LOCUS       c00161_gnlPro..        17095 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PBFEAGBH_161.
ACCESSION   c00161_gnlPro..
VERSION     c00161_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 18:42:57
            Original ID  :: gnl|Prokka|PBFEAGBH_161
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17095
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..120
                     /locus_tag="ctg161_1"
                     /transl_table=11
                     /translation="YINNLKEESETIIFERTFMLFELSDEFRYRILLPPTRQG"
     protocluster    1..17095
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4568:7095]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4569..7095
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17095
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17095
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             74..886
                     /locus_tag="ctg161_2"
                     /transl_table=11
                     /translation="MNSDTGFSCHQLDKDDVYQIDNSKSSCALFVIQGRVNFDLGKSYE
                     GEMEQRQMLYIPQNMKAQIESITSSRCILLFWDKHLNVCNKLFLNSLLSKENDTDIKNI
                     ILPIKSPLMNILESINLYLDARLLCRHMHSLKQQELLLVLRGFYTKQELAAFFSASTNI
                     GESFERFVLDNYKRTNSIKELANLCHISERSFNRKFHSCFGESPYKWIQKKKAEQIQEM
                     INDPEFSFKEIAEELGFSSSPHLTTYCQRMFGMTPSQLREKNKDKWIK"
     CDS             897..1568
                     /locus_tag="ctg161_3"
                     /transl_table=11
                     /translation="MEKSEELQIATSGKNMDIHRMELLPVVCLSVYKEIIKEMAELIED
                     KQIREIFCSLSLGKDLLCVSQITGISSKNLVSMYKRGIRQIHLKWKPYSELKRELDHIY
                     IKYRNNELLLTHSEEVSKKNFRYVKIVLKEQDIPTEYVDLLSTPLSKLDINSRTLRAFR
                     KYNIYQLEDLLRFIKYNGFEALYQMPGIGTKSIEQLYEKLKDKKILVDQDTCFLFPYLF
                     V"
     CDS             complement(1849..3414)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg161_4"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1e-47, bitscore:
                     153.8, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSAMKDQLSGIFSGLVSQYVFDIQVAPDHESRQELIDLLGDVA
                     SCSDHLSCSVADGEGLQFTIVKDGMPTGIRFRAVPNGHEFTSLLLAVLNCDGKGKNIPD
                     EGICARVRALNGPIKLTTYVSLTCTNCPDVVQALNVMATLNSCITHETVDGAINQKEVE
                     AMKVQGVPSVFADGRLINVGRSDLGELLSKLEAQYGINEGGVDNSVEKPVKNYDVLIVG
                     GGPAGAASAIYSARKGLNVAVIAERIGGQVKETVGIENLISVPQTTGQQLANDLLTHIN
                     DYPVDILEHRCVDKVELDGSTKLLTTSTGERFSAPALIVATGASWRKLNVPGEADYIGK
                     GVAFCPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADQVLQEK
                     AKSLPNVEVFLHSQSLEVLGNGDKVTGLRVKDRKTDAERVIDLDGIFVQIGLAANSGVF
                     RDVVETNKPGEIVIDAHCRTNVPGIYAAGDVSTVPYKQIIIAMGEGAKAALSAFEDRMR
                     GLIG"
     CDS             complement(3419..3985)
                     /locus_tag="ctg161_5"
                     /transl_table=11
                     /translation="MEPIINSQVPEFKVQAFQNGSFKTVSSEDIKGKWAIFFFYPADFT
                     FVCPTELVDMADKYGKFQEMGVEVYSVSTDSHFVHKAWHDASETIRKIKYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKIAEIHDNGIGRNADELLRKVEAAQFVASHP
                     NEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             4441..4566
                     /locus_tag="ctg161_6"
                     /transl_table=11
                     /translation="MGHYIYFTNCEGDVTSIESDSVRTVNRISRKPVTIREQTLD"
     CDS             complement(4569..5300)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 73.4;
                     E-value: 7.5e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg161_7"
                     /sec_met_domain="Radical_SAM (E-value: 1.9e-35, bitscore:
                     113.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LINMLGRIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWE
                     VKRETPYLLEPEALLAEVLRYKNFIAKGGVTVTGGEPLLQPEFLKEFFRLCRENGIHTA
                     LDTSGYICSGKALEVLEYVDLVLLDIKTIDAGLHPRLTAVKLDNTLRFLDELEKRGIPV
