LOCUS       c00026_gnlPro..        16797 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MHPDFDEB_26.
ACCESSION   c00026_gnlPro..
VERSION     c00026_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 13:35:00
            Original ID  :: gnl|Prokka|MHPDFDEB_26
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16797
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16797
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3239:6797](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(3240..6797)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16797
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16797
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             133..2898
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_1"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.2e-16, bitscore:
                     52.0, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKMRQHNLRILFFLLVLWGVAVACSRREARFRIGVSQCSEDEWRR
                     QMNSEILREAHFYEDVEVDIRTAVDDNDRQAKDIRELIAEGVDLLIVAPNEATPITPVV
                     EEAYNRGIPVIVVDRKILSDKYTAYVGADNYEIGKAVGEYVANVLHGQGDVVEISGLVG
                     STPAVDRHQGFVKAISAYPGIRLLAVEDGAWLQLKAGEKMDTLLSRFPHIDLVYAQNDR
                     MAAGAYAAAAREGREKDMRFIGIDALSGKDYGVEKVLAGELDATFIYPTGGDRVMQIAM
                     DILNKRDFPRETILGTSVVDRDNALIMKMQTAHIGTLDGKIETLNGKINQYLASYATQQ
                     VVLYGSLSALLLLVGLLVAVYLSLRAKNRLNRELSMQKKKLEEQKTQLIQQKELLEVQK
                     SQLEQLSHELEEATHAKLVFFTNISHDFRTPLTLIADPIEQLLANRTLDGQPRQLLELM
                     KKNVHILLRLVNQILDFRKVENGRMELHLEPFDLLDSFRGWNDSFRMALLKKHIAFSFE
                     ASPDTDFRMMADAEKMERIYFNLFSNAVKYTPENGKIAIRLSMTEQNYSLSVFNSGSYI
                     SSTDVEAIFERFYQVDGHQAGTGIGLALVRAFVEMHGGNIAAHSDDKGTTFTVTFPKQD
                     VLQYHPTIVTLPAEEKDVSSTLIDTEVKACEEVVEADCPTVLVIDDNADIRNYVKSLLS
                     NEFRVLDAADGTEGIRLAMKYVPDVIISDVMMPGMDGVECCRRLKGELQTCHIPVILLT
                     ACSLDEQRIQGYDGGADSYISKPFNSQLLLSRVRNLIANRRQLRQFFGDNQTIEKEAIS
                     DLDKGFVSRFKSLVEERMKDAELNVEDLGRNMGMSRVQLYRKLKSLTNYSPNELLRQMR
                     LKKAASLLASSDMTVAEIAYEVGFSSPSYFTKCYKEQFGESPTEFLKRRG"
     CDS             complement(2961..3149)
                     /locus_tag="ctg26_2"
                     /transl_table=11
                     /translation="MIGFIIWIIGVVLCVKAVLEIMKWPVDGVKKLLVAIIILLTSWIG
                     ICVYYFWGRENLPQILK"
     CDS             complement(3240..6797)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_3"
                     /sec_met_domain="PFOR_II (E-value: 6e-19, bitscore: 59.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 2.7e-82, bitscore: 267.0,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 2e-31, bitscore: 100.5,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.4e-12, bitscore: 38.8,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.4e-07, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 8.3e-26, bitscore: 80.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KARVPFMNFFDGFRTSHEIQKIEMLENEDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGLVAVHLYRPFSAKHFLAAVPKTAKKIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILAVYKNLAMPMPKNHFTIGIVDD
                     VTFTSLPQEEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNITVYYINATQIAQEIGLGNRTNTILQSAFFRITGVIPV
                     DLAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKQLTVDPAWANLADDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWEQGTAKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGANFTQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADV
                     CPGNPKKGGKALTMKHLESQLPEAANWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTKNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKAMEDAIAAEGTPAEYKEVFQAWIENMYDADKSKE
