LOCUS       c00006_gnlPro..        17254 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HMOBBPNF_6.
ACCESSION   c00006_gnlPro..
VERSION     c00006_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 12:41:12
            Original ID  :: gnl|Prokka|HMOBBPNF_6
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17254
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..276
                     /locus_tag="ctg6_1"
                     /transl_table=11
                     /translation="IDSKIAISEVDQKRIVIKDMGSGQINIGFTDAASITDTVEISLTD
                     EELAYLKSRVEFIDRNGMFSEFTMPTYVKILDEATKESASASTDTL"
     protocluster    1..17254
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4274:7254]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4275..7254
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17254
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17254
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             604..1275
                     /locus_tag="ctg6_2"
                     /transl_table=11
                     /translation="MEKSEELQIATSGKNMDIHRMELLPVVCLSVYKEIIKEMAELIED
                     KQIREIFCSLSLGKDLLCVSQITGISSKNLVSMYKRGIRQIHLKWKPYSELKRELDHIY
                     IKCRNNELLLTHSEEVSKKNFRYVKIVLKEQDIPTEYVDLLSTPLSKLDINSRTLRAFR
                     KYNIYQLEDLLRFIKYNGFEALYQMPGIGTKSIEQLYEKLKDKKILVDQDTCFLFPYLF
                     V"
     CDS             complement(1554..2912)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_3"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.5e-47, bitscore:
                     154.9, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTGIRFRAVPNGHEFTSLLLAVLNCDGKGKNIPDEGICARVRAL
                     NGPIKLTTYVSLTCTNCPDVVQALNVMATLNSCITHETVDGAINQKEVEAMKVQGVPSV
                     FADGRLINVGRSDLGELLSKLEAQYGINEGGVDNSVEKPVKNYDVLIVGGGPAGAASAI
                     YSARKGLNVAVIAERIGGQVKETVGIENLISVPQTTGQQLANDLLTHINDYLVDILEHR
                     RVDKVELDGSTKLLTTSTGERFSAPALIVATGASWRKLNVPGEADYIGKGVAFCPHCDG
                     PFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADQVLQEKAKSLPNVEVF
                     LHSQSLEVLGNGDKVTGLRVKDRKTDAERVIDLDGIFVQIGLAANSGVFRDVVETNKPG
                     EIVIDAHCRTNVPGIYAAGDVSTVPYKQIIIAMGEGAKAALSAFEDRMRGSIG"
     CDS             complement(3124..3690)
                     /locus_tag="ctg6_4"
                     /transl_table=11
                     /translation="MEPIINSQVPEFKVQAFQNGSFKTVSSEDIKGKWAIFFFYPADFT
                     FVCPTELVDMADKYGKFQEMGVEVYSVSTDSHFVHKAWHDASETIRKIKYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKIAEIHDNGIGRNADELLRKVEAAQFVASHP
                     NEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             3967..4272
                     /locus_tag="ctg6_5"
                     /transl_table=11
                     /translation="MRRASLYNTFSASLLLVCNACLSSCVSQIPLTKEKPVNNSTYQVE
                     YLFEHEGCKVYRFMDMGHYIYFTNCKGDVTSIESDSVRTVNRISRKPIIIKEQTLD"
     CDS             complement(4275..5006)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 73; E-value:
                     9.7e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_6"
                     /sec_met_domain="Radical_SAM (E-value: 3.7e-35, bitscore:
                     114.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LINMLGRIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWE
                     VKRETPYLLEPEALLAEVLRYKNFIAKGGVTVTGGEPLLQPEFLKEFFRLCRENGIHTA
                     LDTSGYICSGKALEVLEQVDLVLLDIKTIDAGLHPRLTAVKLDNTLRFLDELEKRGIPV
                     WIRHVIVPGLTDDDEALSKLAEYISSYNVVQKAELLPYHTMGAYKYEAQGLDYKLKGVE
                     PLSAERLANAKAIFMKHGVTV"
     CDS             complement(5014..7254)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_7"
                     /sec_met_domain="Gly_radical (E-value: 1.6e-45, bitscore:
