LOCUS       c00432_gnlPro..        13289 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AAMOAOPP_432.
ACCESSION   c00432_gnlPro..
VERSION     c00432_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 13:06:57
            Original ID  :: gnl|Prokka|AAMOAOPP_432
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 7920
            Orig. end    :: 21209
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13289
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[17920:21209]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13289
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..13289
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13289
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(152..550)
                     /locus_tag="ctg432_6"
                     /transl_table=11
                     /translation="MFHTVLGTPDNKIIYIPNGSLSSGVVTNFSNQTTRRVDWTFGVEY
                     GSDYEKVKQVIESVLAKDSRILSEPAAPFIALTALADSSVNVVVRVWVNSSDYWGVYFD
                     INKNIYATFNEVGIGFPFPQLTVHQAKD"
     CDS             551..748
                     /locus_tag="ctg432_7"
                     /transl_table=11
                     /translation="LYFFYRATNTLRLDIITHLIRLEKKDDQSTGKVRQVTAQCHTDSD
                     TGGSQQSSKRRSLNSQRSYD"
     CDS             762..1013
                     /locus_tag="ctg432_8"
                     /transl_table=11
                     /translation="MVKLTFTKLPTKVLTEGSISRLLNIFRTSLFSKFITNRPTKKTIR
                     ALIIVKPNWEPCSTKDLIASSNLELASTAANNTISLLF"
     CDS             1156..1977
                     /locus_tag="ctg432_9"
                     /transl_table=11
                     /translation="MKILAILAALFLSIGYGHAQTYEKFVEKSFDFLDKNDLVSAEESL
                     RAAMRLEPGNPNNYALLMNLGTIQRRQGKLEDALLSYTAALSRHPNNEAILENRAGLYT
                     EMGEIEKATNDYNALLILNPHHQEALYCRAMLHLQHKNYLLAEQDFDKILEVNEKSVKG
                     RLGHAILEKLRGNYDESERIFNYLISEMPREWILYEGRADLYFMMGKNARAMADINRVF
                     VESTPTAALYVLRGKVKLAQYEKASAALDFKKAEDMGYDKTTIDELMKMAR"
     CDS             complement(2110..2886)
                     /locus_tag="ctg432_10"
                     /transl_table=11
                     /translation="MRKKLGLFANIRPVQTFKCLLHKSPLRAELVDGADFLCIRELTGG
                     MYFGEKYQDNDKAYDTNMYTRPEIERILKVGFEYAMKRNKHLTVVDKANVLASSRLWRQ
                     IAQEMAPRYPEVTTDYMYVDNAAMRMIQEPKFFDVMVTENTFGDILTDEGSCISGSMGL
                     LPSASTGESTPVFEPIHGSWPQAKGLNIANPLAQILSVAMLFEYFDLKEEGALIREAVD
                     ASLDANVRTPEIQVEGEAKYGTKEVGSWIVNYITEK"
     CDS             2899..3654
                     /locus_tag="ctg432_11"
                     /transl_table=11
                     /translation="LLRAYFRCRIIIKLRIAHGREKNSVGILTNPIGLLRERIAYLIDR
                     VSATKGILIVNLMSKFLTNGTHYFHALHGNLWSDPVSGKYCYIQFHRKCLLLFSVKMYI
                     LRLRGKIRVIVPQGTCNHQVGAITVTSDRYVMNTALAKQHLDVGLVRLRIQVVYQKDRQ
                     IDLLTDNHSGNLSIASHRTGMHASNIRVHPFFLESFTNQTSGGTRTNNMVVRQELCVMY
                     RPFYHFRLTIVVRYKRDSQLFHTLYLFNY"
     CDS             complement(3651..5153)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg432_12"
