LOCUS       c00111_gnlPro..        14231 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KJPOEMBI_111.
ACCESSION   c00111_gnlPro..
VERSION     c00111_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 18:54:50
            Original ID  :: gnl|Prokka|KJPOEMBI_111
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14231
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14231
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1239:4231]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1240..4231
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14231
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14231
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             3..812
                     /locus_tag="ctg111_1"
                     /transl_table=11
                     /translation="TYMVEESPLVSLEAVPQHISFEAVRGGFMTMDENKDARLAIANEA
                     SEDLTFWVDTVHSNLNIPSFYITKGGNFLYNAVDSASYYAARKNYRFNLENKATGDAKL
                     IFKAGELVSSDTLRTIVDGKSVLVAEKDNAPKKIKGGLKNFQFQIVRAEEGSDEYVIRK
                     DGQYVCQYNNYFYMKADKSEAYRFVIEKQSAPTANEGIATSEVKVIAGEGNVTIAGAAG
                     KKVVISNILGQVVANTVISSDNATIAAPAGVVVVAVEGEAAVKAIVK"
     CDS             1240..3480
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg111_2"
                     /sec_met_domain="Gly_radical (E-value: 3.8e-45, bitscore:
                     144.4, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.7e-283, bitscore:
                     932.3, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENENWAQFKGETWKKEINVRDFIQNNYKPYNGDDTFLVPSSE
                     KTKKVWNKLTEMFKVEREKGVYDAETKLPQGIDTYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTDEMVAARRSAIITG
                     LPDAYGRGRIIGDYRRVPLYGTWILIEEKKHFQKRLDIQELTEEIIRSREEITEQIKAL
                     KAFEKMCAGYGFDVTRPAKDAREAVQFLYLAYLAAVKDQDGAAMSLGRTSTFLDIYIEK
                     DLREGKLTEEEAQELIDQFIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTKTSYRYLHTLYNLGPAPEPNLTVLWFNNAPDNWKNFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQYFGARANLAKCLLYAINGGRDEKSGVQVAPRFEPITS
                     EYLDYNEVMEKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMGLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVKVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVDITEKFM
                     EYLRQHQTYRNATPTQSILTITSNVVYGKKTGTTPDGRPGGTPFAPGANPMNGRDTKGA
                     VAALASVAKLPFQHAHDGISYTFAVSPATLGKERDIQVNNLVSLLDGYFTPDGGQHLNV
                     NVFDKELLVDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINNRL"
     CDS             3509..4231
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.1;
                     E-value: 4.5e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg111_3"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-35, bitscore:
                     114.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGRIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWEVKR
                     ETPYRLEPEALLAEVLRYKNFIAKGGVTVTGGEPLLQPEFLKEFFRLCRENGIHTALDT
                     SGYICSGKALEVLEYVDLVLLDIKTIDAGLHPRLTAVKLDNTLRFLDELEKRGIPVWIR
                     HVVVPGLTDNDEDLEKLAEYISRYKVVRKAELLPYHTMGTYKYEAQGLDYKLKGVEPLS
                     AERLANAKAIFRKHGITV"