                     WVRHVVVPGLTDNDEDLEKLAGYVSRYKVVQKAELLPYHTMGAYKYEAQGLDYKLKGVE
                     PLSAERLTNAKAIFSKHGITV"
     CDS             complement(5308..7095)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg161_8"
                     /sec_met_domain="Gly_radical (E-value: 1.6e-45, bitscore:
                     145.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 4.5e-221, bitscore:
                     726.4, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAARRSAIITGLPDAYGRGRIIGDYRRVPLYGTQILIEEKKRFQ
                     KRLDIQELTEEIIQSREEITEQIKALKAFEKMCAGYGFDVTRPAKDAREAVQFLYLAYL
                     AAVKDQDGAAMSLGRTSTFLDIYIEKDICEGKLTEEEAQELIDQFIIKLRIVRFLRTPE
                     YNDLFSGDPVWVTESLGGQGVDGRSLVTKTSYRYLHTLYNLGPAPEPNLTVLWFNNAPD
                     NWKNFCAKVSIDTSAIQYENDDLMRPDYGDDYGIACCVSPMKIGKQMQYFGARANLAKC
                     LLYAINGGRDEKSGVQVAPRFEPITSEYLDYNEVMEKYEQMMRWLAKVYVNALKIIHYM
                     HDKYAYEAFEMGLHDGDVERIRATGIAGLSIVADSLAAIRDTKVKVIRDERGLAVDFER
                     EGEYVPFGNNDDRTDSIAVDITEKFMEYLRQHQTYRKATPTQSILTITSNVVYGKKTGT
                     TPDGRPGGTPFAPGANPMNGRDTKGAVAALASVAKLPFQHAHDGISYTFAVSPATLGKE
                     RDIQVNNLVSLLDGYFTPDGGQHLNVNVFDKDLLLDAMEHPEKYPQLTIRVSGYAVNFV
                     KLTREQQLDVISRTINSSL"
     CDS             7177..7389
                     /locus_tag="ctg161_9"
                     /transl_table=11
                     /translation="MIAIGFQTVFDHADTAFREDTAFQRGVCLQADDYFVFLIDVTGSV
                     CVNPLGKLRFGIIYSFLPFNLKHLG"
     CDS             7514..7780
                     /locus_tag="ctg161_10"
                     /transl_table=11
                     /translation="LNCAQFSFSNFISLSCLFRFRHAKIRLFPLSEKDCKGRGMLNRRK
                     YLQIGIREIKTKPRQYEYRRGLFFVCRPVFTEGKAVELLISLL"
     CDS             complement(7975..10515)
                     /locus_tag="ctg161_11"
                     /transl_table=11
                     /translation="VTVANALALAQTNNVVKVDETGTALILCKYTAEQNADIAKMNDTM
                     GGEGFNLTSAGDKFEGNIFKNGDEYLNLKAFEVVTGTIANVPAGTYFVVVDENMPATLK
                     GKDAQLDKKEEFEAATFVAVDPLKNLNINEVPRGKGKGFWFTKVKGSDFHFNNVAGEVS
                     KKDEIYVGNACFTVINPTLLDETTYQIYTNNARVLKEEGKDDHIAAGKQFIGFVKDQDV
                     DYMITNDEDHALTFKATNETLYDVKGLLNDTDAPAIYTIQFVSGEDKEGVSEYGQWLTV
                     DQHATQSGLRLASVEEINEQDPRFQFVVKKISDYNTDTKKYKKVTFANRQSGVEIELSL
                     FKEGDAYIVYTTDNSNNWDVYPEYIDGNDVNGDVTFGNGVKWATTKIALNPVTVEDKFA
                     SFVNREEGAGLVTFALAKNDEAAPEFYVGAKRNAKGLMTGEIFSYSDALDAAQFELEKS
                     EKFLTALNTYMYVKNGRPITSTEKDTVAFYTYKVKAFDADQDNMYLKWGSNNFDLGATG
                     LNFVIKENIDGSVSLIDYNTTNKLEGNSLKVADKLKDGKTAPWATASAYDLTTLLSEGL
                     KTYMVEESPLVSLEAVPQHISFEAVRGGFMTMDENKDARLAIANEASEDLTFWVDTVHS
                     NLNIPSFYITKGGNFLYNAVDSASYYAARKNYRFNLENKATGDAKLIFKAGELVSSDTL
                     RTIVDGKSVLVAEKDNAPKKIKGGLKNFQFQIVRAEEGSDEYVIRKDGQYVCQYNNYFY
                     MKADKSEAYRFVIEKQSAPTANEGIATSEVKVIAGEGNVTIAGAAGKKVVISNILGQVV
                     ANTVISSDNATIAAPAGVVVVAVEGEAAVKAIVK"
     CDS             10712..11029
                     /locus_tag="ctg161_12"
                     /transl_table=11
                     /translation="VYDFVPAAFVSSFTVNFQTASANFAVESSSALVVNTLPFKVAVKA
                     KSSLLIPSFVKSRRIMYSPEVTLSFSNVTGSKLLGKICAEANALVSRNPAIRVENFLFI
                     I"
     CDS             complement(11690..12142)
                     /locus_tag="ctg161_13"
                     /transl_table=11
                     /translation="VNLPVVCLEVGIELSGIVDTALFQYVQHAFLFVRRERAFAFSHAV
                     VSPASEPSHQLANGFLHQFVGHPVQHPDETERIGQFIGRAEISTSVGLLLLVFRADDVP
                     QFDFVADLLFCDSPQASSGFGAILFHAEQIGGGDVGRVDFFFHILY"
     CDS             12143..12274
                     /locus_tag="ctg161_14"
                     /transl_table=11
                     /translation="MTQLAYVLVVPYLCNDRFLGMKRLCQAYVTGVSYSGNSCAKPM"
     CDS             complement(12758..13021)
                     /locus_tag="ctg161_15"
                     /transl_table=11
