GCA_028325685.1 - 7 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaOJCAFAII_3 (original name was: gnl|Prokka|OJCAFAII_3)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	RiPP-like	1	8,389	quinolidomicin A	Polyketide	3%

gnlProkkaOJCAFAII_6 (original name was: gnl|Prokka|OJCAFAII_6)

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	T3PKS	1	27,622

gnlProkkaOJCAFAII_7 (original name was: gnl|Prokka|OJCAFAII_7)

Region	Type	From	To	Most similar known cluster		Similarity
Region 7.1	LAP,thiopeptide	1	23,101

gnlProkkaOJCAFAII_11 (original name was: gnl|Prokka|OJCAFAII_11)

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	RiPP-like	108,839	131,644
Region 11.2	RiPP-like	203,649	213,945

gnlProkkaOJCAFAII_18 (original name was: gnl|Prokka|OJCAFAII_18)

Region	Type	From	To	Most similar known cluster		Similarity
Region 18.1	NRPS	1	33,196

gnlProkkaOJCAFAII_19 (original name was: gnl|Prokka|OJCAFAII_19)

Region	Type	From	To	Most similar known cluster		Similarity
Region 19.1	lanthipeptide-class-i	1,758	27,771	nisin Q	RiPP:Lanthipeptide	81%

No secondary metabolite regions were found in these records:: gnlProkkaOJCAFAII_1 (original name was: gnl|Prokka|OJCAFAII_1); gnlProkkaOJCAFAII_2 (original name was: gnl|Prokka|OJCAFAII_2); gnlProkkaOJCAFAII_4 (original name was: gnl|Prokka|OJCAFAII_4); gnlProkkaOJCAFAII_5 (original name was: gnl|Prokka|OJCAFAII_5); gnlProkkaOJCAFAII_8 (original name was: gnl|Prokka|OJCAFAII_8); gnlProkkaOJCAFAII_9 (original name was: gnl|Prokka|OJCAFAII_9); gnlProkkaOJCAFAII_10 (original name was: gnl|Prokka|OJCAFAII_10); gnlProkkaOJCAFAII_12 (original name was: gnl|Prokka|OJCAFAII_12); gnlProkkaOJCAFAII_13 (original name was: gnl|Prokka|OJCAFAII_13); gnlProkkaOJCAFAII_14 (original name was: gnl|Prokka|OJCAFAII_14); gnlProkkaOJCAFAII_15 (original name was: gnl|Prokka|OJCAFAII_15); gnlProkkaOJCAFAII_16 (original name was: gnl|Prokka|OJCAFAII_16); gnlProkkaOJCAFAII_17 (original name was: gnl|Prokka|OJCAFAII_17); gnlProkkaOJCAFAII_20 (original name was: gnl|Prokka|OJCAFAII_20); gnlProkkaOJCAFAII_21 (original name was: gnl|Prokka|OJCAFAII_21); gnlProkkaOJCAFAII_22 (original name was: gnl|Prokka|OJCAFAII_22); gnlProkkaOJCAFAII_23 (original name was: gnl|Prokka|OJCAFAII_23); gnlProkkaOJCAFAII_24 (original name was: gnl|Prokka|OJCAFAII_24); gnlProkkaOJCAFAII_25 (original name was: gnl|Prokka|OJCAFAII_25); gnlProkkaOJCAFAII_26 (original name was: gnl|Prokka|OJCAFAII_26); gnlProkkaOJCAFAII_27 (original name was: gnl|Prokka|OJCAFAII_27); gnlProkkaOJCAFAII_28 (original name was: gnl|Prokka|OJCAFAII_28); gnlProkkaOJCAFAII_29 (original name was: gnl|Prokka|OJCAFAII_29); gnlProkkaOJCAFAII_30 (original name was: gnl|Prokka|OJCAFAII_30); gnlProkkaOJCAFAII_31 (original name was: gnl|Prokka|OJCAFAII_31); gnlProkkaOJCAFAII_32 (original name was: gnl|Prokka|OJCAFAII_32); gnlProkkaOJCAFAII_33 (original name was: gnl|Prokka|OJCAFAII_33); gnlProkkaOJCAFAII_34 (original name was: gnl|Prokka|OJCAFAII_34); gnlProkkaOJCAFAII_35 (original name was: gnl|Prokka|OJCAFAII_35); gnlProkkaOJCAFAII_36 (original name was: gnl|Prokka|OJCAFAII_36); gnlProkkaOJCAFAII_37 (original name was: gnl|Prokka|OJCAFAII_37); gnlProkkaOJCAFAII_38 (original name was: gnl|Prokka|OJCAFAII_38); gnlProkkaOJCAFAII_39 (original name was: gnl|Prokka|OJCAFAII_39); gnlProkkaOJCAFAII_40 (original name was: gnl|Prokka|OJCAFAII_40); gnlProkkaOJCAFAII_41 (original name was: gnl|Prokka|OJCAFAII_41); gnlProkkaOJCAFAII_42 (original name was: gnl|Prokka|OJCAFAII_42); gnlProkkaOJCAFAII_43 (original name was: gnl|Prokka|OJCAFAII_43); gnlProkkaOJCAFAII_44 (original name was: gnl|Prokka|OJCAFAII_44); gnlProkkaOJCAFAII_45 (original name was: gnl|Prokka|OJCAFAII_45); gnlProkkaOJCAFAII_46 (original name was: gnl|Prokka|OJCAFAII_46); gnlProkkaOJCAFAII_47 (original name was: gnl|Prokka|OJCAFAII_47); gnlProkkaOJCAFAII_48 (original name was: gnl|Prokka|OJCAFAII_48); gnlProkkaOJCAFAII_49 (original name was: gnl|Prokka|OJCAFAII_49); gnlProkkaOJCAFAII_50 (original name was: gnl|Prokka|OJCAFAII_50); gnlProkkaOJCAFAII_51 (original name was: gnl|Prokka|OJCAFAII_51); gnlProkkaOJCAFAII_52 (original name was: gnl|Prokka|OJCAFAII_52); gnlProkkaOJCAFAII_53 (original name was: gnl|Prokka|OJCAFAII_53); gnlProkkaOJCAFAII_54 (original name was: gnl|Prokka|OJCAFAII_54)