     CDS             4827..6803
                     /locus_tag="ctg111_4"
                     /transl_table=11
                     /translation="MFGRFTSLLTVASLVCWGIVSHVSAQIPSLSADIMALYGYQMDGR
                     TSLPLGTNENISIYNVYDAPVDGCYFGLSNPKNTYDPMGIDCEACLEAGGRLKINGSYV
                     WGLTSTSDKIYWGTTNNLLCLAFAIVGEAATTAYETSDWTCDCPEGSSNEALPPRVYVY
                     EPNTGVVKDLTPDDEAVKGTACTGLRSAGTLNDVVFLGGPDTKHGLTVYAYSTKDDTFL
                     GLSHFENVSNIEGFQVTNIRKWLVIDGVLYCGVRYVHGEKSGGAILRWRGNAENPFQFE
                     VVGYTAAEAAELAFHDGRIYVGGWPAMIFRSPELPEGGLTADHAATWETVWSMSDYEID
                     PFVLRLTGIGGFKSYKGRLYWGFLHIPWAYLSVLPAYYGLTSQEDILAAVLGAWRSSAL
                     FSASDFSSKDDVVMLYGEEKLPQFDRAKKKWEIKPNASGYKPKWGRSGAGNLFLNYIWS
                     MEVYNDKLYIGTMDMSDLIEPALNSSEFSLGGMNSSLVLNMLKVDKKQYGYDCLVIDDP
                     EKEPSLVTNDGFGNPAAYGIRNMLVHDGQLYIGTANPLNLHEQGGWSLLTLTERSAPTA
                     SAKQPEVADLLYRQTDSYVEISSLKGESIESVTLVDMAGRVLRKEKGDSPTAVLVTDGL
                     PGGVYVVTVRTNAVTKSFKIKVR"
     CDS             6837..11615
                     /locus_tag="ctg111_5"
                     /transl_table=11
                     /translation="MKKSTLRKGGVVLLGAMTLFGTGVLSWANITEAVNPPIEKAQPGW
                     TKVTNGKFGTESTDLDKNLRDYVKMDLTQAAKPSHDNVARYCSTFDFSNLGVDLLPGLA
                     ISFANTGGNEVVNGLFQAWSYDEVKNHEPIKSSSVFKVALNEEGTKYGLGIYPNYSANA
                     RVEFVYSTRGLSDVNRIQVKLDSYGDKAEINVSRTYKVHATIYNLDGTKVKDLNEYTYV
                     ADKNHLGKPEEWAIQTSNVNAGENLKVGDLDNKIIRVIITSENPVQDGQTDVTEPLLVI
                     SDVHIDFLRPEVTLAVADNEVLEAGAGRTTDCDLKTLETTVKFWNTLDMTELGVAARGD
                     IYPNEGNELSEELRYEGERPAFYEISAAHPFRLHGIKVSNVSDPTKEDKFFDFAEIASK
                     NGKIGKDVTKFTTGALVGQDSLITYRIPREFFVEANGEKFANEYKVTMTYAFEPLTVGT
                     FDDEYIKATTSARSTDTAKVVLKGNSVPVYKEADELTFTKYREVQYANAIEFKNLPKFA
                     DVDDGFYLNNDTKADENATERYDDDAVQIGWRVVTKDNVYFIRQEGATHILPVKATAPE
                     YEIYNYADINWNLNTSIVFEDAIFPDEPLEGPLSIIDCTGKLEKNVISVHPVFRCVRKD
                     INISNSESLNPIEKFALADELTYGVADYKYTGADLKAGKDEAVYEGPVVAKCAQAFVWY
                     RFEGDSTALGGAMLAKAIDAMDINTGRVDAYFSGYRTGALDETAMRSREHTIRIFAGEN
                     VEKDANGIATIKVFKEKFNIDLWANDVTGDKNWLPAEGYSYKDDSFEQTTNGFFFTYNA
                     KQQYVKASWSATSNANDAASAWRGQNVTDTLYIKVDLSTPAMQAALKEDGIPVQVVYRP
                     YNERYTLLEGLRDLFRGDIPLWANSWNHVAQFGIVVGNAYNEFYTTGSTSKGLITTMTT
                     DHSIASYANFADFVNNRFGDLPNGHIHGIYKDFYAKDHGSYYVGSECLNGIKRDHNFIV
                     AGLNLINNVELYAYEAAPGAFKRTVLPILGSVAEDGSLVPNEYGEALFIVSTDFAPKAA
                     DKAKAEVENITVNGDLVAMNYLKDEVVLKPVQTAGHDSVFVYDLDKENHGYLFDGKLNI
                     FNHYAAYEADSVSTVIKGDVRVPELWLSSDRAGKDKIAAYSFDEVLAGESKDGVIYVQG
                     RDLPLSKDDPMLDGNVIEAVLPIVADGVYTSDEEIDIYTAAKDTLNEEGAITGTIAWPV
                     TITATPDVDDLCNTEGVFSVDGLCENLKQELSLTHAPVLAGGFAVDVIKTNGGRAEINW
                     ESVPGADYYTVQIGNTVVDPISENVFISQVLAENNSIKVTLKNGTGKDINKDIAINYFL
                     ELTGYDKNGKVVVAPEVISREEINPDVWVSEELVVKSFDAELSEDIIYKIRLCEYDTNR
                     QIDVYEFDNTYSHLYRKTVDGGVILMNRGSFNTADWSTVKVEYPTADFKALATSEKTTD