                     /translation="LGIEFVIEGQDKTGYGDRIAMVFLASVVRTPETVDAVVHKVCEDL
                     PISAEAELVISVGINVCGLFHCGFFCRCFFLFLCKCRYTRGE"
     CDS             complement(13028..13303)
                     /locus_tag="ctg161_16"
                     /transl_table=11
                     /translation="VPGRRKDGRFAFRTRSSEEVDRLVMLVGQTDRDDQMTGTDIEGRM
                     DKTCDVELFQSNFTAFFNFHFVFSVFCVFYLIGTSRTSSLKFYFCS"
     CDS             complement(13490..13888)
                     /locus_tag="ctg161_17"
                     /transl_table=11
                     /translation="VLAFAFFLWVVVFVADERIDYGYAHIVFTNRTQVEPHFTTVADRT
                     FGDRGCLCIRRTAALVVVDTAEVVGFAQVAVYHVCACGDIFVFVLQVSRIDAQRYVSIF
                     DVCFRFVGIGSRIVAIVEGTAYFQSRYS"
     CDS             14102..15367
                     /locus_tag="ctg161_18"
                     /transl_table=11
                     /translation="MKKKNYFYLAALSLAMTFSMGACSDNNDPNPDGGGKDPVNLDYSS
                     ENASAWGNYMYNVAMLLNDDATMLYNSWVTDYVDEQGSHGPYATIFKDQTAGAYQSPLS
                     CIEEMIESGMWNIANEVGDAKIKDPYTKYTSGDKEGGLYAVESWYSWHSRDDYTNNIFS
                     IRNTYYGRIDDNDVSKVDGNLSAFNSYKDFDDEGDIAEHSLSKLIASTNPALDEEIKTL
                     IFASAKAIQAIPQPFRNNIDSEESVAAMNTCMELANLLLNEVKPYVNQTFGDPEYDDDL
                     DAIAEQFVDAVVLPTYKDLQEKNKLLLDAVNQFRQNPSNDNFEKACNLWITAREPWEKS
                     EAFLIGPVANLGLDPNMDSWPLDQNGIVQVLNSQNWDDLEWSGNFDEEDEAIGAAQSVR
                     GYHTLEYLLFKDGQPRTVDGAK"
     CDS             complement(15458..15664)
                     /locus_tag="ctg161_19"
                     /transl_table=11
                     /translation="MSLGKSLKSLLTAHIRSGHLFYPYPFYRPLHKLRMQRAGIARMLT
                     GKIASYHFIGFLNLFPNNASRIV"
     CDS             complement(15661..15822)
                     /locus_tag="ctg161_20"
                     /transl_table=11
                     /translation="MATAAGIAGINRSETASVAIVAGAYIVVETVAVVETDRVGSCYPV
                     GVRIVGDR"
     CDS             15892..16947
                     /locus_tag="ctg161_21"
                     /transl_table=11
                     /translation="MLVYISRRNGAFFRDYGRVLHDQAIYGVKPEGKLSVTYDKQTFSF
                     PDGETYELCKPNYTITEWYKDSIAPEDLFCTVRIPLRHVGMGQMMAIDRREIEALAAKS
                     NYPEYGISGRCNYITEKGVTGVGLSGNKAQHLDLTVELGFSSDMGVTNSRYPEEICEGQ
                     AQINQGSMMGLSYDQLDISTADMEDVDLYMQSLGVPARRNINDPQVILGEQKFYEAKCH
                     LCHVTTLHTQAGGSTLLNGTRLPWLGGQTIHPYSDFLLHDMGSEIMGVGLNDNYVSGLA
                     RGNEWRTTPLWGIGLQEKVNGHTYFLHDGRARNLTEAIMWHGGEGEASKNLFKQMSKEE
                     REAVIAFLNSL"
ORIGIN
        1 tatataaaca atttgaaaga agaaagtgaa actattatat ttgagagaac atttatgttg
       61 ttcgaattat cagatgaatt cagataccgg attctcttgc caccaactag acaaggatga
      121 tgtataccag attgacaaca gcaagtcatc ctgtgcgctc tttgtgattc aaggccgggt
      181 gaatttcgat ttagggaaat cttatgaggg ggaaatggag cagagacaga tgttatacat
      241 acctcagaat atgaaagccc agatagaatc cataacaagt tcaagatgta ttcttttgtt
      301 ttgggataag cacttgaatg tatgtaataa gttgttttta aactctttgc tttctaaaga
      361 gaatgataca gatataaaaa atattattct tccgatcaaa agtccattaa tgaatatatt
      421 agagtccatt aacttgtatc tggatgcaag attactttgt aggcatatgc attcactgaa
      481 acagcaggaa ctgctcctag tcttgagagg tttttacaca aagcaagaac tggcagcttt
      541 tttttccgca tcaaccaata tcggggaatc atttgaaaga tttgtcttgg ataattacaa
      601 aagaacaaat tcaatcaagg aacttgctaa cttatgccat atatcagaac gatctttcaa
      661 ccggaagttt cattcttgtt ttggggaaag cccttataaa tggatccaga agaaaaaagc
      721 ggaacaaata caggagatga ttaatgatcc ggaattttct tttaaggaaa tagccgaaga
      781 actgggcttc agttcttcgc cacatctaac aacatattgt caaaggatgt ttgggatgac
      841 ccccagccaa ttaagagaaa aaaataaaga taaatggatt aaataaattg ttttttatgg
      901 aaaaatcgga agagcttcaa atagcaactt caggaaagaa tatggatata caccgtatgg
      961 agctattgcc tgtggtatgc ttatcggttt acaaagagat tataaaagaa atggcagaat
     1021 tgattgagga caaacagata cgggaaatat tttgttcact atctttagga aaagatcttc
