LOCUS       gnlProkkaPHLLEACA_22   23718 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PHLLEACA_22.
ACCESSION   gnlProkkaPHLLEACA_22
VERSION     gnlProkkaPHLLEACA_22
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 14:13:43
            Original ID  :: gnl|Prokka|PHLLEACA_22
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 310103
            Orig. end    :: 333821
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23718
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:21227]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21227
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..23718
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23718
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             135..758
                     /locus_tag="ctg22_283"
                     /transl_table=11
                     /translation="MLINKIKKGISLFTVFCLLTMALPFLSCSASAKGEQQSEKTNMKT
                     LTVYFSFTAGNTKRIAERVHSAVGDDIVRLEPMKPYPKNYAQAVSQGDDEVKRGYKPEL
                     KPLGVDLNKYDRIIIGTPTWWYHMAPVVLSFLSSNDFTGKTVIPFMTNAGWPGSAIKDM
                     TALAKKQGAKVENGHEFRFSSNEKHYDRMETSEKELDEWIDSLK"
     CDS             769..1704
                     /gene_functions="transport (smcogs) SMCOG1166:transporter,
                     EamA family (Score: 152.3; E-value: 3.2e-46)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_284"
                     /transl_table=11
                     /translation="MDTNKLKGHVAILSANVIYGLNIPVTKALLDKWMTPWGYMATRTL
                     TALLIFWVIQCFTPKERITRRDLLTIAIGGIMGFVVSQFLTALSLQYTSPVYFSLVIAL
                     SPLCVMMLAALLLKEPVTRQKSVGVVLGIAGAVLLIAFADSSNADGSNNLLGIGLACVS
                     IFAYSIYLIIIRSVAQKYSAVTQMKWMFLFTAIILVPLGVYEYPQQAIFSSECDWSGIL
                     ELGFVIIFSTSLGYFLMPFGMKYLRATTVSVYMNLQPVVASVVAIFVGQDKFSWDMPLA
                     ALLVLTGAYVVSSSPAREEQSKNQERTNNQ"
     CDS             1726..2559
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     93.6; E-value: 2.3e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_285"
                     /transl_table=11
                     /translation="MRNVMILTGAGQIGMAIVRRMGFGMKIIVGDKSMNHAESICDTMD
                     KAGFDTLPFEMNLASRESILSLIDEARKHGEISMLVNAAGVSPSQASIETILKVDLYGT
                     AVLLEEVGKVMQAGGTGVTISSQSGYRMPALTPEEDSLLATTPTKELLSLDLLQPQNIR
                     DTLHAYQLAKRCNVKRVMAEAVRWGERGARINSISPGIIVTPLALDEFNGPRGDFYKNM
                     FAKCPAGRPGTADEVANVAELLMGNQGTFITGADFLVDGGATASYFYGPLKPKNK"
     CDS             2564..3199
                     /locus_tag="ctg22_286"
                     /transl_table=11
                     /translation="MKQLSTVFALLLTLFSTVSCAQGKTGKATKTLETSSMETGKKILV
                     AFFSHTGENYAVGNITKGNTHIIAEMIAESTDGKLFEIVSVKEYPKTYNACVEVAKKEK
                     EAGARPAVKDDIAVEDYDVVFIGYPNWWGDMPMAVYTFIERHRWAGKTIIPFCTHEGSG
                     LSNTEKYIANACKGAKVEKGLAVRGATAQNKQEQARKAVVQWLERLGL"
     CDS             3395..3805
                     /locus_tag="ctg22_287"
                     /transl_table=11
                     /translation="MQGKPVETETIAKDLAKISTVSNSDVQAVLGDITGVMHTRMAQGK
                     SVHIKGLGYFRYTLDTVGVKDLADFDFDKQVKTVRVQFTPERERLSNKTYTRALVDSDD
                     LEWIELSADAKDDDPAQGGGNTGGSGGGEDEG"
     CDS             3916..4809
                     /locus_tag="ctg22_288"
                     /transl_table=11
                     /translation="MKLHTTSTGFLRTLISAGYLLMCLLAVGIMYLWFHEWQELEKLET
                     GNRQINAFRQEVHHVYGEMTGLSLLGESVLEWENKDLELYHVRRMEVDSLLCRFRTVYP
                     AKRIDSVRHLLEDKETLFRGIVNVLDEQVSLNRKIAERVPVIAARSAQEQPQKPKRKGF
                     LDLFGKKEKPKPTTTTTMLQALNRKEITQQQAQSRRLSEHADSLAMRNNELNRQLQSLI
                     GQMDRKVQEDLQKREVEITAMRERSFLQIGGLTGFLFLLWVVSYIIIHRDIRRIRRYKS
                     KTVSLIRQLHESDMRN"
     CDS             4878..6167
                     /locus_tag="ctg22_289"
                     /transl_table=11
                     /translation="MIAMLNTLLDFFRLDSGKEIVNTVPFRLQGVADALSAEFIPLAEA
                     KDLRLTVECNTDAILMGDKERIMQVCGNLLSNAIKFTQAGSVSLRMDYNGCVLSVVVED
                     TGSGMNVEEQQRIFSAFERLSNAATQDGFGLGLSIVKRIVDMLGGTIRLESKKGRGSRF
                     TIELPMQTADIAVTEKKKEQEQYQEPYIERAYSVIMLDDNDILLSMARDMYAHYDIHCE
                     VCTNIGDLMEAIRTGNYDLLITDLKMPETNGYEVLEVLRSPDIGNSKTISVVVATASGS
                     CTEGELLAHGFSACLFKSFGLSELMAVSEKCLSSLQSPKDEYPDLTSLLMYGDKAAMLD
                     KLITETGKDMQVMKEAGEKHDRESLDVQVHRLRSSWAVIRADKPLWKLHRLLHSDTECT
                     DNEIRRAVDAVLAMGGKIMEQVKRQKEDER"
     CDS             6164..6433
                     /locus_tag="ctg22_290"
                     /transl_table=11
                     /translation="MKVIVIEDNPVYSDYVCNLLKKGGFDTVQAYRLSTAKKLLLKAGE
                     EDIVLSDLRLPDGEGIDLLRWMRIEEKRQPFIVMTDYARGTYYG"
     CDS             6438..7424
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 314.8; E-value:
                     1.7e-95)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg22_291"
                     /transl_table=11
                     /translation="MKLGSADYIPKPLVADRLVPLIRSMHNAQEQRKSSQIPIFVRQGA
                     AYQEIKRRVRLVAPTRMSVLILGENGTGKEHIAQHIHTQGKRADKPFVAVDYGSLSQTL
                     AQSAFFGHVKGALTGADANKIGYFQEAEGGTLFLDKVGNLPLETQQMLLRAIQERCCRS
                     IGAKEDKTADVRIVAATNEDLLYRLKEYTITVPPLRDCQEDILPLAEFFLEISNRELEC
                     DIKGFDASARKALQTDPWPGNVHELKKRVQVAVLHAECDMITENDFELCTEDQPVSTVF
                     ALKDTEQEKERIRRALEQANGNRSIAARLLGIGCSTLYRKMQDYGML"
     CDS             complement(8214..10775)
                     /locus_tag="ctg22_292"
                     /transl_table=11
                     /translation="MRKKTILWLVCLIVVCTARAQHTQISGVVTDSITGEALPYASVIL
                     KGTTVGGATDGEGRFLFSVPNTPGMLQISYLGYESRECRITPKGKNLVLDICLAPTGIA
                     LGEVTVKPRREKYRKKENPAVEFVRHLIESRKESNPRNHDYFSYDQYEKMIFAKNEYVH
                     KSKKEGKAGKFDFLEEFVDTLDNGITILPVSEKEKVQTVYYRRQPRSEKQVVRGFKSSG
                     IDEIFSSDGVQQFLGEVFREVDIFKNDIPLFLQRFVSPLSSIGPNYYKYYLMDTLQVNG
                     KQCVDLGFVPFNSETFGFTGHLYVTLDSTYFVQRAVLNVPKDINLNFVSRLTIKQEFER
                     TADSTRIITKDDISVSFKLTERTKGMYARRLNIYTNHSFEPPAEEQMHVFKESAPVITL
                     QGSHRQTDDFWEEHRPEEAAKRNSNSMEKMMARLNAVPTYRITMKTLSILFNGYVPTHR
                     EQDKSKFEFGPMNSTVNNNTLEGMRFRVGGTTTTAFSKHLFLDGYLAYGVDDEKLKYDA
                     LVEYSFNERKEFRKEFPMHSLRLEYMYDINKLGQEYMYTSKDNMMLMIRRKKDRFISYQ
                     RQAELTYTQEHYNGISYNAVVRNRREYATPYAAFERIGADGTSILVDHYDITALELRFR
                     YAHNEKFYQTRNLRIPITFDALIFNASHVMAKKDFLGSDYNYHRTDIGMQKRFWFSAFG
                     YIDIIAKAGKVWTKVPWPLLILPNANLTYTIQPESYTNMNALEFINDEYASWDITYYMN
                     GNLLNRLPLVKKLKWREVFCFRGLWGHLTDKNNPAASGGEELYRFPGCTYMMGNTPYME
                     VSVGIENILKFLRIDYVWRLSYRNHPDIQKNGVRMTMVLSF"
     CDS             complement(10817..11806)
                     /locus_tag="ctg22_293"
