LOCUS       c00239_gnlPro..        15595 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JFAGBGHC_239.
ACCESSION   c00239_gnlPro..
VERSION     c00239_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 17:38:36
            Original ID  :: gnl|Prokka|JFAGBGHC_239
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15595
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15595
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[958:6193]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      959..6193
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15595
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15595
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(3..827)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg239_1"
                     /sec_met_domain="Epimerase (E-value: 8.4e-53, bitscore:
                     169.1, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGKILVTGGTGYIGSHTVVELQNAGYEVVIIDNLSNSSADVVDN
                     IEKVSGIRPAFEELDCLDYAGLDAVFTKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEIV
                     RDTVASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVVAIHRILENKQKEKVEVFNIGTGRGLSV"
     CDS             complement(959..1543)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_2"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.3e-64, bitscore:
                     207.3, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETALGMSAA
                     VAFVLTIATIVTFLIQKYVLDAFDLGYLQTITFILVIAALVQMVEIILKKVSPSLYQAL
                     GVFLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTALGFGLALTLFAGLREQMSLVS
                     VPKGMQGTPIALITAGLLAMAFMGFSGVVKI"
     CDS             complement(1631..2197)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_3"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.1e-70, bitscore:
                     227.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISAIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPALYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNPVASLFDGLGMGLGFTIALTLLGAVREFLGTGKIFNLSILPEEYGML
                     VFVLAPGAFIALGYLIALINSMKKN"
     CDS             complement(2232..2867)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_4"
                     /sec_met_domain="FMN_bind (E-value: 2.5e-24, bitscore:
                     75.7, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKEPIAQANAKTLSDAVSAVVPG
                     FDNDPIAEKKMQEVNGVQYSVYPATKGGEYIGAAVEAVAMGFGGELKVLVGFDAEGKII
                     DYSLLSHVETPGLGSKAADWFKKGNKGDITGMNPGEAALTVSKDGGKVDAITASTITSR
                     AFLNAVNAAYAAYAGQETADGTTGATQKNVEQPADSAAPEAVDTLSAK"
     CDS             complement(2894..3886)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_5"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 2.4e-119,
                     bitscore: 387.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLIVSLSPHVHGGDSVKKNMYGVLIALIPAFLVSLYFFGLGAL
                     IVTATSVAACLFFEWAIGKFLMKKETTTITDGSAIITGVLLAFNLPSNLPIWIIILGAL
                     FAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPAVGQLTAYTDATTAATPLA
                     IMKGVINGAPGMSLSDLPGAFDLLIGNNGGCLGEVSALALLLGLFYMLWKKIITWHIPV
                     SILVTVFVFSGIMYLVNPELYVSPVVQLLSGGLMLGAVFMATDYVTSPMSHKGMLIYGV
                     CIGLLTVIIRLFGAYPEGMSFAILIMNAFTPLINTYVKPKRFGEVAKKK"
     CDS             complement(3893..5230)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_6"
                     /sec_met_domain="Fer4_10 (E-value: 2.2e-09, bitscore: 27.3,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4.5e-16, bitscore: 48.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.3e-49, bitscore:
                     158.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 5.4e-30, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.2e-05, bitscore: 14.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIIKAEIPAKAAILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEPGGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEESIDRSETLVKECSLTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPAFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVQYPQGGEKQLIDAVISRQVAAGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSLAKPSNFLARIGTPMKQLIEACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNEKEAKRGEVQPCIRCAKCVGACPMGLEPYLLATVSAHGDFERV
                     EKEDIMSCIECGSCQFTCPSNRPMLDYIRLGKGKVGAMIRARQAKK"
     CDS             complement(5291..6193)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 37.6; E-value:
                     8.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_7"
                     /sec_met_domain="Fer4_7 (E-value: 1.9e-12, bitscore: 37.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.1e-09, bitscore: 27.9,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 5.8e-09, bitscore: 25.8,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 6e-09, bitscore: 25.8,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.3e-11, bitscore: 34.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.8e-06, bitscore: 16.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVILIAVISLGVIALVSAAILYVASKKFAVYEDPRIAQVAEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKLCPVGGQPVMTKIAEILGLDAAAAEPMVAVV
                     RCNGTCANRPRVNQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACAKACPKSIIEIRPQGKKSRRVYVQCVNKDKGAVARKACTVACI
                     GCGKCVKVCPFEAITLENNLAYIDPNKCKSCRKCEEACPQNTIIALNFPPRKPKADDAA
                     PQVKVAAPKAEVETPKAEV"
     CDS             complement(6231..6650)
                     /locus_tag="ctg239_8"
                     /transl_table=11
                     /translation="MANTIKHQGIVENINGSHLQVRIIQTSACASCSVKGHCTSADTKE
                     KLVDVADADAASYQPGDRVWVTGELSMGVMAVLFAFIFPFLILIISLFVFMAIWNDELR
                     SALCSLALLVPYYYILWLNKSRMGKKFSFSVRPMN"
     CDS             complement(6881..8281)
                     /locus_tag="ctg239_9"
                     /transl_table=11
                     /translation="MISSSVMAQNTLDTASKNSGQETTAKADTLPDIMKEYMILKLKPE
                     GMGYKLDTVSILYERYIGVLDYLNDPTTPERYIPSNPNYYRLFLPLTYYYAPMRRLSKV
                     DWHFQVPDTVPALTREMLPFDTLSFTSKDRANKLVDRTLLNTYVDCPNLVVMTEKEVMK
                     GKIFKDNIEKEVSSKPSVVKLFAQENMVGVKEEADVIIHKPNWWVTGGNGSLQITQNYI
                     SDNWYKGGESTNAVLANLQLFANYNDREKVQWENLLDAKLGFSSAPSDEFHNYLVSTDQ
                     LRLYSKLGIQAASKWYYTITTEFKTQFCNGYKANSEELVSAFFAPADWSSSIGMDYKLK
                     KQKFSLSVFMAPLTYMLRYVGNKGVNEVSFGLDEGKCVKHNFGSQIQPTLSWTIIPSIT
                     LDSRLDFQTSYEWTRIEWENTVNFVLNRYLSTKLYVHARYDDSAKPTEGDSYFQVKELL
                     SFGINYKW"
     CDS             complement(8353..8559)
                     /locus_tag="ctg239_10"
                     /transl_table=11
                     /translation="MPRAYTACRSGCALLPSVHVELKKRKIIKKRGSRESFDETIIKKY
                     DFIEESPSCLFLMAFLCFLNILS"
     CDS             8591..10210
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg239_11"
                     /sec_met_domain="GATase (E-value: 8.4e-55, bitscore: 175.4,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGETKYIFVTGGVASSLGKGIISSSIGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLGIQTTKANNITTGRIYKSVIDKE
                     RRGDYLGKTIQVIPHITDEIKRNVKLLGNKYKFDFVITEIGGTVGDIESLPYLESIRQL
                     KWELGKDALCVHLTYVPYLAAAGELKTKPTQHSVKELQSAGIQPDVLVLRTEHELSTTL
                     RKKVALFCNVDENAVVQSIDAPTIYEVPILMQSQGLDVTILKKMGLPVGDTPGLGPWRA
                     FLERRHKAEETAPLHIALVGKYDLQDAYKSIREALSQAGTYNDRKVSVDFVNSEKLTDE
                     NVTEALKGMAGVLIGPGFGERGVAGKFVAIKYARTHDIPTFGICLGMQCIAIEFARNVL