                     146.7, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.9e-281, bitscore:
                     926.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENENWAQFKGETWKKEINVRDFIQNNYKPYNGDDTFLVPSSE
                     KTKKVWNKLTEMFKVEREKGVYDAETKLPQGIDTYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTDEMIAARRSAIITG
                     LPDAYGRGRIIGDYRRVPLYGTQILIEEKKRFQKRLDIQELTEEIIQSREEITEQIKAL
                     KAFEKMCAGYGFDVTRPAKDAREAVQFLYLAYLAAVKDQDGAAMSLGRTSTFLDIYIEK
                     DICEGKLTEEEAQELIDQFIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTKTSYRYLHTLYNLGPAPEPNLTVLWFNNAPDNWKNFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQYFGARANLAKCLLYAINGGRDEKSGVQVAPRFEPITS
                     EYLDYNEVMEKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMGLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVKVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVDITEKFM
                     EYLRQHQTYRKATPTQSILTITSNVVYGKKTGTTPDGRPGGTPFAPGANPMNGRDTKGA
                     VAALASVAKLPFQHAHDGISYTFAVSPATLGKERDIQINNLVSLLDGYFTPDGGQHLNV
                     NVFDRDLLLDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINSSL"
     CDS             complement(7681..10410)
                     /locus_tag="ctg6_8"
                     /transl_table=11
                     /translation="MNKRFSTLLAAALVAGSFSSAFAQLEGRNVEWKDAQASRAYYLAG
                     VHFVSPTDYLQAFSLQGLVNGADITAANPVAAAQWTVETKKVGTVTHYAFKNIEGEQYL
                     AFEKKDGAYALAAKKEANDETKSFRWFTVAANGNLQAVLSDEKEPYFLGLKNDGTADWS
                     LALLQSSEHHTDGSTSVIKKKVALYEIYNDQITAEAFASKFGENFTIEFPETLDDMDVF
                     ENVSVEKIANDNLGFKLVDNKGTKDTKDDEYVVLANERVSNSELAANAIGYRYAKMTAK
                     AIKDKKIDDKNTVFYAEENETNIGDGKYALVQKVKVGDLDNKDVTFGKVTNDETTRQLA
                     SVEYDCHSTFMGVTVGKGTRVANTEVANERMLIVNVTAKVADKKNSSALGLKNDFTGAR
                     WYDKVSEADFDQPQGQWLVAAGSAANTIKLINVQKPGFVQDNIRLYEAEGENTYTVFAS
                     DLGLSGLETITLTKVEDYDKLNGYYSTLSDINQKFAFVTTGEYANEEAGSDLYLKAGVE
                     GDVVTVVPHAGSEWELIRNEKAQAVTANYKYYDGEKWVELNGKGNEEKGILPADTVRLA
                     YSYAINADELGLGTAWKMAKDDIEFFLKENGKGTYAIVYGATADEVKEYGVINGSEELV
                     AETTDFTNSTPFEIIDLDAAPSLAADSKHMTFEATNSIGFIASDENNNAVLAKETAALW
                     VDSVNAEGYATPKFFISYAGKMMTTAKKFKEIVDKAYANDEISKKEYAELTADENLYYK
                     SVERIKFVDAERLSGEDTLVIADEKYTGKDIEDFKFKVTENEDGDYVLKANGNYVYVIN
                     GNLVYGTDAKEAEAFVIEVTSAPTANEGIATSEVKVIAGEGNVTISGAAGKKVVISNIL
                     GQVVANTVVSSDNATIAAPAGVVVVAVEGEAAVKAIVK"
     CDS             11081..11524
                     /locus_tag="ctg6_9"
                     /transl_table=11
                     /translation="MEYMKEKIDSSDIPTSYLLCMKQDCPKATTCLRRIAEQQIGDEVK
                     LWHVISPKYQEKQTDRCAYFRPADKLPYALGFIGMLDRMPYKLMQEAICKLMRRFGRRT
                     YYRVRKGERPLSPDEQKSMLNILKQCGINDPGKFDAYFEAYDW"
     CDS             12113..13453
                     /locus_tag="ctg6_10"
                     /transl_table=11
                     /translation="MKRLTNLLAITLLTSCVTAFAQEQEETTTEKSAVEQSADIYAAGY
                     NKFRFGGYGEILANFMDYGINRFRGTDNGSKKDHRNSISIPRFVLAFDYKFNSQWVLGA
                     EIEFEAGGTGSAYEIENTENGEYEMEVEKGGEVALEQFHITRLIHPAFNVRAGHLIVPV
                     GLTNEHHEPINFFGTSRPEGETTILPSTWHENGIEVFGTFGRGYTRFNYQALVVAGLNA
                     NGFDRNTWVAGGKQGLFETDNFTSPGYVARLNYLGVPGLKIGGSFYYCHNTGANSDKPE
                     TYVKYGNIPLRIYTADLQYKNKYVTARANMIYGNLSKADDLSSVNNHQSGSSPYTQTTP
                     IAKRAVSYGGEVGFNLRAVCKDNMSVPVIYPFVRYEYYNPQEKGEGKHTMDLRNKVSMW
                     TAGANWYALPNLVVKADYTTRKIGGGKYNSENEFSLAIAYIGWFLSK"
     CDS             13490..14755
                     /locus_tag="ctg6_11"
                     /transl_table=11
                     /translation="MKKKNYFYLAALSLAMTFSMGACSDNNDPNPDGGGKDPVNLDYSS
                     ENASAWGNYMYNVAMLLNDDATMLYNSWVTDYVDEQGSHGPYATIFKDQTAGAYQSPLS
