LOCUS       c00109_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OHHHLHLN_109.
ACCESSION   c00109_gnlPro..
VERSION     c00109_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 18:09:05
            Original ID  :: gnl|Prokka|OHHHLHLN_109
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 66601
            Orig. end    :: 89850
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[76601:79850]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="2"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(155..1246)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg109_61"
                     /sec_met_domain="Peripla_BP_3 (E-value: 6.1e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
     CDS             complement(1438..2325)
                     /locus_tag="ctg109_62"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSK
                     MAGVKNRAGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             complement(2322..7019)
                     /locus_tag="ctg109_63"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAATSKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDELPSCLQFLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARSVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVAEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLNVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGETETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEVVFKTESTEPEKIVNTAKA
                     RGDISPEIAAQQEVYVKTKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGNGGSSYGNSGGYGSYQGGSMAGSS
                     KTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             complement(7222..7683)
                     /locus_tag="ctg109_64"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGKAVVIAAAAVIIVLLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             complement(7883..8761)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg109_65"
                     /sec_met_domain="CN_hydrolase (E-value: 1.2e-55, bitscore:
                     181.4, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGIYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             complement(8863..9966)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg109_66"
                     /sec_met_domain="PAD_porph (E-value: 3.1e-127, bitscore:
                     417.0, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGVSEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGTFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTQED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             complement(10001..11122)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_67"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.2e-14,
                     bitscore: 47.2, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKINQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTGASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYNVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIQIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             complement(11112..12392)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_68"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 4.3e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 2.1e-35,
                     bitscore: 114.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKK
                     KIESTTKTKIETAKVDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYNEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             complement(12389..13249)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_69"
                     /sec_met_domain="Spermine_synth (E-value: 3.5e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 5.2e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             complement(13252..14709)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg109_70"
                     /sec_met_domain="OKR_DC_1_C (E-value: 4.8e-13, bitscore:
                     42.4, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 6.2e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQTAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEYLQVLKGGI"
     CDS             15836..17521
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg109_71"
                     /sec_met_domain="FTHFS (E-value: 4.9e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             complement(17630..19054)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg109_72"