                     GYADANSREMDEKTPHNVIDIMEEQKSITNMGGTMRLGAYECVLQKGSKAYEAYGTEHI
                     QERHRHRYEFNNSFKDAYEAAGMKCVGINPESDLVEIVEIPALKWFVGTQFHPEYSSTV
                     LHPHPLFVAFVKAAIENENEKK"
     CDS             10242..12095
                     /locus_tag="ctg239_12"
                     /transl_table=11
                     /translation="MDKNTITGLVLIAILLVGFSFLSRPSQEQLEAQQRYYDSIAQVQQ
                     READLKAKAEAALANESGAEASVDSTALFFDARQGTNSQVTIQNNLAEITVDTKGGRIA
                     SATLKEYMGQDKTTPVTLFSGNDASMNFLFYNKKETIQTEDYYFTAVNRTDSTVTMRLS
                     ADSNSYIDFTYRMHNDTYLIDFTIQAVNMEGKLATTNNYVDIEWSQRARQIEKGYTYEN
                     RLAELTYKITGEGTDYLSANKNDEKEVPERLDWIAFKNQFFSSVFLADADFEKTKLSSK
                     METQGSGYIKDYSAEMSTKFDPAGKEPTQLFFYFGPNHYKTLTALDKGRDEKWELNRLV
                     YLGWPLIRWINKWFTINIFDWLSSWGLSMGIVLLFMTLIVKAVVFPATWKTYMSSAKMR
                     VLKPKIDEINKKYPKQEDAMKKQQEVMGLYSQYGVSPMGGCLPMLIQFPILMALFMFVP
                     SAIELRQQSFLWADDLSTYDAFINFPFHIPFLGSHLSLFCLLMTVTNILNTKYMMQQQD
                     TGANPQMAAMKWMSYLMPIMFLFILNDYPSGLNYYYFISTLVSVVTTLIMRKTTNEEAL
                     LAQLEANKKDPKKMKKTGFAARLEAMQKQQEQMMKEKQNKK"
     CDS             12198..13529
                     /locus_tag="ctg239_13"
                     /transl_table=11
                     /translation="MQTKYTYKQIWLIAYPILISLLMEQMIGMTDTAFLGRVGEVELGA
                     SAIAGVFYMVIFMVAFGFSIGAQILIARRNGEQQYKEIGDLFYQGIYFQVGMATVMFLL
                     SYCFSPIILKRIVASEHIYEAATSYLHWRVFGAFFSFSAVMFRAFFLGTTQTKTLTLNS
                     IVMVLSNVVFNYILIFGKFGFPALGIAGAAIGSSLAELVSLLFFILYTRSRIDCCKYGL
                     DRIPKFRLDVLKRMLNVSFWTMIQNFFSLSTWFLFFLYVEHLGERSLAVTNIVRNVSGI
                     LFMVLMAFASTCGSLVSNLIGAGHSDCVAGTIRQHVRIAYVFVLPLALLFAVFPKLILG
                     IYTDIPDLQDAAVHSLWVMCSTYLFLVPANVYFQAVSGTGNTRTAWGLEMATLVIYTAY
                     ITYIILILQLDVAICWTSEMVYSSFILIFCWLYIKRGNWQGRKI"
     CDS             13591..15594
                     /locus_tag="ctg239_14"
                     /transl_table=11
                     /translation="MSAAMTLASCGGTKDAGQQQDAAALIQRSDIKIEGKRMTPEALWA
                     MGRIGSVAVSPDEKQIAYTVSYYSVPQNKSNSEVFVMNADGSGNTQITHDAWQEGQPTW
                     FKDGKKLAFLCNESGSSQVWEMNPDGSGRKQLTQYEGDIEGFSFSPDGKKLLFIAQVKT
                     VKSTADKHPDLPKATGIIVTDLMYKHWDEWVTTAPHPFVADFDGNAISNVTDILEGEPY
                     ESPMKPWGGIEQLAWSPSSDKVAYTCRKKTGLAYAISTNSDIYIYDLASKETKNITEEN
                     KGYDTNPQYSPDGKYIAWQSMERDGYEADLNRLFIMNLETGEKRFVSKAFESNVDAFLW
                     NKDSQSIYFIGVWHGETQIYNIDLAGNDKLTQLTDGMHDYASLALCGDKIIAKRHSMSM
                     GDEIYAVNSARNGDAFAEAVQLTTENKQIYDQLEMGKVEARWMKTTDGKQMLTWVIYPP
                     QFDPNKKYPTLLFCEGGPQSPVSQFWSYRWNFQIMAANDYIIVAPNRRGLPGFGVEWNE
                     AISGDYGGQCMKDYFTAIDEMAKEPFVDKDRLGCVGASFGGFSVYWLAGHHDKRFKAFI
                     AHDGIFNMEMQYLETEEKWFANWDMGGAYWEKNNATAQRTFANSPHLFVDKWDTPILCI
                     HGEKDFRILANQAMAAFDAAVMRGVPAELLIYP"
ORIGIN
        1 aatacggaaa gtccacgacc tgtaccgata ttgaatactt ccactttttc cttctgcttg
       61 ttctccaaga tacggtggat agccactacg tgtgctttgg ccaaatcgac tacattgatg
      121 aagtcgcgga tacaagaacc gtcgggagta tcataatcgt caccaaacac gctcagtttc
      181 tcacggatgc cgatagcggt ctgggtaaga taaggaatca agttctgcgg tacaccgtta
      241 ggcaactctc ccaacaatgc tgtggggtgt gcacctatcg ggttgaagta acgcaacaag
      301 atggcgttta tcggagcacc ggaagcaacc gtatcacgta caatctcttc attgatttgc
      361 ttcgtgtttc catacggaga ctcagctttc ttaataggtg ccttttccgt taccggaagt
      421 tcgtccggct ggccgtaaac tgtgcaggaa gaagagaata cgataccttc cactccatgc
      481 ttcggcatca attccagcag gtttatcagt gaaaccaggt tattacgata gtaaagcaat
      541 ggtttctgga cagattcacc cacagccttg ctggccgcaa agtgaatgat ggctttaatg
