LOCUS       c00077_gnlPro..        16797 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KLFCFLHC_77.
ACCESSION   c00077_gnlPro..
VERSION     c00077_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 15:05:36
            Original ID  :: gnl|Prokka|KLFCFLHC_77
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 168788
            Orig. end    :: 185585
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16797
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[178788:182346](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13558
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16797
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16797
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(2033..3211)
                     /locus_tag="ctg77_143"
                     /transl_table=11
                     /translation="MNRVCFLLLLCCLSSCKMNKTERVEMPEDSVDTVGLDRRLQEKSV
                     SDSLKIGLVDDGDCLQKQLLAIHDELRKRLENTTYTHIRRNVTGYGVGMHCIDIDLMVN
                     TPERQKEFREKIMDSPVFCFHGVEVPVINERVGRNHIRGIHIRPEYPVFSTKALHATFI
                     LSNHSGGDLTCGEHYYLTFEDEKGTWRELPINAAFWDIAYVLRDGEERVMKASLYPDVH
                     PNKPGRYRYFYEITIRRKPVLMMAEFRLTDNEEEWRTAEKTSLPPYISDAGKGGSPQLI
                     TEEPMEEPVYKVVEVMPEFPGGMKALMDFIQKNIRYPEEVRKNGIQGRVAVSVVIDENG
                     RVTDPVIMRSRYPALDEEALRIVELMPQWKPGMQQGKAVKVEFTFPVTFKLE"
     CDS             3324..3506
                     /locus_tag="ctg77_144"
                     /transl_table=11
                     /translation="MRIEKITAKRHCIATAKSLHSFCSAAARPLQYDCNRIAELLQASC
                     SDTAKSVQNFAVGKN"
     CDS             complement(3715..4203)
                     /locus_tag="ctg77_145"
                     /transl_table=11
                     /translation="MKKLALFVCLLVVTVAAQAQFEKGKWILNPSITGLEFSHDTGTDK
                     TSFGLEAKGGAFLLDNIALLVHAGAAWNTGGSDLDVYTLGVGGRYYFDKIGVYLGADVN
                     VDRWDWGHDLDDTKFSFGLEAGYAFFLTRTVTIEPAAYWNINDDRSKFGLKVGFGFYF"
     CDS             complement(4229..4450)
                     /locus_tag="ctg77_146"
                     /transl_table=11
                     /translation="MKKIKKSTGLTLALLIYVSATAAYFLPRNTEISDTEKYVTVAASY
                     LIVFVLWLVLRKKEALQRKRFEEDNKQH"
     CDS             complement(4450..5880)
                     /locus_tag="ctg77_147"
                     /transl_table=11
                     /translation="MITFTLCLLALIAGYFIYGRFIERVFGPDDRKTPALTKADGVDYI
                     PLPTWKIFMIQFLNIAGLGPIFGAIMGAKFGTASYLWIVLGSIFAGAVHDYLAGMLSLR
                     HDGESLPEIIGRYLGLTTKQVMRGFTVILMILVGAVFVAGPAGLLAKLTPDSLDTTFWI
                     IVVFAYYIFATLLPVDKIIGKIYPLFAVALLFMAVGILVMLYVNHPALPEIWDGLQNTH
                     PDAVALPIFPIMFVSIACGAISGFHATQSPLMARCMTSERHGRPVFYGAMITEGIVALI
                     WAAAATYFFHENGMGETNASIIVDAITKDWLGAVGGVLAILGVIAAPITSGDTAFRSAR
                     LIVADFLGMEQKSMRRRLYICIPMFLVAISLLLYSLRDKDGFDMIWRYFAWANQTLSVF
                     TLWAITVYLVREKKGRYYYVTYFPALFMTAVCTTYICIAPEGFGLGPNYALGIALIAVV
                     LAAIWFNIWYFKTTKKLW"
     CDS             6003..7460
                     /locus_tag="ctg77_148"
                     /transl_table=11
                     /translation="MKRIISILLYMAVLLPLAAQPPKHEVRAAWITAVYGLDWPQTRAT
                     SPEGIRKQQAELIEILDRLKAANFNTVLFQTRTRGDVLYKSAIEPYNSILTGKVGGDPG
                     YDPLAFAIAECHKRGMECHAWMVTIPLGNRKHVAALGKESVTKKKRAICVPYKREYFLN
                     PGHPQTKEYLMSLVREVVERYDVDGIHFDYLRYPENAPRFPDSYDYRKYSKGRSLAQWR
                     RDNLTEIVRYIYKGVKVMKPWVKVSTCPVGKYKDTSRYPSRGWNAFHTVYQDVQGWLGE
                     GIQDQIYPMLYFRGNHFYPFALDWQEQSNGRQIIPGLGIYFLDPSEGNWTLDEIERQMH
                     FIRAHGLAGEAHYRVKYLMDNTQGLYDALEEDFYTAPALQPAMPWIDNVAPTPPAGLTV