                     /transl_table=11
                     /translation="MIMTKENIKSTYKSNDTEEWIDRVWTRPIGYWWARLFERLRIHPN
                     TVTVLSMIIGASSALFFAHGSYRTEGMNGLWLNIVAVLLLAWANFYDSADGQLARMTGK
                     KTRLGRILDGAASEVWFIPIYLSLVYRFYVHHGWEFRCLGIADTAQNTWIATLLLLGMV
                     LYSGFHCHSRQCGLADYYRQIHLFFLNGEAGSELDNSAQQQRLYDETPWKDNRLWKAFL
                     KTYVNYTRTQESQTPEFQRLMQRLCERYGATENIPQPFRDRFRRLSLPLMKWANVLTFN
                     TRAIALYVVCLADVPWLYFFFEIFVMGGLCRYMRQRHERMCRQLRKEL"
     CDS             complement(11803..12849)
                     /locus_tag="ctg22_294"
                     /transl_table=11
                     /translation="MRKRINNLFFAVGITAVVVMFCTFDVSFAEQWAYIRRANCWLAAI
                     LGLWMLLYVLNTWAWQIIIRGSGSCTISFWRLLKLTVTGFALNYATPMGMVGGETYRIM
                     ELSRYMDTRRATSSVVLFVMMHVFCHFWFWVTSIAVYLVLAFSGDLPLNTATGVVLALA
                     MLFCGGGICLFVRGYKYGMAVKLMRIIGRVPGLRRWEKRFSESHREDLEKIDRQISELH
                     GQNKRSFFGSFILEYAGRLLQSFEIFFMLRLLGIGGGGGTDGYLLTFLHSFLILAFTSL
                     FANLLGFLPLQLGGREGGFAMSVAQMGMTGGTAMFISIICRVRELFWCSVGLLLMKTGN
                     RNETTNKT"
     CDS             complement(12846..13286)
                     /locus_tag="ctg22_295"
                     /transl_table=11
                     /translation="MKTLEDICRIPVRFSEIDSMRRVWHGSFVTYMEDGRESFGRHWPG
                     IGYADMQMAGVYAPIYDLHIRYLAPLAMNDVAVIHTLYVYHRGARLDYAYRIYRESDDV
                     LCAEGSSTQLFIGTDGELLTDKPAYYREWQERYLEIGSKTEI"
     CDS             complement(13298..13936)
                     /locus_tag="ctg22_296"
                     /transl_table=11
                     /translation="MKRLFTLFITALFVCTGISAQRADIRKTAERYTKTNTLITNVKQT
                     KHNAALTKDMVTDGHFYYKKPNNQSMVFKESGEMLIAVSNTFVMVKDGKQHVAKTKGKG
                     NNPFEILQDVFRNLLSADDDVQLTDMADVKLETQGNTSIITITPTATDAKAKRRSMFTS
                     CIVTIDLKAAELRSLRINEQGENYTQYDFSNYVFDAEVSDSVFDTRTVM"
     CDS             complement(14056..14787)
                     /NRPS_PKS="Domain: PKS_KR (4-163). E-value: 8.7e-18. Score:
                     56.7. Matches aSDomain: nrpspksdomains_ctg22_297_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     217.5; E-value: 3.3e-66)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_297"
                     /sec_met_domain="adh_short (E-value: 7.5e-36, bitscore:
                     118.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKYALVTGGSRGIGRAVCIKLARMGYDILINYVSNAAEAQKTLE
                     LVRQAGQDGEILMFDVSKREQVRKAIELWENDHPEEYIEVLVNNAGIRRDNVLVFMPEE
                     DWHRVLGITLDGFYNVTQAVLQPMLVHKQGRIINVTSVSGLKGQSGQANYSAAKGGLIA
                     ATKALALEVARKRVTVNAVAPGFIETDMTEGLDTAALKNTIPALRFGTPEEVAELVGFL
                     ASPQAAYITGEVISINGGLYT"
     aSDomain        complement(14299..14775)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_297_PKS_KR.1"
                     /evalue="8.70E-18"
                     /label="ctg22_297_PKS_KR.1"
                     /locus_tag="ctg22_297"
                     /protein_end="163"
                     /protein_start="4"
                     /score="56.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGSRGIGRAVCIKLARMGYDILINYVSNAAEAQKTLELVRQ
                     AGQDGEILMFDVSKREQVRKAIELWENDHPEEYIEVLVNNAGIRRDNVLVFMPEEDWHR
                     VLGITLDGFYNVTQAVLQPMLVHKQGRIINVTSVSGLKGQSGQANYSAAKGGLIA"
     CDS_motif       complement(14710..14772)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_297_0001"
                     /evalue="9.30E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg22_297"
                     /protein_end="26"
                     /protein_start="5"
                     /score="18.3"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVCIKLARMG"
     CDS             complement(14796..16295)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 138.7; E-value: 5e-42)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_298"
                     /transl_table=11
                     /translation="MKYDVIIIGSGLGGLECGLILARHGQRVLVLEQGAVPGGCLQNYR
                     RRELTFDTGFHYVGGLDEGQSLHAAFKYLGLLDLPWHRLDADGFDRVSIGGRTFAFVEG
                     YDDFARQLAEEFPSGRIALRRYAKLLKRSSAGQFAALNPHADGFPAFSSELMATSAWHY
                     LKENIRNPLLINVLSGTSLKMELRKESLPLFTFLHGNGSFIESSWRLKGDGSQIIKSLA
                     EGIYAQGGEIICNAKVQELVEKDGKLTCAVCANGERYEGGLFISDIHPAQTCGLLRRSN
                     LIKSAYRNRINNLENTFGMFTVSLRIRPRGLRYFNYNHYIYREPNMWDFYQDNTCVGGV
                     LVSCRVPEDGSEYTGQVDLLTPMLWEQCKSWNYTQTGKRDSDYKAMKKRMADECIELAE
                     CFLPGLREQSRCYTSTPITWRDYTLTPEGSAYGIRKDFRDPLLTMLSPRTPVPNLLLTG
                     QNLMLHGVHGVTMTAFHTCAEVLGKETIWGIIGNEINGKLK"
     CDS             complement(16292..18784)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     52; E-value: 5.6e-16)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_299"
                     /transl_table=11
                     /translation="MTELCIRIYRYFRRHYALYWFSLAGLFLFCGYFAAQIHLEEDLNK
                     LMPSSRNEDSSTKLAFANLRIKDKTFLLFEGVDGASTERIIEVCDAFIDSLQVRDAAQG
                     EGHGSVGDVFYRLSDDLLPDAIDYLSGHLPAYIDTSLYARIDTMLTQEHFTRQMERNRI
                     DLTGDFGSMYPELIQADPIGLRNLLAEQMKPLAKGGTGGYHTIDGHFFVPDSTVCVAFL
                     TPRYSATNTGQGSSLFRLLNGLTDEFSETAPDVRICYHGTPASGFYNASQIKHDLTGTI
                     GGSLLLVLLFLCVCFRNRDTLPLLLLPVLFGTLFGLAMMYFLKGEFSLLALGIGAVVLG
                     VAMSYVLHVLTHYKYVGNPEQVLREQVKPVCLGCLTTIGSFMGLFFIDTALLQDFGLFA
                     AFAITGTTAFSLTYLPGLLRPEKNRMNHRAFTAIDRINAYPFHRKKGLLAGIAVVTFVC
                     IGCYVACGTQFDADMHNLGYKAERTTYSENLLLRKTYTADKQKYFAASGQTMEEAIERF
                     ALLSHKLDSMQRIGLVKNYTHTDKLFIPLRVQQERMEAWKRYWTDERLEQVRRLIAATA
                     PEAGLRPEAFEPFFDYATADYEPDALYKAGIIPPGYWSTLMEQSYNDEHLCFTSVRCAN
                     DTVRSHMSDYYRICDAIVTEPNLMVLDTYYYTTDTLTAMNEDFNVLQWVSMLFVFVVLL
                     VSFRFNLKHTLLAFLPILLSWLIVLGAMTIFGMRFNLINIIISTFIFGIGVDYSIFVMN
                     GLIGGEKDSRLLAYHKTAIFFSAVTLIVTVGSMLFAEHPAIRSVGFSTLVGLVSAVGLS
                     YVVQPAVYGWINKKGGKA"
     CDS             complement(18781..19191)
                     /locus_tag="ctg22_300"
                     /transl_table=11
                     /translation="MIEIIQPDSKQGIGTMKLENNYYELIRMHCSGTDSVFHLALRPDC
                     EIYRGHFPGTPVCPGVCNIQMIKECVERLTGCRLHIGSIHRCRLTAVATPMACPELSVK
                     INLQPTENGFAVTATVSDSRRTYMDYKGEMTV"
     CDS             complement(19184..19609)
                     /locus_tag="ctg22_301"
                     /transl_table=11
                     /translation="MKSGDIKDLLPQRAPILMVDELLEVNGEEAQTSFAVHPGNFFLDE
                     EGRLEASGVIEHIAQSASAFAGYTALLTGATKPPVGYIGEVKDFRCHHHPQVGEELRTT
                     IRLGAEAGGIILLSGKTCVGKETVAETQMKIFIQPND"
     CDS             complement(19606..19854)
                     /NRPS_PKS="Domain: PP-binding (9-75). E-value: 2.5e-14.