                     LAEKIIPMVEAAKDKCDSCKTIASLSQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQAEEEKAVKCGYWHLWR
                     YNPALEAEGKNPFTLDSKEPDWSGFQDFLKGEVRYASVMKQYPQEADELFKAAEENAKW
                     RYNSYKRLSKENWGAEVTE"
     CDS             complement(6839..8017)
                     /locus_tag="ctg26_4"
                     /transl_table=11
                     /translation="MEAFYRTHAYLVEHTNAPVRRDLMDEIDWNDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGTDRSCLFINMNNFYFSGHGIVEFAAEFQRRGGKVLLIDQVFKYPEWS
                     KELRMCYDRFPNLKIVFTGSSVMRLKEENMELRDIVKSYNLRGFSFREYLNLQTGMKFH
                     AYPLEEILSNHEQIAKGILSKVRPLDYIQDYMHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLANDIQTSRATVMNYIKYLADAR
                     LINMVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANTMWKDHKVNKGD
                     KNISFMVDEVMPFNICPEGTKIKNNPGVTYVLHKAEIGRGNQIPLWLFGFLY"
     CDS             8209..9354
                     /locus_tag="ctg26_5"
                     /transl_table=11
                     /translation="MAPATIRRMAEDLALLPIWYAQPGSGVLASSAYNADYLKQMQQLF
                     RLDVHLVTEPELPDYADVRVMPWGWNPAIRKRMLKGGVLEKNLPTPDALDKYRMKAARS
                     NALAFRALFYSNKIDYTCGDGCCLVEADGGTTAISLDIIGRYKEGCVFKSLWSGSGKGL
                     CWCRHGFTKNVSDWCSRALKENGGFVMEPIFDKVEDFAMEFYSDGRGKLLFVGYSRFVT
                     DDKGAYRGNILTSDGQVEEWIQQYVPFEAFVRIRNMMQKALETGYATSYTGFLGVDMMV
                     CRQKEGHPYAINPHVEINLRMNMGIVSHVLSDHFIVPGGEGRFSIDCFPTHEALMERHE
                     QDAQSYPLVVKDGRVVSGYLPLVPVTPKSRYRAFVCVTAAE"
     CDS             complement(9338..10846)
                     /locus_tag="ctg26_6"
                     /transl_table=11
                     /translation="LLIFAEKYDRNKEEKRKMKRIISILLYMAVLLPLAAQPPKHEVRA
                     AWITAVYGLDWPQTRATSPEGIRKQQAELIEILDRLKAANFNTVLFQTRTRGDVLYKSA
                     IEPYNSILTGKVGGDPGYDPLAFAIAECHKRGMECHAWMVTIPLGNRKHVAALGKESVT
                     KKKRAICVPYKREYFLNPGHPQTKEYLMSLVREVVERYDVDGIHFDYLRYPENAPRFPD
                     SYDYRKYSKGRSLAQWRRDNLTEIVRYIYKGVKVMKPWVKVSTCPVGKYKDTSRYPSRG
                     WNAFHTVYQDVQGWLGEGIQDQIYPMLYFRGNHFYPFALDWQEQSNGRQIIPGLGIYFL
                     DPSEGNWTLDEIERQMHFIRAHGLAGEAHYRVKYLMDNTQGLYDALEEDFYTAPALQPA
                     MPWIDNVAPTPPAGLTVETPENGYWKLSWQPATDNDKRNVPMYVIYGSDTYPVDTSNPE
                     NILAQRVQGTEYTYAPIRPWTARKYFAVTAIDRCGNESKAIQQQ"
     CDS             10918..12348
                     /locus_tag="ctg26_7"
                     /transl_table=11
                     /translation="MITFTLCLLALIAGYFIYGRFIERVFGPDDRKTPALTKADGVDYI
                     PLPTWKIFMIQFLNIAGLGPIFGAIMGAKFGTASYLWIVLGSIFAGAVHDYLAGMLSLR
                     HDGESLPEIIGRYLGLTTKQVMRGFTVILMILVGAVFVAGPAGLLAKLTPDSLDTTFWI
                     IVVFAYYIFATLLPVDKIIGKIYPLFAVALLFMAVGILVMLYVNHPALPEIWDGLQNTH
                     PDAVALPIFPIMFVSIACGAISGFHATQSPLMARCMTSERHGRPVFYGAMITEGIVALI
                     WAAAATYFFHENGMGETNASIIVDAITKDWLGAVGGVLAILGVIAAPITSGDTAFRSAR
                     LIVADFLGMEQKSMRRRLYICIPMFLVAISLLLYSLRDKDGFDMIWRYFAWANQTLSVF
                     TLWAITVYLVREKKGRYYYVTYFPALFMTAVCTTYICIAPEGFGLGPNYALGIALIAVV
                     LAAIWFNIWYFKTTKKLW"
     CDS             12348..12569
                     /locus_tag="ctg26_8"
                     /transl_table=11
                     /translation="MKKIKKSTGLTLALLIYVSATAAYFLPRNTEISDTEKYVTVAASY
                     LIVFVLWLVLRKKEALQRKRFEEDNKQH"
     CDS             12595..13083
                     /locus_tag="ctg26_9"
                     /transl_table=11
                     /translation="MKKLALFVCLLVVTVAAQAQFEKGKWILNPSITGLEFSHDTGTDK
