LOCUS       c00437_gnlPro..        14616 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CLIHEBLN_437.
ACCESSION   c00437_gnlPro..
VERSION     c00437_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 18:38:36
            Original ID  :: gnl|Prokka|CLIHEBLN_437
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14616
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14616
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3318:8379]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3319..8379
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14616
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14616
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(2..829)
                     /locus_tag="ctg437_1"
                     /transl_table=11
                     /translation="VADTKYIFVTGGVVSSLGKGIISASLGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLNVQTTRANNITTGRIYQSVINKE
                     RKGDYLGKTVQVVPHITDEIKRNVKLLGSKYKFDFVITEIGGTVGDIESLPFIESVRQL
                     KWELGKNCLCVHLTYVPYIAAAKEYKTKPTQHSVKQLQELGIQPDVLVLRTEHELNANL
                     LRKVALFCNVAEDSVIQSIDVPTIYEVPLVLQRQKMDEVVLRKVGMEVGPTPEL"
     CDS             1250..2791
                     /locus_tag="ctg437_2"
                     /transl_table=11
                     /translation="MMKRHGVYALLLLSLIGSSAYSQENQLVTGTIVQRPAQQVVSDDT
                     IPAINLGEEELDNIVDIRKQFEKQNKTYSAPLAPSTNLLRFLKKDELEISDEAMYWARL
                     VRDASTAFDNTMTFRDTVIVNPLFMPIVFRGDYLPKNLIFYNFDSLKERTPYDNLYRTD
                     SIFKDLERNKQFEEMAYKYVQNNYPTYFRYSERDLPNEVIKPKFIKKNIYEDLPIKVEA
                     DANFEDVDAPARFIPERRYWISAFESAVQFSQNYVSENWYKGGSSNLNLFTKNNLKYDY
                     KKDKVQVTNELEFKASVYTAPKDTLRNYKIGDDVFRIHSNVGYQAFNKWYYTFDAEFKT
                     QFFTNYQENERIKQAAFLAPFSINFGLGMKYELEKQFTDKHKKIKFSTNLAPISYTYMY
                     TTQEIDYSRHGFKKNEETGEFNNKLSQIGSTIRADLAFDFNRNVSWQSRLYFFTTYGDH
                     TIGEFENTLVLAISRFFSTRIYFHLRYDDGVEKTEDNKSYFQLNELLSFGFNYKW"
     CDS             2893..3309
                     /locus_tag="ctg437_3"
                     /transl_table=11
                     /translation="MSESINHTGFVEKIDGDTVFVRITQQSACSGCHAQSMCSASEKKD
                     KIIEVPDRSGRFHVNEEVIICGQNSMGLQAVLLAFVIPLVIVVGAIVIGTNLQWDETTS
                     GLTGLSLLLPYYCILYLMRDKLKRRFIFTLKKLN"
     CDS             3319..4251
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 35.6; E-value:
                     3.5e-11)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg437_4"
                     /sec_met_domain="Fer4_7 (E-value: 7.9e-12, bitscore: 35.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.1e-11, bitscore: 34.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 2.2e-09, bitscore: 27.1,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.6e-10, bitscore: 30.5,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-06, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILIAVISLGAIGAVGAVFLYAASKKFEVYEDPRIAQVQEVLPGA
                     NCGGCGYPGCAGFAGACVKADSLDGLLCPVGGGPVMAKVATILGKEAGTAEPMVAVVRC
                     NGTCQARPRTNSYDGTKSCAIASTLYGGETNCSFGCLGYGDCVNACAFDAIHINPATGI
                     AEVDEEKCTSCGACVKACPKNIIELRKKGPKSRRIYVSCVNKDKGATARKACANACIGC
                     GKCAKECPFEAITVTNNVAYIDYTKCRMCRKCVAVCPTGAIHELNFPPRKEAAPAPKAE
                     TVKPAPKAEATVKPEAAPKATSEEKTNLN"
     CDS             4263..5594
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg437_5"
                     /sec_met_domain="Fer4_10 (E-value: 9.6e-10, bitscore: 28.5,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 3.3e-17, bitscore: 52.1,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.5e-50, bitscore:
                     161.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 2.9e-32, bitscore: 100.7,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.7e-05, bitscore: 15.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRTFRIGGIHPPENKLSAGKKITALATPKQVIIPLSQHIGAPAQ
                     AVVKKGDLVKVGTLLAKAGGFVSANIHSSVSGKVNKIDNALDASGYKRPAIYIDVEGDE
                     WEETIDRSEALVKECSLSSKEIVDKIAASGIVGLGGATFPTQVKLMPPPGNKAEIVIIN
                     AVECEPYLTSDHSLMLEKGEQILVGVTILMKAVNVNKAVIGIENNKPDAIAHLQKLAVN
                     YKGIEIMPLKVQYPQGGEKQLIDAVIRRQVKSGALPISAGAVVQNVGTAYAVYEAVQKN
                     KPLFERVVTITGKAVANPSNFLVRMGTPISCLIEAAGGLPENTGKIIGGGPMMGKALIS
                     AEVPVCKGSSGVLLLTTEESVRKPIRDCIRCAKCVGVCPMGLNPTLLMNATEFQNWELA
                     EKNYITDCIECGSCSYTCPANRPLLDQIRFGKGKVMGIIRSRKS"
     CDS             5607..6575
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg437_6"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 6.7e-117,
                     bitscore: 379.8, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLYVSPSPHIHGGDSISKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTVVSVLACMIFEYLIQRFLMKKEPTLCDGSAILTGVLLAFNLPSNLPVWIIIIGAL
                     AAIGIGKMSFGGLGNNIFNPALVGRVFLLISFPAQMTTWPVVDALNVFPMTYTDAQTGA
                     TVLSLMNEGVTELPSYGNMLVGAMGGSLGEVSAVALILGLLFMLWKKIITWQIPVSILA
                     TVFVFTGIMHLVNPVQYASPFVHLLSGGLLLGSIFMATDYVTSPMSKNGMLVYGVGIGI
                     LTTVIRLFGSYPEGMSFAILIMNAFTPLINSYIKPKHFGGK"
     CDS             6608..7192
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg437_7"
                     /sec_met_domain="FMN_bind (E-value: 5e-26, bitscore: 81.1,
                     seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLSLTGICLVAGAILAGVNQFTAGPIAVAKATALEEAIKAVAPE
                     FDNKPTEDVYMAVSSDGDSLKIYPAKKGGQVVGGAVESNTKKGFSGEIRVIVGFDMDGK
                     ILNYSVLQHAETPGLGAKMQEWFRADKNKQSVLGRTIPDGGLKVTKDGGDVDAITAATI
                     SSRAFLDAVNRAYSAFAGVDGLTGATSTDNK"
     CDS             7210..7794
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg437_8"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.6e-69, bitscore:
                     222.6, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNLKILMNGIITENPTFVLLLGMCPTLGTTSSAINGMSMGLATM
                     FVLICSNIVISALKNVIPDLVRIPGYIVVIATFVTVVQMCMEAFVPALYASLGLFIPLI
                     VVNCIVLGRAEAFAAKNGIIPSALDGIGMGLGFTMALTLLGACREFLGTGKLFNVTLMP
                     EEYGSLIFVLAPGAFIALGYLVAIVNKLRKA"
     CDS             7807..8379
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg437_9"
                     /sec_met_domain="Rnf-Nqr (E-value: 1e-65, bitscore: 210.9,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFIAAVFVNNVVLAQFLGICPFLGVSKKVETAAGMGAAVT
                     FVLTIATIVTFLVQKYILDAFGLGFMQTISFILIIAALVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKEYNLLESVVYAISTAIGFALALIIFAGIREQLAMTHVP
                     EGMKGTPIALITAGLLAMAFMGFSGIV"
     CDS             8405..9445
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg437_10"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 6.8e-50, bitscore:
                     160.1, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKILVAGGTGYIGSHTTVELQNAGYEVVIIDDLSNSNIEVLDG
                     IEKITGIRPEFIQLDLKDKEGTRKALEAHPGIKGIILFAASKAVGESVQQPLKYYRNNI
                     VTLVNLLEMMPEFNIEGIVFSSSCTVYGQPDPQNLPVTENAPIKPAMSPYGNTKQINEE
                     IIRDTIHAGAPFKSIILRYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAMGIRKELSV
                     FGDDYDTADGSCIRDYINVVDLAKAHVIAMDRMLENKSDEHIEIFNLGTGNGVSVLELI
                     NTFEQTTGVKVPHKIVGRREGDIEKVWANPEHANKVLGWTAKETLADTLQSAWNWQKRL
                     RERGIQ"
     CDS             complement(9515..11896)
                     /locus_tag="ctg437_11"
                     /transl_table=11
                     /translation="MTNTTLNLEELLCGVNELVDTLWIVTLGNEKVEIIKDSMTPEREG
                     ECLDYTELCQTYIQEYVYPADLGKWEEILSLNSLRQMAASGVANKKFDMRFCNDLFGFE
                     WHEAFIRILKDKSGIPDRVILFSRYVNHCRKAQIVEAAVQTEYDYVVYIEANTNSYVMY
                     TSNRESGTPVPPIASNDYEKEVAEFHHKYVPEDQRDELTRNLSLDHVLSVLRNSREYVL
                     FCQVMENGVFRDKKLRFSFFDKERNILLLTRTDIMEVREEERQRQLLQDALQVAKSANQ
                     AKSDFLSRMSHDIRTPMNAIIGMTTIASMHIDDRERIVDCLKKIMVSSKLLLNLINEVL
                     DMSKVESGHILLTDEEFDMGELLQSVITMVQTSVSQKFQDFRVHLFQVKHEKLVGDVQR
                     IQQVLLNLLSNAIKYTPDYGKITLEIREKPIKNGNYGLFEVTVIDNGIGIKPDFLHKVF
                     EPFERAEDATLRNIQGTGLGMAISRNIAHMMNGEIQVESEYGKGSVFTFTMQLKLQDQG
                     CFEDDHLRDLPVLVVDDDIVCCENACMRINEIGMKGEYAISGEEAIGKVERAHHLNDDY
                     FAVILDLKMPGMDGIETATRIRKVVGRDIPIIILSAYDCPHFEEIAQRAGVDGFISKPL
                     MKSKLFYLMKSFAIKQEKKEEETEKPQYPFGNFEGKRILLVEDNSLNREIATVLLEETG
                     AVVEEAENGLVAVNMVKNSSPGYYDLVFMDIQMPVMNGYDSTRHIRALERPDIKSMPII
                     AMSANAFAEDIKLCKESGMNEHIAKPIDFGKVLEILEKYL"
     CDS             complement(11935..12567)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg437_12"
                     /sec_met_domain="HAD_2 (E-value: 4.8e-10, bitscore: 29.7,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKIKNIVFDLGGVIIDLDRDEPVRRLIEIGVKDADGLIDPYEQK
                     GVFQDLETGKIGVEEFCRYLRKYTGKDLSYEDICWAWFGFIGGVPQYKLDYILKLREKY
                     QVYLLSNTNPIIQLEWAQTKEFTPAGRPLNDYFDKLYLSYEIGVTKPDREIFDRMILDS
                     GIKPEETLFVDDGKNNIVVGQELGFHTYQPLNGEDWRGRLDEILSKS"
     CDS             complement(12690..13937)
                     /locus_tag="ctg437_13"
                     /transl_table=11
                     /translation="MAKIKPFKGVRPPKEFIEEVASRPYDVLNSQEARVEAEGNEKSLY
                     HIIKPEIDFPEGTDEHDPAVYLKAAANFNNFQEKGWLVQDQKECYYVYAQTMNGKTQYG
                     LVVGAYVPDYMNGTIKKHELTRRDKEEDRMKHVRVNNANIEPVFFAYPDNSELDAIVMK
                     YTAREPEYNFVAKLDGFGHTFWIIDEDKDIARITELFGEMPALYIADGHHRSAAAALVG
                     AEKAKQNPGHKGDEEYNYFMAVCFPANQLTIIDYNRVVKDLNGLTEEQFVERLTKNFVV
                     EEKGSAIYKPGALHNFSLYLGGKWYSLTAKPGTYDDNDPIGVLDVTISSNLILDEILGI
                     KDLRSDKRIDFVGGIRGLGELKRRVDSGEMKVALALYPVTMKQLMDIADTGNIMPPKTT
                     WFEPKLRSGLVIHKLD"
     CDS             complement(14010..14615)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg437_14"
                     /sec_met_domain="Hacid_dh_C (E-value: 8.9e-37, bitscore:
                     116.0, seeds: 144, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VAELVFGMLVYGVRNFYNGTSGTELKGKKLGILAYGNVGRNVARI
                     AKGFGMEVYAYDAFCPASVIEADGVRAVASTADLFKACQIVSLHIPATAETKGSINFEL
                     MNSMPKGAIVVNTARKEVMDEAGLAKMLEERPDFKYLTDIMPAIHAELAEKYAGRYFST
                     PKKMGAQTAEANINAGIAAAKQIVDFLVNGNEKYRVNK"
ORIGIN
        1 tcaactccgg agtcgggccg acttccatac cgaccttacg caagaccacc tcgtccatct
       61 tctggcgttg caataccaaa ggaacctcgt agatcgtcgg tacgtcgatc gactggatca
      121 cggaatcctc ggccacgtta cagaacaacg ccaccttacg taacaagttc gcgttcagct
      181 catgctccgt acgtaaaacc aacacgtccg gctggatgcc taactcctgc aattgcttca
      241 cggaatgttg cgtaggcttc gtcttatact ctttcgccgc cgcgatataa ggcacataag
