LOCUS       c00012_gnlPro..        14680 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NPABEPKC_12.
ACCESSION   c00012_gnlPro..
VERSION     c00012_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 17:40:46
            Original ID  :: gnl|Prokka|NPABEPKC_12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14680
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14680
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1209:4680]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1210..4680
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14680
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14680
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             208..1071
                     /locus_tag="ctg12_1"
                     /transl_table=11
                     /translation="MPNSSACRGKKQCAQCPKAVDNAIIYASHLRGFHLPARKCEENII
                     IFLLKGEVLVNSKEYAGTVLHAGEFILQAIGSKYEILAMTDVECVCYRFSKPEFFCEDR
                     YNHIMKEVTPPLIFYPLTITPELQLFLESSKAYLSEEKICREMLCFKRKELAFILGNYY
                     SDYELSMLIHPLAQYTNSFHYFVLQNHAKVKTVEELAQLGGYTVATFRRIFNSVFHQPV
                     YEWMMERRKESVVYELRYTDASISEICYKYGFESLPHFSNFCKKNFGASPRSLRAGNLS
                     EVNGMS"
     CDS             complement(1210..1965)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_2"
                     /sec_met_domain="Fer4_7 (E-value: 4.2e-12, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.3e-25, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.6e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(1999..3945)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 201; E-value:
                     1.2e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 9.4e-62, bitscore:
                     201.0, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.9e-37,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNNIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMEDVVLIDGRARGIIAKNLVTGKLERFAAHA
                     VVIATGGYGNAYFLSTNAMACNCSAAMACYRKGAWFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKLEDAKKLQEGTLQGKDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDKGYGVNNTGLAVFLDFSEAINRLGKDVVAQRYGNLFDMYEEITDVSPYE
                     NPMMIYPAIHYTMGGIWVDYELMTSIKGLFAIGECNFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQITVPRFSTDLPEFAAAEKAVQDKIDWMMNIKGKKSVDSIHKELGHI
                     MWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELFIPGDKEGMNVELDKAIRLYDFITMGE
                     LVAYDALNRNESCGGHFREEYQTEEGEAKRDDENYFYVACWEYQGSDEKEPVLLKEPLV
                     YEAIKVQTRNYKS"
     CDS             complement(3982..4680)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_4"
                     /sec_met_domain="SucD_FumR (E-value: 3.3e-129, bitscore:
                     419.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMV
                     CEFLGANWYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQN
                     MLVLGIIVIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPV
                     FVVLYLVWLGALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLCFALVVVV
                     FFAKSLCGAC"
     CDS             complement(4843..5745)
                     /locus_tag="ctg12_5"
                     /transl_table=11
                     /translation="MRLETCCNRQIDCMVCPQKSEGVLVYRHYPKGQHFSAEKCTQNCM
