LOCUS       c00001_gnlPro..        16226 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MHFPLCIJ_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 17:31:33
            Original ID  :: gnl|Prokka|MHFPLCIJ_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16226
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16226
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3270:6226]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3271..6226
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16226
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16226
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(508..1038)
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MDLQIIQNKIFEVRGCRVMLDYHLAELYQVETRALKQAVKRNIER
                     FPSDFMFVLTKEEANLLLSIGVSQNVIPPDYNFGVAMPMAFTEQGVAMLSSVLRSKIAI
                     EVNISIMRAFVLMRQMVIGYEELLRRIEELEVSTDAQFNELYQALTQLLSQSKQQKERR
                     PVGFVTYNRDKDE"
     CDS             complement(1123..2358)
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MKSTFNICFYAKKDKQKANGAYPLFARITVDGVASRFNTKLDVLP
                     SIWDGKMGKATGRTSEASRINRMLDDINASLNTIYHEMQRRDNYVTAEKVKNEFLGHSE
                     SHETILTLFQKHNDDVKQLVGISKTIATYRKYEVTRRHLAEFIQSKYNVSDISIKEISP
                     MFITDFELYLRTACKCGYNTTAKFMQFFKRIIIIARNNGILVNDPFASYKIRLEKVDRG
                     YLTEDEIKIILKKKMVSERLEHVRDLFIFACFTGLAYIDVAGLTQDNIRKSFDGNIWIM
                     TKRQKTNTDVNVPLLDIPKMILKKYKGKLPNGKILPVISNQKLNAYLKEIADICGIKKN
                     LTFHLARHTFATTTTLSKGVPIETVSKMLGHTNIETTQIYARITNSKIGSDMQGLDKKF
                     VGIEKIYKEVAM"
     CDS             3271..5499
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3"
                     /sec_met_domain="Gly_radical (E-value: 7.9e-46, bitscore:
                     148.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1169.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFTNGLWNKEINVSDFVSKNIAPYTGDASFLQGPTERTKR
                     IWDICLKALEEERNNNGVRSLDNTTVSTITSHKAGYIDKDNELIVGLQTDELLKRSIKP
                     FGGINVVAKACRENGVEVDDKVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGIDRLIEAKQEDLRNLTGPMTEARIRLREEVAEQIKALKDIK
                     VMGEYYGLDLSHPATSAQEAVQWVYMAYLAAIKEQDGAAMSLGNVSSFLDIFIEYDLAH
                     GKINETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTEAIGGRFNDGRVKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKDFCAKVSVDTSSIQYENDNLMREVRNC
                     DDYGIACCVSYQAIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKGIPVLTGETL
                     KFEEVMANYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMAFIDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAKVTARRNEIGLTEGFDTEGSFPCFGNNDDRVDHLGVDLVYYFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGPTPEERVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             5501..6226
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 75.5;
                     E-value: 1.7e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4"
                     /sec_met_domain="Radical_SAM (E-value: 2.1e-30, bitscore:
                     99.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCPFRCLYCANPDTIDVKGG
                     TPTTPEEILQMAISQKAFFGKKGGITFSGGEPTLQAEALIPLFKELKANGIHICLDSNG
                     GIWNEKVEELFSLTDLVLLDIKQFNPERHRTLTGRSNEQTLRTAAWLEEHEHPFWLRYV
                     LVPGYSDSEEDTRLLGESLGKYQQIQRVEILPYHRLGVHKYEAMGWDYKLKEVKENTPE
                     QLERAEKLFKEYFTNVITN"
     CDS             complement(6295..8499)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 84.6; E-value: 1.3e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg1_5"
