LOCUS       gnlProkkaPBIKMNCH_326  13043 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PBIKMNCH_326.
ACCESSION   gnlProkkaPBIKMNCH_326
VERSION     gnlProkkaPBIKMNCH_326
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 09:42:16
            Original ID  :: gnl|Prokka|PBIKMNCH_326
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13043
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13043
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1:3043]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..3043
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..13043
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13043
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             2..3043
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     850.5; E-value: 3e-257)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg326_1"
                     /sec_met_domain="DUF4135 (E-value: 5.9e-105, bitscore:
                     340.8, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.2e-58, bitscore:
                     187.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILGKDVIELIDKAYGVSIEQILFSEYSLNHKYISFATLNQEYS
                     DMCNEKAISYLTKKGTKVLFDQFVLRFLGYGKRVLERKSRKGYIVKVVQDCFLKNLAER
                     ILDVSLSTLIFEMYLAKEQGELRGNDEAKEYKDYNQRFLGNDKYIKELFSIYPGLKRML
                     IELMENLANNYILLQERMEKDTLLLEDKFGGKKGWTEVKNIRTSGSDSHKKGNSVFLIQ
                     FQDGRKIVYKPHGLKVEKAYQSFLEFISSNCKKDFKQFLILDCGDYGWEEFVVNLPCNS
                     EAEVRNYYYRIGVLVFCNYILNVNDIHTENLIANGGYPVVVDAETVLDNKREKKKKSGR
                     EKIYDKIHESVLYSGVLPFYKYTKNGKGINMSALNGQEGEQYPILIPRLKNAGTSNMHY
                     EYERPITQASNNLLRLGEKVKEPNQYIDEICEGFFDAYTFCLDNKKLILNYVSIFENIE
                     VRHLVQDTQRYSMLLHTSYNPDFLQDAKDRQLFLCAVLKNVEQMQGNMEIAKLEIKDML
                     NMDIPYFYSNTSKEDLYGSEGEVVKNYFAESSIQHLRNKICSMGKKDREEQIRFIKIIL
                     TDLNDVKVEKPKKDINELCISRSDNEHGQKEYKKNAILKILHTLEQKAFYGDDGQDINW
                     IGITSIGNSENSSWNIQPLGVYLYEGLGGIALFYNALQQSDFDVDLSAACKAFETMMFQ
                     YTDDMLERSTDLEKESSGAYAGEASVIYVYEVLYKITGKQKYLEYAEKHCKILEYALKA
                     DENNDLIYGNAGAVIVLLNLYHLAQKDIYLQLACEAGNILIKNQNKGKWCCGNGQSLSG
                     LSHGITGIIYALTKLNNEQFHIEYQKAIHSGLIYENTMYSDKYNNWLDNREEAKKEENS
                     DNRCMAAWCHGAPGILLARSKMYNLVKDSSDYITVQCDIERALFATKMYGFTDNDCLCH
                     GNLGNTEILLEYSKECNDEEVRHMMLSARTQIAMDIINENYDCARSYLHGYKIPGFMTG
                     ISGMGYSLLRDLYPELPCILALEI"
     CDS             3086..5182
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 257.4; E-value:
                     4.6e-78)"
                     /gene_kind="transport"
                     /locus_tag="ctg326_2"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.5e-31, bitscore:
                     97.2, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKKVHYVSQLGSMDCGIACLTMILNYYGCKSDIVDIGAEIQIG
                     RDGMTLAQMKELAEKYGFKFAAYQYNHEEKNLIEYLPAILCNDSHYVVVDKTKKKGKYI
                     LFDPANGKRVVDFLELKNGYKDILVSVIPSRNIKKIKKTKFKIEVKFSQFMIAIMLMLM
                     CQLITLAVPMVVQKVIDSLSSAHITIHIWKITLLVLLIMCAHFVLSLLRQKILLNINMK
