LOCUS       gnlProkkaAECBKBKC_6    21557 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AECBKBKC_6.
ACCESSION   gnlProkkaAECBKBKC_6
VERSION     gnlProkkaAECBKBKC_6
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 14:08:28
            Original ID  :: gnl|Prokka|AECBKBKC_6
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 67838
            Orig. end    :: 89395
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21557
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11557]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11557
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21557
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21557
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             845..2176
                     /locus_tag="ctg6_57"
                     /transl_table=11
                     /translation="MEENQHTEFKESWHDEYTRYISAFCNTEGGVLYIGIDDKGEVVGI
                     EQPKKLIEKLPNFIAQKTGIMPLIHLREKAGKEYLEIEVQPSAMPISVHGRYYTRSGSV
                     TSELQGNQLNMFLAAKMGLTWESVIEEDFSLEDIDTDTVERFKLLAKDRVPSIEQETDL
                     LALMERLNLIVGGRFKRAAVVLFGKNVQRYVLQARIKIGKFLTDTEVLTTDIVEGNLIQ
                     QVDRALDILRTKYLLSYISYEGIHRREKLVYPYEALREALLNSIIHREYFVSSEIQVRV
                     YEDKLVIGNEARLHDITVEDLSRPHPSRPHNKLIADVFYKAGFIESWGRGTQRIIDNCL
                     AEGLSAPVYEHKMGFLYLTFFHERINERINERINERINELSDMEREVYQILREEPTIRQ
                     IDLANRLDLTEQYIRKLIKKLKEHGWIERIGARKNGYWKIIEKS"
     CDS             2173..3435
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 121.7;
                     E-value: 6.9e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_58"
                     /sec_met_domain="Glycos_transf_1 (E-value: 2.2e-25,
                     bitscore: 82.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILILNTSELTGGAAVAANRLAKALGKSGVEVSMLVRDRKTDHV
                     KVFSVNNSWTSHRLNSFRFIWERLIIFICNFFSKKNLFQVSIANTGTDLSKHPLVQQAD
                     VIHLHWVNQGFLSLSDIKKLVNTGKPIVWTMHDLWPATAICHYPGGCEKYISNCYQCPM
                     LKRNPFFDLAASVFKEKGKIGLSKITFVGCSRWIMEEAQKGNWLRTACFTSIPNPIDVT
                     AFKRMEKRVARKRFDLPEGKFLLLFAAAKLSDTRKGAIFLIEACEKLKEKYQDRIEIVL
                     MGNSSEELISQFPFKVNTLGYISDQDSMISVYACADMFVIPSLEDNLPNTIMESMACGT
                     PCVGFETGGIPEMIDHLKNGYVAKYKDTNDLAVGIKWIIDNQETFRFSEACVRKVHDCY
                     RESVIAEKYIALYQSLCNKRK"
     CDS             3534..5396
                     /locus_tag="ctg6_59"
                     /transl_table=11
                     /translation="MDDQHKPEWIKVDEWDFVEYVDSLLRSQEAVDLEFKTARAGFPNS
                     VWETYSSFANTDGGTIVLGIKEKNGALFVEGLLPEQIVSYRQIICNQLNNPDCVNVNLL
                     TDKNIQEVDYRGKSLLLIYVPRASRSQRPVYLTRNPLNGHTYKRNNEGDYKCTDTEVRR
                     MIADADEEHPRDSRILCNYSMEDIDLDSLKQYRLLLSSRQPDHPWLTLDDMAFLRKLGG
                     YRQDRQTGQEGFTLAGILMFGRTESITDNECAPSYFPDYQEKMSVDENVRWTDRICMDG
                     TWEANLFQFYRRVYPKLSSVLPKPFRLENGVRLEDTTTHVALREAFVNTLVHCDYMEEG
                     NITIEQWKDRYVFKNPGTLLVSKAQYYAGGESICRNKSLQKMFMLIGFSEKAGSGVNKI
                     FMGWKNANWRPPFVEEQSHPDRVVLNLPMESLYPEEVLEELKRLFGREIERIPYDQFTV
                     LALCYSEKQVSNERLQYILNQHSSNITKLLKSMCNAGFLESIGNGRGTRYRLLFLEKDE
                     SKPQKDESKLKKDESKSQKDESKLEKDESKKYMRYEDLSRLILSVCEDYVALEIIAEAV
                     HREASYLINRVIPRMLEDGLLERLYPSSPKHPLQKYRVRQVGNL"
     CDS             5403..6170
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_60"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6e-30, bitscore:
                     97.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEMNQQPTFSIITITYNAERWLERTILSVLSQSYPNIEYILIDGA
                     SKDKTVEIIKQYESGIASWISEPDKGLYDAMNKGLKRATGDYVWFLNAGDTLYTADTVQ
                     RIVASLKKKVSLPDVIYGETQIVDAEGRSLGMRRLKAPEKLTWKSFRMGMLVCHQSFIS
                     KREIAPLYNTEYRLTADYDWCIQCLRRSKRIHNTRLTLSNFLEEGLSSVNRKASLKERY
                     EVMCKYYGKVSTILLHGWFAVRFYFAKWFKGRV"
     CDS             6194..8698
                     /locus_tag="ctg6_61"
                     /transl_table=11
                     /translation="MRSIMSKWGKHIAAIAVFLVLTVIYFSPAVFEGKVVRQGDTEKAI
                     GMGNSQMDEYEKTAQPGEFSAWSDAMFGGMPYVSGYGNPAPRFPGYLLVEKPLKALGYM
                     DAGMVFTGFVCFYILMCVMGVNWWLAIAGAIAFALASYNLIIIEAGHVTKAYVIAYMPL
                     TLAGMALLFKRKYLWGAVVFLLGVAFSIANTHLQITYYLLLLCFFVYLGYLFNKLKEKA
                     YKELGTVTAIMAGCVILAVLPNAQNMYAQWDLGQNSIRGATELTTTTPSGEKISSGLDK
                     DYAFAWSYGKGELLTLLVPNAYGGSSGGMLGPDSELYKELRAKGAQVGKEVQAPTYWGE
                     KTFTSGPVYFGALVCFLFVLGMFVIRNPMKWWLFGGSVFLILLALGRNFDSFNDFMFHY
                     LPMYNKFRTVEMALVIPGMVFPIIAIWGLKEVLSETVSDALLKKGLIAALAITGGISLI
                     LWLMPSMLLDFRSSFDAQYQLPDWYYNALLMDRASLASADALRSLVFILLGAALLFWFY
                     TSKDRKKVATFVGIGVAVLMLVDLWTVDKRYLNDSNFIRQKPTEVYKETVADQEIMKDK
                     DLSYRVLNLNNPFLETTTSYYHHSVGGYYAAKLRRYQELIDHRLQGELNSVIEAFQKAQ
                     IAEDLMGAFAACPSLNMLNTRYIIYNPEQPPLRNPFAFGNAWFVDKVEVVENADAEIAA
                     LNTINPLTTAVVDKRFADEVKGFTPQLDSTATITLDSYRPNKLVYTTKTNSEQLAVFSE
                     IYYQPGWEATIDGKPAPHFRADWILRAMLVPAGEHQIVFEFRPQGYITAAYITSFSSLI
                     ILLLLIGAIGYSIWRAKKDKTA"
     CDS             complement(8861..9988)
                     /locus_tag="ctg6_62"
                     /transl_table=11
                     /translation="MNKYITYLFLLLLSCGKPQDNNGIFTMDLSKDDLPKTTVSLDDYT
                     TKWTRIDLETTEDCLLDPSFNIYPTDHFIVAYSFNRILVFDHTGHFIREISHFGEGPDE
                     HGLLFNCTVNPTSEQLVFVEMGNTEEIIRYDLSSGKQLTAIPIVAKKQLCDLLFIKDST
                     LVCFPYAGNQKQMAYKQNLAGEWIGTPPIPISEPAGPYNPIPISLFQVDNQWIYKGIYE
                     DTLYLVNNLEPFARFSRKDISPSKTELEVQNSSFINHLFTSNGMSLFGYPQYQLKEVSE
                     GIFDLVLVDFRAFLFNHADKQILEIEKMNCPPLSIIYEQKNLNDLFMLISSRNPKKLVL
                     KVPAEFMGKEEDENPVLFISDLIYPKKKQPTRGKP"
     CDS             complement(10001..11557)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_63"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 9.3e-08,
                     bitscore: 25.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3e-15, bitscore: 49.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.8e-09, bitscore: 31.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.5e-08, bitscore:
                     27.9, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLEYKNSPVLGFILNSKYYLYDRYSNSIFTVPRIFFEYLDDLI
                     SLDTDEFTQKYHNIFSKEEIIDLFKTLDYCQNDKKLIKPNRIPKFTISSIYSNAKKVEK
                     KLKKELTFLCINITEECNLRCEYCIFSGKYTKSRRHNSNNQIEWNYIEKGVNLFLEHST
                     DSNIRKIGFYGGEPLLYFDIIRKTINYVRSKCDNAIFTITTNATLLKDKILSFFVENNV
