LOCUS       gnlProkkaPBIKMNCH_143   3573 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PBIKMNCH_143.
ACCESSION   gnlProkkaPBIKMNCH_143
VERSION     gnlProkkaPBIKMNCH_143
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 09:42:16
            Original ID  :: gnl|Prokka|PBIKMNCH_143
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3573
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..3036)
                     /NRPS_PKS="Domain: Heterocyclization (92-387). E-value:
                     1.3e-90. Score: 295.6. Matches aSDomain:
                     nrpspksdomains_ctg143_1_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (547-937). E-value: 3.2e-90.
                     Score: 294.5. Matches aSDomain:
                     nrpspksdomains_ctg143_1_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     113.4; E-value: 2.6e-34)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg143_1"
                     /sec_met_domain="Condensation (E-value: 4.3e-50, bitscore:
                     157.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3e-99, bitscore:
                     319.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFNKKMSKDDFIRELNCFFKTNIIDEKTNFLEIGISSLQIMRLIN
                     NLSKSGVKVAFGELMEKPATLEWFQIIKSHQLNMNIEPDFNLEIPLNMPFDLTEVQQSY
                     LVGRKNEQVLGGVGCHFYCEFKSAYLDINKLQNAWEKLLDIHPMLRAKFSMDDKQMICD
                     TSPNREIKVYDLRDKSNKEQKMFIDEIRERLSKQVMNVNAGEVVELHVSCLNDDNSLIH
                     FGIDLLVADLHSLRIIFRDLSDLYSERKTKYVKDNFYAYLKWKNEVSKSSKAADQKYWN
                     QKIQLLPEYPRIPMLIEPQNLKINQIGKVKYVLSLQMWDNLKKICSTKGVSPSMFFLTC
                     YALVLDKWSSNSSFIINMPLFNRKSDGIEVSNIVADFTDVLLVDVDCSEELTFYKQLLK
                     IQKSFIENSKHTDYSGVNVQKDLLKERGNGELIAPVVFSCNYGEPLLTDNFIFDFGNIS
                     NIITQTPQVILDFQIIELQDGLLLTWDFSEGLFPKNMIQEMFSELIKMVHNFNKDIWDK
                     QISTFSIPKRYLINDVSSKLLHQSLFDFSKESESRIAVIDAANGKKITYADLSNSALRI
                     AASLVEQGVEPGDMIAIMLPRSIEQIVAIYGVLYAGAAYVPISMAQPKMRTQVMLKKAN
                     IKILITLNNAVEEYKDVVSCLDIYSCNNVKPLCEPVVIDNLYPAYAIFTSGSTGTPKAV
                     LVSHRSAMNTILDINSKYNINRSDGIFAISNVTFDLSVYDIFGMASAGGHVVLVPQDEV
                     FNPTAWIEYINEYKVSIWNSVPALFDMLLSTIETNKKRLSLRRVLLSGDWVSLDIPERL
                     SRAMPKAKLTVLGGATEAAIWSNYFDVQFPIPKEWKSIPYGYPLKNQFYRIVDRKNRDC
                     PAWVEGELWIGGVGVGEKYINDEKQTEEHFIEEASMRWYKTGDIGKFWDNGVIEFLGRK
                     DFQVKINGHRIECGEIEAQLREMTEVSDAVVMPVSVGGGKILVAFINYIFSAPNQQMCL
                     LQNDKRIKIQSFLEERLIDYMIP"
     protocluster    1..3573
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:3036]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..3036
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3573
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3573
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS_motif       complement(196..261)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg143_1_0009"
                     /evalue="8.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg143_1"
                     /protein_end="947"
                     /protein_start="925"
                     /score="36.9"
                     /tool="antismash"
                     /translation="FLGRKDFQVKINGHRIECGEIE"
     aSDomain        complement(226..1395)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg143_1_AMP-binding.1"