                     Score: 45.5. Matches aSDomain:
                     nrpspksdomains_ctg22_302_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_302"
                     /sec_met_domain="PP-binding (E-value: 1.4e-13, bitscore:
                     45.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRENIVAQVNSLLAEEFEVEATSFEPDANVKDTLNLDSLSLVDL
                     VALVQQTYKVKIPVTELRTIQTFNNLYDYIESHLPKK"
     aSDomain        complement(19630..19827)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_302_PP-binding.1"
                     /evalue="2.50E-14"
                     /label="ctg22_302_PP-binding.1"
                     /locus_tag="ctg22_302"
                     /protein_end="75"
                     /protein_start="9"
                     /score="45.5"
                     /tool="antismash"
                     /translation="VNSLLAEEFEVEATSFEPDANVKDTLNLDSLSLVDLVALVQQTYK
                     VKIPVTELRTIQTFNNLYDYI"
     CDS             complement(20001..21227)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (62-405). E-value:
                     5.7e-47. Score: 152.4. Matches aSDomain:
                     nrpspksdomains_ctg22_303_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 287.2; E-value:
                     3.7e-87)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_303"
                     /sec_met_domain="APE_KS1 (E-value: 5.8e-146, bitscore:
                     480.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENRVVITGMGIWSCLGTTLDEVRNSLYAGRSGIILSQERKAAGF
                     RSALCADIPRPDLKPFVSRNQRQFMPEEAQYAYMATRQALENARLDADYIDRHEVGLIY
                     GNDSVAEATMHALDKFRELGDTAACGSGAIFQSMNSTVTMNLACLFRLRGINLTASAAC
                     ASGSHSVGLAYLLIRDGLQECVVCGGAQEANMYGVAAFDGIQSFSVREAEPTRASRPFD
                     RDRDGLVPGGGAATLVLESYKHAVRRGASIWGEVVGWGFSGNGDHISTPNVDGPACSLE
                     LCLKNSGITPDEVGYINAHATSTRIGDSREAQAIARIFGERSVPVTSTKSQTGHEMWMA
                     GASELVYSMLMMKNDFIAANLNFENPDEETAYIHVLPERRETHFDLFLSNSFGFGGTNS
                     TLIVRNVRK"
     aSDomain        complement(20013..21041)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_303_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="5.70E-47"
                     /label="ctg22_303_PKS_KS.1"
                     /locus_tag="ctg22_303"
                     /protein_end="405"
                     /protein_start="62"
                     /score="152.4"
                     /tool="antismash"
                     /translation="SRNQRQFMPEEAQYAYMATRQALENARLDADYIDRHEVGLIYGND
                     SVAEATMHALDKFRELGDTAACGSGAIFQSMNSTVTMNLACLFRLRGINLTASAACASG
                     SHSVGLAYLLIRDGLQECVVCGGAQEANMYGVAAFDGIQSFSVREAEPTRASRPFDRDR
                     DGLVPGGGAATLVLESYKHAVRRGASIWGEVVGWGFSGNGDHISTPNVDGPACSLELCL
                     KNSGITPDEVGYINAHATSTRIGDSREAQAIARIFGERSVPVTSTKSQTGHEMWMAGAS
                     ELVYSMLMMKNDFIAANLNFENPDEETAYIHVLPERRETHFDLFLSNSFGFGGTNSTLI
                     VRN"
     CDS             complement(21266..22402)
                     /locus_tag="ctg22_304"
                     /transl_table=11
                     /translation="MKEVMINKVRTKQEMNDFIQLPRRLYAHCPQYVPDLDSDIRETFD
                     PRRNAGLEYSDIQPFVAYNDKGECVGRITGIINHRANEKWKTRNVRFGLIEFVDDPDVS
                     EVLLKAVEAWGRERGMTHIQGPMGIFDFDKEGMLVEDFDQMSSMITIYNPSYYPRHLEA
                     LGYRKEVDWVQVRIDVPQEVPDKYARVARLTKEMFGLKVRKLTDEDVYRRGYGRKVFEL
                     LNLAYCPLFGYTELTDKQIDSFLRRYLPLIDKRMLPVIEDESGQLVGVTITMGSLSHAL
                     RRSHGRLLPFGWFHLLRALKWKHEDKVEMLLIAVHPDYQGLGVNALFFDDLIPVYNELG
                     YRWAETGPQLESNVRELSQWKPLNPTVTKRRRCYTKEL"
     CDS             complement(22380..23312)
                     /locus_tag="ctg22_305"
                     /transl_table=11
                     /translation="MDNVSKVGFGQKHIPCEEEYMDNDIIFLNGIKDLPMADGVLRVDR
                     FVSVICYTGKLQVDINMATHTICAGQVLICIQNDIIGNAMQSPDFDGAVLSLSPGIIIN
                     QFGESNIWDYFFHLTDHPIINAHAENLEMLRIFYKAFSRKMRMGQTVFGKKIIFSIVKA
                     VFYELMENILPPSSSSCVKGPRRGKILLKQFMELLSGSVVKSRTVLWYAEQLCVTPKHL
                     STVCKQVSGKTAFEWINAYVAIDICNLLKNTDKSIKEISDILRFPNTSFFGSYCRKHFG
                     MSPMEYRKFLRTSTSENENTGQYERSNDK"
     CDS             23372..23563
                     /locus_tag="ctg22_306"
                     /transl_table=11
                     /translation="MLCPKIPQKQRIIPGWKNKTIYTLFGTGAVYPICSFREYSDIKLV
                     TYTHIGLTFIVSMFKYIP"
     CDS             complement(23509..23718)
                     /locus_tag="ctg22_307"
                     /transl_table=11
                     /translation="MVKYARVKEEDSGPSCSLAEALEKQDLFINSTLAQLGCNILWKMF
                     RNGMIEHHGIYLNMETMKVNPICV"
ORIGIN
        1 cgggcaggaa tggctgccgt attcgatggc atcaagcaaa cagactatcc tccgactctg
       61 ctgacgctca atgatatgga gcgaatgggg aataccgtat ggctgaaata ctgcattaat
      121 aagtaggagg acagatgcta attaataaaa tcaaaaaggg tatttctctt tttactgttt
      181 tttgtttgct cacaatggca ttgccttttt tgagctgctc tgcatctgca aaaggtgaac
      241 aacaatcaga aaaaacaaat atgaaaacat tgacagtcta tttttctttt acggcaggca
      301 atacgaaacg tatcgcagag agagtgcatt ctgccgtagg cgatgatata gtcaggctag
      361 agcccatgaa gccatatccc aaaaactatg cgcaggccgt aagtcaaggt gacgatgaag
      421 taaaacgtgg ctacaaacct gagttgaaac cgttaggtgt ggatttgaac aaatatgaca
      481 ggattatcat tgggacaccc acatggtggt atcacatggc tccggttgta ttgtctttcc
      541 tgtcaagcaa tgattttaca gggaagaccg taattccgtt tatgaccaac gcgggctggc
      601 ccggttctgc gattaaagac atgacagcct tggcgaaaaa gcaaggagcc aaagtggaaa
      661 acggacatga gttcaggttc agttccaacg aaaagcatta tgacaggatg gagacatcag
      721 agaaagagtt ggacgaatgg attgacagtc tgaaataatc cggtatagat ggatacaaat
      781 aagttgaaag gtcatgttgc cattctttct gccaatgtca tatatggtct gaacataccc