     1081 tatgtgtttc acagataaca ggcatttcgt ccaagaatct ggtttccatg tataaaaggg
     1141 ggatccgaca gatccatttg aagtggaaac cttattcaga attaaaacga gaactagatc
     1201 acatatatat caaataccga aataatgaat tgcttttgac acattctgaa gaggtttcaa
     1261 aaaagaattt caggtatgta aagattgttt tgaaagagca ggatattcca acggaatatg
     1321 tggatctatt aagtacccct ttaagtaaac tggatataaa ctccaggact ttacgtgcat
     1381 tcagaaaata taatatctac caattggaag atcttttaag gttcattaaa tataacggat
     1441 ttgaagcttt ataccaaatg cctggcatag gcactaaatc tattgagcaa ttatatgaaa
     1501 agctgaagga taagaaaatt ttagtagatc aagacacttg ttttttattc ccttatcttt
     1561 ttgtatagat atgtcacact gatatacaat aatacatttt gtaggtagac aatgcacagt
     1621 ctttcgtagt atcggataag tcggcatcgg aaacaaaaaa cttgtgaaat agttactatt
     1681 atctctaatc ttctcttcag cccttcctcc aagcaccgtt acaactactt accagctatt
     1741 ggtgtaatca actctggtta tggctcgaaa agggatactc acagaagaag gtattaggca
     1801 tagagaacgg aaacatatcc tcccctcatt catagcaaat actaaatatt aaccgattaa
     1861 acctctcata cggtcttcaa aagcagatag agccgctttt gccccttctc ccattgctat
     1921 gattatctgt ttgtagggta cggtcgatac gtcgccagcc gcatagatgc cgggaacatt
     1981 cgtccgacaa tgcgcatcga ttacaatctc acccggtttg ttcgtttcga caacatcgcg
     2041 gaaaacgcca ctgttggctg ccaagccgat ttggacaaag attccgtcca ggtcgatcac
     2101 ccgctccgca tccgtcttac ggtcttttac acgaagaccc gtcaccttat cgccattacc
     2161 gagcacttcc aaagattggg aatgcaagaa aacttccaca ttcggcaagc tctttgcttt
     2221 ttcctgcaac acttggtcgg ctttcagttc gtccataaat tccagaaccg tcactttcga
     2281 acaaatgcct gccaaatcta tagccgcttc gatacccgaa tttccaccgc cgacaaccgc
     2341 tacgtgctta cctttataga acggaccgtc gcagtgaggg caaaaagcga caccttttcc
     2401 gatatagtcc gcttcgcccg gaacattcaa cttgcgccag cttgcacctg tcgccacgat
     2461 aagggcagga gcggaaaaac gttcaccggt agaagtggtc agaagttttg tcgatccatc
     2521 cagttcgact ttatccacac agcgatgctc cagtatatcg accggatagt cgttgatatg
     2581 tgtcagaagg tcgttcgcca actgctgtcc ggtagtctga ggaacggaaa tcaggttctc
     2641 gatgccgacc gtttctttga cctgtcctcc gatacgttcg gctatcactg cgacattcaa
     2701 gcctttacgt gccgagtaga tagcagaagc tgcaccggca ggtccacctc ccactattaa
     2761 cacatcatag ttcttaacag gtttttcaac agagttatca acaccccctt cattaattcc
     2821 gtattgggct tcgagcttgg aaagcaattc tcccaaatca ctacgcccca cattgatcag
     2881 cctgccatct gcaaaaacag aagggactcc ctgtactttc atggcctcaa cttctttttg
     2941 gttgatagca ccatccaccg tttcgtgagt gatacagctg ttgagagtag ccatgacatt
     3001 gagtgcctgc accacatccg gacaattggt gcaagtaaga gacacataag tcgtcagctt
     3061 gatcgggccg ttcaaagctc tgacacgggc acagatacct tcgtccggta tatttttacc
     3121 ttttccatcg caattcagga ccgctaacag caaagaagta aattcatgtc cgttgggtac
     3181 tgcacgaaac cggataccgg taggcatacc gtcttttaca attgtaaact gaagtccttc
     3241 gccatccgca acgctgcatg acaaatgatc cgagcatgat gccacatcac caagcaggtc
     3301 tattagctcc tgacggcttt cgtgatcggg agcgacttgt atatcaaata catattggga
     3361 taccagtccg gagaaaatac ccgaaagctg gtctttcatt gctgagtcta acataacttt
     3421 agatcttacc aaccaagtcg atgctcggct tcaaggttgc ttcgcctttt ttccactttg
     3481 caggacaaac ttcgttcggg tgagaagcaa cgaactgggc agcttcgact ttacgaagca
     3541 attcgtctgc attacggccg ataccgttat cgtggatttc agcaatcttg atcttacctt
     3601 cgggatttac caggaacgta ccgcgataag ccataccctc ttcttcaatc atcacaccga
     3661 acgcacgact taaagcccct gtcgggtctg ccagcatcgg atatttgatc ttacggatcg
     3721 tttcggaagc atcatgccat gctttgtgta caaagtgcga gtctgtactt acggaatata
     3781 cttcgacacc catttcctga aatttgccgt acttgtcagc catatcgacc aattcggtcg
     3841 gacatacgaa cgtaaagtcg gcaggataga agaaaaagat ggcccatttg cccttgatat
     3901 cttcgctact tactgtcttg aaactaccat tctgaaaagc ttgaactttg aattcgggta
     3961 cttgtgaatt gataattggt tccatgattt ttactattta atttgttact actatttttt
     4021 gtttacccta caaaggtaaa tcgtaagata ctgattgaaa gaatttttca aattgataat
     4081 ttttatctgc cgatagacgg acttctatcg gcaagcatac ttatctacta tgacaatagg
     4141 aagcaaagta atgttttccg gaacaataaa aatataccta attgtaggta aaataccttt
     4201 cggtcatacc atgtgattct ttaattatta cctttggatg ttaacttaaa aatattcgaa
     4261 gatgagaaga gtagtttgta taatacattt tcaacaagtc tattgctcgt tttcagtgca
