LOCUS       c00116_gnlPro..         4872 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PBIKMNCH_116.
ACCESSION   c00116_gnlPro..
VERSION     c00116_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 16:48:02
            Original ID  :: gnl|Prokka|PBIKMNCH_116
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4872
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4872
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[199:3143]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      200..3143
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..4872
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4872
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             200..1471
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_1"
                     /sec_met_domain="HGD-D (E-value: 1e-56, bitscore: 180.7,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWGAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLWPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERAFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGSA
                     LRRIETGIRHAKQAGADGAVWFGHWGCKHTLGAAQIAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
     CDS             1464..3143
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_2"
                     /sec_met_domain="HGD-D (E-value: 4e-18, bitscore: 53.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 2.8e-66, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPEGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKSHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADV"
     CDS             3647..4855
                     /locus_tag="ctg116_3"
                     /transl_table=11
                     /translation="MWEAINSFLTTVDNLVWGVPLMVLIMAGGILLTARLGLLQMRRLP
                     LALKWMFKNEEEGDGEISSFAALCTALSATIGTGNIVGVATAVCAGGPGALFWMILAAF
                     FGMATKFSEGLLAVKYRVVAEDGHSLGGPFYYIEKGMGTKWKWLAKIFAFFGVCVGLFG
                     IGTFSQVNGISSAVQNFFDPNKSNCVNIPFLGEYSWAVVISSLILAACVAAILIGGLKR
                     IATVSQIIVPFMAVIYLIFSVALILLNITEIPAAIVTVVKGAFNPSAVTGGVVGTMIVS
                     MQKGVARGIFSNEAGLGSAPIAAAAAQTKEPVRQGLVSMTGTFIDTIVICTMTGLSIVL
                     TGAWQVEGLEGVQVTTYAFQHGLPIPGQISAFVLMICLVFFAFTTILGWDYYSDDCFYR
                     CVY"
ORIGIN
        1 tgcggcaatg gaattttggc ttgtatgact cgggattttg gaatattcat gccaaaacac
       61 ctcgcagaat agtggtgtgt gaacagtaac gaaaattcaa cttgacttcc caaaaagata
      121 ttattaaaat attccgtggc actatttgtg cactgacaat tgataaatta ttattaccat
      181 aatgaggaag agacagacta tggagattat tgagacattt ggtcattatg tggaaaatct
      241 gacggataaa aagcctcagt cagcccgccg gctgttaaaa accggttggg gggcgcagaa
      301 tctgaagttc cgttacatgc aggacaagag actgatgcct gcagacaggc atcttgcaaa
      361 cctgatgatg gataccatgc tgtggcccct tcagaaaccg gaagattctg ttattgtaag
      421 tatttttaca ccctgcgaaa tgatgcagga ggtgggatta catccctata atgtagaagg
      481 attttcctgc tatctttctg caagcaaagc agagagggca tttttgcagc aggcagagaa
      541 tcagggaatt gcagagacac tgtgcagtta tcacaagaca tttcttggtg cagcgcagaa
      601 aggacttctg ccaaagccta aatgtattgt ttataccaac ctgacctgcg atgctaacct
      661 gctcaccttc cgtaccctgg cagattttta ccaggtacct gtatttgcca ttgatgtacc
      721 atggaatcag accacagaga atgtacagta tgtggcagat cagttaaagg atttaaaaat
      781 atttctggaa aaaaatacag gaaaaacaat ctctgaggac agattaaagg aacgtcttgc
      841 ctgcagtaag cggactctgg agaattacaa aaaatatcag cagatgcgtg cagacagata
      901 tgtgccctct gatctggtta cacccttgta tgcaggaatg acaaacaata tccttctggg
      961 aacagcagaa gaagagaagt atacacagat gcttcttgaa gatattaaga aagcaccggc
     1021 agcgaaaggg aaacacattt actggatgca taccattcca ttctggtcgg atgcagtgcg
     1081 ccaggagctt tgcttcagtg agaaagccca gatcgtagga tgtgaacttg cagaaacctg
     1141 tgagccggat tttgatcctg agaacccctt tgaagcaatg gcagaaagaa tggtatatca
     1201 ttcactgaac ggaagtgccc ttagaaggat tgaaaccggt atccgtcatg cgaaacaggc
     1261 aggagcagac ggtgctgtgt ggtttggaca ttggggatgt aaacatacgc ttggtgcggc
     1321 acagattgca aagaagaagt tcgaggaagc cggtctgccc cttttgatcc tggacggtga
     1381 cgggtgtgat cgaagccatg gaggagaagg acagacttcc accaggctgg gagcttttct
     1441 ggaaatgctg ggaggtgctg agaatgaata aaacttacta tgtctgtaaa tataccccaa
     1501 ttgaacttct ggaatctctt ggcggggaat gtgagaactt taatcatatg ccggagggat
