LOCUS       c00033_gnlPro..        15008 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PONIIKHG_33.
ACCESSION   c00033_gnlPro..
VERSION     c00033_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 18:12:05
            Original ID  :: gnl|Prokka|PONIIKHG_33
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15008
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15008
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1568:5008]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1569..5008
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15008
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15008
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(356..1309)
                     /locus_tag="ctg33_1"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPASGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             1569..2243
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_2"
                     /sec_met_domain="SucD_FumR (E-value: 2e-66, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             2282..4225
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.8e-59, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.1e-37,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             4253..5008
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_4"
                     /sec_met_domain="Fer2_3 (E-value: 2e-25, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 5.9e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.2e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             5199..5357
                     /locus_tag="ctg33_5"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(5330..6361)
                     /locus_tag="ctg33_6"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLNILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             6742..8001
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_7"
                     /sec_met_domain="Peptidase_U32 (E-value: 2.7e-68, bitscore:
                     223.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNN
                     FTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAM
                     NYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITG
                     PKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIEL
                     DIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNG
                     TFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDK
                     IGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEK
                     IRPSDRLYKMEKVQLEKVFE"
     CDS             8001..8408
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_8"
                     /sec_met_domain="HBT (E-value: 3.9e-08, bitscore: 27.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 6e-09, bitscore: 30.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             8405..9520
                     /locus_tag="ctg33_9"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYF
                     KGNTNLDATRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRIGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAGATSVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVL
                     EIPVHQLSMLLFELEINGKVKALPGNLYKLS"
     CDS             complement(9771..10667)
                     /locus_tag="ctg33_10"
                     /transl_table=11
                     /translation="MKMLSFILVLLLGGFMPAGNLLASDKEQNPHYITVKNSRDLQAYF
                     RYAPDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLMHDET
                     IDRTTTGKGKVSDYTYAELQQFNLVDRNGNVTAFKIPTLKECLEWSKGKTILNLDIKDV
                     PLEVMADFIETEKPVNVMYTVHNASQARYYLDRKPDAMFSCWCKNREEFDNYEKAGIPW
                     KQVMAYVGPKMKPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYRSEISTRPD
                     VIETDYPYLFQGLDLTK"
     CDS             11269..11631
                     /locus_tag="ctg33_11"
                     /transl_table=11
                     /translation="MERLTRQEEDVMRWIWQIEPCFIKDILAKYEEPKPPYTTLASIVK
                     NLERKKYVKAKRYGNTYEYRPLIPQEEYKRTFMGSVVNNYFENSYKEMVSFFAKEQKIS
                     TDELKEIIDMIEKGRE"
     CDS             11652..13388
                     /locus_tag="ctg33_12"
                     /transl_table=11
                     /translation="MTPEFAYFLKVNVAFILLYAFYRLFFYKDTFFKLRRTILLAFFGV
                     SLLYPLMNIQDWIREQGPIVEVIQMYSAILPETTITPGNVPQTNWHDLLLPGISYLYWS
                     GVIALSFRFLVQLSSILLLARRSEVTLIRNVRVHLLNKPAGPFSFFRLVFLHPDSHSEK
                     EIDEILVHECTHVSQWHSIDVIICELVCIICWVNPFVWLLKREVRHNLEYLADDTVLES
                     GYDSRSYQYHLLGLAHTNRSVTSLSNNFNMLHLKNRISMMNKKRSRSIGRTKYLIFIPV
                     VGALLILSNVDALARITDELTESTFADVLLPEAILPFPFVGDASPAEKREEYVLSEEGI
                     EAARRARNPVFTVVEVMPEFPGGQGALLKFLATNVRYPESAVKNGIEGRVSCSFVVGKD
                     GAISEAEVIRGVSPELNEEALRVINSMPVWSPGKQRGKVVNVKYTVPVTFRLSGGKKKT
                     SSRIVQRQIKEVDTSGRVFTVVQQMPEFPSGQASLLKYLATRIKYPAIAQENGIQGRVS
                     CSFVVDTDGSLKNIEVIRGIDPSLDREAVRVIREMPKWNPGVQNNMAVAVKYTVPVTFR
                     LQ"
     CDS             13422..14975
                     /locus_tag="ctg33_13"
                     /transl_table=11
                     /translation="MKCKFSLLLFLCVLSLWGQAQSLNLQELVNKKQFQEVVARADSLT
                     PADSADYATMSAIGQAYEGLLRYKEAYQCFSHCLKMDTNNVDALNAVARNAINFGRIAE
                     AKQCYRKVLGTDSMNFYANYQLARLYYQLGDYGRATEHYHILASIEGENPSILTGLADC
                     HIKRGTGPNTMIALSLYARALELNPENVRVASSLINTLLRMGDGQGALQVCDTALFYNP
                     DNSQIRQSKGMALYMTKDYKQADSVYTGLLADGDSSFLNLKYAGAARYMSGHALDGVEL
                     LEKAYEIDSTDVETVMLYGASLGKTYDRKRAYELFDLAETNMQPKKFLVNMLTTFRGDA
                     LERDGRWPEAEKLYYAAWKEDPTQLHFLYKISTQYWDVDPGLFQQEEKLQKTIFSRYTY
                     LTAYMKTDKSQKYLYNYRPFLEAVCEDAFFRNADEVTMLAPDGKKTKLAVADLRALVAQ
                     LPQMPEDERLRREKMQEHIKKAREKEKELRKSGAKLDTLALSKEEKEKARKMLKDADLE
                     "
ORIGIN
        1 ctcttttttc atctttgttg acttttatga agtcaaccta tttcaggacg agacaatcgc
       61 tcatctatct gttttaaatg aataaactcc aagcatttta aggtaaaagt agggagacaa
      121 ttttatcaac acccccatgt atccgccccc gacacccgga tcttacgctc ttatagatcc