      301 taagatgtac gcaaaggcag ttcttaccca gctcccattt caactggcga acgctctcta
      361 tgaaaggcag agactcgata tcacccaccg taccaccgat ctcggtgatc acgaagtcaa
      421 atttatactt gctacccaat aatttcacat tacgcttgat ctcatccgtg atatgaggta
      481 ccacctgcac cgtcttaccc agataatccc ccttacgctc cttgttgatc acgctttgat
      541 agatacgtcc ggtagtgata ttattcgcac gggtagtctg gacattcaag aaacgctcgt
      601 aatggcccaa gtccaagtca gcctcatgtc catcaacggt cacgtaacat tccccatgct
      661 cataagggtt caacgtaccc gggtcgatgt tgatgtaagg atcaaatttt tggatagtaa
      721 ccttgtaacc tcttgcttga aggagcttac ctaaagaagc ggaaataatt cccttaccta
      781 aggaagagac cacgccgcct gtaacgaaaa tgtactttgt atctgccacg atagtaatat
      841 tttagttatc tttttaattg cacacctgca tttcgaaacc gcaaagttag cgattttcat
      901 cgagacatgc caaatttaat gtttttattt ctcgctgaat atctccagaa ctgacccggg
      961 cttcggcagg actcttccga ttcccgaccc gaagcacggc actaaagaca gtacttctca
     1021 tggaattact tcggtactcc gcaggaagta ctgaagtact ttgaccgaag tattccagta
     1081 cttcctgcgg agtactgagg caagtccgta taagcctcgc tagacacacc tgctttgcct
     1141 cagtgatcgt aacttttacc cagataaata tcaaatcgta tgttgtatat cattcttttt
     1201 agctaatttt gcgaccacta caactaatag atgtaaataa ggtattatga tgatgaagag
     1261 gcatggtgtg tatgcgctat tattactttc actaattggg agctcggcat acagccaaga
     1321 gaaccaacta gttaccggaa cgatagttca acgtcccgca cagcaagtcg tatcggatga
     1381 tacgattcct gcgatcaatc ttggcgaaga ggaattagac aacatcgtag acattcgtaa
     1441 acaattcgag aaacaaaaca agacttactc ggcgcccttg gccccaagca cgaatttact
     1501 gcgtttcttg aaaaaagacg aactggagat ctcggacgag gcgatgtatt gggcccgtct
     1561 ggtacgagac gcctccacgg ctttcgataa tacgatgacc ttccgagaca ccgtgatcgt
     1621 aaacccttta ttcatgccga tcgttttccg gggagattat ctacccaaaa acttgatatt
     1681 ctataacttc gattcattga aggagaggac tccctatgat aacttatacc ggacagactc
     1741 catcttcaaa gatctggagc gaaacaaaca gttcgaggag atggcttaca aatatgtgca
     1801 gaacaattac ccgacttatt tccgctactc cgagagggat ctgcccaatg aggtgatcaa
     1861 acctaaattc atcaagaaga atatttatga ggacttgccg atcaaggtgg aggctgatgc
     1921 caattttgag gacgtagacg ctcccgctcg ctttatcccg gagcggagat actggatatc
     1981 ggccttcgag agcgccgtcc aattctccca gaactacgtt tcggagaact ggtacaaggg
     2041 tggaagtagc aacttgaacc tgttcaccaa gaacaattta aaatacgact ataagaaaga
     2101 taaggtacaa gtaacgaacg aactggaatt caaagccagc gtatatacgg caccgaagga
     2161 taccttaagg aactataaga tcggtgacga cgtattccgt atacacagca acgtcggcta
     2221 ccaagcgttc aacaaatggt actatacgtt cgacgctgag ttcaagaccc agttcttcac
     2281 caactaccaa gagaacgagc gcatcaaaca ggccgcattc ctagccccgt tctctatcaa
     2341 cttcggtctc ggtatgaaat acgagctgga aaaacaattt accgacaagc ataagaagat
     2401 taaattcagc accaacttgg cgccgatctc ctatacatat atgtatacga cacaagagat
     2461 cgattatagc cgtcacggtt tcaagaaaaa cgaggaaacc ggtgagttca ataacaagct
     2521 aagccaaata ggttccacga tccgcgcaga cctcgccttc gatttcaacc gtaacgtaag
     2581 ctggcaatcc cgtctttatt tctttaccac ttacggcgat cataccatcg gggagttcga
     2641 gaataccttg gttctggcca tcagccgctt tttctccaca cgtatctatt ttcaccttag
     2701 atacgacgat ggagtggaaa aaacagagga taacaagagt tatttccagc ttaatgagtt
     2761 gttaagtttc ggttttaatt acaaatggta agctaggatt taagatttcg aataataaac
     2821 tttgttaatc gtgacatagt ttctaaatta tacttacttt tgccttgatt ttgcaatgtc
     2881 gagattacaa atatgagcga aagtataaat catacaggat ttgtagagaa gatcgatggc
     2941 gacaccgtct tcgtccgtat tacccaacaa tccgcatgct cgggatgcca cgcacagtct
     3001 atgtgctcgg catccgagaa aaaggataag atcattgagg tacccgatcg gtcgggacgg
     3061 tttcacgtaa acgaggaagt gataatatgc ggacaaaatt ccatgggact tcaggccgta
     3121 ttgctagcat ttgtcattcc tttggtgata gtcgtggggg ccatcgtaat cgggacgaat