                     ETPENGYWKLSWQPATDNDKRNVPMYVIYGSDTYPVDTSNPENILAQRVQGTEYTYAPI
                     RPWTARKYFAVTAIDRCGNESKAIQQQ"
     CDS             complement(7444..8652)
                     /locus_tag="ctg77_149"
                     /transl_table=11
                     /translation="MKLYVFNPDADMALGNNEENYMAPATIRRMAEDLALLPIWYAQPG
                     SGVLASSAYNADYLKQMQQLFRLDVHLVTEPELPDYADVRVMPWGWNPAIRKRMLKGGV
                     LEKNLPTPDALDKYRMKAARSNALAFRALFYSNKIDYTCGDGCCLVEADGGTTAISLDI
                     IGRYKEGCVFKSLWSGSGKGLCWCRHGFTKNVSDWCSRALKENGGFVMEPIFDKVEDFA
                     MEFYSDGRGKLLFVGYSRFVTDDKGAYRGNILTSDGQVEEWIQQYVPFEAFVRIRNMMQ
                     KALETGYATSYTGFLGVDMMVCRQKEGHPYAINPHVEINLRMNMGIVSHVLSDHFIVPG
                     GEGRFSIDCFPTHEALMERHEQDAQSYPLVVKDGRVVSGYLPLVPVTPKSRYRAFVCVT
                     AAE"
     CDS             8781..9959
                     /locus_tag="ctg77_150"
                     /transl_table=11
                     /translation="MEAFYRTHAYLVEHTNAPVRRDLMDEIDWNDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGTDRSCLFINMNNFYFSGHGIVEFAAEFQRRGGKVLLIDQVFKYPEWS
                     KELRMCYDRFPNLKIVFTGSSVMRLKEENMELRDIVKSYNLRGFSFREYLNLQTGMKFH
                     AYPLEEILSNHEQIAKGILSKVRPLDYIQDYMHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLANDIQTSRATVMNYIKYLADAR
                     LINMVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANTMWKDHKVNKGD
                     KNISFMVDEVMPFNICPEGTKIKNNPGVTYVLHKAEIGRGNQIPLWLFGFLY"
     CDS             10001..13558
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg77_151"
                     /sec_met_domain="PFOR_II (E-value: 2.8e-18, bitscore: 59.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.2e-81, bitscore: 267.0,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 9.3e-31, bitscore: 100.5,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-11, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.1e-11, bitscore: 38.8,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 6.4e-07, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00035, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 3.8e-25, bitscore: 80.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KARVPFMNFFDGFRTSHEIQKIEMLENEDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGLVAVHLYRPFSAKHFLAAVPKTAKKIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILAVYKNLAMPMPKNHFTIGIVDD
                     VTFTSLPQEEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNITVYYINATQIAQEIGLGNRTNTILQSAFFRITGVIPV
                     DLAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKQLTVDPAWANLADDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWEQGTAKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGANFTQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADV
                     CPGNPKKGGKALTMKHLESQLPEAANWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTKNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKAMEDAIAAEGTPAEYKEVFQAWIENMYDADKSKE
                     LAEKIIPMVEAAKDKCDSCKTIASLSQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQAEEEKAVKCGYWHLWR
                     YNPALEAEGKNPFTLDSKEPDWSGFQDFLKGEVRYASVMKQYPQEADELFKAAEENAKW
                     RYNSYKRLSKENWGAEVTE"
     CDS             13649..13837
                     /locus_tag="ctg77_152"
                     /transl_table=11
                     /translation="MIGFIIWIIGVVLCVKAVLEIMKWPVDGVKKLLVAIIILLTSWIG
                     ICVYYFWGRENLPQILK"
     CDS             complement(13900..16665)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg77_153"
                     /sec_met_domain="Peripla_BP_1 (E-value: 5.6e-16, bitscore:
                     52.0, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKMRQHNLRILFFLLVLWGVAVACSRREARFRIGVSQCSEDEWRR
