Select genomic region:
Overview
6.1
7.1
9.1
11.1
12.1
17.1
33.1
55.1

### Identified primary metabolite regions

c00006_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_6)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 6.1 | Fumarate2succinate | SCFA | 27,848 | 51,318 | Fumarate to succinate B. thetaiotaomicron | SUC | 100%

c00007_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_7)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 7.1 | Pyruvate2acetate-formate,GR_fatty_acids | Putative | 10,305 | 38,930 | Pyruvate to acetate-formate B. thetaiotaomicron | PFL_acetate | 100%

c00009_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_9)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 9.1 | succinate2propionate | SCFA | 25,409 | 50,117 | Succinate to propionate B. theta | PRO | 75%

c00011_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_11)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 11.1 | TPP_AA_metabolism | Putative | 326,240 | 352,321 |

c00012_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_12)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 12.1 | porA | SCFA | 36,313 | 59,156 | porA C. sporogenes | POR | 80%

c00017_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_17)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 17.1 | Rnf_complex | E-MGC | 30,510 | 55,744 | Rnf complex C. sporogenes | RNF | 83%

c00033_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_33)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 33.1 | NADH_dehydrogenase_I | E-MGC | 49,105 | 79,336 | NADH dehydrogenase I Bacteroides sp. | NADHD | 80%

c00055_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_55)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 55.1 | PFOR_II_pathway | SCFA | 55,442 | 78,999 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 6.1 | Fumarate2succinate | SCFA | 27,848 | 51,318 | Fumarate to succinate B. thetaiotaomicron | SUC | 100%
Region 7.1 | Pyruvate2acetate-formate,GR_fatty_acids | Putative | 10,305 | 38,930 | Pyruvate to acetate-formate B. thetaiotaomicron | PFL_acetate | 100%
Region 9.1 | succinate2propionate | SCFA | 25,409 | 50,117 | Succinate to propionate B. theta | PRO | 75%
Region 11.1 | TPP_AA_metabolism | Putative | 326,240 | 352,321 |
Region 12.1 | porA | SCFA | 36,313 | 59,156 | porA C. sporogenes | POR | 80%
Region 17.1 | Rnf_complex | E-MGC | 30,510 | 55,744 | Rnf complex C. sporogenes | RNF | 83%
Region 33.1 | NADH_dehydrogenase_I | E-MGC | 49,105 | 79,336 | NADH dehydrogenase I Bacteroides sp. | NADHD | 80%
Region 55.1 | PFOR_II_pathway | SCFA | 55,442 | 78,999 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%

No primary metabolite regions were found in these records:
  c00001_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_1)
  c00002_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_2)
  c00003_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_3)
  c00004_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_4)
  c00005_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_5)
  c00008_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_8)
  c00010_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_10)
  c00013_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_13)
  c00014_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_14)
  c00015_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_15)
  c00016_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_16)
  c00018_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_18)
  c00019_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_19)
  c00020_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_20)
  c00021_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_21)
  c00022_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_22)
  c00023_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_23)
  c00024_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_25)
  c00026_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_30)
  c00031_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_31)
  c00032_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_32)
  c00034_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_34)
  c00035_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_38)
  c00039_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_39)
  c00040_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_40)
  c00041_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_41)
  c00042_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_43)
  c00044_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_44)
  c00045_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_45)
  c00046_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_46)
  c00047_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_47)
  c00048_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_48)
  c00049_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_49)
  c00050_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_50)
  c00051_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_51)
  c00052_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_52)
  c00053_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_53)
  c00054_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_54)
  c00056_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_56)
  c00057_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_57)
  c00058_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_58)
  c00059_gnlPro.. (original name was: gnl|Prokka|NCOHLEED_59)

Compact view
c00006_gnlPro.. - Region 1 - Fumarate2succinate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 27,848 - 51,318 nt. (total: 23,471 nt) Show pHMM detection rules used
Fumarate2succinate: (Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or Fer4_7 or SucD_FumR))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00007_gnlPro.. - Region 1 - GR_fatty_acids,Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 10,305 - 38,930 nt. (total: 28,626 nt) Show pHMM detection rules used
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)
GR_fatty_acids: (minimum(1, [Gly_430_pcre, Gly_8-9_TMA, Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline, PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1, ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C, Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00009_gnlPro.. - Region 1 - succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 25,409 - 50,117 nt. (total: 24,709 nt) Show pHMM detection rules used
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00011_gnlPro.. - Region 1 - TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 326,240 - 352,321 nt. (total: 26,082 nt) Show pHMM detection rules used
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00012_gnlPro.. - Region 1 - porA
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 36,313 - 59,156 nt. (total: 22,844 nt) Show pHMM detection rules used
porA: (Fer4_7 and TPP_enzyme_C and POR and POR_N and PFOR_II and not (EKR or Fer4_16))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00017_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 30,510 - 55,744 nt. (total: 25,235 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00033_gnlPro.. - Region 1 - NADH_dehydrogenase_I
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 49,105 - 79,336 nt. (total: 30,232 nt) Show pHMM detection rules used
NADH_dehydrogenase_I: (Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00055_gnlPro.. - Region 1 - PFOR_II_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 55,442 - 78,999 nt. (total: 23,558 nt) Show pHMM detection rules used
PFOR_II_pathway: cds(POR and POR_N and PFOR_II and EKR and Fer4_16 and TPP_enzyme_C)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.