      181 gggtgtcggg ggcggataca tgggggtgtt gggtaagttt tattacgtgt ttttcattga
      241 tttgtagctg tatttacata aaagagcctt gtctttgatg atataggaga acaagccctt
      301 tttccttttc ttgtttacct tgccctgcaa attgtcagtt tgttttagta gaaattcaat
      361 cacgttcgaa atcggacagc acttctgccg tagtagcgtt gatgttcttg tccaatacat
      421 aaatgcggta agacaggctc agttctttac cgggttccaa ggtgaatgcc ttctgcttgg
      481 tcggtgagaa attccacatg acgtcaccgg caggcttgtt gacagttttg tcccatacgc
      541 gtaaaggctc aggatagttc aggttggaag gggaggcaac gattaggata caggcctttt
      601 cgtttccggc tttcccttgg tagtagcacc aacgggctct cgaaccgtca gcttcgtcgc
      661 gggaaaggcc ttccgaggtg agcatttcgg ctgtctgatc gttccagtct tcgcgcgtac
      721 ggatgcatat gccgccataa cggtaagctt ccatggtgat cgggctgggg ctggcgaggc
      781 ggatagtggt atgatagtcg atgtaataac ctggtaagga tgttgtcccg atgttgatct
      841 ccaggcgttc gttcattgct actttttctg cgggagaatc ggggtagacc acatggtcca
      901 gtgtcgcaac aaaaccgttg tcggatacgt gttcgaagtt gcggaagcga actgttcctt
      961 gttttttgtg gagattccag aagtcgatct cgtttccttc gaacgtggtt ttcgtccagg
     1021 cataccacaa accgaaatga tggtaatggt cggcgggaga acaattggtc atcacttcgc
     1081 ctcccaatgt cttcaaagga tggatgaaac cgctgcgttt atagaccgag tcaacgccag
     1141 aggctgggta aactgtggta tagttgtaag agaacaacag tttatctcct atcttatagt
     1201 ctaaggtttt ccccgtgtcg acgacggaac aggatgtttc ggaaggctga caagagccta
     1261 agaacagaga aatcaaaaaa acaccaatag aaaaaatagc agttttcata atatgacaat
     1321 taaataataa tcagttatcc ggcaagacct tgcctgtatc ggctacaaaa aaacgaaatt
     1381 ttttcgtttc gcacaatccg tttgtgatat ctgatgcaaa taaaaccagc cagcaagcag
     1441 cgttctaatt gatgaaatat ttctttaatc gtttgcgtga tatggggatt tagcatacct
     1501 ttgcacgata ataaccatag attggaggaa atttctaaat acaattaaat aacttaaatt
     1561 attatcttat gtggttactt aattcttcta tcgggaagaa gctgataatg agtatatcag
     1621 gtctttttct cattctgttc ttggtgttcc acttatgtat gaacattgcg gcagtatttt
     1681 ctggtgaagc gtataacgtg atttgcggtt tgctgggttc taactggtat gctttgctcg
     1741 gtacattggt gttggctgca ggtgtagtcg tgcacttcgt gtatgctatt atcttgactc
     1801 tgcagaatcg taaggctcgc ggtaacgacc gttatgccat caacgctcgt ccgaaaggtg
     1861 ttgaatgggc ttctcagaac atgtttgttt tgggtgtgat cgttatcctg ttcatggttc
     1921 tgcactttac tcagttctgg tacaacatga tgtttgccga actggcaggt attcatggtg
     1981 acattcatcc gcaggatggt gcagcgttta tcaatttcta cttccagggc aatgtcgtga
     2041 atacggtgtt gtatctgatc tggttcgttg ctctgtggtt tcacctgact cacggtttct
     2101 ggtctgcgat tcacacaatt ggctggaaca ataccgtttg gttaagccgt tgggaatgta
     2161 tctctaaatg ggttgccact attatttgtg gcttattcgc tgttatcaca gttatcttct
     2221 acctgaacgg tgtaggtgct taatttcgga tattattttt tcaatttgaa aataaaacat
     2281 tatgactcaa atagattcta aaattcctca aggcccgttg gctgagaagt ggacaaatta
     2341 taaaaatcac cagaaattgg tgaatcccgc aaacaaacgt cgtttggaca taattgtagt
     2401 aggtactggt ctggcgggtg cttctgctgc tgcctctctg gctgaaatgg gattcaatgt
     2461 attgaatttc tgtattcagg actctccccg tcgtgcacac tctatcgctg cacagggcgg
     2521 tatcaatgcg gcaaagaatt atcagaatga tggtgactcg gtttatcgtc tgttctacga
     2581 tacaatcaaa ggtggtgact accgtgcccg cgaagcaaac gtctatcgtc tggctgaagt
     2641 gtcaaactct attatcgacc agtgcgtagc acagggtgta ccattcgctc gcgaatatgg
