LOCUS       gnlProkkaPBIKMNCH_127   4290 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PBIKMNCH_127.
ACCESSION   gnlProkkaPBIKMNCH_127
VERSION     gnlProkkaPBIKMNCH_127
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 09:42:16
            Original ID  :: gnl|Prokka|PBIKMNCH_127
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4290
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4290
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1261:4243]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1262..4243
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..4290
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4290
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             2..109
                     /locus_tag="ctg127_1"
                     /transl_table=11
                     /translation="MVEDILKQLPTFFILKTQYDVQTVYDKITLQSKYG"
     CDS             complement(145..1248)
                     /locus_tag="ctg127_2"
                     /transl_table=11
                     /translation="MQNERFTIEETRQMVEKMEDVVLDSIIYTVQQRGVLNDAATIYNF
                     KEILDRLNCQQQYCHIINRWIKALVQRGRIKPASGDGYYGTSHVTEELVEQKWDEARKM
                     WDYRFGSPLVMEYWYMNFRNLLDLIKGKTQAVFLLFPQGEDKYAKALYSDTKIAQYINL
                     KMVDIIEGHFRAFCKESTDKLKILEIGGGTAATTEMVLKALEVNSDITKIEYNFSDISK
                     FFLIRAKKIFEKYDFVKYRILDVDCVKKGLLFDKEKFDIVIAAGVLNNAYSIEATLAAL
                     YDILEEGGLFIFSEPIQESLEILISQAFMITKPKDIRMDCEETFMTKEQWEKVISNSGF
                     MIKTIYPQEDEPMAVFGQRVFAVIKEN"
     CDS             complement(1262..4243)
                     /NRPS_PKS="Domain: cMT (326-473). E-value: 3.4e-30. Score:
                     96.1. Matches aSDomain: nrpspksdomains_ctg127_3_cMT.1"
                     /NRPS_PKS="Domain: PP-binding (610-681). E-value: 1.8e-07.
                     Score: 23.5. Matches aSDomain:
                     nrpspksdomains_ctg127_3_PP-binding.1"
                     /NRPS_PKS="Domain: Thioesterase (714-986). E-value:
                     1.5e-12. Score: 40.3. Matches aSDomain:
                     nrpspksdomains_ctg127_3_Thioesterase.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 90.7;
                     E-value: 1.2e-27)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg127_3"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-34, bitscore:
                     107.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.8e-09, bitscore:
                     23.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLVAFRKRLSNYYLCEEIDDSLGSVPYGKPLSNQYFKILDKKMR
                     MCPLYVSGELYIGGQSLADCYYNDTYTTSSHFIDYTENERLYKTGDYGYYKESGDIIFQ
                     GRRDEQVKLRGYRIELGEVEAALQKNPLVKQAAVVINKAGAEATLNAFIKLQDDAESIN
                     TFQLSNITQTQIKELYNDIFAEYEAEKIALANSILEEYVLYSILEYLKENHLTQNKKID
                     FSLMKQKESIKSEYHWLIKRWLDKLCECGKLVSTNEDVYELKSDNINEKVKIYRESLYS
                     TWNNEIMPETFILYIEENLKQISGLLSGKVNPVDILYPYGEWKIVRDLYINSKVSHYIN
                     SCIEELIQNMLSYNNERTIRILEIGAGTGAVLEKISGILEKSNIEYYFSDVSSFFITTA
                     KAKYQHPNIKFGIYNIDEDYRKQGLLPNMFDMIIAVEVVENAKNIPYTMQMLKELIAPK
                     GWLVLSESVIEPAWILASQAFLMQEPQDDLRKNTSYLGQSDWIKLLMEIGEGDMYSWPE