                     CIEEMIESGMWNIANEVGDAKIKDPYTKYTSGDKEGGLYAVESWYSWHSRDDYTNNIFS
                     IRNTYYGRIDDNDVSKVDGNLSAFNSYKDFDDEGDIAEHSLSKLIASTNPALDEEIKTL
                     IFASAKAIQAIPQPFRNNIDSEESVAAMNTCMELANLLLNEVKPYVNQTFGDPEYDDDL
                     DAIAEQFVDAVVLPTYKDLQEKNKLLLDAVNQFRQNPSNDNFEKACNLWITAREPWEKS
                     EAFLIGPVANLGLDPNMDSWPLDQNGIVQVLNSQNWDDLEWSGNFDEEDEAIGAAQSVR
                     GYHTLEYLLFKDGQPRTVDGAK"
     CDS             14791..14895
                     /locus_tag="ctg6_12"
                     /transl_table=11
                     /translation="MTNLETADKCPLFQGFRVITQCDSRYSEINSENQ"
     CDS             14902..16335
                     /locus_tag="ctg6_13"
                     /transl_table=11
                     /translation="MKQSYLLTSSLFLLFACAACEEDDKMDMDKIDVPNGYALSAGTST
                     IFLNSSVAYDTNADWITGANSIRFNNGDGLYDDVRTSNNGDGGGLGPVYAGYSCGSCHR
                     NAGRTKPTLWENGGSGNYGFSSMLVYISRRNGAFFRDYGRVLHDQAIYGVKPEGKLSVT
                     YDKQTFSFPDGETYELCKPNYTITEWYKDSIAPEDLFCTVRIPLRHVGMGQMMAIDRRE
                     IEALAAKSNYPEYGISGRCNYITEKGVTGVGLSGNKAQHLDLTVELGFSSDMGVTNSRY
                     PEEICEGQAQINQGSMMGLSYDQLDISTADMEDVDLYMQSLGVPARRNINDPQVILGEQ
                     KFYEAKCHLCHVTTLHTQAGGSTLLNGTRLPWLGGQTIHPYSDFLLHDMGSEIMGVGLN
                     DNYVSGLARGNEWRTTPLWGIGLQEKVNGHTYFLHDGRARNLTEAIMWHGGEGEASKNL
                     FKQMSKEEREAVIAFLNSL"
ORIGIN
        1 atagacagta agatagcgat ctcggaggtt gatcagaagc gtatcgttat caaggatatg
       61 gggagtggtc aaatcaacat cggatttacc gatgcggctt ctatcaccga tacggttgaa
      121 atctcattga cggatgaaga attagcctat ctcaaaagtc gtgttgaatt tattgatcga
      181 aacggcatgt tttcagagtt cactatgccc acatacgtga agatcttgga tgaagcaacg
      241 aaagagagtg cttcagcatc taccgataca ctctgactct accaaggcga acggaaaggt
      301 tcgccttgct tctttataga ccctcccttt taaaagactt tcaaatggtc ttcaaatcaa
      361 ttagactata aaggctatca acaaatcgtt tgccgttttt tttgattttt cgtttttgaa
      421 atcttgattt ttggttttgc ggattatata atgatccgga attttctttt aaggaaatag
      481 ccgaagaact gggcttcagt tcttcgccac atctaacaac atattgtcaa aggatgtttg
      541 ggatgacccc cagccaatta agagaaaaaa ataaagataa atggattaaa taaattgttt
      601 tttatggaaa aatcggaaga gcttcaaata gcaacttcag gaaagaatat ggatatacac
      661 cgtatggagc tattgccagt ggtatgctta tcggtttaca aagagattat aaaagagatg
      721 gcagaattga ttgaggacaa acagatacgg gaaatatttt gttcactatc tttaggaaaa
      781 gatcttctat gtgtttcaca gataacaggc atttcgtcca agaatctggt ttccatgtat
      841 aagaggggga tccgacagat ccatttgaag tggaaacctt attcagaatt aaaacgagaa
      901 ctagatcaca tatatatcaa atgccgaaat aatgaattgc ttttgacaca ttctgaagag
      961 gtttcaaaaa agaatttcag gtatgtaaag attgttttga aagagcagga tattccaacg
     1021 gaatatgtgg atctattaag taccccttta agtaaactgg atataaactc caggacttta
     1081 cgtgcattca gaaaatataa tatctaccaa ttggaagatc ttttaaggtt cattaaatat
     1141 aacggatttg aagctttata ccaaatgcct ggcataggca ctaaatctat tgaacaatta
     1201 tatgaaaagc tgaaggataa gaaaatttta gtagatcaag acacttgttt tttattccct
     1261 tatctttttg tatagatatg tcacactgat atacaataca tacattttgt aggtagacaa
     1321 tgcacagtct ttcgtagtat cggataagtc ggcatcggaa acaaaaaact tgtgaaatag
     1381 ttactattat ctctaatctt ctcttcagcc cttccaagca ccgttacaac tacttaccag
     1441 ctattggtgt aatcaactct ggttatgact cgaaaaagga tactcacaga agaaggtatt
     1501 aggcatagag aacggaaaca tatcctcccc tcattcatag caaatactaa atattaaccg
     1561 attgaacctc tcatgcggtc ttcaaaagca gatagagccg cttttgcccc ttctcccatt
     1621 gctatgatta tctgtttata gggtacggtc gagacgtcgc ccgccgcata gatgccggga
     1681 acattcgtcc gacaatgcgc atcgattaca atctcacccg gtttgttcgt ttcgacaaca
     1741 tcgcggaaaa cgccactgtt ggctgccaag ccgatttgga caaagattcc gtccaggtcg
     1801 atcacccgct ccgcatccgt cttacgatct tttacacgaa gacctgtcac cttatcgcca
     1861 ttaccgagca cttccaaaga ttgggaatgc aagaaaactt ccacattcgg caagctcttt
