LOCUS       c00088_gnlPro..        14862 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PFINNGNM_88.
ACCESSION   c00088_gnlPro..
VERSION     c00088_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 19:02:34
            Original ID  :: gnl|Prokka|PFINNGNM_88
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14862
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14862
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1422:4862]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1423..4862
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14862
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14862
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(210..1163)
                     /locus_tag="ctg88_1"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSEISCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPAPGVDSVYKRSGFIHPLKTLRGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLKINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             1423..2097
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_2"
                     /sec_met_domain="SucD_FumR (E-value: 1.1e-65, bitscore:
                     212.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IGFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             2136..4079
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 8.7e-60, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 5.6e-38,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             4107..4862
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_4"
                     /sec_met_domain="Fer2_3 (E-value: 3.6e-26, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 1.1e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.1e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             4873..5058
                     /locus_tag="ctg88_5"
                     /transl_table=11
                     /translation="MYVYGKARRQWQRAFFMFVQTHKKAALPIIKVDAAFLLLSSETVS
                     RFPLCKDFVNLRSKIL"
     CDS             5055..5213
                     /locus_tag="ctg88_6"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(5186..6217)
                     /locus_tag="ctg88_7"
                     /transl_table=11
                     /translation="MKIGTIDLGERPIFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKVVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLDILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             6598..7857
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg88_8"
                     /sec_met_domain="Peptidase_U32 (E-value: 4.9e-69, bitscore:
                     223.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNN
                     FTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAM
                     NYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITG
                     PKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIEL
                     DIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNG
                     TFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDK
                     IGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEK
                     IRPSDRLYKMEKVQLEKVFE"