                     TSFGLEAKGGAFLLDNIALLVHAGAAWNTGGSDLDVYTLGVGGRYYFDKIGVYLGADVN
                     VDRWDWGHDLDDTKFSFGLEAGYAFFLTRTVTIEPAAYWNINDDRSKFGLKVGFGFYF"
     CDS             13194..13502
                     /locus_tag="ctg26_10"
                     /transl_table=11
                     /translation="VIDKNRYTYLSRPFRFHFNCTAYFFHWRYYLSYQFFPTAKFCTLF
                     AVSLHEACSSSAIRLQSYCNGRAAALQKECSDFAVAMQCLLAVIFSILIPLLHVFLI"
     CDS             13587..14765
                     /locus_tag="ctg26_11"
                     /transl_table=11
                     /translation="MNRVCFLLLLCCLSSCKMNKTERVEMPEDSVDTVGLDRRLQEKSV
                     SDSLKIGLVDDGDCLQKQLLAIHDELRKRLENTTYTHIRRNVTGYGVGMHCIDIDLMVN
                     TPERQKEFREKIMDSPVFCFHGVEVPVINERVGRNHIRGIHIRPEYPVFSTKALHATFI
                     LSNHSGGDLTCGEHYYLTFEDEKGTWRELPINAAFWDIAYVLRDGEERVMKASLYPDVH
                     PNKPGRYRYFYEITIRRKPVLMMAEFRLTDNEEEWRTAEKTSLPPYISDAGKGGSPQLI
                     TEEPMEEPVYKVVEVMPEFPGGMKALMDFIQKNIRYPEEVRKNGIQGRVAVSVVIDENG
                     RVTDPVIMRSRYPALDEEALRIVELMPQWKPGMQQGKAVKVEFTFPVTFKLE"
ORIGIN
        1 atggcaaaat cctgagcaac tttttgttgc tcaggtactt aaaaagttta atttataata
       61 gtgttgcgga attaaggttc ttttcacatt tttcgttatc tttgctcatc tgcaatctta
      121 aatcagagga aagtgaagat gagacagcat aaccttcgga ttttattctt tttgctcgtg
      181 ctttggggag tggcggttgc ctgctcccgg cgcgaggcac gtttccgtat cggcgtttcc
      241 caatgtagcg aggatgaatg gcggcgccag atgaacagtg agatactccg tgaagcccat
      301 ttctacgagg atgtggaggt ggacatccgt actgctgtcg acgataatga ccgtcaggca
      361 aaagacattc gtgagctgat agccgaaggg gtggatctgc tgattgtggc ccctaatgaa
      421 gccactccga taactccggt tgtggaggag gcatacaacc ggggcattcc ggtgattgta
      481 gtggaccgta aaatcctttc ggacaaatac acggcctacg tcggtgcaga caactacgag
      541 atagggaaag ctgtgggaga gtatgtggcc aatgtgctgc atgggcaggg agatgtggtg
      601 gaaatctcag gtttggtggg ctccacacct gccgtagacc gtcatcaagg atttgtgaag
      661 gctatatccg cttatcccgg tatccggttg ctggccgttg aagacggtgc ctggttgcaa
      721 ctcaaggccg gagagaaaat ggatactctg ctgagccgct ttccgcatat cgacctggtg
      781 tatgcgcaga atgaccgtat ggcggccgga gcctatgctg ccgctgcccg agaggggcgg
      841 gaaaaggata tgcggttcat cggcatagac gccctgtccg gcaaagacta tggagtggag
      901 aaagtgcttg ccggcgaact ggatgccacg tttatatatc ctaccggtgg cgaccgcgtg
      961 atgcagattg ccatggatat cctgaacaag cgtgatttcc cccgtgaaac tatcctgggc
     1021 acttccgtcg tcgaccgcga caatgctctc atcatgaaga tgcagaccgc ccacatcggc
     1081 accctggatg gaaagataga aaccctgaac ggaaagataa accagtattt ggccagttat
     1141 gccacgcagc aggttgtctt gtacggcagt ctgtctgccc tattgttgct ggtcggtttg
     1201 ttggtggctg tctacctctc cttgcgtgcc aagaaccggt tgaaccgtga gctgtccatg
     1261 cagaaaaaga aactggaaga acagaaaact cagttgatac agcagaagga actgttggaa
     1321 gtgcagaagt cgcagttgga acagctttcc catgaactgg aggaggctac gcacgccaag
     1381 ctggtgttct tcacgaatat ttcacacgat ttccgtactc cgctgacgct gatagccgat
     1441 cccatagagc agcttcttgc caaccgcacc ctcgacggac agccgcgcca gctcctcgag
     1501 ctgatgaaaa agaatgtgca tatcctgctt cgcctggtca accagatact tgatttccgg
     1561 aaggtggaga acgggcgcat ggagctccat ctcgaacctt ttgatttgct cgacagcttc
     1621 cggggctgga acgactcttt ccgcatggcg ttgctgaaga aacatattgc tttcagcttt
     1681 gaggcatctc ccgatacgga cttccggatg atggcggatg cggagaagat ggagcgcatt
     1741 tacttcaatc tcttctccaa tgccgtgaag tatacgccgg agaacgggaa gatagctata
     1801 cgcttgtcaa tgacagagca gaactatagc ttgtctgttt tcaattccgg cagttacatt
     1861 tcttcgaccg atgtggaagc tatcttcgag cgtttttatc aagtggacgg acatcaggca
     1921 ggtaccggta tcggccttgc gctggtacgt gcttttgtag agatgcatgg tggcaacatt
     1981 gcggcacaca gtgatgataa gggtactacc ttcaccgtca ctttcccgaa gcaggatgtt
     2041 ttgcagtacc atcccaccat agtgacgttg cctgccgaag agaaggacgt gtcgtccacc