                     /sec_met_domain="Lyase_1 (E-value: 2.6e-94, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 9.8e-22, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             19170..20105
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg109_73"
                     /sec_met_domain="LysR_substrate (E-value: 3.6e-33,
                     bitscore: 107.5, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 4.1e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFERYIYQKEQ
                     LLLAVPKNYSVNTRLQKYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             complement(20217..21674)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg109_74"
                     /sec_met_domain="FGGY_C (E-value: 7.6e-38, bitscore: 123.0,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 4.8e-80, bitscore: 261.4,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARNLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
ORIGIN
        1 aacaatgatt ctggaatgct cagcaacttt tcttaagcac tcatctccgt aaagatcctg
       61 tgaacctgta caaaaccaga acttatagtt tcttcctgtt ttcatgataa aattcctccc
      121 ggatttattt ttatttttta tttatttcat ttgtttacaa tatttttctg catgatcccc
      181 gtatgatcag ttccggataa atcagtcttt caaccttact ttcttcttca ggaactccgt
      241 tgatcttctc aagtataagc tctgctgcca tttctcccag cttttcctgc ggatgagcta
      301 tcgttgtgat tccgcttcct cgctgagcat acagtgaatt gtcataaccg gtaatggaaa
      361 tatcatccgg tatcctgact cccattttct ccagttcttc cataacctga acagcaatct
      421 gatcattgta acagacgatt ccatccggaa gctgtccgct ctgtaccatt tcttttgcca
      481 tcagtgcagg ttttactttc ctgtcctctg tatgaaacca gacaacatca tcaggatcat
      541 aggcaatccc tgactcctgt aaggccttca catatccctt gtggcgctcc agtccctgca
      601 tatcgtctgc cttaaagaaa cccttgatct ttttatgtcc cagttccagc agatattttg
      661 ttacaagata gcctccctgt gcatcatcca taagaatatg aggtttatcc ctcatttctg
      721 aatagattcc ctgaataaac acatacggaa tttcaaattt atccagattc tgataaagat
      781 ttctgtgttt acagatcatc tcacttttgc ttggttcaat gatcagtcca tcaatatctt
      841 tcttcagaag ttcctccaga catctggcct ctttctgtct gctgtttgct gtgtttttca
      901 ggataatact gtaaccgctt tctgaaagga cattatccat tccctgtatc agtctcggaa
      961 aaatataatc agaaatatat gtggtcacta ccgcaatatt ctttgaattc tttatatggc
     1021 gcatattctc agagcaataa gtacctcttc cgtgaaatgc ctctacatat ccgtcctgct
     1081 ccaggattcc cagtgcttta cgaactgtat gtctactcaa ggaatatttc tgtgaaagct
     1141 cgttttctga aggaagcttc tctcccggtc ggatagctcc tgacataata tcacttctga
     1201 gctgttccat cagtgagaaa tatttcggct ttccattatc tgtcatgtct tcttccctcc
     1261 tgtatttagg atacaacttg tacgcacgta cgaacaagtt gttttttatg cataaattat
     1321 acaaaatatc gagagatttt tcattagttt tttccaaaac acctcgaggg atagtgatgt
     1381 gtgaacagta acagttcatc ctttacgaaa gttaccaata tccgattgat ttcaacatca
     1441 cttcggctca gctttttcta taccataaca ttcatggcaa atcccatgta ccgccatacg
     1501 tatttcttta tccagacgtg aattacaggt gatcagagtc accattctct ccctttcatc
     1561 aggctctact cctgtgtcat acatggaatt atttttcaat atagataatt gtctcctgta
     1621 tgcaggactg gataacttgt atccatattc aaatgccggg ctttgggaag atgcctgttc
     1681 cacagaaaaa attttgtaca gaaactttct ttttggtgtt gtgatctcaa tttcaggaca
     1741 tttttttaga aattcaggct gttcataacg gttcagattt gcaaacatca tattaccttc
     1801 tatattatgc ccgtaaagaa tactgtggga atctgtgaaa ttctttttta tgtcatgttc
     1861 cagaaaaata catccaaaca gatcttcctc tcctctgaaa ttatgtttca ggtaatattc
     1921 atcatctgcc gcctgaacta caggataaga aatatcggct cccgggacag taatccaggc
     1981 aactgtctga gagttgatct ttcttaaatt ttcccaggaa atcccgaagg attccctgat
     2041 ttcatctgta cagtttttgt tttttgattc agaagatctt ctctgttttt tcctgcgttt
     2101 tttttcactg ttttttgtac tgctgtcttc atcagttttt ttgccatctg ccaataatcc
     2161 ggcacctgct ctgttcttca cccctgccat tttggaaagc tctgcatatt cctgccttgc
     2221 tgcaagattc tgttcataac tttttatata gaagccggca caatatataa gaagcccaat
     2281 tgctgctatg atcatactta ctgcaaatgt tctgagtttt ttcatttccg cggcataccc
     2341 tttatatttc ttttcccgga aacagttctt ctgtagatca ccacacctcc tgtcagcagt
     2401 cccattccga taagtccaag aacagccatc attttaaacg gtctgacatc tcctgtttta
     2461 gaacttcctg ccatggaacc accctgatag cttccgtatc cacccgaatt tccgtaactg
     2521 ctgcctccgt ttccggaagt tgtgcctcca ttatttccac cattgtaaga tgccaacggt