     CDS             7857..8264
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg88_9"
                     /sec_met_domain="HBT (E-value: 6.9e-09, bitscore: 27.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 1.1e-09, bitscore: 30.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             8261..9376
                     /locus_tag="ctg88_10"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYF
                     KGNTNLDATRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRIGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAGATSVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVL
                     EIPVHQLSMLLFELEINGKVKALPGNLYKLS"
     CDS             9401..9556
                     /locus_tag="ctg88_11"
                     /transl_table=11
                     /translation="MWEKKRNLYKQLKAVSRQPLTNFVNLKSNTIMKKPHCKDTLVKSV
                     CQAFCC"
     CDS             complement(9627..10523)
                     /locus_tag="ctg88_12"
                     /transl_table=11
                     /translation="MKMLSFILVLLLGGFMPAGNLLASDKEQNPHYITVKNSRDLQAYF
                     RYAPDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLMHDET
                     IDRTTTGKGKVSDYTYAELQQFNLVDRNGNVTAFKIPTLKECLEWSKGKTILNLDIKDV
                     PLEVMADFIETEKPVNVMYTVHNASQARYYLDRKPDAMFSCWCKNREEFDNYEKAGIPW
                     KQVMAYVGPKMKPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYRSEISTRPD
                     VIETDYPYLFQGLDLTK"
     CDS             11158..11487
                     /locus_tag="ctg88_13"
                     /transl_table=11
                     /translation="MRWIWQIEPCFIKDILAKYEEPKPPYTTLASIVKNLERKKYVKAK
                     RYGNTYEYRPLIPQEEYKRTFMGSVVNNYFENSYKEMVSFFAKEQKISTDELKEIIDMI
                     EKGRE"
     CDS             11508..13244
                     /locus_tag="ctg88_14"
                     /transl_table=11
                     /translation="MTPEFAYFLKVNVAFILLYAFYRLFFYKDTFFKLRRTILLAFFGV
                     SLLYPLMNIQDWIREQGPIVEVIQMYSAILPETTITPGNVPQTNWHDLLLPGISYLYWS
                     GVIALSFRFLVQLSSILLLAQRSEVTLIRNVRVHLLNKPAGPFSFFRLVFLHPDSHSEK
                     EIDEILVHECTHVSQWHSIDVIICELVCIICWVNPFVWLLKREVRHNLEYLADDTVLES
                     GYDSRSYQYHLLGLAHTNRSVTSLSNNFNMLHLKNRISMMNKKRSRSIGRTKYLIFIPI
                     VGALLILSNVDALARITDELTESTFADVLLPEAILPFPFVGDASPAEKREDYVLSEEGI
                     EAARRARNQVFTVVEVMPEFPGGQGALLKFLATNVRYPESAVKNGIEGRVSCSFVVGKD
                     GAISEAEVIRGVSPELNEEALRVINSMPVWSPGKQRGKAVNVKYTVPVTFRLSGGKKKA
                     SSRIVQRQIKEVDTSGRVFTVVQQMPEFPGGQASLLKYLATRIKYPAIAQENGIQGRVS
                     CSFVVDTDGSLKNIEVIRGIDPSLDREAVRVIREMPKWNPGVQNNMAVAVKYTVPVTFR
                     LQ"
     CDS             13278..14831
                     /locus_tag="ctg88_15"
                     /transl_table=11
                     /translation="MKCKFSLLLFLCVLSLWGQAQSLNLQELVNKKQFQEVVARADSLT
                     PADSADYATMSAIGQAYEGLLRYKEAYQCFSHCLKMDTNNVDALNAVARNAINFGRIAE
                     AKQCYRKVLGTDSMNFYANYQLARLYYQLGDYGRATEHYHILASIEGENPSILTGLADC
                     HIKRGTGPNTMIALSLYARALELNPENVRVASSLINTLLRMGDGQGALQVCDTALFYNP