     1921 gctttttcct gcaacacttg gtcggctttc agttcgtcca taaattccag aaccgtcact
     1981 ttcgaacaaa tgccagccaa atctatagct gcttcgatac ccgaatttcc accgccgaca
     2041 accgctacgt gcttaccttt atagaacgga ccatcgcagt gagggcaaaa agcgacacct
     2101 tttccgatat agtccgcttc gcccggaaca ttcaacttgc gccagcttgc acctgtcgcc
     2161 acgataaggg caggagcaga aaaacgttca ccggtagaag tggtcagaag ttttgtcgat
     2221 ccatccagtt cgactttatc cacacggcga tgctccagta tatcgaccag atagtcgttg
     2281 atatgtgtca gaaggtcgtt cgccaactgc tgtccggtag tctgaggaac ggaaatcagg
     2341 ttctcgatgc cgaccgtttc tttgacctgt cctccgatac gttcggctat cactgcgaca
     2401 ttcaagcctt tacgtgccga gtagatagca gaagctgcac cggcaggtcc acctcccact
     2461 attaacacat catagttctt aacaggtttt tcaacagagt tatcaacacc cccttcatta
     2521 attccgtatt gggcttcgag cttggaaagc aattctccca aatcactacg ccccacattg
     2581 atcagcctgc catctgcaaa aacagaaggg actccctgta ctttcatggc ctcaacttct
     2641 ttttggttga tagcaccatc caccgtttcg tgagtgatac agctgttgag agtagccatg
     2701 acattgagtg cctgcaccac atccggacaa ttggtgcaag taagagacac ataagtcgtc
     2761 agcttgatcg ggccgttcaa agctctgaca cgggcacaga taccttcgtc cggtatattt
     2821 ttaccttttc catcgcaatt caggaccgct aacagcaaag aagtaaactc atgtccgtta
     2881 ggtactgcac gaaaccggat accggtaggc ataccgtctt ttacaattgt aaactgaagt
     2941 ccttcgccat ccgcaacgct gcatgacaaa tgatccgagc atgatgccac atcaccaagc
     3001 aggtctatta gctcctgacg gctttcgtga tcgggagcga cttgtatatc aaatacatat
     3061 tgggatacca gtccggagaa aatacccgaa agttggtctt tcattgctga gtctaacata
     3121 actttagatc ttaccaacca agtcgatact cggcttcaag gttgcttcgc cttttttcca
     3181 ctttgcagga caaacttcgt tcgggtgaga agcaacgaac tgggcagctt cgactttacg
     3241 aagcaattcg tctgcattac ggccgatacc gttatcgtgg atttcggcaa tcttgatctt
     3301 tccctcggga tttaccagga acgtaccgcg ataagccatc ccctcttctt caatcatcac
     3361 accgaacgca cggcttaaag cccctgtcgg gtctgccagc atcggatatt tgatcttacg
     3421 gatcgtttcg gaagcatcat gccatgcttt gtgtacaaag tgcgagtctg tacttacgga
     3481 atatacttcg acacccattt cctgaaattt gccgtacttg tcagccatat cgaccaattc
     3541 ggtcggacat acgaacgtaa agtcggcagg atagaagaaa aagatagccc atttgccctt
     3601 gatatcttcg ctacttactg tcttgaaact accattctga aaagcctgta ctttgaattc
     3661 gggtacttgt gaattgataa ttggttccat gatttttact atttaatttg ttactactat
     3721 tttttgttta ccctacaaag gtaaatcgta agatactgat tgaaagaatt tttcaaattg
     3781 ataattttta tctgccgata gacggatttc tatctgcaag catacttatc tactatgaca
     3841 ataggaagca aagtaatgtt ttccggaaca ataaaaatat acctaattgt aggtaaaata
     3901 cctttcgatc ataccatgtg attctttaat tgttaacttt ggatgttaac ttaaaaatat
     3961 tcgaagatga gaagagctag tttgtataat acattttcag caagtctatt gctcgtttgc
     4021 aacgcatgtc tttcttcatg tgtctcacaa atacccctta caaaggaaaa accggtaaac
     4081 aattccactt atcaagtcga atatctgttc gaacacgaag ggtgtaaggt ctatcgtttc
     4141 atggatatgg gacattacat ctatttcacc aactgcaagg gagatgttac cagtattgaa
     4201 agcgacagcg tccgcacagt caaccggatc agccgtaaac cgatcatcat caaagagcag
     4261 acactcgatt aggtttatac ggttaccccg tgtttcataa agatcgcttt cgcattggcc
     4321 agacgttctg ctgaaagcgg ttccacacct ttcagcttat agtccaggcc ttgcgcctca
     4381 tatttgtaag ctcccattgt atgataaggc agaagttcgg ctttctggac cacgttatat
     4441 gaactgatat attcggccag cttgctcaag gcttcatcat cgtccgtcag gccgggcacg
     4501 atcacgtggc gaatccatac agggatgccg cgtttctcca gttcatcaag aaagcgtaaa
     4561 gtattatcga gttttacggc cgtcaaacgg ggatgaagac cggcgtcgat cgtcttgata
     4621 tctaacagaa ccagatcgac ctgttcgagc acctccaatg ctttaccgga acagatatag
     4681 ccggaagtgt ccaacgccgt atgaataccg ttctcacggc aaaggcggaa aaactcttta
     4741 aggaattcag gttgtaacaa aggctcgcca ccggtcacgg taacaccacc tttagcgata
     4801 aaattcttat agcgcagcac ttcggcaagc aacgcttcag gttccagcag ataaggcgtt
     4861 tcacgcttta cctcccaggt atccggattg tggcaataca gacaacgaag cggacatccc
     4921 tgcataaaaa cgacaaagcg aattccggga ccgtcaacgg tcccgaaact ctctaaagaa
