LOCUS       c00022_gnlPro..        22843 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EKBBMOLL_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 13:25:13
            Original ID  :: gnl|Prokka|EKBBMOLL_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 353217
            Orig. end    :: 376060
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22843
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[363217:366173]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12956
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..22843
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /detection_rules="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /kind="chemical_hybrid"
                     /product="Pyruvate2acetate-formate"
                     /product="GR_fatty_acids"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..22843
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /product="GR_fatty_acids"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /rules="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /tool="gutsmash"
     protocluster    728..22843
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[363944:372020]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_fatty_acids"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      10728..18803
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_fatty_acids"
                     /protocluster_number="2"
     CDS             complement(2296..3000)
                     /locus_tag="ctg22_309"
                     /transl_table=11
                     /translation="MKKLRMTLAASMLLFLTAIVLQSCLDDWDDKYDTLFAVGTVKVIE
                     GKDYYFSLDEGSKLYPSDTTYVHDYAVIDGQRAFIYFRELEEKLPGYEYNAQIKHIENI
                     LTKDIYSMPAEKADSIGDDNINATDLWITGEYLNIKYQFYHSNNEDKKHMLNLVINEAS
                     TGENDKPDYVNLEFRHNAYNDSQLTLGTGLASFKLDNIAEQLKEKKGLNIRVKSLYDGE
                     RFMTIDIKKENN"
     CDS             3181..3729
                     /locus_tag="ctg22_310"
                     /transl_table=11
                     /translation="MEEQELAERCRQGDNLARKELYERYAGRMLSVCLRYAGDRETAQD
                     LMHDGFLKLFDSFDKFTWRGEGSLRAWMERVMVNTVLQYLRKNDVMNQSSALENAPEAY
                     EEPEGSSIDVIPQKVLMQFISELPAGYRTVFNLYIFEEKSHKEIARLLGINEKSSASQL
                     TRAKATLAAKVREWMKRND"
     CDS             3742..5058
                     /locus_tag="ctg22_311"
                     /transl_table=11
                     /translation="MEDELWLKKIKDKLEDYSEPLPVAGWERLEKELSVSGAPITGPHR
                     MIPFRRWAVAAAAVLLVAVSSVSLWLLQSPVGNEMRHTSVPALAVAPDVLPEQTVPAVR
                     TNPIEPAYRAHGNASAPNREASRPLVAQHIRISVDDERQEEMLPVETAGEAVGIGQQAE
                     EPVMEDTDHATAMQAEEPERTRKDRYRPSGRDKLHLPERNSSGRDTKGWAVGLSVGNTG
                     GFSLANEGEANVMSDYMPGSPIYGGNVDLSSTANGIVTIPDGQELVFKDGMPYLQRREK
                     KIADIDHKQPLSFGVSVRKNLAKGFSVESGLTYTYLASDVRYEGSSEKISQKLHYIGIP
                     VRANWNFVDAKNFTMYVSAGGAIEKCVYGKIGTESETVKPVQLSVMGAVGAQYNISNRV
                     GLYVEPGVSYFFDDGSSIQTIRKENPCNFTLQAGIRLTY"
     CDS             5235..7697
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 80.1; E-value: 3.4e-25)"
                     /gene_kind="other"
                     /locus_tag="ctg22_312"
                     /sec_met_domain="Fn3-like (E-value: 1.8e-24, bitscore:
                     80.1, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 1.8e-55, bitscore:
                     182.8, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 1.2e-49,
                     bitscore: 163.4, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKKKVALSGLLLCCAITAKAQVCITPQVEQRARELVSQMTLEE
                     KIDYISGPKSFYIRAVPRLGIPEIRMADGPQGIRNNTQSTLYPCGILSASTWNRKLARE
                     LGHGLARDAKARGVSILLGPGVNIYRSPLCGRNYEYFGEDPYLTGETAKEYILGVQEEG
                     VMATVKHFAANNQEWSRHHASSDVDERTLQEIYFPAFRKAVQEAGVGAVMDSYNPLNGV
                     HATENSWLNIDVLRKQWGFKGILMSDWTSVYSGVGAANGGLDLEMPVGKFMTREILIPA
                     IENGIVKEETIDAKVRHILQTLIAFGALDTPREDKSIDKDNAQSKEIALDLAREGVVLL
                     KNDNGTLPYRNGRTLVIGPNADIIPTGGGSGFVTPYSVVSLYDGMVQLKGGRQIELLSD
                     SILYKDMSQQIYTDGSFTQNGFKGEYYNTRNLTGELFQAAIEPAIDHAWKYGAPFDGMP
                     VDQFSARWTGVYKADKDGTVKFQLAGDDGYRLFVNDKLITGDWGNHSFSTRSAFMQVSA
                     GEIYRLRIEYFDNVGEATVSFQAGMMDEERLASSLKHARNVIVCAGFNSSTEGEGFDRP
                     FALSYGQEYLINKVASLHDNVAVVVNAGGGIDFRNWGQSVQAILMAWYPGQEGGKALAE
                     IITGKLSPSGKLPVSIEEKWEDNPVYGNYYDNRNVPHKRVQYAEGVFVGYRGYDRNGKQ
                     PLYPFGYGLSYSSFEYSNLSVEKTGGSRVTVSFDIKNTGKMDAAEAAQVYVRDVECSVP
                     RPLKELKGYDKVYLKKGETKRVRILLDEEAFAYYDVESHRFVVEKGTFEILAGPSSADL