     2581 gctttcgtcg gtacaggagt cattttcggg caggttcccg gtacagatgg tgttggtgtg
     2641 gcttttggct gctccgtcgg tttcggtact tctgtaggtt ttggtgtctc tgtcggcttt
     2701 ggtgtttctg ttggtttcgg tgttgcagac ggtgttggtg tggcagtggg ttctgctttt
     2761 gttttcacat atacctcctg ctgcgccgca atttccggtg aaatatctcc tcttgctttc
     2821 gctgtgttta caattttttc aggctctgtg ctttctgttt taaataccac ttcatagcag
     2881 acttcaattt tatccatatc tgacaacgat gctcctgtct gaattacaaa tcctgtatca
     2941 tctgcctcta ttttggcatc tttcagctct atgccgtttt tcttcacaaa aatgctgtct
     3001 tttacaatag aagccccttg ggtttccagt ttatcttcga taacaatatt ctgatctgtg
     3061 acatcctcac gcagttgtct tactgtcagc ttatagtatc ctttctcacc ggacgcatac
     3121 tctttcttat ctgattcctt cacaatttcc agaatcggac tgtgtacctc tgtctctgtt
     3181 tccccggttg caggtatctt ttcactgctg tctgcaactg cagtattgtg cactttctgt
     3241 cctgccaggg ctgcatcaat cactgctgcc tgatattcca cgatcatact tttctgttcc
     3301 tgacagtcca gaggattata cattacctgc tcaaaaagac cgcctttatc attatcgcag
     3361 atactatatc tgctgtccct gaccagtgtc ctgcctgttg acatcaggaa agtattatca
     3421 tcattgatct gtacatcagc atctgccaca tttcctttct catccatcag aatcaccgaa
     3481 tccttcagaa gacgtactcc ctgagtatcg atcacatcct gcagagtaac attacgcgcc
     3541 acacatccgg tctgctcctg tgtcaggaca atgcggtatg taataatatc accatatttg
     3601 taaaatggtt tgtccgtcgt cttctctacg ttaagaacag gcgagttcac ccagattttt
     3661 gaggagtcct ttactttctg tgcattatct gcatacgcct gtgctgtatt tacaatctcc
     3721 atcccattta cgctttcctg cgcagtacag cggaaattaa cagtcacagg tgtctgatac
     3781 ggaagatctg aaatcgtcac gatccatccg gttccctgac gtgtaacctg acagctgacc
     3841 ggtttttcca ctgtttcttt ataattttcc ggattcagct gatttcctgc atcatcagtt
     3901 cctgccaccg gattctgaat aacagccgga acaccgctta cagtaacagc atcttcagct
     3961 ccgtccagag ccagcccttc aggaagggaa agatcactga tcacaagatt tcttgcgata
     4021 gatcccttct gaagattatt aaccgtaacc tgataattca cctgttctcc tacccgaaat
     4081 tcattttccg cacgtccgtc cccggctgcc agatatggat tctgaaaact tttctcaata
     4141 gaaagaactg ctgtatttac atacacttct gcgtcatcct gtgaaacagg ggcattctgc
     4201 gcctgcacat tggcaacatt aatgctttcc attccatttg ccgcttccgc aactgtgcaa
     4261 aggaaagaaa tcataaccgg agtatttgcc ggaagatctg aaatgttcag tctccatccg
     4321 cttccctcct gaagaaattc ataattcacc ggtttctctg atgtctcatt ataaaattcc
     4381 ggattgagct ggttcaaaac atctttggtc cctgctgtca gctgcgtaat attctgtggg
     4441 attccgctta ccgatacatc ctctgccgat gaaagcgcaa gtcctgccgg cataccggta
     4501 tcccagacag ttacgttccg ggccactgta cctgcttttt tattctccac caccacattg
     4561 tactgtacct gttctccgac ctgccattca taatgatctg cagatttctc aatccagaat
     4621 tctcctgaat ttacatatac ttctgcatca tcagatctct catctgtatt agcagctttt
     4681 acagttgctg catttacgct ttcgtgtcca tttgcctctt cctgtgcgat acaatggaaa
     4741 ataatcgtta caggctgact gtatggcaca taagaacaat aaaaggaaaa tccgttctca
     4801 tctgcattca actgagaatc cacagatctc gcttcatatg cctgtcctgt tttcttatcc
     4861 ggtacgggat agtttacctg ttgctgaact cccagtactt ccatgctctg tgcaccacct
     4921 gccagaacca gtccctgcgg cagaccaata tcagtaatag ttacatcttt tgcaattgtt
     4981 cctgccgtta cattattcac cacgatccgg taagctacct gctctcctgc ctgccattca
     5041 tatttgtctg ctgttttatc aatttcaagc tgtggactgt tcggccatac ttctgccata
     5101 tcctttctgg attcctgttc tcctgtctca ggattgatca gattatccgc tgttgcagtc
     5161 acaatatttt cccattcctg tccattggaa tccgcagatg cctgacattt aaaacggatt
     5221 gtgatcgtct ccccatactt cagggacgga cactctgctt tccatccatt ttctccctgt
     5281 ccggtaagcg tacagttctc gcctccctga cttgtctcta cagcatactg cccttccaga
     5341 aactgcagac atgatggaag ctcgtctgta ataacaacat ttactgcttt tacatcctgt
     5401 tttgtctgag aaaccagaac ctcataatct atgatatctc ccgttttcca ttcatactga
     5461 gaagtatttt tctttacttc cagttccggt ggaatcacac cctttaccca cactgtttcc
     5521 gtatccattg tatctccgct tccgtttgta cgttcataac tcatggatgc atggtttggt
     5581 acaagaatac tgtatccatc ctctgcaagg tattttgaaa tgttaatttc tgattccggt
     5641 ctctggcgta cttttaaagt aaatgtgtaa gtctgattat ctgtaaatgc ttcatcctga
     5701 aggctctctg ctttggccct gcaggtcact ttctgtcctt caacagcaac atcaaaccag
     5761 tctgtcactg tctgccctgc atcattcaca atactgactt ttgatgcatc ctctatagta
     5821 agacaatcct caagtatatc ctgtaccaca aaggatttca gtctattggg tgtcacctcc
     5881 gcccggatca tatactggaa ttcctgtccc tgacgaatgc caaaaggttt ttcttttgat
     5941 gtggcagctg cctgttccca tgtacagttt gcctctccca cacgtttctc aggcgctttt
     6001 ttcatctcaa catcaccgaa acaataggat gtaaaatcaa aatatgcata tgctttgcag