                     EITISLDGPQNIHDKNRIFPNGVGSFNTVIKNIESIKRLHHDFFENNIKFSATLSPGKY
                     KIKDLIDFFTYDMFPTLKRADLPLSLNYINYEENKYLSEVKYLDWTKKTENEIFKLYKK
                     IHIKGINKTSEIPAVLRALPIHREMMYINLRSNIAFDEFKFFWPNGACIPGMRSIFLNS
                     KGIFLPCEKLNSETEFCIGDVSTGFDIKKISQLIADYSREIAPLCSNCWAFRFCGECWT
                     TAVKNGQISKDFRSQYCSYIKSYWARRLFLYTEIIEKNPKAFSYQGSIDYPEFMSHMIN
                     E"
     CDS             complement(11601..11774)
                     /locus_tag="ctg6_64"
                     /transl_table=11
                     /translation="MKQKTKKISWENFKDEIKVISAGQQKLLTGGGCACCICSPGNGNS
                     GLGGSTKASISH"
     CDS             complement(11795..12829)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_65"
                     /sec_met_domain="TIGR04085 (E-value: 1.6e-10, bitscore:
                     34.3, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 3.8e-07, bitscore: 23.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLKTAKKAVDFYFKNSNNCNHQISFIGGEPLLKFNLIKKIVEYI
                     KTFNNKVSFTIITNGSLLKEDILNYLIENMFHITISFDGEKEIQGLNRLSKDKKNSFDI
                     VYNNIRKIQLNNTRYFEQYVTINSVYSINITSSLSEFTNYLEAHFKNKFAINIQSSEIN
                     DEYTKFHNNFTKSFLSIYENIHIQGFENSSPPLFIISSDLHKKMMFFSRRSNNILQEET
                     RFIPIKSCLPYLNKIYISPTGDIFMCSDLYYIKGFNIGNIDKSIELNKLQDIMTQYTNF
                     RNKTCKKCWVYRFCDFCFYTLYASKERKGINKYCKIIKYDYAQVIKSYIKILKSNGSAF
                     DIYY"
     CDS             complement(12798..13178)
                     /locus_tag="ctg6_66"
                     /transl_table=11
                     /translation="MEDLFKTYKRNVALGINIDNLYYIYDRSSNNILEVSKYIYENLDY
                     LSLFESSIENIFINKKLSANYFNQWIPKLNTLKQNIDNTLSELTLNITETCNFRCKYCF
                     FNKKNRRIILQINVLKNSKKSS"
     CDS             complement(13190..14032)
                     /locus_tag="ctg6_67"
                     /transl_table=11
                     /translation="MRKQILIICIYIGELPWYFKFFLKSCSFNKDIDFLILCDQDMTSK
                     GISNNIKIKRYDLQDFKKDVHRSLNINTPIQNGYKLCDFKPAYGYIFSRYIEGYDFWGY
                     CDIDVIFGNIRAFITENILSKYEIITVRQDYLSGCFTLFKNEHKTNTLFMQSKNYLKVF
                     LSEKNFCFDETNFAFDEFAKSKDAYNINTEIESMTHVVLKMKDKGLLKPYFNLHILEGL
                     PGNMTWKKGTLLYKNKYEVLLYHLIFFKDFFKQYNKSTVPDEFIIEQTRITEISAFSY"
     CDS             complement(14176..15303)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 98.1;
                     E-value: 1.1e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_68"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.7e-18,
                     bitscore: 59.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFAILSPIYPYRGGIAQFSGMLYTELVKEGHEVKAFNFKRLYPD
                     ILFPGKTQYVEAGDRAIEIESVRVLDSVNPVSYFSTVNAIRSYAPDVLIISYWMSFFVP
                     GYAHVANRMKKHCKVITLIHNAIPHEPRFFDKPLASLLFKQCHGFIVMSDNVRYDLRKL
                     YPGAKYIQNPHPLYNHFGSKINKNEACRKLGIHPSKKNLLFFGLIRDYKGLDLLIEAMG
                     QLNEDYHLIIAGECYGSFEKYQALIDASPAKERIFVHCEYISDEEIPIYFSAADALVLP
                     YRSATQSGVVSVAYNYDLPMLSTPVGDFKNSIEKPGTGIVVPEISATALAQGIEELFTP
                     SQQATIPANISKEKAALSWETLTRKLLDFINSGFI"
     CDS             complement(15406..16779)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_69"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 2.8e-08, bitscore:
                     26.3, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLAEFGRKEIEIAEHEMPGLMALRQKYADQKPLKGARITGSLHM
                     TIQTAVLIETLVALGADVRWASCNIFSTQDHAAAAIAADGVPVFAWKGETLEEYWWCTD
                     MALRFPEGKGPHMIVDDGGDASLLIHMGYRAENDAETINRKGGNHEEQVILDTLNRILQ
                     EDNGRWHRTVAEMKGVSEETTTGVHRLYQMMEKGELLVPAINVNDSVTKSKFDNLYGCR
                     ESLADGIKRATDVMIAGKVVVVAGYGDVGKGCSHSMRSYGARVLVTEIDPICALQAAME
                     GFEVTTMEEAVKEGNIFVTTTGNCDIITIEHMTQMKDQAIVCNIGHFDNEIQVDKLVNY
                     PNIKHTNIKPQVDKYTFPNGNSIFLLAEGRLVNLGCATGHPSFVMSNSFTNQVLAQMDL
                     WQMAYEVGVYRLPKRLDEEVARLHLERIGVKLSTLSQKQADYIGVPVEGPYKADHYRY"
     CDS             complement(17010..17765)
                     /NRPS_PKS="Domain: PKS_KR (8-162). E-value: 2.2e-16. Score:
                     52.1. Matches aSDomain: nrpspksdomains_ctg6_70_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     227; E-value: 4.4e-69)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_70"
                     /sec_met_domain="adh_short (E-value: 3.4e-37, bitscore:
                     121.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 5.8e-31, bitscore:
                     101.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKTTEEKVALVTGSAMGIGLACAEAFAKAGYITVLADIREPREQ
                     VEKLVAEGHKAVAYRCDVSNTQAVKEMIDWIVATYGRLDAALNNAGIQTPQRPMAEITD
                     DEFDRTVAVDLKGVWNCMRYEILQMLKQGGGAIVNTSSQGGVTGFPGQAAYIACKHAVI
                     GLTRTAAIDYAAKNIRINAVCPGVIRTPMAEDLMRRDPSLEKELVRDIPAGRLGKPEEI
                     ANAVLWLCSPQASFVDGHALLVDGAFSIH"
     aSDomain        complement(17280..17741)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg6_70_PKS_KR.1"
                     /evalue="2.20E-16"
                     /label="ctg6_70_PKS_KR.1"
                     /locus_tag="ctg6_70"
                     /protein_end="162"
                     /protein_start="8"
                     /score="52.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALVTGSAMGIGLACAEAFAKAGYITVLADIREPREQVEKLVAEG
                     HKAVAYRCDVSNTQAVKEMIDWIVATYGRLDAALNNAGIQTPQRPMAEITDDEFDRTVA
                     VDLKGVWNCMRYEILQMLKQGGGAIVNTSSQGGVTGFPGQAAYIACKHAV"
     CDS_motif       complement(17295..17354)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_70_0001"
                     /evalue="2.10E-04"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg6_70"
                     /protein_end="157"
                     /protein_start="137"
                     /score="13.8"
                     /tool="antismash"
                     /translation="VNTSSQGGVTGFPGQAAYIA"
     CDS             complement(17875..18693)
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 53.5; E-value: 3.3e-16)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg6_71"
                     /transl_table=11
                     /translation="MDGINTLRYSDLFLAMYFDGGKSCLHRNHSHVLVYVYSGEMVIDE
                     KGQITRLHKGECAFIRKDFSVQMTKQAWNGEQFKAIFLMFTMKFLRDFYSKLDRNTLPK
                     DAKRDQVSLYKLPSNRPDIVSLFESMTPYFNSKIQPTDELLQLKMVEGVYVLLNTDKNL
                     YASIFDFTDPWKIDILEFMERNYMNDISMEEIANYTGRSLSTFKRDFKKCSALSPREWL
                     IRRRLEAAHGLIRKGGRKVSEICFEVGFKNLSHFSKIYKIAYGVPPTEDI"
     CDS             complement(18787..20436)
                     /NRPS_PKS="Domain: AMP-binding (11-443). E-value: 1e-97.