     4981 tgtatacgcc ccaacatatt aatcaatgga caattataaa ctgctgttga tggtgcgcga
     5041 gatgacgtca agctgctgtt cgcgtgtcag cttcacgaag ttgacggcat agccagaaac
     5101 gcggatcgta agctgcgggt atttctccgg atgctccatt gcatctaaca acaagtccct
     5161 atcgaacacg ttcacattca gatgctggcc accgtcaggc gtaaaatagc catccaacag
     5221 gctcaccaaa ttatttatct gaatatcgcg ctccttaccc aacgtagccg gtgaaacggc
     5281 aaatgtatag gaaataccgt catgcgcatg ctgaaaaggc agtttggcta cagaagccaa
     5341 agcggcgaca gcccctttcg tatcgcgtcc gttcatcggg ttagctcccg gagcgaacgg
     5401 cgtaccaccc ggacggccgt cgggagtcgt tccggttttc tttccgtaga ccacgtttga
     5461 tgtgatcgtc aggatagatt gtgtcggagt tgccttgcgg tatgtctgat gctggcgcag
     5521 atattccata aacttctcag taatgtcgac agcaatactg tccgtgcggt cgtcattgtt
     5581 tccgaaaggt acatattcgc cttcgcgttc gaagtcgaca gccaaaccac gttcgtcacg
     5641 gatcactttc actttcgtat cacggatggc agccagcgag tcggcaacga tagaaaggcc
     5701 ggcgataccg gttgcgcgga tacgttccac atctccgtca tgaagcccca tctcgaatgc
     5761 ttcatacgca tatttgtcgt gcatgtagtg aatgatcttc agtgcattga catagacttt
     5821 tgccaaccag cgcatcatct gctcgtattt ctccatcact tcgttgtaat ccagatactc
     5881 gctggtgatc ggttcgaaac ggggagccac ctgcacaccc gatttctcgt cacgtccgcc
     5941 attgatcgca tacaacaagc actttgccag gttggcacga gctccgaaat actgcatctg
     6001 cttaccgatc ttcatcggag acacacagca ggcgataccg taatcatcgc catagtccgg
     6061 acgcatcaga tcgtcgttct cgtactggat ggcagaggta tcgatcgata cttttgcgca
     6121 gaagtttttc cagttatccg gagcattgtt gaaccaaagc accgtcaggt tgggttcggg
     6181 tgccgggccg aggttataca aggtatgcag ataacggtaa gatgtctttg tcaccagcga
     6241 acggccgtca acaccttgtc cgcccagcga ttcagtcacc caaacagggt cgccggagaa
     6301 caggtcgttg tattccggag tacgcaggaa acggacaata cgcagtttga taataaactg
     6361 gtcgatcaat tcctgtgcct cttcttccgt cagcttgcct tcgcaaatat ctttttcgat
     6421 atagatatcg aggaaagtag aagtacgtcc gagagacatg gctgctccat cctgatcctt
     6481 tacggctgcc aggtaagcca gatacaagaa ctgcacggct tcgcgggcat cctttgccgg
     6541 acgtgtcaca tcgaaaccat aaccggcaca cattttctca aatgctttca gcgctttgat
     6601 ctgctccgtt atctcctcac ggctctgaat gatttcttct gtcagttcct gtatatcgag
     6661 acgtttctgg aaacgtttct tttcttcgat caggatctga gttccgtaca gaggtacacg
     6721 acggtaatca ccgatgatac gtccgcgtcc gtaggcatca ggcaacccgg taatgatggc
     6781 ggaacgacgt gccgcaatca tctcgtctgt ataggctgaa aaaacgcctt cgttgtgcgt
     6841 ctttctgtat ttggtgaaga tctcttttgt catcgggtcc agatgataac cataggcttc
     6901 cagactgttt tcgaccatgc ggataccgcc tttcgggaag ataccgcgtt tcaacggggc
     6961 atctgtctgc aagccgacga ttacttcgtt ttccttatcg atgtaaccgg gtccgtatgt
     7021 gtcaatcccc tggggaagct tcgtttcggc atcatatact cctttctccc tttcaacctt
     7081 aaacatctcg gttagtttgt tccacacttt cttcgttttc tccgaagagg gtacgaggaa
     7141 cgtatcgtct ccgttataag gtttgtaatt gttctggata aagtctctta cattgatctc
     7201 ctttttccag gtttctcctt tgaactgcgc ccagttctcg ttttcaaact tcataagctt
     7261 atcttgtcta tttcggttta ggcacgcaaa gatacgtctt ttccccctat ctgaaaagga
     7321 ttgtaaagga cgaggaatgt taaaccggag aaaataccta caaataggga taaggggaat
     7381 aaaaacgaag ccccggcagt acgaataccg ccggggcctg ttttttgtct gccgtccggt
     7441 cttcacagag ggaaaagcag tagaactttt aatttcatta ctttagtatt attaatatta
     7501 aatccaaccg ctcgttcgcc tgtcgcaggg taattgaaac cgtagatcaa gaaaacctct
     7561 tacatacggt ttcacgcagg ttgtctagaa ttatttgatt ataaaatgtc attgtgcctg
     7621 tgtaagggtg gttcgctaac cacccttacg atagacagta ttgtttttta gtatcaatcg
     7681 ttacttaacg atagctttta cagcagcttc gccttcaaca gctacaacta ctacacctgc
     7741 cggagcagcg atagttgcgt tgtcagaaga aacgacagtg ttagctacta cctgacctaa
     7801 gatgttgctg ataacaactt tcttaccggc agcgcctgag attgttacgt taccttcgcc
     7861 agcgatcact ttcacttcag atgttgcgat gccttcgttg gctgtaggag cagaagttac
     7921 ttcgattaca aatgcttcag cttccttagc atctgtaccg taaaccaagt taccgttgat
     7981 tacatataca tagttaccat tagctttcag tacatagtca ccgtcttcgt tttcagtaac