      601 cctttatatt tggtaaacac agcgtcaaga ccggcataat ccaagcaatc caattcctcg
      661 aatgcagggc ggatgcccga taccttctct atgttatcta caacatctgc gctggagttt
      721 gacaaattat caataataac aacttcataa cctgcgtttt gaagttccac caccgtgtga
      781 gaaccaatat aaccggttcc acccgtaact aagattttcc ctttcatatt aaatatagat
      841 aatttagctt ttaggttatc aatacgccac aaatgtaagg aaataaatta ataaaaacag
      901 aaaaaggggg ataaatttta gtttatcccc cttccacttt atttccggtt tttcttcttt
      961 aaatcttcac aacccccgaa aagcccatga atgccattgc cagcagtccg gcagtaatca
     1021 aagctatcgg agtaccctgc atacctttcg gtacactaac caggctcatt tgctcgcgca
     1081 ggcctgcaaa cagtgtcagt gccaagccga aaccaagtgc cgtggagaat gcataaacca
     1141 ctcccgtcag caaatcataa tctttttgga taacaaggat agccacaccg agaatacagc
     1201 agttggtagt aatcaacggc aggaacacgc ccaaggcttg atacagagaa ggagaaactt
     1261 tcttcaggat aatctctacc atctgcacca atgcggcaat caccaggata aaggtaatag
     1321 tctgcaaata gcccaaatca aaagcgtcga gcacatactt ctgaataagg aatgtcacga
     1381 tagtggcgat ggtgagcacg aatgccaccg ccgccgacat gcccaatgca gtctccactt
     1441 tcttggaaac tcccaagaac gggcaaattc ccaagaattg cgacaatacg atgttgttta
     1501 caaagattgc cgagataaat atcaatatat attccataat cattaaatta agaattaaaa
     1561 actaaaaatt aaaagcccgg cagcctaccg ccgatacgtt ctcaattttt tcatttttaa
     1621 tttttcatta ttaattcttc ttcatactgt tgattaaagc aatgagatag cccaatgcga
     1681 tgaatgcacc cggagcaagg acaaatacca acatgccgta ttcttcagga aggatactca
     1741 agttgaatat cttgccggtt cccaggaact cacgcacggc acccagtaat gtcagtgcaa
     1801 tggtaaagcc caagcccatg cccagaccgt cgaacaagga agccaccgga ttgtttttgg
     1861 cagcaaatgc ctcggcacgt cccaatacga tacagtttac aacaatcagc ggaatgaaca
     1921 ggcccagtgt ggcgtacaat gcaggaacgt aagcttgcat tatcatctgc aacagtgtca
     1981 caaatgatgc tatgactaca atgaatgaag ggatacgcac catatcggga atcagattct
     2041 tgatggcaga aatcaccaca ttggaacata tcagcacgaa cattgtagcc agtcccatac
     2101 ccataccgtt aatggcagag gaagtggtac ccagtgtagg acacataccc agcaggagta
     2161 caaacgtagg attctctttg ataatcccgt tcatcataac tttaaaatta ttcatatctt
     2221 ctactccttt ctcatttagc gctgagtgta tctacagctt cgggagctgc ggaatcagca
     2281 ggttgttcaa cattcttttg agtagcgccg gtagtgccgt cggcagtttc ctgaccggca
     2341 taggcagcat aagccgcatt cactgcattc aaaaaagcac gtgaggtgat ggtagacgct
     2401 gtaatggcat ctactttacc accgtccttg ctcactgtca atgcagcttc acccggattc
     2461 atgccggtga tgtcaccttt attgcctttc ttgaaccagt cggcagcctt ggaacccaac
     2521 cccggagttt ccacatgcga caacaaggag tagtcgatga ttttgccttc agcatcgaaa
     2581 ccgaccaaca ctttcagctc accgccaaaa cccatggcaa cagcttccac agcagctccg
     2641 atatattctc cgcctttggt ggcaggatat acagaatact gtactccgtt tacttcctgc
     2701 atcttcttct cggcgatggg gtcattgtcg aagcccggaa ccaccgcact tacggcatcg
     2761 ctcaaggtct ttgcattggc ctgcgcaatg ggctccttcg tcaattcgtt tacataagcc
     2821 agcaacgcta cggagattgc ggtaacgccc gtaagtacca gcaacatatt cttcaaggat
     2881 gattctaact ttttcatttc ttcttcgcta cctccccaaa gcgtttaggt ttaacatagg
     2941 tgttgatgag cggagtgaac gcattcataa tcagaatggc aaacgacata ccctccggat
     3001 atgcaccgaa cagacggatg atgacagtca gcaggccgat gcaaacacca taaatcagca
     3061 tacctttgtg gctcatcgga gaagtcacgt agtccgtagc cataaagaca gcacccagca
     3121 tcagaccacc ggacaacaac tgtacgaccg gggatacata aagttccgga ttgaccagat
     3181 acatgatacc ggagaacacg aataccgtca ccagaataga taccggaatg tgccaggtga
     3241 tgattttctt ccacaacatg tagaacaaac caagcagcag cgccaaggca ctcacctcac
     3301 cgagacatcc tccattatta cctatcagaa ggtcgaaagc tcccggaagg tcgctcaggg
     3361 acatgcccgg agcaccattg atgacacctt tcataatagc cagcggcgta gcagccgtcg
     3421 tggcatccgt ataggctgtc aactggccta cagccggcca tgtcgtcatc tgcacgggga
     3481 atgaaagcaa caggaataca cgtcctgcca gtgcagggtt aaagggattg caacccaaac
     3541 ctccgaagga catcttgcct accccgatgg caaacaaggc accaaggatg ataatccaga