                     TKVTVVNMAASTNYEVRVIAHSDCEKVNASRSALADIHTSIDEGGSGNVAFEGIEAPTA
                     NETINAATVKVVAGKGQVVVMNAAGKKVVVNNVLGQTIANTVMTSDNVTIAAPQGVVVV
                     AVEGEKAVKAIVK"
     CDS             12135..14030
                     /locus_tag="ctg111_6"
                     /transl_table=11
                     /translation="VAEFGRFFQVDNGIEVLALEPQPTSGLVVIVAAQAIGQFRSTVEV
                     ISSAGGHLQGDRFGCCLVEIDLFREDAAVSGRADSNGFHLCILFDAERRFVFRGGCRRF
                     AAVERVMDIGVPFGFERYDDFPFVTIGSEGGANVEDVFGVIVAQTVVKLGHADQARQEC
                     LEVFRCVCPLYFGQCVHTRQYHVFDLAECRDIFCPEVRLHADHIFPVFFRYSGSRFERI
                     DAFQRQITADGKRVVFRVGRLVIVEIEVRVGRHDHIMFLFGSFDTAVYATPAHHRCVRS
                     QSAFQDFVPTDDMPSFAFDEFLHAFDDIALQAFFGRVFVVPFETFRLDAGLALRATFPT
                     HFRAFVTAYMYIFGREEVDHLAEHVFEEDHGFFVTGTDHLVRNAPLCPHFVRSARTTQF
                     GVGRDGCQLVSRKVYFGDDRNETFLGISDHVANFVLRVKHAFAIRLAVIFAGVASDDCL
                     PALCPYPGQFRIFLDLDTPALVVRQMPMETVHVVQGKNVDKLLDRVGREEMAGNIEVHA
                     AIRETRIVVDADSRKFDGHTFGHGGERLAQGLHAIENAGVGCSGDLDAVLADQQAVAFR
                     VPDVGSDRQMNAFVRVSCAHFRFIARGLFDVGGEETGGLFHLCITFLIRDRGRRF"
ORIGIN
        1 agacttacat ggtagaagaa tctccgttag taagtttgga agctgttccg cagcatatat
       61 ctttcgaagc tgttcgtgga ggtttcatga caatggatga aaacaaagat gctcgcctgg
      121 ctattgccaa tgaagcaagc gaagacttga cattctgggt tgacacggtt cattcgaact
      181 tgaacatccc gtcattctat atcacgaagg gtggaaactt cttgtacaat gccgtagact
      241 ctgcaagcta ctacgctgct cgcaagaact atcgctttaa cttggaaaac aaagcgacag
      301 gtgatgccaa gttgatcttc aaagcaggtg aattggtttc ttccgatact ttgcgtacta
      361 tcgttgacgg caagtctgtt ttggttgcag aaaaagataa tgctccgaag aagatcaagg
      421 gtggtctgaa gaacttccag ttccagatcg tacgtgccga agaaggtagt gacgaatatg
      481 tgatccgtaa agatggccag tatgtatgcc agtacaacaa ctacttctac atgaaggctg
      541 acaagtctga agcttatcgc ttcgtcatcg aaaaacagtc tgctccgaca gccaacgaag
      601 gcatcgcaac atctgaagtg aaagtcatcg ctggcgaagg taacgtaaca atcgcaggtg
      661 ctgccggtaa gaaagttgtt atcagcaaca tcttaggcca ggtagtagct aacacagtaa
      721 tctcttctga caacgcaact atcgctgctc cggcgggtgt agtagttgta gctgttgaag
      781 gcgaagctgc tgtaaaagct atcgttaagt aacgattgat actaaaaaaa caatactgtc
      841 tatcgtaagg gtggttagcg aaccaccctt acacaggcac aatgacattt tataatcaaa
      901 taattctaga caacctgcgt gaaaccgtat gtaagaggtt ttcttgatct acggtttcaa
      961 ttaccctgcg acaggcgaac gagcggttgg atttaatatt aataatacta aagtaatgaa
     1021 attaaaagtt ctactgcttt tccctctgtg aagaccggac ggcagacaaa aaacaggccc
     1081 cggcggtatt cgtactgccg gggcttcgtt tttatttccc ttatccctat ttgtaggtat
     1141 tttccccagt ttaacatccc tcgtccttta cgatcctttt cagatagggg gaaaagacgt
     1201 atctttgcac gcctaaaccg aaatagacaa gataagctta tgaagtttga aaacgagaac
     1261 tgggcgcagt tcaaaggaga aacctggaaa aaggagatca atgtaagaga ctttatccag
     1321 aacaattaca aaccttataa cggagacgat acgttcctcg taccctcttc ggagaaaacg
     1381 aagaaagtgt ggaacaaact gaccgaaatg tttaaggtgg aaagggaaaa aggggtatat
     1441 gatgccgaaa caaaacttcc ccaaggaatc gatacatacg ggcccggtta tatcgataag
     1501 gaaaacgagg tgatcgtcgg gttgcagaca gacgccccgt tgaaacgcgg tatcttcccg
