LOCUS       c00480_gnlPro..        14745 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LFBPHJDJ_480.
ACCESSION   c00480_gnlPro..
VERSION     c00480_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 14:30:39
            Original ID  :: gnl|Prokka|LFBPHJDJ_480
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14745
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14745
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1305:4745]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1306..4745
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14745
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14745
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(93..1046)
                     /locus_tag="ctg480_1"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPAPGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             1306..1980
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg480_2"
                     /sec_met_domain="SucD_FumR (E-value: 1.2e-67, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             2019..3962
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg480_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 3e-60, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.9e-38,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             3990..4745
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg480_4"
                     /sec_met_domain="Fer2_3 (E-value: 1.2e-26, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3.6e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.8e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             4756..4941
                     /locus_tag="ctg480_5"
                     /transl_table=11
                     /translation="MYVYGKARRQWQRAFFMFVQTHKKAALPIIKVDAAFLLLSSETVS
                     RFPLCKDFVNLRSKIL"
     CDS             4938..5096
                     /locus_tag="ctg480_6"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(5069..6100)
                     /locus_tag="ctg480_7"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLDILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             6260..6616
                     /locus_tag="ctg480_8"
                     /transl_table=11
                     /translation="MVRLTSKEEEILGYFWAKGPLFVRELLDLQEESKPHYNTLSTIVR
                     SLEEKGYIGYKVYGNTHQYYALVSEDEYRRNSLKQVISKYYDNSYTRVVSTLIEEEVLT
                     IDELQKLIQQIKNK"
     CDS             6630..7262
                     /locus_tag="ctg480_9"
                     /transl_table=11
                     /translation="MDAFLLYILKSGICLTVFYVCFKALFSNDTFFRFNRWILLVGTGV
                     CMLLPLCRIQTARPFPLSRPVSQLEIVFYEEEMKAFPVPESKEEITIPTEQRNISVPWT
                     GIIGIAFLTGSGICLTTTILSFGKMYQLTRKNRKLKQGKYTLILTPDPVSPFSWGRYIF
                     LSENDYRNHPNEILMHEKMHLRYNHSVDLIYMKRFFFCNGLILPYGY"
     CDS             7430..8398
                     /locus_tag="ctg480_10"
                     /transl_table=11
                     /translation="MMLKKKSNNWARLKLALLVPVGFAALSAFARPETSPPPAATMTDN
                     IHLSINKSTVNQETMQQDHAVFLTYKESGSEDLNSIVCKTLDRIRTRVAEGQFKNALEV