                     QMNSEILREAHFYEDVEVDIRTAVDDNDRQAKDIRELIAEGVDLLIVAPNEATPITPVV
                     EEAYNRGIPVIVVDRKILSDKYTAYVGADNYEIGKAVGEYVANVLHGQGDVVEISGLVG
                     STPAVDRHQGFVKAISAYPGIRLLAVEDGAWLQLKAGEKMDTLLSRFPHIDLVYAQNDR
                     MAAGAYAAAAREGREKDMRFIGIDALSGKDYGVEKVLAGELDATFIYPTGGDRVMQIAM
                     DILNKRDFPRETILGTSVVDRDNALIMKMQTAHIGTLDGKIETLNGKINQYLASYATQQ
                     VVLYGSLSALLLLVGLLVAVYLSLRAKNRLNRELSMQKKKLEEQKTQLIQQKELLEVQK
                     SQLEQLSHELEEATHAKLVFFTNISHDFRTPLTLIADPIEQLLANRTLDGQPRQLLELM
                     KKNVHILLRLVNQILDFRKVENGRMELHLEPFDLLDSFRGWNDSFRMALLKKHIAFSFE
                     ASPDTDFRMMADAEKMERIYFNLFSNAVKYTPENGKIAIRLSMTEQNYSLSVFNSGSYI
                     SSTDVEAIFERFYQVDGHQAGTGIGLALVRAFVEMHGGNIAAHSDDKGTTFTVTFPKQD
                     VLQYHPTIVTLPAEEKDVSSTLIDTEVKACEEVVEADCPTVLVIDDNADIRNYVKSLLS
                     NEFRVLDAADGTEGIRLAMKYVPDVIISDVMMPGMDGVECCRRLKGELQTCHIPVILLT
                     ACSLDEQRIQGYDGGADSYISKPFNSQLLLSRVRNLIANRRQLRQFFGDNQTIEKEAIS
                     DLDKGFVSRFKSLVEERMKDAELNVEDLGRNMGMSRVQLYRKLKSLTNYSPNELLRQMR
                     LKKAASLLASSDMTVAEIAYEVGFSSPSYFTKCYKEQFGESPTEFLKRRG"
ORIGIN
        1 tcaactctcc catcggtgca tgccccgtat gcgagggatt cgggaaagtc atcggcatcg
       61 acgagcatct cgtgataccc gaccgctcct tgtccgtcta tgatggagcc gttgtatgct
      121 ggcggggcga aaagatgggc gaatggaggg atatggtgat acacggagcc gagaaagccg
      181 gcttccccat cttcactccc tattatgaac tgaccgacga gcaacgccgg atgctgtggg
      241 aagggacacc ctactttgag ggcatcaacg ccttcttcaa gatggtgcag gaaaatcagt
      301 acaagataca ataccgtgtg atgctggcac gctaccgcgg aaagacgctc tgccccaaat
      361 gccacggcac ccgcctgaag cccgaagcaa actacgtacg cgtgggagga cgcaacatct
      421 ccgaactggt agatttgccc atcactgagt tgaagctctt cttcgacaac ctgcagctag
      481 acccacatga agccgacata gcccgccgca tcctgacaga aatcaacagc cgcatccaat
      541 tcctattgga tgtcggtttg ggatacctca cgctgaaccg cctcagcaac tcgctctccg
      601 gcggtgaaag ccagcgaatc aacctcgcca cctcgctggg aagtagtctg gtgggcagcc
      661 tgtatattct tgacgaaccg agcatcggcc tgcatagccg cgatacggac aaactgatac
      721 acgtgctccg ccagctgcaa cagttgggca atacggtagt ggtagtggaa cacgatgaag
      781 agattatccg tgctgccgac tatatcatcg acatcggtcc ccgggcaggc cgcctgggag
      841 ggaaggtcgt ctaccaagga gatatgaaag accttcagaa agacagtgac agctataccg
      901 tgcgctatct gctgggcgaa gaaaccatcc ccctgccgga acaccgccgc ccgtggaaca
      961 actacataga aataaaaggc gcgcgcgaaa acaacctgaa gggtgtagag gcacggttcc
     1021 cgctgaatgt aatgaccgta gtcaccggtg tcagcggttc gggcaagagt acgctggtac
     1081 gcgacatctt ctaccgcgcc ctgaaacgag agttggatga atgcaacgaa cgtccaggcg
     1141 agttcacttc cattggagga gacttgcaga acctgcgcaa tgtagagttt gttgaccaga
     1201 atcctatcgg gaagtcatcg agaagtaacc ccgtgaccta catcaaggcc tacgatgaaa
     1261 tccgtaaact atgggcggac caaccgcttg ccaagcagat gggatacagt gccggatact
     1321 tcagcttcaa cagcgaaggc ggccgttgcg aggaatgcaa gggtgaaggc accatcacgg
     1381 tggagatgca attcatggca gaccttgtac tggaatgcga atcctgccac ggcaaacgct
     1441 tcaaggcgga cacgctggaa gtgaagttcc acgacatgaa tatctacgac gtattggaga
     1501 tgaccgtaaa ccaagccatc gaattcttta cgcaacacgg acagaaaaag attgtgaaga
     1561 agctgcaacc cttgcaggat gtaggtttgg gatatatcaa actggggcaa gcctcctcca
     1621 ccctctccgg tggagagaac cagcgcgtga aactcgcctt ctacctcagc caggagaaag
     1681 cagacccgac catgttcatc ttcgatgaac cgaccaccgg actacacttc catgacatca
     1741 agaaactgct cgaagccttc gatgccctaa tacgccgcgg gcacagcatt gtcatcatcg
     1801 aacataatct ggatgtggtg aagtgtgcgg accatgtgat agacctgggg cccgaaggag
     1861 gggacaaagg aggaaacatc gtagctaccg gtacaccgga ggaagtggcg aagtgtgcgg
     1921 caagttatac gggacaattc ttgcaagaga aattacaccc ctcgcttcct taaatagaac
