcgtga cgatttcaga tcttccgtat
    19501 cagacacctg tgactgttaa tttccgctgt actgcgcagg aaagcgtaaa tgggatggag
    19561 atcgtaaata cagcacaggc gtatgcagat aatgcacaga aagtaaagga ctcctcaaaa
    19621 atctgggtga actcgcctgt tcttaaagta gagaagacga cggacaaacc attttacaaa
    19681 tatggtgata ttattacata ccgcattgtc ctgacacagg agcagaccgg atgtgtggcg
    19741 cgtaatgtta ctttgcagga tgtgatcgat actcagggag tacgtcttct gaaggattcg
    19801 gtgattctga tggatgagaa aggaaatgtg gcagatgctg atgtacagat taatgatgat
    19861 aatactttcc tgatgtcaac aggcaggaca ctggtcaggg atagcagata tagtatctgc
    19921 gataatgata aaggcggtct ttttgagcag gtaatgtata atcctctgga ctgtcaggaa
    19981 cagaaaagta tgatcgtgga atatcaggca gcagtgattg atgcagccct ggcaggacag
    20041 aaggtgcaca atactgcagt tgtagacagc agtgaaaaga tacctgcaac cgggaaagca
    20101 gagacagagg tacacagtcc gattctggaa attgtgaagg aatcagataa gaaagagtat
    20161 gcgtccggtg agaaaggata ctataaactg acagtaagac aactgcgtga ggatgtcaca
    20221 gatcagaata ttgttatcga agataaactg gaaacccaag gggcttccat tgtaaaagac
    20281 agcatttttg tgaaaaaaaa cggtatagaa ctgaaagatg ccaaaataga ggcagatgat
    20341 acaggatttg taattcagac aggagcatcg ttgtcagata tggataaaat tgaagtctgc
    20401 tatgaaatgg tatttaaaac agaaagcaca gagcctgaaa aaattgtaaa cacagcgaaa
    20461 gcaagaggtg atatttcacc ggaaattact gcacagcagg aggcatatgt gaaagcaaaa
    20521 gcagaaccga ctgccacacc aacaccgtct gcaacaccga aaccaacaga aacaccaaag
    20581 ccgacagaga caccaaaacc tacagaagta ccgaaaccga cggagcagcc aaaagccaca
    20641 ccaacaccat ctgtaccggg aacctgcccg aaaatgactc ctgtaccgac gaaagcaccg
    20701 ttagcatctt acaatggtgg aaataatgga ggcataactt ccggaagcgg aggcagcagt
    20761 tacgcaaatt cgggtggata taccggtgga tacggaagct atcagggtgg ttccatggca
    20821 ggaagttcta aaacaggaga tgtcagaccg tttaaaatga tggctgttct tggccttatc
    20881 ggaatgggac tgctgatagg aggtgtggtg atctacagaa gaactgtttc cgggaaaaga
    20941 aatataaagg gtatgccgcg gaaatgaaaa aactcagaac atttgcagta agtatgatca
    21001 tagcagcaat tgggcttctt atatattgtg ccggcttcta tataaaaagt tatgaacaga
    21061 atcttgcagc aaggcaggaa tatgcagagc tttcccaaat ggcaggggtg aagaacagag
    21121 aaggtgccgg attattggca gatggcaaaa aaactgatga agacagcagt acaaaaaaca
    21181 gtgaaaaaaa acgcaggaaa aaacagagaa gatcttctga atcaaaaaac aaaaaccatg
    21241 cagatgaaat cagggaatcc ttcgggattt cctgggaaaa tttaagaaag atcaactctc
    21301 agacagttgc ctggattact gtcccgggag ccgatatttc ttatcctgta gttcaggcgg
    21361 cggatgatga atattacctg aaacataatt tcagaggaga ggaagatctg tttggatgta
    21421 tttttctgga acatgacata aaaaagaatt ttacagattc ccacagtatt ctttacgggc
    21481 ataatataga aggtaatatg atgtttgcaa atctgaaccg ttatgaacaa cctgaatttc
    21541 tgaaaaaatg tcctgaaatt gagatcacaa caccaaaaag aaagtttctg tacaaaattt
    21601 tttctgtgga acaggcatct tcccaaagcc cggcatttga atatggatac aagttatcca
    21661 gtcctgcata caggagacaa ttatctatat tgaaaaataa ttccatgtat gacacaggag
    21721 tagagcctga tgaaagggag agaatggtga ctctgatcac ctgtaattca cgtctggata
    21781 aagaaatacg tatggcggta catgggattt gccatgaatg ttatggtata gaaaaagctg
    21841 agccgaagtg atgttgaaat caatcggata ttggtaactt tcgtaaagga tgaactgtta
    21901 ctgtttacat atcactatcc ctcgaggtgt tttggaaaaa actaatgaaa aatctctcaa
    21961 tattttgtat aatttatgca taaaaaacaa cttgttcgta cgtgcgtaca agttgtatcc
    22021 taaatacagg agggaagaag acatgacaga taatggaaag ccgaaatatt tctcactgat
    22081 ggaacagctc agaagtgata ttatgtcagg agctatccga ccgggagaga agcttccttc
    22141 agaaaacgag ctttcacaga aatattccct gagtagacat acagttcgta aagcactggg
    22201 aatcctggag caggacggat atgtagaggc atttcacgga agaggtactt attgctctga
    22261 gaatatgcgc catataaaga attcaaagaa tattgcggta gtgaccacat atatttctga
    22321 ttatattttt ccgagactga tacagggaat ggataatgtc ctttcagaaa gcggttacag
    22381 tattatcctg aaaaacacag caaacagcag acagaaggag gccagatgtc tggaggaact
    22441 tctgaagaaa gatattgatg gactgatcat tgaaccaagc aaaagtgaga tgatctgtaa
    22501 acacagaaat ctttatcaga atctggataa atttgaaatt ccgtatgtgt ttattcaggg
    22561 aatctattca gaaatgaggg ataaacctca tattcttatg gatgatgcac agggaggcta
    22621 tcttgtaaca aaatatctgc tggaactggg acataaaaag atcaagggtt tctttaaggc
    22681 agacgatatg cagggactgg agcgccacaa gggatatgtg aaggccttac aggagtcagg
    22741 gattgcctat gatcctgatg atgttgtctg gtttcataca gaggacagga aagtaaaacc
    22801 tgcactgatg gcaaaagaaa tggtacagag cggacagctt ccggatggaa tcgtctgtta
    22861 caatgatcag attgctgttc aggttatgga agaactggag aaaatgggag tcaggatacc
    22921 ggatgatatt tccattaccg gttatgacaa ttcactgtat gctcagcgag gaagcggaat
    22981 cacaacgata gctcatccgc aggaaaagct gggagaaatg gcagcagagc ttatacttga
    23041 gaagatcaac ggagttcctg aagaagaaag taaggttgaa agactgattt atccggaact
    23101 gatcatacgg ggatcatgca gaaaaatatt gtaaacaaat gaaataaata aaaaataaga
    23161 ataaatccag gaggaatttt atcatgaaaa caggaagaaa ctataagttc tggttttgta
    23221 caggttcaca ggatctttac ggagatgag
//