                     Score: 319.2. Matches aSDomain:
                     nrpspksdomains_ctg6_72_AMP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     380.5; E-value: 1.7e-115)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_72"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-108, bitscore:
                     355.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELHNRTLGQWLEHWAENTPDKEYIVYSDRDLRFTWSEFNKRVDD
                     MAKGMLAIGITHGTHVGVWATNVPDWLTFLYAGAKIGAVLVTINTNYKQSELEYLVENA
                     DIHTMCITDGVFDGSYVDMVYTMLPELKTSQRGYLKSERFPRLRNVVYIGQEKYRGMYN
                     TPEMLLLGQNIKDETLEAAKARVNCHDVVNMQYTSGTTGFPKGVMLTHYNIANNGFLTG
                     EHMKFTADDKLCCCVPLFHCFGVVLASMNVLTHGCTQVMVEKFDPLLVLASIHKERCTA
                     VYGVPTMFIAELNHPMFEMFDLTSLRTGIMAGSLCPVELMKTVDEKMHMRVTSVYGLTE
                     TSPGMTHSRIEDPAEVRYNTVGHEFEFTEVRVIDPETGEECPVGVQGEMCNRGYNNMKG
                     YYKNEAATNEAIDKDGFLHSGDLGVRDENGNFRITGRIKDMIIRGGENIYPRELEEFLY
                     HFPGVKDVQVAAVPSKKYGEEVGAFIILHDGVTATEEEVKDFCRGKIARHKIPKYIFFV
                     DTFPMTGSGKIQKFKLKDLGLKLLQEQGITPA"
     aSDomain        complement(19108..20403)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg6_72_AMP-binding.1"
                     /evalue="1.00E-97"
                     /label="ctg6_72_AMP-binding.1"
                     /locus_tag="ctg6_72"
                     /protein_end="443"
                     /protein_start="11"
                     /score="319.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LEHWAENTPDKEYIVYSDRDLRFTWSEFNKRVDDMAKGMLAIGIT
                     HGTHVGVWATNVPDWLTFLYAGAKIGAVLVTINTNYKQSELEYLVENADIHTMCITDGV
                     FDGSYVDMVYTMLPELKTSQRGYLKSERFPRLRNVVYIGQEKYRGMYNTPEMLLLGQNI
                     KDETLEAAKARVNCHDVVNMQYTSGTTGFPKGVMLTHYNIANNGFLTGEHMKFTADDKL
                     CCCVPLFHCFGVVLASMNVLTHGCTQVMVEKFDPLLVLASIHKERCTAVYGVPTMFIAE
                     LNHPMFEMFDLTSLRTGIMAGSLCPVELMKTVDEKMHMRVTSVYGLTETSPGMTHSRIE
                     DPAEVRYNTVGHEFEFTEVRVIDPETGEECPVGVQGEMCNRGYNNMKGYYKNEAATNEA
                     IDKDGFLHSGDLGVRDENGNFRITGRIKDMIIR"
     CDS_motif       complement(19207..19293)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_72_0002"
                     /evalue="1.40E-03"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg6_72"
                     /protein_end="410"
                     /protein_start="381"
                     /score="11.2"
                     /tool="antismash"
                     /translation="PVGVQGEMCNRGYNNMKGYYKNEAATNEA"
     CDS_motif       complement(19804..19854)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_72_0001"
                     /evalue="2.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg6_72"
                     /protein_end="211"
                     /protein_start="194"
                     /score="23.3"
                     /tool="antismash"
                     /translation="QYTSGTTGFPKGVMLTH"
     CDS             complement(20449..21030)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 92.5; E-value: 6.5e-28)"
                     /gene_kind="other"
                     /locus_tag="ctg6_73"
                     /transl_table=11
                     /translation="MGNNKIIGAKIKNIRESKQLSIEEVAERSGLGIEQIERIEGNLDF
                     PSLAPLIKIARVLGVRLGTFLDDQAELGPVVCRKKDSEADGIGFTNNATQGHKHMDYHS
                     LSQDKSGRHMEPFLIEIAPSEEGEDFILSTHEGEEFIYVLNGVVEINYGKNTYILEEGD
                     SIYYDSIVAHHVHAAADNKARILGVVYTPY"
     CDS             complement(21190..21459)
                     /locus_tag="ctg6_74"
                     /transl_table=11
                     /translation="MYLDSAKKKELFEKYGKSATNTGSAESQIALFTFRISHLTEHLKV
                     NHKDYATERSLKMLVGKRRRLLDYLIKTDIERYRAIIKELGIRK"
ORIGIN
        1 ctgttttgat ggattttctt tcagaaaatg aagctgtgtt taaaaattca gttcgattga
       61 ttgaacagga gaacaaaggt gtttctgcag cgaggaacca aggtattaaa gaagctagag
      121 gtgagattat tgcctttctt gatgctgatg acgagtggtt acctgattat ttaaaaacta
      181 tcgctttctt ggttgaaaaa tatccggaat gtgatatttt tggtacagct tattcattta
      241 agatgaataa tatgataact cccgcatcaa ttgattatta ttcttttaaa gagaatgagg
      301 gtattttaga taattatttt acgatggcct caaaagcgag aggacctatt tggacttcag
      361 ctgtggctgt tcgaaaaaag gctattttat ctattggttg tttccctgag ggcatttctt
      421 taggtgaaga tgtaatcgtt tgggctaaat tagcttgctt gtataaaata gcttattcga
      481 aatcaaacct agcattgtat agaagagata gcagttgcta tttgagtgtt aagaaaaata
      541 tgcagccagc aataaaagaa gactatgttg gtatagagct ttggaggcta aactgctctt
      601 atcagataaa agacttagat aattatgttt atctttggta caagataaga tttgtaatct
      661 ttgtttttga taatgataag aaaagtgcat ttttggagta tatacgttta ttgccttggg
      721 gattattgaa tttggattgt aactatcatt tgtttttaaa ttgtttacca tattccttgt
      781 tagttaaatt aaatacttgt gttcggagga tatttagaaa aaaagtttga tataatttta
      841 gattatggaa gaaaaccaac ataccgaatt caaagagtca tggcatgacg aatatacccg
      901 ttatatatca gctttctgta atacggaggg tggtgtatta tatatcggta tcgatgataa
      961 aggagaagtt gtagggatag agcagccaaa gaagttgatt gagaaactgc cgaactttat
     1021 cgctcagaaa acgggtatta tgcctcttat ccatttgagg gagaaggccg gtaaagaata