                     TVNPAFDDIPASYLETVKDVLEERDIKCKIDMTVPNTIMDDVAKPYRKYDDVVYLIQNK
                     KIVAALSISKFSANQNDPRLDKISKSASLILQPENPKVSRQEMEKLKNLLDKKGLTSEI
                     NMNIFKIGDAAAPPPPPPAGQVIFSYRDGQPDQQFVLYDRHAKPGANLGQRIDKIYKDN
                     ITKVSIKINKSTPKDLLETVKQELKKKINYPVQYEILQFVD"
     CDS             8510..9745
                     /locus_tag="ctg480_11"
                     /transl_table=11
                     /translation="MIHNVKILFFICFFTACSSTEQKEIVTAGELLRQAAFYGERLQFL
                     PALETYQQAIKLAEKEKDSTVFSLAYLEMGKIYRYQSLKQKALQSEKKALSYIKSPACD
                     SLRLELYREIGDMYTLSGQADSAFHYYEMAGCRIKQAKILQQNGSNKEAETLLKTELEQ
                     TIFPKEKAEVCLALADLQITLGKLDEAEKSLSQVPPSHPHLYAALSRIAQSRGDSLQAD
                     FYHKSYLHHLSVLRQEKEQNQITQLLRTSEQKEWEKRLTDSQKAQKEQIYVWVTLLVSC
                     STGIWGYSRYRQKRNVVSLSETDFFSSEIYLRFHRKEEWKPVPKDWEELLQAFNRTYPD
                     FRERLKRKIPKLSEQEWRMCCLIKMEVPPSTAAMLLCCTNQAISMRRVRLYQKITGEKG
                     TPELCDSFIRDF"
     CDS             9812..11008
                     /locus_tag="ctg480_12"
                     /transl_table=11
                     /translation="MKKMLFGLMTAIATFTGCESKQPAGELPRIDLTATSFAFDQVEIA
                     DEIESIEYVPLELTDESLIADVLDLCVSDEYIFVYSTRQDGVLQFDRKGKYLRCIAKTG
                     NGPGETGQIISLTVDEENRLFCVSEYFSTSFYSFDGEFIKKIENPRPYSYQFSVGPNTM
                     AELGRMYVPMNTPGMFSLGVFNWGTDDTIAFRHTIGDMDLMPLEETSLKGWIFSGSKDG
                     ILCYSEGIDTVWDVNARNIAPAFLINTGYSVEEEKEMRSSKTGNEAVDGKYSVFSFFET
                     PRHYFVKCFEGSNQSKFYLYGLDKATGELKRETSPLNAQELFKNNWTLAGIGFRNTKDN
                     GLPIWPYLSYPGKKQMVQFNTAVEIEYLKEKYPDLKKHLVLQQITEDSNPLITIYHLR"
     CDS             11087..12322
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg480_13"
                     /sec_met_domain="Peptidase_U32 (E-value: 1.6e-69, bitscore:
                     223.7, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNNFTTDDLRK
                     IVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAMNYANSIGQ
                     EVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITGPKGELIRI
                     EMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIELDIENQYIM
                     SPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNGTFDEKKVA
                     AWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDKIGVAEFEM
                     ESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEKIRPSDRLY
                     KMEKVQLEKVFE"
     CDS             12322..12729
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg480_14"
                     /sec_met_domain="HBT (E-value: 1e-08, bitscore: 25.6,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 1.5e-09, bitscore: 28.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNAYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             12726..13841
                     /locus_tag="ctg480_15"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYF
                     KGNTNLDATRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRVGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAGATPVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVL
                     EIPVHQLSMLLFELEINGKVKALPGNLYKLS"
ORIGIN
        1 ttgttcatgt gacggctgac aatcgttaca agctctattt aaacggccgt tttgtctcac
       61 ttggacctgc acgtgggtgt tttagtagaa attcaatcac gttcgaaatc ggacagcact
      121 tctgccgtag tagcgttgat gttcttgtcc aatacataaa tgcggtaaga caggctcagt
      181 tctttaccgg gttccaatgt gaatgccttc tgcttggtcg gtgagaaatt ccacatgacg
      241 tcaccggcag gcttgttgac agttttgtcc catacgcgta agggctcagg atagtttagg
      301 ttggaagggg aggcaacgat taggatacag gccttttcgt ttccggcttt cccttggtag
      361 tagcaccaac gggctctcga accgtcagct tcgtcgcggg aaaggccttc cgaggtgagc
      421 atttcggctg tctgatcgtt ccagtcttcg cgcgtacgga tgcatatgcc gccataacgg
      481 taagcttcca tggtgatcgg gctggggctg gcgaggcgga tagtggtatg atagtcgatg
      541 taataacctg gtaaggatgt tgtcccgatg ttgatctcca ggcgttcgtt cattgctact
      601 ttttctgcgg gagaatcggg gtagaccaca tggtccagtg tcgcaacaaa accgttgtcg
      661 gatacgtgtt cgaagttgcg gaagcgaact gttccttgtt ttttgtggag attccagaaa
      721 tcgatctcgt ttccttcgaa cgtggttttc gtccaggcat accacaaacc gaaatgatgg
      781 taatggtcgg cgggagaaca attggtcatc acttcgcctc ccaatgtctt caaaggatgg
      841 atgaaaccgc tgcgtttata gaccgagtca acgccagggg ctgggtaaac cgtggtatag
      901 ttgtaagaga acaacagttt atctcctatc ttatagtcta aggttttccc cgtgtcgacg
      961 acggaacagg atgtttcgga aggctgacaa gagcctaaga acagagaaat caaaaaaaca
     1021 ccaatagaaa aaatagcagt tttcataata tgacaattaa ataataatca gttatccggc
     1081 aagaccttgc ctgtatcggc tacaaaaaaa cgaaattttt tcgtttcgca caatccgttt
     1141 gtgatatctg atgcaaataa aaccagccag caagcagcgt tctaattgat gaaatatttc
     1201 tttaatcgtt tgcgtgatat ggggatttag catacctttg cacgataata accatagatt
     1261 ggaggaaatt tctaaataca attaaataac ttaaattatt atcttatgtg gttacttaat
     1321 tcttctatcg ggaagaagct gataatgagt atatcaggtc tttttctcat tctgttcttg
     1381 gtgttccact tatgtatgaa cattgcggca gtattttctg gtgaagcgta taacgtgatt
     1441 tgcggtttgc tgggttctaa ctggtatgct ttgctcggta cattggtgtt ggctgcaggt
     1501 gtagtcgtgc acttcgtgta tgctattatc ttgactctgc agaatcgtaa ggctcgcggt
     1561 aacgaccgtt atgccatcaa cgctcgtccg aaaggtgttg aatgggcttc tcagaacatg
     1621 tttgttttgg gtgtgatcgt tatcctgttc atggttctgc actttactca gttctggtac
     1681 aacatgatgt ttgccgaact ggcaggtatt catggtgaca ttcatccgca ggatggtgca
     1741 gcgtttatca atttctactt ccagggcaat gttgtgaata cggtgttgta tctgatctgg
     1801 ttcgttgctc tgtggtttca cctgactcac ggtttctggt ctgcgattca cacaattggc
     1861 tggaacaata ccgtttggtt aagccgttgg gaatgtatct ctaaatgggt tgccactatt
     1921 atttgtggct tattcgctgt tatcacagtt atcttctacc tgaacggtgt aggtgcttaa
     1981 tttcggatat tattttttca atttgaaaat aaaacattat gactcaaata gattctaaaa
     2041 ttcctcaagg cccgttggct gagaagtgga caaattataa aaatcaccag aaattggtga
     2101 atcccgcaaa caaacgtcgt ttggacataa ttgtagtagg tactggtctg gcgggtgctt
     2161 ctgctgctgc ctctctggct gaaatgggat tcaatgtatt gaatttctgt attcaggact
     2221 ctccccgtcg tgcacactct atcgctgcac agggcggtat caatgcggca aagaattatc
     2281 agaatgatgg tgactcggtt tatcgtctgt tctacgatac aatcaaaggt ggtgactacc