                     /evalue="3.20E-90"
                     /label="ctg143_1_AMP-binding.1"
                     /locus_tag="ctg143_1"
                     /protein_end="937"
                     /protein_start="547"
                     /score="294.5"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="ESESRIAVIDAANGKKITYADLSNSALRIAASLVEQGVEPGDMIA
                     IMLPRSIEQIVAIYGVLYAGAAYVPISMAQPKMRTQVMLKKANIKILITLNNAVEEYKD
                     VVSCLDIYSCNNVKPLCEPVVIDNLYPAYAIFTSGSTGTPKAVLVSHRSAMNTILDINS
                     KYNINRSDGIFAISNVTFDLSVYDIFGMASAGGHVVLVPQDEVFNPTAWIEYINEYKVS
                     IWNSVPALFDMLLSTIETNKKRLSLRRVLLSGDWVSLDIPERLSRAMPKAKLTVLGGAT
                     EAAIWSNYFDVQFPIPKEWKSIPYGYPLKNQFYRIVDRKNRDCPAWVEGELWIGGVGVG
                     EKYINDEKQTEEHFIEEASMRWYKTGDIGKFWDNGVIEFLGRKDFQVKIN"
     aSModule        complement(226..2760)
                     /domains="nrpspksdomains_ctg143_1_Heterocyclization.1"
                     /domains="nrpspksdomains_ctg143_1_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg143_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(334..423)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg143_1_0008"
                     /evalue="2.00E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg143_1"
                     /protein_end="901"
                     /protein_start="871"
                     /score="29.8"
                     /tool="antismash"
                     /translation="PAWVEGELWIGGVGVGEKYINDEKQTEEHF"
     CDS_motif       complement(943..1002)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg143_1_0007"
                     /evalue="3.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg143_1"
                     /protein_end="698"
                     /protein_start="678"
                     /score="28.9"
                     /tool="antismash"
                     /translation="AYAIFTSGSTGTPKAVLVSH"
     CDS_motif       complement(1183..1218)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg143_1_0006"
                     /evalue="3.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg143_1"
                     /protein_end="618"
                     /protein_start="606"
                     /score="13.9"
                     /tool="antismash"
                     /translation="GVLYAGAAYVPI"
     CDS_motif       complement(1582..1656)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg143_1_0005"
                     /evalue="9.90E-06"
                     /label="Cy7"
                     /locus_tag="ctg143_1"
                     /protein_end="485"
                     /protein_start="460"
                     /score="18.5"
                     /tool="antismash"
                     /translation="ITQTPQVILDFQIIELQDGLLLTWD"
     aSDomain        complement(1876..2760)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg143_1_Heterocyclization.1"
                     /evalue="1.30E-90"
                     /label="ctg143_1_Heterocyclization.1"
                     /locus_tag="ctg143_1"
                     /protein_end="387"
                     /protein_start="92"
                     /score="295.6"
                     /tool="antismash"
                     /translation="MPFDLTEVQQSYLVGRKNEQVLGGVGCHFYCEFKSAYLDINKLQN
                     AWEKLLDIHPMLRAKFSMDDKQMICDTSPNREIKVYDLRDKSNKEQKMFIDEIRERLSK
                     QVMNVNAGEVVELHVSCLNDDNSLIHFGIDLLVADLHSLRIIFRDLSDLYSERKTKYVK