                     PLKATVVL"
     CDS             7728..9932
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 84.6; E-value: 1.3e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg22_313"
                     /sec_met_domain="Fn3-like (E-value: 6.6e-26, bitscore:
                     84.6, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 1.2e-73, bitscore:
                     242.6, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 2.4e-51,
                     bitscore: 168.9, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIILMVCLWGLGNTFTSAQTTEKEKFISSLMKQMTLDEKIGQ
                     LAQCTYRGNFTGPDGGNIPKEEYVRQGRIGSMLNVIGVKDIRRYQELALQSRLRIPLIF
                     GLDVIHGYRTGFPLPLAEAASFDLAMIEEAARYNALESAADGLNWVFAPMVDISWDARW
                     GRVMEGAGEDPYYGSRVAEARVRGLQGDDLADTTTVMACMKHFAGYGAPIAGKEYNSVD
                     MSMGHFANFYMPPYKAAIKVGAATVMSAFNDFNNIPCTANDFLLNRLLREQWGFKGFVV
                     SDYNSVEELVNHRYAVDKKDAAAKALNAGLDMEMVSTCYLTYLKELVQEGKVKESVLDD
                     AVRRILEKKYELGLFEDPFRYCNPERAARILNAPEVRNASLRMAERSVVLLENRESVLP
                     LTAQTRKIALIGGLSKSQYDMAGAWAATTDRNKVVTLYDALVRKGLEVSYAEGYDMKSN
                     QLTGLQEALQAAEASDVIVVAVGERFGQSGEKASKVNIAIPEGQQKLVSELAKTGKPVI
                     ALVMCGRPVIFNEIREHADAVLCTWWLGSEAGNAICNVLWGEYNPSAKLPMTFPAHVGQ
                     IPIYYQNKSTGRPTALKQTYKASYIDASTEPAYPFGYGLSYTDFGYSDLKLLPGKAAGV
                     HTEVSVKVTNTGKCAGEEVVQLYVQDKVASVTRPIKELKGFRKIHLNVGESKTVAFQIT
                     DDALGFYDNEMNYMVEPGDFVFMVGGSSDDVQQITYNLKE"
     CDS             complement(10001..10726)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 75.5;
                     E-value: 1.7e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_314"
                     /sec_met_domain="Radical_SAM (E-value: 4.8e-30, bitscore:
                     99.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCPFRCLYCANPDTIDVKGG
                     TPTTPEEILQMAISQKAFFGKKGGITFSGGEPTLQAEALIPLFKELKANGIHICLDSNG
                     GIWNEKVEELFSLTDLVLLDIKQFNPERHRTLTGRSNEQTLRTAAWLEEHEHPFWLRYV
                     LVPGYSDSEEDTRLLGESLGKYQQIQRVEILPYHRLGVHKYEAMGWDYKLKEVKENTPE
                     QLERAEKLFKEYFTNVITN"
     CDS             complement(10728..12956)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: PFL_acetate1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_315"
                     /sec_met_domain="Gly_radical (E-value: 1.8e-45, bitscore:
                     148.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1169.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFTNGLWNKEINVSDFVSKNIAPYTGDASFLQGPTERTKR
                     IWDICLKALEEERNNNGVRSLDNTTVSTITSHKAGYIDKDNELIVGLQTDELLKRSIKP
                     FGGINVVAKACRENGVEVDDKVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGIDRLIEAKQEDLRNLTGPMTEARIRLREEVAEQIKALKDIK
                     VMGEYYGLDLSHPATSAQEAVQWVYMAYLAAIKEQDGAAMSLGNVSSFLDIFIEYDLAH
                     GKINETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTEAIGGRFNDGRVKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKDFCAKVSVDTSSIQYENDNLMREVRNC
                     DDYGIACCVSYQAIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKGIPVLTGETL
                     KFEEVMANYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMAFIDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAKVTARRNEIGLTEGFDTEGSFPCFGNNDDRVDHLGVDLVYYFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGPTPEERVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             13994..14869
                     /locus_tag="ctg22_316"
                     /transl_table=11
                     /translation="MVKATKDNRPFSSGVFDLEEFNIYTKVIDLPLDGIPTYLEEGING
                     VCTGGSALFNVFSNKRRVVKNDLITIFPYQLASITEISTDFAVIFFKVPKKLFMDTING
                     LGRLTLDYFFYMRKYYSSPLSEEEYKRFVHFCHILSCRVDLSCAFLRRESVMYLLRVYY
                     WDLYVGYKSNPKAMASVKFVRKEKQVFEFFYLVIEYHTISRDVAFYADKMCISPKYLTM
                     LITDNTGRSAKEWIVEYTILEIKVLLKDSNLEIKEVVSRTNFQSNSTMTRFFRKHTGTT
                     PSEYRERMFV"
     CDS             14911..15543
                     /locus_tag="ctg22_317"
                     /transl_table=11
                     /translation="MKEYLKIIDEIIALVGLHLIPKFVNLYQGQVDIRCEENDTGVLIN
                     IIVSLPDKNGLQALQNQVGMDSLQAKQILEGILKLEKMDSCKPLENRQLELKRIWLNKL
                     VSVLEEHMENTEFNVAMLCQLLGMNRKLLYRKIKQLTGVTPVSLIRRVRMIRAATLLLQ
                     GRFTVSEVMYMVGYSNPSYFSRCFMAEYNISPSQYAIIQKKTGGASE"
     CDS             complement(15582..17495)
                     /locus_tag="ctg22_318"
                     /transl_table=11
                     /translation="MKQNRLISIGAFILVLALSGLMTGCMEKDVYDPNREKEPLPDPDK