     6061 tatttctgtc ctttaaagtt cggacaataa ctgttgcctg atggatccag atatttattt
     6121 cttgtaatct ctgcccatct ttcctgagaa ccggcttttg caatggcatc ttcacgactt
     6181 ttatcccatt tatccagtct gaactgatga cagaattcta ccgtaaaatt atctgtatta
     6241 taaaaaagat tcagccatcc tctcggatca tccggctcaa cggaaccaag gggtgagctt
     6301 acagaattcc catctaccgt cagataatca ttgtttttca gaacatatgc attatccaga
     6361 ctgctgtctg acggaatacg gactccctgt cccgcatcaa tatcacgtat ggttccatgg
     6421 ccactgatcg gcagtgtttc ttctgttcca tgcttcagaa actgaaactt aacctttgcg
     6481 tatcctacag aataaataaa tacaccgata ctgtttttgg aaaagccaac cattggataa
     6541 gcttcattat ctttccatgc aaacgtagct ccgcctttat tctgaacaat cgattctgca
     6601 gtgcgcagat cataacgggg ttctgcattc tctactccca caagaatgag tctgacatca
     6661 acaatatttc catttccatc ttttcctaca ttgttataac gcatccctgc gcttccggct
     6721 ttatagtccg ctcctacacg aacgcactct gtgtcacgtt cactttttcc attgtctgaa
     6781 aaagcttccc tgtccagatt atcacaccca aaagattcat atgtggtaat tccgggctga
     6841 aacttcatgt taaagcgata accataatct accaccttgt cactgtccca tgtttctaca
     6901 gttaacggtg ccgcctgagt tacgcagaca ggcacaagcc ccagaattgc ctgcagaata
     6961 aaaagcattg caagcagcaa agctccaagg cgttctttca gtttgaaatt gtgtttcatt
     7021 ttccgtctcc tttccgaaca aaaaatataa aaatgaatgt gggatttttc cctgcacctg
     7081 gcaggattaa agaatagaaa taagttgaga ttgtatgatt ataaatattc aaggggaatt
     7141 aatatcgtga aacaagaacg tttacactta agattttaag attctgcgca gggtttcttt
     7201 tctgaaaccc tgcacagatt ttcattgatc atttcttttc ttcagccatg aaagaaaata
     7261 aagaataatt gcaagaataa taaaaaacgg aatcgcaact ccgattatca gtatcagtaa
     7321 aacaattata acagccgccg ctgcaataac aacagccttg ccatgccagg tagaaagatc
     7381 gattactttt ttccatcttt tctcctgctg atgaggaagc tctgtctcat tgccataact
     7441 acttccgtaa gaagaatact ctccgtaatc ttcctgtgta cttccatcat ctgtatcgat
     7501 cagagttttt gctatcagat gcgggtctcc cagttcctgc agtacttcct gctctgaacg
     7561 tccgccacgt acctgagact gtatataatc ttcataatac ctgatatgtg ctgctgcttt
     7621 gccctcctgc atctgcccgg caagctggct tctcaggatt tccaaaaatt cttttctgtt
     7681 catcttctac actccatttt gccagaaata catatcaaaa ctctactgct ctctccgtta
     7741 tcagtaacgt tcgtactctt attttaccat atataccgca ggtagcaact aatataatca
     7801 taaacttttt atgaaattct tataaacaca tatatcgttt tggaaataac actgcaaatc
     7861 cactcggatt ctcctgcttt cgtcattttc cgacaatttt tgcatacatc tccggtctgc
     7921 ggtctctgaa aagtccccag ttcagtctgt ctgcctttaa tgcatccagg tcaaaagtgc
     7981 ttacaagcac cccctcttcc cctccgggca gttctgcaca gagagcacct gtgttgtctg
     8041 tgataaaaga agagccgtaa aaattaagag cagatttctg cattccgttt tccggacatg
     8101 gctctactgt ttcctcaccg attctgttgg cagcgatcac agggatcagg ttggaggcag
     8161 cgtgtccctg catacatctt ctccagtgtt ccatgctgtc gcattccagg atgggttcac
     8221 ttccgatggc agtgggataa aagagaagct ctgctccctg cagtgccata catcttgccg
     8281 tttccgggaa ccactgatcc cagcagattc caactccaat ggttccaaat ctggtatcaa
     8341 aaaccttaaa gccggtatct cccggtgtga aatagaattt ttcctgataa taatggtcat
     8401 ccggaatatg tgttttccga taaatgccga gattctttcc atctgcatcc agaaccgcaa
     8461 cgctgttata agtattattg acctcttttt cataaaagct gaccggaatc acaatcccca
     8521 actctgccgc taccctgctg aaatgacgca ctgcagggtt ttcctctgca gtctgcgcat
     8581 attcataata ctcatatctg cgctcctggc agaaataggg ccgttcaaaa agctccggca
     8641 gaagaacaat ctcagctccc tttgctgctg cctgacgcac cagttcctct gcatgggcaa
     8701 tatttttctc cacactttta ctgcatttca tctgaactgc tgccactgtt acatttctca
     8761 tcctgtctgt tcctcctgct cctgtttaca taagtaagtt ttttcataac tttcaggtaa
     8821 taaccctcaa acacatgact ctcaaagttt tctgcatcaa ggtcagatat tttttccggg
     8881 aatctgctgg gtgatacagt gaatatttcc accgccaaca atgatggctc tggcatcaat
     8941 gggataaatc cttctttcag gaaaacactt ctgcagaatc tccactgccc ttttgtcatt
     9001 ttcatcccca aattgtggaa ggatgatccc tccattggaa atatagaaat tcacgtaact
     9061 ggcagccatc cgttctcctg cttcccgttc gtcttctccc tcttcaaaca caaagccatc
     9121 cacatcttcc tgggtaaggc agaccggttt ctgaggaatc ggaagcttat gaatcttaaa
     9181 ttttctgccc tttgcatctg tttcctgttc cagcaccttc agatcagcca aagacatggc
     9241 atactgcgga tctgtctcat cctctgtcca tgcaagcaca acctctccgg gccttacaaa
     9301 agcgcacacg ttatccacat gctcattggt ttcatcctga tagattccac atggaagcca
     9361 gataatcttg tggacaccga gccagtactt caactgttcc tctatctgtt ccctgctcat
     9421 ctgaggattg cgtccctgac tcagaagaca ggcctctgta acaatcagag tcccctctcc