                     IFMLKGELLVNSDEYPGTTLQSRQLILQAIGSKVELLALTEVEYIVYWFTELPLICEER
                     YKEILKRSEAPLTYTPLTAISMLEGLLKSLACYLNEQPYACSKYIEMKCQELVYILTCY
                     YPLHQISTFFYPISTYTESFQYFVMQNYDKVKNVEEFAHLGGYTTTTFRRLFKNMYGVP
                     VYEWILDKKREGILNDLQYTKQRISVISARYGFDSLSHFAHFCKDSFGDTPRALRKRSA
                     NGEKISIICKEQGKDQEDE"
     CDS             5851..6453
                     /locus_tag="ctg12_6"
                     /transl_table=11
                     /translation="MKKAIFFVYFICLVVSGLSAQNWDINTLHRVNSWDGKFVRNYNKI
                     ISRSEPYVAVGVPVAMAVAAWIKHDKGLLKDAVYVGTSVAGAFVVTYGMKYLVDRERPY
                     DKYPDRVHAYSHEGSPSFPSGHTATAFALATSLSVKYPKWYVIAPSALWACSVGVSRMN
                     EGVHYPSDVLAGAAIGAGCAVVNIYVNKWLNKWLFGE"
     CDS             6450..6557
                     /locus_tag="ctg12_7"
                     /transl_table=11
                     /translation="MILGANYAEYAELDKLNPHNPRLSLFQVGYWIIVL"
     CDS             complement(6536..8158)
                     /locus_tag="ctg12_8"
                     /transl_table=11
                     /translation="MEMMKKLFTIIICICAVTAQAQKPNNEALRKLQMAEFAITNLYVD
                     KVDEDKLVEEAIIKMLAQLDPHSTYNNAEEVKKMNEPLQGNFEGIGVQFQMIEDTLLVI
                     QPVSNGPSEKVGILAGDRIVAVNDSAIAGVKMSTEDIMSRLRGPKDSEVKLTIVRRGVD
                     DQLYFTVKRDKIPILSLDASYMIQPKTGYIRINRFGATTAEEFAEALKSLQKKGMKDLI
                     LDLQGNGGGYLNAAIDLANEFLKQKELIVYTEGRAARRSDFFAKGTGNFKNGRLIILVD
                     EYSASASEIVTGAIQDWDRGVVVGRRTFGKGLVQRPIDLPDGSMIRLTIARYYTPSGRC
                     IQKPYDSTANLDGRLTGENSQDKYNQELIDRFNHGEMIHADSIHFADSLKAQTKRMGRT
                     VYGGGGIMPDFFVPIDTTQYTDYHRNLVAKGVVIKATTGYIEKHRKELQNKYKKFEAFN
                     EKFEIDDNFLAEIRTLADKEKIKFDEKQYNQSLPLIKTQLKALIARDLWDMNEYFQVMN
                     STNQSVQQALKVLNEGIYSTIIQ"
     CDS             complement(8181..8639)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_9"
                     /sec_met_domain="CTP_transf_like (E-value: 2.1e-18,
                     bitscore: 58.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRAIFPGTFDPFTIGHSSVVSRALTFIDEIVIGIGINENKNTYF
                     PLEKREQMIRDYYRNEPRIIVQSYDCLTIDFARQVDASLIIRGIRTVKDFEYEETIADI
                     NRKLTGIETILLFTEPELTCVSSTTVRELLQYGKDISMFIPEGMEIRD"
     CDS             complement(8636..10570)
                     /locus_tag="ctg12_10"
                     /transl_table=11
                     /translation="MEDNNNMTLPLEEADNNITESPVSSVEYTDDNIRHLDDMEHIRVR
                     SGMYIGRLGDGSQNDDGIYVLLKEVMDNSIDEFKMGAGKRIEVTIEDSLRVSVRDYGRG
                     IPQGKLVEAVSKLNTGGKYDSKAFKKSVGLNGVGIKAVNALSSRFEVRSYRDGKVRIAI
                     FEKGTLLSDVTEDSTEESGTYIFFEPDATLFLNYSFQNQFVETLLRNYTYLNTGLTFIY
                     NGQRIVSRHGLEDLLKDNMTSEGLYDIIHLKGEDIEIAFTHTNQYGEEYYSFVNGQHTT
                     QGGTHQTALKEHIARTIKEFYNKNQEYADIRNGLVAAIAIDVEEPMFESQTKTKLGSNN
                     MWPAAPQEHKPAGPTVNKYVGDFIKTEVDNYLHKNPLVAEVMLQKIQDSEKERKAIAGV
                     TKLARERAKKANLHNRKLRDCRYHLSDGKGKDQETESCIFITEGDSASGSITKSRDVNT
                     QAVFSLRGKPLNSYGLTKKVVYENEEFNLLQAALNIEDGIETLRYNKVIVATDADVDGM
                     HIRLLIITFFLQFFPDLIKKGHVYILQTPLFRVRNKKKTSYCYTEEERVKAIEELGPNP
                     EITRFKGLGEISPDEFKHFIGKDMRLEQVSLRKTDLVKELLEFYMGKNTMERQNFIINN