                     YFGFEMRSDVRLSVNYDIYGFTPLIEIYGENPMETVEGTPIKKEGIEALFKTYTDNSGK
                     YEGKMQLPTYLNKVYLYTATWGLPGCIELEIKDNAVIFDMSAKSNPKTKSVTRASSDVP
                     YLVNKSQNLYSLCYWGEGGQLNSQYMTKEKNIGNESILDLTDRMKTFFNKGGQDNSKLL
                     GNGKTINISIKEDNTALNLIFLNRSASYNNTFGYYFYKTGTSVDVDQVRKYIIFPNVSF
                     DWYGGQILILESGNKVRLLYFDEDGQAHDTFPAGYTVGWFLYADGFKNGYGNNLEDYLK
                     LPDLYNPYNSNLRTSNPQNNMSAFVSVKDQKSGKTILGAEDGVNQSYCDLLFYVDATPG
                     SSIDDPERPSIPDEGDKEEPKPDEDENVTGTLAFEDIWPSGGDYDMNDVIVEYERKVYF
                     DKKNIVTKIVDEFTPVHDGATYVNAFAYQIDAAQIGDKITLPEGAILEKQTSSIIVMSN
                     AKQNIGNKYVVTREFNGSFLKNQLLSYNPYIIVKYSQGEQNRTEVHLPKHKATAYANQS
                     LIGSNDDAYYIDRKGAYPFAIDIPMLGFTPVTERNRIDSQYPGFATWAKSMGNDCKDWY
                     KK"
     CDS             17802..18803
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: ACP_syn_III_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: Thiolase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ACP_syn_III"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_319"
                     /sec_met_domain="Thiolase_N (E-value: 6e-10, bitscore:
                     33.2, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III (E-value: 2.9e-32, bitscore:
                     104.8, seeds: 136, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III_C (E-value: 9.3e-33, bitscore:
                     106.7, seeds: 152, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKINAVITGVGGYVPDYILTNEEISKMVDTTDEWIMGRIGIKER
                     RILHEEGLGTSFMARKAVKQLMQRTKSNPDDIDLVIVATTTADYHFPSTASILCERVKL
                     KNAFAFDMQAVCSGFLYALETGANFIRSGKYKKVIVVGADKMSSVIDYTDRATCPIFGD
                     GAAAFMLEPTREDMGVMDAVLRTDGKGLPFLHIKAGGSVCAPSYYTLDNRMHYIYQEGR
                     TVFKYAVANMADACEAVMERNHLTKEDIDWVIPHQANMRIITAVSQRLGVSPEKVMVNI
                     ERYGNTSAGTLPLCVWDFEDKLKKGDKLIFTAFGAGFAWGAIYVKWGYDGKG"
     CDS             18945..20447
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gln-synt_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_320"
                     /sec_met_domain="Gln-synt_C (E-value: 4.2e-57, bitscore:
                     188.0, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQELSMSPNLLVAALQKPASEFTKADIVSYIKENDIRMVNFMYP
                     AADGRLKTLNFVINNEAYLDAILTCGERVDGSSLFPFIEAGSSDLYVVPRFRTAFIDPF
                     SELPTLSMLCSYFNKDGEPLESSPEYTLRKACQAFTTVTGMEFQAMGELEYYVISENDG
                     LFPATDQRGYHESAPYAKFNDFRTECMSYIAQAGGQIKYGHSEVGNFTLDDKIYEQNEI
                     EFLPVRAEEAADQLVIAKWVIRNLASQYGYNITFAPKITAGKAGSGLHIHMRIMKDGQN
                     QMLKDGALSETARKAIAGMMKLASSITAFGNTNPTSYFRLVPHQEAPTNICWGDRNRSV
                     LVRVPLGWSAKTDMCMLANPLETPSHYDTTQKQTVEMRSPDGSADLYQLIAGLAVACRY
                     GFEIDDALGIAEKTYVNVNIHKKENEDKLKQLEQLPDSCAASADCLERQRAVFEQYHVF
                     SPAMVDGVISKLRSYEDRTLRAEIQDSPEEMLKLVEKYFHCG"
     CDS             complement(20509..22203)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) B12-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_321"
                     /sec_met_domain="Radical_SAM (E-value: 4.9e-18, bitscore:
                     60.4, seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="B12-binding (E-value: 3.2e-11, bitscore:
                     37.7, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILWIDLNSSYAHSSLALPALHAQIAKNNSVKWEIVSATINENV
                     GMIVDEIYRHQPDIIAATTWLFNHEQLLHITARLKALLPNSCFILGGPEFLGNNEDFLH
                     KNPFIDCVFRGEGEEAFPQWLSCWNQPEKWNSIPGLCYMNPQKQYIDNGIARVLNFSRL
                     VPPENSSFFNWSKPFVQLETTRGCFNTCAFCVSGEEKPVRTLSIESIRERLQIIHSHGI
                     KNVRVLDRTFNYNPRRAKELLQLFLEFNPDICFHLEIHPALLSEELKNELKKLPKGLLH
                     LEAGIQSLREPVLQKSRRMGSLEDSLQGLRFLCSLPNMETHADLIAGLPLYRLSEIFED
                     VRTLAGYNAGEIQLESLKLLPGTEMRRRAEELGIRYSPLPPYEVLQTNEISVNELQTAR
                     QLSRLLDGFYNTTAWQAITRKLILDDNDFLRRFLEFLIDKNLIDQPMSLEKRGLVLYEF
                     CSMHYPAYKIMVTIAWIEAGMSLKKKPAEKVKTKRQMPPEYWEVIYGNYKESLRLCFLP
                     IDDNTQNGYWFGFESEIQKAEPVFKAKEIMERCQNTQSPQINTDKSS"
     CDS             22276..22401
                     /locus_tag="ctg22_322"
                     /transl_table=11
                     /translation="MSEIENSRVIGIECFLKDEIFFLYSYFYKVITGCLITGLIK"
     CDS             22659..22841
                     /locus_tag="ctg22_323"
                     /transl_table=11
                     /translation="MELNGYRLLLPEGTLEYFALVDVKESVNEVVIYLEEKNIVPEKYT
                     DQDTESKGFYDPVIVQ"
ORIGIN
        1 acaatggcat tgagcggcgt acggatttca tggctcatgt tggcgaggaa tgcggatttc