                     DNSQIRQSKGMALYMTKDYKQADSVYTGLLADGDSSFLNLKYAGAARYMSGHALDGVEL
                     LEKAYEIDSTDVETVMLYGASLGKTYDRKRAYELFDLAETNMQPKKFLVNMLTTFRGDA
                     LERDGRWPEAEKLYYAAWKEDPTQLHFLYKISTQYWDVDPGLFQQEEKLQKTIFSRYTY
                     LTAYMKTDKSQKYLYNYRPFLEAVCEDAFFRNADEVTMLAPDGKKTKLAVSDLRALVAQ
                     LPQMPEDERLRREKMQEHIKKAREKEKELRKSGAKLDTLALSKEEKEKARKMLKDADLE
                     "
ORIGIN
        1 ccccgacacc cggatctata agagcgtaag atccgggtgt cgggggcgga tacatggggg
       61 tgttgggtaa gttttattac gtgtttctca ttgatttgta gctgtattta cataaaagag
      121 ccttggcttt gatgatatag gagaacaagc cctttttcct tttcttgttt accttgccct
      181 gcaaattgtc agtttgtttt agtagaaatt caatcacgtt cgaaatcgga cagcacttct
      241 gccgtagtag cgttgatgtt cttgtccaat acataaatgc ggtaagacag gctcagttct
      301 ttaccgggtt ccaatgtgaa tgccttctgc ttggtcggtg agaaattcca catgacgtca
      361 ccggcaggct tgttgactgt tttgtcccat acgcgtaaag gctcaggata gttcaggttg
      421 gaaggggagg caacgattag gatacaggcc ttttcgtttc cggctttccc ttggtagtag
      481 caccaacggg ctctcgaacc gtcagcttcg tcgcgggaaa ggccttccga ggtgagcatt
      541 tcggctgtct gatcgttcca gtcttcgcgc gtacggatgc atatgccgcc ataacggtaa
      601 gcttccatgg tgatcgggct ggggctggcg aggcggatag tggtatgata gtcgatgtaa
      661 taacctggta aggatgttgt cccgatgttg atcttcaggc gttcgttcat tgctactttt
      721 tctgcgggag aatcggggta gaccacatgg tccagtgtcg caacaaaacc gttgtcggat
      781 acgtgttcga agttgcggaa gcgaactgtt ccttgttttt tgtggagatt ccagaaatcg
      841 atctcgtttc cttcgaacgt ggttttcgtc caggcatacc acaaaccgaa atgatggtaa
      901 tggtcggcgg gagaacaatt ggtcatcact tcgcctctca atgtcttcaa aggatggatg
      961 aaaccgctgc gtttatagac cgagtcaacg ccaggggctg ggtaaaccgt ggtatagttg
     1021 taagagaaca acagtttatc tcctatctta tagtctaagg ttttccccgt gtcgacgacg
     1081 gaacaggata tttcggaagg ctgacaagag cctaagaaca gagaaatcaa aaaaacacca
     1141 atagaaaaaa tagcagtttt cataatatga caattaaata ataatcagtt atccggcaag
     1201 accttgcctg tatcggctac aaaaaaacga aattttttcg tttcgcacaa tccgtttgtg
     1261 atatctgatg caaataaaac cagccagcaa gcagcgttct aattgatgaa atatttcttt
     1321 aatcgtttgc gtgatatggg gatttagcat acctttgcac gataataacc atagattgga
     1381 ggaaatttct aaatacaatt aaataactta aattattatc ttatgtggtt acttaattct
     1441 tctatcggga agaagctgat aatgagtata tcaggtcttt ttctcattct gttcttggtg
     1501 ttccacttat gtatgaacat tgcggcagta ttttctggtg aagcgtataa cgtgatttgc
     1561 ggtttgctgg gttctaactg gtatgctttg ctcggtacat tggtgttggc tgcaggtgta
     1621 gtcgtgcact tcgtgtatgc tattatcttg actctgcaga atcgtaaggc tcgcggtaac
     1681 gaccgttatg ccatcaacgc tcgtccgaaa ggtgttgaat gggcttctca gaacatgttt
     1741 gttttgggtg tgatcgttat cctgttcatg gttctgcact ttactcagtt ctggtacaac
     1801 atgatgtttg ccgaactggc aggtattcat ggtgacattc atccgcagga tggtgcagcg
     1861 tttatcaatt tctacttcca gggcaatgtt gtgaatacgg tgttgtatct gattgggttc
     1921 gttgctctgt ggtttcacct gactcacggt ttctggtctg cgattcacac aattggctgg
     1981 aacaataccg tttggttaag ccgttgggaa tgtatctcta aatgggttgc cactattatt
     2041 tgtggcttat tcgctgttat cacagttatc ttctacctga acggtgtagg tgcttaattt
     2101 cggatattat tttttcaatt tgaaaataaa acattatgac tcaaatagat tctaaaattc
     2161 ctcaaggccc gttggctgag aagtggacaa attataaaaa tcaccagaaa ttggtgaatc