     2701 tggtctgttg gataaccgtt cattcggtgg tgctcaggta tcccgtacgt tctatgcccg
     2761 tggtcagacc ggacagcagc tgctgttggg tgcttactct gcattgagcc gtcagattgg
     2821 tttgggaaag gtgaagatgt acacacgcca tgaaatgctg gatgttgtga aggttgacgg
     2881 acgtgctcgc ggtattattg cccgtaattt gattaccggt aagatcgaac gttttgccgc
     2941 tcacgcagtc gttgttgcga caggtggtta tgtaaataca ttcttcttgt ctactaacgc
     3001 gatggcgtct aacggttctg ctgcatggca gtgctacaag aaaggggctt actttgctaa
     3061 tccttgtatg gtgcagatcc acccgacttg tgtgccggtg aaaggtgact tccagtctaa
     3121 actgactttg atgtctgaat cactgcgtaa cgatggtcgc atctgggttc cgaagaagct
     3181 ggaagatgcg aaggcattgc aggccggaac aaaaaaggga aaggatattc ctgaagcaga
     3241 tcgcgactac tatctggaac gtcgttatcc ggcattcggt aacttggttc ctcgtgatgt
     3301 ggcttcacgt gccgctaaag aacgttgtga tgccggtttc ggtgtaaata gcacgggctt
     3361 ggctgtattc ctggatttct ccgacgctat caaccgtctg ggtaaggaag tggttaaaca
     3421 gaaatatggt aacctgttcg atatgtacga agagatcacg aacgatgatc cgtacgaaac
     3481 tccgatgatg atttatcctg cattgcacta ctcaatgggt ggtttgtggg tagactatga
     3541 attgatgact tctattccgg ggctgttcgc aattggtgaa gccaacttct ctgaccatgg
     3601 cgctaaccgt ctgggtgctt ctgctttgat gcagggattg gctgatggtt actttgtatt
     3661 gccttacacg atccagaact atctgtctga ccagatccag gttccgcgct ttagcactga
     3721 cctgcctgaa tttgtggaag cagaaaaggc tattaacgcc cgtatcgcga agttgatgaa
     3781 cgtgaagggt aaagaaactg tcgattctat ccaccgtaag ctgggacata tcatgtggga
     3841 acacgtcggt atggcacgcg acgcggaagg cttgaaagaa gctatccaaa tgttgaaaga
     3901 cctgaagaag gaattctgga gcaatgtatt cattccgggt gaagcgaaca gcttgaacgt
     3961 ggaattggac aaggcattgc gtttggctga ctttatcgaa atcggtgcat tgatggcaca
     4021 cgatgcgtta gaccgcgcag aatcttgtgg tggccacttc cgtacggaac atcagaccga
     4081 agaaggcgaa gctatgcgtc atgacgataa gttcatgtac gtctcttgtt gggaatacca
     4141 gggtgaagac aaagacccgg ttatgctgaa ggaagatttg aactatcagt tcgttgttcc
     4201 tcaaacacgt aactacaaga agtaataatc atcaatcaca aaaattagaa tcatggataa
     4261 agatataaag gtaacactta aagtttggcg tcagaaaggt ccgaaagata aaggacagtt
     4321 tgagacttac caaatcgaca aaatcaatca gagtgtttct ttcttggaaa tgttagacat
     4381 tttgaatgaa cgtttggtta gcgaaggtaa agaacctatc gtattcgacc acgactgccg
     4441 tgaaggtatc tgcggtatgt gttcattgta tgtaaacgga catccgcacg gaccggcaac
     4501 aggtgcaaca acctgtcaac tctatatgcg ccgtttcaat gatggtgaga cgattacgat
     4561 cgagccgtgg cgttctgccg gtttcccggt aatccgcgac ttgatggtag accgttatgc
     4621 ttatgataag attatccagg caggtggttt cgtttctgta aacacaggtg gggttcctga
     4681 tgctaatgca attcctattt ctaaggctga tgcggatttg gctatggatg ctgctgcttg
     4741 tatcggctgc ggtgcttgtg ctgctgcttg taagaacggt tcagctatgc tgttcgtctc
     4801 tgcaaaggtt agccagctgg ctcttttgcc tcagggtaag gtggaagctg ctcgtcgtgc
     4861 aaaagcaatg gttgctaaga tggatgaact gggctttggt aactgtacga acactcgcgc
     4921 ttgcgaaatg gaatgtccga agaacatctc cgttagcaac atcgctcgct tgaaccgcga
     4981 gttcatctct gctaagttac aagactaata cattatatat atgtatatgg aaaagcccgt
     5041 cgtcaatggc aacgggcttt ctttatgttc gttcaaaccc acaaaaaagc cgcactccct
     5101 ataataaaag tggatgcggc ttttttgttg ctttccagtg aaacagtctc tcgattccct