     3601 tgggcaggtt ggaaggcagg ttaaaggcca gcaacacacc ggtaatgatg gcagagccgt
     3661 cggtgatggt tgtggtctct tttttcatga ggaatttgcc gatggcccat tcaaagaaca
     3721 agcaggctgc tacggaagtg gccgtaacaa tcagcgcacc cagtccgaaa aagtaaagcg
     3781 aaacgaggaa tgccggaatc aatgcgataa gcacaccgta catattcttc ttcacgctgt
     3841 caccgccgtg aacgtggggc gaaagggata cgattaattt attcatactt cgttattttt
     3901 tagcttgacg tgcacggatc atcgctccta ccttaccctt acccaagcgg atataatcca
     3961 gcatcggacg gttggaagga caagtaaact ggcatgaacc gcattctata cacgacataa
     4021 tgtcttcttt ctctactctt tcaaaatctc cgtgggccga aacggtagcc agcagatacg
     4081 gctccaaccc catcgggcag gctcccacgc acttggcaca acggatacaa ggctgtactt
     4141 cgccgcgctt ggcttccttc tcgttcataa tcagaatacc ggagcttcct ttggctgtcg
     4201 gtacatccgt atttaccaga gctttaccca tcatcgggcc accgccgata atcttgcccg
     4261 tatcttcggg cagaccgccg caagcttcaa tcagctgctt catcggcgta ccgatacgtg
     4321 ccaggaaatt ggacggcttt gccaacgact taccagtcac ggtaatgaca cgttcaaaca
     4381 gaggtttgtt cttctgtacg gcctggtaaa cggcaaatgc ggtacccaca ttctgcacca
     4441 cagctcccgt ggagataggc agcgcaccgg ctgcaacctg gcgactgatg actgcatcaa
     4501 tcaactgctt ttcaccaccc tgcggatatt gtaccttcaa gggtaccacc tcgatacctg
     4561 cataactgga agcgactttc gtcatcagct ggatggcatc gggcttgttg ttctcaatgc
     4621 caatgaatgc cttgttcacc tttaccgctt tcatcagaat ggatacacct accataattt
     4681 cttccgcatg ttccagcatc agctgatggt cggcagtcag atacggttcg cactctacgg
     4741 cgttgatgat gacacactct gccttgaatg caggaggagg acacaacttg acctgcgtag
     4801 ggaagcatgc accgcccaga cctacgatac cggcatcagc gattttcttc acgatttcct
     4861 cggaggtcag actgcattcc ttcaccaacg tttcggaacg gtcaatggat tcttcccatt
     4921 catccccttc tacgtcaatg aatatagcag gcttggcgta accgctggca tcgacaatcg
     4981 tgtcaatctt agcgactttc ccgctgacag acgaatgaat ggctgctgat acaaaaccgc
     5041 cgggctcggc aatctttgta cccactttca caacatcacc tttggcaacg ataggcttgg
     5101 caggagcacc gatgtgctgt cccagcaaga tagcggcctt ggccggaatc tctgccttga
     5161 tgataggctg atgtgctgaa agtttatttt cgtgtggatg gactccacca attgaaaatg
     5221 tcttcaacat acaattctgt atttttagtc gtttatttac tttattaatt catacctcaa
     5281 cttgggaagt ctaaacctct gctttgggag tctcaacctc agctttagga gctgcaacct
     5341 ttacttgggg agctgcatcg tcagccttcg gtttgcgcgg cgggaagttg agggcaatga
     5401 ttgtgttttg cggacaagct tcctcgcact tgcgacagga tttgcactta ttggggtcaa
     5461 tgtaagccag attgttttcc agcgtgatag cctcgaacgg acaaaccttc acacacttgc
     5521 cgcaaccgat acatgccacg gtacaagcct tgcgtgctac ggcccccttg tccttgttta
     5581 cacactgtac gtaaacacga cgtgatttct tgccttgagg acggatttca atgatagatt
     5641 tcggacaagc cttggcacaa gctccacaag ccgtacactt ttcctcatcc acttcgggaa
     5701 gtccggtctc cggattcatg tggatagcat cgaactggca ggcagccaca cagtcgccgc
     5761 atcccagaca gccataacta caacccgttt caccaccata gagagaagcc gcaatggcac
     5821 aactcttggc gccatcgtat tggttcacac gaggacggtt ggcacaagtt ccattacatc
     5881 tcaccaccgc aaccataggt tcggcagcag cggcatccaa gcccagaatc tcggcaatct
     5941 ttgtcatgac gggctgtcca cccaccggac aaagtttacc atccagcgaa cctgccttta
     6001 cgcaagcatc tgcaaatccg ctacaaccgg ggtaaccaca tccaccgcaa tttgcctggg
     6061 gaagcacctc tgctacctgg gcaatccgcg gatcttcata cacggcgaat ttcttggaag
     6121 ccacgtaaag aatagcggcc gataccagcg ctataactcc caatgaaatc actgcaatca
     6181 gaattacatt cataaattag ttgtttatta attatttgtt ttattattag ttagttcatc
     6241 ggtcgtacgg agaatgagaa cttcttaccc atccgcgact tgttcagcca caatatataa
     6301 taataaggta caagaagtgc tagcgaacaa agcgcggaac gcagctcgtc attccagata
     6361 gccataaaga caaatagtga gattatcaga ataaggaaag gaaatataaa ggcaaacaga
     6421 actgccatca ctcccattga aagttcgccc gtcacccata cacggtcgcc gggctggtag
     6481 gatgcggcat cggcatcggc cacatcgaca agtttctctt tcgtatccgc agaggtacaa
     6541 tgtcccttga cactacacga agcgcacgct gaagtctgga tgattctcac ttggagatga