                     LVIEEDLAS"
     CDS             complement(10688..11824)
                     /locus_tag="ctg12_11"
                     /transl_table=11
                     /translation="MAITIKKVTTRRELERFIRFNYLLYKNNPYSVPDLFDDMLNTFNK
                     KKNAAFEFCEADYFLAYREGKIVGRVAAIINHKANQTWNKKEVRFGWIDFIDDAEVSDA
                     LIRTVEEWGKERGMTHIQGPLGFTDFDAEGMLIEGFDQLSTMATIYNYPYYPQHLERMG
                     FEKDADWVEYKIYIPDAIPDKHKRISDLIQRKYNLKVKKYTSAKKIAQDYGQAIFELMN
                     EAYQPLYGYSALSQRQIDQYVKMYLPILDLRMVTLITDADDQLLAVGISMPSLAEALQK
                     AHGRLLPMGWYHLAKTIFLKKYPKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQQLGF
                     EYAESNPELELNGKVQAQWEYFKTEQHKRRRCFVKGIK"
     CDS             complement(11975..13009)
                     /locus_tag="ctg12_12"
                     /transl_table=11
                     /translation="MKVLYPVCIIFVLKIDIPMDILFLVGGLLLILLGANGLTDGAASV
                     AKRFHIPSIVIGLTIVAFGTSAPELTVSISSALKGSADIAIGNVVGSNTFNTLMIVGCT
                     ALFAPIAITRNTLKREIPLCILSSFALLICANDVLLDSSGENILSITDGLLLLCFFTIF
                     LSYTFAIAKRDGSMKEPEKEHLQEEDEIRLLPAWKSALYILGGLAGLIIGGNFFVDGAS
                     GIARGLGVSESIIGLTLVAGGTSLPELATSIVAALKKNPEIAIGNVIGSNLFNIFFVLG
                     CSASITPLRLTGITNFDLWVLVGSSILLWLFGIFFGKRIITRVEGSILILCYIAYTAVL
                     IYNL"
ORIGIN
        1 ttgaaaacag aatccagata taagagaact tataactgaa tcccgtttct atttacacaa
       61 aattatggat actgcctaaa aaactgaatt acttctattt tattcattcc ccgaaacttc
      121 tttatgaaag ttttcgggga atgtttcttt tatgagtatt atttatctat ttttgtcact
      181 gcaacaaaca aacaaatcta cttgccgatg cccaactctt ctgcttgcag aggtaaaaaa
      241 caatgcgctc aatgtcccaa ggctgtggac aatgcaataa tatatgcttc ccacctcaga
      301 ggattccatc tgccggcgcg aaagtgtgag gaaaatatta taattttcct gctgaaagga
      361 gaagtgcttg tcaacagtaa ggagtatgcg ggaactgtgt tgcatgcagg tgagttcatc
      421 cttcaagcta ttggttccaa gtacgaaata cttgccatga cggatgtgga atgcgtttgt
      481 taccggttca gtaagcctga attcttctgt gaggaccggt ataaccatat tatgaaagag
      541 gttacccctc cattgatatt ctatcctttg accattactc ccgagttgca gctctttctg
      601 gaaagttcca aggcctattt gtccgaggag aagatttgcc gggaaatgct ttgtttcaaa
      661 cggaaagaac ttgctttcat tcttggaaat tactactccg actatgagct ttccatgctg
      721 atacatcctc ttgcccagta tactaattcc ttccactact ttgtcttgca gaatcatgcc
      781 aaagtcaaga cggtagagga acttgcccag ttgggaggat atacagtagc tactttccgg
      841 cgtatattca attctgtttt tcatcaaccg gtgtacgagt ggatgatgga acggaggaag
      901 gaaagcgtgg tttatgaact tcgttatacg gatgcttcta tatcagagat ttgctataaa
      961 tatggctttg aatcgctgcc tcatttttcc aatttctgca aaaagaattt cggggcttct
     1021 ccccgtagct tgcgtgccgg caatttatct gaagtaaacg gcatgtcata aaaaaactcc
     1081 tccggcggtt tcccggcaga ggagtctctt gtgatattaa tcaaatatag tgaaagctga
     1141 gtgataaatc tgagcttgct caaaaggttt atccgaagcg catcctatat tatttgcaga
     1201 aagaccggat tagtctttca gtttcgcaat gataaagtcg cggttcaggc gagcaatgtt
     1261 gctgatggaa acattcttcg ggcattcagc ttcgcacgca cgagtgtttg tacagttacc
     1321 gaaaccgagt tcgtccatct tgctcaacat agccttggca cggcgcaatg cttccggttt
     1381 gccttggggc aacaggttca gctggctcac cttggcagaa acgaacagca tagcagaacc
     1441 gttcttacaa gcagccacac aagcaccaca accgatacag ctggcagcat ccatagcctc
     1501 gtcagcgatg ggcttcggaa tcaggatagc gttggcatcc tggggagcac cggtacgtac