                     QGSSIDSFGIRLFAKQVKKQMPHYDLDEIKDGLKKELAGYMIPSNMQVIDSLPLTANRK
                     IDRRVLERWSDIGQFGSNSQQEEIISDERSEEQKKIEKIFKDSLGVDAIEWNRSFYEYG
                     ADSLIIAQIAGKIMQFLNEEQGMDIPYDVILRQLLNQSTLEKFEEFVDTYGTKNADDGD
                     DKKNNYEVIRYIESEEETACVLFHGGLGTLDNYRNLVKYLQCGEQIEVIGFAIKDSFKY
                     CKISPENLYQAISLEYAAYIQKRGIKKVQLVGHCIGGRIAVEVARILSEKGIKIVDVVL
                     IDSVPLMSNVPDDSYLELMFPAFLNISFKDMGLTDLSTTEIMNEMILLLEGDDKADNRL
                     KKLLDKLKTLDETKKISMYADTLLRLYGKRIPNDMVKSMLNAFIHSSKGAKYEPEPYIG
                     DIRLLLAKEQYFPVRNLTEKAIQFWKDICIGNLQTMTILGNHFTCIEDEKNAAMVANLI
                     LKHI"
     aSDomain        complement(1286..2101)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg127_3_Thioesterase.1"
                     /evalue="1.50E-12"
                     /label="ctg127_3_Thioesterase.1"
                     /locus_tag="ctg127_3"
                     /protein_end="986"
                     /protein_start="714"
                     /score="40.3"
                     /tool="antismash"
                     /translation="VLFHGGLGTLDNYRNLVKYLQCGEQIEVIGFAIKDSFKYCKISPE
                     NLYQAISLEYAAYIQKRGIKKVQLVGHCIGGRIAVEVARILSEKGIKIVDVVLIDSVPL
                     MSNVPDDSYLELMFPAFLNISFKDMGLTDLSTTEIMNEMILLLEGDDKADNRLKKLLDK
                     LKTLDETKKISMYADTLLRLYGKRIPNDMVKSMLNAFIHSSKGAKYEPEPYIGDIRLLL
                     AKEQYFPVRNLTEKAIQFWKDICIGNLQTMTILGNHFTCIEDEKNAAMVA"
     aSModule        complement(1286..3265)
                     /domains="nrpspksdomains_ctg127_3_cMT.1"
                     /domains="nrpspksdomains_ctg127_3_PP-binding.1"
                     /domains="nrpspksdomains_ctg127_3_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="ctg127_3"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       complement(1844..1900)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg127_3_0003"
                     /evalue="2.80E-05"
                     /label="NRPS-te1"
                     /locus_tag="ctg127_3"
                     /protein_end="800"
                     /protein_start="781"
                     /score="16.7"
                     /tool="antismash"
                     /translation="QLVGHCIGGRIAVEVARIL"
     aSDomain        complement(2201..2413)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg127_3_PP-binding.1"
                     /evalue="1.80E-07"
                     /label="ctg127_3_PP-binding.1"
                     /locus_tag="ctg127_3"
                     /protein_end="681"
                     /protein_start="610"
                     /score="23.5"
                     /tool="antismash"
                     /translation="KIEKIFKDSLGVDAIEWNRSFYEYGADSLIIAQIAGKIMQFLNEE
                     QGMDIPYDVILRQLLNQSTLEKFEEF"
     aSDomain        complement(2825..3265)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg127_3_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="3.40E-30"
                     /label="ctg127_3_cMT.1"
                     /locus_tag="ctg127_3"
                     /protein_end="473"
                     /protein_start="326"
                     /score="96.1"
                     /tool="antismash"
                     /translation="RDLYINSKVSHYINSCIEELIQNMLSYNNERTIRILEIGAGTGAV