     8041 tttgaacttg aagtcttcga tatccttgcc agtatacttt tcatcggcga taaccaaagt
     8101 gtcttcacca gacagacgtt cagcgtctac aaatttgata cgttctacac tcttgtagta
     8161 aagattttca tcagcagtaa gttctgcata ttctttcttg ctgatttcat cattagcata
     8221 agccttatca acaatttctt taaacttctt agcagttgtc atcatcttgc cagcgtaaga
     8281 aatgaagaac ttcggagttg cataaccttc agcatttaca gagtcaaccc acaaagcagc
     8341 tgtttcttta gccaatactg cgttgttatt ttcgtcagaa gcgatgaagc caatgctatt
     8401 agtagcttcg aatgtcatgt gcttgctgtc agcagccaaa gaaggagcag catccaagtc
     8461 tatgatttcg aacggagtag agttagtaaa gtcagttgtt tctgctacta attcctcaga
     8521 accattgatt acaccgtatt cttttacttc atcagcagta gcgccatata cgatagcgta
     8581 tgtaccttta ccattttctt tcaagaagaa ctcgatgtca tccttagcca tcttccaagc
     8641 tgttcccaaa cctaattcat cagcattgat tgcatatgaa taagccagac gaactgtatc
     8701 agccggcagg ataccttttt cttcattacc tttgccattc agttcaaccc atttttcacc
     8761 gtcataatat ttgtagttgg cagtaacagc ctgtgctttt tcgttacgga tcaattccca
     8821 ttcagaacca gcatgaggaa caacagttac aacatctcct tctacaccag ctttcaaata
     8881 cagatctgaa ccggcttctt cgttagcata ttcacctgtt gttacaaagg cgaacttctg
     8941 attgatgtca gacaatgtac tgtagtagcc gttcagcttg tcataatctt caactttcgt
     9001 caaagtgatt gtttcaagac cagacaaacc taaatcagaa gcaaatactg tgtaagtatt
     9061 ttcaccttct gcttcatata gacggatatt gtcttgtaca aaacccggtt tctgaacatt
     9121 gatcaactta attgtgttag cagctgaacc cgcagcaacc aaccactgcc cctgtggctg
     9181 atcgaagtca gcttcagaaa ctttatcata ccaacgtgcg ccagtgaaat cattcttcaa
     9241 ccccagtgca gaagaattct tcttgtctgc aactttggca gttacattta cgatcaacat
     9301 tctttcgttg gcaacttcag tattagcgac acgtgtaccc ttgcctactg taacccccat
     9361 gaaagtagaa tggcagtcat attcgacaga agccaactga cgagttgttt catcatttgt
     9421 cactttaccg aaagtcacat ctttgttgtc caggtcacca acttttactt tctgaactaa
     9481 tgcatattta ccatctccga tgtttgtttc gttctcttca gcatagaata cagtgttctt
     9541 gtcgtcaatt ttcttgtctt taatcgcttt agcagtcatt tttgcatagc gataaccgat
     9601 tgcgttggca gccaactctg agttggaaac acgttcgttt gctaaaacta catattcatc
     9661 gtcttttgta tcttttgtgc ctttgttgtc aaccaacttg aaacccaaat tatcattggc
     9721 gattttttct acgcttacat tttcaaacac atccatgtca tccaatgttt ccgggaactc
     9781 gattgtgaag ttttcgccaa acttgctcgc aaaagcttct gctgtaattt ggtcgttgta
     9841 gatttcgtag agagctacct tcttcttgat aacggaagta gatccatccg tatgatgctc
     9901 agaactttgt aataaagcca atgaccaatc tgctgtgcca tcgttcttca gtcctaaaaa
     9961 atacggttct ttttcatcag aaagcacagc ttgcaaattg ccgtttgctg caacagtaaa
    10021 ccaacgaaac gactttgttt catcgtttgc ctcttttttg gcagctaaag cataagctcc
    10081 atctttcttt tcaaaagcca gatactgttc tccttcaata tttttgaaag cataatgtgt
    10141 aacagttcca acctttttag tttcaacagt ccattgtgca gcagcaacag gatttgcagc
    10201 cgtaatatca gcaccattca ctaatccttg caaagaaaaa gcctgcaagt aatctgtcgg
    10261 actcacaaaa tgcacccctg ccaaataata agcgcggctt gcttgtgcat ccttccattc
    10321 aacattacgc ccctccaact gtgcgaaagc tgaactaaaa gaaccggcta ccaaagcggc
    10381 agccaaaaga gtagaaaatc tcttgttcat aatctaaaat gtttaattaa taataatatg
    10441 tatattgaat atcgttctta cttcctgttt aacaggtttt taccaaattc ctgtattttg
    10501 acgagagaaa acgtacgttt tttttagtca tttttgaggg gctttctgga gggtttgtgt
    10561 tggaaagctg gtttttcgta cttgttaagc tatctgattg ataagaaaga atatagaaaa
    10621 ggaaaaataa ttggaagaaa ggattgcagg ttcaaaaagt agttgtattt ttgtgcagtg
    10681 aaaatggcga aagaaaacgt acgttttttc gctatttttc ttcttatacc catatacttc
    10741 ttattagcaa tgacttacat tgaaaaaagt gcctaaagcc atataaaaaa agagctgttt
    10801 tcaaccgctc gccaaacttt tttacatctt catcaaaaca aagataatca atcacctata
    10861 agattaactc cctttattca cattggaggg gaaaaacggc aaaaacagca ggtttcgtaa
    10921 tttcatcttg gaaaagctcc cccttctgtt aaagatatac aaaatacgga gtattggttg
    10981 cttagctcaa taacagcttc aagacttgca aaaccttaca ttattatgta tctttacatc
    11041 aacgtccgtc acagacggat caaacaacta taatacatta atggaatata tgaaagaaaa