     1561 aaaggtggta tccgcatggt cgaaaacagc ctggaagcct atggctatca tttggacccg
     1621 atgacaaagg aaatcttcac caaatacaga aagacgcaca acgaaggtgt tttctctgct
     1681 tatacggacg agatggtggc tgcgcgccgt tctgccatca ttacggggct gcctgatgcc
     1741 tacggccgcg gacgtatcat cggtgactac cgccgtgtgc ctctgtacgg tacctggatc
     1801 ctgatcgaag aaaagaaaca tttccagaaa cgtctcgata tccaggagtt gacggaagaa
     1861 atcatccgga gccgtgagga gataacggaa cagatcaagg cgctgaaagc cttcgagaaa
     1921 atgtgtgccg gttatggttt cgatgtgacc cgtccggcaa aagatgcccg cgaagccgtg
     1981 cagttcctgt atctggctta cctggctgcc gtaaaggacc aggatggagc ggctatgtct
     2041 ctcggacgta cttctacatt cctcgatatt tacattgaaa aggatctccg cgaaggcaag
     2101 ctgacggaag aggaagcaca ggagctgatc gaccagttta tcatcaaact gcgtattgtc
     2161 cgtttcctgc gtacaccgga atacaacgac ctgttctccg gcgaccctgt ttgggtgacc
     2221 gaatcgctgg gcgggcaagg cgtcgacggc cgctcgttgg tgacaaagac ttcttaccgc
     2281 tatctgcata ccttgtataa cctcggcccg gcacccgaac ccaatctgac ggtgctttgg
     2341 ttcaacaatg ctccggacaa ctggaaaaac ttctgcgcga aagtatcgat cgacacctct
     2401 gccatccagt acgagaacga cgacctgatg cgtccggact atggcgacga ttacggcatc
     2461 gcctgctgtg tgtctccgat gaagatcggc aagcagatgc agtatttcgg agctcgtgcc
     2521 aacctggcca agtgtttgtt gtatgcgatc aatggcggac gcgacgagaa atcgggtgtg
     2581 caggtggctc cccgcttcga accgatcacc agcgagtatc tggattacaa cgaagtgatg
     2641 gagaaatacg agcagatgat gcgctggttg gcaaaagtct atgtcaatgc gctgaagatc
     2701 atccactaca tgcacgataa atatgcgtat gaggcattcg aaatggggct tcatgacgga
     2761 gacgtggaac gtatccgcgc aaccggtatc gccggccttt ctatcgttgc cgactcgctg
     2821 gctgccatcc gtgacacgaa agtgaaagtg atccgtgacg aacgcggttt ggctgtcgac
     2881 ttcgaacgcg aaggcgaata tgtgcctttc ggaaacaatg acgaccgtac ggacagtatt
     2941 gctgtcgaca ttaccgagaa gttcatggaa tacctgcgcc agcatcagac ataccgcaat
     3001 gctacgccga cacaatccat tctgacgatc acatcaaacg tggtttacgg aaagaaaacc
     3061 ggaacgactc ccgacggccg tccgggtggt acgccgttcg ctccgggagc caacccgatg
     3121 aacggacgcg atacgaaagg ggctgtcgcc gctttggctt ctgtagccaa actgcctttc
     3181 cagcatgcgc atgacggtat ttcctataca tttgccgttt cacccgctac gttgggtaag
     3241 gaacgcgata tccaggtgaa caacttggtg agcctgttgg acggctattt cacgcctgat
     3301 ggtggccaac acctgaatgt gaacgtgttc gataaagaac tgttggtcga tgcgatggag
     3361 catccggaga aatacccgca acttacgatc cgtgtttcgg gctatgccgt caacttcgtc
     3421 aagttgacac gcgaacaaca gctcgacgtc atttcgcgca ccatcaacaa ccgtttataa
     3481 tcgtcaattt tcaattgtcc attctaatat gttagggcgc atacattctt tagagagttt
     3541 cgggaccgtt gacggtcccg gaattcgctt tgtcgttttt atgcaaggtt gtccgcttcg
     3601 ttgcctctat tgccacaatc cggatacttg ggaggtaaag cgcgagacgc cttatcggct
     3661 ggaacccgag gcgttgcttg ccgaagtgct gcgctataag aattttattg ctaaaggtgg
     3721 tgttaccgtg accggtggcg aacctttgct gcaaccggaa ttccttaaag agtttttccg
     3781 cctttgccgt gagaacggta tccatacggc gttggatact tccggctata tctgctccgg
     3841 caaagcattg gaagttcttg aatatgtcga tctggtcctg ttggacatca agacgatcga
     3901 tgccgggctt catccccgcc tgactgctgt gaagctcgat aacaccttgc gttttcttga
     3961 tgagttggag aaacgcggca ttcccgtgtg gatccgccat gtggttgttc ccggtctgac
     4021 ggataatgat gaggatctgg aaaaattggc cgaatacatc agccgctata aagtggttcg
     4081 gaaagccgaa ctcctgcctt accacacgat gggaacctac aagtatgagg cacaaggctt