     1081 tttggaaata gaagtccaac cttctgccat gccgatttcc gtgcatggac ggtattatac
     1141 ccggagtgga agcgttactt ccgagctaca agggaatcag ctaaatatgt ttttggctgc
     1201 gaaaatgggt ttgacatggg aaagtgtgat cgaggaggat ttctcattgg aggacataga
     1261 taccgatacg gtagaacgtt ttaagctatt ggctaaagac cgggttcctt ccatcgagca
     1321 ggaaacggat ctgctggctt tgatggagcg gttgaatttg atcgtaggag gccgtttcaa
     1381 gagagccgct gtagtcttgt ttggaaagaa tgtgcagaga tatgtgttac aagctcgtat
     1441 taaaatagga aagttcctta ccgatacgga ggtactgaca accgatattg tcgaggggaa
     1501 cctgattcag caggttgatc gggctttgga tatattgcga acgaaatatt tattaagtta
     1561 tatatcgtat gaggggattc ataggcgtga gaaactggtt tatccctacg aggctctgcg
     1621 ggaagcctta ttgaattcga ttatccatcg agaatatttt gtttcttccg aaattcaggt
     1681 acgtgtttac gaggacaagc tggtgatagg gaatgaagct cgtttgcacg atattacggt
     1741 tgaggacttg tctcgtcctc acccctctag acctcataat aagttgatag cggatgtttt
     1801 ttacaaagct ggctttatcg agagttgggg acggggaaca caacgtatta ttgacaactg
     1861 cttggcagaa ggattatccg ctcctgtata tgagcataag atgggttttt tatacttgac
     1921 tttttttcat gagcggataa atgagcggat aaatgagcgg ataaatgagc ggataaatga
     1981 attgtcggat atggaacggg aggtatatca gatcttgcga gaggagccta ctatccgtca
     2041 aatagattta gcaaatcgtt tggatttgac agagcagtat atccggaagc ttataaaaaa
     2101 gttgaaagag catggttgga ttgaacgcat tggagctagg aaaaatggtt attggaaaat
     2161 aatagagaag tcatgaagat attgatatta aatacctctg aattaaccgg tggagcggca
     2221 gtcgccgcaa accgactagc gaaagcattg ggtaaatctg gtgtagaggt ttctatgtta
     2281 gtacgtgatc ggaaaacaga ccatgtaaaa gttttctctg taaataattc atggacttca
     2341 cataggctta attcttttcg cttcatttgg gaacgactga taatctttat ctgtaacttc
     2401 tttagcaaga agaacctctt tcaagtttcc atagccaata caggcacgga tttatcgaag
     2461 cacccattag tgcaacaggc ggatgtgatt catctgcatt gggtgaatca aggatttttg
     2521 tctctttctg atattaagaa attagtaaat accggaaaac ctattgtgtg gactatgcat
     2581 gatttgtggc cagctacggc tatttgtcat tatccgggag gatgtgagaa gtatatatcg
     2641 aattgttatc agtgcccgat gctgaaacga aatccgtttt ttgatttagc ggcttctgtt
     2701 tttaaggaga aagggaaaat agggttatct aagattacat ttgtcggttg tagccgatgg
     2761 ataatggaag aggcccaaaa aggcaattgg ttgagaacag cctgttttac ctcgattcct
     2821 aacccgattg acgtgacagc ctttaagcgt atggaaaagc gggtggcccg taaacgattc
     2881 gacctgccgg aaggtaagtt ccttcttctt tttgccgccg ctaagctttc agatacccgg
     2941 aaaggagcga tttttttgat cgaggcttgc gaaaaactaa aagagaaata ccaagatcgc
     3001 atagaaatcg tgttgatggg aaatagctcg gaagaattga ttagccagtt tccttttaag
     3061 gtgaatacgc tgggatatat atcggatcaa gactctatga tttccgttta tgcctgtgcc
     3121 gatatgttcg ttattccttc gttggaggat aacttaccca atacgattat ggagtcgatg
     3181 gcatgcggta cgccttgtgt gggatttgag acaggaggga ttccggagat gatagatcat
     3241 ttgaagaatg ggtatgtagc taaatataag gatacaaatg atttggctgt agggattaag
     3301 tggataattg acaaccaaga gacttttcga tttagtgagg cttgcgtccg caaggtgcat
     3361 gattgctata gggaatcggt tattgccgaa aaatatatag ctttgtatca gagcctgtgt
     3421 aataagagaa aatagcgtga aagaagatca gcatatcgaa gtaagaatga atgcttgctg
     3481 gtaagtgatt gaaagcaaat gaaaattgct acatttgtgg aaaaatggaa taaatggacg
     3541 atcagcataa gcctgaatgg attaaggtgg acgagtggga ttttgtagaa tatgtggata
     3601 gcttgttgcg tagtcaagag gctgtcgatt tagagtttaa gaccgctcgt gccggattcc
     3661 caaatagtgt gtgggaaacg tattcttcat ttgcgaatac agatggagga actatcgttc
     3721 tgggaataaa ggagaaaaat ggggcactat ttgtggaggg acttcttcca gagcaaattg
     3781 tgtcttatcg gcaaatcatt tgtaaccaat tgaataatcc ggattgcgtt aatgttaatt
     3841 tacttactga caagaatatt caagaggtag actatagagg aaaatctctt ttgctgattt
     3901 atgttccgag agcatctcgt tcacaacgtc ctgtatattt aacaagaaat cccttgaatg
     3961 gacatactta taaacgaaat aatgagggag attataaatg tacggatacg gaagttcgca
     4021 gaatgattgc cgatgcggat gaggaacatc cgagagattc tcgtatttta tgtaattatt
     4081 caatggaaga tattgatttg gactcactta aacaatatcg actgctactt tctagtcgtc
     4141 agccagatca cccttggttg acacttgatg atatggcttt tttgagaaaa ttgggaggat
     4201 atcgacaaga taggcaaaca ggtcaagaag ggtttacttt agcgggtata ttaatgtttg
     4261 gaaggacaga aagtataacg gataatgaat gtgctccatc ttattttccg gattatcagg
     4321 aaaaaatgtc ggtagatgag aatgttagat ggacagatcg catttgtatg gatggaactt
     4381 gggaagcgaa tctttttcaa ttttatcggc gtgtgtatcc taaattatca tctgtactgc
     4441 ctaagccatt ccgtttggag aatggtgtga gattggaaga tactaccacg catgtcgctt
     4501 tacgtgaggc atttgtaaat acattggtgc attgtgatta tatggaggaa ggaaatataa
     4561 cgatagaaca atggaaagat cgttatgtat ttaaaaatcc cggaacactg ctagtgagta
     4621 aggcccagta ttatgccgga ggtgaaagta tatgccgtaa taagagcttg caaaagatgt
     4681 ttatgctgat tggcttctct gagaaagcag gaagtggggt gaataagatt tttatgggtt
     4741 ggaaaaatgc gaattggaga cctccatttg tggaggagca aagtcacccg gatcgggtgg
     4801 tgttgaattt accgatggaa agtttgtatc cagaggaagt cttagaagaa cttaagcgtc
     4861 tgtttggacg ggaaattgaa agaattccat atgatcaatt cacggttttg gctctttgtt
     4921 actctgaaaa acaagtatct aatgaaagac ttcaatatat tttgaaccaa catagctcaa
     4981 atattacaaa gctactaaaa agtatgtgca atgctggttt tttggagtct ataggaaatg
     5041 gccggggaac taggtaccgt ttgctgtttt tggagaagga tgaaagcaag cctcaaaagg
     5101 atgaaagcaa actgaagaag gatgaaagca agtctcaaaa agatgaaagc aaactggaga