       61 agtttattcg actcttccgc acggttcttg gcggaaacca gttccgtctc catctttttc
      121 cgttcggtga taaccagcga agagcccacc agggtcagcg gcttattgtt ctcgtcgtag
      181 gtttctacgg cggcctgggc ctccacccag tcgaagtgtt tgtgtccgtc ggcatgattg
      241 atgacgcggt attcctcctt gactttctgg atacgtccct caatcaggtc tgtataggct
      301 tgtttcactt tttccaggtc ttccttgtgt attttggaga aatactggct gtcgggtacg
      361 gacagctgtt catcgtccat gataccggca ttattgctga gctctatcgg cttgttgaca
      421 tcgcagagta tggtgtgtgt ccggaggttc catttccatg gtacgatgtt ggcaacgtcg
      481 agtgccatgg aaagtttccg gtttgtcgac ctcaactgta tttgggtgtg gtgcaactcg
      541 gtgctgtcaa cgcagaagac gtgcatgtat tcgccattgt cgcttgcctt gactacaatg
      601 tcgtagaaag tgtctatctt cttgtaataa taggggaaag ttacggaacg tttctccttc
      661 aatgcaatat tcatgaaatg gaggaactcg ttcatggatt cgggaaataa ttcgcttccc
      721 cgcttgccga cagcctcttt gcgcatgata aatctgtctt cgaagaaatt gttgacatct
      781 atatataagg tgtcagtaat gcgccctttt tcatctttta taagtttctc atacatgtat
      841 aggatgggca tgttgtttat cagatttcgg tatttgagat tgctgtccag ttgttgctgc
      901 tgtaatcttt taattctact cagtgactgt aggcggagat attggaaaaa gaacagcaga
      961 gttatgattg cggcagtgat actgataatg acatattcgt acttctccca gaaggtggga
     1021 ggcatgttgt agaatatggt acccttgggg catagcttcg gattcaggtc acgctgcaga
     1081 agggatttat agttgaatac gggggctccg tcgtcgggat agtataacgg gatgttgcgt
     1141 gccggggtac catccaatat cttgtggatg gtttccagta gccgggcatt atatttctct
     1201 ttgttgtaaa tgtagccgcc tacaatcccc ccttcttctt caataccgat ggcccttagc
     1261 gaaaacaaag ggatgggggc ggtagagatg acccggtggg aattactcct catgatattg
     1321 tcatggggag agctcttgta cagccaggat gaaaagatga ctccggtagt atggggattc
     1381 acgtggttca gtatattgaa aaggctgtcc gttcggatgt ccttcgcact aaggaactgg
     1441 taatccaact ccggatactt ttcacggata atctcggaca agtcatagtc gttctgctgg
     1501 cagatgtatg tttcatcccc tatatacatg accttatcca ttttggggat gagttgcttc
     1561 atgagttgca ggttctcgtt caggtataca ctggattgca ttaaggtcag attgtacttc
     1621 ttctgtaggt cactgatggg aatacgctct gtgcggggca gggcgtgctc gcgtatcatt
     1681 gtttccttag gaccggtata atccctctca ccacataata tcatggggat atcgggccac
     1741 tgccggttca gttcatcgca catgatgaaa cttccgcatc cgataagcac gataagttta
     1801 gggttcttgt aactcttgaa caagctctct ttgaatgtct ccagtttatt ttcctcgtca
     1861 agtgtcagca ttttcatgtg tgcggtgtat actccgatgt ggctgttctg tgatgccatg
     1921 ttcacaatgg aggtgatgaa atcattactc cagggattgg cttctgtata agtgttgatt
     1981 atcagaatat cgtcgacgtc tgttgcggga gattttccat atagggtgtc tgtgcaggtg
     2041 aacgagcaga gtattgcaat tactgttccc agtatgtatt tcatatgcaa ttactgttcc
     2101 cagtatgtat ttcatatcct ttggaccgtt ttaatgtttg ctattgtgaa aattcttaca
     2161 aatgtagggg tttcccggtg gatagacaaa gaaaaagatg aatttaagcg ggatatggaa
     2221 aaacaaagcg gagcaacata ttgaaatgtt actccgcttc tcattgagat gttgaaaaat
     2281 gtgttttcag gagatttagt tgttttcttt tttaatgtct atggtcatga accgttcacc
     2341 gtcatataga cttttgacgc ggatgttcag tccttttttc tctttcagct gttccgctat
     2401 attgtccagc ttgaaggagg ccagtccggt gcccagcgtg agctggctgt cattgtaggc
     2461 attgtggcgg aattcgagat tgacgtaatc cggtttgtcg ttctcgccgg tggatgcttc
     2521 gttgatgacc aggttcagca tgtgcttctt atcttcgttg ttgctgtggt agaattgata
     2581 tttgatgttc agatactcgc ccgtaatcca taaatccgtg gcgttgatgt tgtcgtctcc
     2641 gatactgtct gccttttcgg caggcatgga gtagatgtct ttggtcagaa tgttttcgat
     2701 gtgctttatt tgggcattgt attcgtagcc tggaagtttc tcttccagtt cgcggaagta
     2761 gatgaaagcc ctctggccgt ctattacggc atagtcgtga acataggttg tgtcactggg
     2821 atatagttta ctgccttcgt ccagtgagaa atagtagtct tttccttcga tgacctttac
     2881 cgtacctacg gcgaacaaag tgtcatattt gtcatcccaa tcgtccaggc atgattgcaa
     2941 tacaatggca gtcaggaata aaagcatgga tgctgccaat gtcattctca gtttcttcat
     3001 aagtggtagg ttttagctct tttctgttta aaacttattt ttgtattcag aaaatgcggt
     3061 gaaaagctaa atactgcgta gtatactgtt aaagaaatga aagtatgatt ttcttctctg
     3121 cctgatgcag tatttttgcg ctgattgcat ttatagggta aacacgtgtt aaaagagaga
     3181 atggaagaac aggaattggc agaacgctgt aggcaaggag acaatcttgc ccgcaaagaa
     3241 ctgtatgagc gctatgcggg acgcatgctc agcgtatgcc tccgttatgc aggtgaccgg
     3301 gagactgccc aagacctgat gcatgacggt tttctgaaac tttttgattc tttcgataag
     3361 ttcacttggc ggggagaggg ttctctgcgg gcatggatgg aacgcgtaat ggtgaatacg
     3421 gtgttgcagt atttgcggaa aaatgatgtg atgaatcagt catcggcctt ggagaatgca
     3481 cccgaagctt atgaggaacc ggaaggttcg tcaatagatg tcattcctca aaaggtactg
     3541 atgcagttta tcagtgaatt gcctgccggc tatcgtaccg tattcaactt atatattttt
     3601 gaagagaaat cccataagga gattgctcga ctattgggaa ttaatgaaaa atcctctgcc
     3661 tcgcagttga cgcgtgctaa agcgacttta gcggcaaaag tacgtgagtg gatgaaaaga
     3721 aatgattaaa tgaaggaacg tatggaagat gaattgtggt tgaaaaagat aaaggacaag