     2341 gtgcccgcga agcaaacgtc tatcgtttgg ctgaagtgtc aaactctatt atcgaccagt
     2401 gcgtagcaca gggtgtacca ttcgctcgcg aatatggtgg tctgttggat aaccgctcat
     2461 tcgggggtgc tcaggtatcc cgtacgttct atgctcgtgg tcagaccgga cagcagctgc
     2521 tgttgggtgc ttactctgca ttgagtcgtc agattggttt gggaaaggtg aagatgtaca
     2581 cacgccatga aatgctggat gttgtgaagg ttgacggacg tgctcgcggt attattgccc
     2641 gtaatttgat taccggtaag atcgaacgtt ttgccgctca cgcagtcgtt gttgcgacag
     2701 gtggttatgt aaatacattc ttcttgtcta ctaacgcgat ggcgtctaac ggttctgctg
     2761 catggcagtg ctacaagaaa ggggcttact ttgctaatcc ttgtatggtg cagatccacc
     2821 cgacttgtgt gccggtgaaa ggtgacttcc agtctaagct gactttgatg tcagaatcac
     2881 tgcgtaacga cggccgtatc tgggttccga agaagctgga agatgcgaag gcattgcagg
     2941 ccggaacaaa aaagggaaag gatattcctg aagcagatcg cgactactat ctggaacgtc
     3001 gttatccggc attcggtaac ttggttcctc gtgacgtggc ttcacgtgcc gctaaagaac
     3061 gttgtgatgc cggtttcggt gtaaatagca cgggcttggc tgtattcctg gatttctccg
     3121 atgctatcaa ccgtctgggt aaggaagtgg ttaaacagaa atatggtaac ctgttcgata
     3181 tgtacgaaga gatcacgaac gatgatccgt acgaaactcc gatgatgatt tatcctgcat
     3241 tgcactactc aatgggtggt ttgtgggtag actatgaatt gatgacttct attccggggc
     3301 tgttcgcaat tggtgaagcc aacttctctg accacggcgc taaccgtctg ggtgcttctg
     3361 ctttgatgca gggattggcc gatggttact tcgtattgcc ttacacgatc cagaactatc
     3421 tgtctgacca gatccaggtt ccgcgcttta gcactgacct gcctgaattt gtggaagcag
     3481 aaaaggctat taacgcccgt atcgcgaagt tgatgaacgt gaagggtaaa gaaacagtcg
     3541 attctatcca ccgtaagctg ggacatatca tgtgggaaca cgtcggtatg gcacgcgacg
     3601 cggaaggctt gaaagaagct atccaaatgt tgaaagacct gaagaaggaa ttctggagca
     3661 atgtattcat tccgggtgag gccaatagct tgaacgtgga attggacaag gcattgcgtt
     3721 tggctgactt tatcgaaatc ggtgcgttga tggcacacga tgcgttagac cgtgcagaat
     3781 cttgtggtgg tcacttccgt acggaacatc agaccgaaga aggcgaagct atgcgtcatg
     3841 acgataagtt catgtacgtc tcttgttggg aataccaggg tgaagacaaa gacccggtta
     3901 tgctgaagga agatttgaac tatcagttcg ttgttcctca aacacgtaac tacaagaagt
     3961 aataatcatc aatcacaaaa attagaatca tggataaaga tataaaggta acacttaaag
     4021 tttggcgtca gaaaggtccg aaagataaag gacagtttga gacttaccaa atcgacaaaa
     4081 tcaatcagag tgtttctttc ttggaaatgt tagacatttt gaatgaacgt ttggttagcg
     4141 aaggcaaaga acctatcgta ttcgaccacg actgccgtga aggtatctgc ggtatgtgtt
     4201 cattgtatgt aaacggacat ccgcacggac cggcaacagg tgcaacaacc tgtcagctct
     4261 atatgcgccg tttcaatgat ggtgagacga ttacgatcga gccgtggcgt tctgctggtt
     4321 tcccggtaat ccgcgacttg atggtagacc gttatgctta tgataagatt atccaggcag
     4381 gtggtttcgt ttctgtaaac acaggtgggg ttcctgatgc taatgcaatt cctatttcta
     4441 aggctgatgc ggatttggct atggatgctg ctgcttgtat cggctgcggt gcttgtgctg
     4501 ctgcttgtaa gaacggttca gctatgctgt tcgtctctgc aaaggttagc cagctggctc
     4561 ttttgcctca gggtaaggtg gaagctgctc gtcgtgcaaa agcaatggtt gctaagatgg
     4621 atgaactggg ctttggtaac tgtacgaaca ctcgcgcttg cgaaatggaa tgtccgaaga
     4681 acatctccgt tagcaacatc gctcgcttga accgcgagtt catctctgct aagttacaag
     4741 actaatacat tatatatgta tgtatatgga aaagcccgtc gccaatggca acgggctttc
     4801 tttatgttcg ttcaaaccca caaaaaagcc gcactcccta taataaaagt ggatgcggct