     2101 ctgatagata cggaagtgaa ggcatgcgaa gaggtggttg aggctgattg tcctactgtg
     2161 ctggtaattg acgataatgc ggatattcgc aactatgtga agtctcttct gtcgaacgag
     2221 ttccgtgtat tggatgctgc ggacgggaca gagggtatcc ggctggccat gaagtatgtg
     2281 ccggatgtga ttatctccga tgtaatgatg cccggtatgg atggtgtgga atgctgccgc
     2341 cgcttgaagg gggagttgca gacatgccat atcccggtga ttctgctgac ggcctgctcg
     2401 ctggacgaac agcgtatcca gggctatgat ggcggtgccg attcttatat ttccaaacca
     2461 ttcaattcgc agttgctctt gtctcgtgtc cgcaatctta ttgcaaaccg ccgtcagttg
     2521 aggcagttct tcggagataa ccagactatc gagaaggaag ccatcagtga tttggataag
     2581 ggtttcgtct cccgcttcaa atcgcttgtc gaggagagga tgaaagatgc ggaactcaat
     2641 gtggaggatt tgggacggaa tatgggtatg agccgtgtgc agctttaccg taagctgaaa
     2701 tcgctgacca actattcgcc gaatgagctg ctgcgccaga tgaggttgaa aaaggctgcc
     2761 tcactgcttg cctcctctga catgacggta gcggagattg cctatgaagt gggcttttcg
     2821 tcaccttcct atttcacgaa atgctataag gaacagtttg gggagagtcc taccgagttt
     2881 ctgaaaagaa ggggatagct gttgtctatc ccccttgttc ttaatacacg tctgtttact
     2941 tctgtaaatg atactggaac ttatttcagt atttgaggca ggttttccct tccccagaag
     3001 tagtaaacac agattccaat ccagcttgtg agcaggatga taattgcaac taatagtttc
     3061 ttcacgccgt ctaccggcca cttcatgatt tcaagtacgg ctttgacaca cagaaccaca
     3121 ccgataatcc aaatgataaa tccaatcata acctgtgata tttagtattg ttaattaaaa
     3181 acaaatagag actacgcctt attcaggagc agcctctatt ctttatttag taatcggaat
     3241 tactctgtaa cttcagcgcc ccaattttct ttggaaagac gcttgtagct gttgtaacgc
     3301 catttagcgt tttcttcagc agccttgaac agctcgtcgg cctcctgcgg atattgcttc
     3361 attacggatg cgtaacgaac ttcacccttc aggaagtctt ggaatccgct ccaatccggt
     3421 tccttgctat ccagcgtgaa cggattcttg ccttcagcct ccagagccgg gttgtaacgc
     3481 cacaagtgcc agtaaccgca cttaacggcc ttttcttcct ctgcctggct cttacccata
     3541 cctgccttca gaccgtggtt gatacacgga gcgtaagcga tgatgagtga cggaccggga
     3601 tatgcttctg cttcacggat agccttcagg gtctgagcct ggtcggcacc catagcgatt
     3661 tgggcaacgt atacgtaacc gtaagtagta gccatcagac cgaggtcttt cttgcgtaca
     3721 cgcttaccgg cagcggcaaa cttggcgata gcgcctaccg gggtagcctt ggaagactga
     3781 ccgcctgtgt tggagtaaac ctcagtatcc agtacgagga tgttgacatc cttaccgctt
     3841 gcgattacat ggtcgagacc accgtaaccg atgtcgtaag aggcaccgtc gccaccgata
     3901 atccactggc tgcgttttac caggtattga gacagactgg cgatagtctt gcagctgtcg
     3961 cacttgtctt tggcagcttc taccatcgga ataatctttt cagccagttc cttgctcttg
     4021 tctgcatcgt acatgttttc aatccaagcc tggaatactt ctttgtattc agccggagtt
     4081 ccttctgctg cgatggcatc ttccatagcc ttcacgatac gtgcgcgcat cttttcgttg
     4141 gcaagctcca tacccagacc gaattcgcag aagtcctcga acaatgagtt agcccaagca
     4201 ggaccgtgac ccttttcgtt cttggtataa ggagtagaag gtactgaacc ggagtagatg
     4261 gaagaacatc ctgttgcgtt ggctaccatt tcgcggtcac cgaacaactg ggaaatcagc
     4321 ttcacatacg gagtttcacc acaaccggag caagcacctg agaactcgaa caacggagtg
     4381 gcgaactgag agttcttcac gttggccttg atgtcaacca agtgttgttt gctcttcacg
     4441 ttttcagcac agtaagtcca gttggcagct tccggcaatt ggctttcgag gtgcttcata
     4501 gtcagagctt tgccaccctt cttcgggttg cccggacaga catcggcaca gttgccacaa
     4561 cccagacagt cgagaacgtc tacctgaata cggaatgtca taccgtcgaa tgctttacct
     4621 acagccttca gttgagtgaa gttggcaccc ttctgctctt cagcatcgag tacgaacgga
     4681 cggatggaag cgtgaggaca aacgtaagca cacttgttac actggataca gttctcagcg
     4741 ttccattcgg gaacgaatgc ggctacacca cgtttctcat atttggcagt gccttgttcc
     4801 caagtaccgt cttcaatacc cttgaaagcg gataccggca ataagtcacc gtcttgtgcg
     4861 ttgataggac gaaccacttc gttgatgaat gcaggatcgt tgttttcagc cttggcgtcg
     4921 tctgccagat tggcccaagc cgggtcaacg gtcagttgct tgtattcgcc gccacggtca
     4981 actgctgcgt agttcttgtt gacaacgtct tcacccttct tgccgtaaga cttaacgatg