     3781 ctggaagact attccgaacc gctgccggtt gccggatggg agcggttgga gaaggaattg
     3841 tccgtttccg gagctccgat aaccggaccg cataggatga tacctttccg tcgctgggcg
     3901 gtggctgcgg cagctgtgct gctggtggca gtatcgtccg tcagtctgtg gctgttgcag
     3961 agtccggtag ggaatgaaat gcggcatacg tcagtgcctg ctttggctgt ggctccggat
     4021 gtcttgccgg aacagacggt acctgctgta cggactaatc ccatagagcc tgcctatcgg
     4081 gcacatggaa atgcatcggc acccaatagg gaggcaagtc gccctttggt tgcacaacat
     4141 atcagaatat cggttgacga tgagcggcag gaggaaatgt tgccggttga aactgcaggt
     4201 gaggctgtcg gtattgggca gcaggcggaa gagccggtaa tggaagatac ggaccatgcg
     4261 accgcaatgc aggcagagga accggagaga acaaggaaag accgctatcg tccgtcaggc
     4321 cgggacaaac tgcatcttcc ggaaagaaac agttctggta gggatactaa aggatgggcg
     4381 gttggcttgt ccgtaggaaa tacgggaggt ttttcattgg cgaatgaagg ggaagcgaat
     4441 gtgatgtcgg actacatgcc tggaagtcct atttatggcg gtaacgtaga tttatcctct
     4501 acggccaatg gcattgttac tattcccgac gggcaggaac tggtttttaa ggatggtatg
     4561 ccctatctgc aaagacgcga aaagaaaatt gcggatatag accataaaca accgctcagt
     4621 ttcggtgttt cggtgcggaa aaacttggcg aagggtttct ctgtggaaag cgggctgacg
     4681 tatacctatc ttgcttctga cgtaaggtat gagggcagct cggaaaagat aagccagaag
     4741 ctgcattata ttggcattcc ggtacgggcc aactggaact ttgtggatgc aaagaacttt
     4801 acgatgtacg tttcggcggg gggtgccatt gaaaaatgtg tgtatggcaa gattggtact
     4861 gagagtgaga ctgtgaaacc ggtacagctt tctgtcatgg gtgctgtcgg tgcccagtat
     4921 aacataagca atagggtggg cctgtatgtg gaaccgggag tatcttattt ctttgatgac
     4981 ggttcgtcga tacagactat acgcaaggag aacccgtgta actttacgtt gcaggccggt
     5041 atacgtctta cttattgata gcaggacaga catgtttttg tccactttct tgtagattca
     5101 gaattttctt aataactttc ggccgtgttt cttcgttggt ggatgaaggg acacggtttt
     5161 ttattgattg agaagaaaga aagtaggtcg ggacatgccc ggcaatataa caaacacgta
     5221 gtaaaataga caaaatgaag attaaaaaga aagtagcctt aagcgggcta ttgctttgtt
     5281 gtgcaatcac ggcaaaagca caagtgtgta ttactcccca ggtggagcag cgtgccaggg
     5341 agttggtttc tcaaatgacg ctggaagaaa aaatcgatta catttccggt cccaaatctt
     5401 tttatatccg ggctgtaccc cggcttggca tacccgaaat caggatggcc gatggtccgc
     5461 aaggcatacg taacaatact caaagtacct tgtatccttg tggcatcttg tcggcttcga
     5521 catggaaccg taagttggct agagagctgg gacatggttt ggcccgggat gcaaaggccc
     5581 gtggggtaag tattctgttg gggcctggag tcaatatcta ccgctctcct ctatgcgggc
     5641 gaaactatga gtattttggt gaagaccctt atttaacggg cgaaactgct aaagaatata
     5701 tcttgggagt gcaggaagag ggagttatgg ctacggtgaa gcattttgcg gccaataacc
     5761 aggagtggag cagacatcat gccagctcag atgtggatga acgcacgctg caggaaattt
     5821 attttcccgc gttccgaaaa gctgtgcagg aagcaggagt aggggcggtt atggatagct
     5881 ataatccgct gaacggggta catgccaccg aaaacagctg gctgaacatt gatgtattac
     5941 gcaagcagtg gggatttaaa ggtatcctga tgtctgactg gacatctgta tattccggtg
     6001 tgggagccgc taatggaggg ttggatttgg aaatgcccgt cggtaaattc atgaccaggg
     6061 aaattcttat tccggcaata gagaatggta tcgtgaagga agagaccatt gacgccaaag
     6121 tccggcatat actccagaca ttgattgctt ttggagcact tgatactccg agagaagata
     6181 aatctatcga taaagacaat gcacagtcta aggaaattgc acttgacttg gcgagagaag
     6241 gagtagtctt attgaaaaat gataacggta cgttgcctta ccggaacggt agaacattgg
     6301 taatcgggcc taatgccgat attattccca caggaggagg aagcggattt gtcacccctt
     6361 attcggtagt gtcactctat gacggtatgg ttcagttgaa gggcggcaga cagatagagc
     6421 tgctgtctga cagcattctt tataaggata tgtcccaaca gatttatacg gatggcagtt
     6481 ttacgcaaaa cggttttaag ggcgaatatt ataatactcg taatcttacc ggagaactct
     6541 ttcaagctgc catagagcct gccatagacc atgcctggaa atacggtgca ccgttcgacg
     6601 gcatgccggt agatcagttt tctgcccgtt ggacgggagt ttacaaggct gacaaggatg
     6661 gaactgtcaa gttccagctg gctggcgatg acggataccg tctgtttgta aacgataagc
     6721 tgattaccgg agattggggg aaccattcat tcagtacccg cagtgcattt atgcaggtca
     6781 gtgcagggga gatataccgg ttgcgtattg aatattttga taatgtgggt gaggcgactg
     6841 tcagtttcca ggcaggaatg atggatgagg agcgtttggc ctcttcactg aagcatgcca
     6901 ggaatgttat tgtatgtgcc gggttcaaca gcagtacaga aggtgaaggg ttcgaccgtc
     6961 cgtttgcatt gtcatacggg caggaatatc tcattaataa agtggcttca cttcatgata
     7021 atgtggctgt ggtggtgaat gccggaggtg gaatagattt ccgcaattgg gggcagagtg
     7081 tacaagctat tttgatggca tggtatccgg ggcaggaggg tggaaaggcc cttgccgaaa
     7141 tcattacggg caagctttcg ccaagtggca aactaccagt cagcatcgag gaaaaatggg
     7201 aagataatcc ggtatatggt aattattatg acaatcgcaa tgtacctcat aaacgggtgc
     7261 agtatgccga aggtgttttc gtaggttata ggggatatga ccggaacgga aagcaaccgc
     7321 tctatccttt cgggtatgga ctgtcataca gtagttttga atatagtaat ctgagtgttg
     7381 agaagacggg gggaagccgg gttacggtaa gctttgacat caagaatacc ggaaagatgg
     7441 atgctgcgga agcggctcag gtatatgtgc gggatgtgga atgttctgtt ccgcgtccat