     4321 tggctttctt catgcgtctc acaaataccc cttacaaagg aaaaaccggt aaacaattcc
     4381 acttatcaag tcgaatacct attcgaacac gaagggtgta aggtctatcg tttcagggat
     4441 atgggacatt acatctattt caccaactgc gagggagatg tgaccagtat tgaaagcgac
     4501 agcgtccgca cagtcaaccg gatcagccgt aaaccagtca ccatcagaga gcagacactc
     4561 gattaggctt acacggttat cccgtgttta ctaaagatcg ctttagcatt ggtcagacgt
     4621 tctgccgaaa gcggttccac acctttcagc ttataatcca ggccctgcgc ctcatactta
     4681 taggctccca ttgtgtgata aggcaaaagc tcggctttct gaaccacttt atagcgactg
     4741 acgtatccgg ctaatttttc cagatcctca tcattatccg tcaggccggg aacgaccaca
     4801 tggcggaccc atacgggaat gcctcgtttc tccagttcat caagaaaacg caaggtgtta
     4861 tcaagcttca cagcagtcag acggggatga agcccggcgt cgatcgtctt gatgtccaac
     4921 aaaaccaaat cgacatattc aaggacttcc aatgctttac cggaacagat atagccggaa
     4981 gtgtccaacg ccgtatgaat accgttctca cggcaaaggc ggaaaaactc tttaaggaat
     5041 tcaggttgta acaaaggctc gccaccggtc acggtaacac cacctttagc gataaaattc
     5101 ttatagcgta gcacttcggc aagcaacgct tcaggttcca gcagataagg cgtttcacgc
     5161 tttacctccc aagtatccgg attgtggcaa tacagacaac gaagcggaca tccctgcata
     5221 aaaacgacaa agcgaattcc gggaccgtca acggtcccga aactctctaa agaatgtata
     5281 cgccccaaca tattaatcaa tggacaatta taaactgctg ttgatggtac gcgagatgac
     5341 gtcgagctgc tgttcgcgtg tcagcttcac gaagttgacg gcatagcccg aaacacggat
     5401 cgtaagctgc gggtatttct ccggatgttc catcgcatct aacagcaagt ctttatcgaa
     5461 tacgttcaca ttcagatgct ggccgccatc gggcgtgaaa taaccatcta agaggctcac
     5521 taagttgttc acctggatat cgcgttcctt acccaacgtt gcaggagaaa cagcgaatgt
     5581 ataggaaata ccgtcatgcg catgctgaaa aggcagtttg gctacagaag ccaaagcggc
     5641 gacagcccct ttcgtatcgc gtccgttcat cgggttagct cccggagcga acggcgtacc
     5701 gcccggacgg ccgtcgggag tcgttccggt tttctttccg taaaccacgt ttgatgtgat
     5761 cgtcaggata gattgtgtcg gagttgcctt gcggtatgtc tgatgctggc gcagatattc
     5821 catgaacttc tcggtaatgt caacagcaat actgtccgtg cggtcgtcat tgtttccgaa
     5881 aggtacatat tcgccttcgc gttcgaagtc gacagccaaa ccacgttcgt cacggatcac
     5941 tttcactttc gtatcacgga tggcagccag cgagtcagca acgatagaaa ggccggcgat
     6001 accggttgcg cggatacgtt ccacatctcc gtcatgaagc cccatctcga atgcttcata
     6061 cgcatatttg tcgtgcatgt agtgaatgat cttcagagca ttgacataaa cttttgccaa
     6121 ccagcgcatc atctgctcgt atttctccat cacttcgttg tagtccagat actcgctggt
     6181 gatcggttcg aaacggggag ccacctgcac acccgatttc tcgtcacgtc cgccattgat
     6241 cgcatacaac aagcacttgg ccaggttggc acgagctccg aaatactgca tctgcttacc
     6301 gatcttcatc ggagacacac agcaggcgat accgtaatcg tcgccatagt ccggacgcat
     6361 cagatcgtcg ttctcgtact ggatggcaga ggtatcgatc gatacttttg cgcagaagtt
     6421 tttccagtta tccggagcat tgttgaacca aagcaccgtc aggttgggtt cgggtgccgg
     6481 gccgaggtta tacaaggtat gcagataacg gtaagatgtc tttgtcacca gcgaacggcc
     6541 gtcaacacct tgtccgccca gcgattcagt cacccaaaca gggtcgccgg agaacaggtc
     6601 gttgtattcc ggagtacgca ggaaacggac aatacgcagt ttgataataa actggtcgat
     6661 caattcctgt gcctcttctt ccgtcagctt gccttcgcaa atatcttttt cgatatagat
     6721 atcgaggaaa gtagaagtac gtccgagaga catggctgct ccatcctgat cctttacggc
     6781 tgccaggtaa gccagataca agaactgcac ggcttcgcgg gcatcctttg ccggacgtgt
     6841 cacatcgaaa ccataaccgg cacacatttt ctcaaatgct ttcagcgctt tgatctgctc
     6901 cgttatctcc tcacgactct gaatgatttc ttctgtcagt tcctgtatat cgagacgttt
     6961 ctggaaacgt ttcttttctt cgatcaggat ctgggttccg tacagaggta cacgacggta
     7021 atcaccgatg atacgtccgc gtccgtaggc atcaggcaac ccggtaatga tggcggaacg
     7081 acgtgccgca atcatctcgt ctgtataggc tgaaaaaacg ccttcgttgt gcgtctttct
     7141 gtatttggtg aagatttctt ttgtcatcgg gtccagatga tagccatagg cttccagact
     7201 gttttcgacc atgcggatac cgcctttcgg gaagataccg cgtttcaacg gggcgtctgt
     7261 ctgcaagccg acgattactt cgttttcctt atcgatgtaa ccgggtccgt atgtgtcaat
     7321 cccctgggga agcttcgttt cggcatcata tactcctttc ttcctttcaa ccttaaacat
     7381 ctcggttagt ttgttccaca ctttcttcgt tttctccgaa gagggtacga ggaacgtatc
     7441 gtctccgtta taaggtttgt aattgttctg gataaagtct cttacattga tctccttttt