     1561 gctgacgtag ccgcctgcct gcataatctt gtcgtaggcc gtacggtcga ccatcaagtc
     1621 cttgataacc gggaaaccgg cagagcgcca cggttcaaca gtgatggtat cgccgtcgtt
     1681 gaaacgacgc atataaatct ggcaagtcgt agcgccggtt gcaggaccgt ggggatgtcc
     1741 gttgatgtag agcgaacaca taccgcagat accttcgcgg cagtcgtggt cgaatacaac
     1801 cggttcttta ccttcagaaa tcagctgttc gttcaggata tccagcattt cgaggaatga
     1861 agtatcgccc gggatatctt tcatttggta tgtttcaaaa gcgccttttg ctttcggacc
     1921 cttctggcgc cataccttga gcgtaaatga tatattttta tccattttct ttaattcttt
     1981 aaatgttcaa cttcccgatt agctcttgta gttacgagtc tgtaccttga ttgcttcgta
     2041 aaccagcggc tctttcagca ataccggttc cttttcgtca gaaccctgat attcccagca
     2101 agccacgtag aagtagtttt catcgtcacg cttggcttcg ccttcttcag tctgatattc
     2161 ttcacggaag tgaccaccgc agctttcgtt acggttcagt gcatcgtaag caaccagctc
     2221 gcccatagtg atgaagtcgt acagacggat agccttgtcg agttctacat tcataccttc
     2281 cttgtcgccc gggatgaaca gttctttctc gaactccttg cggacttctt tcagcttctt
     2341 cagaccttcc ttcaagcctt cagccgtacg tcccatgcct acatattccc acatgatgtg
     2401 gcccagttcc ttgtggatag agtctacaga cttcttaccc ttaatattca tcatccagtc
     2461 aatcttgtcc tgaacagcct tttctgcagc tgcaaattcg ggcaggtcgg tagagaaacg
     2521 gggaactgta atctggtcgg ccaggtaatt ctggatagtg taaggcaata cgaagtaacc
     2581 gtcggccaga ccttgcatca gcgcagaagc accgaggcgg tttgcaccgt ggtcggagaa
     2641 gttacattca ccaatagcga acagaccctt gatggaggtc atcagttcat agtcaaccca
     2701 gataccgccc atggtatagt ggatagccgg ataaatcatc atcgggtttt cgtatgggct
     2761 gacatcagtg atttcttcat acatatcgaa gaggttgccg taacgttgtg caacgacatc
     2821 tttacccaga cggttgatag cttcggagaa gtcaaggaat acggcaaggc cggtgttgtt
     2881 cacgccataa cccttgtcgc agcgttcttt ggctgcgcgg ctggcaacgt cacgcggaac
     2941 gaggttaccg aatgctggat aacggcgttc caggtagtag tcgcggtctt cctcgggaat
     3001 atcttttcct tgcagtgtac cttcctgcag tttcttggca tcttccagct tcttcggaac
     3061 ccagatacga ccatcgttac gcagagattc ggacatcaaa gtcagcttag actgcttgtc
     3121 accgtgaacc gggatacaag tggggtgaat ctgtacgtaa gcagggttgg caaaccaggc
     3181 acctttacgg tagcaagcca ttgctgcaga gcagttacat gccattgcat tggtagaaag
     3241 gaagtaggca ttgccgtaac caccggtagc gattaccaca gcgtgggcgg caaaacgttc
     3301 caatttaccg gtaacgaggt tctttgcaat gataccgcgg gcacgtccgt caatgaggac
     3361 aacgtcttcc atttcgtagc gggtatacag tttcacagtg cctacgttca cctggcggct
     3421 caatgcagag tatgcaccca gcaacagctg ttgtccggtc tgacccttgg catagaaagt
     3481 acgggatacc tgagcaccac cgaaagaacg gttgtccagt gtaccgccgt attcgcgggc
     3541 gaaaggaaca ccttgtgcaa cgcattggtc gataatattg ttggatactt cagccagacg
     3601 gtaaacgtta gcttcgcggg cacggtagtc gccacccttt actgtatcgt agaacagacg
     3661 gtatacagag tcaccgtcgt tttggtaatt cttagcagca ttgataccac cttgtgcagc
     3721 gatggagtgt gcacggcgcg gagagtcctg gatgcagaag ttgaatactc tgaaacccat
     3781 ttcgcccaga gaggcggcag cactggcacc ggcaagtccg gttcctacta cgatgatgtc
     3841 cagacgacgt ttgttggcag ggtttactaa tttttggtga gccttataat tggtccattt
     3901 ctcagccacc ggtccttccg gtattttaga atctatctta gtcataatgc aatttacaat
     3961 ttagtcattt acaatttgaa tttagcaagc gccgcacaat gattttgcaa agaatacgac
     4021 aactaccaga gcgaagcaga ggacaacgat agtagaatag atgttggaga tacatttcca
     4081 acggttaatc catactttgt tgttccagcc caaagactgc atggagctcc agaaaccgtg