     5161 aggatgaaag taagaaatat atgcgttatg aggatttgtc gaggttaata ctatctgttt
     5221 gtgaggatta tgtagctctg gaaataatag cggaagctgt tcatagagag gcttcttatt
     5281 taattaatcg ggttatacca agaatgttag aggatgggct actagagaga ttatatccgt
     5341 cttctcctaa gcatccttta caaaaatatc gtgtgagaca agtcggaaat ttataagaga
     5401 taatggaaat gaatcagcaa cctacatttt cgatcataac gatcacctat aatgcggagc
     5461 gatggttgga gcgtacgata ttgagcgtac ttagccagtc gtatccgaat atcgagtata
     5521 tattgattga cggagcgtcg aaggataaga ccgtagagat catcaagcaa tatgagtccg
     5581 gtatcgcttc ttggataagc gagcctgata aaggcttgta tgatgctatg aataagggat
     5641 tgaagcgggc tacgggggat tatgtgtggt tcctgaatgc gggggataca ctttataccg
     5701 cagataccgt gcaaagaatt gtggcgtctt tgaaaaagaa agtatctttg ccagacgtga
     5761 tttacggaga gacccagatc gttgatgcgg agggtagatc attagggatg cgcagattga
     5821 aagcaccgga gaaactgact tggaaaagtt tccggatggg aatgttggtt tgtcaccagt
     5881 cgtttatatc aaaacgggag atcgctccgt tatataatac ggaataccgt ttgacggcgg
     5941 attatgattg gtgtatccaa tgtctgagac gatcgaaaag aatacataat acacgtttga
     6001 ccctgtctaa ttttttagag gaaggattaa gtagtgtgaa ccggaaagct tccttaaagg
     6061 agcgatatga ggtcatgtgt aagtattatg gcaaggtgtc gacgattctg ttgcatggtt
     6121 ggttcgccgt gagattctat tttgccaaat ggtttaaagg tagagtataa acaataaatt
     6181 atagataagt tttatgcgga gtataatgag taaatgggga aaacatatcg cagcgatagc
     6241 cgtattcttg gtattgacgg tgatttattt ttctccggcc gtatttgagg gtaaggtagt
     6301 ccggcaaggg gatacggaaa aggctatcgg tatggggaat agccagatgg atgaatatga
     6361 gaagacggcc caaccgggag aattcagtgc atggtctgat gctatgtttg gcggaatgcc
     6421 ttatgtgtcg ggatatggaa atccggctcc acgatttccc ggatatcttt tagtggagaa
     6481 gcctttaaaa gcgctggggt atatggatgc ggggatggtg tttaccggat tcgtttgttt
     6541 ctatatcttg atgtgtgtca tgggcgtaaa ttggtggttg gcgatcgctg gtgctatcgc
     6601 tttcgcttta gcatcttata atctgatcat tatagaggcc ggccatgtca cgaaagcgta
     6661 tgtaatcgct tatatgccat taacgttggc gggtatggcc ctgttgttca agcgtaagta
     6721 tttatggggg gcggtcgtgt tcttgttggg tgtcgcattc tctatcgcga atacgcacct
     6781 gcaaatcact tattatttat tattactttg cttcttcgtt tatttgggat atttgttcaa
     6841 taaactgaag gaaaaagctt ataaagaact gggtacggta accgctatta tggctggatg
     6901 cgtgatattg gcggtgttgc cgaatgccca gaatatgtat gctcaatggg atttgggaca
     6961 gaactctatc cgtggggcta cggaattaac gacaacgacc ccttcgggcg agaagatttc
     7021 ttccggctta gacaaggatt atgcgttcgc ttggagctat ggaaaagggg agttgttgac
     7081 cttgttggtc ccgaatgcct atggtggaag ttcaggtgga atgctaggcc cggattctga
     7141 gctatataag gaattaaggg cgaaaggcgc tcaagtcgga aaagaggtac aggctcctac
     7201 ctattgggga gagaagacat ttacttccgg gccggtttat ttcggggcat tggtctgctt
     7261 cttgtttgtt ctgggaatgt tcgtgatccg gaatccgatg aaatggtggt tattcggagg
     7321 ttctgtcttt ttgatattgc tggcattggg acgtaatttt gatagcttca atgactttat
     7381 gttccattac ttgccgatgt ataataagtt ccgtaccgta gagatggcat tggttattcc
     7441 gggtatggta tttcctatta tcgctatatg gggattgaaa gaggtgttat ccgagaccgt
     7501 gagcgatgcc ttgttgaaga aaggattgat cgctgctttg gctatcacgg ggggcatttc
     7561 tttaatcctt tggttgatgc cgagtatgct gttggatttc cgttcttctt tcgacgctca
     7621 atatcagttg ccagattggt attacaacgc cttgttaatg gatcgtgctt ccttggcttc
     7681 ggcggatgcg ttgcgctctt tggtctttat cttattaggg gcggctttgt tgttctggtt
     7741 ctatacctcg aaagatcgga aaaaggtggc gacattcgta gggatcggtg ttgcggtctt
     7801 gatgttggtt gacttatgga cggtggataa acggtatttg aacgatagta actttatccg
     7861 ccagaaacct acagaggtat ataaagagac ggtagccgat caagaaatca tgaaggataa
     7921 ggacctttct tatcgtgtct tgaatttgaa taatcctttc ttggagacaa cgacctcgta
     7981 ctatcaccat tccgttggtg gttattatgc cgcgaagctg agacggtacc aagaactgat
     8041 cgaccaccgt ctgcaaggag agcttaactc ggttatcgag gctttccaga aagcgcagat
     8101 cgcggaggat ttgatggggg cgttcgctgc ttgcccgtcc ttgaatatgc taaatacacg
     8161 ttatattatc tataatccgg agcaaccgcc tttgaggaat ccgttcgctt tcggcaacgc
     8221 ttggtttgtg gataaagtgg aggtcgtgga gaatgcggat gcggaaatag cggcgttgaa
     8281 tacgattaat ccgttaacga cggcggttgt cgataaacgt ttcgctgatg aggtgaaagg
     8341 tttcacgcct caattggact ctaccgctac gataacattg gatagttatc gccctaataa
     8401 gttagtttat acgacgaaga ctaattctga gcaattagca gtattctctg agatctatta
     8461 tcaaccggga tgggaggcta cgattgatgg gaagcccgct cctcatttcc gggcggattg
     8521 gatattaagg gctatgttag ttcctgcggg agagcatcag atcgtatttg agtttagacc
     8581 gcaaggttat attacggcgg cttatataac ctcatttagt tcattgataa tccttttgtt
     8641 attgattgga gcgatcggtt actcgatctg gagagctaaa aaagacaaga cagcctaaat
     8701 atccagttgt agagacgggg cgtgccccgt ctcggcacag actaatgggt attttaaagt
     8761 ttccattttg aggagatgag acggggcacg ccccgtctct acaactaggt ggaaattggt
     8821 aacgattatt cgttatggat aaagccaagc agttttctcg ttagggtttc ccacgagtgg
     8881 gctgcttttt ctttggatat atcaagtcgg atatgaataa gactgggttt tcatcttctt
     8941 cttttcccat gaattccgct ggaactttta gtaccaattt cttcgggttc cgggaggaga
     9001 tcagcatgaa tagatcattt aaattttttt gttcataaat aattgacaga ggtgggcagt
     9061 tcattttttc tatttcaaga atttgtttgt ctgcgtgatt aaaaaggaag gctcgaaaat
     9121 caactaaaac taaatcgaat atgccttcag atacttcttt taactgatat tgcgggtatc
     9181 cgaataatga cattccgtta gaggtaaaca gatgatttat aaaagagctg ttctgtacct
     9241 ctaattctgt ttttgatgga ctgatgtctt tccttgaaaa acgagcgaaa ggttctaaat