     3181 ctacaatggg acgagaccac gagcgggtta accggtttat cgcttttact gccttattac
     3241 tgtatactat acttaatgcg tgacaaacta aaaagacgat ttatatttac tttgaaaaaa
     3301 cttaattgat aatatatcat gattttaatt gccgttattt cattaggagc aatcggggcg
     3361 gtcggagcgg ttttcctcta cgctgcttcc aagaaatttg aagtctacga agatcctcgc
     3421 atcgcgcaag tacaggaagt ccttcccggg gcgaactgtg gaggttgcgg ttatccgggt
     3481 tgcgccggat tcgcaggcgc ttgcgtaaaa gctgactcat tagacggatt gctctgcccc
     3541 gttggtggtg gcccggtcat ggccaaggtc gctacaatac tgggtaaaga ggcgggtaca
     3601 gccgaaccca tggtagccgt tgtccgttgc aacggaactt gtcaggcccg cccacgtaca
     3661 aactcttatg atggaacgaa aagttgcgcc atcgcctcta ccctttacgg aggcgagacg
     3721 aattgttctt tcggttgcct aggttatggc gactgcgtga acgcctgcgc tttcgatgcg
     3781 atccacatca acccggctac gggaatcgcc gaggtggacg aggaaaaatg tacttcctgt
     3841 ggtgcttgtg tgaaggcttg cccgaagaat atcatcgagc taagaaagaa aggacctaaa
     3901 tcacgccgga tttacgtgtc ttgcgtaaat aaggacaagg gagccaccgc tcgcaaggct
     3961 tgtgccaacg cttgtatcgg ctgtggcaaa tgtgccaagg aatgtccgtt cgaggcgatc
     4021 accgtaacaa ataacgtagc ttatatcgat tatacgaagt gccggatgtg ccgcaaatgc
     4081 gtggctgtat gtccgacagg ggctattcat gagctgaatt tccctcctcg caaggaagcc
     4141 gctcccgctc cgaaagcgga gaccgtgaaa ccggcaccga aggcagaggc taccgtgaaa
     4201 ccggaagccg ctccgaaagc tacaagtgaa gaaaaaacaa atctaaatta aaatctaata
     4261 gtatgctaag gacatttcga atcggaggta tacatccccc cgagaataaa ctgtctgccg
     4321 gtaagaaaat tacggctctc gctacgccta aacaggtgat tatccccctc agccagcata
     4381 tcggcgcccc ggcgcaggcc gtggtgaaga aaggggatct ggtaaaggtg ggtacattgc
     4441 tagccaaggc gggtggtttc gtatcagcga acatccactc ttccgtatcc ggcaaagtga
     4501 acaagataga taacgctctc gacgctagcg gatacaaacg tcccgctatc tatatagatg
     4561 tggaaggtga tgaatgggaa gagacgatcg accgcagcga ggccttagtg aaggaatgct
     4621 cgctgtcttc caaggaaatc gtggataaga tcgccgcttc cggtatcgtc ggtctgggtg
     4681 gagcgacttt ccctacgcag gtgaaattga tgccgcctcc cggaaacaag gcagagatcg
     4741 taatcatcaa cgccgtggag tgtgagcctt atcttacttc cgatcattcg ttgatgctgg
     4801 agaaaggcga gcaaatccta gtcggtgtca cgatcctaat gaaagcggtc aacgtgaaca
     4861 aggccgtgat cggtatcgag aataacaagc cggacgctat cgcccatctg caaaagttgg
     4921 cggtaaatta taaaggtata gagatcatgc cgcttaaggt acaatatccg caaggaggcg
     4981 agaaacaatt gatcgacgcc gttattcgcc gtcaggtaaa aagtggtgcg cttcctatct
     5041 cggcgggtgc cgtggtacag aacgtaggaa ccgcttatgc cgtttacgag gcggtacaaa
     5101 agaataaacc gttgttcgag cgtgtggtga cgatcacggg taaggcggta gctaatcctt
     5161 ccaatttctt ggttcgtatg ggaacaccga tcagttgctt gatcgaggcc gcaggtggcc
     5221 tgcccgagaa tacgggtaag attatcggtg gcggaccgat gatgggtaaa gcgttgatca
     5281 gcgccgaggt gccggtttgc aaaggaagct ccggtgtttt attactgacg acggaggaat
     5341 ctgtccgcaa gccgatccgg gattgcatcc gttgcgccaa atgcgtaggt gtctgcccga
     5401 tgggattaaa ccctacccta ttgatgaacg ccacggaatt ccagaattgg gaattggcgg
     5461 agaagaacta tatcaccgac tgtatcgagt gcgggtcgtg tagttatacc tgtccggcca
     5521 accgtccgtt gctggatcag atccggtttg gtaaaggaaa agttatgggt attatccggt
     5581 ctagaaagtc ataaaacaag agcaacatgg aaaataattt atacgtatcg ccctcgcccc
     5641 acatccatgg tggcgacagc ataagcaaaa atatgtatgg tgtactgatt gcccttatcc
     5701 cggctttctt ggtatccctt tatttcttcg gtctgggagc gttgatcgtt acggtcgtat
     5761 cggttctggc ctgtatgata ttcgagtatt tgatccagcg attcctgatg aaaaaggaac
     5821 cgaccctttg cgatggctcc gctatcctga cgggtgtatt gctggccttc aacctacctt
     5881 ccaaccttcc ggtctggatc attattatcg gagcgttagc ggcgatcggc attggcaaga
     5941 tgtctttcgg tggattaggt aataatattt tcaatccggc gttagtcgga cgtgtattct
     6001 tattgatctc cttcccggca cagatgacga cttggccggt ggtagatgcc ttgaacgttt