                     LFKTMISNMIHKIFRLDVSFFEWHSAGDIGNRFNSINQLNDILTNGFINIIIQGITSLV
                     CLAVMTSISPYLTAFVLVVSIIQIAIMILLNGKNLIKTKEYIYSQSTIQGELIDTLENI
                     MEIKCMGMDNAVKSNLQNSYSKLIERFKGKTRISNLMNSFSSTLNLIFPLMIYVIGSYS
                     VKQGGLTIGQLIAYATLVGYFTAPFTTVVLLLPSINSIKEVLLRYKELMIFRENYHTGV
                     LVPGKFENLKISSVSYCYNSGQAYALNNVSLDLRRGERIAIVGLSGSGKSTLIKAILGA
                     VDINQGCIEINNYDIRSMSKEQIYKWFSVVTQNPMCLNASIRKNIDIIGDAPDEKIWKV
                     LDIVALKEEVLSMPLGLDTLVGEGGQNISGGQKQRIAIARALLSDTEVVIFDEATSNLD
                     QLTEKKIYDNLRSTNKTQIIITHRLSSIRDTDYIYVLNRGSIIEQGTHLDLMKKKGWYF
                     ESIQ"
     CDS             5237..5902
                     /locus_tag="ctg326_3"
                     /transl_table=11
                     /translation="MKKKEIVIGVSVLISASLPISVYAASNESMSSRGFIIDETNEFED
                     IVKQILDVKSKHPEWSEQQISDFMDQIHAIKKDGVIDIWNALTSSEKKLVIRYPFDALK
                     VNKAKEIATKQTERKFGKNGLGDRSDAFRHGIWNAEMTVLIGSEKAELFATAHEDKDTT
                     GNESDGYTKDEHKKMDLHNNEIGRKLGADNLSAPEEKMAEIIYDEIMREDSLFVWLHE"
     CDS             complement(6583..7512)
                     /locus_tag="ctg326_4"
                     /transl_table=11
                     /translation="MANETMNLNTPILTLDSDTVLETAQSKADLIWHDIQNAYRTRKIL
                     TGILGGIEKTEAGSLIAIIYYKDYRAVIPISEMMINLIQDETHDYGDFSLRQNKVLNNM
                     LGCEIDFVIKGLDTKSRSIVASRKDAMLKKRQIFYFDQDSSGQNKIHEDRIVQARVIAV
                     AEKVVRAEIFGVETSILARDLSFDWLGDARERFQVGEHILVRILAIQGDSPETLSIHAD
                     VKSVEGNTSKENLKNCRVQGKYAGTVEDIHKGTVFVRLELGVNAIAHSCYDSRTVGKKD
                     KVSFVVTHIDEERNVAVGIITRIIKQNI"
     CDS             complement(7538..9544)
                     /locus_tag="ctg326_5"
                     /transl_table=11
                     /translation="MNRKWWKFLFLLPISVCTLYAGGYAAQFIKNYQEWTSAGNFAGNG
                     TYPQAASLHPLVCFHTALTDFPYNLYGIFLCLVLFGLLTFLLMRMGYDRNGEISDHDRN
                     LNYSTKGTYGTSGFMTPDEMMKVLELTGDVKKNKGTILGKLNGKAVCLPYQTRMNKNIA
                     VYGASGSMKSRAFARNMIFQCVARGQEGNNASGESLIITDPKSELYESMSAYLENEGYV
                     VKAFNLVNPENSDSWNCLGEINGQETMAQVFADVIIQNTGSGKGDHFWDNAEMNLLKAL
                     VLYVDQGFPPEARNIGQVYKLLTMSSEKELNSLFDLLPVSHPAKVPYCIYKQASDTVRS
                     GVIIGLGARLQVFQNKLIRQITSYDEIDLTLPGKQKCAYFCITSDQDSTFDFLSSLFMT
                     FIFIKLVRYADKYGEEGKLPVAVHILADELANTGAILELNKKISVIRSRNLSISCIFQN
                     LPQMQNRYPYNQWQEIIGNCDTQLFLGCTDEVTATFISNRSGDVTVGVSSEAKQLNSWR
                     VSDYTPEYRQTKSIGKRKLLTPDEILRLPLDTALVILRGQKVLKVEKYDYTLHPDAKKL
                     TPRKASEHIPEWRKNGSSEETEYRPQPSPGSAKRKRRSSSASIAKQKPHFTSEPVYQEP
                     TPDDFMEDFFQENFIEDSPDSGMVPLDKDSIMS"
     CDS             complement(9534..10640)
                     /locus_tag="ctg326_6"
                     /transl_table=11
                     /translation="MIKTDSIKYQLLEMVGLCGEFPSGQLNRLIESDSYAEKVVTDLKQ
                     SKLIRTHYKDGLRGYRLTKRAKELLLSQNPCRFQNYLTGNAETNLIRSELPRRLRLHQK
                     AETYLTLSHAGIPFFPDEKPLLFSESSEAATFPVRSLPLFYSSREIKNLGASTTKIKNS