     5041 aatttcttca tctgttctac agccaggtca accggaataa cgccggtgat acggaagaat
     5101 gcggattgca ggatggtgtt ggtacggttg cccaaaccga tttcttgtgc aatctgagta
     5161 gcgttgatat agtaaacagt gatattgttc tgtgcaaagt acttcttcac cttgttgggc
     5221 aggttcttgg caagctcttc gccttcccag atggtgttca gcaagaaaga gccgttctta
     5281 cgcaagccgc gggttacgtc gtacatgtgc aggtaagctt gaacgtggca agccacgaag
     5341 ttaggcgtgt ttaccaggta tgtagagcgg ataggagtat caccgaaacg caggtgcgag
     5401 caggtgaaac cgcctgattt cttggagtcg taagagaaat aagcctggca gtgcttgtcg
     5461 gtattgtcac cgataatctt cacagagttc ttgttggcac ctactgtacc atcagcgccc
     5521 aaaccgtaga atttggcttc gaacatgcct tcgccgccca atgcgatttc ttcttcctgg
     5581 ggcagagaag tgaaggtaac gtcgtctacg ataccgatag tgaagtggtt cttcggcatc
     5641 ggcatagcca ggttcttgta aacggcgagg atttgcgcgg gagtagtgtc cttggatccc
     5701 aaaccgtaac ggccgcctac gataaccgga gcattctctg caccgtagaa gcagtctttt
     5761 acgtcgaggt acaacggttc gccgttagca cccggttctt tcgtacggtc cagtacggca
     5821 atcttcttgg cagtcttggg aacggcggca aggaagtgct tggcagagaa cggacgatac
     5881 aagtgaacgg caaccaaacc aaccttttcg ccattggcaa cgaggtggtc gatagcttcg
     5941 cgggcagctt ccgttacaga acccatggcg atgataacgc gttctgcatc ttctgcaccg
     6001 tagtaatcga acaaaccata cttgcggcct gtgattttgg aaatctcgtt catgtattcc
     6061 tcaacgatag ccggaactgc ttcatagtag ttgttgcaag attcacggtg ttggaagaag
     6121 tggtcaggat tttcggccat accacgggca accgggttca tcgggttcaa tgcacgtgcg
     6181 cggaattcag ccaaagcttc ctggtcgata agcggagcga ggtcttcgtt ctccaacatt
     6241 tcaatcttct ggatttcgtg agaagtacgg aagccgtcga agaagttcat aaacggaaca
     6301 cgggccttga tggtggctag gtgggcaaca cctgccaagt ccataacttc ttgtacagaa
     6361 ccttcggcca acatggcaaa accagtctgg cgtgcagaca taacgtcctg gtggtcaccg
     6421 aagatacaca gtgcatggct tgccaatgta cgtgctgata cgtggaatac acaaggcagg
     6481 aattcaccgg caatcttgta catgttcggg atcatcagca acagaccttg tgaagctgtg
     6541 taagtagtag tcagcgcacc ggcttgcaga gagccgtgga cggcacctgc agcaccacct
     6601 tctgactgca tttcctgtac caatactgtt tcgccgaaga tgttcttgcg acctgcggca
     6661 gcccattcgt ctacgtattc agccatcgta gaagaggggg tgatggggta gatggcagct
     6721 acttcggaga acatatacga gatatgtgca gcagcctggt taccatcaca agtaatgaat
     6781 ttcttctgtt tagtcataac taaattgaat tatttattta agtaaaaaaa tctctctctt
     6841 aatacaagaa accgaataac cagagaggta tttggttgcc tcggcctatt tctgccttat
     6901 gcagtacata agtaactccc ggattattct ttatctttgt tccttccgga caaatattga
     6961 aaggcatcac ctcatctacc atgaacgaga tgttcttgtc gcccttgttc accttgtggt
     7021 ccttccacat tgtgttggca aagaaagtgt ccagtacgtc ttgctcttcc accttgacgg
     7081 gatagatgga atacatcaga tttgaattgt gcatcattat cttcgacggc ttcttgggga
     7141 attcttctcc cttcggatag accatattga tgagtcgtgc gtctgccaga tacttgatgt
     7201 aattcattac tgtggcgcgg gaggtctgta tgtcgtttgc cagttggctg acattcggcg
     7261 ctttcggccc gtccacggcc aacaaatata gtaatttctt tatcttcgaa aggtatttca
     7321 gctcaatttg tttgatgagc aggatatcca cttccaccat catgttcatc gtcttgagca
     7381 gattctccga aaagttacgc ttttcaagga agaaagggta gaagccgtgg tgcatatagt
     7441 cttgtatgta gtccaatgga cgtactttgg agaggatgcc tttggctatc tgttcgtggt
     7501 tgctcaggat ttcttccaac ggataggcat ggaacttcat gcccgtctgc aggttcaggt
     7561 attcgcggaa ggagaagccg cgcaggttgt agctcttcac gatgtcgcgc aactccatat
     7621 tctcctcttt cagacgcatc acggacgagc cggtgaacac gattttcagg ttggggaagc
     7681 ggtcgtagca catacgcagt tccttgctcc attccgggta cttgaatacc tggtctatca
     7741 acagcacttt tcctccgcgg cgctggaatt cggcggcgaa ctccacgatg ccatgtccgg
     7801 agaagtagaa gttgttcatg ttgatgaaga ggcaggagcg gtctgtgccg aatttctctt
     7861 tggcatattg cagcaagaaa gtagtcttac ctacgcctct tgtgcctttg ataccgataa
     7921 gacggtcatt ccagtctatt tcgtccatta ggtcgcggcg tacgggggca ttggtatgct