      841 gtgacaaagg cactgcttga caagtggatg acaccatggg gctatatggc gacacgcacg
      901 ctgactgcat tgcttatctt ttgggtgata caatgtttca cgccaaagga acggataaca
      961 cgccgtgacc tgctgactat cgccataggc ggcatcatgg ggtttgttgt atcacagttt
     1021 ctaacggctc tcagcctgca atataccagt ccggtttatt tctcattggt tatagcccta
     1081 agcccattat gtgttatgat gctcgcagca ttgttactga aagagcctgt aaccagacaa
     1141 aagtcagttg gagtggtgct gggaattgcc ggagcggtac tgctgatagc ttttgccgac
     1201 agcagtaatg cagacggaag taacaactta ttaggaatag ggttggcttg tgtcagcatt
     1261 ttcgcctatt caatctattt gattatcata cgttcagtgg cacagaaata tagtgcggtg
     1321 actcaaatga agtggatgtt cctttttaca gcaatcatac ttgtgccgct tggcgtatac
     1381 gaatatccgc agcaagctat tttcagttcg gaatgtgatt ggagcggcat acttgaactg
     1441 ggattcgtaa tcatcttctc cacatcactt ggctattttc tgatgccttt cggtatgaag
     1501 tatctgcggg caacgaccgt cagtgtatat atgaatctac agcccgttgt cgcgtcagtg
     1561 gttgccatct ttgtcgggca ggacaagttt tcgtgggata tgccgttggc cgcattgctt
     1621 gtattgacgg gggcttatgt ggtaagttcc agtcctgcaa gggaagaaca aagcaagaat
     1681 caagaaagaa caaataatca ataaaccaat aatcagaatg gcattatgag aaatgtaatg
     1741 atattgaccg gagccggtca gataggtatg gcgatagtcc gacgcatggg cttcggcatg
     1801 aaaatcatcg ttggcgataa gagcatgaac catgcagaga gcatttgcga cacgatggac
     1861 aaggcgggtt tcgacacttt gccgtttgag atgaacctcg cctctcgcga gtccatactc
     1921 tcattgatag acgaagcgcg gaagcatggg gaaatttcca tgttggtcaa tgccgcaggc
     1981 gtatcgccga gccaggcatc catagaaacc atactgaaag tggatttgta tggtacagcc
     2041 gtattgctgg aggaagtggg aaaagtaatg caagccggcg gtactggggt aaccatatcc
     2101 agccagtcgg gataccgtat gcctgccctt acacccgaag aagacagtct tcttgccacc
     2161 acgcccacta aggaattgct ctcactcgac ctcctgcaac cgcagaacat ccgcgacacg
     2221 ctgcacgcct atcagctggc taagcggtgc aacgtgaagc gtgtcatggc agaggctgta
     2281 agatggggcg agcgtggcgc ccgcatcaat tccatttcgc cgggcattat cgtcacaccg
     2341 cttgcccttg acgagttcaa tggaccgcgc ggtgacttct acaagaatat gtttgccaaa
     2401 tgtcctgccg gacggccggg gacagccgac gaggtggcaa atgtcgccga actgttgatg
     2461 ggcaaccagg ggacattcat cacgggagcg gatttccttg tcgatggcgg agctactgca
     2521 tcttactttt acggaccatt gaaacccaaa aacaaataag cgtatgaaac agttatcaac
     2581 agtctttgcc ttactgctca ccctctttag taccgtatca tgcgcacagg gaaagacggg
     2641 taaggcaacc aaaacattgg agacaagcag tatggaaaca ggaaagaaaa tattggtagc
     2701 gtttttctcg cacacgggcg agaactatgc cgtgggcaat atcacgaaag gaaataccca
     2761 cattatcgcc gaaatgatag ctgaatccac agatggcaaa ctctttgaaa ttgtgtccgt
     2821 caaggaatat ccgaagactt acaacgcttg cgttgaagtt gcgaaaaaag aaaaggaagc
     2881 cggtgcgcgt ccagcagtca aagacgacat agccgtggag gattacgatg tggtgttcat
     2941 cggctatccc aactggtggg gagacatgcc gatggcggtc tatacattca tcgagaggca
     3001 ccgctgggca ggtaaaacca tcatcccgtt ctgcacacat gaaggtagcg gactttccaa
     3061 tacggagaag tacatcgcca atgcctgcaa gggggcgaaa gtagaaaaag ggcttgccgt
     3121 aaggggcgca acggcgcaga acaagcagga gcaggcaaga aaagctgttg ttcagtggtt
     3181 ggaacgatta gggctttaaa atgtgtaaaa tgagaaagtg tcactttgag gtgcacaaag
     3241 tggcacttcg agaaaacaag ggtggcagcc tgttcagaca acagcaaaac ggatgcttgc
     3301 aaaggcatct agtgagacaa taaacatgat tcgttaaacc cattagaatg taagactaca
     3361 gaagcagcag ggtgtttact atccccaagc cattgtgcag ggcaagcccg tggaaacgga
     3421 gaccatcgcc aaggatttgg cgaaaatctc cacagtgagc aacagtgacg tgcaagccgt
     3481 attgggcgac atcacaggcg tgatgcacac gcgcatggcg caaggcaaga gcgtccacat
     3541 caaggggctg ggctatttcc gctacacgct cgacacggtg ggcgtgaaag accttgcgga
     3601 tttcgacttc gacaagcagg tgaagacggt acgtgtgcag ttcacgcccg aacgggagcg
     3661 gctgtcgaac aagacctaca cccgtgccct tgtggatagc gatgatttgg aatggattga
     3721 gctttctgcc gatgcgaagg atgatgaccc ggcgcagggc ggtggaaaca caggcggctc
     3781 cggtggtggt gaagacgagg gataatccgt taggataaac cgccgttcca tgcgattgcc
     3841 tgtaaatgga aaatgattgt gtgcaacccg taagtcaaga tgatttgcgg gctgcttgat
     3901 aaaaagaaag aataaatgaa actacatacc acaagtacag gatttctccg aacactgatt
     3961 tccgcaggct acctgctgat gtgcctgttg gcagtcggca tcatgtacct gtggtttcat
     4021 gaatggcaag agcttgaaaa gttggaaacg ggaaacagac aaataaacgc tttccgtcaa
     4081 gaggtgcatc atgtttacgg agaaatgacc gggctttctc ttttgggcga aagcgtgttg
     4141 gaatgggaaa acaaggattt ggaattgtac catgtccggc gcatggaagt ggatagtctg
     4201 ctttgccgtt ttaggactgt ttatccggca aagcggatag acagtgtacg ccatttgttg
     4261 gaggacaagg aaactttgtt tcgtggcata gtgaacgtgc tggacgaaca ggtaagtttg
     4321 aaccggaaga ttgccgagcg tgttccagtc attgccgcaa gaagcgcaca agaacaaccg
     4381 cagaagccga aacgcaaagg tttcttagat ctgttcggca agaaagaaaa gccgaaacca
     4441 accaccacga ccaccatgct tcaggcgctg aaccgcaagg agattacaca gcagcaggcg
     4501 caaagccgcc gtttgtcgga acacgccgac agcctcgcta tgcgcaacaa cgaactgaac
     4561 cgccaactgc aatcgcttat cgggcagatg gacaggaaag tacaagaaga cttgcaaaag
     4621 cgcgaggtgg agataaccgc catgcgtgaa cgctcgttcc tgcaaatcgg aggactgaca
     4681 ggatttctgt ttcttctttg ggttgtgtca tacatcatta tccatcggga catacgccgt
     4741 attagaaggt acaagtcgaa gaccgtcagc ctgataaggc agctccatga atcggatatg
     4801 cggaactgat agccaacgga gaaaatgcaa tgtaggcgga acattatttg ggcaatatcc
     4861 gacaggcatc ctgcaggatg attgccatgt tgaacacgct gcttgacttt ttccggctgg
     4921 atagtggaaa ggagattgta aataccgttc cgttccgatt gcagggtgtg gcagatgctc
     4981 tatcggcgga atttattcca ttggcagaag ctaaggattt acgcctgacg gtggaatgca
     5041 atacggatgc tatcctcatg ggcgacaagg aacgcatcat gcaggtttgc ggcaacctgc
     5101 tttccaatgc catcaagttt acgcaagccg gaagtgtatc actccgtatg gactacaacg
     5161 gctgtgtact ttctgttgtg gtggaagata ctggtagtgg tatgaatgtg gaggaacagc
     5221 aacgcatatt cagtgcattt gaacgccttt ccaatgccgc cacacaagac ggtttcggat
     5281 taggcttgtc gatagtgaaa cgcatcgtgg atatgttggg cggtacaatt agattagaga
     5341 gcaagaaagg tcggggcagt cgtttcacga tagaattgcc catgcaaacc gctgatattg