     6601 gaaccgttta tgttttccac aataccttga tgttttatag tattcgccat tttgcaaagt
     6661 gtgcattaca aatcgcggca aatttacgca ttatttgtga actgcaaacc tttcctatgc
     6721 attttctgtg ttcgtaaacg tgctttttct atgtttttat gttttttcac ctgccacaga
     6781 ctacaaaaag acaaaaaaca gacggtctgt caagggaaaa cagaccgtct gactaactaa
     6841 aacagataat ctgttcactc cgaacagacc atttgtttat ttaccattta taattgatac
     6901 cgaaactgag cagttctttt acctgaaaat agctgtcccc ttccgtcggc ttggcactgt
     6961 cgtcatagcg ggcgtgcaca tagagcttgg tggaaagata gcggttcagc acaaagttca
     7021 ccgtgttttc ccattcaata cgtgtccact cataactggt ctggaagtcc aagcgggaat
     7081 ccagcgtgat ggaaggaatg atggtccatg aaagtgtagg ctgtatctgc gaaccgaagt
     7141 tatgcttcac gcatttgccc tcatcaagac cgaaactcac ttcattcacc cccttatttc
     7201 ctacatagcg cagcatgtac gtcagcggag ccatgaaaac ggacaagctg aatttctgct
     7261 tcttcaactt gtagtccata ccgatactgc tcgaccagtc cgccggagca aagaaagccg
     7321 aaaccagctc ttcactgttg gccttgtagc cattgcagaa ctgggtctta aactcagtcg
     7381 tgatggtata ataccacttg gacgcagctt gaatacccag tttactgtac agccggagtt
     7441 ggtcggtact taccagatag ttatgaaact cgtcggaagg tgcggagctg aagcccagct
     7501 tggcatcgag cagattttcc cactgcacct tttcacggtc attatagttg gcaaacaatt
     7561 gcaggttggc aagcacggcg ttagtgctct cacctccctt gtaccagttg tcggagatat
     7621 agttctgggt aatctgcaat gaaccgtttc cacccgtcac ccaccagttg ggcttgtgga
     7681 taatcacgtc ggcttcctcc ttcactccca ccatattctc ttgtgcaaac agtttcacga
     7741 cggacggctt ggaagaaacc tccttctcta tattatcctt gaatatcttc cctttcatca
     7801 cctccttctc ggtcattaca accagattgg gacaatctac atacgtgttc agcagcgtac
     7861 ggtccaccag tttgttggct cggtcctttg aggtgaaact cagtgtgtcg aacggcaaca
     7921 tctcgcgcgt cagggcaggc accgtatcag gcacctggaa atgccagtcc accttggaaa
     7981 ggcgtctcat gggggcataa taataggtaa ggggaaggaa caacctatag tagttcggat
     8041 tggaaggtat ataacgctcc ggagtcgtgg ggtcattcaa ataatccagc actccgatat
     8101 acctttcata taatatggaa acagtatcca gcttgtaacc cataccttcc ggtttcaatt
     8161 tcagaatcat gtattctttc attatatccg gcaaggtgtc ggctttggca gttgtttcct
     8221 gtccactgtt cttcgaggcg gtatccagcg tattctgtgc catcaccgac gaagaaatca
     8281 tcgtagcaat taaccaaaat gcaatgtgtc tattcttcat aatgccctaa agtctatgtt
     8341 tcgagcgcaa atttagctta aaatgtttag aaaacataga aaagccataa gaaaaaggca
     8401 agaaggactt tcttcgatga aatcgtattt tttaataatt gtttcatcga aactttctct
     8461 acttcctctt ttttttataa ttttgcgctt tttaagttct acgtgtactg acgggagcag
     8521 tgcgcaccct gaacgacaag ccgtataggc tcttggcatt agattaaaca attaataaaa
     8581 taatatagtt gtgggagaaa caaagtatat tttcgtcacc ggtggtgttg cctcttcatt
     8641 aggtaaaggt atcatctcat cctccatcgg taaattgctg caagcaagag gttacaaggt
     8701 aaccatccag aagtttgacc cgtacatcaa catcgacccg ggtacactga acccttatga
     8761 acacggcgaa tgctacgtta ccgtggatgg ccacgaagcc gacctcgatt tgggccatta
     8821 cgaacgcttc ctgggcatcc agaccaccaa ggccaacaat atcacgaccg gacgcatcta
     8881 caaaagcgtc atcgacaaag agcgccgggg tgactatctg ggaaagacaa ttcaggttat
     8941 tccccatatt acagacgaaa tcaagcgtaa tgtaaaactg ctgggaaaca aatacaaatt
     9001 cgactttgtt attaccgaga ttggcggtac agtgggtgac atcgagtctc tgccctatct
     9061 ggaaagcatc cgtcagctga agtgggaact gggaaaagac gccttgtgcg tacaccttac
     9121 ttatgtcccc tacctggcag ctgccggtga actgaagacc aagcccaccc agcactccgt
     9181 aaaggaactg caaagtgccg gtatccaacc cgatgtcctc gtactgcgta cggagcacga
     9241 gttgagcact accctgcgca agaaggtggc tctgttctgc aatgtggacg agaatgccgt
     9301 ggtgcagagc atcgacgcgc ctaccatcta cgaggtgccc atcttgatgc agagccaagg
     9361 actggacgtt accattttga agaaaatggg acttcccgtc ggtgatactc cgggactggg
     9421 accgtggcgc gctttcctcg aacgccgtca caaagccgaa gagactgccc cgctgcacat
     9481 cgcattggtg ggcaaatatg acttgcagga tgcctacaag tccatccgcg aggccctttc
     9541 acaagcagga acctacaatg accgcaaggt gtcggtagac ttcgtgaaca gtgaaaagct