     7981 ctacgagata agcgtgtgta cggtaaaatg cttccatgct ttaaattcgg tttatcgggc
     8041 gacaaatata cggctttttt atagatttgc aaagtagaga tggcaaaata ttatataact
     8101 ttgcactctc atacaaaacg tgagtaattg gttaacattt gaaagatgaa actttatgtg
     8161 ttcaatcctg atgcagatat ggcattggga aataatgaag aaaattatat ggcgcccgct
     8221 accatccgcc gtatggctga agacttggct ttgttgccga tttggtatgc ccagccgggt
     8281 agtggggtac tggcctcttc cgcctataat gcagattatc tgaaacagat gcaacagttg
     8341 ttccggctgg atgtgcattt ggtgacagag ccggagctgc ccgattatgc tgatgtgcgg
     8401 gtaatgcctt ggggatggaa ccccgctatc cgtaaacgga tgttgaaagg cggtgttctg
     8461 gaaaaaaatc ttcctacgcc ggatgctttg gataaatatc gtatgaaggc tgcccgtagt
     8521 aacgctttgg cttttcgtgc acttttctat tccaataaaa tagattatac ttgtggtgac
     8581 ggttgttgct tggtggaggc tgatggtgga actacggcta tctctctgga tattattggt
     8641 cgttacaaag agggatgtgt gtttaaatca ctttggtcgg gaagtgggaa gggattgtgt
     8701 tggtgccgtc atggctttac gaaaaatgtt tccgattggt gtagtagggc gctgaaagaa
     8761 aatggaggtt ttgtgatgga gcctatattt gataaggtgg aagattttgc catggaattt
     8821 tattcggatg gccggggaaa gcttcttttt gtcggctatt cccgttttgt tacggatgac
     8881 aagggggctt atcgtggtaa tatccttact tcagatgggc aagtggagga atggattcag
     8941 caatatgtgc cctttgaagc atttgtgcgc atacgcaata tgatgcagaa ggcattggaa
     9001 acgggttatg ctacatctta tacgggtttt ttgggtgtgg acatgatggt ctgccgtcag
     9061 aaggaagggc atccgtatgc catcaacccc catgtcgaaa taaatctacg gatgaatatg
     9121 ggaatcgttt cccatgtgct tagtgatcat ttcattgtcc ccggtgggga gggacgtttc
     9181 tccatcgatt gctttccgac ccatgaagct ttgatggagc ggcatgagca ggatgcgcaa
     9241 agttatccgc tggtggtgaa ggacggcagg gttgtttccg gctatctgcc tctggttccg
     9301 gtcactccga agagccgtta ccgggctttt gtctgtgtca ctgctgctga atagctttgc
     9361 tttcgtttcc gcaacggtct atggctgtca cggcaaaata ttttcgggca gtccacgggc
     9421 ggatgggggc ataggtatat tccgtgcctt gtactcgttg tgccaggata ttctccggat
     9481 tggaggtatc tacgggatag gtgtccgaac cgtagattac atacatcgga acattccgct
     9541 tgtcattatc cgtggcgggt tgccagctta gtttccaata gccgttttcc ggtgtttcca
     9601 ccgtgagtcc ggcgggaggt gtaggagcta cattgtctat ccacggcatg gcgggctgca
     9661 gggccggggc ggtatagaag tcttcttcca gcgcatcata aagcccttgc gtattgtcca
     9721 tcagatactt cacgcggtag tgtgcctcgc ccgccagacc gtgggcgcgg ataaagtgca
     9781 tctgccgttc aatctcgtcc agcgtccagt tcccttcgct ggggtcgagg aagtagatgc
     9841 ccagaccggg aatgatttgg cgtccgttac tttgttcctg ccagtcgagg gcaaagggat
     9901 agaaatgatt gccgcggaaa tagagcatcg gataaatctg gtcctggatg ccctcgccca
     9961 gccaaccctg cacgtcttga tagacggtgt ggaaggcatt ccagccacgg gaggggtagc
    10021 gggaagtgtc tttgtatttt cctaccgggc aggtgctgac ctttacccag ggtttcatga
    10081 cttttacacc tttatatata tagcgtacta tttccgtcag gttgtctctg cgccattggg
    10141 caaggctgcg tcctttgctg tatttgcggt agtcgtagct gtcgggaaaa cggggggcgt
    10201 tttccggata gcgcaggtag tcgaagtgta tcccgtctac atcgtagcgt tccaccactt
    10261 cgcggacaag actcatcagg tactctttgg tttgcggatg tccgggattc aggaagtatt
    10321 cgcgtttgta gggtacgcag atggcgcgtt tctttttggt gacggactct ttaccgaggg
    10381 cggctacatg cttgcggttg cccagaggga tggtcaccat ccaggcatgg cactccatac
    10441 cgcgcttgtg gcattcggct atggcaaaag ccagcggatc gtagccgggg tcgccgccca
    10501 cctttccggt cagtatggag ttgtagggct cgatggctga tttgtagagg acatctcccc
    10561 gtgtacgggt ctggaacagt actgtgttga aattggcggc tttcagtctg tccaatattt
    10621 caatcagttc ggcctgttgc ttgcggatgc cttcgggcga agtggcgcgt gtctgcggcc
    10681 agtccaggcc atagacggca gttatccagg cggcacgcac ttcatgcttg ggcggttgcg
    10741 cagccagtgg cagcaagacg gccatatata gtaaaatgga aataattcgt ttcatttttc
    10801 tcttttcttc tttatttctg tcatatttct cggcgaagat aagcaaaaca cccgattatt
    10861 ttgtgctgtt tacttggaaa ctgttacatt tgcatacatt aaagatatta acacgccatg