     4141 ggactataag ctgaaaggtg tggaaccact ttcggcagag cgcctggcca atgcaaaagc
     4201 aatcttccga aaacatggga taaccgtata aaccgcatcg gattcctttc atgatactat
     4261 ttgattctca aagaatattc ctttctacct tcctgtaatt ccggggtttt atggatagtt
     4321 tttctttttg ctgcctaaaa ccccttttgt cccctttttt tcttcttttt ttcaaaaaca
     4381 gtaatttttt acttgtagta ttacttgaat aaaaacgtgc aagttcttgt aacttagaaa
     4441 tatatttctt tgatgcaaaa taacggaaaa gcctgtttct gaggggtgaa ttctgctcat
     4501 ttcttgtttg taaattcttg tggataagaa agatagcgga agaaaccaaa atgactaaaa
     4561 aaacgtacct ttttattcgc catttttcag ctacaaaaat acaactactt tttaaacctg
     4621 caatcctttc atcaaattat tttcccattt ctatattctt tcttatcaat cagatagcta
     4681 aacagggacg aaaaacctgc tttccgatac aaaacgctcc aaagcatcgg aaaaatgaca
     4741 aatttaaacg tacgttttca ttgtcaacgt acatttttta agagttcatg aataagatgc
     4801 gaatgttgta agaaaagaaa tagcatatgt ttggacgttt tacatcttta ttgactgtgg
     4861 cttcactggt ttgttgggga atcgtgagtc atgtttctgc gcaaatacca tctttgtcgg
     4921 ccgacatcat ggctttgtac gggtatcaga tggacggtcg taccagcctc cctctcggta
     4981 cgaatgaaaa catatctata tataatgtat acgacgctcc tgtcgatggg tgttatttcg
     5041 gtttgagcaa tccgaaaaac acctatgatc cgatgggaat tgattgcgaa gcctgtttgg
     5101 aggccggagg gcggttgaag ataaatggtt cttatgtatg gggcttgaca agcacaagcg
     5161 ataagatata ttgggggacg acaaacaatt tgctttgcct tgcatttgcc attgttggcg
     5221 aagcggctac tacagcctat gaaacatccg actggacgtg cgattgtccc gaaggttcga
     5281 gtaatgaagc tttgcctccg agggtttatg tctatgaacc caataccggg gttgttaagg
     5341 atttgacgcc tgacgacgag gcggtcaaag gcacggcttg cacagggctt cgttctgccg
     5401 gaactttgaa tgatgtggtc tttttaggtg ggccggatac caagcatggg ttgacggttt
     5461 acgcttattc tactaaggat gacacattct tgggacttag ccatttcgaa aatgtgtcta
     5521 atatagaagg ttttcaggtg acgaatatcc ggaaatggtt ggttatcgat ggtgtgcttt
     5581 attgtggcgt acgctatgta catggcgaaa aatccggtgg tgcgatcctt cgttggagag
     5641 gaaatgcgga aaatcccttc cagtttgaag tggtcggcta tactgctgca gaagcggcag
     5701 aattggcttt ccatgacgga cgtatctatg tagggggatg gcctgcaatg attttccgca
     5761 gcccggagct tcccgaaggc gggctcactg ccgatcatgc ggcaacttgg gaaactgttt
     5821 ggagcatgtc cgactacgag atcgatcctt ttgtgttgag actgacgggt atcggcggct
     5881 ttaaatccta taaaggccgt ttgtattggg gcttcctgca tattccttgg gcttatctgt
     5941 ctgtgcttcc tgcttattac ggtcttactt cgcaagaaga tatattggct gcggtcttgg
     6001 gcgcttggcg ttcgtctgcg cttttctcgg cttctgactt ttcgagcaaa gatgatgtgg
     6061 tgatgctcta tggcgaagag aagttgcctc agtttgaccg ggcgaagaag aagtgggaga
     6121 tcaaacccaa tgcttccggc tacaaaccga aatgggggcg tagcggtgcc ggtaaccttt
     6181 tcctcaacta catctggtcg atggaagtgt ataacgacaa attatatatc ggaacgatgg
     6241 atatgtcaga cctgatagag ccggcgttga attcttcgga attttctttg ggtggcatga
     6301 actcttcatt ggtgctgaac atgctcaaag tcgataagaa acaatatggc tatgactgcc
     6361 tggtgatcga tgatccggag aaggagccgt ctttggtgac gaatgatggt tttggtaatc
     6421 cggcagccta cgggatacgt aatatgttgg tccatgacgg gcaactctat atcgggacgg
     6481 ccaatccgtt gaacctgcat gaacagggcg gctggagcct tttgacgttg actgaacggt
     6541 cagcgcctac agcaagtgct aaacaaccgg aagtggcgga tctgctctat cgtcagaccg
     6601 atagttatgt ggagatttct tcattgaaag gtgagtcgat tgaatcggtt acactggtcg