                     LEKISGILEKSNIEYYFSDVSSFFITTAKAKYQHPNIKFGIYNIDEDYRKQGLLPNMFD
                     MIIAVEVVENAKNIPYTMQMLKELIAPKGWLVLSESVIEPAWI"
     CDS_motif       complement(3872..3937)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg127_3_0002"
                     /evalue="9.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg127_3"
                     /protein_end="124"
                     /protein_start="102"
                     /score="33.7"
                     /tool="antismash"
                     /translation="FQGRRDEQVKLRGYRIELGEVE"
     CDS_motif       complement(4019..4102)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg127_3_0001"
                     /evalue="3.20E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg127_3"
                     /protein_end="75"
                     /protein_start="47"
                     /score="22.7"
                     /tool="antismash"
                     /translation="PLYVSGELYIGGQSLADCYYNDTYTTSS"
ORIGIN
        1 tttagttgag gatattttaa agcaacttcc aacatttttt attctgaaaa ctcaatacga
       61 tgtccaaacc gtttatgata aaataacctt gcaatcaaaa tatggataat aactaaaaaa
      121 gacagaaaat atagtaccca catattaatt ctcctttatg accgcaaaaa cacgttgtcc
      181 aaaaactgcc attggctcat cttcctgtgg ataaattgtt ttaatcataa aacccgaatt
      241 agaaatcact ttttcccatt gctctttagt cataaaagtt tcttcacaat ccattctaat
      301 gtcttttggc tttgttatca taaacgcttg ggatattaaa atctctaaag actcttgaat
      361 tggttccgaa aagataaaca gacctccttc ttctaaaata tcatagagag cagccagtgt
      421 cgcttcgata ctatacgcat tatttagtac tcccgccgca atgacaatat caaacttctc
      481 tttatcaaaa agcaatcctt tttttacaca atcaacatct aatattctat actttacaaa
      541 atcgtatttt tcaaaaattt tttttgctct tattaaaaag aattttgata tgtcagaaaa
      601 attatattct atcttggtaa tatcgctatt tacctcaagt gcttttagaa ccatttctgt
      661 tgttgccgcc gtacctcctc caatttctaa aatttttagt ttatcagtag attctttgca
      721 aaatgcccta aaatgccctt cgataatatc aaccatcttt aaattaatat actgcgcaat
      781 tttagtatca ctatataaag cttttgcgta tttatcttct ccttgtggaa aaagcaaaaa
      841 aaccgcttgt gttttgcctt ttattagatc taaaaggtta cgaaaattca tataccaata
      901 ttccataacc aacggagaac caaatctata atcccacatt ttccttgctt catcccattt
      961 ttgttctact aactcttcag tcacatgact tgttccatag tatccgtccc cagaggcagg
     1021 tttaatcctg cccctttgaa ctaacgcctt tatccagcga ttgataatat gacaatactg
     1081 ctgctggcaa tttaatctat ccaatatctc tttaaaatta tatattgtag cagcatcatt
     1141 aagcactcct ctctgctgga cagtatatat tatagaatct aataccacat cctccatttt
     1201 ttcaaccatt tgccttgtct cttcaattgt aaatctttca ttttgcattt cttttctcct
     1261 gttatatatg ttttaatata agattagcga ccatagctgc atttttttca tcttcgatac
     1321 aagtaaaatg atttcccaat atagtcatag tttgaagatt cccaatacat atatctttcc
     1381 aaaactgtat tgctttctcc gtcaaatttc tgacaggaaa atactgttct ttagcaagca
     1441 gcaaacgaat gtcaccaata tacggctcag gctcgtattt agcacctttt gaactatgta
     1501 taaatgcatt caacatactt tttaccatat cattaggtat tctcttgcca tataatcgta
     1561 acaaagtatc cgcatacata cttatttttt tagtttcatc taatgttttt aatttatcta
     1621 gtaacttctt taatctatta tccgctttat catctccctc taataaaagt atcatttcat
     1681 tcataatttc agttgttgaa aggtctgtaa gtcccatatc tttaaaacta atattaagaa