     9481 gtcagaatgg atggaaccgc cctccagcac aaaaggtctg gcatccagac atggacaacc
     9541 gagagtcctg cagataaagg cagccaccct gtcatccttt tcccagttcc ggtaaagccc
     9601 gtcaaaggta cctccccagg cattaaactg ccagtcaact ccacagaccg cccctttctc
     9661 atccagaacc atggttgctc ccacatctct ggcccaggcg tcatctgtct cgcattccag
     9721 caaagtcaca ccggaaacat tcccaagctg attctttgca ttctccatct gagctttgga
     9781 aaccagcata tacacctttt cgctcactcc aatagcctct gcaactttca caaatgcttt
     9841 ctgtgcttcc cttgccccat aattccagga accgggacgt tccggccaga tcatcacaca
     9901 tccctcatga ggctcaaatt ctccgggcat acgatatttt gttctgttct tctctgtaac
     9961 ttccatgtct gtctcctttt ctttgatagc ccggcagata tcaggaaagc cggctcttaa
    10021 agtcttcgta tccgaaatgt ctgataacct cacactctcc gtcctcatgc ataaccgcaa
    10081 tatccggcag cggcataccg ttaaatgtat tattcttcac catagaataa atcgccatat
    10141 ccataaaata cagcttgtcc ccgatctgga tctctctgtc aaaggaataa tctccgatca
    10201 catctcctgc caggcaggtg caggaagata agcggtaggt atatgccttc tcccctgctt
    10261 ccccgctgtc cttaagaggc ggacgatagg gcatctccag cacatccggc atatggcagg
    10321 ctgcagaagc atccaaaatc agcgttctga tctcattttc cacaatgtcc ataacctctg
    10381 tcaccagata tccggcattc agggcaacag cctccccggg ctccagataa atatccagat
    10441 cataggtttc cttcatatgc tgaatacatt tttccaggag ctttacatta taatcctctc
    10501 tggtaatatg atgtccgcca cccatattca gccaggaaac ctcagacaga aattctccaa
    10561 acttctcctc taccgcctgc aatgttttct ccaggtcatc cgcattctgt tcgcagagcg
    10621 tatgaaaatg cagtccgtcg atccatttca gacattcccc gtcaaagttc tctctggtaa
    10681 cccccagcct tgaacccggc gcacagggat catagatcgc atgatccccc tgagtggagc
    10741 attccggatt aatacggagt cccagactgg ctccggtaca cacttcttta aatttcttca
    10801 gctgtgctgt ggaattaaag ataatatggt cacagatccg atccagttcc tctatatctt
    10861 ctgtacggta agcaggggaa aaaacatgat tctctttccc catctcttca tatccaagcc
    10921 ttgcctcaaa cagaccgctg gcagtggtac ctgccagata ttttccgatc atgggataca
    10981 gagcaaaacc ggaaaacgct ttctgcgcca gaaggatctt acacccggta tcctcctgga
    11041 cttttttcaa aatctccaga ttctcccgca tcttcttctc atcgatcaca tagcagggag
    11101 tttgcagttg attaatcttc attggctttc cagaccttta ccagttcagg atcttcgcag
    11161 actttccatg gaagtcccca tttgttcagt gcttccatat atggatccgg atcaaattct
    11221 tccacattaa atacacccgg cttcttccac tgtccggtca ctaccatcat ggaaccgatc
    11281 atagccggaa cacctgttgt ataggagatt gcctgggatt ccacctcttt atagcattcc
    11341 tgatgatcac atacattata aatataaata cttttctctt ttccgtcctt aacacctgtg
    11401 aaaatacagc cgatatttgt tttacccact gttctcggac ccaaagatgc aggatccggc
    11461 agaagagctt tcaaaaactg gatcggcacg atctcctgtc cattaaattc cacaggtgcg
    11521 gtggaaagca ttcctacatt ttccagacat ttcatatgtg tcagatagct ctgtccgaat
    11581 gtcataaaga aacggatcct ctgtactccc ggaatatttt ttgccagtga ttcaatctct
    11641 tcatgatgaa gaagatacat atccttcttt cctacctcag ggaaatcata gacagattta
    11701 aattccatag gctctgtttc tacccaatgt ccgtcttccc agtaggaacc atttgcggaa
    11761 acctctcgaa gattgatctc cgggttaaag tttgtggcaa aaggatatcc atgatcaccg
    11821 ccgttacagt ccagaatatc aatggtatgg atttcatcaa aataatgctt caaggcatag
    11881 gcactgaata cactggtaac acccggatca aaaccggttc ccagaagagc agtcagtcct
    11941 gcttccttaa atttctcatt ataagcccac tgccaggaat aatcgaaata tgcagtaaag
    12001 cctttttctt tacatctctt ttcgtagatt gcacgccatg tgggatcttc tgtatcctct
    12061 gcttcataat tggcagtatc aatataatcc gcaccggctt ccagacatgc atccatgatg
    12121 gtaagatcct gatatggaag tgccacattc aggacagcat ccggcttata ggctctgatc
    12181 aattctgcga cctctgctgc attatccgca tctacctttg ctgtctcaat ttttgtcttc
    12241 gttgtacttt caatcttctt tttgagtgca tcgcattttt cctttgtcct gcttgcgatc
    12301 ataatctctg taaaaacatc gctgttctga cagcatttgc gaattgccac tgaagctacc
    12361 ccaccacatc cgattaccaa taatctactc ataaactgtt ttcctcctct tccagtaaat
    12421 cttctacata ttttggaagc ataaatgctc ctctgtgaag gtttgttgta taataccatg
    12481 tttctatatt aagattatca aacctctccg gcctgaaatc ttccagtgga tgatatttct
    12541 ttgatgcaaa tccaaaaagc cagtatcccg agggacaggt agggatatgt gcctgataaa
    12601 ccctgctcac cggaaatgac cggaaaacct ttctgtgcat ctttctgcat tccacctcat
    12661 cctcatcata aaaaggactt ccatgctgat aaaccatgat tccgtcatct ctgagagcct
    12721 tataacagct tccgtagaat tcctttgtaa aaagtccctc tgtatgtccc agcggatctg
    12781 tggaatcatt gatgatcagg tcatatctgg cctttttatt ccgcaggaac cgaaggccgt
    12841 cttcataata aatgttgact ctctcatcct tcagtccctg ggcaatatcc ggaaacatct
    12901 ccgcacatac atccacaaac attttatcgg attccaccac atcaatgctc tcaatctgtg