    11101 aatcgactcc tccgacatcc ccacctccta tctgctctgc atgaaacaag attgccccaa
    11161 agccactact tgcttgagga gaatcgcaga acaacagatc ggcgacgaag tcaaactgtg
    11221 gcacgtcatc agccctaaat accaagagaa gcaaaccgac cgatgtgctt atttccgccc
    11281 tgccgataaa ctgccctatg cgctcggttt catcgggatg ctggaccgga tgccctacaa
    11341 actgatgcag gaagccattt gcaagctgat gagacggttc ggacgcagga cttactaccg
    11401 cgtgcgaaaa ggcgaacgcc cgctctcgcc ggacgaacaa aaaagcatgt tgaacatact
    11461 gaaacagtgc ggtatcaacg atcccggaaa gttcgatgcc tacttcgagg catacgactg
    11521 gtaagttcac atgacgctac ttgcctacgt attggttgtg ccatacctat gtaacgaccg
    11581 tttcctcggc atgaaacggt tgtgccaagc ttatgtaaca ggcgtttcct actcaggaaa
    11641 cagttgtgcc aagccgatgt aattgttttg gcacagccgg agcagcaaac atacccttgc
    11701 gggaacaagt ccaagactcg acgccgaaca gattccggac agaagcgaat gggaaacgga
    11761 aacataaaaa agaagcctct cttcacagag aggcttcttt tttataccga aaataaccaa
    11821 taaaaacttt tcgatatagt taatcatctt atatgcttac ataattgaca aaaggttttg
    11881 atatagcgat tatactaata gtgttacttt cttaatgaca ttgcaaagat acgggtactt
    11941 cccacctcct acaataccta tatgtgagta aaaaaacgtc ttttactacc taatcaaggt
    12001 gatattcagg cgcaatacct acaaatgggt aacatcggaa cctttttacc tactaattgc
    12061 gattgcacac cgttgacagc ccctctaatt ttgccaaaaa ttaaaaaacg caatgaaaag
    12121 gttaactaat ttattagcaa tcactctact cacctcttgt gtaacggcat ttgcacagga
    12181 acaagaagaa acaacgacag aaaaatccgc agtggaacaa tccgcagaca tttatgcagc
    12241 cggatataac aagttccgct tcggcggata tggggagatc ctcgcaaact ttatggacta
    12301 cggcatcaac cgtttccggg gtacggacaa cggaagcaag aaagaccatc gcaattcgat
    12361 ctccataccc cgttttgtct tggccttcga ttacaaattc aattcccaat gggtattagg
    12421 agcagaaata gaatttgagg ctggaggtac gggaagtgcc tatgagatag aaaacacaga
    12481 aaacggagaa tacgaaatgg aagttgaaaa aggcggtgaa gttgctttgg aacaattcca
    12541 catcacacgt cttatccatc cggccttcaa tgtccgtgcc ggtcatttga tcgtcccggt
    12601 cggtttgacc aacgagcatc acgagccgat caacttcttc ggaacttctc gtccggaagg
    12661 cgaaacgacc atccttcctt ctacctggca cgaaaacggt atcgaagtgt tcggtacgtt
    12721 cggccgaggc tacacacgtt tcaactacca ggctttggtc gttgccggat tgaacgccaa
    12781 cgggttcgac cgcaatacat gggttgccgg cggcaagcag ggactattcg aaacagacaa
    12841 cttcacctca ccgggctatg tggcccgcct gaactattta ggagtaccgg gattgaaaat
    12901 aggcggttcc ttctactatt gccacaatac gggagccaat tccgacaaac cggaaacata
    12961 cgtcaaatat ggaaacatac ctttgcgcat ctatacggct gacctgcaat acaaaaacaa
    13021 atatgtcacc gcacgcgcaa acatgatata cggcaacctg agcaaagccg acgacctcag
    13081 cagtgtcaac aaccaccaaa gcggcagttc tccttataca cagacaaccc cgatcgccaa
    13141 acgtgcggtc agctacggtg gtgaagtggg gttcaacctg cgtgcggttt gtaaagacaa
    13201 tatgagcgta cccgtaatct atccgttcgt ccgctacgaa tactacaacc cacaggaaaa
    13261 aggcgaaggc aagcacacga tggatttacg caacaaagta agcatgtgga cagccggagc
    13321 caattggtat gctttaccta atcttgtcgt gaaagcagac tatacaacac gcaaaatcgg
    13381 aggcggcaaa tataacagcg aaaacgaatt cagcttggct atcgcctata tcggctggtt
    13441 cctcagcaaa taaaaacaat ataaacaaat taataactta tcaataaaaa tgaaaaagaa
    13501 aaattatttc tatctggcag ccttatcgct cgccatgaca ttctcgatgg gagcatgtag
    13561 cgacaacaac gaccccaatc cggatggtgg cggaaaagat ccggtcaacc tggattacag
    13621 ttctgaaaac gccagtgcat ggggtaacta tatgtataac gttgcaatgt tgctgaacga
    13681 cgatgcaacc atgctctaca attcttgggt aaccgactac gtcgatgagc agggttcaca
    13741 cggcccatat gccacgattt tcaaagacca gactgccgga gcttaccaaa gcccgctctc
    13801 gtgtatcgag gaaatgatcg aaagcggtat gtggaacatc gccaacgaag taggtgacgc
    13861 caagatcaag gacccgtata ccaaatatac cagcggtgac aaggaaggcg gtctctatgc
    13921 cgtcgaatca tggtatagct ggcattcgcg cgacgactat acgaacaata tcttctccat
    13981 ccgtaacaca tactacggcc gcatcgacga caacgacgtg tccaaagtag acggaaacct
    14041 gagtgcattc aactcttaca aagatttcga cgatgaagga gacatcgcag aacactcgct
    14101 ttcaaaactg atcgcttcaa ccaacccggc tctcgacgaa gaaatcaaaa cgctgatttt
    14161 cgcttctgca aaggcgatcc aggctattcc gcaaccgttc cgcaacaaca tcgacagcga