     5161 ctctgcaaag actttgttaa ccttagatct aaaatactat gaaaaaaact cactgcaaat
     5221 ataaagtata tttactgaat acgcaagagt ttgtaattac attttattgc aaatttgcta
     5281 ctttttgttt taaaattgac actgtgtgcg gattcacact gttattatat caacaatcga
     5341 tcgattctga cacttgagag tcgctttgaa atccgtatcc tgtatgaaat ttgtcgggga
     5401 tggaatccag aatgtcgaat aatgcttcca ctgtttccgc acgtagcatg gcgacgcgtg
     5461 tctgcttgaa gtctgcaata cctttaaaca gcggagttgc agccaaatgg cggcgaatgt
     5521 ggagaattcc ccggcgctca tccaaacgtt ccacgctttg ttccacctgc tttttcagta
     5581 tgttcagata ccatgaaaaa gattcggcag gcaatgtctc gcctgtatcc agataatgcc
     5641 tcacttctct gaaaatccag gggcggccta tgctgccccg gccaatcata acggcatcca
     5701 cgccatattg ttcgaaacgt tgtttgcaga tttcggcgga agtcacatcg ccattgccga
     5761 tgatgggaat ttgtatgcgg ggattgtttt ttacttcacc gatcagtgtc cagtctgcct
     5821 ctcctgtata catctgtgcc cgggtacgtc cgtggatgga aagggctgcg ataccgcaat
     5881 cctgtagctg ttcggccaag tctacgatga tccggttgtc ggcatcccag cccaagcggg
     5941 tttttacggt gacagggatg ttcaccgctt tgacgacttc acgggtgatg tccagcatca
     6001 gtggaatatt gcgcagcatg ccggcgcctg ctcctttgcc tgccactcgt ttgacagggc
     6061 aaccgaaatt gatatcgaga atgtccggat gagcggcttc gcaaatttgc gcggcttcga
     6121 ccattgtcgg aacatcacgg ccatatattt gtatggcgac cggacgttct tcatccgcca
     6181 cattcagctt ttgctgtgtt ttatttacac tgcggatcag ggcgtctgct gaaacgaatt
     6241 cggtataaac catatcggca ccaaaacgtt tgcacatcaa ccggaaagaa atatctgtaa
     6301 cgtcttccat cggagctaag aagacggggc gttcgcctaa atctattgta cctattttca
     6361 tatttatatt atcaatgacg gggacaaagg tactgatttc ctgctaaaaa cagggataaa
     6421 aggatatcta ctaaaaagtg tagtaattga tcaatagaaa gtacaaatgt catactgtca
     6481 atgatataga taaaatgata agctgaaatc atgatagttg catgatagta gtatgatagt
     6541 taaaaataga aactatcatg tcttaaggta ttgaataaca gattctaaag gacaacaatg
     6601 acagtatgat ggttgttttg caaatcttta tagaaaatgg tatttgatca cgattttgat
     6661 gctctgagaa acggataccc atgcaattct tctcggatat tattcctacc tttgcgaacg
     6721 aaccagtaaa tgtataagaa cttgaacgag aaagattttg aaataatggc gcctgtcggt
     6781 tcgtacgaat cactgatggc ggctatccaa gggggagccg attctatcta tttcggtatc
     6841 gaaggattga atatgcgttc gcgctcttcc aataacttta cgacagacga tttgcgcaag
     6901 atcgttgcgc tttgtcgtga gcacggtatt aagagctatt tgaccgtcaa tacggttatt
     6961 tatggggaag acctgcctct gatgcgcgag attatcgatg cggcgaagga ggcggaagtt
     7021 tcagcgatca ttgcggccga tgtggcagct atgaactatg ccaacagcat cggacaggag
     7081 gtgcatcttt ccacacagct caacatttcc aatgcggaag cactgaaatt ctatgcccgt
     7141 tttgccgatg ttgtcgtctt ggcgcgtgag ctgaatttga aacaggtgca tgaaatctat
     7201 cggcagatcg tcgaccagca gattacggga ccgaaaggag aactgatccg tatcgaaatg
     7261 tttgcccacg gagctctctg tatggccgtt tccggtaaat gttacctgag cctgcacgaa
     7321 atgaacgctt ccgccaaccg gggagcttgc atgcagattt gtcggcgtgc ttattcggta
     7381 aaagataaag acagcaatat cgaactggat atcgaaaacc agtatattat gtcgcctaaa
     7441 gaccttaaga caattcattt catgaataag atgatggatg caggtgtacg ggtattcaag
     7501 atcgaaggac gtgcccgcgg tcccgaatat gtccgcctgg tgaccgaatg ctataaggaa
     7561 gctgtgcgtg cttattgcaa tggcacgttc gatgaaaaga aagttgccgc ttgggacgaa