                     RCIGILMAPHCVYAVYNTGNTLLKWEYKTEVRLNAFLQHYLQGLPYHGPPTVYAIMTGS
                     DMDMAFRLLTSTGGYKKTLFMLDTSYEHFYFLPNNSYGEYLLRLLVQPQRMMQLNQLLL
                     SDCFPQREDLPIEHDGIDSQENPILLAYDFDMQRINRFNTGLNVYGLSGNLICFDFQLP
                     CLKKYLTADIHFSSIDFQKFKRRFFNEP"
     CDS             complement(10780..11445)
                     /locus_tag="ctg326_7"
                     /transl_table=11
                     /translation="MNTKTVFDRLQSIDDEVQKLHNTIFALKTTDIQAYADKYEELSIS
                     AALRSERIACQLRNLVYTTTDTGKKDYLKQAAAVQGIKISFSNSVLSITMPGLLPKRKL
                     RTNTAFLHEPLNLALQTYVTEHSIPLYKRCVVCFSQIYDQSLSLQRIRDYDNLEFKQIL
                     DTIASYVLVDDTGLFCDSYHTTELGNYDHTVIFVMEPEIFPGWLKDRKESIKTISEIS"
     CDS             complement(11453..11983)
                     /locus_tag="ctg326_8"
                     /transl_table=11
                     /translation="MKTRNEIYQGEGAQLLRFITTYHSLQYEQVLRLFSKNRESIKSLI
                     TSLVKQKRIIYDKENGLLFDSQESANNPDYGMIASFWVLLDFKTAIVYHTDGEFPVKLN
                     FFSKDEWYEVLYVPQEQEYLINHVMESQTKSDAKRLVVLETEEQAAKIHITGVIAFCLV
                     DSSTGSVSYYAKK"
     CDS             12384..12557
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg326_9"
                     /transl_table=11
                     /translation="MRKFDRTNMKYNNPAGDLLTELEAADLTSNKVDSLASSGVVCTIS
                     VECGSIFTLACC"
     CDS_motif       12384..12458
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MRKFDRTNMKYNNPAGDLLTELEAA"
                     /locus_tag="ctg326_9_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12459..12557
                     /prepeptide="core"
                     /locus_tag="ctg326_9_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="3061.5"
                     /monoisotopic_mass="3059.5"
                     /core_sequence="DLTSNKVDSLASSGVVCTISVECGSIFTLACC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRKFDRTNMKYNNPAGDLLTELEAA"
                     /leader_location="[12383:12458](+)"
                     /alternative_weights="3079.5"
                     /alternative_weights="3097.5"
                     /alternative_weights="3115.6"
                     /alternative_weights="3133.6"
                     /alternative_weights="3151.6"
ORIGIN
        1 gaataacatt ttaggtaaag atgttattga attaatagat aaggcttatg gggtttctat
       61 agagcagata ttattttcag agtattcgtt aaatcataaa tatattagct ttgcaacgtt
      121 aaatcaggaa tattctgata tgtgtaatga gaaggctata tcctatttga ctaaaaaagg
      181 aacaaaagta ttatttgatc aatttgttct caggtttctg ggatatggga aacgggtttt
      241 agaaagaaag agtagaaaag gatatattgt taaagtagtt caggactgtt ttttgaaaaa
      301 tttagcggaa aggattttag atgtttcttt aagcactctt atttttgaaa tgtatttagc
      361 aaaagaacaa ggagaactta gaggaaatga tgaagcaaaa gaatataaag actataatca
      421 gagatttctt ggtaatgata agtatataaa agaattattt tccatatatc caggtcttaa
      481 aagaatgctg atagaattaa tggaaaattt ggcaaataat tatatattat tgcaggaaag
      541 aatggaaaag gatactttac ttttagaaga taaatttggt gggaaaaagg gctggactga
      601 agtaaaaaac ataagaacga gtggttcaga ttcacataag aaaggaaata gtgttttttt