     4861 tttttgttgc tttccagtga aacagtctct cgattccctc tctgcaaaga ctttgttaac
     4921 cttagatcta aaatactatg aaaaaaactc actgcaaata taaagtatat ttactgaata
     4981 cgcaagagtt tgtaattaca ttttattgca aatttgctac tttttgtttt aaaattgaca
     5041 ctgtgtgcgg attcacactg ttattatatc aacaatcgat cgattctgac acttgagagt
     5101 cgctttgaaa tccgtatcct gtatgaaatt tgtcggggat ggaatccaga atgtcgaata
     5161 atgcttccac tgtttccgca cgtagcatgg cgacgcgtgt ctgcttgaag tctgcaatac
     5221 ctttaaacag cggagttgca gccaaatggc ggcgaatgtg gagaattccc cggcgctcat
     5281 ccaaacgttc cacgctttgt tccacctgct ttttcagtat gtccagatac catgaaaaag
     5341 attcggcagg caatgtctcg cctgtatcca gataatgcct cacttctctg aaaatccagg
     5401 ggcggcctat gctgccccgg ccaatcataa cggcatccac gccatattgt tcgaaacgtt
     5461 gtttgcagat ttcggcggaa gtcacatcgc cattgccgat gatgggaatt tgtatacggg
     5521 gattgttttt tacttcaccg atcagtgtcc agtctgcctc tcctgtgtac atctgtgccc
     5581 gggtacgtcc gtggatggaa agggctgcga taccgcaatc ctgtagctgt tcggccaagt
     5641 ctacgatgat ccggttgtcg gcatcccagc ccaagcgggt ttttacggtg acagggatgt
     5701 tcaccgcttt gacgacttca cgggtgatgt ccagcatcag tggaatattg cgcagcatgc
     5761 cggcgcctgc tcctttgcct gccactcgtt tgacagggca accgaaattg atatcgagaa
     5821 tgtccggatg agcggcttcg caaatttgcg cggcttcgac cattgtcgga acatcacggc
     5881 catatatttg tatggcgacc ggacgttctt catccgccac attcagcttt tgctgtgttt
     5941 tatttacact gcggattagg gcgtctgctg aaacgaattc ggtataaacc atatcggcac
     6001 caaaacgttt gcacatcaac cggaaagaaa tatctgtaac gtcttccatc ggagctaaga
     6061 agacggggcg ttcgcctaaa tctattgtac ctattttcat atttatatta tcaatgacgg
     6121 ggacaaaggt actgatttcc tgctaaaaac agggataaaa ggatatctac taaaaaatat
     6181 agtaaaataa ctatatgata tagttgtgtt actaaataat atagttgtat ttgtgcattc
     6241 ctctaacaaa aaacggatta tggttagatt aacatcaaaa gaagaagaaa tattgggcta
     6301 cttttgggcg aaaggccccc tgttcgttcg cgaactactc gacttacagg aagaatctaa
     6361 gccgcattat aacaccttgt ccacgattgt ccgctcattg gaagaaaaag gatatatcgg
     6421 atacaaggta tacggtaata cgcaccaata ctatgcactg gtatcggaag acgaataccg
     6481 gcgtaattcc ttgaaacagg tgatcagcaa atattatgac aactcgtaca cccgtgtcgt
     6541 ttcgacgctg atagaagaag aggtgctcac gatcgacgag ttacagaagc tgatccagca
     6601 gataaaaaac aaataaaaaa ccaacgctta tggacgcttt tcttctatac atattaaaat
     6661 ctggtatttg cctgacagtc ttttatgtct gtttcaaggc attattcagt aacgacacgt
     6721 ttttccggtt caaccgctgg atattactgg tagggacagg agtttgcatg ttgctgccac
     6781 tttgccggat ccaaacagcc cggccttttc ctcttagccg gccagtcagc caactggaga
     6841 tagttttcta tgaagaagag atgaaagcgt ttcctgttcc ggaaagcaaa gaagaaatta
     6901 cgattccgac agagcagaga aatatatctg ttccctggac gggaattatc gggattgctt
     6961 ttctaacagg cagtggtatc tgcctgacca caacgattct gtcattcgga aaaatgtatc
     7021 aactaacaag aaaaaacagg aaactaaaac aggggaaata cacgttaatc ctgactcccg
     7081 atcccgtatc ccctttcagt tggggacgtt atatattcct ttcggaaaac gattaccgga
     7141 accatccgaa cgaaatcctc atgcacgaaa aaatgcacct ccgctataac cattcggtcg
     7201 atctgatcta tatgaaacga ttcttcttct gcaatggttt aatcctgccg tatggttatt
     7261 aaaaagggaa ttacggggca tacacgaata ccaggcggat aaaggcgtac tcagtcaagg