     2221 ccgcaaacaa acgtcgtttg gacataattg tagtaggtac tggtctggcg ggtgcttctg
     2281 ctgctgcctc tctggctgaa atgggattca atgtattgaa tttctgtatt caggactctc
     2341 cccgtcgtgc gcactctatc gctgcacagg gcggtatcaa tgcggcaaag aattatcaga
     2401 atgatggtga ctcggtttat cgtctgttct acgatacaat caaaggtggt gactaccgtg
     2461 cccgcgaagc aaacgtctat cgtctggctg aagtgtcaaa ctctattatc gaccagtgcg
     2521 tagcacaggg tgtaccattc gctcgcgaat atggcggtct gttggataac cgttcattcg
     2581 ggggtgctca ggtatcccgt acgttctatg cccgtggtca gaccggacag cagctgctgt
     2641 tgggtgctta ctctgcattg agccgtcaga ttggtttggg aaaggtgaag atgtacacac
     2701 gccatgaaat gctggatgtt gtgaaggttg acggacgtgc tcgcggtatt attgcccgta
     2761 atttgattac cggtaagatc gaacgttttg ccgctcacgc agtcgttgtt gcgacaggtg
     2821 gttatgtaaa tacattcttc ttgtctacta acgcgatggc gtctaacggt tctgctgcat
     2881 ggcagtgcta caagaaaggg gcttactttg ctaatccttg tatggtgcag atccacccga
     2941 cttgtgtgcc ggtgaaaggt gacttccagt ctaagctgac tttgatgtca gaatcactgc
     3001 gtaacgatgg tcgcatctgg gttccgaaga agctggaaga tgcgaaggca ttgcaggccg
     3061 gaacaaaaaa gggaaaggat attcctgaag cagatcgcga ctactatctg gaacgtcgtt
     3121 atccggcatt cggtaacttg gttcctcgtg atgtggcttc acgtgccgct aaagaacgtt
     3181 gtgatgccgg tttcggtgta aatagcacgg gcttggcggt attcctggat ttctccgacg
     3241 ctatcaaccg tctgggtaag gaagtggtta aacagaaata tggtaacctg ttcgatatgt
     3301 acgaagagat cacgaacgat gatccgtatg aaactccgat gatgatttat cctgcattgc
     3361 actactcaat gggtggtttg tgggtagact atgaattgat gacttctatt ccggggctgt
     3421 tcgcaatcgg tgaagccaac ttctctgacc acggcgctaa ccgtctgggt gcttctgctt
     3481 tgatgcaggg attggctgat ggttactttg tattgcctta cacgatccag aactatctgt
     3541 ctgaccagat ccaggttccg cgcttcagca ctgacctgcc tgaatttgtg gaagcagaaa
     3601 aggctattaa cgctcgtatc gcgaagttga tgaacgtgaa gggtaaagaa acagtcgatt
     3661 ctatccaccg taagctggga catatcatgt gggaacacgt cggtatggca cgcgacgcgg
     3721 aaggtttgaa agaggctatc cagatgttga aagacctgaa gaaggaattc tggagcaatg
     3781 tattcattcc gggtgaggcc aatagcttga acgtggaatt ggacaaggca ttgcgtttgg
     3841 ctgactttat cgaaatcggt gcattgatgg cacacgatgc gttagaccgc gcagaatctt
     3901 gtggtggcca cttccgtacg gaacatcaga ccgaagaagg cgaagctatg cgtcatgacg
     3961 ataagttcat gtacgtctct tgttgggaat accagggtga agacaaagac ccggttatgc
     4021 tgaaggaaga tttgaactat cagttcgttg ttcctcaaac acgtaactac aagaagtaat
     4081 aatcatcaat cacaaaaatt agaatcatgg ataaagatat aaaggtaaca cttaaagttt
     4141 ggcgtcagaa aggtccgaaa gataaaggac agtttgagac ttaccaaatc gacaaaatca
     4201 atcagagtgt ttctttcttg gaaatgttag acattttgaa tgaacgtttg gttagcgaag
     4261 gtaaagaacc tatcgtattc gaccacgact gccgtgaagg tatctgcggt atgtgttcat
     4321 tgtatgtaaa cggacatccg cacggaccgg caacaggtgc aacaacctgt cagctctata
     4381 tgcgccgttt caatgatggt gagacgatta cgatcgagcc gtggcgttct gccggtttcc
     4441 cggtaatccg cgacttgatg gtagaccgtt atgcttatga taagattatc caggcaggtg
     4501 gtttcgtttc tgtaaacaca ggtggggttc ctgatgctaa tgcaattcct atttctaagg
     4561 ctgatgcgga tttggctatg gatgctgctg cttgtatcgg ctgcggtgct tgtgctgctg
     4621 cttgtaagaa cggttcagct atgctgttcg tctctgcaaa ggttagccag ctggctcttt
     4681 tgcctcaggg taaggtggaa gctgctcgcc gtgcaaaagc aatggttgct aagatggatg