    12961 gataatggat cagttctctg gcaactccac cgtcaccgcc accgataatc agaacatttt
    13021 ttacattggg atgtactgtc attggcacat gcgtgaccat ttcatcataa ataaattcat
    13081 ccttgtcaga aaatacgatc tcaccgtcca gagccacaaa tcttccaaat tcttcagact
    13141 caaacacatc gattctctga aattcacttt cccctgaaaa taactgtcgg ttaatccgga
    13201 cagaaagctt tacatttcct gtatggaact cggaatacca taattccatg atcagatacc
    13261 ccctttcaga acctgaagat attctacctt cggatcctcc attccctgca tggaacagcc
    13321 tttgtctctt gcataaagaa tgtattctac aatttcctgt gtcaccattt ccccaggagc
    13381 aagaatcggg attcccggag gataacacat aacaaattca ccgctgatcc tgcctgccgt
    13441 ctgttccatg ggcagagatt ctttctccgc ataaaatgcc tgctgtggag acgccaccac
    13501 tgcaggtgcg atatattccc cggaaagcat acctgtgctg tccttcttat acagacgttc
    13561 aatatcagcc aatgccccta ccagtctctc aatatcctga agcctgtctc caatggaaat
    13621 gtaagccaga atattacaga tatctccaaa ctcgatctga atatcatatt catctctgag
    13681 aagatcataa acttcaatac ctgccagccc atttcccagt gtataaatgg agagttttgt
    13741 aacatcaaaa tcaaaaacac tggttccatt gatcagatcc ataccatatg cataataacc
    13801 gccgatctca ttgatctcct ctctggcata ctgcgccatc cctgcaacct tttcaaagga
    13861 ttcctctccc ctgagtgcca gatttcttct ggagatatcc agactggaca acagaagata
    13921 agaagcgctt gtggtctgag tcagattgat gatctggcgc actttctctg cattcatact
    13981 cttattcaaa agcagcagcg aactctgtgt cagacttccg ccggatttgt gcatggaaac
    14041 tgccgccatg tcagcacctg ccgccattcc ggatacagga aggtttctgc cgaaataaag
    14101 atgggttcca tgagcctcat ctgccagcac cttcattcct cttgcatgag ccttctttac
    14161 gatagtccgc agatccgaac agattccata ataggtaggg ttatttacaa gaactgccac
    14221 cgcatccgga ttctcatcca tagccttctc cacctgactg acttccatgc caagggaaat
    14281 gcccagctgc gcattcacct ccgggtttac ataaaccgga attgcaccgc acagtaccag
    14341 ggcattgatg gcacttttat gtacatttcg cggcagaatg atcttatccc ctgccttgca
    14401 gacagacagg atcatgctct gcactgcaga tgtggttcct cctaccataa ggaatgcatg
    14461 cgctgcgcca aaagcatctg ctgcaagctc ctccgcttct ctgatcaccg aaaccgggtg
    14521 gcagagattg tccagcggct tcatagaatt aacatccagc cccacacatt tctctcccag
    14581 caactgtgca agctccggat ttcctcttcc tcttttatgt cccggcacat caaagggaac
    14641 gactctcttc tttcggaaac gttccagtgc ttcatatatg ggcgcatgct gttgtctttc
    14701 ataatccatt tgacatgttc ctcttttcct gtcgtcatgt accggcaaat acagttctat
    14761 cattcagcaa ttgtatactg cctcaaaccg gcacaatgat tcaattattt ctctatatat
    14821 tcaagtcgaa cgcatgtgag acacatcctc gcaaagcgtt tatctccaac catatccttt
    14881 atatttgcta tatctgcaca aaaaaagaag cagataagtt cattcaccat ctgcttctct
    14941 catgatctat agaatttctc aggctctgtc tctttatata ctgaccggat ttcccgtata
    15001 aatccgtctg tatcctgtgc ctgttcccgt attctgaaat attcatgact gctgtcgtct
    15061 tcaatcgctg gcaaatatat gctatgctct tattgaccgt ttcacaagat gatgtgtgct
    15121 tacgcactga ttattataaa gtaatcaact tataaaattt gagcttctaa ctcaatcaat
    15181 aatgtggtgt ctcccacccg gcaactgccc cgcctgtccg tatggcttaa cattcagaaa
    15241 ctgtctctga atgtgagcaa atatttgcat gaaaacgata gtgtcttttc atactaaaga
    15301 tgagaataac atatcttctg aactgttgtc aattccattt tccatatttt gcacagtctt
    15361 tacccgcttt ttatattttc ttcatttatc agggaaaact atgtctattt tttaacaatt
    15421 tctttccttg agaaaacgta ttttctttca ttaccaggga ttacgattct cttctcttat
    15481 caatttgcac aacttttatc cagtttactc acattttttg acgtttcaac aaaaattttc
    15541 ttgacatttt tttctcaaaa tgatatattg tattcatcaa ttgaaagaac cttcgagtac
    15601 tgacggaaag agtggagtgc aaaccacgtg gagtcggagg tttgtgggag ccgaccgtct
    15661 gggcagtatt tgaaatattc agatactggc ctttttttat aactttcagg gcagaaatca
    15721 ggaataccag gcagaccggc caatacttct ttcaattaat aattgttgct gatcgcggag
    15781 tgaacagcaa cagaagtttt tcatgttatg cggaaacgaa aggagaaaaa caattatggg
    15841 attcaaatca gacattgaaa ttgcacagga atgcgagatg cttccaatta ctcagatcgc
    15901 agagaaagca ggtattgacg acaaatatct ggagcagtac ggaaaataca aagcaaaaat
    15961 cgactacaat cttctgaaag aaagtgataa gaaggatgga aaattaatcc tcgttacagc
    16021 tatcaaccca actccagcag gagaaggtaa aactactact actgtaggtc ttgcagatgg
    16081 tatgcagaga cttggcaaga gtgttatggt agctcttcgt gagccatcct taggaccggt
    16141 attcggtgta aaaggtggtg cagcaggcgg cggatatgca caggttgttc ctatggaaga
    16201 tattaacctt cacttcacag gtgacttcca tgccattggc gcagctaaca acttactggc
    16261 agctatgatc gataaccata tcttccaggg caatgcatta aacatcgacc cacgtaagat
    16321 cacatggaga agatgtgtag atatgaacga ccgtcagctt cgtaacgtag tagatggtct