                     /sec_met_domain="HMGL-like (E-value: 1.5e-48, bitscore:
                     156.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTTLRDGEQTSGVSFAAHEKLSIAQVLLSDLGVNRVEIASARVS
                     DGEFEAVKRVAAWAARSGNLDKLEVLGFVDGTVSLDWIESAGCRVVNLLCKGSYKHVTE
                     QLRKTPEQHVDDIRTVVLEAAKRKIDVNIYLEDWSNGIKHSPNYVFLVIDALKGLPIRR
                     FMLPDTLGVLNPGNTYEYCKMMVDRYPDLRFDFHAHNDYDLAVANVYSAIRAGIKGIHT
                     TVNGLGERAGNAPLSSVLAVIKDQLGEETNLREEKINKASRLVETYSGVHIPPNKPIIG
                     EHVFTQCAGVHADGDSKNNLYCNDLLPERFGRVREYALGKTSGKANIRKNLEALGIDMD
                     EGSMRKVTERIIELGDKKEMVTPEDLPYIISDVLHHDNALEDQKIRILNYSLSLAQGLK
                     PVATLKIEINGEAYEESASGDGQYDAFVRALRRIYSRLNRPFPMLTNYSVSIPPGGRTD
                     AFVQTVISWNYAGVDFKTRGLDADQTEAAIKATLKMLNKIED"
     CDS             complement(5168..5755)
                     /locus_tag="ctg432_13"
                     /transl_table=11
                     /translation="MKTKFNIITSTCVPLPLENVDTDQIIPARFLKATTKEGFGENLFR
                     DWRYDKEGNKIESFVLNDPTYSGKILVAGKNFGSGSSREHAAWAIADYGFRVVVSSFFA
                     DIHKNNELNNFVLPVVVTEEFLAELFDSIYKNPKTEVEVNLPEQTITNKATGKSEHFEI
                     NAYKKDCLINGLDDIDYLLANKSKIEAFEAAR"
     CDS             complement(5782..7179)
                     /locus_tag="ctg432_14"
                     /transl_table=11
                     /translation="MSKTLFEKIWDKHVVDTLPDGTIQLYIDRLYCHEVTSPQAFAGLR
                     ARGLKPFRPAQITCMPDHNIPTLNQDKPIEDPISKNQVDTLEENAKYFGLTYYGLQHPK
                     NGIIHVVGPETGLTQPGMTIVCGDSHTSTHGAMGAIAFGIGTSEVEMTLATQCIMQRKP
                     KTMRITIDGVRKPGVTAKDFALYIISKMSTSGATGYFVEYAGKAIRNTTMEERLTICNL
                     SIEMGARGGMIAPDDVTFDYLKDREFAPRGEEWERKVSEWRQLYSDPDAKFDKEIVFHA
                     EDIDPMVTYGTNPGMGMSISKNIPSLESVPEAGRISYKKSLDYMGFKAGESMLGKKVDY
                     VFLGSCTNGRIEDFRAFASLVKGKKKADDVTVWLVPGSWQVEREIRAEGIDKVLAEAGF
                     VLRQPGCSACLAMNEDKVPAGKYAVSTSNRNFEGRQGPGARTILAGPLVAAAAAVTGKI
                     TDPRELM"
     CDS             complement(7194..8696)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg432_15"
                     /sec_met_domain="HMGL-like (E-value: 9.2e-95, bitscore:
                     307.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRLFIFDTTLRDGEQVPGCQLNTVEKIQVAKALEQLGVDVIEA
                     GFPVSSPGDFKSVVEISKAVTWPTICALTRAVEKDIDVAAEALKFAKRGRIHTGIGTSD
                     SHIKYKFNSTREEIIERAIAATKYAKKYVEDVEFYCEDAGRTDNEYLARVVEAVIKAGA
                     TVVNIPDTTGYCLPDEYGAKIKYLMEHVDGVHNAILSTHCHNDLGMATANTVQGVLNGA
                     RQVEVTINGIGERAGNTSLEEVAMVFKSHKERDIITNITTNKIYSTSRMVSSLMNMPVQ
                     PNKAIVGRNAFAHSSGIHQDGVLKNAQTYEIIDPKDVGIDDNAIVLTARSGRAALKHRL
                     HVLGVDLEQEKLDKVYDEFLKLADRKKDINDDDVLMLVGKDRTATHRIKLEYLQVTSGV
                     GVQSVASICLNLSGVRRYEAAAGNGPVDAGIKAVKKAISNSDMTIQEFLIQAINKGSDD
                     TGKVHMQVEYNGATYYGFSANTDIIAASVEAFVDAINKFIVD"
     CDS             complement(8859..9077)
                     /locus_tag="ctg432_16"
                     /transl_table=11
                     /translation="MMGNVSSLYCPSLRPNDGQCYLVTDTIVYLTFYKKYTVKNFELYL