    14221 agagtccgtt gccgcaatga acacttgcat ggaactggcc aacctgttgt taaatgaagt
    14281 aaaaccgtat gtaaaccaaa cattcggcga tcctgaatac gacgatgacc ttgatgcaat
    14341 agccgaacag tttgtcgatg cggtcgttct tcctacttat aaagacttgc aggaaaagaa
    14401 caagcttttg ctggatgcgg taaaccagtt cagacaaaac ccaagcaacg acaacttcga
    14461 aaaggcctgc aatttatgga tcacggcacg cgaaccgtgg gaaaagagcg aagctttcct
    14521 tatcggtccg gtcgccaact taggtctgga ccccaacatg gacagctggc ctttggacca
    14581 gaacggtatc gtacaggtat tgaattcaca aaactgggat gacctggaat ggagcggaaa
    14641 ctttgacgaa gaagatgaag ccatcggagc cgcacagagc gtacgtggtt accatacatt
    14701 ggaatatctc ctattcaaag acgggcagcc ccgcactgtc gatggagcaa aataaacatg
    14761 cctctgagac ataaaacttg ataatagatc atgacaaacc ttgaaacagc agacaaatgc
    14821 ccgctgtttc agggtttcag agtaattaca caatgcgact cgcgttattc ggaaataaat
    14881 tcagaaaacc aataaaatga tatgaagcaa tcttacctgt taacatcctc gctattcctg
    14941 ctctttgcat gcgcagcttg tgaagaggac gataaaatgg atatggataa aatagatgtc
    15001 ccgaacggat atgcgctgtc agcagggact tcaacgattt tcctaaactc atcggtcgcc
    15061 tacgatacga acgccgactg gataacagga gccaactcga tccgtttcaa caacggcgac
    15121 ggtctctacg acgatgtacg caccagcaac aatggcgacg gaggcggtct cggacctgtt
    15181 tatgccggct attcctgcgg cagttgccat cgcaacgcag gaaggaccaa accgacattg
    15241 tgggaaaatg gcggatcggg caactacggt ttctcttcca tgctggtcta tatctcccgc
    15301 cgcaacggtg ctttcttccg cgactacgga cgtgtattgc acgaccaagc catctacggc
    15361 gtcaaaccgg aaggtaagtt gtccgtcaca tacgacaagc agactttttc cttccccgac
    15421 ggagagactt acgaactatg caaacccaat tacacgataa ccgaatggta taaagacagt
    15481 atcgccccgg aagatttgtt ctgcaccgta cgcatcccgt tacgccacgt cggtatggga
    15541 cagatgatgg caatcgaccg cagggaaatc gaagcgctcg ctgccaaaag caattatccg
    15601 gaatatggta tcagcggacg ttgcaactat atcaccgaga agggtgtcac cggtgtcggc
    15661 ctttcaggaa acaaggcaca gcatcttgac ctgaccgtcg aactgggctt ttcaagcgat
    15721 atgggcgtga caaacagccg ctatccggaa gagatttgcg aagggcaggc tcagatcaac
    15781 caaggcagca tgatgggact ctcgtacgac cagctcgaca tatcgaccgc cgatatggaa
    15841 gatgtggacc tttacatgca aagcctcggc gtaccggcac ggcgcaacat aaacgaccct
    15901 caggtcatct taggagaaca aaagttttac gaagcgaaat gccatctctg ccacgtcact
    15961 acgctgcaca cgcaagcggg cggttccaca ctgctcaacg gcacacgttt gccatggctc
    16021 ggcggacaga ccatacatcc ttattctgat ttcctactgc atgacatggg gtcggagatc
    16081 atgggagtcg ggttgaacga caattatgtc agcggcctgg cacgaggaaa cgaatggcgt
    16141 actacgccgc tttggggtat cgggctgcag gagaaagtca acggtcatac ctatttcctt
    16201 catgacggac gcgcccgcaa cctgaccgaa gccatcatgt ggcatggagg cgaaggggaa
    16261 gcctccaaaa atttattcaa acaaatgagc aaggaagagc gtgaggcagt gatcgcattc
    16321 ctcaactcct tataatttat ccataagaca aactaaaatg aaacaactga taatcacaat
    16381 tgcagcatta ttactattgc cgttggccgt catggcccaa tatgaggaag atacggaaaa
    16441 cggtgtcgta tcactaaacg gcaaagaagg ttttacaatc gctaccaaga agggggattt
    16501 cgttttcaaa ccttatatgt tggtacagac cagtgctaac atcaactact acgacgatga
    16561 agggctggac ccggcctaca atcaggacaa tatacacaac agcggtttct cgatccctta
    16621 tgccatcctc ggtttcacgg gcaaggcatt cgaccgggtg acattcaacc tctccatcaa
    16681 tgctgccgga aacggaggaa acatccttca acaggcttgg ttcgacgtag agataaaaaa
    16741 gagttttgcc atacgtgttg gcaagttcaa gactccgttc tcgcacgctt acctgactac
    16801 gctgggcgag acgttaatgc cgacactgcc gacatcgctc acctcatccg ttatcctgcc
    16861 ttattctctt aatgccgtga caccgaacat cggcatggga ttcgacctcg gagtggaagt
    16921 gcacggattg gtaaaggata agttcggcta cgaagttggg attttcaacg gaacgggaag
    16981 ctccgtcaac gtggcatcca aaacgttcag cgacgactgg catatcccgt cattgttgta
    17041 tgccggccgc atcacgtaca tgccgaaagg agttatgccg tccaaccagg gcagcccgaa
    17101 ccgtttgaag gaagataaga tgctgttcgg tctttccact tcattgaatg tggagagcga
    17161 aagcgaaagt acgaacgatt tccgggcagg agcagaattc gccatgttga agaatcgcct
    17221 gtatctcggc gctgaaatct attatatgaa tgta
//