     1981 acagaggcac ggagacacag agattctttg tgcttaatct taccgggtgc tactactcca
     2041 atttaaaagt aaccggaaaa gtaaattcca ccttcacggc tttaccctgc tgcatccccg
     2101 gtttccattg tggcatcaat tctacaatcc gtaatgcttc ctcatccagg gcaggatacc
     2161 tgctgcgcat aataacgggg tccgtcacac gaccattctc gtcaatcacc acgctgacag
     2221 caactcttcc ttgaatgcca ttcttacgga cttcttccgg ataacggata ttcttttgaa
     2281 taaaatccat taaggctttc atacctcccg gaaactcggg catcacttcc actactttat
     2341 agaccggttc ttccattggc tcttccgtta tcaattgtgg gctcccgccc ttccctgcat
     2401 ccgaaatata agggggaaga gatgtctttt ccgccgttct ccattcttcc tcattgtccg
     2461 tcagtctgaa ctcagccatc atcaagacag gtttcctcct gatggttatc tcataaaagt
     2521 aacggtagcg tcccggcttg ttgggatgca catccggata aagggaggct ttcataaccc
     2581 tttcctcccc atcccgcagc acataggcga tgtcccaaaa ggcagcgttt atcggcaatt
     2641 cccgccaggt acctttttcg tcttcgaacg tcaggtagta atgctcgccg caggtcaaat
     2701 ctccgccgct gtgattgctg aggatgaatg tcgcatggag agctttcgtt gaaaagaccg
     2761 gatattcggg acggatatgg atgccacgaa tatgattcct gcctactctc tcgttgatga
     2821 cggggacttc tacaccatga aaacagaaaa cgggggagtc cattatcttc tcccggaact
     2881 ctttctgccg ctcgggagta ttcaccatca aatctatatc gatgcaatgc atccccaccc
     2941 catatccggt cacattcctc cggatgtgtg tgtaggttgt gttttccaac cgctttctca
     3001 gttcgtcgtg aatggcaagc aattgttttt gcaagcagtc accgtcatcc acgagcccta
     3061 tcttgaggct atcgctcact gatttttcct gcaaccgtcg gtctaaccct accgtatcta
     3121 cagaatcttc aggcatttct acgcgttccg tcttattcat cttgcaggat gaaaggcaac
     3181 aaagcaatag gagaaaacaa actctgttca tagcattttg tatttcaagt ccatagcatc
     3241 aaatatactc attttcgcaa tcataatcaa aaatagaacc cctaatctca taagactata
     3301 ttaggaatac atgtaataac ggtatgagaa tagaaaagat tacggctaaa agacactgca
     3361 tcgccactgc aaagtcactg cattcctttt gcagtgctgc tgcacgccca ttgcagtacg
     3421 actgcaaccg tattgcagag ctactgcaag cctcatgcag tgacactgca aaaagcgtgc
     3481 agaactttgc agtaggaaag aactgataac taagataata gcgccaatga aagaagtatg
     3541 cagtacaatt gaaatggaaa cgaaatgggc gtgacagata agtgtaacga ttcttatcta
     3601 tcacgcctat ctatcacgcg gtaaggtatt tgtaatcaat agaatatacc cctccgcgtg
     3661 atagcatgac agatgttttg caaaaacaaa ctctgtggta gtagcaaaat gagattagaa
     3721 atagaatccg aaacctactt tcagaccaaa tttagaacgg tcgtcgttaa tgttccaata
     3781 agcagcaggc tcaatggtta ccgtacgcgt caggaagaac gcataaccgg cttccagacc
     3841 gaaagagaac ttggtatcat ccaaatcgtg tccccaatcc caacggtcca cattgacatc
     3901 ggcacccaga tacacgccaa tcttgtcgaa ataataacgt ccgcctacac ccagcgtata
     3961 gacatcgagg tcagatcctc cggtattcca agcagctccg gcatgcacca gcaaggcgat
     4021 gttgtcgagt agaaaagcac ctcccttggc ttcaaggcca aaacttgtct tgtcggttcc
     4081 cgtgtcatga gaaaattcca aaccggtgat ggacgggttc aaaatccact tacctttttc
     4141 aaactgtgcc tgagctgcca ctgtgacaac aagcaagcaa acgaataatg ccagtttttt
     4201 catcttgttc tgttttttga gtgaataatc aatgttgttt attgtcttct tcgaatcgct
     4261 tgcgttgcag cgcctccttc ttgcgaagca ccagccacag cacaaataca atgaggtacg
     4321 aagcagctac ggtgacatac ttctcagtat cgctgatttc cgtattgcgg ggaaggaaat
     4381 aagcggcagt agcagaaacg taaataagca gggccaacgt gagcccggta gatttcttga
     4441 ttttcttcat taccaaagtt ttttagtcgt cttaaaatac caaatattaa accaaatagc
     4501 agccagcaca acagctatca aggctatgcc cagcgcataa ttcggaccga gcccgaaacc
     4561 ttcgggagca atgcagatgt aagtggtaca cacagccgtc atgaataatg ccgggaaata
     4621 ggtgacgtaa taataacgtc ctttcttctc gcgtaccaga tagaccgtaa tggcccacaa
     4681 cgtaaagacg gacagagtct gattggccca ggcaaaataa cgccaaatca tatcaaatcc
     4741 atccttgtcc cgcaggctgt aaagcaacaa gctaatggct accaggaaca tcgggatgca
     4801 tatatataaa cggcgacgca tggatttttg ttccattccc aagaaatccg ccacaatgag
     4861 gcgcgctgaa cggaaagccg tgtcgccact ggtaataggc gcggcaataa cacccagaat
     4921 ggccaatacg ccacctacgg cacccagcca gtcttttgta atggcgtcta caatgataga