     9301 tattcactaa gtaaagcgtg tcttcgtaga tccctttata gatccattga ttatccactt
     9361 gaaatagact gataggtatg ggattatatg gacctgccgg ttcggagatg ggaatggggg
     9421 gtgttccaat ccattccccg gctagatttt gtttgtaggc catttgcttt tgattgcctg
     9481 cgtatgggaa gcagacaagt gtagagtcct tgataaataa taagtcacat aactgctttt
     9541 ttgcgacgat tggtatcgca gtcaattgtt tgccactcga tagatcataa cgaattattt
     9601 cttcggtatt tcccatttct acgaagacaa gttgttcact cgtaggattg actgtacagt
     9661 tgaataaaag accatgttcg tcgggacctt ctccgaaatg ggagatctcg cggataaaat
     9721 gtcctgtatg gtcgaatacg aggattcgat taaaggaata agcgacaata aaatgatctg
     9781 tagggtagat gttaaacgat ggatcaagta ggcaatcttc agtagtctca agatctatcc
     9841 ttgtccattt ggttgtataa tcatccaatg ataccgttgt tttgggaagg tcatctttgg
     9901 atagatccat tgtgaatata ccgttattat cttggggctt tccgcaagat aataataaaa
     9961 ggaatagata tgtaatgtat ttgttcatgg ttgttttagt ttattcgtta atcatgtgag
    10021 acataaattc aggataatct atacttcctt gataagagaa tgctttggga tttttttcga
    10081 ttatttctgt atacaaaaat agccttcttg cccaataact ttttatataa ctgcaatatt
    10141 gcgatctaaa atcttttgat atttgtccat tctttactgc ggttgtccag cattccccac
    10201 aaaacctaaa tgcccagcag ttggaacata gtggagctat ttctcttgag taatctgcta
    10261 tgagttgtga tatttttttt atgtcaaatc ctgttgatac atcacctatg caaaactctg
    10321 tttctgaatt tagtttctcg catggcaaaa agatcccttt agaattcaag aaaatacttc
    10381 tcatcccagg tatgcaggct ccattaggcc aaaagaactt aaattcatca aaagctatat
    10441 tacttcttaa attgatatac atcatttctc gatgaatagg tagggctctt agaactgctg
    10501 gtatttcaga agttttattg attcctttta tatggatttt tttatataac ttaaaaattt
    10561 cgttttcagt tttttttgtc caatctaaat attttacttc gcttaaatat ttattttctt
    10621 cgtaatttat ataattaaga cttaatggaa ggtctgctct tttcagcgta gggaacatat
    10681 cgtatgtaaa aaagtcaatt aaatctttga ttttgtattt cccaggtgat aatgtcgctg
    10741 agaattttat attattttca aaaaaatcat gatgtaatcg tttgatagat tctatgtttt
    10801 ttatgacggt gttaaaactc ccaacgccat taggaaaaat cctgttttta tcatgaatgt
    10861 tttgaggacc atctaggcta atggtgatct ctacattatt ttctacaaag aaagacaaaa
    10921 ttttgtcttt tagtaaagtt gcatttgtgg taattgtgaa aattgcgtta tcacatttac
    10981 ttcggacata attgatagtt tttcttatta tgtcaaaata tagaagaggt tcgcctccat
    11041 agaaacctat ttttctaata ttagagtctg tgctgtgttc taagaataaa ttaacacctt
    11101 tttctatata attccactcg atttgattgt tgctgttatg tcttcttgat ttcgtatatt
    11161 tcccagagaa tatgcagtac tcgcatctga gattacattc ttcagttata tttatgcata
    11221 ggaaggttaa ttcttttttg agtttctttt ctactttttt agcgttagaa tagatggatg
    11281 aaatggtgaa tttaggtatt ctattaggtt ttattagttt tttgtcgttt tggcaataat
    11341 ctaatgtctt aaatagatct ataatctcct cttttgaaaa aatattatga tatttttgag
    11401 tgaattcatc tgtgtcaagg ctaattagat cgtctaaata ctcaaaaaat attcttggaa
    11461 ctgtaaaaat ggaattggaa tatctatcgt ataggtaata ttttgaattt aaaatgaaac
    11521 ctagtactgg gctatttttg tattctagtt tttccataaa gtgaaagctt atgcggggag
    11581 agaaatctcc ccgcaggtta ttaatgtgaa attgaagctt tggttgagcc tcctaaaccg
    11641 ctattcccat tacctgggct acagatgcag caagcacatc cacctccggt gagtaacttt
    11701 tgctgtccgg cagagattac tttaatctcg tctttaaagt tttcccatga gattttcttc
    11761 gttttttgtt tcatacgctg aataatttta tatgttagta atatatatca aacgcactcc
    11821 cgtttgattt taatatctta atatatgatt tgatgacttg ggcgtaatca tattttatta
    11881 ttttacaata tttatttatt ccttttcgtt ctttagaagc atataatgta taaaaacaaa
    11941 aatcgcagaa tctataaacc caacattttt tacatgtttt atttctgaag ttagtgtatt
    12001 gtgtcattat atcttgtagc ttgtttaatt ctatagattt atcaatattt ccgatattaa
    12061 atccttttat gtaatataaa tcgctgcaca tgaaaatgtc acctgtcggt gatatatata
    12121 tcttgtttaa gtaaggaagg cagcttttta tgggaataaa tcttgtttct tcttgcagga
    12181 tgttgtttga tcttcttgaa aagaacatca tctttttatg taagtcgctg gaaattataa
    12241 ataaaggggg ggagctattt tcgaatcctt gtatgtgtat attttcatat attgataaaa
    12301 aggattttgt gaaattatta tggaatttcg tgtattcatc gtttatctca gatgattgaa
    12361 tatttatagc aaatttattt ttgaaatgtg cttctagata gttggtgaat tcggaaaggg
    12421 aacttgttat attgattgaa tatacggaat ttattgttac atattgttcg aagtatcttg
    12481 tgttgtttag ttgtattttg cgtatattgt tatatactat atcaaaactg ttttttttat
    12541 cttttgataa tctgttcaat ccttgaattt ctttttctcc atcaaaactt atagttatat
    12601 gaaacatgtt ttcaattaga taatttaata tgtcttcttt taataaagag ccatttgtta
    12661 tgattgtgaa tgatactttg ttgttgaatg tttttatgta ttcaacaatt ttttttatta
    12721 agttgaactt gagtagaggc tctcctccta tgaatgatat ttggtggttg caattattgc
    12781 tgtttttgaa ataaaaatca actgcttttt ttgctgtttt taaggacatt gatttggagt
    12841 atgattcttc tatttttttt gttaaagaaa caatacttgc atctgaagtt gcacgtttct
    12901 gtaatattta gtgttaattc agataacgta ttatctatgt tttgttttaa tgtgttgagc
    12961 ttaggaatcc attgattaaa gtagtttgct gaaagttttt tattaataaa aatattttca
    13021 atggaacttt caaaaagtga tagataatct agattttcat agatatattt actgacttct
    13081 aaaatgttat tagaagacct gtcgtatatg taatataggt tgtctatatt aatacctaat
    13141 gcaacattcc ttttgtatgt tttaaataga tcttccatat gaatagattt taatagctaa
    13201 atgcggaaat ctcagttatt cttgtttgct ctataatgaa ttcatccggt acagtacttt
    13261 tgttatattg tttgaagaaa tctttaaaga atattaggtg atataataaa acctcatact
    13321 tgtttttata taatagggtt cctttcttcc atgtcatatt tccaggtagt ccttcaagga