     7501 tgaaggagtt gaaaggctac gataaggttt acttgaagaa gggtgaaacc aagcgcgttc
     7561 ggatattgct ggatgaggaa gcctttgcct actatgatgt ggaatcacat cggtttgtag
     7621 tggaaaaggg gacttttgag attctggcag gtccttcttc agctgattta ccattgaagg
     7681 caactgttgt tttatgataa aataaatatc aaaacaagaa tggcagtatg aaaaagataa
     7741 taatactgat ggtttgtctg tggggacttg gtaacacctt tacctcggca caaactacgg
     7801 agaaggagaa attcatctca agcttgatga agcagatgac gctggatgaa aagataggcc
     7861 agcttgcaca atgcacctac cgagggaatt ttaccggacc cgacggtgga aatattccta
     7921 aagaagagta tgtccggcaa ggcagaatag gctctatgct gaatgtgata ggagtaaagg
     7981 atatacgccg ttatcaagag cttgctttgc aatcgcgttt gcgcattcct ttaattttcg
     8041 gactggatgt tatccacggc tatcgtaccg gatttccgct tccgcttgcc gaggctgcaa
     8101 gtttcgattt ggccatgatt gaggaagctg cacgctacaa tgctttggaa agtgccgctg
     8161 atggtttgaa ctgggttttt gccccgatgg tggatatttc gtgggacgca cgttggggac
     8221 gcgtcatgga aggggccggt gaggaccctt attatggttc tcgggtagcg gaggcgcgtg
     8281 tcagaggctt gcaaggagac gatttggcag acacgacgac tgtcatggca tgtatgaaac
     8341 attttgccgg atatggtgca ccgatagcag gaaaggagta taatagtgtg gatatgtcaa
     8401 tgggccactt tgccaatttt tatatgcctc cctataaggc ggccataaag gtaggagcag
     8461 ctaccgtgat gagtgctttc aatgatttta ataatattcc ttgtactgcc aatgatttct
     8521 tgctcaaccg gctattgaga gagcagtggg gatttaaggg atttgttgtg tccgattata
     8581 attcggtaga ggaattggtg aaccaccgtt atgctgttga caagaaagat gccgcagcca
     8641 aagcgctgaa tgctggtctg gacatggaga tggtaagtac ctgctacttg acttatctga
     8701 aggagcttgt tcaagaaggg aaagtaaagg agagtgtgct tgatgatgca gtacggcgta
     8761 tattggagaa gaaatatgag ttgggattgt ttgaggaccc ttttcgctac tgtaatccgg
     8821 aaagagcggc cagaatactc aatgcgcccg aagtccgtaa tgcttcgctc cgtatggccg
     8881 agcgttccgt tgtattgctg gagaataggg aatctgtgct tccgttgacg gcacagacga
     8941 ggaagatagc cttgatagga ggactctcaa aatcccagta cgatatggca ggtgcttggg
     9001 ctgccactac ggaccggaac aaagtggtga ccttatatga tgcattggtc cggaaaggac
     9061 tggaggtgag ctatgctgaa ggctatgata tgaagagcaa tcagttgacc ggattgcagg
     9121 aagcattaca ggctgctgag gcttcggatg tcattgttgt ggcggtaggc gagagattcg
     9181 gtcagagtgg cgagaaggct tccaaagtga atatagccat acccgagggg cagcagaagc
     9241 tggtgtcgga actggcaaag actggaaaac ctgtcattgc tcttgtcatg tgtgggcgtc
     9301 cggtaatctt caatgagata agggaacatg ctgatgcggt actgtgtact tggtggctgg
     9361 gaagtgaggc cggcaatgcc atatgcaatg tgttgtgggg agagtataat ccttcggcta
     9421 aattgcccat gacatttcct gcacacgtag gacagattcc catttattat cagaataaga
     9481 gcaccggccg ccctaccgca ttgaaacaga cctataaggc atcttatatc gatgcttcca
     9541 ctgagcctgc ctatcctttc ggatatgggc tttcgtacac ggattttgga tattctgatt
     9601 tgaaactgct gccgggcaag gctgcaggcg tccatacgga ggtgtcggta aaagtgacta
     9661 ataccggtaa gtgtgcagga gaggaagtag ttcaattgta tgtgcaggat aaggtagcct
     9721 ctgttacgcg tccgataaag gaattgaagg gcttcaggaa aattcatctg aatgtgggtg
     9781 aaagcaaaac tgtagctttt cagataactg acgatgcact gggattctat gacaatgaga
     9841 tgaattatat ggtagaacct ggtgatttcg tctttatggt gggtggcagt agtgatgatg
     9901 tacagcagat tacctataac ttgaaagaat aggattctta ccctataaat gaaaagcaag
     9961 gctgtctgga atcatatccg gacagccttg cttttctgtt ttagttggtt atcacattcg
    10021 tgaaatactc tttgaacagt ttttctgccc gttccagttg ttccggagta ttttccttca
    10081 cttctttcaa tttgtaatcc catcccatgg cttcgtattt gtgaacaccc agacggtgat
    10141 aaggaagtat ttccacccgt tgtatctgct ggtatttgcc aagactttca cccagcaggc
    10201 gggtgtcttc ttccgaatcg ctgtaaccgg ggaccagtac atagcgcagc cagaaggggt
    10261 gttcatgttc ttcgagccag gcagcggtgc ggagtgtctg ttcgttgctt cgtcccgtca
    10321 gcgtacggtg gcgttcggga ttgaattgct tgatgtccag cagcacgagg tcagtcaggc
    10381 taaagagctc ttccaccttt tcattccaga tgcctccgtt actgtccaga cagatatgga
    10441 tgccgttcgc cttcagctcc ttgaaaagag gaatcagcgc ttctgcttgc agggtaggct
    10501 caccgccgga gaaagtaata cctcctttct tcccgaagaa tgccttttgg ctgatagcca
    10561 tttgcagaat ctcttccgga gtggtgggag tgcctccttt tacatcaatc gtatccggat
    10621 tggcacaata cagacaacgg aacggacatc cttgcaggaa aacgacgagc cggagacccg
    10681 gcccgtcgaa tgttcccata ctttcgtagg agtgtacatt tatcatatta cattctttcg
    10741 tggaatgaac ggctgatgac ttccaactga tgctcgcggc tcaacttcac gaagttcacg
    10801 gcatagccgg aaacgcggat ggtgagttgc ggatactttt caggatgttc catggcatct
    10861 tccagcattt cgcggttcag tacgtttacg ttcaagtggt gggcaccttt ggtgaagtag
    10921 ccgtccatca tggttaccag gttctctaca cgttcttccg gtgtcgggcc cagtgatttg
    10981 ggaacaatgg agaacgtatt gctgatgccg tcctgcgagt cgcggtagcg caatttggct
    11041 acggagctca aggaagcgat ggcaccgttc ttgtcacgtc cgtgcattgg gttggcaccc
    11101 ggagcaaagg caacaccttt ggcgcgtccg tccggagtgg caccggtctt cttgccgtac
    11161 atcacgttgg aggtgatagt cagcaaggaa agggtgggac gggcattctt gtagacaggc