    10921 attacattta cgctttgcct gctggcgttg atagccggct attttatcta cggacgcttc
    10981 atagaacgcg tctttggtcc cgatgaccgc aaaacacccg cccttaccaa agccgatggt
    11041 gtggattaca ttccactgcc tacttggaaa atctttatga tacagtttct caatattgcc
    11101 gggttgggac ctatcttcgg tgccatcatg ggagccaagt tcggtacggc atcctatctg
    11161 tggattgtac ttggcagtat ctttgccggt gcagtgcacg actatcttgc cggtatgctc
    11221 tccttgcggc atgacgggga aagcctgccg gaaatcatcg gacgctatct ggggctgacc
    11281 accaagcagg tgatgcgcgg ctttaccgtc atcctgatga tattggtggg agctgtcttt
    11341 gtggcagggc cggccggact gcttgccaag ttgacccccg acagcttgga taccaccttc
    11401 tggattattg ttgttttcgc ttattatatc tttgccactt tgctgccggt agataagatt
    11461 atcggtaaga tatacccgct gttcgccgtt gccctgctgt tcatggcggt cggtattctg
    11521 gtaatgcttt acgtcaacca tcctgcattg ccggagatat gggacggatt gcagaacacg
    11581 catcccgatg cggttgcatt gcccatcttc cccatcatgt tcgtcagcat tgcctgcggt
    11641 gccatcagtg gcttccatgc cacgcagagt ccgctgatgg cacgttgcat gacaagcgag
    11701 cgccacggac gccccgtttt ctatggggca atgataaccg aaggcattgt agccctgata
    11761 tgggctgccg ccgccactta tttcttccac gagaacggga tgggggagac gaatgcctct
    11821 atcattgtag acgccattac aaaagactgg ctgggtgccg taggtggcgt attggccatt
    11881 ctgggtgtta ttgccgcgcc tattaccagt ggcgacacgg ctttccgttc agcgcgcctc
    11941 attgtggcgg atttcttggg aatggaacaa aaatccatgc gtcgccgttt atatatatgc
    12001 atcccgatgt tcctggtagc cattagcttg ttgctttaca gcctgcggga caaggatgga
    12061 tttgatatga tttggcgtta ttttgcctgg gccaatcaga ctctgtccgt ctttacgttg
    12121 tgggccatta cggtctatct ggtacgcgag aagaaaggac gttattatta cgtcacctat
    12181 ttcccggcat tattcatgac ggctgtgtgt accacttaca tctgcattgc tcccgaaggt
    12241 ttcgggctcg gtccgaatta tgcgctgggc atagccttga tagctgttgt gctggctgct
    12301 atttggttta atatttggta ttttaagacg actaaaaaac tttggtaatg aagaaaatca
    12361 agaaatctac cgggctcacg ttggccctgc ttatttacgt ttctgctact gccgcttatt
    12421 tccttccccg caatacggaa atcagcgata ctgagaagta tgtcaccgta gctgcttcgt
    12481 acctcattgt atttgtgctg tggctggtgc ttcgcaagaa ggaggcgctg caacgcaagc
    12541 gattcgaaga agacaataaa caacattgat tattcactca aaaaacagaa caagatgaaa
    12601 aaactggcat tattcgtttg cttgcttgtt gtcacagtgg cagctcaggc acagtttgaa
    12661 aaaggtaagt ggattttgaa cccgtccatc accggtttgg aattttctca tgacacggga
    12721 accgacaaga caagttttgg ccttgaagcc aagggaggtg cttttctact cgacaacatc
    12781 gccttgctgg tgcatgccgg agctgcttgg aataccggag gatctgacct cgatgtctat
    12841 acgctgggtg taggcggacg ttattatttc gacaagattg gcgtgtatct gggtgccgat
    12901 gtcaatgtgg accgttggga ttggggacac gatttggatg ataccaagtt ctctttcggt
    12961 ctggaagccg gttatgcgtt cttcctgacg cgtacggtaa ccattgagcc tgctgcttat
    13021 tggaacatta acgacgaccg ttctaaattt ggtctgaaag taggtttcgg attctatttc
    13081 taatctcatt ttgctactac cacagagttt gtttttgcaa aacatctgtc atgctatcac
    13141 gcggaggggt atattctatt gattacaaat accttaccgc gtgatagata ggcgtgatag
    13201 ataagaatcg ttacacttat ctgtcacgcc catttcgttt ccatttcaat tgtactgcat
    13261 acttctttca ttggcgctat tatcttagtt atcagttctt tcctactgca aagttctgca
    13321 cgctttttgc agtgtcactg catgaggctt gcagtagctc tgcaatacgg ttgcagtcgt
    13381 actgcaatgg gcgtgcagca gcactgcaaa aggaatgcag tgactttgca gtggcgatgc
    13441 agtgtctttt agccgtaatc ttttctattc tcataccgtt attacatgta ttcctaatat
    13501 agtcttatga gattaggggt tctatttttg attatgattg cgaaaatgag tatatttgat
    13561 gctatggact tgaaatacaa aatgctatga acagagtttg ttttctccta ttgctttgtt
    13621 gcctttcatc ctgcaagatg aataagacgg aacgcgtaga aatgcctgaa gattctgtag
    13681 atacggtagg gttagaccga cggttgcagg aaaaatcagt gagcgatagc ctcaagatag
    13741 ggctcgtgga tgacggtgac tgcttgcaaa aacaattgct tgccattcac gacgaactga
    13801 gaaagcggtt ggaaaacaca acctacacac acatccggag gaatgtgacc ggatatgggg