     6661 atatggccgg tcgggtcctc cggaaagaaa agggagattc tcctacagca gtcttggtta
     6721 cggacggatt gccgggcgga gtttatgtgg ttacggtgcg gacgaacgct gttacgaaaa
     6781 gtttcaaaat aaaagtgaga taatcaatat ttattattaa ttaaattgtt taacacatga
     6841 aaaaaagtac tcttagaaaa ggaggcgtag tccttcttgg tgctatgacc ttgttcggca
     6901 cgggtgttct ttcttgggcg aatattacgg aagctgtgaa tccgcctatt gaaaaagcac
     6961 agccggggtg gacaaaggtg acaaatggta aattcggtac ggagtcgaca gatttggaca
     7021 agaatcttcg cgactacgtg aagatggatc tgactcaggc agctaaaccg agccatgaca
     7081 atgttgctcg ttactgttca acgttcgatt tcagcaacct gggtgtcgat ctgcttccgg
     7141 gtttggcaat tagttttgct aatacaggcg ggaatgaggt tgtaaacggt cttttccagg
     7201 cttggtctta tgatgaggtt aagaaccatg aaccgatcaa gagttcttct gttttcaaag
     7261 ttgctttgaa tgaagaaggt actaaatacg gtttgggtat ttatccgaac tattcggcta
     7321 atgctcgcgt tgaattcgtt tacagcacaa gaggcctttc tgatgtcaac agaattcaag
     7381 tgaaattgga ttcatacggt gataaagccg aaatcaatgt ttctcgtact tacaaagtac
     7441 atgctactat ttacaatttg gatggaacta aggttaaaga cctgaatgag tatacttatg
     7501 tagctgacaa gaatcattta ggaaaaccgg aagaatgggc catccagact tctaatgtga
     7561 atgcaggcga aaatctgaaa gtcggagatt tggacaataa gatcattcgt gtgatcatca
     7621 cttctgaaaa ccctgttcag gatggtcaaa ctgacgttac tgaaccgttg ttggtaatca
     7681 gcgatgttca tatcgatttc ttgcgtccgg aagttacttt ggctgttgca gataatgaag
     7741 ttttggaagc tggtgccggc cgtactaccg attgcgatct gaagacattg gaaactacag
     7801 ttaagttctg gaatacattg gatatgacag aactgggtgt agctgctcgt ggtgatatct
     7861 atcctaacga aggcaatgag ttgtcagaag aattgcgcta tgaaggtgaa agacctgctt
     7921 tctatgaaat ctctgctgcc catccgttta gactgcatgg cattaaggtg tcaaacgtga
     7981 gtgatcctac caaggaagat aaattctttg attttgctga aatagcaagc aaaaacggta
     8041 aaatcggtaa agatgtaacg aaatttacaa caggcgcttt ggttggtcag gactctttga
     8101 ttacttatcg tattccgaga gaattcttcg ttgaagcaaa tggtgaaaaa tttgccaacg
     8161 aatataaggt tacaatgacc tatgctttcg agccgttgac agttggtaca ttcgatgatg
     8221 aatatatcaa ggctacaact tctgctcgca gcacagatac agccaaggtt gttctgaaag
     8281 gtaattctgt tcctgtatac aaagaagctg acgaactgac atttacaaaa tatcgtgaag
     8341 ttcagtacgc taacgctatt gaattcaaga accttccgaa atttgctgat gttgatgacg
     8401 gtttctattt gaacaatgat acaaaagccg atgaaaatgc aacagaacgt tatgacgatg
     8461 atgctgttca gatcggttgg agagttgtta caaaagataa cgtatacttt atcagacaag
     8521 aaggtgcaac tcatattttg cctgtaaaag ctactgctcc tgaatatgaa atttacaact
     8581 acgccgatat caattggaac ctgaatacat ctattgtatt tgaagatgct atcttccctg
     8641 acgaaccgct tgaaggtccg ctttcgatta tcgactgtac aggtaaactg gaaaagaacg
     8701 ttatttctgt tcacccggta ttccgttgcg tacgtaagga tattaacatc agcaatagcg
     8761 aatctctgaa tccgatcgaa aaattcgctt tggcagatga attgacttat ggagtcgctg
     8821 attacaaata taccggtgca gacctgaagg ctggtaagga tgaagctgta tatgaaggtc
     8881 cggttgtcgc taaatgtgct caggctttcg tatggtatcg tttcgaaggc gattcaactg
     8941 ctctgggtgg agctatgttg gctaaagcta tcgacgctat ggatatcaac actggccgtg
     9001 tagatgctta cttctctggt tacagaactg gtgcattgga cgaaactgcc atgagatctc
     9061 gtgaacatac aatccgcatt tttgccggtg aaaatgttga aaaagatgca aatggtatcg
     9121 ctacaatcaa agtcttcaaa gagaaattca atatcgattt gtgggcaaat gatgttactg