     5401 ctgtcaccga gaagaagaaa gagcaagagc aatatcaaga gccttacatt gaacgtgcct
     5461 attcggtcat tatgttggat gacaatgaca tccttctttc gatggcaagg gatatgtatg
     5521 cccattacga catccattgc gaggtatgca ccaatatagg cgacctcatg gaagccatac
     5581 gcacagggaa ctatgacttg ctgattaccg acctgaaaat gccggaaacg aacggttacg
     5641 aggtgctgga agttcttcgc tcaccggaca ttggcaactc gaagaccatc tccgtggtag
     5701 tcgctacggc atcgggaagc tgcaccgagg gagaactgct ggcgcatggt ttctccgcct
     5761 gcttgttcaa gtcgtttggc ttatcggaac tgatggcagt gtctgaaaag tgcctttctt
     5821 ctttgcaatc acccaaggat gaataccccg acctaacttc attattgatg tatggcgaca
     5881 aggcggcaat gctcgacaag ctgataaccg aaacgggaaa ggatatgcaa gtgatgaaag
     5941 aagccggaga aaagcacgac cgtgaatcgt tggatgtgca ggttcatcgc ctgcgcagtt
     6001 catgggcggt aatccgtgcg gacaaaccgc tatggaaatt gcatcggctt ctgcattccg
     6061 acacggaatg taccgacaac gagatacggc gtgcagtgga cgctgtgttg gcaatgggcg
     6121 gcaagattat ggaacaggtt aaaagacaaa aggaggacga acgatgaaag tgattgtgat
     6181 agaggacaat cccgtgtata gcgattatgt ctgcaacctc ttgaagaaag gcggcttcga
     6241 caccgtgcag gcatatcggc tttctaccgc caagaaactg ctgttaaaag ccggagagga
     6301 agacatcgtg ctttccgacc tgcgtttgcc agatggcgag ggcatagacc tgttacgttg
     6361 gatgcgcata gaggaaaaaa gacaaccgtt catcgttatg accgactacg cccgaggtac
     6421 atactacggt tgaaagcatg aaactcggct ccgcagacta catccccaag ccgttggttg
     6481 cagacaggct cgttccactc atccgctcca tgcacaatgc acaggagcag agaaagtcaa
     6541 gccaaatccc gatattcgtc cgtcaaggag cggcatatca agaaattaag cggcgtgtcc
     6601 gattggttgc gcccacccgt atgagcgtac tgatattagg cgagaacggt acgggcaagg
     6661 agcatatcgc ccaacacatc cacacccaag gcaaacgtgc ggacaagcct ttcgtagcgg
     6721 tggattacgg ctcattatct cagacattgg cgcaatccgc cttcttcggg cacgtcaaag
     6781 gcgcactcac gggagcggac gcaaacaaaa tcggctactt tcaggaagcc gagggcggca
     6841 cgcttttcct tgacaaagta ggcaacctcc cgttggaaac ccaacagatg cttttgcgag
     6901 ccatacagga acggtgttgc cgttccatcg gagcaaaaga ggacaagacc gcagacgtgc
     6961 gcatcgtggc ggcaaccaac gaggacttgc tctatcgtct gaaagagtac acgataaccg
     7021 taccaccctt gcgtgactgc caagaggaca tcctcccatt ggcggagttc ttcctcgaaa
     7081 tctccaatcg ggaactggaa tgcgacatca aaggttttga cgcatccgca cggaaagccc
     7141 tgcaaaccga tccgtggccg ggcaacgtgc atgagttgaa aaaaagggta caggtggctg
     7201 ttctccatgc cgaatgtgac atgataaccg agaatgattt tgaactatgc accgaagacc
     7261 aacccgtttc taccgtcttt gccctcaaag acaccgaaca ggaaaaggaa cgcatccgcc
     7321 gcgcattgga acaagcgaac ggtaacagaa gcatcgctgc ccgtctgttg ggaataggat
     7381 gctcaacgct ctatcggaag atgcaggact atgggatgct gtgaccctgt tgcaagtctt
     7441 gcctttcact cctatgtaaa atcctcacag agagttaaaa agcagagatt tttaggcagt
     7501 tattagatgg tttgaaaaat aatttgtact tttgcatatg aagagttgtt tgacagtaat
     7561 gagcggcaaa acgctgaaat taagaccgct gccaagtcat tacctgaaat tttgaataat
     7621 ctcataactc tctcattctg aaatatctgc aaaaacttat cggatttttg tggaaaagac
     7681 tttcggaaaa acacatggca agggtctcag aattctcttt cggtaacgct taagtcgcct
     7741 gacaacaatc ggttttcatg tagacagaag ttacaaccgt tttctatcct atgactggaa
     7801 agcatgtttt gcatcactgg tgaaagcttc aaagtagcaa ctattcccgt agtacgagtg
     7861 ttctagccct ataatcaagg aaattgtact ccaagggtac cctccatacg gagtgaggat
     7921 attagagata aaaagtatcc aagagatatc actgggtctt gtagcatctt tcagctttgc
     7981 atttgaggaa ctacctataa gctttaaggc tgttggcgga gaacctgtaa actccggaac
     8041 ccggatgact tctcaccgat atggcttcat ggcagatatt gacaggattg cttcttttac
     8101 ttgttaatga ttgattaaaa gtgtttacat gctcataatc tgaattgaag tgaatgagaa
     8161 tgcagaaaga tcaaatgtac aagctgtatt tatccaaccg cttacctata ttcttaaaaa
     8221 gacaaaacca tcgtcatcct tacgccgttt ttctgaatgt ctgggtggtt gcggtaactc
     8281 aaccgccata cgtagtcgat gcgcaggaat ttcagaatat tctcgatgcc cacgcttacc
     8341 tccatgtagg gcgtgttacc catcatgtag gtgcatccgg gaaaacggta aagctcctcg
     8401 ccgccgcttg ccgccgggtt gttcttatct gtcaggtgtc cccacagtcc ccggaagcag
     8461 aagacctcgc gccacttcag cttcttgacg aggggcagac ggttgagcag attgccgttc
     8521 atatagtagg tgatgtccca tgaggcgtac tcgtcgttga tgaactccag ggcgttcata
     8581 ttggtgtacg actccggctg tatggtatag gttaagttgg cattaggcag aatcagtagc
     8641 ggccatggga ctttcgtcca aacctttccg gctttggcta tgatgtcgat atagccgaat
     8701 gctgaaaacc agaagcgttt ctgcatgccg atgtccgtgc ggtggtaatt atagtccgat
     8761 ccaaggaagt cttttttcgc cataacatgg ctggcgttga atatcagtgc gtcgaaagtg
     8821 atgggaatac gcaggttacg cgtctggtag aatttctcgt tgtgggcata gcggaagcgt
     8881 agctccaggg cggttatgtc gtagtgatcc acaagtatgg aagtgccgtc cgccccgatg
     8941 cgctcgaagg cggcgtaggg ggtggcatac tcgcgacggt tgcgcacgac ggcattgtag
     9001 gagatgccgt tgtagtgctc ctgcgtatag gtcagttccg cctgtcgctg gtaggagatg
     9061 aagcggtcct tcttgcgacg tatcatcagc atcatgttgt ccttgctggt gtacatgtac
     9121 tcctgcccca acttgttgat gtcgtacata tactccagcc gcagggagtg catggggaac
     9181 tccttgcgga actccttccg ctcgttgaag gaatattcaa cgagggcgtc gtatttcagc
     9241 ttctcatcat ctacgccata tgccagataa ccgtcgagga acagatgttt gctgaaagcg
     9301 gtggtcgtgg ttccgcccac gcggaagcgc atcccctcca acgtgttgtt attgacggtg
     9361 gagttcatcg gtccgaactc gaacttgctc ttgtcctgtt cgcggtgcgt ggggacgtaa
     9421 ccgttgaaaa ggatggagag tgtcttcatc gtgatgcggt aggtaggtac ggcgttcagc
     9481 ctcgccatca ttttctccat cgagttggaa ttgcgcttgg cagcctcttc cgggcggtgt
     9541 tcttcccaaa aatcatccgt ctggcggtgc gagccttgca gggtgatgac gggcgcactc
     9601 tccttgaaga cgtgcatctg ctcttcggcg ggcggctcga aggagtggtt ggtataaata
     9661 tttagccgtc gggcatacat acccttcgtg cgttcggtca gcttaaagct cacgctgatg
     9721 tcgtctttcg tgatgatgcg cgtgctgtcc gccgtgcgct cgaactcctg cttgatggtc
     9781 aggcgggaaa cgaagttcaa gttgatgtcc ttgggcacgt tcagcacggc acgctgcacg
     9841 aagtaagtgg agtcgagcgt gacatatagg tgtccagtga atccgaaggt ttccgagttg
     9901 aagggcacga agccgaggtc cacgcattgt ttcccgttca cctgaagcgt gtccatcagg
     9961 tagtatttat agtagttggg accgatggaa gatagcggac tgacgaagcg ttgcaagaag