      661 aattcagttt caagatggaa gaaaaatagt ttataaacca cacggactga aggtggagaa
      721 agcatatcag tcatttttgg agtttatttc ttccaattgt aaaaaggact ttaagcaatt
      781 tttgatttta gattgtgggg actatggatg ggaagaattt gtagttaatc ttccttgtaa
      841 cagtgaggct gaagtcagga attattatta tcggatagga gtgcttgttt tttgcaatta
      901 tatattaaat gtcaatgata tacatactga aaatcttatt gctaatgggg gatatccggt
      961 tgttgtagat gccgagactg tcttagataa taaaagggag aaaaagaaaa aatcaggtag
     1021 agaaaaaatt tacgataaga tacatgaatc agtgttgtat tctggagtac tgccttttta
     1081 taaatacact aaaaatggaa aaggtataaa tatgagtgct cttaatggcc aagagggaga
     1141 gcaatatcca atactgattc caagattaaa aaatgctggg acatcaaata tgcattatga
     1201 atatgaaaga cctattactc aagctagtaa taatttactg agactggggg aaaaggtaaa
     1261 agaacctaat cagtatatag atgagatatg cgaaggtttt tttgacgcat atacattttg
     1321 tttggacaat aagaagctta tattaaacta tgtttcgata tttgaaaata ttgaagttag
     1381 gcatttagtc caagatactc agcggtattc catgctattg cacacatcat acaatccgga
     1441 ttttcttcaa gatgcgaaag ataggcaact atttttgtgt gcagtgttaa aaaatgtgga
     1501 acagatgcaa gggaatatgg aaattgcaaa actggaaata aaggatatgc tgaatatgga
     1561 tattccatat ttttatagca atacttcaaa agaagatctt tatggatcag aaggggaagt
     1621 ggtgaagaac tattttgctg agtctagtat tcaacatctt agaaataaga tctgttctat
     1681 gggcaagaaa gatagagaag aacagattag atttataaaa ataattttaa cagatttgaa
     1741 tgatgtaaaa gttgagaaac ctaaaaaaga tataaatgaa ctttgtataa gtagaagcga
     1801 taatgaacat ggacaaaagg aatataaaaa aaatgccata ttaaaaattt tacatacatt
     1861 agagcaaaaa gctttttatg gtgatgatgg gcaggatata aattggatag gaataacatc
     1921 tattggaaat tctgaaaatt cttcttggaa tatccaacca ttaggggttt atttatatga
     1981 aggattagga ggaattgccc ttttttataa tgcactacag caatcagatt ttgatgtgga
     2041 tttgtcagca gcctgcaaag catttgagac catgatgttt caatataccg atgatatgtt
     2101 ggaacgatcc acggatttag aaaaggaaag tagcggtgct tatgcggggg aagcttctgt
     2161 tatatatgta tacgaagttt tatataagat aacaggaaaa caaaaatatt tagaatatgc
     2221 agaaaaacat tgcaaaattt tagagtatgc attgaaagca gatgaaaata atgatctgat
     2281 ttatggtaat gcaggtgccg ttattgttct tcttaatctt tatcacttag ctcaaaagga
     2341 tatatatttg caattggcgt gcgaagcagg gaacattctt ataaaaaatc agaataaggg
     2401 taagtggtgc tgcggaaacg ggcagagctt atctgggctg tcacatggaa ttacaggtat
     2461 aatttatgct cttacaaagt taaataatga gcaatttcat attgaatatc aaaaggcaat
     2521 acactctgga ttaatatatg aaaataccat gtattctgat aaatataata attggttaga
     2581 caatcgggag gaggcaaaaa aagaagaaaa ctctgataat agatgcatgg cagcatggtg
     2641 tcatggggca ccagggattt tattggcaag aagtaagatg tataacctgg ttaaagacag
     2701 tagtgattat ataacagtac aatgtgatat tgaacgtgca ctatttgcga caaaaatgta
     2761 tggatttaca gataatgact gtctatgtca tgggaatttg gggaatacag aaatattact
     2821 tgaatattca aaagaatgta atgatgaaga agtaagacat atgatgttgt ctgcgagaac
     2881 acaaattgct atggatatta taaatgaaaa ttacgattgt gcaaggtctt atttgcatgg
     2941 gtataagata ccaggattta tgacaggaat ctcaggaatg ggatactctc tattaagaga
     3001 tttgtaccca gaattaccat gcattttggc tctggagatt taggagcgta attgctaagt
     3061 aatatttaac aaagggagga acttgatgtt tcaaaaaaaa gtgcattatg tttcacagct