     9181 gagataagaa ctggttacct gcagaaggtt attcttacaa agatgacagc ttcgaacaga
     9241 cgactaatgg cttcttcttc acttacaatg ctaaacagca gtatgtaaaa gcaagctgga
     9301 gcgcaacaag caatgctaac gacgctgctt ctgcatggcg tggtcagaat gtaaccgata
     9361 cattgtatat caaagtcgat ctgagcactc ctgctatgca ggctgctttg aaagaagatg
     9421 gtatccctgt acaggttgtt tatcgtccgt ataacgaaag atatacattg ttggaaggtt
     9481 tgagagatct cttcagaggt gatattcctc tgtgggctaa ctcttggaac catgttgctc
     9541 agttcggtat cgttgtaggc aatgcttata atgagttcta tacaacaggt tctacttcta
     9601 agggcttgat cacaactatg actacagacc actcgattgc ttcttatgca aacttcgcag
     9661 actttgtaaa caatcgtttc ggtgatctgc ctaacggtca tatccacgga atctacaaag
     9721 acttctatgc taaagatcat ggttcttact atgttggttc tgaatgtctg aatggcatca
     9781 agagagatca taacttcatc gttgccggtt tgaacttgat caacaatgta gagttgtatg
     9841 cttacgaagc tgctccgggc gcattcaaac gtacggttct tcctatcttg ggttctgttg
     9901 ctgaagacgg atctttggtt ccgaatgaat atggtgaagc tttgttcatc gtttctactg
     9961 atttcgctcc gaaggctgct gacaaggcta aagctgaagt tgaaaacatc actgtaaacg
    10021 gtgatttggt tgctatgaac tacttgaagg atgaagttgt cctcaaaccg gttcagactg
    10081 caggacacga ttctgtattc gtttatgacc tggataagga aaatcatggt tacctgtttg
    10141 acggcaagtt gaatatcttc aaccactatg ctgcttacga agctgattct gtttctacag
    10201 ttatcaaggg tgacgttcgc gttcctgaat tgtggctgtc ttctgacaga gctggtaagg
    10261 acaagatcgc tgcttactcg ttcgacgaag tattggccgg tgaatcgaaa gacggcgtta
    10321 tctacgtaca gggtcgtgac ctgccgttga gcaaggatga tccaatgttg gatggcaatg
    10381 taatcgaagc tgttctgccg atcgtagccg atggcgttta tacaagtgat gaagaaatcg
    10441 acatctatac tgctgctaaa gacacgctga acgaagaagg tgctattact ggtactatcg
    10501 cttggccggt aactatcact gcaactccgg atgtagacga cttgtgcaac acagaaggtg
    10561 tattctctgt agacggtctg tgtgaaaact tgaaacagga attgtctctg actcatgctc
    10621 ctgttttggc aggcggtttc gctgttgacg ttatcaagac gaacggtggc cgtgccgaaa
    10681 tcaactggga atctgttcct ggtgctgact actatacagt tcagattggt aacactgttg
    10741 tagatccgat ttctgaaaat gtattcatct ctcaggtttt ggctgaaaac aactctatca
    10801 aggttacttt gaagaacggt accggtaagg atatcaacaa agatatcgct atcaactact
    10861 tcttggaact gacaggttac gacaagaacg gtaaagttgt tgttgctcct gaagtgatca
    10921 gccgcgaaga gatcaacccg gatgtatggg tatctgaaga actcgttgtt aagtcattcg
    10981 atgctgaatt gtcagaagat atcatctaca agattcgtct gtgcgaatac gacacgaacc
    11041 gtcagatcga cgtttatgaa ttcgacaaca cttattctca cctgtatcgt aagactgttg
    11101 acggcggtgt aatcttgatg aaccgcggta gcttcaatac ggctgactgg tcaactgtta
    11161 aggttgaata cccgactgcc gacttcaaag ctctcgctac atctgaaaag acaaccgata
    11221 ctaaagtcac tgtagtcaat atggctgcaa gcacaaacta cgaagtacgt gtaattgctc
    11281 acagcgattg tgaaaaggtt aacgcttctc gttctgcttt ggctgacatc catacttcaa
    11341 tcgacgaagg tggttctggt aacgtagcat tcgaaggtat cgaagctccg acagctaatg
    11401 aaactatcaa cgctgcaact gtaaaggttg ttgccggtaa gggtcaggtt gtcgttatga
    11461 acgctgccgg taagaaggtt gttgtaaaca acgtcttagg ccagacaatc gctaatacgg
    11521 ttatgacatc tgacaacgtt acaatcgctg ctcctcaggg tgtagttgta gtagctgttg
    11581 aaggtgaaaa ggctgtaaag gcaatcgtaa aataagaaga cgatttataa tcaaataatt
    11641 ctaaaatgta aggccgcgca gagtggaatc ctatacgccc tctaagtatc ctgagaaggt