                     /sec_met_domain="Fn3-like (E-value: 2.9e-26, bitscore:
                     84.6, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 5.2e-74, bitscore:
                     242.6, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 1.1e-51,
                     bitscore: 168.9, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIILMVCLWGLGNTFTSAQTTEKEKFISSLMKQMTLDEKIGQ
                     LAQCTYRGNFTGPDGGNIPKEEYVRQGRIGSMLNVIGVKDIRRYQELALQSRLRIPLIF
                     GLDVIHGYRTGFPLPLAEAASFDLAMIEEAARYNALESAADGLNWVFAPMVDISWDARW
                     GRVMEGAGEDPYYGSRVAEARVRGLQGDDLADTTTVMACMKHFAGYGAPIAGKEYNSVD
                     MSMGHFANFYMPPYKAAIKVGAATVMSAFNDFNNIPCTANDFLLNRLLREQWGFKGFVV
                     SDYNSVEELVNHRYAVDKKDAAAKALNAGLDMEMVSTCYLTYLKELVQEGKVKESVLDD
                     AVRRILEKKYELGLFEDPFRYCNPERAARILNAPEVRNASLRMAERSVVLLENRESVLP
                     LTAQTRKIALIGGLSKSQYDMAGAWAATTDRNKVVTLYDALVRKGLEVSYAEGYDMKSN
                     QLTGLQEALQAAEASDVIVVAVGERFGQSGEKASKVNIAIPEGQQKLVSELAKTGKPVI
                     ALVMCGRPVIFNEIREHADAVLCTWWLGSEAGNAICNVLWGEYNPSAKLPMTFPAHVGQ
                     IPIYYQNKSTGRPTALKQTYKASYIDASTEPAYPFGYGLSYTDFGYSDLKLLPGKAAGV
                     HTEVSVKVTNTGKCAGEEVVQLYVQDKVASVTRPIKELKGFRKIHLNVGESKTVAFQIT
                     DDALGFYDNEMNYMVEPGDFVFMVGGSSDDVQQITYNLKE"
     CDS             complement(8530..10992)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 80.1; E-value: 3.4e-25)"
                     /gene_kind="other"
                     /locus_tag="ctg1_6"
                     /sec_met_domain="Fn3-like (E-value: 7.8e-25, bitscore:
                     80.1, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 8.2e-56, bitscore:
                     182.8, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 5.3e-50,
                     bitscore: 163.4, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKKKVALSGLLLCCAITAKAQVCITPQVEQRARELVSQMTLEE
                     KIDYISGPKSFYIRAVPRLGIPEIRMADGPQGIRNNTQSTLYPCGILSASTWNRKLARE
                     LGHGLARDAKARGVSILLGPGVNIYRSPLCGRNYEYFGEDPYLTGETAKEYILGVQEEG
                     VMATVKHFAANNQEWSRHHASSDVDERTLQEIYFPAFRKAVQEAGVGAVMDSYNPLNGV
                     HATENSWLNIDVLRKQWGFKGILMSDWTSVYSGVGAANGGLDLEMPVGKFMTREILIPA
                     IENGIVKEETIDAKVRHILQTLIAFGALDTPREDKSIDKDNAQSKEIALDLAREGVVLL
                     KNDNGTLPYRNGRTLVIGPNADIIPTGGGSGFVTPYSVVSLYDGMVQLKGGRQIELLSD
                     SILYKDMSQQIYTDGSFTQNGFKGEYYNTRNLTGELFQAAIEPAIDHAWKYGAPFDGMP
                     VDQFSARWTGVYKADKDGTVKFQLAGDDGYRLFVNDKLITGDWGNHSFSTRSAFMQVSA
                     GEIYRLRIEYFDNVGEATVSFQAGMMDEERLASSLKHARNVIVCAGFNSSTEGEGFDRP
                     FALSYGQEYLINKVASLHDNVAVVVNAGGGIDFRNWGQSVQAILMAWYPGQEGGKALAE
                     IITGKLSPSGKLPVSIEEKWEDNPVYGNYYDNRNVPHKRVQYAEGVFVGYRGYDRNGKQ
                     PLYPFGYGLSYSSFEYSNLSVEKTGGSRVTVSFDIKNTGKMDAAEAAQVYVRDVECSVP
                     RPLKELKGYDKVYLKKGETKRVRILLDEEAFAYYDVESHRFVVEKGTFEILAGPSSADL
                     PLKATVVL"
     CDS             complement(11169..12482)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MEDELWLKKIKDKLEDYSEPLPVAGWERLEKELSVSGAPITGPHR
                     MIPFRRWAVAAAAVLLVAVSSVSLWLLQSPVGNEMRHTSVPALAVAPDVLPEQTVPAIR
                     TNSIEPAYRAHGNASAPNKEASHPLVAQHIRISVGEEQQEEMLPVETADEVVGIGQQAE
                     EPVVEDTDHETTMQTEEPETREDRYRPSGRDKLHLPEKNSSGRDAKGWAVGLSVGNTGG
                     FSLANEGEANVMSDYMPGSPIYGGNVDLSSTANGIVTIPDGQELVFKDGMPYLQRREKK