     4741 aactgggctt tggtaactgt acgaacactc gcgcttgcga aatggaatgt ccgaagaaca
     4801 tctccgttag caacatcgct cgcttgaacc gcgagttcat ctctgctaag ttacaagact
     4861 aatacattat atatgtatgt atatggaaaa gcccgtcgcc aatggcaacg ggctttcttt
     4921 atgttcgttc aaacccacaa aaaagccgca ctccctataa taaaagtgga tgcggctttt
     4981 ttgttgcttt ccagtgaaac agtctctcga ttccctctct gcaaagactt tgttaacctt
     5041 agatctaaaa tactatgaaa aaaactcact gcaaatataa agtatattta ctgaatacgc
     5101 aagagtttgt aattacattt tattgcaaat ttgctacttt ttgttttaaa attgacactg
     5161 tgtgcggatt tacactgtta ttatatcaac aatcgatcga ttctgacact tgagagtcgc
     5221 tttgaaatcc gtatcctgta tgaaatttgt cggggatgga atccagaatg tcgaataatg
     5281 cttccactgt ttccgcacgt agcatggcga cgcgtgtctg cttgaagtct gcaatacctt
     5341 taaacagcgg agttgcagcc aaatggcggc gaatgtggag aattccccgg cgctcatcca
     5401 aacgttccac gctttgttcc acctgctttt tcagtatgtc cagataccat gaaaaagatt
     5461 cggcaggcaa tgtctcgcct gtatccagat aatgcctcac ttctctgaaa atccaggggc
     5521 ggcctatgct gccccggcca atcataacgg catccacgcc atattgttcg aaacgttgtt
     5581 tgcagatttc ggcggaagtc acatcgccat tgccgatgat gggaatttgt atgcggggat
     5641 tgttttttac ttcaccgatc agtgtccagt ctgcctctcc tgtgtacatc tgtgcccggg
     5701 tacgtccgtg gatggaaagg gctgcgatac cgcaatcctg tagctgttcg gctaagtcta
     5761 cgatgatccg gttgtcggca tcccagccca agcgggtttt tacggtgaca gggatgttca
     5821 ccactttgac gacttcacgg gtgatgtcca gcatcagtgg aatattgcgc agcatgccgg
     5881 cgcctgctcc tttgcctgcc actcgtttga cagggcaacc gaaattgata tcgagaatgt
     5941 ccggatgagc ggcttcgcaa atttgcgcgg cttcgaccat tgtcggaaca tcacggccat
     6001 atatttgtat ggcgaccgga cgttcttcat ccgccacatt cagcttttgc tgtgttttat
     6061 ttacactgcg gatcagggcg tctgctgaaa cgaattcggt ataaaccata tcggcaccaa
     6121 aacgtttgca catcaaccgg aaagaaatat ctgtaacgtc ttccatcgga gctaagaaga
     6181 tggggcgttc gcctaaatct attgtaccta ttttcatatt tatattatca atgacgggga
     6241 caaaggtact gatttcctgc taaaaacagg gataaaagga tatctactaa aaaatgtagt
     6301 aattgatcaa taaaaagtac aaatgtcata ctgtcaatga tatagataaa atgataagct
     6361 gaaatcatga tagttgcatg atagtagtat gatagttaaa aatagaaact atcatgtctt
     6421 aaggtattga ataacagatt ctaaaggaca acaatgacag tatgatggtt gttttgcaaa
     6481 tctttataga aaatggtatt tgatcacgat tttgatgctc tgagaaacgg atacccatgc
     6541 aattcttctc ggatattatt cctacctttg cgaacgaacc agtaaatgta taagaacttg
     6601 aacgagaaag attttgaaat aatggcgcct gtcggttcgt acgaatcact gatggcggct
     6661 atccaagggg gagccgattc tatctatttc ggtatcgaag gattgaatat gcgttcgcgc
     6721 tcttccaata actttacgac agacgatttg cgcaagatcg ttgcgctttg tcgtgagcac
     6781 ggtattaaga gctatttgac cgtcaatacg gttatttatg gggaagacct gcctctgatg
     6841 cgcgagatta tcgatgcggc gaaggaggcg gaagtttcag cgatcattgc ggccgatgtg
     6901 gcagctatga actatgccaa cagcatcgga caggaggtgc atctttccac acagctcaac
     6961 atttccaatg cggaagcact gaaattctat gcccgttttg ccgatgttgt cgtcttggcg
     7021 cgtgagctga atttgaaaca ggtgcatgaa atctatcggc agatcgtcga ccagcagatt
     7081 acgggaccga aaggagaact gatccgtatc gaaatgtttg cccacggagc tctctgtatg
     7141 gccgtttccg gtaaatgtta cctgagcctg cacgaaatga acgcttccgc caaccgggga
     7201 gcttgcatgc agatttgtcg gcgtgcttat tcggtaaaag ataaagacag caatatcgaa