                     VVSKKAVSLQRSNKNNKNKNNDTQLAK"
     CDS             complement(10001..11035)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg432_17"
                     /sec_met_domain="IlvN (E-value: 1.3e-47, bitscore: 151.8,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4.1e-40, bitscore: 127.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQSLN
                     LRDNGFNVIVGQRQGKTYEKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMSVWP
                     KMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRSMFLEGRGLN
                     SSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGLLLA
                     QYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMGPFH
                     DAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRESEMWQTAVTVRKLR
                     PENN"
     CDS             complement(11094..11819)
                     /locus_tag="ctg432_18"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFDLADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             complement(11826..12380)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg432_19"
                     /sec_met_domain="ALS_ss_C (E-value: 2.4e-17, bitscore:
                     53.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             complement(12396..13289)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg432_20"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.4e-51, bitscore:
                     163.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="TNECDVLIAIGMRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNV
                     AVDVKVLGNAKHTIPMITALLEERKRPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMG
                     EVVRKVSEATGNDAVLVTDVGQNQMMGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAK
                     FGAPDRTVCFFTGDGGMQMTIQELGTIMQEKLNVKIIILNNNFLGMVRQWQELFFHERY
                     SNTIMENPDFVAIAKAYGIAGRAVEKREELDDAIAEMLNHDGAYVLVANVETCGMVYPM
                     VPAGGSVTNMILGDEK"
ORIGIN
        1 tatacactct gtgtctaatc tctaatttgc gattcacaaa gataaatctt tttgttcaac
       61 catctataaa ataatcgcac atctaacgaa acttaaagat ttttgaacaa agagattcct
      121 tttaaggaca agtcatagat tatcacgaac ttcaatcctt cgcttggtgt acggtaagtt
      181 gcgggaatgg gaaaccgata cctacctcat tgaaggtcgc gtagatattc ttgttaatat
      241 cgaaatacac gccccaatag tcggaactgt ttacccaaac acgtaccacc acgtttacgc
      301 tgctgtccgc caaggctgtc aaggcgataa acggagcggc cggctcggac aagatgcggg
      361 aatccttcgc taatacagac tctatcactt gctttacttt ctcataatcg cttccgtatt
      421 ccacgccaaa ggtccagtct acacggcgag tcgtctggtt actgaaatta gtcacaacgc
      481 cactactcaa ggagccgttc ggtatataga taatcttatt gtccggagta cccaataccg
      541 tatgaaacat ttgtatttct tttaccgtgc caccaacacc ttgcgcctcg atataatcac
      601 ccaccttata aggcttgaaa agaaggatga tcaatccacc ggcaaagttc gacaggttac
      661 cgctcaatgc cataccgaca gcgacaccgg cggaagccaa caaagcagca aacgacgtag
      721 tctgaactcc caacgctcct acgactgaaa taatcaatag aatggttaaa ctgacattca
      781 ccaaactgcc gacaaaagtc ttgacagaag gatcgatatc ccgtttgctc aatatcttcc