                     IADIDHKQPLSFGVSVRKNLAKGFSVESGLTYTYLASDVRYEGSSEKISQKLHYIGIPV
                     RANWNFVDAKNFTMYVSAGGAIEKCVYGKIGTESETVKPVQLSVMGAVGAQYNISNRVG
                     LYVEPGVSYFFDDGSSIQTIRKENPCNFTLQAGIRLTY"
     CDS             complement(12495..13043)
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MEEQELAERCRQGDNLARKELYERYAGRMLSVCLRYAGDRETAQD
                     LMHDGFLKLFDSFDKFTWRGEGSLRAWMERVMVNTVLQYLRKNDVMNQSSALENAPEAY
                     EEPEGSSIDVIPQKVLMQFISELPAGYRTVFNLYIFEEKSHKEIARLLGINEKSSASQL
                     TRAKATLAAKVREWMKRND"
     CDS             13224..13928
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MKKLRMTLATSMLLFLTAIVLQSCLDDWDDKYDTLFAVGTVKVIE
                     GKDYYFSLDEGSKLYPSDTTYVHDYAVTDGQRAFIYFRELEEKLPGYEYNAQIKHIENI
                     LTKDIYSMPAEKADSIGDDNINATDLWITGEYLNIKYQFYHSNNEDKKHMLNLVINEAS
                     TGENDKPDYVNLEFRHNAYNDSQLTLGTGLASFKLDNIAEQLKEKKGLNIRVKSLYDGE
                     RFMTIDIKKENN"
ORIGIN
        1 tttaaggggg cattgttgaa tgttttaagg gggcagaatc gcttggtttt agggggcagc
       61 ttacactgga ttttccagca gggaagattt tttcaccaaa ccggaacggc tcgaccttgc
      121 aaagtcgtga agaacacgta actacctttg cctattgaaa tgataaaaac gactgtcccg
      181 gctggggact gcataatgag gaggatttac agatagggaa acagggaaaa agtgcttgtt
      241 ccctttcatc ctttagggaa cactccatgc gggcgggaaa ggcaagggta tggcaagttc
      301 accttgcggt acgcttgtgc ggatttccaa cggctctttt cacgaaatac agtcagccat
      361 gccacgcacg gctggcgttt cggggaatgt gccagttgga aaagggaata aaaaatgcgg
      421 gtagtcggtg gactgcccgc aaggtggaag aatgtacttt attgggatat agcttgttag
      481 gcggaaaatc gttaccgaaa tcgttaccta ttcgtctttg tcacggttat aggtaacaaa
      541 acctaccgga cggcgttctt tctgttgctt cgactgactt agaagctggg taagggcttg
      601 atatagctcg ttgaactgtg catcggtgct tacctccagt tcctcgatgc gccttaacag
      661 ttcctcgtag ccgattacca tttggcgcat gaggacaaaa gcccgcatga ttgaaatgtt
      721 cacctctatg gctattttgg aacggagaac cgaagaaagc atggctacgc cctgttcggt
      781 gaaagccata ggcatggcta caccgaagtt ataatcagga ggtatcacat tttgtgatac
      841 ccctatggac aacaataagt tagcttcctc tttggtgaga acaaacataa aatcactggg
      901 aaaacgctcg atattgcgct tgaccgcctg cttcaaggct cgtgtttcca cttggtagag
      961 ttctgccaaa tgataatcga gcatcacccg gcaacctctg acttcaaaaa ttttgttttg
     1021 gataatctgt aagtccataa tcgtatattt taggagattt agtaatgttg gaataatagt
     1081 aaggactggt cacaaattgt gaccagttac caacaatcaa gattacatag cgacttcctt
     1141 gtaaatcttc tcgatgccga caaacttctt gtcaagcccc tgcatatcac tacctatctt
     1201 gctgttagtg atgcgggcat agatttgggt cgtttcaatg ttcgtgtgtc ccaacatttt
     1261 agacaccgtt tcaatgggta cgccctttga cagcgtggta gtcgttgcga acgtgtggcg
     1321 ggcaaggtga aatgtcaagt tctttttaat accacatata tcggcaatct ctttcaagta
     1381 ggcgtttagc ttctgattgc tgattacggg aagtatcttg ccattcggta acttgccctt
     1441 gtacttcttc aaaatcatct tgggaatatc cagcagagga acattaacat ccgtattcgt
     1501 cttttgccgc tttgtcatta tccaaatgtt gccgtcaaaa gatttgcgaa tgttgtcttg
     1561 cgtaagcccg gctacatcta tataggcaag cccggtgaag caggcaaaga tgaacaagtc
     1621 cctgacgtgt tccagccgct cggaaaccat tttctttttg aggatgattt taatctcgtc
     1681 ctctgtcaga taccccctgt ccactttctc cagccggatt ttgtaactgg cgaaagggtc
     1741 gttcaccagt atgccattgt tgcgggcaat gatgatgata cgcttgaaga actgcatgaa
     1801 cttggcggtg gtgttgtagc cgcacttgca ggcggtacgc aaatacaatt caaaatcggt
     1861 aatgaacatc gggcttatct ccttaatgga tatgtccgat acgttgtact tgctttgaat
     1921 gaactcggca aggtggcggc gggtgacttc atacttgcgg taagtcgcta ttgtcttgga
     1981 tatgccgacc aactgcttca catcgtcatt gtgcttttgg aacagggtaa ggattgtttc
     2041 gtggctctcg ctatgaccta aaaactcgtt cttcactttc tcggcggtca cgtagttgtc