    11221 agctttttca gttcttcgct gaaatagtaa acgaggtcta ctcccaggtg gtccacacgg
    11281 tcgtcattat tgccgaagca ggggaatgaa ccttcagtgt cgaaaccttc ggtcaggccg
    11341 atttcgttgc ggcgtgcagt gactttggcg tatttgatgg cagacagtga gtctatggcg
    11401 atggaaaggc cggcaacacc gtatgccaga ttgatgcgtg ggtcggtatc gatgaatgcc
    11461 atctgggctt tctcataata atacttatca tgcatgtagt ggatgatatt catggcctcg
    11521 ttgtagacac gggctatttc agtcagtacc ttcttgtagt tggccataac ttcctcaaac
    11581 ttcaatgtct caccggtcaa tacgggaata cctttcacca tgacagttcc ggtattttcg
    11641 caacgtccac cgttgatggc gagcagcagg gccttggcaa ggttggcacg tgcgccgaag
    11701 aactggattt gtttgccgat ggcttggtag gatacacagc aggcgatgcc gtagtcgtcg
    11761 cagttgcgca cttcacgcat caggttgtcg ttttcgtact ggatggagct ggtatctaca
    11821 gaaactttgg cgcagaaatc cttgaagcct tccggcagtt cgggactcca caatacggtc
    11881 aagttcggtt ccggagaagg accgaggttg tatagcgtct gcaaaaagcg gaaagaagtc
    11941 ttggtgacct tcacgcgtcc gtcattgaag cgtcctccga tggcttcggt cacccaagtc
    12001 gggtcaccgg caaagatatc attgtatgat tgcatacgca gatggcgtac catgcgcagc
    12061 ttgatgacga actggtctat cagttcctgt gcaaacgtct cattgatttt tccgtgagcc
    12121 agatcgtatt caatgaatat atcgaggaac gaagatacgt tacccagtga catggctgct
    12181 ccgtcctgct ctttgatggc agcaagatat gccatgtata cccattgcac ggcctcttga
    12241 gctgatgtag ccggatggct gaggtcgagt ccgtaatatt cgcccataac cttgatgtcc
    12301 ttcaaagctt tgatttgttc tgccacttct tcgcgtagac ggatgcgtgc ttcggtcatc
    12361 gggccggtga ggttgcgcaa gtcctcctgc ttggcttcaa tcagacggtc gatgccgtag
    12421 agagccaatc ggcggtagtc gccgatgata cgtccgcggg catagttgtc gggcaatccg
    12481 gtaaggaatc ccagtgagcg gaaggaacgg atttcttcgg tatatacatc gaatacgccg
    12541 tcgttatgtg ttttgcggta atgggtgaag atgtctttta ctttatcgtc cacttccact
    12601 ccgttttcac ggcatgcttt tgctaccacg ttgatgcctc cgaaaggttt gatggatcgt
    12661 ttcaacagtt catcagtctg caaaccgaca ataagttcat tgtccttatc aatatacccg
    12721 gctttatgag aagtgatggt agatacggtg gtattgtcca gtgaacggac gccattgttg
    12781 ttcctttctt cttcgagagc cttcagacag atgtcccaga tacgtttggt acgttcggta
    12841 ggtccctgca ggaaagatgc atctccggta tagggtgcga tgtttttact gacgaaatca
    12901 ctgacattga tttctttatt ccaaagccca ttggtaaagg ttttgttcaa ttccataaaa
    12961 tttgtttttg ttagtaggtt agataatgtt atcctttaga gcgcgcaaaa atactgaata
    13021 aattccgtaa ttttataaga gatacttctc tttttatgtt gaacagcata aaataactat
    13081 tattaggtag tgaatgtccg ggggagtaga gatgttaata ctttctttat atgtggttta
    13141 tgaattgaaa caagaaccga ataataatct gcattattta caaatgatgt aggtttaagg
    13201 aacagtcgta ttctgaacct aattcagtcg tatagtgaat gccattcagt cgtatactga
    13261 atagggttca atcgtatact gaatgtggct ctttgtaaat atactgatag ccagtaagtt
    13321 ataaaactct gtcttgccct tgataaattt caacaaatag cctaaatgcc gttatgttcg
    13381 ttccgtagtg ggtataaaca agaattttgg tataattgct ctgtttttgt gcagaaaagt
    13441 ttgtagaata aaaaatgatt tgtatctttg caccgcttta aaagaaaagc acttctgaaa
    13501 aagaagtttt ggagaggtgg cagagtggtc gattgcggcg gtcttgaaaa ccgttgtgct
    13561 gcgaggcacc cggggttcga atccctgtct ctccgctgnn nnnnnnnnnn nnnnnnnnnn
    13621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13681 nnnnnnnnnn nnnnnggcag agtggtcgat tgcggcggtc ttgaaaaccg ttgtgctgcg
    13741 aggcacccgg ggttcgaatc cctgtctctc cgctgaacta actggataat gaataggtaa
    13801 gtctcataaa ttcaacgatt tgtgggactt tttttattcc attatctctg ccctatcgga
    13861 tattatttag ccctttatag aataagaatt tatactttag ttttgactga acttcagtat
    13921 atatgtgcaa ttttagaaca aataatctaa aaatgatttt tttttgtaac ttagcataat
    13981 atttaaaaca aatatggtaa aagctacaaa agataatagg cctttttcaa gtggtgtgtt
    14041 tgatttagag gagttcaata tttatacaaa ggtaattgat ttgcctcttg acgggattcc
    14101 gacatatcta gaagaaggga taaatggagt ttgtaccgga ggctctgctc tttttaatgt
    14161 gttttctaat aaacgcaggg ttgtgaagaa tgatttgata actatttttc cttatcagtt
    14221 ggcaagtata accgaaatca gtacagactt tgccgttatt ttctttaaag taccaaagaa
    14281 attgtttatg gataccatta atgggctggg taggcttaca cttgactatt ttttctatat
    14341 gaggaaatat tatagctctc cgctcagtga agaagagtat aagcgctttg ttcatttctg
    14401 tcatatattg tcatgccgtg tagatttatc ttgtgccttt cttaggaggg aatcggtgat
    14461 gtatttattg agggtttatt attgggactt gtatgtgggc tataagagta accccaaggc
    14521 tatggcttcc gtgaagtttg tacgtaaaga gaagcaggtt tttgaattct tttatttggt
    14581 tatagagtat catactataa gtcgtgatgt ggcattttat gcagataaga tgtgtatctc
    14641 acctaaatat ctgacaatgt taataacaga taatactggt cgttcggcta aagagtggat
    14701 tgtggaatat accatacttg agataaaagt cttattgaaa gactccaatc ttgaaataaa
    14761 ggaagtggtt tcacgaacta attttcaatc gaattctacg atgacacgtt tttttcgtaa
    14821 gcatacaggc actactccgt cagaataccg tgagagaatg tttgtctgat atttggataa
    14881 tttgtactta taccaaaagg caagaaagat atgaaagaat atcttaaaat aatagatgaa