     4141 agtgaggtgg aaccacaatg cgcccagcca aacgaggtaa agcactacga ataccggatt
     4201 gctgaaggtg ttttgaatgt gatagacacc gttggctgca tatgccagcg tgagggtgtc
     4261 ggcatgcatg cccatgttgt gcatcaactc gggaagctgc attttagccc agaagtttac
     4321 caggtgcagg cccaaaccca cgattacgat gatacccagt acgagcatgt tctgagaagc
     4381 ccattccaca gtcttgggct tttccgtaac ggcatagcgt tcgctaccac gtgccttacg
     4441 gttctgcata gtcagccaga aagcgtagat gatgtggatg atgaataagg cagccagacc
     4501 taccgtagcc accaatgcgt accagtttgc tcccaggaac tcacaaacca tgttgtagcc
     4561 attagccgag actaatgcaa ccaggttcat cgccatgtga aatgtcagaa acaggacaag
     4621 ggcgataccg gtaacgctca tcaccacttt ccttcctaca gatgaattac ttaaccacat
     4681 aaatgattga atttaagtta tttaatagtt tgaaaatttg ttctatcagg atacttctgt
     4741 aaatgtttcg caaaaatagg agaaatccag cgataaagca agcgattaaa gaaataattc
     4801 cgtaatccgg cagaatgcga agtttacgga caagtaaaag gtttactcgt cctcctggtc
     4861 tttgccttgc tctttgcaga taatggaaat cttttctccg tttgccgaac gttttctcag
     4921 ggcgcggggc gtgtctccga aagagtcttt gcagaagtgg gcaaagtggg atagggaatc
     4981 aaagccatag cgggcgctga tgactgaaat gcgttgtttg gtgtattgca ggtcgttcag
     5041 aattccttca cgtttcttgt ccagaatcca ttcatagacc gggaccccat acatattttt
     5101 aaacagacgg cggaatgtgg tggtggtata tccaccgagg tgggcaaact cttccacatt
     5161 cttcaccttg tcgtagttct gcatgacgaa atattggaag ctttccgtat aagtgctgat
     5221 ggggtagaag aatgtactga tttggtgtag cggatagtag catgtcaata tgtataccaa
     5281 ttcctggcat ttcatttcaa tgtatttgct gcacgcatag ggttgctcgt tgaggtagca
     5341 ggcaaggctt ttcaggagcc cttcgagcat ggaaatcgcg gtaagcgggg tataagtcaa
     5401 gggggcttcc gagcgtttca gtatctcctt gtagcgctct tcgcaaatca gaggaagctc
     5461 ggtgaaccaa tagacaatat attccacttc ggtcaaagcc aggagttcta ctttggagcc
     5521 gatggcttgc aagatgagct ggcggctttg gagagtggtg cccggatatt cgtcactgtt
     5581 tacaagtaat tcacctttca gcataaatat catgcagttc tgtgtgcact tttcagcaga
     5641 gaaatgttgt cccttggggt agtggcggta aaccaatact ccttctgatt tttggggaca
     5701 taccatacaa tcaatctgtc ggttgcagca agtttccagt ctcatgaaat gattagcgaa
     5761 ttattataaa tgtggcaaca aagatagaat ttttttgtga aaactctatc tatttgtcct
     5821 atctttgcgt caaactaata taaaggactt atgaaaaagg ctattttttt tgtatatttt
     5881 atctgccttg ttgtatccgg tctttcggca cagaattggg atattaacac tttgcatcgg
     5941 gttaacagtt gggatggcaa gtttgtccgt aactataata agataatttc acgttcggag
     6001 ccctatgttg ctgtcggtgt tccggtggcg atggcggttg ccgcttggat aaaacatgat
     6061 aagggtttgc tgaaagatgc ggtctacgta ggtacaagtg tagcgggggc ttttgttgtg
     6121 acttatggaa tgaaatatct ggtggaccgt gagcgtcctt atgataaata tcccgacaga
     6181 gtgcatgcat atagccatga aggcagcccg tcttttcctt ccggacatac ggcgacggct
     6241 tttgcccttg ccacctcgct cagtgtaaag tatcctaaat ggtatgtgat agctccgtct
     6301 gccctgtggg cttgttccgt gggagtttcc cgtatgaacg agggagtgca ttatccgtca
     6361 gatgtgttgg cgggggctgc aatcggtgct ggatgtgctg tggtcaacat ctacgtcaac
     6421 aagtggctga ataagtggct gttcggagaa tgattttagg cgcgaattac gcggaatacg
     6481 cggagttaga taaactaaat ccgcataatc cgcgcctaag tttgtttcaa gtcggctatt
     6541 ggataatagt gctgtagatg ccttcgttca gcacttttag agcttgctgc acgctctggt
     6601 tcgtgctgtt catcacctgg aagtattcgt tcatgtccca taggtcacgg gctatcaagg
     6661 ctttaagttg tgtcttgatg agcggtaggg attggttgta ctgtttctcg tcaaacttga
     6721 ttttctcttt gtcggcaagc gtacgtattt cggcaaggaa gttatcgtct atctcgaact