     7621 cgcctgcgca gtgtgttcaa ccgaggattc tgggacggct attatttggg gcaacggttg
     7681 ggtgagtgga gtagcaaata tggctccggc gcgactaaga agaaagtgta tgttgccaaa
     7741 ggaatcaaat atttcgacaa gatcggcgtg gcggagttcg aaatggaatc cggtaacctg
     7801 aaagtgggtg atgagatcct gattaccgga ccgacaacgg gtgcggttat gcagacgata
     7861 gaagaaatcc gtgtggactt gaagccggtg gacgagaccg ttaaaggtga acggttctct
     7921 ctcaaggtga acgagaagat tcggccgtct gaccgattgt ataaaatgga aaaggttcaa
     7981 cttgaaaagg tatttgaata atgaaagagt atatttttaa actgacagac aaggtccgtg
     8041 actacgaatg cgacctgcaa ggagtggtca acaactccaa ttatcagcat tatatggaac
     8101 atactcggca tgaattcttg gagtcgcttg gcgagaactt cggaaagatg cacgaaaaag
     8161 gggttgacgg atttgtatcg cgggtagaaa tccagtataa gacctcgctc aagagcggcg
     8221 acagctatat ctcttgcctc aatgtctata aaaaaggagt caagctcgta ttcgagcagg
     8281 atatatatag ggcttctgac aatgcattgg cgacgaaagg aatcgtcgag tcggttatcg
     8341 ttgagaacgg aaagttgaca cgcggtgaat atttcgacga aatgctaaaa agaatagaac
     8401 atacatgact gacaaacgga tttaccaaat cggccttact atgataaacg gcgtgggaga
     8461 tatcctggcg cgtcatctcc tgcaggcttt gggagaagca gaggctgtgt ttactgaaaa
     8521 gcaacagttg ttaggaagga tccctggtat cggcagcaat attgctgccg aaatcaaacg
     8581 cccggaaatc ttgcaacggg cggaaaaaga gttggctttt atcgagaaaa acaatatttc
     8641 ctgttattat ctgactgata cagattatcc ggtgcgcttg agagaatgtc cggatgcccc
     8701 tatacttttc tattttaagg gaaatactaa ccttgatgcg acccgtatca tcagtattgt
     8761 gggtactcgc aacgcgaccg aatatggtcg ggagcttacc gaatccctta taaaagactt
     8821 ggcaaaagtg atcccggact tgttggtcgt gagtggattg gcttacggca tcgatatctg
     8881 tgcccaccgg aacgctttgt acaaccgact tccgactgtt gctgtgctgg cgcatggctt
     8941 ggatcgtatc tatccttcct gccatcggaa tacggctgtc gaaatgctgg aatcgggcgg
     9001 tctgttgacc gattttccca gcggtacaga accagaccgt ccaaatttcc tccggaggaa
     9061 ccggattgtc gccggaatct cggattgtac gatcgtggtt gaatcggcag aaaaaggagg
     9121 ctctttggta actgccgata ttgcattctc ttatggccgg gatgtctata gctttccagg
     9181 gcgcatcggt gacagccatt ccaaaggatg caacaatttg atccgacaaa ataaagccgg
     9241 cctgatcact tctgcggacg atctgctctc cgctctttgt tgggatatcc aagctggggc
     9301 tacttccgtt caaacggagt tgtttttcgc cgaggcggaa acattcacct cggaacaaaa
     9361 tccggtttta gccattatgc gaacgcggaa tgagatccat atcaacgagc ttgcctcagt
     9421 gttggagata ccggtacatc aactctctat gctattgttc gaactggaaa taaacgggaa
     9481 ggtaaaagcg ttgccgggaa atctctataa gctgtcctga ccggcttttt cgtatacgat
     9541 ttgtatgtgg gagaagaaac ggaacctcta taaacaatta aaggctgtct cacgacaacc
     9601 cctaaccaac tttgttaacc ttaaatctaa tactattatg aaaaaaccac attgcaaaga
     9661 tacactcgtc aagagcgttt gtcaagcatt ttgtcgctaa tacttgttaa tcagatgagc
     9721 ataaatagca aaaagatttt aatcggctat aaagagtcct ttaaactgcg ttattttgtt
     9781 aaatcgagtc cttgaaacag gtacggatag tccgtttcga tcacgtcggg acgagtgctg
     9841 atctctgacc ggtaaccggc ggttttctct gtttccgttt tcgcgcgatc atgtgtcgga
     9901 gcaacggaaa tcatgcacat gactccgtta cggtgcagag cgtcatacag tggttgctgt
     9961 tcaggcttca tcttcgggcc tacataagcc attacctgtt tccaggggat gccggctttt
    10021 tcataattat cgaattcttc ccgattctta caccagcaag aaaacatcgc atccggtttc