     7501 ccaggtttct cctttgaact gcgcccagtt ctcgttttca aacttcataa gcttatcttg
     7561 tctatttcgg tttaggcacg caaagatacg tcttttcccc ctatctgaaa aggattgtaa
     7621 aggacgaggg atgttaaacc ggagaaaata cctacaaata gggataaggg aaataaaaac
     7681 gaagccccgg cagtacgaat accgccgggg cctgtttttt gtctgccgtc cggtcttcac
     7741 agagggaaaa gcagtagaac ttttaatttc attactttag tattattaat attaaatcca
     7801 accgcttgtt cgcctgtcgc agggtaattg aaaccataga tcaagaaaac ctcttacata
     7861 cggtttcacg caggttgtct agaattattt gattataaaa tgtcattgtg cctgtgtaag
     7921 ggtggttcgc taaccaccct tacgatagac agtattgttt tttagtatca atcgttactt
     7981 aacgatagct tttacagcag cttcaccttc aacagctaca actactacac ctgccggagc
     8041 agcgattgtt gcgttgtcag aagagattac tgtgttagct actacctggc ctaagatgtt
     8101 gctgataaca actttcttac cggcagcgcc tgcgattgtt acgttacctt cgccagcgat
     8161 cactttcact tcagatgttg cgatgccttc gttggctgta ggagcagact gtttttcgat
     8221 gacgaagcga taagcttcag acttgtcagc cttcatgtag aagtagttgt tgtactggca
     8281 tacatactgg ccatctttac ggatcacata ttcgtcacta ccttcttcgg cacgtacgat
     8341 ctggaactgg aagttcttca aaccaccctt gatcttcttc ggagcattat ctttttctgc
     8401 aaccaaaaca gacttgccgt caacgatagt acgcaaagta tcggaagaaa ccaattcacc
     8461 tgctttgaag atcaacttgg catcacctgt cgctttgttt tccaagttaa agcgatagtt
     8521 cttgcgagca gcgtagtagc ttgcagagtc tacggcattg tacaagaagt ttccaccctt
     8581 cgtgatatag aatgacggga tgttcaagtt cgaatgaacc gtgtcaaccc agaatgtcaa
     8641 gtcttcgctt gcttcattgg caatagccag gcgagcatct ttgttttcat ccattgtcat
     8701 gaaacctcca cgaacagctt cgaaagatat atgctgcgga acagcttcca aacttactaa
     8761 cggagattct tctaccatgt aagtcttcag accttcgcta agcagagttg tcaagtcgta
     8821 agccgaagca gtagcccaag gagcagtctt gccatctttc aatttatcgg caaccttcaa
     8881 gctattacct tcgagtttat tagtagtgtt ataatcaatc aagctaacag aaccatcaat
     8941 attttctttg ataacgaaat tcaaaccagt tgcacctaaa tcgaagttgt tagaacccca
     9001 tttcaaatac atattgtctt gatcagcatc aaaggcttta accttatatg tatagaaagc
     9061 aaccgtgtcc ttttctgtag aagtgatagg acggccgttc ttcacataca tatatgtatt
     9121 cagagcagtc aagaacttct cgctcttttc caattcgaac tgagcagcgt ccaaagcatc
     9181 actataagag aatatttcac cggtcatcaa acctttagca tttctcttgg cacccacata
     9241 gaattcagga gcagcttcat cgttcttagc caaggcgaat gtcaccagac ctgcaccttc
     9301 ttcacggttt acgaaagaag caaacttgtc ttctacagtt accggattca acgcaatctt
     9361 ggttgtagcc catttaacac cattaccgaa tgtaacgtct ccgtttacat cattaccatc
     9421 aatatattca ggataaacat cccagttatt gctattatca gtcgtatata caatgtaagc
     9481 atcaccttct ttgaacaaag acaattcaat ttcaacacca gactgacggt ttgcaaacgt
     9541 tacctttttg tattttttgg tatccgtgtt gtaatcgcta atctttttaa caacaaactg
     9601 gaagcgcgga tcctgttcat tgatttcttc taccgaagcg agacggagac cactctgggt
     9661 tgcatgttgg tcaactgtca accactggcc atactcgctt accccttctt tgtcttcacc
     9721 gctgacgaac tggattgtgt agatagccgg agcatccgta tcgttcaaca gacccttaac
     9781 atcataaagt gtttcgtttg tagccttgaa tgtaagggca tgatcttcat cattcgtgat
     9841 catgtaatct acatcctggt cttttacaaa accgatgaac tgtttaccgg cagcaatatg
     9901 gtcatcctta ccttcttctt tcaaaacgcg agcgttgtta gtataaatct gataagttgt
     9961 ttcgtccaac aaagtcgggt tgatcactgt gaaacaagcg ttacccacat agatttcatc
    10021 cttcttagaa acttctcctg ccacattgtt aaaatggaag tcagagccct ttacctttgt
    10081 aaaccagaac cctttacctt taccacgcgg tacttcgttg atgttcaggt ttttcaacgg
    10141 atcaacagct acgaatgtag cagcttcgaa ttcttctttc ttgtccaatt gggcatcttt
    10201 gcctttcaat gtagccggca tgttttcgtc tacaacaaca aagtatgtac cggcagggac
    10261 attagcaata gttcctgtta caacttcgaa cgccttcaaa ttcagatatt catcaccgtt
    10321 cttgaagatg ttgccttcaa acttgtcacc ggcagatgtc agattgaagc cttcgccacc
    10381 cattgtgtcg ttcatcttgg cgatgtcggc attctgttct gcagtgtatt tgcaaaggat
    10441 aagagcggta ccagtttcat ctaccttaac cacattgttt gtctgggcca atgctaacgc
    10501 atttgcaacc gtcacccctt tcagatacaa gattccgttt ccatcgtttt tgaactcaac
    10561 atttgcagct gtcgtaccgc ctacagcggc aaagatagag ctgtattctg ttccaacctc
    10621 agctttgcca gcttttgacg cattggtagt caaatttccg ttaagatcga aagtcagata