     6781 tctcgttgaa ggcttcgaat ttcttgtatt tgttctgcaa ctccttccgg tgcttctcga
     6841 tgtagccggt agtggctttg ataaccacgc ctttggctac gaggttgcgg tgatagtctg
     6901 tgtactgggt agtgtcgatg gggacgaaga agtcgggcat gatacctcca cctccgtaaa
     6961 cggtacgtcc catacgcttg gtctgtgctt tcagggagtc ggcaaaatgg atactgtccg
     7021 catgaatcat ttctccatga ttgaagcggt ctatcagttc ctggttatac ttatcctgac
     7081 tgttctcgcc ggttaggcgg ccgtcgaggt tggcggtgct gtcgtaaggc ttctggatac
     7141 aacggcccga aggagtatag tagcgggcga tagtgaggcg aatcatggaa ccgtccggca
     7201 ggtcgatagg acgctgtact aatcccttgc cgaaggtgcg gcgtcctact accacgcctc
     7261 tgtcccagtc ctggatggct ccggtcacga tttcactggc agaagcggag tactcgtcca
     7321 ccaatatgat gagacggccg ttcttgaagt tgcccgtacc tttggcaaag aaatcactgc
     7381 ggcgtgcggc ccttccttcg gtgtagacga tgagttcttt ttgcttcaga aattcgttgg
     7441 caaggtcgat ggcggcattc agataccctc ctccatttcc ttgcaggtcg aggatgaggt
     7501 ctttcattcc tttcttttgc aggcttttca gggcttctgc aaactcttcg gcggtggttg
     7561 ccccgaagcg gttgatacgg atatagccgg ttttgggttg tatcatgtaa gatgcgtcca
     7621 ggctgaggat gggaattttg tcacgcttca cggtgaagta cagctggtcg tccacgccac
     7681 ggcgcacgat ggtgagtttc acttccgagt ctttcggtcc gcgcaggcgg ctcataatat
     7741 cttccgtgct catttttact ccggcaatgg cgctgtcatt gacggctacg atacggtcgc
     7801 cggcaaggat gcccaccttc tcggaaggtc cgttgctcac gggttgtatc acaagcaggg
     7861 tatcttctat catctgaaac tgtacgccga tgccctcgaa attgccttgc aacggctcgt
     7921 tcatcttctt cacttcttcg gcgttgttgt aggtggagtg cgggtcgagt tgtgccagca
     7981 tcttgatgat ggcttcttcc accagcttgt cttcatccac cttgtccaca taaaggttgg
     8041 tgatggcaaa ctctgccatt tgcagtttgc gcagggcttc attgttcggc ttttgcgctt
     8101 gtgccgtcac cgcgcatata catattataa tagtaaatag ttttttcatc atttccattt
     8161 taatccctaa tcctttatcc ttaatcccta atctccattc cctccggtat gaacatgctt
     8221 atgtccttgc cgtattgcag cagttcgcgc acggtggtgg aactgacgca ggtaagttcc
     8281 ggctcggtga agagcaggat ggtttctatg ccggtcagtt tgcggttgat gtcggcaatg
     8341 gtttcctcgt attcgaaatc cttcacggtg cgtatgccgc gtattatcag actggcatct
     8401 acctgccggg caaagtcgat agtcaggcag tcataggact gcacaatgat gcgcggctcg
     8461 ttccggtagt agtctcgtat catttgttcg cgcttttcca aggggaaata cgtattctta
     8521 ttttcattga tgccgatgcc tatgacgatt tcgtctataa aagtcagtgc acggctcact
     8581 accgaagagt gtccgatagt aaacgggtcg aatgttcccg gaaagatagc tcttctcatg
     8641 atgccaaatc ttcttctata accaagttgt tgataataaa gttttgtcgt tccatggtat
     8701 tcttacccat gtagaattcc agcagctctt ttacgaggtc tgtcttgcgc agggacactt
     8761 gttccagacg catatccttg ccgataaaat gcttgaactc gtcgggcgag atttctccca
     8821 gacctttgaa tcgggtgatt tcggggttgg gacccagttc ttcaatggct ttcacacgtt
     8881 cctcctctgt atagcaataa cttgtcttct ttttgttgcg cacgcggaag agaggggttt
     8941 gcaggatata tacatgccct ttctttatca ggtcggggaa gaactgcagg aagaaggtga
     9001 tgatgagcag gcggatgtgc atgccgtcca catcggcatc ggtagctacg atgactttgt
     9061 tgtagcgcag tgtctctatg ccgtcttcta tattcaaggc tgcttgaagc aagttgaatt
     9121 cttcgttttc ataaactact ttcttggtga gtccgtagga atttagcggt ttaccacgca
     9181 ggctgaatac tgcttgggta ttcacgtcgc ggctcttggt gatggaaccg ctggcggagt
     9241 ctccctcggt aatgaagatg caggattcgg tttcctggtc tttgccttta ccgtcactca
     9301 agtggtagcg gcagtcgcgc agcttgcggt tgtgcaggtt ggctttcttg gcgcgttcgc
     9361 gtgccagctt ggtgacgccg gcaatggctt tgcgctcttt ctcggagtct tgtatctttt