     2101 acgccgttgc atttcgtggt aaatggtgtt caaggatgcg tttatatcgt ccagcatacg
     2161 gtttatgcgg ctggcttccg aagtacgtcc ggtagccttg cccattttgc cgtcccaaat
     2221 agagggcagc acgtccagct tggtattaaa acggctcgcc acgccgtcca ctgtgatacg
     2281 ggcgaaaagg gggtacgcac cgttggcttt ctgcttgtct ttctttgcgt aaaagcaaat
     2341 gttgaatgtc gatttcataa ctcacttttt aaattgcaaa actattgtaa ttctctaaaa
     2401 atgagttcta tgcaggcaag ccaaatagcg acaggacttc gccaatttcg gacaatctgt
     2461 accccctttc cgtttttgtt tgtcgggggt acgagttagg ttacgaactt tgtctttttg
     2521 gggcgaaaag gtgtacttta aggcagacac aagggaataa aaaaagtccc acaaatcatt
     2581 gaatttgtgg gacttgtctg cttactgtcc ggtattgtcc ggttagtttt gcggagagac
     2641 agggattcga accccgggtg cctcgcagca caacggtttt caagaccgcc gcaatcgacc
     2701 actctgccac ctctccaaaa cttctttttc agaagtgctt ttcttttaaa gcggtgcaaa
     2761 gatacaaatc attttttatt ctacaaactt ttctgcacaa aaacagagca attataccaa
     2821 aattcttgtt tatacccact acggaacgaa cataacggca tttaggctat ttgttgaaat
     2881 ttatcaaggg caagacagag ttttataact tactggctat cagtatattt acaaagagcc
     2941 acattcagta tacgattgaa ccctattcag tatacgactg aatggcattc actatacgac
     3001 tgaattaggt tcagaatacg actgttcctt aaacctacat catttgtaaa taatgcagat
     3061 tattattcgg ttcttgtttc aattcataaa ccacatataa agaaagtatt aacatctcta
     3121 ctcccccgga cattcactac ctaataatag ttattttatg ctgttcaaca taaaaagaga
     3181 agtatctctt ataaaattac ggaatttatt cagtattttt gcgcgctcta aaggataaca
     3241 ttatctaacc tactaacaaa aacaaatttt atggaattga acaaaacctt taccaatggg
     3301 ctttggaata aagaaatcaa tgtcagtgat ttcgtcagta aaaacatcgc accctatacc
     3361 ggggatgcat ctttcttgca gggacctacc gaacgtacca aacgtatctg ggacatctgt
     3421 ctgaaggctc tcgaagaaga aaggaacaac aatggcgtcc gttcactgga caataccacc
     3481 gtatctacca tcacttctca taaagccggg tatattgata aggacaatga acttattgtc
     3541 ggtttgcaga ctgatgaact gttgaaacga tccatcaaac ctttcggagg catcaacgtg
     3601 gtagcaaaag catgccgtga aaacggagtg gaagtggacg ataaagtaaa agacatcttc
     3661 acccattacc gcaaaacaca taacgacggc gtattcgatg tatataccga agaaatccgt
     3721 tccttccgct cactgggatt ccttaccgga ttgcccgaca actatgcccg cggacgtatc
     3781 atcggcgact accgccgatt ggctctctac ggcatcgacc gtctgattga agccaagcag
     3841 gaggacttgc gcaacctcac cggcccgatg accgaagcac gcatccgtct acgcgaagaa
     3901 gtggcagaac aaatcaaagc tttgaaggac atcaaggtta tgggcgaata ttacggactc
     3961 gacctcagcc atccggctac atcagctcaa gaggccgtgc aatgggtata catggcatat
     4021 cttgctgcca tcaaagagca ggacggagca gccatgtcac tgggtaacgt atcttcgttc
     4081 ctcgatatat tcattgaata cgatctggct cacggaaaaa tcaatgagac gtttgcacag
     4141 gaactgatag accagttcgt catcaagctg cgcatggtac gccatctgcg tatgcaatca
     4201 tacaatgata tctttgccgg tgacccgact tgggtgaccg aagccatcgg aggacgcttc
     4261 aatgacggac gcgtgaaggt caccaagact tctttccgct ttttgcagac gctatacaac
     4321 ctcggtcctt ctccggaacc gaacttgacc gtattgtgga gtcccgaact gccggaaggc
     4381 ttcaaggatt tctgcgccaa agtttctgta gataccagct ccatccagta cgaaaacgac
     4441 aacctgatgc gtgaagtgcg caactgcgac gactacggca tcgcctgctg tgtatcctac
     4501 caagccatcg gcaaacaaat ccagttcttc ggcgcacgtg ccaaccttgc caaggccctg
     4561 ctgctcgcca tcaacggtgg acgttgcgaa aataccggaa ctgtcatggt gaaaggtatt
     4621 cccgtattga ccggtgagac attgaagttt gaggaagtta tggccaacta caagaaggta
     4681 ctgactgaaa tagcccgtgt ctacaacgag gccatgaata tcatccacta catgcatgat
     4741 aagtattatt atgagaaagc ccagatggca ttcatcgata ccgacccacg catcaatctg
     4801 gcatacggtg ttgccggcct ttccatcgcc atagactcac tgtccgccat caaatatgcc
     4861 aaagtcactg cacgccgcaa cgaaatcggc ctgaccgaag gtttcgacac tgaaggttca