    10081 cggtcgagat aatagcgggc ttgactggcg ttatgtaccg tgtacatgac gttaacaggc
    10141 ttttctgttt ctataaaatc agccataact tctaaaggta catccttgat atccaaattc
    10201 aggattgttt tgcctttgct ccattccagg cattctttta aagttggaat tttgaaggct
    10261 gtcacgttgc cgtttcggtc caccagattg aattgttgca gttctgcata agtgtaatct
    10321 gaaacctttc ctttcccggt agttgtccgg tcgatggttt cgtcgtgcat caatacgatt
    10381 atcccgtctt ttgtcaaacg cggatctatc tcgaaaaacg attccatata ggacaaggtc
    10441 ttttcgaatg attcgatgca gttctccgga tagccgtcta gcattccacc acgatgtcca
    10501 ctgattacaa tcgggcgatc gggagcatac cggaaatagg cttgtagatc ccggctgttc
    10561 ttcacagtaa tgtaatgagg attttgttct ttgtctgaag ccaaaagatt cccggcaggc
    10621 ataaaacccc ctaaaaggag taccaaaata aaagatagca ttttcatgat attgtattta
    10681 tatagattct ttgtcaatta tgcggcttaa aagtaagact tttttatcag tggcgtacta
    10741 taaaagcact ataaaaacat gaaaatatga caggcaacaa gatgtgcaaa gaaagaggca
    10801 ggtatataaa aaattaagga ttgtcatctc gacaacccct aaccaacttt gttaacctta
    10861 aatctaatac tattatgaaa aaaccacaat gcaaaaatac actagctaag cttgtttgtc
    10921 aaacctttta cggataatat atgttaagct ctaatagcta ttttgtcaaa aaatgttggt
    10981 tatttataaa ctatacagat tccatgtaaa aactgctaat tcaaatactt tttatcgtcg
    11041 gaaaaagtga aatcccatgc ttaaaaagtg tccccttgga gtatataaaa tcattaatta
    11101 atatagggga tgctttggtg tggctgctta tagataaatt cctttttggc gcatgcagcg
    11161 aatagatgat agattattaa ttgttaatac aaattaacgc attatttctt gcacatttac
    11221 gatgtattcg tagatttgcg atacgatcgt aaaaaataat atagaaacat ggaaagatta
    11281 acaagacagg aagaggatgt aatgcgctgg atctggcaga tcgagccgtg ttttatcaaa
    11341 gacatcctgg cgaagtatga agagcctaag cctccttata cgacactcgc ttctattgtg
    11401 aagaatctgg aacgtaagaa atacgtgaaa gcgaaacgtt acggaaatac ttacgaatac
    11461 aggccgctga tcccacagga ggaatataaa cggacgttta tgggaagtgt ggtgaacaac
    11521 tatttcgaga actcttacaa ggaaatggtc tccttttttg ctaaagaaca gaagatatcg
    11581 accgatgagt tgaaagagat tatcgatatg attgaaaaag gacgagaata aactgttaaa
    11641 tacataatgc catgacaccg gaatttgcct acttcttgaa ggtaaatgta gcttttatac
    11701 tcctttatgc cttctaccgg ctgttctttt ataaggacac cttctttaaa ctacgccgta
    11761 ccatcttgtt ggcatttttc ggggtgtcat tgctttatcc gctgatgaat attcaggatt
    11821 ggatccggga gcaggggccg atagtggaag tcatacaaat gtattcagcc attttgcccg
    11881 aaacgacaat aacccccggc aatgttcccc aaacaaattg gcatgatttg ttacttcccg
    11941 gtatttctta tctttattgg agcggtgtaa ttgccttatc gttccgtttt ttagtgcagt
    12001 tgagcagcat cttgttactg gcacggcggt cggaagtgac tttgatccgt aacgtacgtg
    12061 tacatctgtt gaataaaccg gccggtcctt tttctttttt ccggctggta tttctgcatc
    12121 ccgacagcca ttccgagaaa gagatcgatg agattttggt acacgagtgt acgcatgtca
    12181 gccagtggca ttcgattgac gtgattattt gcgaattggt ttgtatcatc tgttgggtga
    12241 atccgtttgt ctggctgttg aaaagagagg tacgtcataa tctggaatat ttggcggatg
    12301 atacggtact tgaatcgggc tatgacagtc gtagctacca atatcacctt ttggggttgg
    12361 cacataccaa tagatcggtg acctctttat ctaataactt taatatgctg catctgaaaa
    12421 atcggatcag catgatgaat aagaaacgtt cccggagcat aggtaggacg aaatacttga
    12481 tttttatacc ggttgtgggc gccttgctga ttttaagcaa tgtcgatgca ttggcccgga