     9421 gcagcatcac ttcggccaca agcgggttct tgtggaggta gttgtccact tccgtcttga
     9481 tgaagtctcc tacgtatttg ttcaccgtgg ggccggcggg cttgtgttcc tgcggcgcgg
     9541 caggccacat gttgttgctg cccagtttcg ttttggtctg gctctcgaac atgggttcct
     9601 ccacgtcgat ggcaatggcg gctaccagtc cgttgcggat gtcggcatat tcctggttct
     9661 tgttgtagaa ctccttgatg gtacgggcaa tgtgttcctt caaggcagtc tggtgtgtgc
     9721 cgccttgggt ggtgtgttgc ccgttgacaa aggagtagta ctcttcgccg tattggttgg
     9781 tgtgtgtgaa ggcaatctcg atgtcctctc ctttcaggtg gatgatgtcg taaaggcctt
     9841 cgctggtcat gttgtctttc agcaagtcct ccagcccgtg gcgggaaacg atgcgctggc
     9901 cgttgtaaat gaaggtgagg cccgtattca ggtaggtgta gttgcgcagc agggtttcta
     9961 cgaactggtt ctggaaggaa tagttcaaga agagtgtggc gtccggttcg aagaagatat
    10021 aggttccgct ttcttctgtc gagtcttcgg tcacatcact caacagcgtt cctttttcaa
    10081 agatggcgat acgtaccttg ccgtcgcggt agctgcgtac ttcgaagcgg ctgctcagcg
    10141 cattgactgc cttgatacct acgccgttca gtccgacact tttcttgaaa gccttcgagt
    10201 catatttacc cccggtattc agtttgctga ccgcctctac cagtttgcct tgcggaatgc
    10261 ctcgtccata gtcgcgtacg ctgacacgca gactgtcttc tatagtcact tctatacgct
    10321 ttccggcacc catcttgaac tcgtcgatgc tgttgtccat cacttctttc agcaacacat
    10381 agatgccgtc atcgttctgt gagccgtcgc ccagacggcc tatgtacata ccggaacgga
    10441 cacggatatg ctccatgtcg tccaggtggc ggatgttgtc gtcggtatat tccacgctgg
    10501 aaacggggct ctctgtgata ttgttgtctg cttcttccag cggcagggtc atattgttgt
    10561 tatcttccat aagtacgtta ttccttcata ttgcgcattg cgacaaaggt aatgagaaat
    10621 tcgggggttc gcaaaaaaat aatgtctttt atggacttct gacaagctta tattctggat
    10681 ttagaactta ttttattcct ttcacaaagc atcttctccg tttatgctgt tccgtcttga
    10741 agtactccca ctgcgcttgc accttgccgt tcagctccag ctccggatta ctctcggcat
    10801 actcgaaacc aagttgctga tagacgggga taaggtcgga gaacaacaat gcatttaccc
    10861 ccttgttctg atactccggt ttcacggcaa ccagcagcaa atcgagcatc ttgggatatt
    10921 tcttcaagaa gatggtcttg gccaggtgat accaacccat aggaagcagg cgcccgtggg
    10981 ctttttgcaa cgcttcggcg agtgacggca tggaaatgcc tacggcaagc agctggtcat
    11041 cggcatcggt aatcaatgtc accatgcgta ggtcgaggat gggcaggtac atcttgacgt
    11101 attggtcaat ctgccgttgg ctcagtgcag aatagccata gagtggctga taggcttcgt
    11161 tcatcagttc gaagatggcc tgaccgtagt cttgggcaat cttcttggca gatgtgtatt
    11221 tctttacctt gaggttatac ttgcgctgga tgaggtcgga gatgcgcttg tgcttgtcgg
    11281 gtatggcgtc gggaatgtag attttgtact ccacccaatc ggcatccttc tcaaagccca
    11341 tgcgttccag atgttgcgga tagtagggat agttataaat ggtggccatg gtgctgagct
    11401 ggtcgaatcc ttcgatgagc ataccttcgg catcgaaatc tgtgaatccc agcgggcctt
    11461 gtatatgtgt cattccccgt tcttttcccc attcttccac ggtgcgaatc agggcatcgg
    11521 agacttccgc atcatcgatg aagtctatcc agccgaagcg gacttccttt ttgttccagg
    11581 tttggtttgc cttgtggttg atgatggcag ctacacgtcc tacgatttta ccttcccgat
    11641 aagccaggaa atagtcggct tcacaaaatt cgaatgcagc gtttttcttc ttgttgaagg
    11701 tgttgagcat gtcatcgaaa aggtcgggga cggaataagg gttgtttttg tatagcaggt
    11761 agttgaaacg gataaagcgc tccagttccc gtcttgtggt tactttcttg attgtaattg
    11821 ccatagttgt tcaatattga gaccacaaag gtaatgcaaa ctgagagcag aacaaaataa
    11881 gcttgcttat tttttatgcc gaggtacagc ttgccttatt taaaaatacg tgataatctt
    11941 taaaataccg cgtagggtgt ttgtaaattt gctgttagag gttgtatatc agtaccgctg
    12001 tgtaggcaat gtagcagaga atcagaatgc ttccttccac ccgggtgatg atgcgtttcc