     4921 ttcccctgct tcggcaataa tgacgaccgt gtggaccacc tgggagtaga cctcgtttac
     4981 tatttcagcg aagaactgaa aaagctgcct gtctacaaga atgcccgtcc caccctttcc
     5041 ttgctgacta tcacctccaa cgtgatgtac ggcaagaaga ccggtgccac tccggacgga
     5101 cgcgccaaag gtgttgcctt tgctccgggt gccaacccaa tgcacggacg tgacaagaac
     5161 ggtgccatcg cttccttgag ctccgtagcc aaattgcgct accgcgactc gcaggacggc
     5221 atcagcaata cgttctccat tgttcccaaa tcactgggcc cgacaccgga agaacgtgta
     5281 gagaacctgg taaccatgat ggacggctac ttcaccaaag gtgcccacca tttgaacgta
     5341 aacgtactga accgcgaaat gctggaagat gccatggaac atcctgaaaa gtatccgcaa
     5401 ctcaccatcc gcgtttccgg ctatgccgtg aacttcgtga agttgagccg cgagcatcag
     5461 ttggaagtca tcagccgttc attccacgaa agaatgtaat atgataaatg tacactccta
     5521 cgaaagtatg ggaacattcg acgggccggg tctccggctc gtcgttttcc tgcaaggatg
     5581 tccgttccgt tgtctgtatt gtgccaatcc ggatacgatt gatgtaaaag gaggcactcc
     5641 caccactccg gaagagattc tgcaaatggc tatcagccaa aaggcattct tcgggaagaa
     5701 aggaggtatt actttctccg gcggtgagcc taccctgcaa gcagaagcgc tgattcctct
     5761 tttcaaggag ctgaaggcga acggcatcca tatctgtctg gacagtaacg gaggcatctg
     5821 gaatgaaaag gtggaagagc tctttagcct gactgacctc gtgctgctgg acatcaagca
     5881 attcaatccc gaacgccacc gtacgctgac gggacgaagc aacgaacaga cactccgcac
     5941 cgctgcctgg ctcgaagaac atgaacaccc cttctggctg cgctatgtac tggtccccgg
     6001 ttacagcgat tcggaagaag acacccgcct gctgggtgaa agtcttggca aataccagca
     6061 gatacaacgg gtggaaatac ttccttatca ccgtctgggt gttcacaaat acgaagccat
     6121 gggatgggat tacaaattga aagaagtgaa ggaaaatact ccggaacaac tggaacgggc
     6181 agaaaaactg ttcaaagagt atttcacgaa tgtgataacc aactaaaaca gaaaagcaag
     6241 gctgtccgga tatgattcca gacagccttg cttttcattt atagggtaag aatcctattc
     6301 tttcaagtta taggtaatct gctgtacatc atcactactg ccacccacca taaagacgaa
     6361 atcaccaggt tctaccatat aattcatctc attgtcatag aatcccagtg catcgtcagt
     6421 tatctgaaaa gctacagttt tgctttcacc cacattcaga tgaattttcc tgaagccctt
     6481 caattccttt atcggacgcg taacagaggc taccttatcc tgcacataca attgaactac
     6541 ttcctctcct gcacacttac cggtattagt cacttttacc gacacctccg tatggacgcc
     6601 tgcagccttg cccggcagca gtttcaaatc agaatatcca aaatccgtgt acgaaagccc
     6661 atatccgaaa ggataggcag gctcagtgga agcatcgata taagatgcct tataggtctg
     6721 tttcaatgcg gtagggcggc cggtgctctt attctgataa taaatgggaa tctgtcctac
     6781 gtgtgcagga aatgtcatgg gcaatttagc cgaaggatta tactctcccc acaacacatt
     6841 gcatatggca ttgccggcct cacttcccag ccaccaagta cacagtaccg catcagcatg
     6901 ttcccttatc tcattgaaga ttaccggacg cccacacatg acaagagcaa tgacaggttt
     6961 tccagtcttt gccagttccg acaccagctt ctgctgcccc tcgggtatgg ctatattcac
     7021 tttggaagcc ttctcgccac tctgaccgaa tctctcgcct accgccacaa caatgacatc
     7081 cgaagcctca gcagcctgta atgcttcctg caatccggtc aactgattgc tcttcatatc
     7141 atagccttca gcatagctca cctccagtcc tttccggacc aatgcatcat ataaggtcac
     7201 cactttgttc cggtccgtag tggcagccca agcacctgcc atatcgtact gggattttga
     7261 gagtcctcct atcaaggcta tcttcctcgt ctgtgccgtc aacggaagca cagattccct
     7321 attctccagc aatacaacgg aacgctcggc catacggagc gaagcattac ggacttcggg
     7381 cgcattgagt attctggccg ctctttccgg attacagtag cgaaaagggt cctcaaacaa
     7441 tcccaactca tatttcttct ccaatatacg ccgtactgca tcatcaagca cactctcctt
     7501 tactttccct tcttgaacaa gctccttcag ataagtcaag tagcaggtac ttaccatctc
     7561 catgtccaga ccagcattca gcgctttggc tgcggcatct ttcttgtcaa cagcataacg
     7621 gtggttcacc aattcctcta ccgaattata atcggacaca acaaatccct taaatcccca
     7681 ctgctctctc aatagccggt tgagcaagaa atcattggca gtacaaggaa tattattaaa