     7261 ctggatatcg aaaaccagta tattatgtcg cctaaagacc ttaagacaat tcatttcatg
     7321 aataagatga tggatgcagg tgtacgggta ttcaagatcg aaggacgtgc ccgcggtcct
     7381 gaatatgtcc gcctggtgac cgaatgctat aaggaagctg tgcgtgccta ttgcaatggc
     7441 acgttcgatg aaaagaaagt tgccgcttgg gacgaacgcc tgcgcagtgt gttcaaccga
     7501 ggattctggg acggctatta tttggggcaa cggttgggtg agtggagtag caaatatggc
     7561 tccggcgcga ctaagaagaa agtgtatgtt gccaaaggaa tcaaatattt cgacaagatc
     7621 ggcgtggcgg agttcgaaat ggaatccggt aacctgaaag tgggtgatga gatcctgatt
     7681 accggaccga caacgggtgc ggttatgcag acgatagaag aaatccgtgt ggacttgaag
     7741 ccggtggacg agaccgttaa aggtgaacgg ttctctctca aggtgaacga gaagattcgg
     7801 ccgtctgacc gattgtataa aatggaaaag gttcaacttg aaaaggtatt tgaataatga
     7861 aagagtatat ttttaaactg acagacaagg tccgtgacta cgaatgcgac ctgcaaggag
     7921 tggtcaacaa ctccaattat cagcattata tggaacatac tcggcatgaa ttcttggagt
     7981 cgcttggcga gaacttcgga aagatgcacg aaaaaggggt tgacggattt gtatcgcggg
     8041 tagaaatcca gtataagacc tcgctcaaga gcggcgacag ctatatctct tgcctcaatg
     8101 tctataaaaa aggagtcaag ctcgtattcg agcaggatat atatagggct tctgacaatg
     8161 cattggcgac gaaaggaatc gtcgagtcgg ttatcgttga gaacggaaag ttgacacgcg
     8221 gtgaatattt cgacgaaatg ctaaaaagaa tagaacatac atgactgaca aacggattta
     8281 ccaaatcggc cttactatga taaacggcgt gggagatatc ctggcgcgtc atctcctgca
     8341 ggctttggga gaagcagagg ctgtgtttac tgaaaagcaa cagttgttag gaaggatccc
     8401 tggtatcggc agcaatattg ctgccgaaat caaacgcccg gaaatcttgc aacgggcgga
     8461 aaaagagttg gcttttatcg agaaaaacaa tatttcctgt tattatctga ctgatacaga
     8521 ttatccggtg cgcttgagag aatgtccgga tgcccctata cttttctatt ttaagggaaa
     8581 tactaacctt gatgcgaccc gtatcatcag tattgtgggt actcgcaacg cgaccgaata
     8641 tggtcgggag cttaccgaat cccttataaa agacttggca aaagtgatcc cggacttgtt
     8701 ggtcgtgagt ggattggctt acggcatcga tatctgtgcc caccggaacg ctttgtacaa
     8761 ccgacttccg actgttgctg tgctggcgca tggcttggat cgtatctatc cttcctgcca
     8821 tcggaatacg gctgtcgaaa tgctggaatc gggcggtctg ttgaccgatt ttcccagcgg
     8881 tacagaacca gaccgtccaa atttcctccg gaggaaccgg attgtcgccg gaatctcgga
     8941 ttgtacgatc gtggttgaat cggcagaaaa aggaggctct ttggtaactg ccgatattgc
     9001 attctcttat ggccgggatg tctatagctt tccagggcgc atcggtgaca gccattccaa
     9061 aggatgcaac aatttgatcc gacaaaataa agccggcctg atcacttctg cggacgatct
     9121 gctctccgct ctttgttggg atatccaagc tggggctact tccgttcaaa cggagttgtt
     9181 tttcgccgag gcggaaacat tcacctcgga acaaaatccg gttttagcca ttatgcgaac
     9241 gcggaatgag attcatatca acgagcttgc ctcagtgttg gagataccgg tacatcaact
     9301 ctctatgcta ttgttcgaac tggaaataaa cgggaaggta aaagcgttgc cgggaaatct
     9361 ctataagctg tcctgaccgg ctttttcgta tacgatttgt atgtgggaga agaaacggaa
     9421 cctctataaa caattaaagg ctgtctcacg acaaccccta accaactttg ttaaccttaa
     9481 atctaatact attatgaaaa aaccacattg caaagatact ctcgtcaaga gcgtttgtca
     9541 agcattttgt tgctaatact tgttaatcag atgagcataa atagcaaaaa gattttaatc
     9601 ggctataaag agtcctttaa actgcgttat tttgttaaat cgagtccttg aaacaggtac
     9661 ggatagtccg tttcgatcac gtcgggacga gtgctgatct ctgaccggta accggcggtt
     9721 ttctctgttt ccgttttcgc gcgatcatgt gtcggagcaa cggaaatcat gcacatgact