    10021 agcggaatgt cgttcttgaa aatgtccacc tcacggaaca cctcgccgag gaactgctgc
    10081 acgccgtcgg aagagaatat ctcgtcaatg cccgatgact tgaagccccg caccacttgc
    10141 ttctccgacc gtggttgccg acggtaatag accgtctgca ccttctcctt ctccgataca
    10201 ggcaggatag tgatgccgtt gtccaatgta tccacgaact cctccaagaa gtcgaacttg
    10261 cccgccttcc cctctttctt ggacttgtgg acatattcgt tcttggcgaa aatcatcttc
    10321 tcatactggt cgtaactgaa gtagtcgtgg ttccggggat tgctctcctt gcgtgattcg
    10381 ataaggtggc gcacgaactc cacggcggga ttctccttct tgcggtactt ctcgcgccgg
    10441 ggcttgacgg tcacttcgcc caaggcgatg ccggtaggtg ccaggcagat gtccagtaca
    10501 aggtttttcc ctttcggggt aatgcgacat tcgcggcttt cataacccag ataggatatt
    10561 tgtaacatgc cgggtgtatt ggggacactg aacaagaatc gcccctcacc gtcggttgcc
    10621 ccgcctaccg ttgtcccctt cagtatcaca gatgcgtatg gcaatgcctc acccgtgatg
    10681 gagtctgtca ccacaccgct gatttgcgta tgctgcgctc gtgccgtaca taccacaatc
    10741 aggcatacca gccaaagtat cgtctttttc ctcattacaa tcttctttct tctgtttttt
    10801 taccttgtga acaatcttat aactctttgc gtaattgcct gcacatccgt tcgtgtctct
    10861 ggcgcatata gcggcacagg ccacccatga caaatatctc gaaaaagaaa taaagccagg
    10921 ggacatcggc aaggcagacc acatagagtg cgatggcgcg ggtgttgaac gtcaggacgt
    10981 tcgcccattt catcagcggg agcgaaagcc tgcggaaacg gtcacggaac ggctgcggta
    11041 tgttctctgt tgcaccgtat cgttcgcaca accgctgcat cagccgttgg aactccggtg
    11101 tctgtgactc ctgtgtccgg gtgtagttca cgtaggtctt cagaaaagct ttccacagac
    11161 ggttgtcctt ccacggtgtc tcatcataga gccgttgctg ctgtgcggag ttgtccagct
    11221 cactgccagc ctccccattc aggaagaaaa ggtgtatctg acggtaatag tcggcaagcc
    11281 cgcactggcg gctgtggcaa tggaagccgg aatagagcac catgccaagc agcagcaagg
    11341 tggctatcca tgtgttctgt gccgtatctg caatgccaag gcaccggaac tcccatccgt
    11401 gatgcacgta gaaccgatag acaaggctca ggtagatagg tatgaaccac acctcgctgg
    11461 ccgccccgtc aagaatgcgt cccagacggg tctttttgcc agtcatgcgt gccagctgtc
    11521 cgtcggcact gtcgtaaaag ttcgcccatg ccagcagcag gacagcgaca atgttgagcc
    11581 acaggccgtt catgccttcc gtgcggtaag aaccatgggc aaagaacaat gccgaacttg
    11641 caccgattat catggagagt accgtcaccg tgttggggtg tattctcagc cgttcgaaca
    11701 ggcgtgccca ccagtaaccg ataggacgtg tccatacccg gtcaatccat tcttccgtat
    11761 cattggactt ataagtcgat ttaatgtttt cctttgtcat aatcatgttt tgtttgtagt
    11821 ttcattacga ttccctgttt tcatcagcag cagaccaacg gagcaccaga acagctcccg
    11881 cacacggcag atgatactga taaacatggc cgttccaccg gtcatgccca tctgtgccac
    11941 agacatggca aagcctccct cacgcccgcc caattgcagg ggcaggaaac cgagcaggtt
    12001 ggcaaagagc gacgtgaacg caagaatgag aaatgaatgg aggaatgtca gcagataacc
    12061 gtctgtacct ccacctccgc ctatccccaa aagccttaac atgaagaata tctcaaaact
    12121 ttgcagcaac cgtcccgcat attccaggat gaagctgccg aagaacgagc gtttgttctg
    12181 cccgtgcagt tcggaaatct gccggtctat cttttccaga tcttcccgat ggctctcgga
    12241 gaaacgtttc tcccatcggc gcaatccggg caccctgccg atgatccgca tcagctttac
    12301 cgccattcca tacttgtatc cacggacaaa gaggcagatg cctccaccac agaacagcat
    12361 cgccagtgcc aataccactc ccgttgcggt gttcaacggc aagtcgccgc tgaaggcaag
    12421 tacaaggtaa acggcaatgc ttgttaccca gaaccagaaa tggcagaaca cgtgcatcat
    12481 gacaaaaagc actacggaag aggtggcacg ccgggtgtcc atgtacctcg acagttccat
    12541 gatgcgatat gtctcaccgc ccaccatgcc catcggcgtg gcatagttca gggcaaaccc
    12601 cgtgacggtc agtttcaaca accgccaaaa gcttatcgta caggagccac tgccacggat
    12661 gatgatctgc catgcccatg tgttcagtac atagagcagc atccacaacc ccaatatggc
    12721 cgccagccaa caattcgccc tccggatgta tgcccactgt tctgcgaaac tcacgtcgaa
    12781 cgtgcagaac atcacgacga ccgccgtaat gccgacggca aagaacaggt tgttgatgcg
    12841 tttcctcata tttctgtttt actccctatt tccaaatatc tctcctgcca ttccctgtaa
    12901 taagcgggtt tgtctgtcag aagttctccg tcagtaccga taaacaattg tgtgctgctg
    12961 ccttccgcac agagtacatc gtcactttcc ctgtatatcc ggtaggcata gtctaaccgt
    13021 gctccccgat gatagacgta gagggtgtgt atcaccgcca catcattcat agccagtgga
    13081 gccagataac ggatatgcag gtcataaata ggagcataaa cacccgccat ctgcatatcg
    13141 gcatacccga tgccgggcca gtgccgcccg aacgattcgc gcccgtcctc catgtaggtg
    13201 acaaacgagc catgccatac acgccgcatg gaatcaattt cactgaaccg aaccggtatg
    13261 cggcaaatgt cttcaagcgt cttcatccgg gtgctcctta catcacggtc cgggtgtcga
    13321 acacgctgtc gcttacttca gcatcgaaca catagttgga gaaatcatac tgcgtatagt
    13381 tctctccctg ttcgttgatg cgcaagctgc gcagttcggc ggctttcagg tcgatagtca
    13441 ctatacagga ggtgaacatg ctccggcgtt tcgccttcgc atcggttgcg gtaggcgtga
    13501 tggtgattat gctggtattt ccctgtgtct ccaatttcac gtccgccatg tcggtcagct
    13561 ggacatcgtc gtctgccgaa agcaggttgc ggaacacgtc ctgcaagatt tcaaacgggt
    13621 tgttgccttt tcctttggtt ttggcaacat gttgtttacc gtcctttacc atgacaaaag
    13681 tgttgcttac ggcaatcagc atctccccgg attccttgaa caccatgctc tgattgttcg
    13741 gcttcttgta atagaaatgt ccgtcggtca ccatgtcttt ggtcaaagcc gcgttatgct
    13801 tggtttgctt tacattcgtt atcagcgtat tggttttcgt atacctttcc gctgtcttgc
    13861 ggatgtccgc ccgttgcgcc gatatgccgg tgcagacgaa gagggcggta ataaataggg
    13921 taaacagtct tttcattgct tctttgttta atggataata tttagttgac gagttgacaa
    13981 ggcttctggc aacaaggacg tttccggtcg ctgacttgta gtctgttccc ttatcaactt
    14041 gtctacttgg caactctaag tgtaaagtcc tccgttgatg gaaatcactt cccccgtaat
    14101 gtaggctgcc tgtggcgagg caaggaagcc taccagttcc gccacctctt cgggcgtacc
    14161 gaaccgtaag gcggggatag tattctttaa tgccgccgtg tccaacccct ctgtcatgtc
    14221 cgtctcgata aagccgggag ccacggcatt cacggtcaca cgcttgcgtg ccacttccag
    14281 agccaaagcc ttggtggcgg caataaggcc ccccttggca gcagagtaat tggcttgtcc
    14341 ggattgtcct ttcaagccgc tcacgcttgt cacattgatg atacgtccct gcttatgcac
    14401 cagcatgggt tgcaatacgg cctgtgtcac gttgtagaaa ccgtccaatg taatgccgag
    14461 tacccggtgc cagtcttctt cgggcatgaa taccagtaca ttgtcacgac ggatgccggc
    14521 attgttcacc aatacctcga tatattcttc cgggtggtcg ttctcccaca attcgatggc