     4981 ggcattcgtc tcccccatcc cgttctcgtg gaagaaataa gtggcggcgg cagcccatat
     5041 cagggctaca atgccttcgg ttatcattgc cccatagaaa acggggcgtc cgtggcgctc
     5101 gcttgtcatg caacgtgcca tcagcggact ctgcgtggca tggaagccac tgatggcacc
     5161 gcaggcaatg ctgacgaaca tgatggggaa gatgggcaat gcaaccgcat cgggatgcgt
     5221 gttctgcaat ccgtcccata tctccggcaa tgcaggatgg ttgacgtaaa gcattaccag
     5281 aataccgacc gccatgaaca gcagggcaac ggcgaacagc gggtatatct taccgataat
     5341 cttatctacc ggcagcaaag tggcaaagat ataataagcg aaaacaacaa taatccagaa
     5401 ggtggtatcc aagctgtcgg gggtcaactt ggcaagcagt ccggccggcc ctgccacaaa
     5461 gacagctccc accaatatca tcaggatgac ggtaaagccg cgcatcacct gcttggtggt
     5521 cagccccaga tagcgtccga tgatttccgg caggctttcc ccgtcatgcc gcaaggagag
     5581 cataccggca agatagtcgt gcactgcacc ggcaaagata ctgccaagta caatccacag
     5641 ataggatgcc gtaccgaact tggctcccat gatggcaccg aagataggtc ccaacccggc
     5701 aatattgaga aactgtatca taaagatttt ccaagtaggc agtggaatgt aatccacacc
     5761 atcggctttg gtaagggcgg gtgttttgcg gtcatcggga ccaaagacgc gttctatgaa
     5821 gcgtccgtag ataaaatagc cggctatcaa cgccagcagg caaagcgtaa atgtaatcat
     5881 ggcgtgttaa tatctttaat gtatgcaaat gtaacagttt ccaagtaaac agcacaaaat
     5941 aatcgggtgt tttgcttatc ttcgccgaga aatatgacag aaataaagaa gaaaagagaa
     6001 aaatgaaacg aattatttcc attttactat atatggccgt cttgctgcca ctggctgcgc
     6061 aaccgcccaa gcatgaagtg cgtgccgcct ggataactgc cgtctatggc ctggactggc
     6121 cgcagacacg cgccacttcg cccgaaggca tccgcaagca acaggccgaa ctgattgaaa
     6181 tattggacag actgaaagcc gccaatttca acacagtact gttccagacc cgtacacggg
     6241 gagatgtcct ctacaaatca gccatcgagc cctacaactc catactgacc ggaaaggtgg
     6301 gcggcgaccc cggctacgat ccgctggctt ttgccatagc cgaatgccac aagcgcggta
     6361 tggagtgcca tgcctggatg gtgaccatcc ctctgggcaa ccgcaagcat gtagccgccc
     6421 tcggtaaaga gtccgtcacc aaaaagaaac gcgccatctg cgtaccctac aaacgcgaat
     6481 acttcctgaa tcccggacat ccgcaaacca aagagtacct gatgagtctt gtccgcgaag
     6541 tggtggaacg ctacgatgta gacgggatac acttcgacta cctgcgctat ccggaaaacg
     6601 ccccccgttt tcccgacagc tacgactacc gcaaatacag caaaggacgc agccttgccc
     6661 aatggcgcag agacaacctg acggaaatag tacgctatat atataaaggt gtaaaagtca
     6721 tgaaaccctg ggtaaaggtc agcacctgcc cggtaggaaa atacaaagac acttcccgct
     6781 acccctcccg tggctggaat gccttccaca ccgtctatca agacgtgcag ggttggctgg
     6841 gcgagggcat ccaggaccag atttatccga tgctctattt ccgcggcaat catttctatc
     6901 cctttgccct cgactggcag gaacaaagta acggacgcca aatcattccc ggtctgggca
     6961 tctacttcct cgaccccagc gaagggaact ggacgctgga cgagattgaa cggcagatgc
     7021 actttatccg cgcccacggt ctggcgggcg aggcacacta ccgcgtgaag tatctgatgg
     7081 acaatacgca agggctttat gatgcgctgg aagaagactt ctataccgcc ccggccctgc
     7141 agcccgccat gccgtggata gacaatgtag ctcctacacc tcccgccgga ctcacggtgg
     7201 aaacaccgga aaacggctat tggaaactaa gctggcaacc cgccacggat aatgacaagc
     7261 ggaatgttcc gatgtatgta atctacggtt cggacaccta tcccgtagat acctccaatc
     7321 cggagaatat cctggcacaa cgagtacaag gcacggaata tacctatgcc cccatccgcc
     7381 cgtggactgc ccgaaaatat tttgccgtga cagccataga ccgttgcgga aacgaaagca
     7441 aagctattca gcagcagtga cacagacaaa agcccggtaa cggctcttcg gagtgaccgg
     7501 aaccagaggc agatagccgg aaacaaccct gccgtccttc accaccagcg gataactttg
     7561 cgcatcctgc tcatgccgct ccatcaaagc ttcatgggtc ggaaagcaat cgatggagaa
     7621 acgtccctcc ccaccgggga caatgaaatg atcactaagc acatgggaaa cgattcccat
     7681 attcatccgt agatttattt cgacatgggg gttgatggca tacggatgcc cttccttctg
     7741 acggcagacc atcatgtcca cacccaaaaa acccgtataa gatgtagcat aacccgtttc
     7801 caatgccttc tgcatcatat tgcgtatgcg cacaaatgct tcaaagggca catattgctg
     7861 aatccattcc tccacttgcc catctgaagt aaggatatta ccacgataag cccccttgtc