    16381 tggcggaaag acaaacggta tgcctcgtga agacggatac gacatcacag ttgcatctga
    16441 aatcatggca gttctctgtc ttgcaagcga catcaaagac ctgaaagaaa gattatccaa
    16501 gatcatcatc ggatatacat acggaaaagt ttccgagcag aaacctgtaa cagcaggtga
    16561 ccttcacgca gaaggcgcta tgacagccct gttaaaagat gctctgaaac caaaccttgt
    16621 acagactctg gaacacgttc ctgcaatcgt acatggcgga ccattcgcaa acatcgctca
    16681 tggatgtaac tctgtaacag ctacaaagat ggctatgaag cttgctgatt atgcaatcac
    16741 agaagctggt ttcggtgctg accttggtgc tgagaaattc cttgatatca aatgccgtat
    16801 ggctggttta aaaccaagcg cagttgtaat cgtagctaca gtacgtgccc tgaaatacaa
    16861 cggcggcgtt gctaaagctg accttaacaa tgaaaacctg gaagctcttg aaaaaggtat
    16921 cccgaacctg ttaaaacacg tttccaacat caaaaacgta tacaaacttc catgtgttgt
    16981 tgctatcaac gcattcccta cagatacaaa agcagagctt gactttgtag aagctaaatg
    17041 taaagaactg ggcgttaacg ttgctctttc tgaagtatgg gcaaaaggcg gcgaaggcgg
    17101 aatcaaactt gcagaagaag ttatccgtct tgttgaagaa ccaaacgact tctcctatgc
    17161 atatgaactg gaaggttcta tcgaagacaa actgaaccag atcgttcaga aagtatatgg
    17221 cggtaagaaa gtagttctga cagctaacgc tcagaaacag gcgaaacagt tagaagctct
    17281 tggctttggc aactgcccga tctgtgtagc taagacacag tacagcttaa cagatgacca
    17341 gactaaactg ggtgctccta ctgacttcga agttacagta cgtaacctga agatttccgc
    17401 tggtgcagga ttcatcgtag ctcttacagg cgagatcatg acaatgccag gtcttcctaa
    17461 agttccggct gctgagagaa tcgacgtaga cgagacaggt aagatcacag gtctgttcta
    17521 atccggttga aatcaatcga ataattcaaa aatataaaaa tcatatttat atatgatatg
    17581 tgtccagacg attttacagg cgggaagatt ttcccgcctg tttttttctt tattttttta
    17641 taagataatc ttttccggaa ataccaggtt ccgtcatatg gatcggatcc agaatgcgat
    17701 taagttcatc ctcgtccata agcttttctt tcagaatcag acttcttaca gattcgcctg
    17761 tcttaattgc cttttttgca atatccgcag ccttctgata tccaagatgg gggctgattg
    17821 cagtgataat acctacactg ttttctacca gataacggca tctttcttca tttgccgtaa
    17881 ttcctacaat acaattatct accaatgtct ggactgcata gccaagagta tcgatagact
    17941 gaaacatgca atagaaaata atcggctcaa acgcatttaa ttccagctga ccagcctctg
    18001 cagccatggt aatggtaaca tcattaccaa taatattaaa agcaacctga ttcactactt
    18061 caggaataac cggattaact ttacctggca taatagagga accattctgt tttgccggaa
    18121 gattaatctc cccaaaacca gtacgtggac cggaggacat cagacggaga tcatttgaca
    18181 ttttggaaag agttaccgca catgctttca cagcaccgga aacagctaca aatggatcca
    18241 gattctgagt ggaatcaatc agatcaaaag cctgtataaa gtccattccc gatatttcag
    18301 tgagatttgg aacaattctt ctcagatagc cctcatctgc attaattcct gttccaatag
    18361 cagtacctcc catattaaga gtccgcattt catccattgc tttatccatt ctgtggatat
    18421 cacgcatgat tgctaccgaa tatgccttaa attcctgtcc cagacgaatt ggtactgcat
    18481 cctgcatctg tgtacgcccc atttttatta tgtgatcaaa ctctgtagct ttttcattaa
    18541 gagcatcata gaggcgaaga agctgttttt tcagattctg caacaaacga agagaagtca
    18601 ttttaccggc agtaggaatc acgtcattgg tagactgtcc acaattcaca tcatcgttag
    18661 gatttataat tgtataatcg cccttttttc ctcccagtat ctcaatcgcg cgatttgcaa
    18721 ttacttcatt ggcattcata tttaaagatg tgccagctcc tccctgaaca ggatccacaa
    18781 taaattcatt atggaatttt cctgaaacaa tttcatcaca tgcctggaca atcgcctgtg
    18841 cttttttctt ctcaagaagc cccacctcac aattggttat cgctgctgct ttttttatgt
    18901 atgcaagact gttaataatt tccggatgca tattcaaccc cgtaatgtgg aaattttcag
    18961 ccgcacgtaa agattgtact ccataatata catcttccgg aatatccttt acaccaatag
    19021 aatccctttc tacacgatag tctgtttttt tcatagttat tcgccctccc atgtatttgc
    19081 cctcattata tatctctgct ataatataat caaatacata tatttttata aaatatatag
    19141 tgtttaaatt atatatcgga ggagtttata tgtttcaggg aatggaatac atctatgagg
    19201 tctacaagga aaaaagcttt tccaaagctg ctgctgctct tttcatttcg cagccttctt
    19261 taagcgccaa tgtaaaacgt gtggaaaacc gtattggcta tcctattttt gatcgaagta
    19321 ccaaaccttt acagttaact gaagtcggaa aacattatat acaggctgtt gaaaaagtca
    19381 tggatattga aaataatctc gaaaactacc tactggatct gggaaatctc aaaacaggaa
    19441 ctcttaatgt aggtggcagt aacttttttt cttcgtggat tctgcctccc cttattgctg
    19501 atttttccca aaaattcccc catgttcaaa tttctcttgt agaagaaagt acagcaaagc
    19561 tatcccagtt tctccaggcc ggaaagttag atctggtgat tgataactgt attctggata
    19621 accagatttt tgaacgttat atctaccaga aagaacaact tcttcttgca gttcccaaaa
    19681 attattcagt aaataccaga ctgcagaaat atcagattcc tattgaggaa atccggaacg
    19741 ggcagttccg ttcttctcat attccttctg ttccattaaa caaattcgag aacgaaccat