     6061 tcccgatgac ttatacggat gcccagaccg gcgcaacggt attgtcgttg atgaacgaag
     6121 gcgtgaccga gcttccgtct tacgggaaca tgcttgtagg agctatggga ggtagtctcg
     6181 gtgaagtgag cgccgtggcc ttgatcctcg gtcttttatt catgctatgg aaaaagatca
     6241 tcacttggca gatcccggta tccatcttgg ctaccgtatt cgtattcacg ggtatcatgc
     6301 acttggtgaa tccggtacaa tacgccagcc cgttcgttca cttattatcc ggcggtttgt
     6361 tattaggctc catctttatg gcgaccgact acgtaacctc gccgatgagc aagaacggaa
     6421 tgcttgtcta cggcgtggga atcggaatcc ttaccacggt gatccgtttg ttcgggtctt
     6481 acccggaagg tatgtcgttc gctatcctga tcatgaacgc atttactccg ctaatcaaca
     6541 gctatatcaa acctaaacat ttcggaggaa agtaagcatg gcaaaattaa aatcaacatt
     6601 acccaatatg ctcctttcac taacaggcat ttgcttggta gcaggggcga tcctagccgg
     6661 agtgaaccag tttaccgccg gccctatagc ggtagctaaa gcgaccgcct tggaggaagc
     6721 gattaaagcc gttgctcccg agttcgacaa caaaccgact gaggacgtct atatggccgt
     6781 ctcctccgat ggtgattccc tcaagattta tcctgccaag aaaggcggac aagtcgttgg
     6841 cggagccgta gagagtaata cgaaaaaagg ctttagcggt gagatacggg ttatcgtagg
     6901 tttcgatatg gatggcaaga tcttgaacta ttccgtattg caacacgccg agactccggg
     6961 tttgggagcc aagatgcaag aatggttccg tgcggacaag aacaagcaaa gtgtcttggg
     7021 acgtacgatt ccggacggag gcttaaaagt aacaaaagat ggtggcgacg tggacgctat
     7081 cacggcagcg accatctcca gccgtgcgtt cctcgatgcc gtgaaccgtg cgtatagcgc
     7141 attcgcaggc gtagacggat taacgggtgc cacttcaact gataacaaat aaaaagggag
     7201 gacagaacaa tgagtaatct aaaaatattg atgaatggta tcatcacgga gaacccgaca
     7261 tttgtattac tgttaggtat gtgtccgacc ttgggaacga cctcttcggc catcaacggc
     7321 atgagtatgg gattggctac gatgttcgta ttgatttgct cgaatatcgt gatctccgcc
     7381 ttgaaaaacg taatccccga cttggtgcgt atcccgggat atatcgttgt gatcgcgacg
     7441 ttcgtgaccg tagtgcagat gtgcatggaa gcgttcgtcc cggctttata cgctagctta
     7501 ggattattta tcccgttgat cgtggtaaac tgtatcgtac taggacgtgc cgaggctttc
     7561 gccgcgaaga acggaattat cccgtcggcc cttgatggta tcggaatggg acttggtttc
     7621 acgatggctc ttacgctgct gggcgcttgc cgtgagttct tgggaaccgg taagttattc
     7681 aacgtaacct tgatgcccga ggaatacggt tcgctgatct tcgtattggc tccgggagcg
     7741 tttatcgcct tgggttatct ggtagcaata gtaaacaaac tgcgtaaagc ataataaacg
     7801 gatcatatgg aatatatatt gatatttatc gccgccgtat tcgttaataa cgttgtactg
     7861 gcacagttct tgggaatttg tccgttcttg ggggtatcta agaaagtgga gactgccgca
     7921 ggcatgggag ccgccgttac gttcgtgctt acgatcgcca cgattgttac attcctcgtg
     7981 caaaaataca tattggacgc tttcggatta gggttcatgc agacgatcag tttcatcttg
     8041 atcatcgccg ccttggttca gatggtggaa atcatattga agaaggtctc tcccgccctt
     8101 tatcaagcgt tgggtgtatt ccttccgttg atcaccacga actgctgtat cttgggtgtg
     8161 gctatccttg taatccaaaa agagtataat ttattagaat ctgtggtata tgctatctcg
     8221 accgctattg gatttgcgct agctttgatt atcttcgcgg gtattcggga gcaactagcc
     8281 atgacgcatg ttccggaagg catgaaaggc actcctatcg ccttgataac ggccggtttg
     8341 ctagctatgg cttttatggg attctcgggt atcgtataac aaacttatct aaatgaacac
     8401 tagaatgaaa aagaagattt tagtagcggg cggaaccggt tatatcggct cacacaccac
     8461 agtagaattg cagaacgccg gatatgaggt agtcattatc gacgatttgt caaactcgaa
     8521 tatcgaggtg ctcgatggta tcgagaaaat cacgggcatc cgtccggagt ttatccaatt
     8581 ggatctaaag gataaggaag gtactcgcaa ggcattggaa gctcatccgg gcatcaaagg
     8641 cattatcttg ttcgccgcta gcaaggcggt aggagaatcc gtacagcagc ctttgaagta
     8701 ttatcgcaat aatattgtca ctttggtgaa cttgttggag atgatgcctg aattcaatat
     8761 cgaaggtatc gtattctctt cctcttgtac ggtatacgga caaccggatc cgcagaactt
     8821 gccggtaacc gagaatgccc cgatcaaacc cgctatgtct ccttatggaa acacgaagca