      841 gaaccagttt atttagtaag tttataacca atcgtcccac caaaaagaca ataagggctt
      901 taataatcgt aaaacccaat tgggagccat gctcaaccaa ggatctgata gcttcctcta
      961 atttagaact cgcttctaca gctgctaata ataccatatc tcttctattt tagttaatct
     1021 attaattata taacaatctg atcttccaaa aatattatga aatgtagcaa aggtataaag
     1081 tttttttaat ctggtaaaac catgaaataa ttacgtagct ttgcatcaat caaataacac
     1141 gttaaatacg acagcatgaa aatccttgcg atactcgccg cccttttcct ttcaataggc
     1201 tatggccacg ctcagacata cgagaagttt gtcgagaaaa gttttgactt cttggacaag
     1261 aacgacttag tctccgccga agagagccta cgagccgcca tgcgccttga accgggcaac
     1321 cccaataact atgccttgct catgaacctc gggacgatac agcgcaggca agggaaactg
     1381 gaagatgccc ttctctccta taccgccgcc ctaagccgcc atccgaataa tgaggctata
     1441 ttggaaaatc gtgccggctt atatacggaa atgggtgaga tcgaaaaagc gacgaacgat
     1501 tacaatgccc tgttaatctt gaacccccat catcaagagg cgttatattg cagggcaatg
     1561 cttcatttgc aacataagaa ctatcttttg gccgagcagg atttcgataa gatactggaa
     1621 gtaaacgaga aatccgtgaa aggacgtctg ggacacgcga ttctcgaaaa gctacggggg
     1681 aattacgatg agagcgaacg catctttaat tacttgataa gcgagatgcc ccgtgaatgg
     1741 atcttatacg agggccgtgc cgatctatat tttatgatgg gcaagaacgc ccgggctatg
     1801 gccgatatca atcgtgtttt cgtggaaagt accccgacag ccgctttata tgtattgcga
     1861 ggcaaagtaa aactcgccca atatgagaag gcatcggccg ccttagactt caagaaagct
     1921 gaggatatgg gatatgataa aacgactatc gacgagttga tgaagatggc tcgttaaggt
     1981 tgtttttata cgtatagtgg catcggctca cgcgagtagt ggcgtaggcc aataccacta
     2041 ctcgcgtgag ccgatgccac tatacgtgtg agcctgcgcc actactggtg cgaaatcggc
     2101 ccatttatac tacttttccg tgatataatt gacaatccaa ctacccactt ctttcgttcc
     2161 atatttcgct tcgccttcca cttggatttc cggcgtacgg acattcgcat caagggaagc
     2221 gtctacagct tcacggatca aggcgccctc ttctttgagg tcgaaatact cgaataacat
     2281 cgctaccgaa aggatttgcg ccaaggggtt cgctatattc agccctttcg cctgcggcca
     2341 agagccatgg atcggctcga aaaccggtgt gctctctccg gtagaagcgg aaggcagcaa
     2401 gcccatagag ccgctgatgc aagaaccctc atccgtcaag atatcaccaa atgtattctc
     2461 ggttaccatc acgtcgaaga atttcggctc ttgaatcata cgcatagcgg cgttgtccac
     2521 atacatatag tctgtcgtta cttccggata gcgaggagcc atctcttgag cgatctgacg
     2581 ccacaaacgg gaagaagcaa gtacgttcgc tttgtcaacg acggtcaggt gcttattccg
     2641 tttcatcgca tactcgaagc ccactttcaa gatacgctcg atttccgggc gggtatacat
     2701 attcgtatcg tatgccttat cgttgtcttg atatttctcg ccgaaataca taccaccggt
     2761 caactcacgg atacacaaga aatccgcgcc atccaccaat tcggcacgca acggcgattt
     2821 atgcaacagg catttgaagg tctgcaccgg acggatatta gcgaacaggc ccaacttctt
     2881 acgcatcgct aaaagacctt gctccgggcg tactttcgct gtcggatcat tatcaaactt
     2941 aggatcgccc acggccgaga aaagaacagc gtcggcatcc ttacaaatcc gataggtctc
     3001 ctccgggaaa ggatcgccta ccttatcgat cgcgtcagcg ccacaaaggg catactcata
     3061 gtgaacctca tgtccaaatt tctcacaaac ggcactcatt acttccacgc cttgcacgga
     3121 aatctctggt ccgatcccgt ctccgggaag tactgctata ttcagtttca tcgtaaatgt
     3181 ttgttattat tctctgttaa aatgtacata cttaggctcc gtgggaaaat acgtgtcatc
     3241 gtcccacagg gtacttgtaa tcatcaagtc ggcgctataa cggttacaag cgataggtac
     3301 gttatgaaca cggcactggc gaagcaacat ctggatgtcg gcctcgtgcg gttgcgcatt