Compact view

gnlProkkaOJCAFAII_3 - Region 1 - RiPP-like

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Location: 1 - 8,389 nt. (total: 8,389 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

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core biosynthetic genes

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KnownClusterBlast

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaOJCAFAII_6 - Region 1 - T3PKS

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Location: 1 - 27,622 nt. (total: 27,622 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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core biosynthetic genes

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaOJCAFAII_7 - Region 1 - LAP,thiopeptide

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Location: 1 - 23,101 nt. (total: 23,101 nt) Show pHMM detection rules used

Region on contig edge.

LAP: ((((goadsporin_like or PF00881 or TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or TIGR03603 or TIGR03602) and not cyanobactin_synth)
thiopeptide: ((YcaO or TIGR03604) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

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core biosynthetic genes

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transport-related genes

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resistance

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KnownClusterBlast

Thiopeptides

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Thiopeptide predictions

No core peptides found.

Thiopeptides

Core peptide predictions

No core peptides found.

gnlProkkaOJCAFAII_11 - Region 1 - RiPP-like

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Location: 108,839 - 131,644 nt. (total: 22,806 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene overview

KnownClusterBlast

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaOJCAFAII_11 - Region 2 - RiPP-like

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Location: 203,649 - 213,945 nt. (total: 10,297 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene overview

KnownClusterBlast

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaOJCAFAII_18 - Region 1 - NRPS

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Location: 1 - 33,196 nt. (total: 33,196 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 33196:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - Cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg18_9

Search NORINE for peptide: strict or relaxed

AMP-binding (16..401): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GMVLMAVVVK
Nearest Stachelhaus code(s):: Boz GMVLRAVVVK (62% 8Å match)
Stachelhaus code match:: 90% (moderate)

AMP-binding (1068..1461): Cys

nrpys: Cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Small clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Single AA prediction:: Polar, uncharged (aliphatic with -SH) (Cys)

Stachelhaus prediction details:

Stachelhaus sequence:: DMFAIACNWK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

ctg18_10

AMP-binding (88..329): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GDGILLLTLK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

gnlProkkaOJCAFAII_19 - Region 1 - lanthipeptide-class-i

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Location: 1,758 - 27,771 nt. (total: 26,014 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03604))

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core biosynthetic genes

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Lanthipeptides

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		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Lanthipeptides

Core peptide predictions

No core peptides found.