     9781 ccgttacggt gcagagcgtc atacagtggt tgctgttcag gcttcatctt cgggcctaca
     9841 taagccatta cctgtttcca ggggatgccg gctttttcat aattatcgaa ttcttcccga
     9901 ttcttacacc agcaagaaaa cattgcatcc ggtttccggt cgagataata gcgggcttga
     9961 ctggcgttat gtaccgtgta catgacgtta acaggctttt ctgtttctat aaaatcagcc
    10021 ataacttcta aaggtacatc cttgatatcc aaattcagga ttgttttgcc tttgctccat
    10081 tccaggcatt cttttaaagt tggaattttg aaggctgtca cgttgccgtt tcggtccacc
    10141 agattgaatt gttgcagttc tgcataagtg taatctgaaa cctttccttt cccggtagtt
    10201 gtccggtcga tggtttcgtc gtgcatcaat acgattatcc cgtcttttgt caaacgcgga
    10261 tctatctcga aaaacgattc catataggac aaggtctttt cgaatgattc gatgcagttc
    10321 tccggatagc cgtctagcat tccaccacga tgtccactga ttacaatcgg gcgatcggga
    10381 gcataccgga aataggcttg tagatcccgg ctgttcttca cagtaatgta atgaggattt
    10441 tgttctttgt ctgaagccaa aagattcccg gcaggcataa acccccctaa aaggagtacc
    10501 aaaataaaag atagcatttt catgatattg tatttatata gattctttgt caattatgcg
    10561 gcttaaaagt aagacttttt tatcagtggc gtactataaa agcactataa aaacatgaaa
    10621 atatgacagg caacaaaatg tgcaaagaaa gaggcaggta tataaaaaat taaggattgt
    10681 catctcgaca acccctaacc aactttgtta accttaaatc taatactatt atgaaaaaac
    10741 cacaatgcaa aaatacacta gctaagcttg tttgtcaagc cttttacgga taatatatgt
    10801 taagctctaa tagctatttt gtcaaaaaat gttggttatt tataaactat acagattcca
    10861 tgtaaaaact gctaattcaa atacttttta tcgtcggaaa aagtgaaatc ccatgcttaa
    10921 aaagtgtccc cttggagtat ataaaatcat taattaatat aggggatgtt ttggtgtggc
    10981 tgcttataga taaattcctt tttggcgcat gcagcgaata gatgatggat tattaattgt
    11041 taatacaaat taacgcatta tttcttgcat atttacgatg tattcgtaga tttgcgatac
    11101 gatcgtaaaa aataatatag aaacatggaa agattaacaa gacaggaaga ggatgtaatg
    11161 cgctggatct ggcagatcga gccgtgtttt atcaaagaca tcctggcgaa gtatgaagag
    11221 cctaagcctc cttatacgac actcgcttct attgtgaaga atctggaacg taagaaatac
    11281 gtgaaagcga aacgttacgg aaatacttac gaatacaggc cgctgatccc acaggaggaa
    11341 tataaacgga cgtttatggg aagtgtggtg aacaactatt tcgagaactc ttacaaggaa
    11401 atggtctcct tttttgctaa agaacagaag atatcgaccg atgagttgaa agagattatc
    11461 gatatgattg aaaaaggacg agaataaact gttaaataca taatgccatg acaccggaat
    11521 ttgcctactt cttgaaggta aatgtagctt ttatactcct ttatgccttc taccggctgt
    11581 tcttttataa ggacaccttc tttaaactac gccgtaccat cttgttggca tttttcgggg
    11641 tgtcattgct ttatccgctg atgaatattc aggattggat ccgggagcag gggccgatag
    11701 tggaagtcat acaaatgtat tcagccattt tgcccgaaac gacaataacc cccggcaatg
    11761 ttccccaaac aaattggcat gatttgttac ttcccggtat ttcttatctt tattggagcg
    11821 gtgtaattgc cttatcgttc cgttttttag tgcagttgag cagcatcttg ttactggcac
    11881 agcggtcgga agtgactttg atccgtaacg tacgtgtaca tctgttgaat aaaccggccg
    11941 gtcctttttc ttttttccgg ctggtatttc tgcatcccga cagccattcc gagaaagaga
    12001 tcgatgagat tttggtacac gagtgtacgc atgttagcca gtggcattcg attgacgtga
    12061 ttatttgcga attggtttgt atcatctgtt gggtgaatcc gtttgtctgg ctgttgaaaa
    12121 gagaggtacg tcataatctg gaatatttgg cggatgatac ggtacttgaa tcgggctatg
    12181 acagtcgtag ctaccaatat caccttttgg ggttggcaca taccaataga tcggtgacct
    12241 ctttatctaa taactttaat atgctgcatc tgaaaaatcg gatcagcatg atgaataaga
    12301 aacgttcccg gagcataggt aggacgaaat acttgatttt tataccgatt gtgggcgcct