     3121 aggaagcatg gattgtggca tagcatgtct gacaatgatt cttaattatt acgggtgtaa
     3181 aagtgatatc gtggacatag gggcagagat tcagattggc agagacggta tgaccttagc
     3241 tcaaatgaaa gaattagcag aaaagtatgg atttaaattt gctgcatacc agtataatca
     3301 tgaagaaaaa aacttaatag agtatcttcc agccattttg tgtaatgatt cccactatgt
     3361 ggtagttgat aaaactaaga agaaaggaaa atatattctg tttgatccag caaatggaaa
     3421 aagagttgtc gattttttag aattaaaaaa cggatacaag gatattcttg tatccgttat
     3481 tccaagtaga aatattaaga aaataaaaaa aaccaaattt aaaatagagg taaaattctc
     3541 tcaatttatg attgcaatta tgttgatgct tatgtgtcaa cttattacat tagctgttcc
     3601 aatggttgtg caaaaagtaa tagatagttt atcttctgcc catattacaa ttcatatatg
     3661 gaaaattaca cttttagttc ttctgattat gtgtgcccat tttgtattga gcttactaag
     3721 acagaaaatt ttattgaata ttaacatgaa actttttaaa acaatgattt ctaatatgat
     3781 tcataaaatt ttccgtttgg atgtaagttt ttttgaatgg cattccgcag gtgacatagg
     3841 gaaccgtttc aatagtataa atcagttgaa cgacattctt accaatggat ttataaacat
     3901 tataatccaa gggattacat ccttggtatg tttagctgtt atgaccagta tatctccata
     3961 tttgactgca tttgttctag ttgtttctat tatacagatc gccataatga ttttattaaa
     4021 tggtaaaaat ctcataaaga cgaaagagta tatatactca cagagtacaa tacagggaga
     4081 actgatagat actctggaga atataatgga aataaaatgt atggggatgg ataatgcagt
     4141 taaatcaaat ttacaaaatt cttatagtaa gttaatagaa agattcaagg gaaaaactcg
     4201 aattagtaat ttgatgaata gtttttcctc aaccttaaac ttgattttcc ctttaatgat
     4261 ttacgtgatt ggaagttata gtgtgaagca aggagggtta acgataggac aacttatagc
     4321 ctatgcaacc ttagtgggat attttacagc accttttact accgttgtat tgttgttacc
     4381 gagtatcaat agtattaaag aagtgctttt acgttataag gaactaatga tttttagaga
     4441 aaattatcat acgggagttc ttgtacctgg aaaatttgaa aatttaaaaa taagttcggt
     4501 ttcatattgc tacaatagtg ggcaggcata cgcattgaat aatgtttctc ttgatcttag
     4561 gcgaggcgag agaattgcta ttgttggttt atcgggtagt ggaaaatcaa ccttgataaa
     4621 agccatactg ggtgccgtgg atattaatca aggatgtatt gagataaata attatgatat
     4681 cagatcaatg tcgaaggaac agatttataa atggttttca gtagttactc aaaatcctat
     4741 gtgcttaaat gcaagtataa gaaagaatat tgatattata ggtgatgctc cggatgagaa
     4801 aatatggaag gtactagaca ttgtagcatt aaaagaggaa gttttaagta tgccgttggg
     4861 attggataca cttgttggag aaggaggaca aaatatttca ggtggtcaaa aacagcgtat
     4921 tgccatagca agagctctgc ttagcgatac ggaggtagtt atttttgatg aagctaccag
     4981 taatctggat cagcttacag aaaagaaaat ttatgataac ctaaggtcta ccaataaaac
     5041 gcaaattatc attactcata gactttcctc tattcgagat acggattata tctatgtatt
     5101 gaacagggga agcatcattg aacagggaac acatttggat ttgatgaaga aaaagggatg
     5161 gtattttgag agtattcaat gacagatagg aattaaatta tgatatgaaa agccattgta
     5221 tggggaggta ttacagatga agaagaaaga gatagttatt ggggtgagcg tactgattag
     5281 tgcatcactt cccatttcag tttatgctgc ttcaaatgaa agtatgagtt ctagaggttt
     5341 tataattgat gaaactaatg agtttgagga tatcgttaag caaattttag atgttaagtc
     5401 aaaacatccg gaatggagtg aacagcagat aagtgatttt atggatcaga ttcatgctat
     5461 taagaaagat ggcgtcatag acatttggaa cgcacttact tcttctgaga aaaaattagt
     5521 gattcgatat ccgtttgatg cactaaaagt caataaagca aaggaaattg ccactaaaca
     5581 aaccgaaaga aaattcggaa aaaatggttt gggtgacagg agtgacgcat ttagacacgg