     1561 ttgacctggc cgatcaggtt tcacatccca atatctgcgg ttttggaaaa acacttctgg
     1621 aaggagtcat ggaggggaaa atcaaggaac ttgtcctggt gagctgctgt gatactatcc
     1681 ggagtgtcta tgacattctg cttgaaagcg gcaagctgga ttttctctat attttggatg
     1741 tgcttcactg tgacagtgcc tgtagcagag agcgtatggc tgtacagtta aaagggctgg
     1801 cgaaggctta tgcacagtac aaaggcacag agtttgatgc cggaaaattc cgggctgctt
     1861 tccatgcaca ggagaaaatc acaaagtccc atattgcagt gcttggcgcc agaatggggc
     1921 aggaattatt tgaaatgacc agcaaagcta tgcctcttcc tgtagagaat gatacctgcg
     1981 tgcataaccg ttctgtggga aatatacttc caccggaggg tgcttctttt gatgagctga
     2041 tggactggta tgcaggtgag attctggggc agattccatg tatgcgtatg atggacccga
     2101 caggtcgtaa gaagctttat aatgatccgt ctgttgcggg gattatttat catacagtga
     2161 agttttgtga tttttacagc ttcgaatatg ctgagatcaa gaatcataca gatgtacctc
     2221 ttttaaaaat cgaatcagat tatactattc agagcagcgg tcagcttctt accagactgg
     2281 aagcttttgc agagagcatt cagcctgaaa cactggagca gaccatagat ggagacacaa
     2341 aaggagagag aaaaatggga aaaggttatt tcgcagggat tgacagtggt tctaccagta
     2401 cagatgtggt gattttaaat aaagatcatg agattgtgac cagcattatc ttgcctacag
     2461 gagcaggagc tgctatcgga gcagaccgtg cccttgcaga ggcattgaag gaggccggat
     2521 tgcagagaga agatattgat gcgctggtta ctactggata cggacgtaca gctattaaaa
     2581 atggtgataa gagtatcaca gagatcacct gtcatgcaag aggtgcgcat ttcctgaatc
     2641 cggaagtccg tactgttatt gatattggcg gacaggacag caaggtgatc cgactggatg
     2701 agaacggtgc agttgcaaat tttgttatga atgacaaatg tgcggcagga accggacgat
     2761 ttctggaaat gatggcacgt accatggaaa tgaatctgga tcagatgagc gaatgtgggc
     2821 tggaattcaa agaagatatt acaatttcca gtatgtgtac agtatttgca gaatcagaag
     2881 ttgtatccct gatcgcccag aataaggcaa cagatgatat tgtccatggc ctgaataagg
     2941 cggttgccgt aaagactgcc gcccttacca gacgtgtggg cggtgaggag aaatatatga
     3001 tgaccggtgg tgtttctaag aataagggcc tggtaaagac actggaagag aagcttggaa
     3061 caaagctggt gatcagtgac aaggctcagc tttgcggtgc acttggcgca gcactgtttg
     3121 cggctgatat ggctgatgta taaaaattat ttaaatatcc agggatttta caaggtggaa
     3181 atctctggaa tttttatact ttttttataa aagtttaatt ttctattgac gagttcaaat
     3241 ttaagagcta tagtatacca cagtaacagc aaattaacga ggtgaagttt gcaggaaaga
     3301 ggaagccaca caaaaggcta tacccgccga aggagtaaaa ctctcaggtt ccctggatgc
     3361 agggaagaac tgcaaatgga tcgtttctct ggagacaccc gttagatcgg gggccgaagg
     3421 tgcaaataac acgaattatc aatagctgcc cacaaatggt tatctgattc gtgtcttgaa
     3481 tctctcaggc aaaaggacag aggatgcttt atcatccccg ctgattcata tgaactatat
     3541 gaacagtatt ttctgaactt ctgatttttg aaacggtctg ttattacttt gtttcccagc
     3601 tgtacaatat attacacttt ttaaaagaaa aaggagattt attattatgt gggaagcgat
     3661 caattctttt ttgacaacag tagacaatct ggtctggggc gtgcccctta tggtcctgat
     3721 catggcaggt ggtatcctgt taactgccag acttggactt cttcagatgc gaagactccc
     3781 tcttgcattg aaatggatgt ttaagaacga agaagaaggc gatggtgaga tttccagctt
     3841 tgcagcttta tgtacagcac tgagcgccac aatcggaacc ggtaatatcg tcggtgttgc
     3901 aactgctgtc tgtgccggag gtcccggagc tttattctgg atgattctgg cagcattctt
     3961 cggaatggca acaaaatttt ccgaaggtct tcttgcagtg aaataccgtg tggtagcaga
     4021 agacggtcac agccttggtg gtcctttcta ttatattgag aaaggtatgg gaacaaaatg
     4081 gaaatggctt gcaaagatct ttgcattctt tggtgtatgt gtaggtcttt tcggaatcgg
     4141 tacattcagt caggtaaatg gtatttccag tgcagttcag aacttctttg atccgaacaa
     4201 atcaaactgc gtaaatattc cgttccttgg agagtattcc tgggcagttg taatttcttc
     4261 cctgattctt gcagcctgtg ttgcagcaat cctcatcggt ggtctgaaac gaattgcaac
     4321 agtcagccag attattgtac cgtttatggc ggtgatctat ctgatcttca gtgtagcgct
     4381 gattcttttg aacattacag agatcccggc agctatcgta acagttgtga agggagcctt
     4441 taatccgtca gcagtgacag gcggtgtggt aggaacaatg atcgtatcca tgcagaaagg
     4501 tgtggctcgt ggtatctttt caaatgaagc aggtcttggt agcgcaccta tcgcagcggc
     4561 agcagctcag acaaaagagc ctgtacgtca gggtcttgta agcatgactg gtacatttat
     4621 tgatacaatc gtgatctgta caatgacagg cctttccatc gtgctgacag gtgcatggca
     4681 ggtagaaggt ctggaaggtg ttcaggtaac aacctatgca ttccagcatg gacttccgat
     4741 ccctggacag atttctgcat ttgtattaat gatctgtctg gtattctttg catttactac
     4801 aattcttgga tgggattatt acagtgatga ttgtttttac aggtgtgttt attagccaca
     4861 tattctttac tg
//