    10681 cttgccagtc gttttgtttt gtaaggtata agtgtacgac tttgtaccag cagcatttgt
    10741 ttcttccttt acagtgaatt tccaaacagc atctgccaac ttcgcagtag aaagctcttc
    10801 tgctttagta gtcaatacgc taccatttaa agtagctgtc aaagccaagt catcattact
    10861 tatcccatca ttcgtcaagt cacgaaggat aatgtactcg cctgaagtca ctttgtcatt
    10921 ttcaaacgtt accggctcca aattattggg caaaatttgc gcagaagcga acgcacttgt
    10981 cagcaggaac cctgccatta gagtagaaaa cttcttgttc ataatctaaa atgtttaatt
    11041 aataataata tgtatattga atatcgttct tacttcctgt ttaacaggtt tttaccaaat
    11101 tcctgtattt tgacgagata aaacgtacgt tttttttagt catttttgag gggctttcgg
    11161 gagggtttgt gttggaaagc tggtttttcg tacttgttaa gctatctgat tgataagaaa
    11221 gaatatagaa aaggaaaaat aattggaaga aaggattgca ggttcaaaaa gtagttgtat
    11281 ttttgtgcag tgaaaatggc gaaagaaaac gtacgttttt tcgctatttt tcttcttata
    11341 cccatatact tcttattagc aatgacttac attgcaaaaa gtgcctaaag ccatataaaa
    11401 aaagagctgt tttcaaccgc tcgccaaact tctttacatc ttcatcaaaa caaagataat
    11461 caatcaccta taagattaac ttcctttatt tacattggag gggaaaaaca gcaaaaacag
    11521 caggtttcgt aatttcatct tggaaaagct cccccttctg ttaaagatat acaaaatacg
    11581 gagtattggt tgcttagctc aataacagct tcaagacttg caaaacctta cattattatg
    11641 tatctttaca tcaacgtccg tcacagacgg atcaaacaac tataatacgt taatacaata
    11701 tatgaaagaa aaaatcgact cttccgacat ccccacctcc tatctgctct gcatgaaaca
    11761 agattgcccc aaagccacta cttgcttgag gagaatcgca gaacaacaga tcggcgacga
    11821 agtcaaactg tggcacgtca tcagccctaa ataccaagag aagcaaaccg accgatgtgc
    11881 ttatttccgc cctgccgata aactgaccta tgcgctcggt ttcatcggga tgctggaccg
    11941 gatgccctac aaactgatgc aggaagccat ttgcaagctg atgagacggt tcggacgcag
    12001 gacttactac cgcgtgcgaa aaggcgaacg cccgctctcg ccggacgaac aaaaaagcat
    12061 gttgaacata ctgaaacagt gcggtatcaa cgatcccgga aagttcgatg cctacttcga
    12121 ggcatacgac tggtaagttc acatgacgca acttgcctac gtattggttg tgccatacct
    12181 atgtaacgac cgtttcctcg gcatgaaacg gttgtgccaa gcttatgtaa caggcgtttc
    12241 ctactcagga aacagttgtg ccaagccgat gtaattgttt tggcacagcc ggagcagcaa
    12301 acagaccctt gcgggaacaa gtccaagact cgacgccgaa cagattccgg acagaagcga
    12361 atgggaaacg gaaacataaa aaagaagcct ctcttcacag agaggcttct tttttatacc
    12421 gaaaataacc aataaaaact tttcgatata gttaatcatc ttatatgctt acataattga
    12481 caaaaggttt tgatatagcg attatactaa tagtgttact ttcttaatga cattgcaaag
    12541 atacgggtac ttcccacctc ctacaatacc tatatgtgag taaaaaaacg tcttttacta
    12601 cctaatcaag gtgatattca ggcgcaatac ctacaaatgg gtaacatcgg aaccttttta
    12661 cctactaatt gcgattgcac accgttgaca gcccctctaa ttttgccaaa aattaaaaaa
    12721 cgcaatgaaa aggttaacta atttattagc aatcactcta ctcacctctt gtgtaacggc
    12781 atttgcacag gaacaagaag aaacaacgac agaaaaatcc gcagtggaac aatccgcaga
    12841 catttatgcc gacggatata acaagttccg cttcggcgga tatggggaga tcctcgcaaa
    12901 ctttatggac tacggcatca accgtttccg gggtacggac aacggaagca agaaagacca
    12961 tcgcaattcg atctccatac cccgttttgt cttggccttc gattacaaat tcaattccca
    13021 atgggtatta ggagcagaaa tagaatttga ggctggaggt acgggaagtg cctatgagat
    13081 agaaaacaca gaaaacggag aatacgaaat ggaagttgaa aaaggcggtg aagttgcttt
    13141 ggaacaattc cacatcacac gtcttatcca tccggccttc aatgtccgtg ccggtcattt
    13201 gatcgtcccg gtcggtttga ccaacgagca tcacgagccg atcaacttct tcggaacttc
    13261 tcgtccggaa ggcgaaacga ccatccttcc ttctacctgg cacgaaaacg gtatcgaagt
    13321 gttcggtacg ttcggccgag gctacacacg tttcaactac caggctttgg tcgttgccgg
    13381 attgaacgcc aacgggttcg accgcaatac atgggttgcc ggcggcaagc agggactatt
    13441 cgaaacagac aacttcacct caccgggcta tgtggcccgc ctgaactatt taggagtacc
    13501 gggattgaaa ataggcggtt ccttctacta ttgccacaat acgggagcca attccgacaa
    13561 accggaaaca tacgtcaaat atggaaacat acctttgcgc atctatacgg ctgacctgca
    13621 atacaaaaac aaatatgtca ccgcacgcgc aaacatgata tacggcaacc tgagcaaagc
    13681 cgacgacctc agcagtgtca acaaccacca aagcggcggt tctccttata cacagacaac
    13741 cccgatcgcc aaacgtgcgg tcagctacgg tggtgaagtg gggttcaacc tgcgtgcggt
    13801 ttgtaaagac aatatgagcg tacccgtaat ctatccgttc gtccgctacg aatactacaa
    13861 cccacaggaa aaaggcgaag gcaagcacac gatggattta cgcaacaaag taagcatgtg