     7741 atcattgaaa gcactcatca cggtagctgc tcctaccttt atggccgcct tatagggagg
     7801 catataaaaa ttggcaaagt ggcccattga catatccaca ctattatact cctttcctgc
     7861 tatcggtgca ccatatccgg caaaatgttt catacatgcc atgacagtcg tcgtgtctgc
     7921 caaatcgtct ccttgcaagc ctctgacacg cgcctccgct acccgagaac cataataagg
     7981 gtcctcaccg gccccttcca tgacgcgtcc ccaacgtgcg tcccacgaaa tatccaccat
     8041 cggggcaaaa acccagttca aaccatcagc ggcactttcc aaagcattgt agcgtgcagc
     8101 ttcctcaatc atggccaaat cgaaacttgc agcctcggca agcggaagcg gaaatccggt
     8161 acgatagccg tggataacat ccagtccgaa aattaaagga atgcgcaaac gcgattgcaa
     8221 agcaagctct tgataacggc gtatatcctt tactcctatc acattcagca tagagcctat
     8281 tctgccttgc cggacatact cttctttagg aatatttcca ccgtcgggtc cggtaaaatt
     8341 ccctcggtag gtgcattgtg caagctggcc tatcttttca tccagcgtca tctgcttcat
     8401 caagcttgag atgaatttct ccttctccgt agtttgtgcc gaggtaaagg tgttaccaag
     8461 tccccacaga caaaccatca gtattattat ctttttcata ctgccattct tgttttgata
     8521 tttattttat cataaaacaa cagttgcctt caatggtaaa tcagctgaag aaggacctgc
     8581 cagaatctca aaagtcccct tttccactac aaaccgatgt gattccacat catagtaggc
     8641 aaaggcttcc tcatccagca atatccgaac gcgcttggtt tcacccttct tcaagtaaac
     8701 cttatcgtag cctttcaact ccttcaatgg acgcggaaca gaacattcca catcccgcac
     8761 atatacctga gccgcttccg cagcatccat ctttccggta ttcttgatgt caaagcttac
     8821 cgtaacccgg cttccccccg tcttctcaac actcagatta ctatattcaa aactactgta
     8881 tgacagtcca tacccgaaag gatagagcgg ctgctttccg ttccggtcat atcccctata
     8941 acctacgaaa acaccttcgg catactgcac ccgtttatga ggtacattgc gattgtcata
     9001 ataattacca tataccggat tatcttccca tttttcctcg atgctgactg gtagtttgcc
     9061 acttggcgaa agcttgcccg taatgatttc ggcaagggcc tttccaccct cctgccccgg
     9121 ataccatgcc atcaaaatag cttgtacact ctgcccccaa ttgcggaaat ctattccacc
     9181 tccggcattc accaccacag ccacattatc atgaagtgaa gccactttat taatgagata
     9241 ttcctgcccg tatgacaatg caaacggacg gtcgaaccct tcaccttctg tactgctgtt
     9301 gaacccggca catacaataa cattcctggc atgcttcagt gaagaggcca aacgctcctc
     9361 atccatcatt cctgcctgga aactgacagt cgcctcaccc acattatcaa aatattcaat
     9421 acgcaaccgg tatatctccc ctgcactgac ctgcataaat gcactgcggg tactgaatga
     9481 atggttcccc caatctccgg taatcagctt atcgtttaca aacagacggt atccgtcatc
     9541 gccagccagc tggaacttga cagttccatc cttgtcagcc ttgtaaactc ccgtccaacg
     9601 ggcagaaaac tgatctaccg gcatgccgtc gaacggtgca ccgtatttcc aggcatggtc
     9661 tatggcaggc tctatggcag cttgaaagag ttctccggta agattacgag tattataata
     9721 ttcgccctta aaaccgtttt gcgtaaaact gccatccgta taaatctgtt gggacatatc
     9781 cttataaaga atgctgtcag acagcagctc tatctgtctg ccgcccttca actgaaccat
     9841 accgtcatag agtgacacta ccgaataagg ggtgacaaat ccgcttcctc ctcctgtggg
     9901 aataatatcg gcattaggcc cgattaccaa tgttctaccg ttccggtaag gcaacgtacc
     9961 gttatcattt ttcaataaga ctactccttc tctcgccaag tcaagtgcaa tttccttaga
    10021 ctgtgcattg tctttatcga tagatttatc ttctctcgga gtatcaagtg ctccaaaagc
    10081 aatcaatgtc tggagtatat gccggacttt ggcgtcaatg gtctcttcct tcacgatacc
    10141 attctctatt gccggaataa gaatttccct ggtcatgaat ttaccgacgg gcatttccaa
    10201 atccaaccct ccattagcgg ctcccacacc agaatataca gatgtccagt cagacatcag
    10261 gataccttta aatccccact gcttgcgtaa tacatcaatg ttcagccagc tgttttcggt
    10321 ggcatgtacc ccgttcagcg gattatagct atccataacc gcccctactc ctgcttcctg
    10381 cacagctttt cggaacgcgg gaaaataaat ttcctgcagc gtgcgttcat ccacatctga
    10441 gctggcatga tgtctgctcc actcctggtt attggccgca aaatgcttca ccgtagccat
    10501 aactccctct tcctgcactc ccaagatata ttctttagca gtttcgcccg tcaaataagg