    14581 ctttctcact tgctcacgtt tgctcacgtc gaacatcagt atctcaccat cctgcccagc
    14641 ctgacgtacc aattccaatg ttttctgagc ctcggcagcg ttgcttacat agttgataag
    14701 aatgtcatag cccatccgtg ccagcttgat gcagaccgca cggcctatcc cgcgactgcc
    14761 tccggttact aatgcgtatt ttctcattat catatttatt ttaattttcc atttatttca
    14821 tttcctatga ttccccatat cgtttctttt cccaatacct cagcacaggt atggaatgcc
    14881 gtcatggtca ctccatgaac tccgtgcagc atcaggtttt gccctgtcaa caacaagttc
    14941 gggacaggag tacgtggaga cagcatcgtc agcagcgggt cacggaaatc cttccggata
    15001 ccgtaggcac taccttctgg tgtcaaagta taatcacgcc aggtgatcgg tgtgctggtg
    15061 tagcatcgcg actgctccct gagtccgggc agaaaacatt cggcaagttc gatgcactcg
    15121 tccgccatac gtttcttcat tgccttgtag tcactgtcac gcttgcccgt ttgcgtgtag
    15181 ttccatgatt tgcattgttc ccacagcatc ggggtaagca aatccacttg tccggtatat
    15241 tcacttccgt cctccggtac ccgacaactg acaagtacac ctcctacgca ggtattgtct
    15301 tggtagaaat cccacatgtt cggttcgcgg tagatgtagt ggttgtagtt gaagtagcgt
    15361 aaaccacgtg gtcggatgcg gagtgacacg gtaaacatgc cgaatgtatt ctccagattg
    15421 ttgatgcggt tgcgataagc agattttatc aggttgcttc gtctgagcaa tccacaggtc
    15481 tgtgccggat ggatgtcact gatgaataaa ccgccttcat atctttcgcc gttagcacaa
    15541 actgcacatg tcagtttccc gtctttctcc accagttcct gtactttggc gttgcagatt
    15601 atttcaccac cttgtgcata aattccctcc gccaatgatt ttataatctg cgaaccgtcg
    15661 cctttcaacc tccaactgct ttcaatgaaa cttccgttac catgcaggaa agtgaacagc
    15721 ggaagcgatt ccttccgcag ttccattttc agcgaagtgc cgctcagtac atttatcagt
    15781 agcgggttgc ggatattttc tttcagatag tgccatgcac tcgttgccat cagttcggat
    15841 gaaaaggcag ggaacccgtc tgcatgagga ttaagggcgg caaactgccc ggccgaagaa
    15901 cgttttaaca acttcgcata acgtcgtaag gcaatacgtc cggacgggaa ttcctctgca
    15961 agctgccggg caaaatcgtc atacccttcc acaaaagcaa aggtgcgtcc gccgatgctc
    16021 actcgatcga aaccgtcggc atccaaccga tgccaaggca agtccagcaa gcccagatat
    16081 ttgaaggctg cgtgcagcga ttgtccctca tccaatccgc ccacatagtg aaaacctgta
    16141 tcgaaggtca gttcacgacg acggtagttt tgcaagcaac cgcccggcac ggcaccctgt
    16201 tccagcacca gcacgcgctg tccgtgacgg gcaagaatca gtccacattc caatccaccc
    16261 aatccgctgc cgataatgat tacatcgtac ttcatgcctt tcctcctttc ttgtttatcc
    16321 aaccgtaaac ggcaggctgc accacatacg aaagccctac cgccgacacc agccctacca
    16381 gtgtggagaa accaacggaa cggatagctg gatgttcggc aaagagcatg gagccgaccg
    16441 tgacaatcag ggtaacggca ctgaagaata tcgccgtctt gtgataagcc agcaaacggc
    16501 tgtccttttc accgcctata agcccgttca tcacgaagat actgtaatcc acaccgatac
    16561 cgaagataaa ggtcgaaatg atgatgttta tcaggttgaa cctcatgccg aagatggtca
    16621 tagccccaag gacaatcagc caactcagca ggataggcag gaatgcgagc agggtatgtt
    16681 tcagattgaa acggaaactc accagcaaga ccacgaaaac aaacagcatc gacacccatt
    16741 gtagcacgtt gaaatcctcg ttcattgcgg tcagcgtgtc ggtcgtataa taataggtgt
    16801 caagcaccat cagattgggt tcggtgacta tggcatcgca aatgcggtaa tagtcactca
    16861 tatggctgcg caccgtgtcg ttagcacaac gcacggaggt aaagcatagg tgctcgtcgt
    16921 tgtaggactg ctccattagt gtggaccagt agcccggcgg gatgatgcca gctttgtaga
    16981 gtgcatcggg ttcgtagtct gccgtggcat aatcgaaaaa cggttcgaat gcttccgggc
    17041 gcagtccggc ttccggtgcg gtggcggcaa tcaggcggcg cacttgctcc aaccgttcgt
    17101 ccgtccaata gcgtttccat gcctccattc gctcctgctg cacccgcagg ggaatgaaca
    17161 gcttgtccgt gtgcgtatag ttcttgacca gcccgatgcg ttgcatggag tcgagcttgt
    17221 gcgacagcag ggcgaaacgc tctatcgctt cctccatcgt ctgcccggaa gcggcaaaat
    17281 atttctgctt gtcggcggta taggtctttc ggagtagtag gttttcggag taggtggtac
    17341 gctctgcctt gtaccctaag ttgtgcatat ccgcatcgaa ctgcgtgcca cacgccacgt
    17401 agcagccgat gcagacgaac gtgacgacag cgattccagc cagcaaccct ttcttgcgat
    17461 ggaacggata ggcattgata cggtcgatgg cggtgaaggc gcggtggttc atgcggttct
    17521 tttccggacg cagcagccca ggtaggtagg tgaggctgaa tgccgtggta cccgtgatgg
    17581 cgaaggcggc gaacaaccca aaatcctgca acaaagccgt atcaatgaag aacagtccca
    17641 tgaatgagcc gatggtggtg aggcatccca ggcagaccgg cttcacctgc tcgcggagca
    17701 cctgttcggg attgcctaca tacttgtaat gtgtcagcac atgtagtacg tagctcatcg
    17761 ctacgcccaa gaccacagcc cctatgccca aggcgagcag cgagaactcc cctttgagga
    17821 aatacatcat cgccagtccg aacaacgtgc cgaatagcac gggtagcagc aggagtggca
    17881 atgtgtcgcg attgcggaaa cagacgcata ggaaaagaag taccagcagg agcgatccgc
    17941 cgatggtacc cgtcaggtca tgcttgattt gcgaggcgtt gtagaagccg ctggccggcg
    18001 tgccgtggta acagatgcgc acgtcggggg cggtctcgga aaattcgtct gtcagtccgt
    18061 tcagcaggcg gaacaaggag gaaccctgcc ccgtgttggt ggccgaatag cggggtgtaa
    18121 ggaatgccac gcataccgtg gagtccggca cgaaaaaatg tccgtcgatg gtgtggtagc
    18181 cgcccgtacc gcccttggcc agcggcttca tctgttccgc caacaggttg cgcaggccga
    18241 tggggtcagc ctgtatcagt tcggggtaca tcgagccgaa gtcgcccgtc aggtcaatgc
    18301 ggttgcgctc catctgccgt gtgaaatgct cctgtgtcag catcgtgtcg atgcgggcat
    18361 agagggaagt gtctatgtag gcaggcagat gcccgctgag gtagtcgatg gcatcgggca
    18421 gtaagtcgtc ggacagacgg tagaacacat cacctaccga cccgtgtccc tcaccctgtg
    18481 ccgcatcgcg cacctgcaaa gagtcgatga atgcatcgca tacctcgatg atgcgctccg
    18541 tggaagcacc gtccaccccc tcgaaaagca ggaaagtctt gtccttgatg cgcaggttgg
    18601 caaaggcgag tttcgtactg ctgtcctcgt tgcgcgacga tggcatcagt ttgttcaaat
    18661 cctcttccaa atggatttgg gcggcaaagt agccgcaaaa gaggaataac cccgccagcg
    18721 aaaaccaata gagtgcgtag tggcggcgga aatagcggta gatgcgaatg caaagttcag
    18781 tcatacagtc atctctcctt tataatccat gtaagtgcgc cttgagtcgc tgacggtggc
    18841 agtgacggca aatccgttct ccgtaggctg caagtttatc tttaccgaca gttctgggca
    18901 agccatcgga gtagcgacag ccgtcaggcg gcaacggtgg atgctgccga tgtgcaaccg
    18961 gcatcccgtc aaccgctcga cacattcttt aatcatctgt atgttgcaga caccgggaca
    19021 cacgggggtt ccgggaaaat gcccgcgata aatctcgcaa tccgggcgga gggcgaggtg
    19081 gaacacgctg tccgtcccac tacagtgcat acggattagt tcgtaataat tattctctaa