    12061 cgaaaaagat accgaacagc caaagcagga tgctggaccc tacgagtacc cacaaatcga
    12121 aattggtgat gcccgtcaga cgcagtggag tgatggaggc cgaacaaccc agtacgaaga
    12181 atatattgaa gagattactt ccgatgacgt ttccgatggc tatttcgggg tttttcttca
    12241 aggcggctac gatggaggtg gcgagttcgg gtaatgaagt gccgcctgct acgagcgtga
    12301 gaccgatgat ggattcgctg acacccaatc cgcgggctat gccgctggca ccgtctacaa
    12361 agaaattacc tccgatgatg aggccggcaa gtccgccgag aatgtatagg gcggatttcc
    12421 acgcgggtaa cagcctgatt tcgtcttctt cctgtaagtg ctccttttcc ggttccttca
    12481 tacttccatc cctttttgca atggcaaaag tataactcag aaaaatggta aagaagcata
    12541 gcagcaatag gccgtcggtg atgctgagta tgttctcccc actgctgtcc agtaagacgt
    12601 cgttggcaca aatcagcagg gcgaaggatg aaaggatgca aaggggtatt tcgcgtttca
    12661 gtgtgttacg ggtaatggct atcggggcaa aaagggccgt acaacccaca atcatcaggg
    12721 tattgaacgt attgcttccc accacattgc cgatggcaat gtctgcactg ccttttaggg
    12781 cagaggatat gctgacggtg agttccggtg cggaagtacc gaaggcgaca atggtaagcc
    12841 cgatgacgat ggacggtata tggaaacgtt tggcaacgga tgcggcaccg tctgtcaagc
    12901 cattggcacc cagaagaatg aggagcagtc ctccgacaag aaacaatata tccataggta
    12961 tgtcaatttt gagtacaaag ataatgcaaa ccggatacag aactttcatg tttgcatgaa
    13021 aaagttatgt tgattaggat aggaagttaa aaacattccg tatgtttgaa gcatttattg
    13081 ggtatatttg cataattaaa gaatcaaatc aagaagttta tatatgaagg ttatccgtgc
    13141 tttctgtctt tgttggctgt tgatgctggc agacggagtg tcagctcagt tggtagataa
    13201 agtgctcagt gttttaggtg aggatagtgt ggggagtgtc acagtggcaa ggactgactc
    13261 cgattcgatt cagttgtcgc ttgtccggca ggagttggaa acagcccggc tgaatgaggc
    13321 gaacctgcgg atggaaatgg agcagatgaa gttggcgggc tatgcggccg attcggtgaa
    13381 gctggcattg cagaaacaac gcattgattc gttgcggacg gtgacaccgg gtattccggt
    13441 ggtggtggag aaggacactt tgttctatct gtatgccaag cgtggagggc atacgcccca
    13501 acagcgagcc aaagatgtaa gcaacgtcat cgaagcattg ggcacgcgtt tcaatctgcg
    13561 tccggactct gtttatttag agagtacgga tattgttaca gacttgatgt atggcgaaaa
    13621 ggtcatcatt tcctttaccg atcaggatgc tttgtgggaa aactgtaccc gcgaccagct
    13681 ggccgccagc aagaggcatg tcgtggtgga caaactgaaa gccatgcaga aggagcatag
    13741 cttgtggcag ttgggtaagc gtatcttgta ctttatcctg gtgcttgtgg gacagttctt
    13801 cttgttcaag tttaccaact ggctgttcag aaaactcaaa ctacgcattc agaagctgaa
    13861 ggataccaag ctgaaaccga tctctattca ggattatgaa ttgctggata cgcagaagca
    13921 ggtcaacctg ctggtgtttg ttgccaacct ggtgcgttat gtagtcatgc tgttgcagtt
    13981 gctgctgacg gttccgttat tattctccat tttccctcag accaagagct tggcttatac
    14041 attattctcc tacatctgga atcctataaa ggtcatcttg aatggaatag ccgactatat
    14101 acccaatctg ttcactatct ttgtgatatg ctatgcggtg aagtatctgg tcagactggt
    14161 gcgttatctt gccaatgagg tgcaggctga acggctgaag ataaacggct tctatccgga
    14221 ttgggccatt cctacctatc atattgtgcg cttcttgctt tatgcgttta tgattgccat
    14281 gatttaccct tatctgccgg gttccaagtc gggagtcttc cagggaatct ccgtgtttgt
    14341 cggcttgatt gtttcgctcg gttccagtac ggttatcggc aatatcattg caggactggt
    14401 cataacctac atgcggcctt tcaagctggg tgaccgcatc aagctgaacg atactacggg
    14461 caacatcatt gagaaaacac cgctcgtcac ccgcatccgt actccgaaga atgaggtggt
    14521 gaccattccg aactctttca tcatgtcttc ccatacggtc aattacagcc agtctgcccg
    14581 tgagtatgga ttgattatcc attcggaggt cagtattggc tacgatgttc cgtggcggaa
    14641 gacacatcag ctgttgatag aggctgcatt gaatactcct
//