    13381 tatgaaggtt gaagtatggc tttaataagc ctttatcttt catttttaat acaacatgag
    13441 tcatgctttc tatctctgta tttatattat atgcatcttt tgattttgca aattcatcaa
    13501 aagcaaagtt tgtttcgtca aagcaaaagt ttttttcaga tagaaaaact tttagataat
    13561 ttttgctttg cataaatagt gtgtttgttt tatgttcgtt cttgaacaat gtaaaacacc
    13621 cggataaata atcttgacgg acagttataa tttcatattt agaaagtata ttttctgtta
    13681 taaatgctct tatattccca aaaatgacat caatatcaca gtatccccaa aaatcatagc
    13741 cttctatata tctagaaaat atgtaaccat atgccggttt aaaatcacat agtttgtatc
    13801 cattttgaat tggagtattg atgtttaaag atctatgaac atctttttta aagtcttgta
    13861 gatcatatct tttgatttta atattgttag agatcccttt actagtcatg tcttgatcgc
    13921 aaaggatgag aaagtcaatg tccttgttga aggaacaaga ttttaggaag aatttaaaat
    13981 accaaggtaa ttctcctatg tagatgcata ttatcaatat ttgttttctc attcttgtat
    14041 ttaacgtgat ttcgcaatgt aatgatttta gagaaataag tatgtatgtc ttttattttt
    14101 tttgcgttaa aaaaataaaa tgcatctatc tgtgctgttt gaagagaatg tcaagtggaa
    14161 aatagtcagt aagtcctaga tgaaaccgct attgataaaa tcgagcagtt ttctcgttag
    14221 ggtttcccac gagagggctg ctttttcttt ggatatgttc gcagggatgg tggcttgctg
    14281 tgagggggtg aaaagttcct cgataccttg ggcgagggcc gttgcggata tctcaggcac
    14341 tacgatgcct gtacccggct tttcgatgct gttcttgaaa tcgcctacgg gagtacttaa
    14401 cataggtaaa tcgtaattgt aggctacgga tacgacaccg ctttgagtgg cggagcgata
    14461 ggggagtacc aaggcatccg ccgctgagaa ataaatgggg atttcctcgt cgctgatata
    14521 ttcacagtgg acgaatatac gttcttttgc cggagatgca tcgatcagag cctgatactt
    14581 ctcgaaacta ccgtaacatt cgccggctat aatgagatgg taatcctcgt taagctgtcc
    14641 catcgcttct atcagcagat ctaatccttt ataatcccgt atcagtccaa agaatagaag
    14701 attctttttg gacggatgga ttcctaattt ccggcacgcc tcgttcttgt tgatcttact
    14761 cccgaaatga ttgtaaagcg ggtgtgggtt ctggatatat ttagcgcccg ggtaaagttt
    14821 ccgcaaatca taccgcacgt tatcgctcat cacgataaag ccatggcatt gcttgaaaag
    14881 taacgaagct aaaggcttgt cgaagaaacg cggctcatgg ggaatcgcat tgtggataag
    14941 ggtgattacc ttgcaatgct tcttcatccg gttcgctacg tgggcgtatc cgggaacgaa
    15001 aaaggacatc cagtaagaga taatcagtac gtccggcgca taggaacgaa tggcgtttac
    15061 ggtactgaaa taactaaccg ggttgacgct atctaatact cgcacgctct cgatttcgat
    15121 cgcacggtct cccgcttcta cgtattgagt cttgccggga aataagatat ccggataaag
    15181 acgtttgaag ttgaaagcct ttacttcatg accttctttt actaattccg tatagagcat
    15241 cccgctgaat tgggcgatac cgccacgata gggataaata ggggagagaa tagcgaaacg
    15301 catggtaatt gaaaattaag aattgaaaat tgaaaattaa gaatcgagaa ctacaggagc
    15361 tgccctccct tcattatcaa ttctcaactt tcaatcttca attaattagt atctgtaatg
    15421 atcagccttg tacggtcctt ctaccggtac accgatataa tcagcttgct tttgtgataa
    15481 tgtagataat ttcacgccga tacgttccaa gtgtaggcgg gcaacttcct catccaagcg
    15541 tttcggtaag cggtatacac ctacctcata agccatttgc cataagtcca tctgggcaag
    15601 cacttggttc gtgaacgagt tactcattac gaatgacggg tgtcccgtag cgcaacctaa
    15661 gtttaccaag cgtccctctg ccaataagaa gatggagttt ccgttcggga acgtatattt
    15721 gtccacttga ggtttgatat tcgtgtgctt gatattcgga tagttgacaa gcttgtccac
    15781 ttggatctcg ttgtcgaagt gaccgatgtt acatacgatc gcttgatctt tcatctgtgt
    15841 catatgctcg atcgtgatga tatcgcagtt tccggtggtt gtaacgaaga tgttaccctc
    15901 tttcacggcc tcttccatgg tcgtaacctc gaaaccttcc atagcggctt gcagggcgca
    15961 gatcggatcg atctcggtca cgagtacgcg agccccgtaa gagcgcatgg agtgagagca
    16021 gcctttacct acgtcaccgt atccggccac gactactacc ttgccggcga tcatcacgtc
    16081 tgtagcccgt ttgatgccgt ccgccaaaga ctcacggcaa ccgtataagt tatcgaactt
    16141 ggatttcgtc acggagtcat taacattgat agccggaacc agcaactcac ctttctccat
    16201 catctgatac agacggtgaa cgccggtggt cgtctcttcc gacacacctt tcatctcggc
    16261 taccgtacgg tgccaacggc cgttatcttc ttgaaggatg cgatttaatg tatccaggat
    16321 tacctgttcc tcatgattcc cgcctttgcg gttgatggtc tccgcgtcgt tctccgcacg
    16381 atagcccatg tgaatcagca aggaagcgtc gccgccatcg tcaacaatca tgtgagggcc
    16441 tttaccttcc ggaaaacgaa gcgccatgtc cgtacaccac caatattctt ccagcgtctc
    16501 gcctttccaa gcgaataccg gtacgccgtc cgccgcgata gcggctgccg catggtcctg
    16561 tgtggagaag atgttacagc tagcccagcg aacgtccgct cccaacgcaa ctaatgtttc
    16621 gattaacacc gccgtctgaa tagtcatatg cagtgagccg gtgatacgtg cgcctttcaa
    16681 gggtttctga tcggcgtatt tctggcgtag cgccattaat cccggcattt cgtgttcggc
    16741 gatctcgatc tctttgcgac cgaattcagc caaactcata tctgccactt tataaggcag
    16801 attagttgga aataattgtg acataaatta atactataaa tggttgagac gcgaaggtac
    16861 gaaaaagcgt tgatagtagg tgttctttat ctatgaattt ccatctaggg cagaggcttg
    16921 ccgaggggta ggtgggttcg ttactgcaac ctgccttgca gtagttctgc aacagccatg
    16981 cagtattggg ctctctgtag ttttgcgctt taatgaatac tgaaggctcc atctaccaat
    17041 agcgcgtggc catcgacgaa gctcgcttgc gggctgcata gccaaagtac ggcgttggcg
    17101 atctcttccg gtttaccgag ccgccctgcg ggaatgtcgc gcaccagctc cttctccaag
    17161 gaagggtcac gccgcattaa gtcttccgcc atcggcgtac ggataacgcc cggacatacg
    17221 gcattgatgc ggatgttctt tgccgcatag tcgatagcgg cggtacgtgt cagtccgata
    17281 acggcatgct tacaggctat gtaggccgct tgccccggaa atcccgtgac tccgccttgc
    17341 gatgaggtgt tgacgatggc tccgccgcct tgtttcagca tttgcaggat ctcataacgc
    17401 atgcagttcc agacaccttt caaatccaca gccacggtac ggtcgaattc atcgtcggtg