     1741 aggccggaaa cattaactcc aaatacgaat catctggcac attggacatc agcggtacgc
     1801 tatcaattaa aaccacatct acaatcttaa tccccttttc acttaatata cgtgcaacct
     1861 caactgcaat ccttccgcca atacaatgac caaccaattg taccttcttt attcctcgct
     1921 tttgaatata agctgcatac tctaatgaaa ttgcttgata aagattttcc ggggagattt
     1981 tacagtattt aaaggaatcc tttattgcaa aaccaataac ttctatttgt tccccacact
     2041 gaagatactt tactaaattt ctgtaattgt ccaatgtgcc taacccacca tgaaatagaa
     2101 cacacgctgt ttcttcttct gattctatat atcggatcac ttcataatta ttctttttat
     2161 catctccatc atccgcattc tttgttccat atgtatctac aaattcttca aatttttcta
     2221 aagttgattg atttaacaac tgacgtaaaa ttacatcata aggaatatcc atcccctgtt
     2281 cttcatttaa aaactgcata attttcccag ctatttgagc aataatcaac gaatcggctc
     2341 catactcata aaaactacga ttccattcta tagcatcaac tcccaaacta tctttaaata
     2401 tcttttcaat ttttttctgt tcttcacttc gttcatcact tataatttct tcttgttgag
     2461 agttacttcc aaattgtcca atatcactcc acctttctaa aactctccta tctatttttc
     2521 gatttgcagt caggggcaaa ctatcaatga cttgcatgtt ggaagggatc atatatcctg
     2581 caagttcctt ttttaaccca tctttaattt catctaaatc ataatgtggc atttgctttt
     2641 ttacttgttt ggcaaataag cgaattccaa acgagtcgat tgaactccct tgttctggcc
     2701 atgaatacat atccccctct cctatttcca ttaaaagttt tatccaatca ctttgtccaa
     2761 gataactggt atttttccgc aaatcatctt gtggttcctg catcaaaaat gcttgagacg
     2821 caagtatcca tgctggttca atcacagatt cacttaatac cagccatcct ttgggggcaa
     2881 tcagttcctt tagcatctgc atggtatatg gaatattttt tgcattttcg actacttcca
     2941 cagctataat catgtcaaac atatttggaa gtaagccctg ctttctataa tcttcatcaa
     3001 tattgtatat accaaattta atattcggat gctgatattt cgcctttgct gttgtaataa
     3061 aaaatgagga aacatcacta aaataatatt ctatattaga tttttctaat atacctgata
     3121 ttttttctaa tacagcgcct gttcctgcac caatctctaa aatacggatt gtcctttcat
     3181 tattgtagga aagcatattt tgaattaatt cctcaataca tgaattaata taatgtgata
     3241 ctttactatt gatataaagg tctcttacaa tcttccattc tccataagga tacaaaatat
     3301 caactggatt tacctttcca gaaagcaatc cactaatttg ctttaaattt tcctcgatat
     3361 aaaggatgaa ggtttcaggc attatctcgt tattccaagt cgaatacaaa gactctctat
     3421 aaatctttac tttctcatta atattatcag atttaagttc ataaacatct tcattcgttg
     3481 aaactaattt tccacactcg cacagcttgt ctaaccatct tttaataagc cagtgatatt
     3541 cggattttat tgactctttt tgtttcataa gcgaaaaatc aatcttttta ttctgtgtaa
     3601 gatgattttc tttcaaatat tcaagtatag aatacaaaac atactcctct aaaattgagt
     3661 ttgccagagc aatcttttct gcttcgtatt ctgcaaaaat atcattatac aattccttga
     3721 tctgcgtttg tgttatatta ctcaattgaa atgtatttat gctttctgca tcatcctgca
     3781 attttataaa agcattaagt gtagcctccg cgcctgcttt atttataacc actgccgctt
     3841 gtttgactaa tggattcttt tgcagagctg cttctacctc tcctaattca atacggtatc
     3901 ctcgcaattt tacctgctca tctcttcgac cttgaaaaat aatatctcca gattctttat
     3961 aatacccata gtcaccagtc ttatataatc gctcattttc tgtataatca ataaaatgag
     4021 aactagttgt atatgtatca ttataataac agtccgctag actttgacca ccaatataca
     4081 gttcaccact tacatataac ggacacatac gcattttctt atcaagaatt ttgaagtact
     4141 gattactcaa aggttttcca taaggaacac ttcccaaact atcatcaatc tcctcacata
     4201 agtaataatt agataggcgt ttgcgaaacg ccacaagccg cataaatacg gcattttttg
     4261 ttacctataa acaaataact cctcaccgga
//