     7321 catcgatgca acaaaatatc aactattact cgtgaaaaaa gctgtcggct ccagcctcta
     7381 cactcttgcc aacagcttca atcacagtaa aattaaaaaa cgtattacta tgatgttaaa
     7441 aaagaaatca aacaattggg cccggttgaa gcttgcgctc ctggtcccgg taggcttcgc
     7501 ggccttaagt gcattcgccc gtccggaaac aagtccgccg ccggcagcga caatgaccga
     7561 caacattcat ctatcgatta acaaaagtac ggtaaatcag gaaacgatgc aacaggatca
     7621 tgcagttttc ctcacctaca aagaatcggg ttcggaggat ctgaacagta ttgtatgcaa
     7681 aactctggac agaatcagaa cacgagtagc ggagggacaa ttcaagaacg ccctggaagt
     7741 tactgttaat ccggccttcg acgatatccc ggcttcttat ctggaaacag taaaagatgt
     7801 tttggaagaa agagatatta aatgcaagat cgacatgact gttccgaata ctatcatgga
     7861 tgatgttgcc aaaccttacc gcaaatatga cgatgtggtt tatctgattc agaataaaaa
     7921 gattgtcgca gcactaagca tcagtaagtt tagtgcaaac cagaatgatc cgaggctgga
     7981 taagatatcc aaatcagctt ccttaattct ccaacctgaa aatccgaaag tatccagaca
     8041 agaaatggag aaattaaaaa acttgttgga caaaaaagga ttgacaagcg aaatcaacat
     8101 gaatattttc aagatcggag atgctgcggc tccacctccc ccacctcctg ccggacaggt
     8161 tattttcagt taccgggacg ggcagccgga ccaacagttc gttttatacg atcgccatgc
     8221 caaaccggga gccaatctcg gacaacgcat agacaagatt tacaaggaca atattacgaa
     8281 agtaagtata aagattaaca aaagtactcc caaagacctg ttggaaacgg ttaagcaaga
     8341 actgaaaaag aaaatcaatt accctgtcca atacgagatc ctgcaattcg tcgattaaaa
     8401 tcagaaacac ggattatcta tttatcatcc tctccgttta caaaacctgc tccagggggt
     8461 aaacggagag gaatattatt atctttactc cttcaaaaga aggattcaga tgatacacaa
     8521 tgtaaagata ctctttttca tttgcttttt caccgcctgt tcttctaccg aacaaaaaga
     8581 gattgtcacc gccggagagc tccttcgaca ggctgctttc tatggggaaa gattgcaatt
     8641 tcttccggca ttggaaacct atcaacaggc aatcaaattg gcggagaagg agaaagacag
     8701 caccgtcttt tcccttgcct acctggaaat gggaaaaatc tatcggtatc aatctttaaa
     8761 acaaaaggca ctacaaagtg agaaaaaagc attaagctat atcaaaagtc ctgcctgcga
     8821 ttcgctacgg ctggaacttt accgggaaat aggggatatg tataccttgt ccggacaagc
     8881 agacagtgcc tttcactatt atgaaatggc tggatgtcgg ataaaacagg caaagatatt
     8941 gcaacagaat ggaagcaata aagaggctga aactttatta aaaacggagt tggaacaaac
     9001 gattttcccg aaagagaaag cagaagtatg tctggctttg gctgatttgc agattacttt
     9061 gggaaaattg gacgaagccg aaaagagttt aagtcaggtc cccccttccc acccgcatct
     9121 gtatgctgcc ctgtcccgca tcgcccaaag ccgtggagac agcctgcaag ctgatttcta
     9181 ccacaaaagc tacctccatc acttatccgt cctgcgacag gaaaaagaac aaaatcaaat
     9241 tacccaactc cttcgtacct cggaacagaa agaatgggaa aaacgtttaa ccgatagcca
     9301 aaaggcacaa aaagaacaaa tatatgtctg ggtcacgcta cttgtctctt gcagtaccgg
     9361 aatctgggga tattcccgct accggcagaa aagaaatgtc gtttccctgt ccgaaacaga
     9421 tttcttttct tcagaaatct acctgcgctt ccaccgaaaa gaagaatgga aaccggttcc
     9481 caaagactgg gaagaattgt tgcaagcttt caaccggacc tatccggatt tccgggaacg
     9541 gctgaaaagg aaaataccaa agttgagcga acaggaatgg cgcatgtgct gcctgatcaa
     9601 aatggaagtt cccccttcta ctgccgccat gctcctttgc tgcacgaacc aggcgatttc
     9661 gatgcgccgc gtacgcctgt accagaaaat cacaggtgaa aagggcactc ctgagctgtg
     9721 tgattccttt attcgtgatt tttaagcaga tgtgaactga tgtgaaaccg gggaaatagc