    19141 tttcatggtt cctatacctt gtttactatc cggttggata atctcaatca ttcggttgga
    19201 taaagatttt catctgcgtt tccgctacgg tttcctttcc cacgcaggtc ttgccggaca
    19261 gcagtattat ccctcctgct tccgcaccca atcggatggt ggtccgcagt tcctcgccca
    19321 cttgcgggtg gtgatggcac cggaagtcct tcacttcacc gatgtagccc acgggaggct
    19381 ttgtcgctcc ggtaaggagt gccgtgtatc cggcaaaagc cgatgcggat tgtgcgatat
    19441 gctctatcac cccgcttgct tccaaccgtc cttcttcgtc aagaaagaag ttgccgggat
    19501 ggacagcgaa ggaggtctgc gcctcctcac cgtttacctc cagcaactcg tccaccatca
    19561 ggataggggc gcgttgtgga agcagatctt tgatgtctcc gcttttcatt tcttcggcag
    19621 atgggattca atgtaatcat acaggttgtt gaaggtctgg atggtacgca actccgtaac
    19681 aggtatcttc accttatatg tctgttgcac cagtgcaacc aaatctacca ggctcaaact
    19741 gtccaggttg agggtgtcct ttacgtttgc atccggttca aaagaggttg cttccacttc
    19801 aaactcttca gccaacaggc tgtttacttg tgctacaatg ttttcacgtg tcataacttt
    19861 gtttttatac aatgattaat attctgtttt ttggtgttat aagaacttat aggaagttat
    19921 cagccaacaa gctggcttca agaagttaga ggtcaatagt cttgttgtca aaagcaaagt
    19981 atcgaccttt aacttcctcc tcacttcctt acatttctta caataagcgt cgagttcgtt
    20041 ccgccgaagc cgaacgagtt ggagaggaac aggtcgaaat gcgtctccct gcgttcgggc
    20101 agtacatgga tgtacgccgt ctcttcgtcg ggattctcga agttaagatt ggcggcgatg
    20161 aaatcattct tcatcatcag catcgagtag acaagctcgc tggcacccgc catccacatc
    20221 tcgtgcccgg tctggctttt ggtggaggtg acaggtacac tccgttcgcc gaatatgcgg
    20281 gcgatggcct gtgcttcgcg gctgtcgccg atgcgggtcg aggtggcgtg ggcgttgata
    20341 tagcccacct catcgggcgt tatgccgctg ttcttgaggc aaagttccag tgaacatgcc
    20401 ggaccgtcca cgttgggcgt agagatgtgg tcaccgttgc cggagaatcc ccagccgact
    20461 acctcgcccc atatcgacgc cccccgccgg acggcgtgtt tataactttc gaggacgagg
    20521 gttgccgcac cgccgcccgg taccagtccg tcacggtcgc ggtcgaaggg acggctggcg
    20581 cgtgtcggtt ccgcctcgcg cacggagaag gattgtatgc cgtcgaaggc ggccacacca
    20641 tacatgttcg cctcctgcgc accaccgcac accacgcact cctgcaggcc gtcacgtatt
    20701 agcaggtagg caagccccac ggaatgcgag ccggaggcgc acgctgccga tgccgtcagg
    20761 ttgatgccgc gcaggcggaa caggcaggca aggttcatcg tcacggtgga gttcatgctc
    20821 tggaagatgg ctccgctgcc gcaagccgcc gtatcgccca actcgcggaa cttgtcgagc
    20881 gcgtgcatgg tggcctctgc tacggagtcg ttgccgtaaa tgagtcccac ttcgtgccgg
    20941 tcgatataat ccgcatccaa ccgtgcgttt tctaatgcct ggcgtgtcgc catataagca
    21001 tactgcgcct cctccggcat gaactgacgc tggttgcggg agacgaacgg tttcaagtcg
    21061 ggacggggaa tgtcagcgca caatgccgag cggaatcctg ccgccttgcg ttcttgactg
    21121 aggatgatgc cactccgtcc cgcataaagc gaattgcgca cctcgtccaa tgtcgtaccg
    21181 aggcaggacc agatgcccat gcctgtgatt actactctgt tttccatatc ttctgattaa
    21241 attttaaatt cttcattctt tattttcaaa gttcctttgt atagcaccgt ctccgtttcg
    21301 tgaccgttgg gttcagaggt ttccattgcg acagttcccg gacattgctt tctagttgcg
    21361 gcccggtctc cgcccaacgg tagcccagtt cgttatagac cggtatcagg tcgtcgaaga
    21421 agagggcgtt cacacccagt ccctggtaat cgggatgcac ggcgataagc agcatttcca
    21481 ctttgtcctc atgcttccat ttcaaggcac gaagcaggtg gaaccagccg aaaggcaata
    21541 accgcccgtg cgaccgtcgc aaggcgtgcg acagactgcc catcgtgatg gtcacaccta
    21601 caagctggcc ggattcatct tcgatgacgg gtagcatccg cttgtctatc agtggcaggt
    21661 aacgtctcag gaacgagtca atctgcttgt ccgtcagttc cgtgtagccg aacaagggac
    21721 aataggcaag gttcagcagt tcgaagacct tcctgccgta gccgcgcctg tacacgtcct
    21781 catccgtcag ttttcttact ttcaaaccga acatttcttt cgtgagccgt gccacgcggg
    21841 catacttgtc gggaacctcc tgcggcacat cgatgcgtac ctgtacccaa tccacctctt
    21901 tccggtagcc caatgcttcc aaatgtcggg gataatagga agggttgtat atcgttatca
    21961 tggagctcat ttggtcaaaa tcctccacca gcatcccctc cttgtcgaag tcgaagatgc
    22021 ccatcggtcc ctgtatgtgc gtcatgcccc gttctcgtcc ccatgcctcg acagccttca
    22081 ataagacttc cgatacgtcc ggatcatcta cgaactcaat caggccgaag cgcacgttac
    22141 gggtcttcca tttctcattg gcacgatggt tgataatacc tgtgatacgt ccgacacact
    22201 cccctttatc gttgtaggcg acaaaaggct gaatgtccga gtattccaat ccggcattcc
    22261 tgcgtggatc gaaggtctcg cggatgtccg aatcgaggtc gggcacgtac tgcggacaat
    22321 gggcataaag acgacgtggc aattggatga agtcattcat ctcctgtttc gtccttacct
    22381 tatttatcat tacttctttc atactgtcct gtgttttcat tctcacttgt agatgtcctt
    22441 aggaatttcc tgtattccat tggtgacata ccaaaatgtt tccggcaata ggaaccgaaa
    22501 aaggaggtat tgggaaatct tagtatgtct gaaatctcct tgatggactt gtcggtgttt
    22561 tttaggaggt tacagatgtc aatagcgaca tatgcgttaa tccactcgaa tgcggttttt
    22621 ccgctcacct gcttgcatac ggtggaaagg tgcttggggg taacacataa ctgttcggca
    22681 taccacaata cagtacggga ctttaccaca ctgccggaaa gcaattccat gaactgcttg
    22741 agcaggatct tgccccggcg cggtcctttg acgcaagagg aggatgaagg gggaaggatg
    22801 ttctccatca actcgtaaaa caccgccttg acgatggaga aaatgatttt cttaccaaat
    22861 acagtctgcc ccatcctcat cttcctgctg aacgccttat agaatatccg tagcatctcc
    22921 agattctctg catgggcatt gataatcgga tggtcggtca aatgaaagaa gtagtcccat
    22981 atattgctct caccaaactg atttatgatg attcctggag acaaggacaa cacggctccg
    23041 tcgaaatcgg ggctttgcat ggcgttgccg atgatatcgt tctgaataca tatcaacacc
    23101 tgtcccgcgc aaatggtgtg cgtggccatg tttatatcca cctgcaattt acctgtgtag
    23161 catatcacgg agacgaaccg gtccacacgc aacacaccat cggccatagg cagatccttt
    23221 atgccattca gaaatatgat gtcattgtcc atatattcct cctcgcaagg tatatgcttc
    23281 tgaccgaatc cgactttaga aacattgtcc atactcataa tccgttgttt taccaatgaa
    23341 attgctacaa aagtaaccgg ttgccatgcg aatgttgtgt cctaaaattc ctcaaaaaca
    23401 acggattatt cccggatgga aaaataagac aatatacacc ctttttggaa caggggcagt
    23461 ttaccccata tgttctttta gggaatacag tgacattaag cttgtcactt atacacatat
    23521 cggattgacc ttcatagttt ccatgttcaa atatatccca tgatgctcaa tcataccatt
    23581 tctgaacatc ttccaaagga tgttgcatcc gagttgcgcc agcgtggaat tgatgaacag
    23641 gtcctgcttc tccaacgctt ccgccagcga acagctcggt ccggaatcct cctctttcac
    23701 tctcgcgtat tttaccag
//