    12361 tactgatttt aagcaatgtc gatgcattgg cccggatcac ggacgaactg acggaaagca
    12421 cgtttgccga tgtcttgcta ccggaggcta tcttgccgtt cccttttgtc ggtgatgctt
    12481 ctcctgctga aaaacgtgag gactatgtgc tatcggagga aggaattgag gctgccagac
    12541 gtgcccgtaa ccaggtgttt accgttgtgg aggtaatgcc ggaattccct ggcggacagg
    12601 gtgctctgct gaaattcctg gcgacgaatg tcagataccc ggaatcggcc gttaaaaatg
    12661 gtatagaggg acgggttagc tgttctttcg ttgttggaaa agacggagct atctcggagg
    12721 cagaagtgat tcgtggggta agtccggaac tgaatgagga ggctttgcgt gtgataaact
    12781 ccatgccggt atggtcgccg ggaaaacagc ggggcaaagc ggttaatgtc aaatatacgg
    12841 taccggtaac tttccggctt tccggtggaa agaaaaaagc atcctctcgt atcgtgcaga
    12901 ggcagattaa agaagtcgat acgtctggtc gtgtctttac ggtagtgcaa cagatgccgg
    12961 aatttccggg tggacaggct tcgttgttga aatatctggc aacacgcata aaatatccgg
    13021 ctattgctca ggagaatgga atacaaggac gtgtctcttg ctctttcgtt gtcgacacgg
    13081 atggaagttt gaaaaatatt gaagtgatcc gtggaatcga tccttcgctg gacagggagg
    13141 ctgtccgggt gatccgggaa atgccgaaat ggaatcctgg cgtacaaaac aatatggctg
    13201 tagccgtaaa atatacggtt ccggttactt tccgtttgca gtaattgacc agaatcggtc
    13261 attaatacga taccattatg aaatgtaagt tttctctatt actgtttctt tgcgtactgt
    13321 ccctttgggg acaggcgcag agtcttaatc ttcaggaatt ggtcaataaa aaacaatttc
    13381 aggaagttgt agcacgtgcg gatagtctta ctcctgccga ttcagccgat tatgctacaa
    13441 tgtcggcaat cgggcaggcg tatgagggac tgttgcgcta taaggaggcc tatcagtgtt
    13501 tttctcattg cttgaagatg gatacgaaca atgtggatgc attgaacgcc gttgccagga
    13561 atgcgatcaa tttcggaagg atagcggaag ctaaacaatg ttatcgtaaa gtattgggaa
    13621 ccgacagcat gaatttctat gccaactatc agttggcgcg tctctattat cagttgggag
    13681 attatggtcg agcgacggaa cactatcata tacttgcttc catcgaaggt gaaaatcctt
    13741 ctatcctgac cgggctggct gattgccata ttaaaagagg gaccggtcct aatacgatga
    13801 tcgctctttc tttgtatgcc cgtgctttgg agctgaaccc ggaaaatgtg cgtgtggcat
    13861 cttctctgat aaatacgtta ttgcggatgg gggacggaca gggagctttg caggtgtgcg
    13921 ataccgcctt gttctataat ccggataaca gccagatacg gcagagtaaa gggatggctc
    13981 tctatatgac gaaagattat aagcaggctg attcagtcta taccggtcta ttggccgatg
    14041 gcgattcttc ttttttgaat cttaaatatg cgggggcggc ccgctatatg tccggtcatg
    14101 cacttgatgg ggtcgagctg ctggagaagg cctatgaaat agattcgacg gatgtggaaa
    14161 cagtcatgtt gtatggcgct tccctgggaa aaacatacga ccgtaaacga gcttatgagc
    14221 ttttcgatct ggcggaaacg aatatgcagc cgaaaaagtt cctagttaat atgttgacga
    14281 ccttccgagg tgatgccttg gaaagggacg gccgttggcc cgaagcggaa aagctgtatt
    14341 atgccgcatg gaaggaagac ccaacccagt tgcacttcct gtataagatc agtacacaat
    14401 actgggatgt cgatccggga ctctttcagc aggaggaaaa attgcaaaag acgattttca
    14461 gtagatacac ttacctgaca gcctatatga agacagacaa gtcgcaaaag tatctttata
    14521 attaccgccc tttcttggaa gcggtttgtg aagatgcctt tttccggaat gccgatgaag
    14581 tgacgatgtt ggctcccgat gggaagaaga cgaagttggc tgtctccgat ctgcgtgcct
    14641 tggtcgccca gttaccgcaa atgccggaag atgaacgttt gaggcgcgag aagatgcagg
    14701 aacatattaa aaaagccagg gaaaaagaaa aggaattgcg taaaagcggt gctaaactcg
    14761 atacgctcgc cctgagtaag gaagaaaaag agaaagcacg gaaaatgttg aaagacgccg
    14821 acttggaata gatagaatag ctgaacaata taatcgatat aa
//