    19801 ttattattct tcgttcagat aatgataccg gtaagcgtgc acttaccatt tgtcaggaaa
    19861 atcacttttc gccttctgta gtatttcgcc tggatcagca gatgactgcc tataatattg
    19921 catgtttggg aatgggtatc actttcatcg gggatcttct gctctccaga gttccaacaa
    19981 attcagaact tgttttttat aagctgcccg gtcagagcag taaacgcact gtgttttttt
    20041 actggaagaa aggccgctat atcagcagag ccatggaaga attcctgaag ctgccctttt
    20101 cctgatatgt cataatcaaa taggttatgg tgattggtca tcatcagatg tacgtcaaaa
    20161 tggggttgtt gtgctaaata agcacaacaa ccccagtatg tcaggcagat attcgattag
    20221 aacagtggct tcatagccgg atacagagtt ctgaacttct gatatctctc ttcatatttt
    20281 gcaaccagtt caggatccgg ttctactgta tcaacaactt tggcaaattt cttaccgatg
    20341 gtttccacat ccgggtaagc accacagcct actgctgcca gcatagctcc acccatggac
    20401 ggtccttctt cgttctccag aacatcaacc ttcaggttca taacgtttgc aatgatcttc
    20461 ttccacagtg ggctcttagc tccaccaccg cagatcttgg ttctctcaat cttgattcca
    20521 aggtttcttg caacttccag ggaatcacga agaccaaagg caacaccttc cagaacagcc
    20581 tgtgtcatgt ctgctcttgt gctgtccatg gacattccga agaatacacc tcttgcatca
    20641 ggattattat gaggtgaacg ttctcccatc aaatatggaa ggaagaatac atgattctct
    20701 cccagcttct gaattggagc ctgctctgct gcgaaatcct ttgtctgaag aatctcctct
    20761 gcccaccatt tgttacagga agctgcgctg agcatgcatc ccatcagatg atagcttcca
    20821 tctgcatgac agaaagaatg aagtgcgtta ttttcgtcca caccaaagtt tttactggaa
    20881 ataaacacag ttccggatgt tccaagagaa atattacact gaccgtcacc aactgtacct
    20941 gttcctacag cagctgccgc attgtcacct gcacctgcaa caacttttac attctcactg
    21001 aatccaagtt ctttcgcaat ctcaggtttc agagttccta ctacttccca actctcatac
    21061 agtttcggaa gctgctcttc tgtgattcca cagatctcca gcatttcttt tgaccagcag
    21121 cggttcttca catcaagaag aagcataccg gaagcatcag aaacatctgt acaaaaagaa
    21181 ccggacagac gatatgccag ataatcctta ggaagcataa tctttactac cttcttaaag
    21241 ttctcaggct catttttctg catccagagg atcttcggtg ctgtgaagcc tgcgaaagca
    21301 atatttgctg tatactgtga aagtttgtct tttccgatca ctgtattcag atattctgtc
    21361 tcttcgcctg tacgtccgtc attccagagg attgcaggac ggatcacatt atcatccttg
    21421 tcaagtgtta ccagaccatg catctggccg ccaaaaccaa ttcctgctac ctgcgctctg
    21481 tcgatatcct ttgtcagctc tttcatgcct tccatactct gcgcaaacca gtcttccggt
    21541 ttctgctcag accagcccgg atgtgggaag aataaaggat attctctgga tacgatgtta
    21601 cagatttttc ctgattcttc cataagaaga agttttacag cggaagtacc aagatcaata
    21661 ccgatataat acataagtgc gctccttttc tatttctaat ctaatacatc ccagagcaaa
    21721 gccccgggat gcctttaata tagtgtcagt ttatttattc tgtattcaga ttcattcact
    21781 tcacatgaac attaataacc cgttttactg atttctcatt aaccccatgg attctctgtc
    21841 ggatatctta cacctgccgg ctggttgtat ccaatcttct taacatccag tccaaggaat
    21901 ttcactacct catagaatgc ttttccgtaa tgtccaaaca taactgctcc atgatgcgga
    21961 tagttgccct cgatcagtac gtgacggtag aatcttccca tttctttgat tgcgaaaata
    22021 ccgataccac cgaatgatct tgtaggtaca tccagtactt caccttctgc aacataagaa
    22081 accagctcgc cctcggaatt gcactgtaaa cgatagaatg taatgtcaga tgcagcaata
    22141 tcaccttcaa gagttcctct tgtaaagtct ggttcagatc ctgccggctc aagaagtctg
    22201 tgctggatca gctgatattt aacagctctg gaatcacaca tcttgcatgc aggagtattt
    22261 ccacaatgga atcccataaa tgtatcagta agcttgtaat cgtattttcc tttgatatct
    22321 tcatcataga tatactgtgg aacagagttg ttgatatcaa gcagtgtaac tgcatcattg
    22381 gaaatgcaaa gtccgatgta ctcactaagt gctccgtaga tatcaacctc acaggatacc
    22441 gggattcctc tggaaaccag acggctgttt acatagcaag gttcaaatcc aaactgtgac
    22501 gggaatgctg gccagcattt gtcagcaaat gcaacatatt ttcttgctcc cttatgagcc
    22561 tctgcccagt caagaagtgt aagctcaaac tgtgccattt tcacattaag gtcagcataa
    22621 tatttgcctt cgcccatctc ttttgccata tctgcacaaa cttccgggat acgaggatca
    22681 ttttcatgct ctttgaaaga aacaagaaga tcaagctctg agttctcttc aatctcaaca
    22741 cccagctcat agaggccttt aataggtgcg ttgcatgcga agaagtcctg tggacgtggt
    22801 ccgaaagtaa tgatcttaag attgctgaca ccgatgactg cacgtgcaac cggtacgaaa
    22861 tcagcgatca tctttgcaat atcatctgct gttccaacag gatattccgg aatatatgct
    22921 ttcagatgac gcatttttaa gttgtaggag cagttaagca taccacagta agcatcacct
    22981 ctgccgttga tcatatcacc gtcaccttct gctgctgcta catacataca aggtccgtca
    23041 aatctctctg cgatcagagt ttcaggagtt tcaggtccga agtttccaag gaaaacaacc
    23101 agcgcattac actctgcttt gtttacatct tcaagagctt tctccatatc cttctcgttc
    23161 tcaacagtta caggacattc ataaagttca cctttataag tttccttaat tgctgcacgt
    23221 ctcttttcag aaagctgaat cggaaaaca
//