     3361 caagtcgtct atcaaaaaga ccgccaaatc gatctcctta cggacaacca tagcggcaat
     3421 ctcagcatcg cctcccatcg gaccggaatg catgcaagca atatccgcgt tcaccccttt
     3481 ttcctcgaga gctttacgaa ccaaacttcc ggtggtaccc gtacaaacaa tatggtggtg
     3541 agacaagaac tctgcgttat gtaccgccca ttctaccatt tccgccttac gattgtcgtg
     3601 cgctacaagc gcgatagtca actttttcat accctttacc tttttaatta ttaatcctct
     3661 atcttgttca gcatcttcaa tgtcgccttg atcgccgcct cggtctggtc agcgtccaga
     3721 ccacgagtct tgaaatcgac cccggcataa ttccagctga tgaccgtctg cacaaacgcg
     3781 tccgtacgtc ctcccggcgg gatggatacc gaatagttcg tcaacatcgg gaacgggcgg
     3841 ttcaaacggg aataaatccg gcgtaaggca cgaacgaaag cgtcgtattg tccatcaccg
     3901 gaagccgatt cctcgtaagc ctcgccattg atctcgatct tcaaggtagc taccggtttc
     3961 aacccttggg ccaaggataa ggaatagttc aagatcctga ttttctgatc ctccagcgca
     4021 ttatcatgat gaagcacatc gctgataata taaggaagat cctccggggt aaccatttct
     4081 ttcttatcgc ccagctcaat gatccgctcc gtaaccttac gcatcgaacc ctcgtccatg
     4141 tcgataccga gcgcttccag attcttgcgg atattcgctt ttccggaggt cttgcccaaa
     4201 gcgtactcgc gaacccgtcc gaaacgctcg ggaagcaagt cattgcaata caggttgttc
     4261 ttactatcac cgtccgcatg gacaccggcg cactgcgtaa acacatgctc tccgataatc
     4321 ggcttattgg gcgggatatg cacccccgaa taggtctcga ccaaacgact ggccttgttt
     4381 atcttttcct ccctcaagtt cgtctcctct cccaactgat ccttgatcac agcaaggacg
     4441 ctgctcaatg gagcattacc cgcacgctct cccaaaccgt tcacggtcgt atggattccc
     4501 ttgatacccg cacggatggc ggaatataca ttcgctacgg caagatcata gtcgttatgc
     4561 gcatggaagt caaaccgtaa atccgggtag cggtccacca tcatcttgca atactcgtag
     4621 gtatttccgg gattcaagac tcccaaggta tccgggagca tgaaacggcg gatcggaagt
     4681 cctttcaacg catcgattac caagaataca taattcgggg aatgcttgat accgttcgac
     4741 cagtcctcca aatagatatt cacgtcgatc ttccgtttcg ccgcttccaa tacgaccgta
     4801 cgaatatcgt caacgtgttg ctcgggagtc tttcgaagct gttcggtgac atgcttataa
     4861 gagcccttgc aaagtaagtt cacgacacgg caacctgcgg attcaatcca gtcgagagag
     4921 accgtaccat ccacgaaacc caagacctcc aatttgtcta ggtttccgga acgggcggcc
     4981 caagcggcta cacgcttcac ggcctcaaac tctccgtccg acacacgggc ggaggcgatc
     5041 tccacccggt tcacgcctaa gtcgctcagc agcacttgcg ctatgctaag cttctcgtga
     5101 gcggcgaagg agacgcccga agtttgctcc ccatctctga gggttgtatc cattatttct
     5161 atcataatca gcgtgctgcc tcgaaggctt ctatctttga tttatttgcc agtaaatagt
     5221 cgatatcgtc caatccgttg atcaggcaat cctttttata ggcgttgatc tcgaaatgct
     5281 cgcttttgcc cgtagccttg ttcgtgatcg tttgctccgg tagatttacc tcgacctcag
     5341 ttttcgggtt cttgtaaatc gaatcgaaca attcagcgag gaactcttca gtcacaacaa
     5401 ccggcagcac gaagttgttc aactcgttgt ttttatggat atcggcgaag aaactggaga
     5461 ccacgacacg gaaaccgtaa tcggctatcg cccaagccgc atgctcacgg ctggaaccgg
     5521 aaccgaagtt ctttcccgct accaatatct ttccgctata cgtaggatcg ttcaagacga
     5581 atgattcgat cttattacct tccttatcat atcgccaatc ccggaataag ttctcgccga
     5641 acccttcttt ggtagtcgct ttcagaaagc gggctgggat aatctggtcg gtatccacgt
     5701 tctctaaagg aagaggcacg caagtgcttg tgattatatt gaattttgtt ttcatcttat
     5761 gctactttat tagattagtc tttacatcag ttctctcggg tccgtgatct tacctgtcac