     9601 gacggacgag aatgtgacag aagccttgaa aggtatggca ggcgtactta tcggtccggg
     9661 cttcggcgaa cgcggcgttg ccggcaagtt cgtagccatc aaatatgcgc gtacgcacga
     9721 catccccacc ttcggtatct gtctgggtat gcagtgtatc gccatcgaat ttgcccgtaa
     9781 cgtactgggt tatgccgatg ccaactcacg cgagatggac gaaaagacac cgcacaatgt
     9841 catcgacatc atggaagagc agaagtccat caccaatatg ggtggaacca tgcgtctggg
     9901 tgcctacgaa tgtgttctgc agaaaggcag caaggcatac gaggcatacg gtaccgagca
     9961 tatccaggaa cgtcaccgtc accgctacga attcaacaac agcttcaagg atgcctacga
    10021 agcagcaggt atgaagtgtg tgggtataaa ccccgaatcg gacttggtgg aaattgttga
    10081 gattcccgca ttgaagtggt ttgtcggtac ccagttccat cccgaataca gcagtacggt
    10141 attgcatccg cacccactgt tcgtagcatt cgtgaaggcc gccatcgaaa atgaaaacga
    10201 aaagaaataa tttgtaataa gtaatttgta atcaacaaag aatggataaa aataccatca
    10261 caggtcttgt tctgatagcg atattgttag taggtttcag ctttctgagc cgtcccagcc
    10321 aggagcagtt ggaagcacag caacgttact acgactccat agcccaggtg caacagcgcg
    10381 aagccgactt gaaagccaag gcggaagcag ccctggccaa cgaaagcgga gcggaagcaa
    10441 gcgttgactc cactgccctc ttcttcgacg cccgtcaagg aactaactcg caggtaacca
    10501 tccagaacaa cctggcagaa ataaccgtag atacaaaagg cgggcgcata gcttcggcca
    10561 cgctgaagga atacatggga caagacaaga cgacccccgt cacactgttc agcggcaatg
    10621 acgcttccat gaatttcctc ttttacaaca agaaagagac tatccagacg gaagactatt
    10681 atttcaccgc agtaaaccgt acggacagta ccgtcaccat gcgtttgtcg gcagacagca
    10741 acagctatat cgactttaca tatcgcatgc acaatgacac atacctgata gactttacta
    10801 ttcaggcagt caatatggaa ggtaagctgg cgactaccaa caattatgtg gacatcgagt
    10861 ggtctcagcg tgcccgtcag atagagaagg gttacaccta cgagaaccgt ctggctgaac
    10921 tgacttacaa aatcaccgga gagggtaccg attatctgtc tgccaacaag aacgacgaaa
    10981 aggaagttcc ggaacgcctg gactggattg ctttcaagaa ccagttcttc tcttcagtat
    11041 ttttggcaga tgccgacttt gaaaagacca aactgagttc caagatggag actcaaggca
    11101 gcggctacat taaggactat tctgcggaga tgagcacgaa gttcgaccct gctggcaagg
    11161 aacctaccca gctgttcttc tacttcggcc ccaatcacta caagaccctg accgcactcg
    11221 acaaggggcg tgacgagaag tgggagctga accgtctggt ctatctgggc tggccgctca
    11281 tccgctggat aaacaaatgg ttcaccatca acatcttcga ctggttgtcc agttgggggt
    11341 tgagcatggg tatcgtactg ttgttcatga cgttaatcgt aaaagctgta gtattccccg
    11401 caacgtggaa aacctacatg tcctctgcca agatgcgcgt actgaaaccg aaaatcgacg
    11461 agataaacaa gaagtacccc aagcaggaag atgccatgaa gaagcagcag gaagtgatgg
    11521 gcctctacag ccagtacgga gtcagtccga tgggcggatg tctgccgatg ctgatacagt
    11581 tccctatctt gatggccttg ttcatgttcg tgccgagtgc cattgaactc cgccagcaga
    11641 gcttcttgtg ggcagacgac ctttccactt acgatgcgtt catcaacttc ccgttccata
    11701 tcccgttcct gggaagccac ctcagcttgt tctgcctgct gatgacggtt accaacatat
    11761 tgaacacgaa gtacatgatg cagcaacagg atacgggtgc caatccgcag atggctgcca
    11821 tgaagtggat gtcatacctg atgcctatca tgttcctctt catattgaac gactatcctt
    11881 cgggattgaa ctattactac ttcatctcta cgttagtcag tgtggtaaca acgctcatca
    11941 tgcgcaagac aaccaatgag gaagcccttc ttgctcagtt ggaagccaac aagaaagacc
    12001 cgaagaagat gaagaaaacc ggtttcgccg ctcgtctgga agccatgcag aaacagcagg
    12061 aacagatgat gaaagaaaaa cagaacaaaa agtagtaaga ctaccgttca agatattctt
    12121 ttgcagaaag ccggacaatg acatttgccc ggctttctta tccttacacc aacgaaaaaa
    12181 ttcacagact ctaaattatg cagactaaat acacttacaa acaaatctgg ctcatagcct
    12241 accctatcct aatcagcctc cttatggagc agatgatagg tatgacggac accgccttcc
    12301 tcgggcgtgt gggcgaagtc gagctgggag catctgccat cgccggtgtc ttctacatgg
    12361 tcatcttcat ggttgccttc ggtttcagca tcggggcaca gatactcatt gcccggcgca
    12421 acggcgaaca gcagtataag gaaatcggtg acttgttcta tcagggcatc tatttccaag
    12481 tcgggatggc gacagtcatg ttcctgctgt cctattgctt ctcgccgatt atcctgaaac
    12541 gcatcgtagc ctcggaacat atctacgaag cagccaccag ctacctgcat tggcgtgtat