    10561 gtcttcacca aaatactcat agtttcgccc gcatagagga gagcggtaga tattgactcc
    10621 aggccccaac agaatactta ccccacgggc ctttgcatcc cgggccaaac catgtcccag
    10681 ctctctagcc aacttacggt tccatgtcga agccgacaag atgccacaag gatacaaggt
    10741 actttgagta ttgttacgta tgccttgcgg accatcggcc atcctgattt cgggtatgcc
    10801 aagccggggt acagcccgga tataaaaaga tttgggaccg gaaatgtaat cgattttttc
    10861 ttccagcgtc atttgagaaa ccaactccct ggcacgctgc tccacctggg gagtaataca
    10921 cacttgtgct tttgccgtga ttgcacaaca aagcaatagc ccgcttaagg ctactttctt
    10981 tttaatcttc attttgtcta ttttactacg tgtttgttat attgccgggc atgtcccgac
    11041 ctactttctt tcttctcaat caataaaaaa ccgtgtccct tcatccacca acgaagaaac
    11101 acggccgaaa gttattaaga aaattctgaa tctacaagaa agtggacaaa aacatgtctg
    11161 tcctgctatc aataagtaag acgtataccg gcctgcaacg taaagttaca cgggttctcc
    11221 ttgcgtatag tctgtatcga cgaaccgtca tcaaagaaat aagatactcc cggttccaca
    11281 tacaggccca ccctattgct tatgttatac tgggcaccga cagcacccat gacagaaagc
    11341 tgtaccggtt tcacagtctc actctcagta ccaatcttgc catacacaca tttttcaatg
    11401 gcaccccccg ccgaaacgta catcgtaaag ttctttgcat ccacaaagtt ccagttggcc
    11461 cgtaccggaa tgccaatata atgcagcttc tggcttatct tttccgagct gccctcatac
    11521 cttacgtcag aagcaagata ggtatacgtc agcccgcttt ccacagagaa acccttcgcc
    11581 aagtttttcc gcaccgaaac accgaaactg agcggttgtt tatggtctat atccgcaatt
    11641 ttcttttcgc gtctttgcag atagggcata ccatccttaa aaaccagttc ctgcccgtcg
    11701 ggaatagtaa caatgccatt ggccgtagag gataaatcta cgttaccgcc ataaatagga
    11761 cttccaggca tgtagtccga catcacattc gcttcccctt cattcgccaa tgaaaaacct
    11821 cccgtatttc ctacggacaa gccaaccgcc catcctttag catccctacc agaactgttt
    11881 ttttccggaa gatgcagttt gtcccggcct gacggacgat agcggtcttc ccttgtctcc
    11941 ggttcctcgg tctgcattgt agtttcatgg tccgtatctt ccactaccgg ttcttccgcc
    12001 tgctgtccaa taccgacaac ctcatctgca gtttcaaccg gcagcatttc ctcctgctgt
    12061 tcttcgccaa ccgatattct gatatgttgt gcaaccaaag ggtgacttgc ctccttattg
    12121 ggcgccgatg catttccatg tgcccgataa gcaggctcta tggaattagt ccgtatggca
    12181 ggtactgtct gttccggcaa gacgtccgga gccacagcca aagcgggcac tgacgtatgc
    12241 cgcatttcat tccctaccgg actctgcaac agccacagac tgacggacga aaccgccacc
    12301 agcaacacag ctgccgcggc caccgcccag cgacggaaag gtatcatcct atgcggtccg
    12361 gttatcggag ctccggaaac ggacaattcc ttctccaacc gctcccatcc ggcaaccggc
    12421 agcggttcgg aatagtcttc cagcttgtcc tttatctttt tcaaccacaa ttcatcttcc
    12481 atacgttcct tcatttaatc atttcttttc atccactcac gtacttttgc cgctaaagtc
    12541 gctttagcac gcgtcaactg cgaggcagag gatttttcat taattcccaa tagtcgagca
    12601 atctccttat gggatttctc ttcaaaaata tataagttga atacggtacg atagccggca
    12661 ggcaattcac tgataaactg cattagtacc ttttgaggaa tgacatctat tgacgaacct
    12721 tccggttcct cataagcttc aggtgcattc tccaaggccg atgactgatt catcacatca
    12781 tttttccgca aatactgcaa caccgtattc accattacgc gttccatcca tgcccgcaga
    12841 gaaccctctc cccgccaagt gaacttatcg aaagaatcaa aaagtttcag aaaaccgtca
    12901 tgcatcaggt cttgggcagt ctcccggtca cctgcataac gaaggcatac gctgagcatg
    12961 cgtcccgcat agcgctcata cagttctttg cgggcaagat tgtctccttg cctacagcgt
    13021 tctgccaatt cctgttcttc cattctctct tttaacacgt gtttacccta taaatgcaat
    13081 cggcgcaaaa atactgcatc aggcagagaa gaaaatcata ctttcatttc tttaacagta
    13141 tactacgcag tatttagctt ttcaccgcat tttctgaata caaaaataag ttttaaacag
    13201 aaaagagcta aaacctacca cttatgaaga aactgagaat gacattggca acatccatgc
    13261 ttttattcct gactgccatt gtattgcaat catgcctgga cgattgggat gacaaatatg
    13321 acactttgtt cgccgtaggt acggtaaagg tcatcgaagg aaaagactac tatttctcac