     5821 agcggcggcg gcggccacaa gcggccccgc taagatggtg cgcgcacccg gtccttggcg
     5881 gccctcgaaa ttacggttgg aagtggagac cgcatattta cccgccggaa ccttatcctc
     5941 attcatcgcc agacaagcgg aacatcccgg ttgacgaagg acgaagccgg cctcggccaa
     6001 aaccttgtcg atcccctcgg cacgaatctc ccgctctacc tgccaactgc caggaaccag
     6061 ccaaaccgtt acatcatccg ctttcttctt tcctttcacc aaagaggcga aagcacggaa
     6121 atcctcgata cggccattcg tacagctacc taaaaagaca taatccactt tcttacccaa
     6181 catagactcg cctgccttga agcccatata atccaaagac ttcttataag agatacggcc
     6241 tgcctcgggc acgctttcta aggaggggat atttttgctg atactcatac ccatgcccgg
     6301 gttcgtaccg tacgtaacca tcgggtcgat atcctcggcg tgaaaaacga tctccttatc
     6361 gaacttagcg tccggatcac tatacagctg acgccactcg ctcaccttcc gctcccattc
     6421 ctcgcctctt ggggcaaact cacggtcttt caaataatcg aaagtaacat catccggagc
     6481 gatcataccg ccacgggcac ccatctcgat cgaaaggtta cagatcgtca gacgttcctc
     6541 catggtcgta ttacgaatcg ccttgccagc gtactctacg aaatagcccg tagcaccgct
     6601 ggtactcatc ttactaataa tgtataaagc aaagtccttc gccgtaacgc ccggtttgcg
     6661 tacaccatcg atcgtgatac gcatcgtttt cggcttacgc tgcatgatac attgggtagc
     6721 caaggtcatc tccacctcgc tcgtaccgat accgaaggcg atagcgccca tggcaccgtg
     6781 cgtagaagta tgggagtcgc cacaaacgat cgtcataccc ggctgcgtca agcctgtctc
     6841 cggacctacc acatggatga taccattctt cggatgttga agaccgtaat acgtcaagcc
     6901 gaaatacttc gcgttctctt ccaaggtatc cacttgattc ttggatatag ggtcctcgat
     6961 aggcttatct tggttcaatg tcgggatatt gtggtccggc atacaagtga tttgcgcggg
     7021 acggaagggc ttcaatccac gtgcacgtaa tccggcgaaa gcctgcgggc tagtcacctc
     7081 atgacaatac agacggtcga tatacaattg tatggttccg tcgggcaacg tgtccaccac
     7141 gtgtttgtcc cagattttct caaataatgt cttgctcatt gtcttgtcta tttttagtct
     7201 actataaact tattgatggc gtccacgaaa gcctccacgg aagcggcgat aatatcggta
     7261 ttcgcagaga acccataata ggtagccccg ttatactcta cctgcatatg caccttgccc
     7321 gtatcatcgc tacctttatt aatggcttgg atcaagaatt cctgaatcgt catgtcacta
     7381 ttactaatgg cttttttcac cgccttgata cccgcatcaa ccggaccgtt accagctgcg
     7441 gcctcatatc ttcttactcc cgacaaattt aaacaaatac ttgcgactga ttgtactcca
     7501 acaccactag ttacctgtaa atattccaat ttaatacggt gggtggccgt acgatccttt
     7561 ccgaccaaca tcaaaacatc atcatcatta atatctttct tacgatcggc cagtttcaag
     7621 aactcatcgt acaccttgtc caatttctcc tgctccagat ccacacctaa aacatgcagg
     7681 cgatgcttca acgccgcacg accgctacga gcagtcaata cgatcgcgtt atcatcaata
     7741 cccacatcct tcggatcgat gatctcgtag gtttgcgcat tcttcaaaac gccatcttga
     7801 tggataccgg aggagtgagc gaacgcatta cgtccgacaa tagccttatt cggttgtacc
     7861 ggcatattca tcaagctaga aaccatacgg ctcgtactat agatcttatt cgtcgtgata
     7921 ttggtgatga tatcacgttc tttatggctc ttgaaaacca tggcgacttc ttccaatgac
     7981 gtgttacccg cacgctcacc gataccgttt atggttacct ccacctgacg ggctccgttc
     8041 aacacgcctt gtacggtatt tgcggtagcc atgcccaagt cattatggca atgggtggac
     8101 aagatcgcgt tatgtacgcc atccacatgt tccatcagat acttaatctt cgccccgtac
     8161 tcatccggca agcaatatcc tgtcgtatcc gggatattca ctacggtagc cccggccttg
     8221 atcacggcct ccacgacacg ggccagatat tcattatccg tacgcccggc atcctcacag
     8281 tagaattcta cgtcctccac gtacttttta gcgtatttcg tggcggcgat cgcacgctct