     7921 atccgtaaca aaacgggaat agccgacaaa aagaagcttt ccccggccat ccgaataaaa
     7981 ttccatggca aaatcttcca ccttatcaaa tataggctcc atcacaaaac ctccattttc
     8041 tttcagcgcc ctactacacc aatcggaaac atttttcgta aagccatgac ggcaccaaca
     8101 caatcccttc ccacttcccg accaaagtga tttaaacaca catccctctt tgtaacgacc
     8161 aataatatcc agagagatag ccgtagttcc accatcagcc tccaccaagc aacaaccgtc
     8221 accacaagta taatctattt tattggaata gaaaagtgca cgaaaagcca aagcgttact
     8281 acgggcagcc ttcatacgat atttatccaa agcatccggc gtaggaagat ttttttccag
     8341 aacaccgcct ttcaacatcc gtttacggat agcggggttc catccccaag gcattacccg
     8401 cacatcagca taatcgggca gctccggctc tgtcaccaaa tgcacatcca gccggaacaa
     8461 ctgttgcatc tgtttcagat aatctgcatt ataggcggaa gaggccagta ccccactacc
     8521 cggctgggca taccaaatcg gcaacaaagc caagtcttca gccatacggc ggatggtagc
     8581 gggcgccata taattttctt cattatttcc caatgccata tctgcatcag gattgaacac
     8641 ataaagtttc atctttcaaa tgttaaccaa ttactcacgt tttgtatgag agtgcaaagt
     8701 tatataatat tttgccatct ctactttgca aatctataaa aaagccgtat atttgtcgcc
     8761 cgataaaccg aatttaaagc atggaagcat tttaccgtac acacgcttat ctcgtagagc
     8821 ataccaatgc ccccgtacgc cgcgacctaa tggacgaaat agactggaat gaccgtctta
     8881 tcggtatcaa aggcacaaga ggcgtaggta agactacttt cttgctgcaa tatgccaaag
     8941 agaaattcgg cacagaccgc tcctgcctct tcatcaacat gaacaacttc tacttctccg
     9001 gacatggcat cgtggagttc gccgccgaat tccagcgccg cggaggaaaa gtgctgttga
     9061 tagaccaggt attcaagtac ccggaatgga gcaaggaact gcgtatgtgc tacgaccgct
     9121 tccccaacct gaaaatcgtg ttcaccggct cgtccgtgat gcgtctgaaa gaggagaata
     9181 tggagttgcg cgacatcgtg aagagctaca acctgcgcgg cttctccttc cgcgaatacc
     9241 tgaacctgca gacgggcatg aagttccatg cctatccgtt ggaagaaatc ctgagcaacc
     9301 acgaacagat agccaaaggc atcctctcca aagtacgtcc attggactac atacaagact
     9361 atatgcacca cggcttctac cctttcttcc ttgaaaagcg taacttttcg gagaatctgc
     9421 tcaagacgat gaacatgatg gtggaagtgg atatcctgct catcaaacaa attgagctga
     9481 aatacctttc gaagataaag aaattactat atttgttggc cgtggacggg ccgaaagcgc
     9541 cgaatgtcag ccaactggca aacgacatac agacctcccg cgccacagta atgaattaca
     9601 tcaagtatct ggcagacgca cgactcatca atatggtcta tccgaaggga gaagaattcc
     9661 ccaagaagcc gtcgaagata atgatgcaca attcaaatct gatgtattcc atctatcccg
     9721 tcaaggtgga agagcaagac gtactggaca ctttctttgc caacacaatg tggaaggacc
     9781 acaaggtgaa caagggcgac aagaacatct cgttcatggt agatgaggtg atgcctttca
     9841 atatttgtcc ggaaggaaca aagataaaga ataatccggg agttacttat gtactgcata
     9901 aggcagaaat aggccgaggc aaccaaatac ctctctggtt attcggtttc ttgtattaag
     9961 agagagattt ttttacttaa ataaataatt caatttagtt atgactaaac agaagaaatt
    10021 cattacttgt gatggtaacc aggctgctgc acatatctcg tatatgttct ccgaagtagc
    10081 tgccatctac cccatcaccc cctcttctac gatggctgaa tacgtagacg aatgggctgc
    10141 cgcaggtcgc aagaacatct tcggcgaaac agtattggta caggaaatgc agtcagaagg
    10201 tggtgctgca ggtgccgtcc acggctctct gcaagccggt gcgctgacta ctacttacac
    10261 agcttcacaa ggtctgttgc tgatgatccc gaacatgtac aagattgccg gtgaattcct
    10321 gccttgtgta ttccacgtat cagcacgtac attggcaagc catgcactgt gtatcttcgg
    10381 tgaccaccag gacgttatgt ctgcacgcca gactggtttt gccatgttgg ccgaaggttc
    10441 tgtacaagaa gttatggact tggcaggtgt tgcccaccta gccaccatca aggcccgtgt
    10501 tccgtttatg aacttcttcg acggcttccg tacttctcac gaaatccaga agattgaaat
    10561 gttggagaac gaagacctcg ctccgcttat cgaccaggaa gctttggctg aattccgcgc
    10621 acgtgcattg aacccgatga acccggttgc ccgtggtatg gccgaaaatc ctgaccactt
    10681 cttccaacac cgtgaatctt gcaacaacta ctatgaagca gttccggcta tcgttgagga
    10741 atacatgaac gagatttcca aaatcacagg ccgcaagtat ggtttgttcg attactacgg
    10801 tgcagaagat gcagaacgcg ttatcatcgc catgggttct gtaacggaag ctgcccgcga