    12601 tcggtgcctt cttctcgttc agcgcagtca tgttccgtgc ctttttcttg ggaaccaccc
    12661 agaccaagac actgacactg aactccatcg tcatggtgtt gagcaatgtc gtattcaact
    12721 atatcctgat tttcggtaaa ttcggttttc ctgcactcgg cattgccgga gccgccatcg
    12781 gctcctcatt ggccgagctg gtttcgctgt tattcttcat cctctatacc cgtagccgta
    12841 tcgactgctg caagtacggg ctggaccgta ttccgaagtt ccggctggac gtattgaaac
    12901 ggatgctgaa cgtctctttc tggaccatga tacagaattt cttctccctc tccacctggt
    12961 tccttttctt cctttatgtg gagcatctgg gagagcgctc gctggcagtg accaacattg
    13021 tccgcaacgt gtccggcata ctgttcatgg tactcatggc atttgcctct acctgcgggt
    13081 cactggtcag caacctcatc ggtgcaggcc actccgattg cgtggcaggc accatccggc
    13141 agcacgtacg catagcctac gtcttcgtac ttccgctggc attgcttttc gcggtgttcc
    13201 ccaagctgat tctgggaatt tataccgaca tacccgacct gcaggacgct gccgtacatt
    13261 cgctctgggt gatgtgctcc acctatctgt tcctggttcc tgccaatgtc tatttccagg
    13321 cagtttccgg aaccggcaac acgcgtacgg catgggggtt ggagatggct acgctggtca
    13381 tctacacagc ctatatcacc tacattattc tgattctgca actcgacgtg gccatttgct
    13441 ggacctcgga aatggtttat tccagcttta ttctcatttt ctgctggcta tatatcaaac
    13501 gtgggaattg gcaaggaagg aaaatttagt atctttgcat tgaaataacc gaaacaaaaa
    13561 acatatatga aacaagtaaa tctactactt atgtcagcag ccatgacatt ggcctcctgc
    13621 ggaggaacaa aagatgccgg acagcagcag gacgcagcag cgctcatcca gcggtcggac
    13681 atcaagattg aaggaaagcg tatgacaccc gaggcactct gggcgatggg acgtatcggc
    13741 agtgtagccg tatctcccga cgaaaagcaa attgcctaca cggtatccta ttacagcgtg
    13801 ccccagaaca agagtaacag cgaagtcttc gtcatgaatg ccgacggtag tggcaatacc
    13861 cagataacgc atgacgcctg gcaagaagga cagcccacat ggttcaagga cggcaagaag
    13921 cttgccttcc tctgcaacga aagcggcagc agccaggtat gggaaatgaa tcccgacggc
    13981 agcggacgca agcagctgac tcaatacgag ggagacatcg aagggttctc tttctcgccc
    14041 gacggcaaga aactcctttt cattgcccag gtaaagaccg tgaagagtac ggcagacaaa
    14101 catccggacc ttcctaaagc caccggcatc atcgttaccg acctgatgta caagcattgg
    14161 gatgaatggg tgactactgc tccccatccg tttgttgctg atttcgacgg caatgccatc
    14221 agcaatgtca ctgatattct tgagggagag ccatacgaaa gcccgatgaa gccctggggc
    14281 ggtatcgagc agctggcatg gagcccgtct tctgataagg tggcctatac atgccgtaag
    14341 aaaaccggac tggcgtatgc catttccacc aactccgaca tttatatcta cgaccttgcc
    14401 tccaaggaaa ccaaaaacat cacggaagaa aacaagggat atgatacgaa tccccaatac
    14461 tctcccgacg gcaaatacat cgcctggcag agcatggaac gtgacggcta cgaagccgac
    14521 ttgaaccgct tgtttatcat gaacctcgag accggtgaga aacgttttgt aagcaaagct
    14581 ttcgaatcga acgtggacgc cttcttgtgg aacaaagatt cccagagcat ctacttcatc
    14641 ggtgtatggc atggcgagac acagatttac aacatcgacc ttgccggaaa cgacaagctt
    14701 acccagctca ccgacggcat gcacgactat gcttcactcg ccctttgcgg agacaagatt
    14761 atcgccaaac gccactccat gagcatgggc gacgaaatct atgccgtaaa cagtgcacgc
    14821 aacggcgacg cttttgcaga agcagtgcaa ctgaccacag aaaacaagca gatttacgac
    14881 cagctggaaa tgggtaaagt ggaagcccgc tggatgaaga ccaccgacgg caagcagatg
    14941 ctgacctggg tgatttatcc tccacagttc gaccctaaca agaagtaccc caccctcctc
    15001 ttctgtgaag gtggtcctca gagtcccgtc agccagttct ggagctaccg ttggaatttc
    15061 cagattatgg cggcaaacga ctatatcatc gtagctccca accgtcgtgg tcttccgggc
    15121 ttcggtgtag agtggaacga agccatcagc ggtgattatg gcggccagtg catgaaggac
    15181 tacttcactg ccattgacga aatggcgaaa gaacctttcg tcgacaaaga ccgcctgggt
    15241 tgcgtaggtg ccagcttcgg aggtttctcc gtatattggc ttgccggaca ccatgacaaa
    15301 cgcttcaagg cattcatcgc acacgacggt atcttcaaca tggaaatgca atatctggaa
    15361 acggaagaga aatggtttgc caactgggat atgggcggcg cttattggga aaagaacaac
    15421 gctacggcac aacgcacttt tgccaactcc ccgcatctct tcgtcgacaa atgggacacc
    15481 cctatcctct gcatccacgg agagaaggac ttccgcatcc ttgccaacca ggcaatggcc
    15541 gccttcgatg cagccgtgat gcgtggcgtt cctgccgaac tgcttatcta tccgg
//