     8881 gatcaacgag gagattatcc gggatacgat ccacgcggga gcgcctttca agagtatcat
     8941 cttgcgctac ttcaacccga taggcgctca cccaagcgca gagatcggcg agttgccgaa
     9001 tggtgttccc cagaacttga tcccgtactt gacacaaacg gctatgggta tccgcaagga
     9061 attaagcgta ttcggcgatg attatgatac agcagacggt tcttgcatcc gtgactatat
     9121 caatgtcgta gacttggcga aagcacatgt aatcgctatg gaccgtatgc ttgagaataa
     9181 gtctgatgag catatcgaga tattcaacct aggtaccggc aatggtgttt ctgtccttga
     9241 actgatcaat accttcgagc agacaacagg cgttaaggtt ccgcacaaga tcgtgggccg
     9301 tcgtgaaggt gatatcgaga aggtatgggc caatccggag cacgcgaata aggtattagg
     9361 ctggaccgcc aaggagactt tagccgacac cctgcaatcc gcatggaact ggcagaaacg
     9421 tttgagagaa cgtggcatcc agtaaataac acaaaaaaag aggccgtatc tgatagcgct
     9481 tagctaagat acggcctttt ttatatcctt atatctacaa gtacttctct aagatctcaa
     9541 gaaccttccc gaaatcgatc ggcttagcga tatgctcatt cattccggat tctttacaca
     9601 acttgatgtc ttccgcaaat gcgttcgcag acatggctat tatcggcatg gacttgatat
     9661 ccggacgttc taatgcccga atatggcgag tagagtcgta cccgttcatg accggcatct
     9721 ggatatccat aaataccaag tcataatatc ccggactaga gttttttacc atattcaccg
     9781 cgacaaggcc attttccgcc tcctctacca ccgcaccggt ctcttctagc aacacagtcg
     9841 ctatttccct attcaagcta ttatcttcca ccagcaagat ccgcttaccc tcaaagttac
     9901 cgaaaggata ttgaggcttc tccgtctctt cctctttttt ctcttgcttg atagcgaaac
     9961 ttttcatcaa ataaaataac ttggatttca tcaacggctt acttatgaat ccatcgacac
    10021 cggctcgttg ggctatctcc tcaaaatgcg gacaatcata agcagaaaga ataatgattg
    10081 gaatatcccg gccaacgact tttcggatac gggtagcggt ctcgatccca tccattcccg
    10141 gcattttcag atcaaggata acggcaaaat agtcatcatt aagatgatgt gccctctcta
    10201 ctttcccgat agcctcctca ccagaaatgg catactcgcc tttcataccg atctcgttaa
    10261 tcctcataca tgcgttctcg caacacacga tatcatcgtc taccacgaga accggtaaat
    10321 cccttaaatg atcatcctca aaacaccctt gatcctgcaa tttcaactgc atcgtaaatg
    10381 taaaaacgga acctttgcca tattcactct ccacctgaat ctcaccattc atcatatgag
    10441 cgatattacg gcttattgcc atgcctaagc cggttccttg tatattccgc agggttgcgt
    10501 cttccgcacg ttcaaatggc tcgaaaacct tgtgtaagaa atccggcttt atcccgatac
    10561 cattgtctat aaccgtaacc tcaaataaac cataattacc atttttaatt ggcttttccc
    10621 gtatctcaag tgttattttc ccatagtccg gcgtatactt tatggcgttc gacagcaaat
    10681 tcaacaatac ttgctgaatc cgttgcacat cgccaaccag cttttcatgt ttgacttgaa
    10741 acaagtgaac ccggaaatcc tgaaacttct gactgaccga agtctgaacc atagtaatta
    10801 cgctttgcaa taactcgccc atatcgaact cctcgtctgt cagcaaaata tgtccgctct
    10861 ctaccttaga catatccaag acctcattga tcaagttcaa taataatttg gaagaaacca
    10921 taatcttctt caagcaatcc actatacgct ctcgatcgtc gatatgcata ctggcgatag
    10981 tggtcatacc gataatggca ttcatcggag tacgtatatc atggctcata cgggataaga
    11041 aatccgattt agcctgattt gccgatttag ccacttgtag ggcatcttga agtaattgcc
    11101 tttgccgctc ttcctcacga acctccataa tatcggtccg ggtcaaaaga agtatattcc
    11161 tctccttatc gaaaaagcta aaacgcaact tcttatccct aaaaacgcca ttctccatca
    11221 cctgacagaa caagacatac tcacgggaat ttcgtaagac agataagaca tgatctaggg
    11281 aaagatttcg ggttaactca tctcgctgat cctccggcac atatttgtgg tggaactcgg
    11341 ctacctcttt ttcatagtca ttactcgcta tcggggggac cggcgtccca ctttcacgat
    11401 tggaagtata catgacatag ctattcgtgt ttgcctctat ataaacgaca taatcatact
    11461 cagtctgaac ggcagcctct acgatctgtg ccttgcgaca atgattcaca tagcggctga
    11521 aaagaatgac acgatccgga attccactct tatctttcaa gatacgaata aaagcctcat
    11581 gccactcaaa accaaacaaa tcattacaga aacgcatgtc gaacttctta ttcgctacgc
    11641 cgctagccgc catttgccgc aatgaattca aggataagat ctcctcccat ttccctaaat
    11701 ccgcaggata tacatattct tgaatgtaag tctggcaaag ttctgtataa tccaaacatt