                     DNFYAYLKWKNEVSKSSKAADQKYWNQKIQLLPEYPRIPMLIEPQNLKINQIGKVKYVL
                     SLQMWDNLKKICSTKGVSPSMFFLTCYALVLDKWSSNSSFIINMPLFNRKSDGIEVSNI
                     VADFTDVLLVDVDC"
     CDS_motif       complement(1879..1932)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg143_1_0004"
                     /evalue="3.40E-05"
                     /label="Cy5"
                     /locus_tag="ctg143_1"
                     /protein_end="386"
                     /protein_start="368"
                     /score="16.3"
                     /tool="antismash"
                     /translation="EVSNIVADFTDVLLVDVD"
     CDS_motif       complement(1990..2049)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg143_1_0003"
                     /evalue="1.70E-06"
                     /label="Cy4"
                     /locus_tag="ctg143_1"
                     /protein_end="349"
                     /protein_start="329"
                     /score="20.9"
                     /tool="antismash"
                     /translation="GVSPSMFFLTCYALVLDKWS"
     CDS_motif       complement(2335..2376)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg143_1_0002"
                     /evalue="1.50E-03"
                     /label="Cy3"
                     /locus_tag="ctg143_1"
                     /protein_end="234"
                     /protein_start="220"
                     /score="11.9"
                     /tool="antismash"
                     /translation="IHFGIDLLVADLHS"
     CDS_motif       complement(2578..2649)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg143_1_0001"
                     /evalue="7.50E-04"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg143_1"
                     /protein_end="153"
                     /protein_start="129"
                     /score="11.8"
                     /tool="antismash"
                     /translation="LDINKLQNAWEKLLDIHPMLRAKF"
     CDS             3207..3572
                     /locus_tag="ctg143_2"
                     /transl_table=11
                     /translation="MNNFITDMHEPCLQLVGFKESAVPKSFNPVGNFYELNDNCGKGFY
                     WVYGNSNKYTITLQECTMFDEYELQYTPPKYMGINYYCSAAKIEKSPYKAISNNELHGF
                     YSTGSQYTAVYQKDIPLR"
ORIGIN
        1 aggaatcata taatcaatta atcgttcttc caaaaaactt tgaattttta tcctcttatc
       61 attttgaagt aagcacattt gttggttagg cgcagaaaaa atatagttta taaatgctac
      121 taatatttta cctccaccaa cactcacagg cataactacc gcatctgata cttctgtcat
      181 ttccctaagt tgtgcttcta tttctccaca ctctattcta tgcccattga tcttaacctg
      241 aaaatctttt cgaccaagaa attcaataac accattatcc caaaactttc ctatatctcc
      301 tgtcttatac catctcatag aggcttcttc tataaaatgt tcctctgtct gtttttcatc
      361 attaatatat ttttctccaa ctccaactcc gccaatccaa agttcccctt ctacccatgc
      421 cggacaatct ctattttttc tatctacgat tctatagaat tgatttttca aaggatatcc
      481 atagggaata gatttccatt cttttggaat cggaaactga acatcaaaat agtttgacca
      541 aattgccgcc tccgtagccc ctcccaaaac agttaacttt gctttcggca tagcacgact
      601 aagacgttcc ggaatatcca acgaaaccca atcccctgaa agcaaaacac gacgtagaga
      661 taaccttttc ttatttgttt caatcgtact caacagcata tcaaataaag caggaaccga
      721 gttccatatg cttactttat attcattaat atattctatc catgccgttg gattgaatac
      781 ttcatcttga ggaacaagca caacatggcc gccagcactt gccataccga aaatgtcata
      841 caccgataaa tcgaatgtaa cattggagat tgcaaatatt ccatcactcc tatttatatt