     8341 ataatctcct ctctcgtgga gttaaacttg tatttgatat gagaatcaga agtaccgata
     8401 cccgtatgaa tacgtcctcg cttagcgaat ttcagcgctt cggctgccac gtcgatatcc
     8461 ttctccaccg cacgggtcaa ggcacagatg gtcggccaag tcacggcctt tgagatctca
     8521 accacactct taaaatcccc ggggctggag acagggaaac ctgcctcgat cacatcaaca
     8581 cctagctgtt ccaacgcctt agctacttga atcttttcta ctgtattcaa ctggcatccc
     8641 ggaacctgct caccatcacg taaggtggtg tcgaaaataa ataatctgtc tgacataatc
     8701 ttatattctt aatttactaa tatcctatac taactaaaaa agcctctctc acaaggaagt
     8761 gagaaaggct ctttcatata tcgtaatgct cgcaaagcat acagtctcac ttcctatccc
     8821 gttcccagag tagaataatg tttagagaaa taatgagact attttgcaag ttgcgtgtca
     8881 ttgttcttgt ttttattgtt tttgtttgaa cgttgcaaag atacggcctt ttttgatacc
     8941 accaaatata attcgaagtt ttttacagta tatttcttat aaaacgtaag ataaacaatt
     9001 gtatctgtta ctaaataaca ctgcccatcg ttaggtcgta acgatgggca gtataagctg
     9061 cttacgttgc ccatcataaa ggccttatga tgggcagtgt tatgaaatat gtgagacagc
     9121 tcattttaac gagctacgat cttcttcacg aacaagagca gcgtatttcc agataacatc
     9181 aaggaacgca atactgtttt attcttaagc aaggtaagct tctctaccct attgaggaga
     9241 tgagacgggg cacgccccgt ctctacaact gggtaatgag ttaatcctat agacctactt
     9301 ttttccttat caaatatctt attacatgga aattattcca tacatttgcc actgtactaa
     9361 taaataacag ttacgactat gacaaaatta agcaacatcc ccgccaagga aaccacggcc
     9421 aagaccgcaa gaacacgtaa ggccaagacc gaacccgcaa agcccaagtg ggatcccacc
     9481 aagccggtgc aattcacaca agaggagatc tgggaacata tccatgagat cgagaagggg
     9541 ccgttctatc ctattgaaga agtacatcaa agaataagat catggatgga caactatcaa
     9601 ggaaaaaagt aatcggttct cccatttacg aggaaagcct tgagaggatt ttcgtggaag
     9661 gtatagaacg attcggcata ttccaagccc ggaaatatct tgagcacata ttgaatacag
     9721 tcgagaaact ggaaaacgac tatccttatt atcccgaatg ccgacaccta gctacgaaaa
     9781 gccgcatgta ccggaacatc atcctggatt cacaccttat catctaccgc atcaccgagg
     9841 agcgtatcga agtgctagac atcgtccatt ccgcatccag catgcgaaag atcaaacagg
     9901 ctaggaatat ccacatcgaa tgatgcagag aaacagaaaa aggcgagcca cccgtaagtg
     9961 acccgcctct ttttgctgat atataaggat taagattgga ttagttgttc tccggacgaa
    10021 gcttgcgtac ggtaacagct gtctgccaca tctcgctctc gcgcaatgcc ttcaattcag
    10081 cctccaattt ctcacgataa tccggcttag agtttgagtc gatagagatc tgagcctcgt
    10141 taccgcattt tacgttcgcg tacaatttct cgacaaccgg cttgattgcg tcgtggaacg
    10201 gacccatcca gtccaaagcg ccacgctggg cagtcgtaga gcagttcgcg tacatccagt
    10261 ccataccgtt cttagcgaat aaaggcatca aggattgagt caactcctcg accgtctcgt
    10321 tgaaagcctc ggaaggagtg tgcccattct cgcgcaatac ctcatactgg gccaacaaca
    10381 aaccttggat agcgcccatc aaggaaccgc gctcaccggt caagtcggaa gtagcctcac
    10441 ggatgaaagt cgtctcgaac aaataaccgg aaccgatacc gatacccaac gccaacgtac
    10501 gatccatcgc cttgccagta gcgtcttgat agatagcgaa agaagagttc aagccacgac
    10561 cctcaaggaa catggaacgc aaagacgtac cagacccctt cggagcgacc atgatcacgt
    10621 caatatccgc aggaggaaca acgcccgtac gatcgttcca agtgatcgca aaaccgtgag
    10681 agaaatacag ggccttgcca gctgtcaaat aaggcttcat cttcggccat acagacatta
    10741 cggcagcgtc ggacaacaag cacatgatga tcgtggcctt gtcgcaagcc tcctcgatac