    10861 agctatcgac cacctcgttg ccaatggcga aaaggttggt ttggttgccg ttcacttgta
    10921 tcgtccgttc tctgccaagc acttccttgc cgccgttccc aagactgcca agaagattgc
    10981 cgtactggac cgtacgaaag aaccgggtgc taacggcgaa ccgttgtacc tcgacgtaaa
    11041 agactgcttc tacggtgcag agaatgctcc ggttatcgta ggcggccgtt acggtttggg
    11101 atccaaggac actactcccg cgcaaatcct cgccgtttac aagaacctgg ctatgccgat
    11161 gccgaagaac cacttcacta tcggtatcgt agacgacgtt accttcactt ctctgcccca
    11221 ggaagaagaa atcgcattgg gcggcgaagg catgttcgaa gccaaattct acggtttggg
    11281 cgctgatggt acagtaggtg ccaacaagaa ctctgtgaag attatcggtg acaataccga
    11341 caagcactgc caggcttatt tctcttacga ctccaagaaa tcaggcggtt tcacctgctc
    11401 gcacctgcgt ttcggtgata ctcctatccg ctctacatac ctggtaaaca cgcctaactt
    11461 cgtggcttgc cacgttcaag cttacctgca catgtacgac gtaacccgcg gcttgcgtaa
    11521 gaacggctct ttcttgctga acaccatctg ggaaggcgaa gagcttgcca agaacctgcc
    11581 caacaaggtg aagaagtact ttgcacagaa caatatcact gtttactata tcaacgctac
    11641 tcagattgca caagaaatcg gtttgggcaa ccgtaccaac accatcctgc aatccgcatt
    11701 cttccgtatc accggcgtta ttccggttga cctggctgta gaacagatga agaaattcat
    11761 cgttaagtct tacggcaaga agggtgaaga cgttgtcaac aagaactacg cagcagttga
    11821 ccgtggcggc gaatacaagc aactgaccgt tgacccggct tgggccaatc tggcagacga
    11881 cgccaaggct gaaaacaacg atcctgcatt catcaacgaa gtggttcgtc ctatcaacgc
    11941 acaagacggt gacttattgc cggtatccgc tttcaagggt attgaagacg gtacttggga
    12001 acaaggcact gccaaatatg agaaacgtgg tgtagccgca ttcgttcccg aatggaacgc
    12061 tgagaactgt atccagtgta acaagtgtgc ttacgtttgt cctcacgctt ccatccgtcc
    12121 gttcgtactc gatgctgaag agcagaaggg tgccaacttc actcaactga aggctgtagg
    12181 taaagcattc gacggtatga cattccgtat tcaggtagac gttctcgact gtctgggttg
    12241 tggcaactgt gccgatgtct gtccgggcaa cccgaagaag ggtggcaaag ctctgactat
    12301 gaagcacctc gaaagccaat tgccggaagc tgccaactgg acttactgtg ctgaaaacgt
    12361 gaagagcaaa caacacttgg ttgacatcaa ggccaacgtg aagaactctc agttcgccac
    12421 tccgttgttc gagttctcag gtgcttgctc cggttgtggt gaaactccgt atgtgaagct
    12481 gatttcccag ttgttcggtg accgcgaaat ggtagccaac gcaacaggat gttcttccat
    12541 ctactccggt tcagtacctt ctactcctta taccaagaac gaaaagggtc acggtcctgc
    12601 ttgggctaac tcattgttcg aggacttctg cgaattcggt ctgggtatgg agcttgccaa
    12661 cgaaaagatg cgcgcacgta tcgtgaaggc tatggaagat gccatcgcag cagaaggaac
    12721 tccggctgaa tacaaagaag tattccaggc ttggattgaa aacatgtacg atgcagacaa
    12781 gagcaaggaa ctggctgaaa agattattcc gatggtagaa gctgccaaag acaagtgcga
    12841 cagctgcaag actatcgcca gtctgtctca atacctggta aaacgcagcc agtggattat
    12901 cggtggcgac ggtgcctctt acgacatcgg ttacggtggt ctcgaccatg taatcgcaag
    12961 cggtaaggat gtcaacatcc tcgtactgga tactgaggtt tactccaaca caggcggtca
    13021 gtcttccaag gctaccccgg taggcgctat cgccaagttt gccgctgccg gtaagcgtgt
    13081 acgcaagaaa gacctcggtc tgatggctac tacttacggt tacgtatacg ttgcccaaat
    13141 cgctatgggt gccgaccagg ctcagaccct gaaggctatc cgtgaagcag aagcatatcc
    13201 cggtccgtca ctcatcatcg cttacgctcc gtgtatcaac cacggtctga aggcaggtat
    13261 gggtaagagc caggcagagg aagaaaaggc cgttaagtgc ggttactggc acttgtggcg
    13321 ttacaacccg gctctggagg ctgaaggcaa gaatccgttc acgctggata gcaaggaacc
    13381 ggattggagc ggattccaag acttcctgaa gggtgaagtt cgttacgcat ccgtaatgaa
    13441 gcaatatccg caggaggccg acgagctgtt caaggctgct gaagaaaacg ctaaatggcg
    13501 ttacaacagc tacaagcgtc tttccaaaga aaattggggc gctgaagtta cagagtaatt
    13561 ccgattacta aataaagaat agaggctgct cctgaataag gcgtagtctc tatttgtttt
    13621 taattaacaa tactaaatat cacaggttat gattggattt atcatttgga ttatcggtgt
    13681 ggttctgtgt gtcaaagccg tacttgaaat catgaagtgg ccggtagacg gcgtgaagaa
    13741 actattagtt gcaattatca tcctgctcac aagctggatt ggaatctgtg tttactactt
    13801 ctggggaagg gaaaacctgc ctcaaatact gaaataagtt ccagtatcat ttacagaagt