    11701 gaacaagcgg tcaaatatta ataatactaa agtattgaaa taaagttcat gctgtgagta
    11761 tttctgcgaa gaaagaaaac ggaaaaaaac aagccccgga ggtgtcagtc atctccgggg
    11821 ctttgtctgt ttggtgatta tcggtttgct taccggagct tgatctcgtc tacaaacaag
    11881 aacgccgaat tacctgcgcc tccgtgccag gccggaagtt tgtcgctctt gatgatgatc
    11941 tcgacgtagc gggcttttac cggatcgaaa gatatttctt gcgggtaaag gccgtctggg
    12001 tcatttttgc ctaaagacgg gattgttttg gatgctactt ctttgaagtt ctgcccgtcg
    12061 tccgaaattt ttacggtaac gcctgccgcg cccatgatcc aatctccttt cacgacattc
    12121 gtgttgaaag aaatgtggct gaattcggcc ggttctttca ggtcgataac ggcatcgagg
    12181 tccttgcctt ggaaccccaa ccaacgtccg gtcttgtagt tatcgttgcc gctcaggcca
    12241 tcggtcagtt ccggtccacc gttgaagtca tatcctctgc tgggggccac cttcaaggtg
    12301 accggtttgg ctgttgcctt gttgaaatcg atcttttcag agaagatgcg gctgtttccg
    12361 gtcgggcgga cagcaatggc tttcacctct gcattttgtt tgatgcggag aggcgcttcg
    12421 tatttcgggg aggctgccgt cggttcgctg ccgtcgagcg tgtaatggat atcggcgttc
    12481 ccttcggttt cgagcgttac gacgatttcc cctttgtcac catcggtagc gaaggaggcg
    12541 cgaacgtcga agatgtgttt ggcgtaattg tagcccaaac ggttgtaaag ctcggtcatg
    12601 cggaccaggc gaggcaggaa tgccttgaag tctttcggtg cgtttgtcca ttgtatttcg
    12661 gccaatgcgt ccatacgagg caataccatg tattcgacct ggctgaatgt cgggatatat
    12721 tctgtccaga ggttcgcttg cacgccgatc acatatttcc ggtattcttc cggtattccg
    12781 gcagtcggtt cgaacgaata gacgcgttcc aacggcagat aaccgccgat ggcaagcggg
    12841 tcgtgttccg tgtcggtaga ctggtaatag tcgaaataga ggtaagagtt gggcgtcatg
    12901 atcacattat gtttctgttt ggcagcttcg ataccgccgt ttacgccacg ccagctcatc
    12961 accgttgcgt tcggagccag tccgccttcc aggatttcgt cccaaccgat gatatgccgt
    13021 cctttgcttt cgacgaattt ctccatgcgt tcgatgacat agctttgcag gcgttcttcg
    13081 gccgtgtgtt tgtcgttccc tttgagacct tccgccttga tgcgggcttg gcacttcggg
    13141 caacttttcc aacgcacttt cgggcattcg tcaccgccta catgtatata ttcggacggg
    13201 aagaggtcga tcacctcgcc gagcacgtct tcgaggaaga tcatggcttt ttcgttaccg
    13261 gcacagatca cctcgtcaga aacgccccac tgtgtccaca cttcgtacgg tccgcccgta
    13321 caacccagtt cggggtaggt cgtgatggct gccaattggt gtcccggaag gtctatttcg
    13381 gggatgatcg taatgaaacg ttcttgggca taagcgatca cgtcgcgaat ttcgtcctgc
    13441 gtgtaaaaca tgccttcgcc atacggcttg ccgtcatatt tgccggagtt gcgtccgatg
    13501 actgtctccc ggcgttgtgt ccctatccgg gtcagttccg gatatttctt gatctcgata
    13561 cgccagccct ggtcgtccgt cagatgccaa tggaaacggt tcatgttgtg cagggcaaga
    13621 atgtcgataa acttcttgac cgagtcggtc gggaagaaat ggcgggaaac atcgaggtgc
    13681 atgccgcgat acgggaaacg cggatagtcg ttgatgctga cagccggaag ttcgatggcc
    13741 ataccttcgg ccacggcggg gagcgccttg cgcaaggtct gcacgccata gaaaatgccg
    13801 gcgttggatg ctccggcgat ctcgatgccg ttctcgctga ccagcaggcg gtagccttcc
    13861 gggttccgga tgtcggaagc gatcgacaga tgaatgcctt tgtccgcgtt tcctgtgccc
    13921 actttcggtt catagcccgt ggcctctttg atgtaggagg cgaggaaacg ggcggtctgt
    13981 tccatctctg tatcaccttc cttataagag atcggggtag acggttttaa caggaacgga
    14041 gcgctgcctt gtgtcgccac ttcttgcgga agcgggatta tggcgtagtc gccttgtgct
    14101 tttttaccat ccgaacaagc cacggctccg gccagggctg tcaggataca tgcatacttc
    14161 gttagtttgt tcatgcgttt aaaatgttat aaagtgaaaa aatgatgatt cttatttggt
    14221 ccagtagtcc a
//