    13921 gacagccgga gccaattggt atgctttacc taatcttgtc gtgaaagcag actatacaac
    13981 acgcaaaatc ggaggcggca aatataacag cgaaaacgaa ttcagcttgg ctatcgccta
    14041 tatcggctgg ttcctcagca aataaaaaca atataaacaa attaataact tatcaataaa
    14101 aatgaaaaag aaaaattatt tctatctggc agccttatcg ctcgccatga cattctcgat
    14161 gggagcatgt agcgacaaca acgaccccaa tccggatggt ggcggaaaag atccggtcaa
    14221 cctggattac agttctgaaa acgccagtgc atggggtaac tatatgtata acgttgcaat
    14281 gttgctgaac gacgatgcaa ccatgctcta caattcttgg gtaaccgact acgtcgatga
    14341 gcagggttca cacggcccat atgccacgat tttcaaagac cagactgccg gagcttacca
    14401 aagcccgctc tcgtgtatcg aggaaatgat cgaaagcggt atgtggaaca tcgccaacga
    14461 agtaggtgac gccaagatca aggacccgta taccaaatat accagcggtg acaaggaagg
    14521 cggtctctat gccgtcgaat catggtatag ctggcattcg cgcgacgact atacgaacaa
    14581 tatcttctcc atccgtaaca catactacgg ccgcatcgac gacaacgacg tgtccaaagt
    14641 agacggaaac ctgagtgcat tcaactctta caaagatttc gacgatgaag gagacatcgc
    14701 agaacactcg ctttcaaaac tgatcgcttc aaccaacccg gctctcgacg aagaaatcaa
    14761 aacgctgatt ttcgcttctg caaaggcgat ccaggctatt ccgcaaccgt tccgcaacaa
    14821 catcgacagc gaagagtccg ttgccgcaat gaacacttgc atggaactgg ccaacctgtt
    14881 gttaaatgaa gtaaaaccgt atgtaaacca aacattcggc gatcctgaat acgacgatga
    14941 ccttgatgca atagccgaac agtttgtcga tgcggtcgtt cttcctactt ataaagactt
    15001 gcaggaaaag aacaagcttt tgctggatgc ggtaaaccag ttcagacaaa acccaagcaa
    15061 cgacaacttc gaaaaggcct gcaatttatg gatcacggca cgcgaaccgt gggaaaagag
    15121 cgaagctttc cttatcggtc cggtcgccaa cttaggtctg gaccccaaca tggacagctg
    15181 gcctttggac cagaacggta tcgtacaggt attgaattca caaaactggg atgacctgga
    15241 atggagcgga aactttgacg aagaagatga agccatcgga gccgcacaga gcgtacgtgg
    15301 ttaccataca ttggaatatc tcctattcaa agacgggcag ccccgcactg tcgatggagc
    15361 aaaataaaca tgcctctgag acataaaact tgataataga tcatgacaaa ccttgaaaca
    15421 gcagacaaat gcccgctgtt tcagggtttc agagtaatta cacaatgcga ctcgcgttat
    15481 tcggaaataa attcagaaaa ccaataaaat gatatgaagc aatcttacct gttaacatcc
    15541 tcgctattcc tgctctttgc atgcgcagct tgtgaagagg acgataaaat ggatatggat
    15601 aaaatagatg tcccgaacgg atatgcgctg tcagcaggga cttcaacgat tttcctaaac
    15661 tcatcggtcg cctacgatac gaacgccgac tggataacag gagccaactc gatccgtttc
    15721 aacaacggcg acggtctcta cgacgatgta cgcaccagca acaatggcga cggaggcggt
    15781 ctcggacctg tttatgccgg ctattcctgc ggcagttgcc atcgcaacgc aggaaggacc
    15841 aaaccgacat tgtgggaaaa tggcggatcg ggcaactacg gtttctcttc catgctggtc
    15901 tatatctccc gccgcaacgg tgctttcttc cgcgactacg gacgtgtatt gcacgaccaa
    15961 gccatctacg gcgtcaaacc ggaaggtaag ttgtccgtca catacgacaa gcagactttt
    16021 tccttccccg acggagagac ttacgaacta tgcaaaccca attacacgat aaccgaatgg
    16081 tataaagaca gtatcgcccc ggaagatttg ttctgcaccg tacgcatccc gttacgccac
    16141 gtcggtatgg gacagatgat ggcaatcgac cgcagggaaa tcgaagcgct cgctgccaaa
    16201 agcaattatc cggaatatgg tatcagcgga cgttgcaact atatcaccga gaagggtgtc
    16261 accggtgtcg gcctttcagg aaacaaggca cagcatcttg acctgaccgt cgaactgggc
    16321 ttttcaagcg atatgggcgt gacaaacagc cgctatccgg aagagatttg cgaagggcag
    16381 gctcagatca accaaggcag catgatggga ctctcgtacg accagctcga catatcgacc
    16441 gccgatatgg aagatgtgga cctttacatg caaagcctcg gcgtaccggc acggcgcaac
    16501 ataaacgacc ctcaggtcat cttaggagaa caaaagtttt acgaagcgaa atgccatctc
    16561 tgccacgtca ctacgctgca cacgcaagcg ggcggttcca cactgctcaa cggcacacgt
    16621 ttgccatggc tcggcggaca gaccatacat ccttattctg atttcctact gcatgacatg
    16681 gggtcggaga tcatgggagt cgggttgaac gacaattatg tcagcggcct ggcacgagga
    16741 aacgaatggc gtactacgcc gctttggggt atcgggctgc aggagaaagt caacggtcat
    16801 acctatttcc ttcatgacgg acgcgcccgc aacctgaccg aagccatcat gtggcatgga
    16861 ggcgaagggg aagcctccaa aaatttattc aaacaaatga gcaaggaaga gcgtgaggca
    16921 gtgatcgcat tcctcaactc cttataattt atccataaga caaactaaaa tgaaacaact
    16981 gataatcaca attgcagcat tattactatt gccgttggcc gtcatggccc aatatgagga
    17041 agatacggaa aacggtgtcg tatcactaaa cggcaaagaa ggttttacaa tcgct
//