    13861 aaacagacgt gtattaagaa caagggggat agacaacagc tatccccttc ttttcagaaa
    13921 ctcggtagga ctctccccaa actgttcctt atagcatttc gtgaaatagg aaggtgacga
    13981 aaagcccact tcataggcaa tctccgctac cgtcatgtca gaggaggcaa gcagtgaggc
    14041 agcctttttc aacctcatct ggcgcagcag ctcattcggc gaatagttgg tcagcgattt
    14101 cagcttacgg taaagctgca cacggctcat acccatattc cgtcccaaat cctccacatt
    14161 gagttccgca tctttcatcc tctcctcgac aagcgatttg aagcgggaga cgaaaccctt
    14221 atccaaatca ctgatggctt ccttctcgat agtctggtta tctccgaaga actgcctcaa
    14281 ctgacggcgg tttgcaataa gattgcggac acgagacaag agcaactgcg aattgaatgg
    14341 tttggaaata taagaatcgg caccgccatc atagccctgg atacgctgtt cgtccagcga
    14401 gcaggccgtc agcagaatca ccgggatatg gcatgtctgc aactccccct tcaagcggcg
    14461 gcagcattcc acaccatcca taccgggcat cattacatcg gagataatca catccggcac
    14521 atacttcatg gccagccgga taccctctgt cccgtccgca gcatccaata cacggaactc
    14581 gttcgacaga agagacttca catagttgcg aatatccgca ttatcgtcaa ttaccagcac
    14641 agtaggacaa tcagcctcaa ccacctcttc gcatgccttc acttccgtat ctatcagggt
    14701 ggacgacacg tccttctctt cggcaggcaa cgtcactatg gtgggatggt actgcaaaac
    14761 atcctgcttc gggaaagtga cggtgaaggt agtaccctta tcatcactgt gtgccgcaat
    14821 gttgccacca tgcatctcta caaaagcacg taccagcgca aggccgatac cggtacctgc
    14881 ctgatgtccg tccacttgat aaaaacgctc gaagatagct tccacatcgg tcgaagaaat
    14941 gtaactgccg gaattgaaaa cagacaagct atagttctgc tctgtcattg acaagcgtat
    15001 agctatcttc ccgttctccg gcgtatactt cacggcattg gagaagagat tgaagtaaat
    15061 gcgctccatc ttctccgcat ccgccatcat ccggaagtcc gtatcgggag atgcctcaaa
    15121 gctgaaagca atatgtttct tcagcaacgc catgcggaaa gagtcgttcc agccccggaa
    15181 gctgtcgagc aaatcaaaag gttcgagatg gagctccatg cgcccgttct ccaccttccg
    15241 gaaatcaagt atctggttga ccaggcgaag caggatatgc acattctttt tcatcagctc
    15301 gaggagctgg cgcggctgtc cgtcgagggt gcggttggca agaagctgct ctatgggatc
    15361 ggctatcagc gtcagcggag tacggaaatc gtgtgaaata ttcgtgaaga acaccagctt
    15421 ggcgtgcgta gcctcctcca gttcatggga aagctgttcc aactgcgact tctgcacttc
    15481 caacagttcc ttctgctgta tcaactgagt tttctgttct tccagtttct ttttctgcat
    15541 ggacagctca cggttcaacc ggttcttggc acgcaaggag aggtagacag ccaccaacaa
    15601 accgaccagc aacaataggg cagacagact gccgtacaag acaacctgct gcgtggcata
    15661 actggccaaa tactggttta tctttccgtt cagggtttct atctttccat ccagggtgcc
    15721 gatgtgggcg gtctgcatct tcatgatgag agcattgtcg cggtcgacga cggaagtgcc
    15781 caggatagtt tcacggggga aatcacgctt gttcaggata tccatggcaa tctgcatcac
    15841 gcggtcgcca ccggtaggat atataaacgt ggcatccagt tcgccggcaa gcactttctc
    15901 cactccatag tctttgccgg acagggcgtc tatgccgatg aaccgcatat ccttttcccg
    15961 cccctctcgg gcagcggcag cataggctcc ggccgccata cggtcattct gcgcatacac
    16021 caggtcgata tgcggaaagc ggctcagcag agtatccatt ttctctccgg ccttgagttg
    16081 caaccaggca ccgtcttcaa cggccagcaa ccggataccg ggataagcgg atatagcctt
    16141 cacaaatcct tgatgacggt ctacggcagg tgtggagccc accaaacctg agatttccac
    16201 cacatctccc tgcccatgca gcacattggc cacatactct cccacagctt tccctatctc
    16261 gtagttgtct gcaccgacgt aggccgtgta tttgtccgaa aggattttac ggtccactac
    16321 aatcaccgga atgccccggt tgtatgcctc ctccacaacc ggagttatcg gagtggcttc
    16381 attaggggcc acaatcagca gatccacccc ttcggctatc agctcacgaa tgtcttttgc
    16441 ctgacggtca ttatcgtcga cagcagtacg gatgtccacc tccacatcct cgtagaaatg
    16501 ggcttcacgg agtatctcac tgttcatctg gcgccgccat tcatcctcgc tacattggga
    16561 aacgccgata cggaaacgtg cctcgcgccg ggagcaggca accgccactc cccaaagcac
    16621 gagcaaaaag aataaaatcc gaaggttatg ctgtctcatc ttcactttcc tctgatttaa
    16681 gattgcagat gagcaaagat aacgaaaaat gtgaaaagaa ccttaattcc gcaacactat
    16741 tataaattaa actttttaag tacctgagca acaaaaagtt gctcaggatt ttgccat
//