     5641 aatatggaat gccgaaatga cagttttgat aggaagtgaa aaagcagagc tttttgcgac
     5701 agcacatgaa gataaagata ctactggaaa cgaaagcgat ggatatacaa aagatgagca
     5761 caaaaaaatg gatttacata acaatgaaat agggaggaaa ttaggtgcag ataacctatc
     5821 tgcaccagaa gagaaaatgg cggaaatcat atatgacgag ataatgagag aagattcgct
     5881 gtttgtatgg ctgcatgaat gaaaaagtta gaacgtatga actgaaatga aatatatctc
     5941 taagacagtc gcagatattt tattgatgtt tagatatctg tgactgtttt tgaatagaaa
     6001 taatagtcgt taaaaatgtc tgctctgact aaatttgaaa gaagaatcag aatgagaacc
     6061 aagtactaat gtatagccat gaattagatg tgaaatctgt taaatgatgg tcaaatgaga
     6121 atgagggggc tgtagaaaaa tatttatcaa catattattt gtcgatttag tttaagtaat
     6181 gacaataaca ataataaagg gggacttgat ttctcatatc ccccagtgta taatctaatt
     6241 aagaaaggta atcagatgca agatctgatg ccctcagtaa aatttaattt ttttctatgt
     6301 taagacatag catccatcaa actttctcag ggtttatcgt ggatgctatt tcttatcatg
     6361 tcgattatct atgtaagtca gagccgcaaa aactactaaa agcaatgtga gtacttccat
     6421 tgtgttcatg ggcatcaccc tcctttaaaa actagagggc tggtcgaaat tgcatccgca
     6481 tctctttctc gattagctat actcgctcag tatagcatgg aatatcttgt atcgcaataa
     6541 gaaatggatg tagtgagctc cttttcatat tgcttttggt aatcagatat tttgtttgat
     6601 aatccttgta atgatgccaa cagcaacatt ccgttcttca tcaatatgtg tcacaacaaa
     6661 ggacacctta tctttcttcc caacggtgcg gctgtcgtag caactgtgag caatggcgtt
     6721 gacacccaat tctaaccgga caaaaacagt tcctttgtgg atgtcttcca ccgtaccggc
     6781 atattttcct tgtacccgac aatttttcag attttctttg ctggtgttgc cttccacgct
     6841 ttttacatct gcatggatag agagcgtttc cggggaatct ccctggatag ctaagatccg
     6901 gaccagaata tgttccccta cctggaatcg ttccctggca tcacccagcc agtcaaaaga
     6961 cagatctctt gcaaggatgg aagtttctac accaaagatt tctgcccgga ctactttttc
     7021 agcaacggca atgactctgg cctgcacaat acggtcttcg tggattttat tctgtccgga
     7081 agagtcctga tcaaaataga aaatctgacg tttcttcagc atagcatctt tccggctggc
     7141 aacgatgctt ctggatttgg tatccagtcc tttgattaca aagtcgattt cacaaccaag
     7201 catgttatta aggactttgt tctgtctaag agagaaatct ccgtaatcat gagtttcatc
     7261 ttggatcaga ttgatcatca tttccgagat agggatgact gcccgataat ctttatagta
     7321 aataattgct attaagctgc cggcttcggt cttttcaata cctcccagaa tgccggtgag
     7381 aattttccgg gtacgatagg cattttggat gtcatgccag attaaatccg cttttgattg
     7441 agcagtttct aatacagtat cggagtcaag ggttaaaata ggggtgttca ggttcattgt
     7501 ttcgtttgcc ataaatgtta tctcctttca aaatgtgtta tgacatgatg gaatctttat
     7561 ctaaaggaac catgccagag tcgggggaat cttctataaa attttcctga aagaaatcct
     7621 ccataaaatc atcgggagta ggttcctgat aaacgggttc ggatgtaaaa tgtggtttct
     7681 gttttgctat tgacgcagaa gatgaacggc gtttcctttt ggctgatccg ggtgagggct
     7741 gtggtcgata ctctgtttct tccgaagacc catttttgcg ccattcaggt atgtgttccg
     7801 atgcttttct tggtgtcagc tttttggcat ctggatgcag ggtataatcg tacttttcta
     7861 cttttaggac tttttgccca cgtaggataa ccaaagcagt atcaagcggg agccgcaaga
     7921 tttcatctgg tgttaagagt tttcgtttgc cgatagattt tgtctgccgg tattccggtg
     7981 tatagtcgga tacccgccag ctattgagct gcttggcttc gctgcttacc cctacggtca
     8041 catcgccgct gcggttgctg ataaaggtag cagtaacttc atctgtgcag cccaaaaaga