      901 atattttgaa ttaatatcca aaatcgtatt catggctgaa cgatgactca ctaatacagc
      961 ctttggtgtt ccagtcgatc ccgatgtaaa tattgcatat gcaggataga gattgtcgat
     1021 tacaaccggt tcgcacagag gtttcacatt attacatgaa tagatatcta aacatgacac
     1081 gacatcttta tattcctcaa ctgcattatt tagtgtaata agtattttta tatttgcctt
     1141 ttttagcatt acctgagtcc gcattttggg ctgagccata gaaataggta cataagcagc
     1201 cccagcatat agtacaccat aaatagcaac tatctgttct atgcttcttg gaagcattat
     1261 cgctatcata tctcctggtt ctactccctg ttctactaaa ctcgccgcaa tccttaatgc
     1321 actattggac aaatcagcat acgttatttt tttcccgtta gcggcatcaa taaccgcaat
     1381 cctactttct gattccttag aaaaatcaaa aagtgactga tgcaataatt tagaagatac
     1441 atcattaatt aaatatcttt tcggtatgct gaatgtagaa atttgtttat cccaaatatc
     1501 tttattaaaa ttatgaacca tcttaatcaa ctcagaaaac atttcctgaa tcatattctt
     1561 tgggaacaat ccttctgaaa aatcccatgt taatagaagc ccgtcttgaa gttcaattat
     1621 ctggaaatct aaaattacct gtggtgtttg cgttattata ttagatatat ttccgaaatc
     1681 gaatataaaa ttatctgtta ataatggttc accataatta caagaaaaga caaccggagc
     1741 aatcaactct ccatttcctc tttcttttaa taaatctttc tgtacattta cacctgaata
     1801 atccgtatgc ttactattct ctataaaaga tttctggatt ttgagcaatt gtttataaaa
     1861 tgttaactct tcactacaat caacatcaac taataacaca tctgtaaaat cagctactat
     1921 atttgaaacc tctatcccat cactcttcct attaaaaagg ggcatattta taataaatga
     1981 agaatttgag ctccatttat ctaacaccaa tgcatagcag gtaagaaaaa acatagacgg
     2041 tgacacacct ttagtcgaac aaattttttt gagattatcc cacatttgca gacttaaaac
     2101 atacttcact ttgcctatct gatttatttt tagattttgc ggttctatca gcatagggat
     2161 tcgagggtat tcaggcaata gctgtatttt ttgattccaa tatttttgat ctgctgcttt
     2221 acttgatttt gacacttcat ttttccattt taaatatgca taaaagttgt ccttcacata
     2281 tttagttttt cgttctgaat ataaatcact caaatcacgg aatattattc gcaaactatg
     2341 taaatcagct actaataaat ctattccaaa atgaatcaac gagttatcat cattcaaaca
     2401 gctgacatgt aattcgacaa cttctcctgc gttcacgttc attacttgct tagacaatct
     2461 ttcacgaatt tcatcaataa acatcttttg ctctttgtta cttttgtctc ttaaatcata
     2521 tactttaatt tcacgatttg gtgaagtatc acatatcatc tgtttatcat ccatagaaaa
     2581 ctttgcacga agcataggat gaatatccaa taatttttcc catgcatttt gtaatttatt
     2641 aatatccaaa tatgcacttt tgaactcaca ataaaagtga catcctactc cacccaaaac
     2701 ctgctcattc ttccttccaa ctaaataaga ttgctgtacc tcagttaaat cgaaaggcat
     2761 atttaaaggt atttctaaat tgaaatcagg ttctatattc atatttaact gatgagactt
     2821 aattatctga aaccactcta gtgtagccgg cttttccata agttctccaa atgctacttt
     2881 tacaccgctt ttggataaat tgttaatcaa acgcatgatt tgcaaagacg agatgccaat
     2941 ttctaagaag tttgtttttt cgtcgataat gttcgtttta aaaaaacagt tcaattctcg
     3001 gataaaatca tctttactca tttttttatt aaacattttt gttcctcctt gtatatctca
     3061 attctttttg atataataat ctccaataca gttagacatt tctaactata tttcactttt
     3121 tacctaattt caacatttat aaagaaagca tgtactatcg aaccattctt ttgtacaaac
     3181 agaccatcaa aaagggagga cctaacttga acaattttat tactgatatg catgagccat
     3241 gtttacaatt ggtaggtttt aaagagtctg ccgtacctaa atcatttaac ccagttggaa
     3301 atttttatga actaaatgat aattgcggga aagggtttta ctgggtatat ggcaattcta
     3361 ataaatatac aattacatta caggaatgta ctatgttcga tgaatatgaa cttcaatata
     3421 cccctcccaa atacatgggt attaattatt attgttctgc tgccaaaatt gaaaaatctc
     3481 cttataaagc aataagcaat aatgaattgc atggctttta cagtacaggt tcacaataca
     3541 ctgctgtcta tcaaaaagat ataccattac gag
//