    11761 ctccttccct ttcgggagtc atcgaatctt tgattatctc aaccttttca ttacctaatg
    11821 tgacgatcca aagcgtatcg actagctcgt ttacaccaca gagtagttct tccaaattta
    11881 aagtagtatt tgtcattttc aatgatatag atttaattaa gaggaataga gatcctatga
    11941 ttttgagagt atttcatcga gcctccctct ccaatcctct ccattcaaag gctgataggt
    12001 atggaaccct agttcctgcc ccactacgat attattctta ccatcatcta caaataatgt
    12061 ttcctctggt ttgattcctg aatccaagat catgcgatca aaaatttcac gatccggctt
    12121 cgtgacaccg atctcataag agagatacaa tttatcgaaa taatcattta atggacggcc
    12181 cgccggcgta aactcttttg tctgtgccca ttcaagctgt atgatcggat ttgtattgct
    12241 caataaatag acttgatatt tctcacggag ttttaatatg tagtccaatt tatattgggg
    12301 aacgccgcca atgaagccaa accaagccca acaaatatcc tcataagaaa ggtctttacc
    12361 cgtatacttc cgtaaatagc gacaaaactc ctctactccg atctttccgg tctccagatc
    12421 ttgaaaaacc cctttttgtt cgtaaggatc tatcaatcca tcggcatctt tgaccccaat
    12481 ctctattaaa cggcgaacag gttcatcccg gtccaaatct atgataacgc cccccagatc
    12541 gaatactata ttttttattt tacccattgc gatactattt aagtcccaaa gatacaattt
    12601 attccgtata tctaggttac aaggataaaa aagggtataa tcttcaacga ttatacccca
    12661 atccaaagct atatttatgt atataagact taatccaatt tatggatcac caaaccggag
    12721 cgaagcttcg gttcgaacca cgtcgtcttc ggcggcatga tattacccgt atcggcgata
    12781 tccatcaatt gcttcatcgt aacgggatac aaagccaagg caaccttcat ctcaccgcta
    12841 tccacacggc gtttcaattc acccaggcca cggatacctc ccacgaaatc gattcgcttg
    12901 tccgaacgta aatccttaat gcctaaaatc tcatccagaa tcaagttcga agagatcgtg
    12961 acatccaata cgcctatcgg gtcattatca tcgtacgtac cgggcttagc ggtcaaagaa
    13021 taccatttcc ctcctaaata cagggagaaa ttgtgcaagg cacccggttt gtaaatagca
    13081 gaacccttct cctctaccac gaagtttttc gttaatctct caacgaattg ttcctcggtc
    13141 aagccgttca agtcttttac cacacggttg taatcgataa tggtcaattg gttggccggg
    13201 aagcaaacag ccatgaaata gttatactcc tcgtctccct tatgacccgg gttttgcttg
    13261 gccttctccg ctcctaccaa agcagcggcg gcggaacgat gatgtccgtc ggcaatatac
    13321 aacgcaggca tctccccgaa taactccgtg atgcgagcga tatccttatc ctcatcgata
    13381 atccagaacg tatgtccgaa accgtctaat ttcgccacga aattatattc gggctcacga
    13441 gccgtatatt tcataacgat agcgtctagc tctgagttgt cgggataagc gaagaatacc
    13501 ggctcgatat tagcgttgtt gacacgtacg tgtttcatgc gatcctcctc cttgtcacgg
    13561 cgggtcagct catgtttctt gatcgtgcca ttcatataat cgggaacata agccccgact
    13621 accaacccat attgagtctt gccattcatg gtttgggcat aaacataata gcattctttc
    13681 tgatcctgaa ccaaccaacc tttttcctga aaattattga aattggcggc ggccttcagg
    13741 taaacagccg gatcatgctc atccgtccct tctgggaaat cgatttccgg tttaatgata
    13801 tggtaaaggg atttctcgtt tccttccgct tccacacgag cttcttgcga gttcaatacg
    13861 tcatagggac gggaagccac ctcctctata aattcttttg gcggacgaac tcccttgaaa
    13921 ggttttattt ttgccatggt aattaaatct aattggttta tgtatcaatg tagagacggg
    13981 gcgtgccccg tctctacaac cggatattct tatttattaa cccgatactt ttcattgcca
    14041 ttcaccaaga aatcaacgat ctgcttggcg gcggcgatac cagcgttgat attagcctcg
    14101 gcggtctggg cacccatctt tttcggggtg ctgaaataac gaccggcata tttctcggcc
    14161 aattccgcat ggatagcggg cataatatct gtcaagtact tgaagtccgg acgctcttcc
    14221 aacatcttag cgagtccagc ctcatccatc acctccttac gagccgtatt cactacgata
    14281 gctcccttcg gcatggaatt catcaactcg aaattgatag aacccttcgt ctcggccgta
    14341 gccggaatat gcaaagagac gatttggcaa gccttaaaca aatcggctgt agaagctaca
    14401 gccctcacac catcggcctc aatcacggaa gccggacaga acgcatcgta agcgtaaacc
    14461 tccataccga agcctttagc gatacgagcc acgttacggc ccacgtttcc ataagccaag
    14521 atacccaatt tctttccttt caactctgtt ccggaagtac cgttatagaa attacgaacc
    14581 ccatacacca acataccgaa taccaattcg gcgaca
//