    17461 atttctgcca ttgggcgttg cggtgtttgt atgcctgcgt tgttaagagc cgcgtccagt
    17521 cttccgtagg tagctacgat ccagtcgatc atctccttta cggcttgcgt gtttgatacg
    17581 tcgcaccgat acgctacggc cttatgtccc tcggctacta atttctctac ctgttctctc
    17641 ggctcacgga tgtctgccaa tacggttatg tatccagcct tggcgaaggc ttcggcgcaa
    17701 gcgagtccga tacccatcgc agaaccggtt actaaagcta ctttctcttc cgttgtcttt
    17761 gtcatgatca tttgatttac attttgttat tatttatgtc gcgaagataa ggagggagtg
    17821 gtatagaggc tttgttatgt ggttcaaata gctttgttgt gtgggccatt aatattatat
    17881 atcctcggtt ggcggtacgc catacgctat cttatagatt ttcgagaaat gggaaaggtt
    17941 cttgaagcct acttcgaaac aaatctccga gaccttacgc ccccctttac gtatcagccc
    18001 gtgtgcggct tcaaggcggc gtcggatgag ccattcccgg ggcgagagag cgctacattt
    18061 cttgaaatca cgtttaaatg tggagagact gcgtcccgta tagttggcga tttcttccat
    18121 ggaaatatcg ttcatgtaat tccgctccat gaattccagt atgtctatct tccatggatc
    18181 ggtaaaatcg aagatagagg catatagatt cttgtcggta ttgagcaaca cataaacgcc
    18241 ctcgaccatt tttagttgca gcaattcgtc tgtcggttgg atcttggaat tgaaataagg
    18301 ggtcatcgac tcaaacaagc ttacgatatc gggacggttg gacggtagct tgtaaaggct
    18361 tacctgatct cgcttggcat ctttagggag agtatttcga tctaatttgc tgtaaaagtc
    18421 gcgtaggaac ttcatggtga acatcaagaa gatcgccttg aactgctcgc cattccatgc
    18481 ttgtttcgtc atctgcacac tgaagtcctt gcggatgaaa gcgcattctc ctttatgtaa
    18541 ccgggtgatt tggcctttct cgtcgattac catctctccg gaatatacat acaccaacac
    18601 atgcgaatga ttccggtgca ggcagctctt cccgccatcg aaatacatcg ctaaaaataa
    18661 atccgagtaa cgcagcgtgt tgattccgtc catagttctt taggaaaatg ggcaacacga
    18721 gaagatcgta ccgcccatta tgaagatttt aaagtaactg tcaactgtta gctgtccact
    18781 aaatcgtcag gccggcgtga taccttgctc ttgcaatagt ttcagcccga ggtctttcaa
    18841 cttgaacttc tgtatctttc cgcttccggt catcgggaag gtatcgacga agaagatgta
    18901 tttcgggatc ttatgccggg cgatctttcc gcggcagaaa tctttcacct cttcctccgt
    18961 agccgtcaca ccatcgtgaa ggatgataaa ggcacccact tcctctccat atttcttgga
    19021 aggaacagcg gctacttgca cgtctttcac gccggggaaa tgataaagga attcctccag
    19081 ctcacgtgga tagatattct cgcctccacg gataatcata tccttgatac ggccggtgat
    19141 acggaagttt ccattctcat cacgaacgcc caagtcgccg gaatgcagga aaccatcctt
    19201 gtcgatcgcc tcattggtgg cggcttcgtt tttatagtaa cctttcatgt tattataacc
    19261 gcggttacac atctcgccct gtacgccgac ggggcattcc tcgccagtct ccggatcgat
    19321 aacccgtacc tcggtaaatt cgaactcatg gcctacagta ttataacgca cctcggccgg
    19381 atcttcgata cgggagtggg tcatacccgg tgaggtctct gtcaatccat acacgctggt
    19441 tacacgcata tgcatcttct cgtccacggt tttcatgagt tcaaccgggc aaagagaacc
    19501 tgccataata ccggtacgta acgacgtgag gtcgaacatc tcgaacatcg ggtggttcag
    19561 ctcggcaatg aacatggtag gcacgccgta cacggccgtg caacgctctt tatgtataga
    19621 agctaatacc aatagcggat cgaatttctc gaccatcact tgcgtacatc catgcgtcaa
    19681 tacgttcatg gaagctaata ccacgccaaa gcaatgaaag agaggtacgc agcaacaaag
    19741 cttatcgtcg gcggtgaatt tcatatgctc acccgtcaag aaaccgttgt tggcgatgtt
    19801 gtagtgagtc aacatgaccc ctttcgggaa gccggtcgta ccggaagtat attgcatatt
    19861 gacaacgtcg tggcaattta ctctcgcttt ggcagcctct aaggtctcat ccttgatatt
    19921 ttgtccgagg agcaacatct cgggcgtatt gtacataccc ctgtatttct cctgtccgat
    19981 atatactaca tttctcaagc gtgggaaacg ctcgcttttc aaataccccc gttgagaggt
    20041 cttcaattcc ggcaacatgg tatagaccat gtccacgtaa cttccatcaa acacgccgtc
    20101 tgtgatacac atcgtatgga tatcggcgtt ctctactagg tattccagct cgctttgttt
    20161 atagttcgta ttgatcgtga ccaatacggc accgatcttc gcgcctgcat ataggaatgt
    20221 caaccaatcc ggtacgttcg tcgcccatac gccgacatgt gtgccatggg tgataccgat
    20281 cgccaacata cctttcgcca tgtcgtccac acgcttgttg aattcgctcc aagtgaaacg
    20341 taagtcacgg tctgaataaa cgatatactc cttatccggt gtattctcgg cccaatgttc
    20401 cagccattgg ccaagggttc tgttatgtaa ttccataaaa cgccggattt aataaggtgt
    20461 atagacaact cctaggattc gggccttgtt gtcggctgcc gcatgtacat gatgcgccac
    20521 gatagaatca taatagatgc tatcgccttc ctctaggata taggtgttct ttccgtaatt
    20581 gatctctacg acgccattca atacgtagat aaactcctct ccctcatgcg tggacaggat
    20641 gaaatcctcg ccttcctcgg agggagcgat ctcgatcaag aagggttcca tatggcggcc
    20701 ggacttatct tgtgagagcg agtggtaatc catatgcttg tgtccttgtg tcgcgttgtt
    20761 cgtgaacccg ataccatcgg cctcgctgtc ctttttgcgg catacgactg ggcctagctc
    20821 cgcttgatca tccaagaatg tacccaaacg tacccctaat acccgtgcta ttttgataag
    20881 aggggccaaa gatggaaaat ccaagttacc ctcgatacgt tctatctgtt cgatacctaa
    20941 cccggagcgt tcggctacct cctcgataga gagttgtttc gattcccgga tatttttaat
    21001 tttcgcgcct ataattttgt tgtttcccat gtgtatgatt tgttatttat agtcctgtaa
    21061 tgtttgataa tttgatacta aacggcgcaa atttacatta atattttatt atatctagga
    21121 ttaagacaaa taaaaagggc aatacccatt tgggattgcc ctttttaata ttttcgagta
    21181 agctttttct tactttctga taccaagttc tttgatgata gcgcggtatc tctcgatgtc
    21241 agtcttgatc agatagtcca ataaacgacg acgtttacct accaacatct tcaatgatct
    21301 ttccgtagcg taatctttgt gattcacttt caagtgctct gtcaagtgag agatacggaa
    21361 tgtgaacaat gcgatttggc tctcagcaga acctgtgtta gttgctgatt tgccatactt
    21421 ttcaaataat tcttttttct tcgctgaatc taaatacatg attcttttta ctttaataaa
    21481 ttaatactat gttatctaag cggtcgcaaa ggtagacatt cctttttgat ttgcaataga
    21541 ttctactatc ttttttg
//