    13381 tggacgaagg cagtaaacta tatcccagtg acacaaccta tgttcacgac tatgccgtaa
    13441 cagacggcca gagggctttc atctacttcc gcgaactgga agagaaactt ccaggctacg
    13501 aatacaatgc ccaaataaag cacatcgaaa atattctgac caaagacatc tactccatgc
    13561 ctgccgaaaa ggcggacagt atcggagacg acaacatcaa cgccacggat ttatggatta
    13621 cgggtgagta tctgaacatc aagtatcaat tctaccacag taacaacgaa gataagaagc
    13681 acatgctgaa cctggtcatc aacgaagcat ccaccggcga gaacgacaaa ccggattacg
    13741 tcaatctcga attccgccac aatgcctaca atgacagcca gctcacactg ggcaccggac
    13801 tggcctcctt caagctggac aatatagcgg aacagctgaa agagaaaaaa ggactgaaca
    13861 tccgcgtcaa aagtctatat gacggtgaac ggttcatgac catagacatt aaaaaagaaa
    13921 acaactaaat ctcctgaaaa cacatttttc aacatctcaa tgagaagcgg agtaacattt
    13981 caatatgttg ctccgctttg tttttccata acttatcaga attcattgtt caagcaagtc
    14041 agcctcaacg aagcgttgaa cgcttcggca gacaatcgcg tcctgacctg tacctgcacg
    14101 ctgctcttcg gctggacatc aaaataattg tcgctatata cactttcatt gtcagcaacg
    14161 gacaagcata cggcacgggc aaacttgtct gttgataccg tcacttcata tccgccttca
    14221 atggaacgga cttcggtctg caaatccact ttcggataat tcatattctt ctgcttgtcc
    14281 agacagtagt tgttatggta caccctgccc gatttgtccg tatagtctac gcggacatat
    14341 accgttcctc tatctgcccc ctccagcagc ttggcaagcg gtgcggaaaa acagacacgg
    14401 ctgtcattac cggaaatgcc gacagatttg tcccagtgat aaaccacagt gccgtcgaac
    14461 cggcagacct ggagctgcag ccggccggaa gtattctcca agcggtcgga cactgcatat
    14521 actttcaaat catccccctc cactaccgga gaaatcagga tgtcatcata gaccttgcga
    14581 gtataatagt gctgcgcctt ccagcgtccg taatagtcac ggctcgccca ggaagctacg
    14641 ggccaacagt cgttgtgctg ccagaaaagc gtccccatat tatacggcat ctggcggcgg
    14701 tgcgactcga tggccgtctt gatggcatct ccctgcagca catggttcat ataaaggaat
    14761 gcccggaaat cacgcggctt tttatattca ttcaataggt aagtctcaat cagcccgttg
    14821 gcatggtcgc caccacgctg atgggacatc atcacctcgg aacgtatatc ccagtcttcg
    14881 gggtaaggag catagcgctt gacggagtcg aactctggaa aagactgaaa gccgtactcg
    14941 ctgaaaaagc gggatttctc gctgtcataa tcggaaatgg gtgctttacc atgccagaca
    15001 ctccaatagt gacggtcccc gtcagtagta ccggacatct ctccctcgaa tgcgaacgga
    15061 gaagaaggcc aatagaaggt tccgggtgca tactccctga ccaccccggg taaggtgaca
    15121 tgatactgct gccggtactg tgcccaaatc ttgtcggcat attccttgtt ctgccgttct
    15181 atctcgcact tccagcccca gcccagccag gcatcctggc attcattgtt tccacaccac
    15241 aaagcaatgc aggcatgatt gcgcaaacgt ttcacattgt ccaccgcctc ctgatggata
    15301 ttatcgagca gggcgccttc tgccggatac atgctgcagg caaacataaa gtcctgccaa
    15361 atcataattc catgctcatc acacaaatca tagaagacat cgttctcata gatacctccg
    15421 ccccagacac gcaacatatt catgtttaca ccggcggcat cgagaatcgt ccttttataa
    15481 ttctcgggag tgacgcgcgg caggaagtta tccgaaggga tgtaattggc tcctttggca
    15541 aaaaccggac gcccgttcag ctctatatag aaagtatgcc cgtccttatc cggctgatgc
    15601 accaccttca aagagcgtat gcccaccctt tcggttttag agtccaacaa ttccccgcct
    15661 gcaatgatat ccgtacggaa acggtaaagg aaaggctccc ccagtccatt actccaccac
    15721 agcttcggct tgtgaaggac gaaatcaacg gtcacccgat tggtgcctcg cttcaaatcc
    15781 gcttgccact cgccaagcac tcttccggta gcctcgtctg ttatcgtgac cagcactccg
    15841 tccatatcct tatcggcatc cagctccaca tgtccggcaa tcacggccct gcctgcaccg
    15901 acttccttct gctcgataaa cacatcgttg attctcaaat cgctccaagc cctgatatac
    15961 accggacgcc agatgccgga ggtaaccaga cgtgggcccc agtcccagcc ataatgataa
    16021 cccgccttac gggcaaaaat gcttatcttc ttgttgaaca agcctccgtt ttcagactgg
    16081 tcattggatg ccggatactg gtaaggaagt gcatcccatt tggggacgtc tatctttacc
    16141 ggcgaatgga agtacacctt caatatatta ttctcctccc tgatgtactg cctaacgggg
    16201 atagaccagc ggcgaaacat attgtc
//