     8101 gctgggtatc acagttgcca atgatttcct gccattggtt ataaggatag cggttctgca
     8161 tctggggcaa attctgaaag atgcaggaaa tgctgagatt ccggcttcgg attacactga
     8221 ttttcttatt cagttccagg atagctccgg tgttggcaag ctcatcagcc agtatatgta
     8281 cagcaacagg aagttttcct tcttctccat acttatctgc ataacggacc agtttgatga
     8341 agatgaaggt cataaacagg gaagataaaa aatcgaaggt gctgtcctgg tctgaggtaa
     8401 tgcaaaagta agcacatttc tgtttccctg gaagtgtcag atcaatctca tcataagagg
     8461 taatctgccg aatgagttta ttctgaaata cctgaagtct ggcacccaat ccgataataa
     8521 ctccgcttcg cacggtatca ctggcttgtt tgtagatgca gtaaggaact tttgctggat
     8581 gggacactgg gagcagatca aaaagactgt tcagctcctt ttcggaactc atggtcagca
     8641 gcttataaac ctgtccaata tttctggctt ccggcggaaa gccctgatct acatagagaa
     8701 ccagggcttt tagcaggttc atctccgcat tatcccagaa atgatctcct tttccggaac
     8761 ctgtattctg gataatgaca tctgcaaata cctgagccat cgtttcttgt ccattgattt
     8821 cacccagaca attccaacta tccgagtttt ccggattgac cagattaaat gcttttacta
     8881 catagccctc attttccaga taagcagaca tgctttcata gagttcgctt ttgggatcgg
     8941 taatgattaa actttccccg gaagcgttgt tgccttcctg ccctctggcg acacactgga
     9001 aaatcatatt cctggcaaat gccctggatt tcatggaacc gctggcacca tacacggcga
     9061 tatttttatt cattcgtgtt tgatatggaa gacatacggc tttgccattt aattttccta
     9121 aaatggttcc tttatttttc ttgacatctc cggtcagttc caaaactttc atcatttcat
     9181 ctggagtcat gaatccggat gtaccgtagg ttccttttgt agagtaattt aagttccggt
     9241 catggtcact aatttccccg tttctgtcat atcccatacg cataagtaaa aaagtaagaa
     9301 gcccaaagag aaccaggcaa agaaaaatcc catacaaatt gtatgggaaa tcggtaaggg
     9361 cggtatgaaa gcagaccaat gggtgtaaag aagctgcttg cggataggtt ccgttgccgg
     9421 caaagtttcc ggcagaagtc cattcctgat agtttttaat aaattgtgct gcgtatcctc
     9481 cggcatacag agtgcagacg cttatgggaa gcaaaaacag gaacttccac catttacggt
     9541 tcattgaaaa acctcctttt aaacttttga aaatcaatgc tggagaagtg tatatctgca
     9601 gttaggtatt ttttcaggca gggaagctga aagtcaaagc aaatcaggtt cccggatagc
     9661 ccatatacat ttaatccagt attgaagcgg ttgatacgct gcatgtcaaa atcatacgca
     9721 agcaaaatag gattttcctg gctgtctatt ccatcatgtt caattggcag atcctcacgc
     9781 tggggaaaac agtcggacag tagtagctga ttgagctgca tcatacgctg gggttgtacc
     9841 aataaacgga gcaggtattc tccgtagctg ttattgggca ggaaatagaa gtgttcatac
     9901 gaagtatcca gcatgaacag tgtttttttg tatccaccgg tactggtaag gagccggaaa
     9961 gccatatcca tatcactgcc agtcatgatg gcataaacgg taggtggccc atggtaagga
    10021 agtccctgaa gatagtgctg caaaaaagca ttgagtcgga cttccgtttt gtattcccat
    10081 tttagaagtg tatttccggt attataaaca gcatagacac agtgaggagc catcaggatt
    10141 cctatacaac gggaattttt aattttggta gtggatgctc caagattttt tatttctctg
    10201 gaagagtaaa acagaggaag gcttcgcaca ggaaacgtag ccgcttcgct ggattcagaa
    10261 aaaagcagcg gcttttcatc tggaaagaat gggattccgg catgtgaaag cgttaaatag
    10321 gtttctgctt tttgatgaag tcgcagccgt cttggtaatt cactacgtat gaggttggtt
    10381 tctgcatttc cggttaaata gttttgaaaa cgacagggat tttgcgaaag cagcagttct
    10441 tttgcccgtt tggtaaggcg ataacctcgt aggccatctt tatagtgtgt tcttataagc
    10501 ttactctgct ttaaatctgt aaccaccttc tctgcatagg aatcactctc aatcaatctg