     9781 cgtatcttct acttttgtct aaaaaaagcg tatgaaaaag atgttgttcg ggcttatgac
     9841 agccattgcc acttttaccg gatgcgaatc caaacaaccc gccggagaac tcccccggat
     9901 cgatctgaca gcaacaagtt ttgctttcga tcaagtagag attgcagacg aaatcgaatc
     9961 catcgaatat gttccgttgg aactaacgga tgaatccctg atcgcagacg tattggatct
    10021 gtgtgtttca gacgaatata tcttcgtcta ttctacccgt caggacggtg tcttgcagtt
    10081 cgaccggaaa gggaagtact tgcgctgcat cgctaaaaca ggaaacgggc cgggagaaac
    10141 cggacagatc atttcgctaa ccgtagacga agagaaccgc ctcttctgtg tcagcgaata
    10201 cttctccacc tctttctact cctttgatgg agaatttatc aaaaagatag agaatccgcg
    10261 cccttactcg taccaattct ctgttggccc gaatacgatg gcggaattag ggaggatgta
    10321 tgttcccatg aacacgccgg gcatgttcag tctcggagtc tttaattggg gcacagacga
    10381 tacgatcgca ttccggcata cgatcgggga tatggatctg atgccgttgg aagaaacgag
    10441 cctgaaaggt tggatattca gcggcagtaa ggacggcata ctatgctatt cggaagggat
    10501 agacacggtc tgggatgtaa atgcaagaaa tatcgctccg gcttttctta tcaacacggg
    10561 atattctgtc gaggaagaaa aagaaatgcg ctcttccaaa accggtaatg aggcggtaga
    10621 cgggaaatat agcgtcttca gcttctttga gacaccccgg cattacttcg ttaaatgttt
    10681 cgaaggttcc aaccaatcca aattctattt gtacggcttg gataaggcta ccggtgagtt
    10741 gaaacgtgaa acttctccgc ttaatgccca ggaattattc aaaaacaact ggacgctggc
    10801 aggaataggc ttccgaaata cgaaagacaa cggtcttcct atctggcctt acctgtctta
    10861 tcccggcaaa aaacaaatgg tacagtttaa tacagccgtg gaaatcgaat atctcaaaga
    10921 gaaatatcct gatctcaaga agcatctggt cctgcaacag ataacggaag attcaaatcc
    10981 gctcatcacg atttatcatt tgcgctgatc ttctcggata ttattcctac ctttgcgaac
    11041 gaaccagtaa atgtataaga acttgaacga gaaagatttt gaaataatgg cgcctgtcgg
    11101 ttcgtacgaa tcactgatgg cggctatcca agggggagcc gattctatct atttcggtat
    11161 cgaaggattg aatatgcgtt cgcgctcttc caataacttt acgacagacg atttgcgcaa
    11221 gatcgttgcg ctttgtcgtg agcacggtat taagagctat ttgaccgtca atacggttat
    11281 ttatggggaa gacctgcctc tgatgcgcga gattatcgat gcggcgaagg aggcggaagt
    11341 ttcagcgatc attgcggccg atgtggcagc tatgaactat gccaacagca tcggacagga
    11401 ggtgcatctt tccacacagc tcaacatttc caatgcggaa gcactgaaat tctatgcccg
    11461 ttttgctgat gttgtcgtct tggcgcgtga gctgaatttg aaacaggtgc atgaaatcta
    11521 tcggcagatc gtcgaccagc agattacggg accgaaagga gaactgatcc gtatcgaaat
    11581 gtttgcccac ggagctctct gtatggccgt ttccggtaaa tgttacctga gcctgcacga
    11641 aatgaacgct tccgccaacc ggggagcttg catgcagatt tgtcggcgtg cttattcggt
    11701 aaaagataaa gacagcaata tcgaactgga tatcgaaaac cagtatatta tgtcgcctaa
    11761 agaccttaag acaattcatt tcatgaataa gatgatggat gcaggtgtac gggtattcaa
    11821 gatcgaagga cgtgcccgcg gtcccgaata tgtccgcctg gtgaccgaat gctataagga
    11881 agctgtgcgt gcctattgca atggcacgtt cgatgaaaag aaagttgccg cttgggacga
    11941 acgcctgcgc agtgtgttca accgaggatt ctgggatggc tattatttgg ggcaacggtt
    12001 gggtgagtgg agtagcaaat atggctccgg cgcgactaag aagaaagtgt atgttgccaa
    12061 aggaatcaaa tatttcgaca agatcggcgt ggcggagttc gaaatggaat ccggtaacct
    12121 gaaagtgggt gatgagatcc tgattaccgg accgacaacg ggtgcggtta tgcagacgat
    12181 agaagaaatc cgtgtggact tgaagccggt ggacgagacc gttaaaggtg aacggttctc
    12241 tctcaaggtg aacgagaaga ttcggccgtc tgaccgattg tataaaatgg aaaaggttca