    12541 tcacggacga actgacggaa agcacgtttg ccgatgtctt gctaccggag gctatcttgc
    12601 cgttcccttt tgtcggtgat gcttctcctg ctgaaaaacg tgaggagtat gtgctatcgg
    12661 aggaaggtat tgaggctgcc agacgtgccc gtaacccggt gtttaccgtt gtggaggtaa
    12721 tgccggaatt ccctggcgga cagggtgctc tgctgaaatt cctggcgacg aatgtcagat
    12781 acccggaatc ggccgttaaa aatggtatag agggacgggt tagctgttct ttcgttgttg
    12841 gaaaagacgg ggctatctcg gaggcagaag tgattcgtgg ggtaagtccg gaactgaatg
    12901 aggaggcttt gcgtgtgata aactccatgc cggtatggtc gccggggaaa cagcggggca
    12961 aagtggttaa tgtcaaatat acggtaccgg taactttccg gctttccggt ggaaagaaaa
    13021 aaacatcctc tcgtatcgtg cagaggcaga ttaaagaagt cgatacgtcc ggtcgtgtct
    13081 ttacggtagt gcaacagatg ccggaatttc cgagtggaca ggcttcgttg ttgaaatatc
    13141 tggcaacacg cataaaatat ccggctattg ctcaggagaa tggaatacaa ggacgtgtct
    13201 cttgctcttt cgttgtcgac acggatggaa gtttgaaaaa tattgaagtg atccgtggaa
    13261 tcgatccttc gctggacagg gaggctgtcc gggtgatccg ggaaatgccg aaatggaatc
    13321 ctggcgtaca aaacaatatg gctgtagccg taaaatatac ggttccggtt actttccgtt
    13381 tgcagtaatt gaccagaatc ggtcattaat acgataccat tatgaaatgt aagttttctc
    13441 tattactgtt tctttgcgta ctgtcccttt ggggacaggc gcagagtctt aatcttcagg
    13501 aattggtcaa taaaaaacaa tttcaggaag ttgtagcacg tgcggatagt cttactcctg
    13561 ccgattcagc cgattatgct acaatgtcgg caatcgggca ggcgtatgag ggactgttgc
    13621 gctataagga ggcctatcag tgtttttctc attgcttgaa gatggatacg aacaatgtgg
    13681 atgcattgaa cgccgttgcc aggaatgcga tcaatttcgg aaggatagcg gaagctaaac
    13741 aatgttatcg taaagtattg ggaaccgaca gcatgaactt ctatgccaac tatcagttgg
    13801 cgcgtctcta ttatcagttg ggagattatg gtcgagcgac ggaacactat catatacttg
    13861 cttccatcga aggtgaaaat ccttctatcc tgaccgggct ggctgattgc catattaaaa
    13921 gagggaccgg tcctaatacg atgatcgctc tttctttgta tgcccgtgct ttggagctga
    13981 acccggaaaa tgtacgtgtg gcatcttctc tgataaatac gttattgcgg atgggggacg
    14041 gacagggagc tttgcaggtg tgcgataccg ccttgttcta taatccggat aacagccaga
    14101 tacggcagag taaagggatg gctctctata tgacgaaaga ttataagcag gccgattcag
    14161 tctataccgg tctattggcc gatggcgatt cttctttttt gaatcttaaa tatgcggggg
    14221 cggcccgcta tatgtccggt catgcacttg atggggtcga gctgctggag aaggcctatg
    14281 aaatagattc gacggatgtg gaaacagtca tgttgtatgg cgcttccctg ggaaaaacat
    14341 acgaccgtaa acgggcttat gagcttttcg atctggcgga aacgaatatg cagccgaaaa
    14401 aattcctagt taatatgttg acgaccttcc gaggtgatgc cttggaaagg gacggccgtt
    14461 ggcccgaagc ggaaaagctg tattatgccg catggaagga agacccaacc cagttgcact
    14521 tcctgtataa gatcagtaca caatactggg atgtcgatcc gggactcttt cagcaggagg
    14581 aaaaattgca aaagacgatt ttcagtagat acacttacct gacagcctat atgaagacag
    14641 acaagtcgca aaagtatctt tataattacc gccctttctt ggaagcggtt tgtgaagatg
    14701 cctttttccg gaatgccgat gaagtgacga tgttggctcc cgatgggaag aagacgaagt
    14761 tggctgtcgc tgatctgcgt gccttggtcg cccaactgcc gcagatgccg gaagatgaac
    14821 gtttgaggcg cgagaagatg caggaacata ttaaaaaagc cagggaaaaa gaaaaggaat
    14881 tgcgtaaaag cggtgctaaa ctcgatacgc tcgccctgag taaggaagaa aaagagaaag
    14941 cacggaaaat gttgaaagac gccgacttgg aatagataga atatctgaac aatataatcg
    15001 atataaat
//