    13861 tggggatgca ttgcatcgat atagatttga tggtgaatac tcccgagcgg cagaaagagt
    13921 tccgggagaa gataatggac tcccccgttt tctgttttca tggtgtagaa gtccccgtca
    13981 tcaacgagag agtaggcagg aatcatattc gtggcatcca tatccgtccc gaatatccgg
    14041 tcttttcaac gaaagctctc catgcgacat tcatcctcag caatcacagc ggcggagatt
    14101 tgacctgcgg cgagcattac tacctgacgt tcgaagacga aaaaggtacc tggcgggaat
    14161 tgccgataaa cgctgccttt tgggacatcg cctatgtgct gcgggatggg gaggaaaggg
    14221 ttatgaaagc ctccctttat ccggatgtgc atcccaacaa gccgggacgc taccgttact
    14281 tttatgagat aaccatcagg aggaaacctg tcttgatgat ggctgagttc agactgacgg
    14341 acaatgagga agaatggaga acggcggaaa agacatctct tcccccttat atttcggatg
    14401 cagggaaggg cgggagccca caattgataa cggaagagcc aatggaagaa ccggtctata
    14461 aagtagtgga agtgatgccc gagtttccgg gaggtatgaa agccttaatg gattttattc
    14521 aaaagaatat ccgttatccg gaagaagtcc gtaagaatgg cattcaagga agagttgctg
    14581 tcagcgtggt gattgacgag aatggtcgtg tgacggaccc cgttattatg cgcagcaggt
    14641 atcctgccct ggatgaggaa gcattacgga ttgtagaatt gatgccacaa tggaaaccgg
    14701 ggatgcagca gggtaaagcc gtgaaggtgg aatttacttt tccggttact tttaaattgg
    14761 agtagtagca cccggtaaga ttaagcacaa agaatctctg tgtctccgtg cctctgtgtt
    14821 ctatttaagg aagcgagggg tgtaatttct cttgcaagaa ttgtcccgta taacttgccg
    14881 cacacttcgc cacttcctcc ggtgtaccgg tagctacgat gtttcctcct ttgtcccctc
    14941 cttcgggccc caggtctatc acatggtccg cacacttcac cacatccaga ttatgttcga
    15001 tgatgacaat gctgtgcccg cggcgtatta gggcatcgaa ggcttcgagc agtttcttga
    15061 tgtcatggaa gtgtagtccg gtggtcggtt catcgaagat gaacatggtc gggtctgctt
    15121 tctcctggct gaggtagaag gcgagtttca cgcgctggtt ctctccaccg gagagggtgg
    15181 aggaggcttg ccccagtttg atatatccca aacctacatc ctgcaagggt tgcagcttct
    15241 tcacaatctt tttctgtccg tgttgcgtaa agaattcgat ggcttggttt acggtcatct
    15301 ccaatacgtc gtagatattc atgtcgtgga acttcacttc cagcgtgtcc gccttgaagc
    15361 gtttgccgtg gcaggattcg cattccagta caaggtctgc catgaattgc atctccaccg
    15421 tgatggtgcc ttcacccttg cattcctcgc aacggccgcc ttcgctgttg aagctgaagt
    15481 atccggcact gtatcccatc tgcttggcaa gcggttggtc cgcccatagt ttacggattt
    15541 catcgtaggc cttgatgtag gtcacggggt tacttctcga tgacttcccg ataggattct
    15601 ggtcaacaaa ctctacattg cgcaggttct gcaagtctcc tccaatggaa gtgaactcgc
    15661 ctggacgttc gttgcattca tccaactctc gtttcagggc gcggtagaag atgtcgcgta
    15721 ccagcgtact cttgcccgaa ccgctgacac cggtgactac ggtcattaca ttcagcggga
    15781 accgtgcctc tacacccttc aggttgtttt cgcgcgcgcc ttttatttct atgtagttgt
    15841 tccacgggcg gcggtgttcc ggcaggggga tggtttcttc gcccagcaga tagcgcacgg
    15901 tatagctgtc actgtctttc tgaaggtctt tcatatctcc ttggtagacg accttccctc
    15961 ccaggcggcc tgcccgggga ccgatgtcga tgatatagtc ggcagcacgg ataatctctt
    16021 catcgtgttc cactaccact accgtattgc ccaactgttg cagctggcgg agcacgtgta
    16081 tcagtttgtc cgtatcgcgg ctatgcaggc cgatgctcgg ttcgtcaaga atatacaggc
    16141 tgcccaccag actacttccc agcgaggtgg cgaggttgat tcgctggctt tcaccgccgg
    16201 agagcgagtt gctgaggcgg ttcagcgtga ggtatcccaa accgacatcc aataggaatt
    16261 ggatgcggct gttgatttct gtcaggatgc ggcgggctat gtcggcttca tgtgggtcta
    16321 gctgcaggtt gtcgaagaag agcttcaact cagtgatggg caaatctacc agttcggaga
    16381 tgttgcgtcc tcccacgcgt acgtagtttg cttcgggctt caggcgggtg ccgtggcatt
    16441 tggggcagag cgtctttccg cggtagcgtg ccagcatcac acggtattgt atcttgtact
    16501 gattttcctg caccatcttg aagaaggcgt tgatgccctc aaagtagggt gtcccttccc
    16561 acagcatccg gcgttgctcg tcggtcagtt cataataggg agtgaagatg gggaagccgg
    16621 ctttctcggc tccgtgtatc accatatccc tccattcgcc catcttttcg ccccgccagc
    16681 atacaacggc tccatcatag acggacaagg agcggtcggg tatcacgaga tgctcgtcga
    16741 tgccgatgac tttcccgaat ccctcgcata cggggcatgc accgatggga gagttga
//