    12301 acttgaaaag gtatttgaat aatgaaagag tatattttta aactgacaga caaggtccgt
    12361 gactacgaat gcgacctgca aggagtggtc aacaactcca attatcagca ttatatggaa
    12421 catactcggc atgaattctt ggagtcgctt ggcgagaact tcggaaagat gcacgaaaaa
    12481 ggggttgacg gatttgtatc gcgggtagaa atccagtata agacctcgct caagagcggc
    12541 gacagctata tctcttgcct caatgcctat aaaaaaggag tcaagctcgt attcgagcag
    12601 gatatatata gggcttctga caatgcattg gcgacgaaag gaatcgtcga gtcggttatc
    12661 gttgagaacg gaaagttgac acgcggtgaa tatttcgacg aaatgctaaa aagaatagaa
    12721 catacatgac tgacaaacgg atttaccaaa tcggccttac tatgataaac ggcgtgggag
    12781 atatcctggc gcgtcatctc ctgcaggctt tgggagaagc agaggctgtg tttactgaaa
    12841 agcaacagtt gttaggaagg atccctggta tcggcagcaa tattgctgcc gaaatcaaac
    12901 gcccggaaat cttgcaacgg gcggaaaaag agttggcttt tatcgagaaa aacaatattt
    12961 cctgttatta tctgactgat acagattatc cggtgcgctt gagagaatgt ccggatgccc
    13021 ctatactttt ctattttaag ggaaatacta accttgatgc gacccgtatc atcagtattg
    13081 tgggtactcg caacgcgacc gaatatggtc gggagcttac cgaatccctt ataaaagact
    13141 tggcaaaagt gatcccggac ttgttggtcg tgagtggatt ggcttacggc atcgatatct
    13201 gtgctcaccg gaacgctttg tacaaccgac ttccgactgt tgctgtgctg gcgcatggct
    13261 tggatcgtat ctatccttcc tgccatcgga atacggctgt cgaaatgctg gaatcgggcg
    13321 gtctgttgac cgattttccc agcggtacag aaccagaccg tccaaatttc ctccggagga
    13381 accggattgt cgccggaatc tcggattgta cgatcgtggt tgaatcggca gaaaaaggag
    13441 gctctttggt aactgccgat attgcattct cttatggccg ggatgtctat agctttccag
    13501 ggcgtgtcgg tgacagccat tccaaaggat gcaacaattt gatccgacaa aataaagccg
    13561 gcctgatcac ttctgcggac gatctgctct ccgctctttg ttgggatatc caagctgggg
    13621 ctactcccgt tcaaacggag ttgtttttcg ccgaagcgga aacattcacc tcggaacaaa
    13681 atccggtttt agccattatg cgaacgcgga atgagattca tatcaacgag cttgcctcag
    13741 tgttggagat accggtacat caactctcta tgctattgtt cgaactggaa ataaacggga
    13801 aggtaaaagc gttgccggga aatctctata agctgtcctg accggctttt tcgtatacga
    13861 tttgtatgtg ggagaagaaa cggaacctct ataaacaatt aaaggctgtc tcacgacaac
    13921 ccctaaccaa ctttgttaac cttaaatcta atactattat gaaaaaacca cattgcaaag
    13981 atactctcgt caagagcgtt tgtcaagcat tttgttgcta atacttgtta atcagatgag
    14041 cataaatagc aaaaagattt taatcggcta taaagagtcc tttaaactgc gttattttgt
    14101 taaatcgagt ccttgaaaca ggtacggata gtccgtttcg atcacgtcgg gacgagtgct
    14161 gatctctgac cggtaaccgg cggttttctc tgtttccgtt ttcgcgcgat catgtgtcgg
    14221 agcaacggaa atcatgcaca tgactccgtt acggtgcaga gcgtcataca gtggttgctg
    14281 ttcaggcttc atcttcgggc ctacataagc cattacctgt ttccagggga tgccggcttt
    14341 ttcataatta tcgaattctt cccgattctt acaccagcaa gaaaacatcg catccggttt
    14401 ccggtcgaga taatagcggg cttgactggc gttatgtacc gtgtacatga cgttaacagg
    14461 cttttctgtt tctataaaat cagccataac ttctaaaggt acatccttga tatccaaatt
    14521 caggattgtt ttgcctttgc tccattccag gcattctttt aaagttggaa ttttgaaggc
    14581 tgtcacgttg ccgtttcggt ccaccagatt gaattgttgc agttctgcat aagtgtaatc
    14641 tgaaaccttt cctttcccgg tagttgtccg gtcgatggtt tcgtcgtgca tcaatacgat
    14701 tatcccgtct tttgtcaaac gcggatctat ctcgaaaaac gattc
//