    10801 cgaacagagt ctcacccgga acccatccgt cctcaaccgc tttctcgtaa gtcttacctt
    10861 ggcgctggcc aacgattacg ttgaaaccat tgtcacgaag gttcaatgac tgtcccggtc
    10921 cctgtacgcc atagccgatc acagcgattg tctcatcttt taatatctct cttgcctttt
    10981 ccaacggaaa ttcctcgcgg gtcattacat tctctacaac accgccaaaa ttcatttgtg
    11041 ccattttctt tttaactatt aatgtttaaa aacctattta tgtatctctt ttattatctc
    11101 caagtaaccg ccgcacgaca gatcgccttt ccctcatggc aaatagccat gtcttgctta
    11161 tcgggagcgg actccgcctt atgaagcgta agcggcatac cttgtttgcc ctcggattgg
    11221 taggcgatct ccagacggcc gatctcacgg gtcttgaact ggtcaatatc gaacaaatcc
    11281 aaaagatgct caatatactt cacgctattg aagtgaccgt tgatatccaa gtcgctgtat
    11341 ttgatcgaat acgggattcc ctccgcctta ttctccgccg gcatgatctt gcccggcttc
    11401 tcgatcgggc acggacgctc gtcgatatat ttgcccaatg cctctatatc caataaggta
    11461 ggacggcggg tctccacatc gatagccgcc cagatagaac gggcgaatcc aaaggttttc
    11521 ccattctcat ccgccagatc aaaacaacga ctggtgaaga ggcgtccgac ctcatcgatc
    11581 caagtgtata gattaatctt atcgaaggcg gtaggatatt ccttcatctc gatagccaga
    11641 cgggacaaca cccaagccgt atgacgctcc gacatatcat tgaaaccgaa cccacgctct
    11701 ccggcatggc tggaagcggc gtgaatcaaa tagttaccaa tcatagggag cgttacacgt
    11761 cccctgaaat ccatcaaata cggctccgcc acgaaatgaa ataatcctac tttctccata
    11821 tcttattatt gttgcttttc atgtaacttt cgctccatat cggccaacat atcgctcaag
    11881 cgctccacct tgctcttcgt gatagccaca cgtccggagc ggatgaattg caggacaccg
    11941 atcgtctcgc tcaactcatt gaacaaggct tgtgtctcgt catagtggcc actcttctcc
    12001 aataccacgc aggtctcgtt catctccaag atacgagcgt tgtatttacg gatcaatccc
    12061 tccacggttc ccatcttgat gaaaagctcg gtacttagct tataaagagc gatctcttga
    12121 taaaccagat cctcatccgt attataataa gccttcaaga tatccacacg tttatcgatc
    12181 tgtttcacca ccttatcaat catatcctca tcggcgaatg tcgtgatcgt aaacttatgg
    12241 atgcccttga tagcggacgg agagacggac agagtctcga tgttcagctg tcggcgtgta
    12301 aagataatcg ttatctggtt caaaagacct acgatattct ctgaaaagat aataacggta
    12361 tataatttct ttgttgtcat agcttcatct cctccttatt tctcgtctcc caaaatcatg
    12421 tttgtcacgc ttcccccggc tggaaccatc ggatatacca ttccgcaagt ctccacgtta
    12481 gcgaccaaca cgtaagcacc gtcgtggttt agcatctcag cgatagcgtc gtccaattcc
    12541 tcccgctttt caacagcacg accggcgata ccataggctt tagcgatcgc cacgaaatcc
    12601 ggattctcca tgatggtgtt tgaataacgc tcgtggaaga acaattcttg ccactgacgt
    12661 accataccta agaagttatt attaagaatg ataatcttca cgttcagttt ctcctgcatg
    12721 atggtaccca attcttgaat cgtcatctgc atacccccat caccggtaaa gaagcagacc
    12781 gtacggtccg gagccccgaa cttagcaccc atagcggccg gcagaccaaa tcccatcgta
    12841 cctaaaccac cggaagtcac cacgctacgg gtttgtttat atttgaaata gcggacgccc
    12901 atcatctggt tctgcccaac gtcggtcacc aatacagcat cgttaccggt cgcctcggaa
    12961 accttacgga ctacctcgcc cattttcagt tggccctcgg tcggatacaa ttccttctcg
    13021 attaccttat cgtattcctc tttctcgtcc cgatcgaact cggcattcca ttccggacgt
    13081 ttacgttctt ccaacaacgc cgtgatcatc ggtatcgtgt gcttggcatt ccccagcacc
    13141 tttacgtcca cggcaacatt cttgccgatt tctgagttgt cgatatccag atggataatc
    13201 ttggcttgct tagcgtatgt ctttaaatcg ccagtcacac ggtcgtcgaa acgcataccg
    13261 atagcgatca atacatcaca ctcattcgt
//