    10561 ttaagctgtc cggaagggaa ttccccacat agcccaacca tttccaaaag ctgatatttt
    10621 atagaatcgg tttttatcaa ataagcatca cctcagttcg atttttacct atgacagcct
    10681 atacttgggt aaagtaaggg cggtattaag cataaaaaat gcaaagaata tggcttcttt
    10741 gcagaaaaat tacccatatc ggaaaaagaa agaaaaatat caggaaattt ccgatatggt
    10801 tttgatagac tcttttctat ctttcagcca gccaggaaag atttccggtt ccattacaaa
    10861 gataacggtg tgatcgtaat tccccagttc cgtagtgtga taggagtcgc aaaagagtcc
    10921 cgtatcatca accagaacat aggaagcgat agtatctaaa atctgtttga actccaaatt
    10981 atcgtaatca cgtatccgtt gtaaagaaag gctctggtca taaatttgac taaaacagac
    11041 cacacatctt ttatataacg gaatagaatg ttctgtcaca taagtctgca aggcaaggtt
    11101 taatggctca tgtagaaaag cggtgttggt tcgcaattta cgtttgggca gtagtcctgg
    11161 catggtaatg gaaagaacac tatttgaaaa agagattttg attccctgca cagccgcagc
    11221 ctgtttcaga tagtctttct ttccagtgtc agttgtggta tataccagat ttctgagctg
    11281 gcaggcaatc ctttcagaac gtagggcagc actgatactc agctcttcgt atttgtcggc
    11341 atacgcttga atatctgttg ttttcaatgc aaaaatagtg ttgtgaagtt tttggacttc
    11401 atcatcaatg ctctgtaaac ggtcaaaaac agttttggtg ttcatacata cctcatttct
    11461 ttgcataata gctgacagat ccggtagagg agtctacaag gcaaaaggca atcacgcctg
    11521 tgatatgaat ttttgcagcc tgttcttctg tttctaatac aaccagccgt ttcgcatcgc
    11581 tttttgtctg gctttccatg acatgattga taagatattc ttgttcctgg gggacataga
    11641 ggacttcata ccactcatct ttagagaaaa agttcagttt cacaggaaat tcaccgtcag
    11701 tatggtacac aatggctgtt ttgaagtcca aaagcaccca aaaggatgca atcatgccat
    11761 aatcaggatt gtttgcagat tcctggctgt cgaagagaag cccgttctcc ttatcataga
    11821 taatgcgttt ttgttttacc agacttgtga tcagagattt gatagactct ctgtttttgg
    11881 aaaagagccg taagacctgt tcatattgca acgaatggta agttgtaatg aaccggagca
    11941 gttgggcacc ttccccttga tagatttcat ttcttgtttt catggtaatc tcccttcatt
    12001 atataatagg aagttttact tacactgtac gcacagaata cgttttattt taggggaagt
    12061 acgctgtacg tactgtgtaa gtattggcta ctgtcagcga aaggtttacg ggtacaaaaa
    12121 aagcaccgat taaggtgctg gggaaaatag gaatactata agcaatacct attgtaacat
    12181 gggtaaaatt acccttcaat cgcagaagtg tgccaagttg tggcatattt aggaaatgat
    12241 aaagacagtt gaaaaccaat taggaagaaa aaatgtcaat ctataccaaa aataaagacg
    12301 aaattcggag ataggatata ataaaaatca agatacttag gtatcaaaag gccctagttc
    12361 tgaagaaagg aatggtggat attatgagaa aatttgacag aacaaatatg aaatataaca
    12421 acccggctgg agatcttttg acagaattag aagcagcaga tttgacaagt aacaaagttg
    12481 atagtttagc ttcatcaggt gtggtttgca caatttctgt tgaatgcgga agtattttta
    12541 cacttgcttg ttgctaatta accaaagatg attttagaac tagggcctgg attaagagaa
    12601 agggagataa catgaaaaaa tctagttatt tatctgaaag agtgtatgat gctattccgt
    12661 ctgaaataaa tatggagtct ttagagtatt ggaagaaaat actgaaggag gaaggattac
    12721 aatatgtaaa gaaaaaccac cttgagtatt tttttggttt tataaataat tgtgctttta
    12781 gtagccacga gaagagtcaa ccacgaaatt ttgtgaaatt gtctttgaac aaaaaggcgt
    12841 ttaggcatga gggtgagaaa atggttttcg gagcatttta tgatcctttt gtgcaagagg
    12901 caaatagaca gcttagagaa atagttatac aaagacgata tatcaatgaa tcgattctat
    12961 ttgattttca gcaatttttg tttaattcgc ttaataatct ttgtatccga actttaattt
    13021 atgaaatgca tatatgtgga caa
//