    14941 ataatcgctc ttgtggggtt acatttaatt cccaaatttg ttaatctata tcaaggccag
    15001 gttgacataa gatgtgagga aaatgatact ggagtcttaa ttaatattat tgtgtcttta
    15061 ccagataaaa atggactgca ggctttgcaa aatcaagttg gtatggactc actacaagcc
    15121 aaacagatct tagaaggaat attaaaattg gagaaaatgg attcatgcaa accattggaa
    15181 aacagacaac tggaattgaa acgaatttgg cttaacaagc ttgtttcagt gttggaagag
    15241 catatggaaa atacagagtt taatgttgct atgctctgtc aactgttggg aatgaatcga
    15301 aaactgttgt atcgaaagat taaacagttg acgggggtta ctccagtaag ccttattcgg
    15361 cgtgttagga tgataagagc cgctacactt ttattacaag gcagattcac tgtatcggaa
    15421 gtaatgtata tggtaggcta ttccaatcct tcttattttt ccaggtgttt catggcagaa
    15481 tataatattt ctccaagtca atatgcaata attcaaaaaa aaacaggtgg agcgtccgaa
    15541 taagggggca ctccacacat gattcattgt cttttgttct gttatttttt ataccaatcc
    15601 ttacagtcat ttcccattga ttttgcccat gtagcaaaac cgggatattg gctgtcaatt
    15661 ctgttccttt ctgttaccgg ggtaaaccct agcatcggta tatcgatagc aaatggatat
    15721 gctcctttac ggtcgatata gtaagcatca tcattgctgc caatcaatga ctgattggca
    15781 taagctgtag ctttgtgttt gggcagatga acctctgtgc gattctgttc tccttgtgaa
    15841 tattttacga tgatgtatgg attataggac aatagctgat tctttaggaa agaaccgttg
    15901 aattctctgg tgactacata tttattgcct atattctgtt tggcattgga cattacgata
    15961 atggacgaag tctgtttttc caatattgca ccttccggca aagtgatttt atcgccaatt
    16021 tgtgctgcat ctatctgata ggcaaatgcg ttaacatatg tagcgccatc atgtaccgga
    16081 gtgaattcgt caacgatctt cgttactata ttctttttgt cgaaatagac tttgcgttcg
    16141 tattctacaa ttacgtcatt catgtcataa tcgccaccgg aaggccaaat atcttcgaat
    16201 gccagtgtgc cggtaacatt ttcatcttca tcgggtttgg gttcttcttt atcaccttca
    16261 tcgggaatag acggcctttc aggatcgtca atagaacttc ccggagtagc atctacataa
    16321 aataaaaggt cacagtagct ttgatttaca ccatcttctg ctccaagaat cgtcttgccg
    16381 cttttttggt ctttaacaga gacaaaggcc gacatgttgt tttggggatt ggaagtgcga
    16441 agatttgaat tgtatggatt atataaatca ggcaatttaa gataatcttc taaattattt
    16501 ccataaccgt tcttaaaacc gtcggcataa agaaaccagc ctactgtata tcctgctggg
    16561 aatgtatcat gggcttggcc gtcttcatcg aagtaaagca gacgaacttt attcccggat
    16621 tctaaaatca atatttggcc gccataccag tcaaaagaca cattggggaa tataatgtat
    16681 ttcctcactt ggtctacatc gacggacgtt ccggttttat aaaaataata tccgaaagta
    16741 ttgttataac ttgcacttcg attgagaaaa atgagattca atgcggtgtt gtcctccttt
    16801 atcgaaatat tgatagtttt tccattacca agtaattttg aattgtcttg tcctccttta
    16861 ttgaagaatg ttttcatccg gtctgtcaaa tccaaaatac tttcattacc aatatttttt
    16921 tcctttgtca tatattggct gttcagctga cctccttctc cccaatagca cagtgagtat
    16981 agattttggg atttgtttac taaataaggt acatcagacg aagcgcgagt gacagacttt
    17041 gttttaggat ttgattttgc cgacatgtca aaaatgacag cattgtcttt aatttcaagt
    17101 tctatgcatc ccggcaatcc ccatgtcgca gtatataaat aaactttatt aagataggta
    17161 ggaagctgca tttttccctc atacttaccg ctgttgtcgg tataggtttt gaacaaggct
    17221 tctataccct ctttctttat cggcgtacct tccactgttt ccatcggatt ttcaccgtaa
    17281 atttctatca aaggagtaaa cccgtaaatg tcatagttga cagaaagccg gacatcactg
    17341 cgcatctcaa agccgaaata tttatccggg tcaggaagag gttctttttc acgattcggg
    17401 tcgtatacgt ctttctccat acaacctgtc ataaggcctg aaagtgcaag cactaaaatg
    17461 aaagccccaa tgctaattaa gcggttttgt ttcataagat ataaaaatgt tatgttaatt
    17521 ttatttgtat gtatttttga ttagttactt gctctttaaa tacccgatac attttattat
    17581 gcaaatttag tctgtattgc tcaaactcat tgatacaaaa ttgacaaaag aatgatagaa
    17641 aaaggacagt tgattttttt tgtatatcca tgtgatagtt tgtcgggagt gtctttttgt
    17701 tcttccttta ttggatttta ccctcttttc agtatatttg cgctcggcgt tttaagaata
    17761 ttatctttga gccgattcca atactaaact agatagaatt aatggagaaa ataaatgcag
    17821 taattacggg agtgggaggg tatgttcctg actatattct gaccaatgaa gaaatatcca
    17881 aaatggtaga tacgacagat gagtggataa tggggcgtat cggtataaag gaaagacgta
    17941 tcttgcacga agaaggattg gggacttcgt ttatggcccg taaagctgta aaacaattaa
    18001 tgcaacgtac aaaatctaat cctgatgata ttgatttggt gattgtggcc actacaacgg
    18061 ccgattatca ttttccttca acagcatcca tattatgtga gagagtaaag cttaagaatg
    18121 cttttgcttt tgatatgcag gctgtttgta gtggcttttt gtatgcattg gaaactggag
    18181 ccaattttat ccgttcggga aaatacaaga aggtcattgt agtaggggct gataaaatgt
    18241 cgtcggtgat tgattatacc gatcgtgcca cttgtccgat ttttggtgac ggtgctgccg
    18301 ctttcatgct ggaacccacc cgggaagata tgggagtaat ggatgccgta ttgagaacag
    18361 acgggaaagg tctgcccttt ttacatatca aagcaggagg ttccgtatgt gctccatctt
    18421 actatacact ggacaatcgg atgcattata tttatcagga aggacgtaca gtctttaaat
    18481 atgctgtggc caatatggcg gatgcttgtg aggcggtcat ggagaggaat cacttgacga
    18541 aggaggacat tgactgggtg attccccatc aggcaaacat gcgtataatt actgcagttt
    18601 cgcaacgctt gggagtatct cccgaaaagg taatggtcaa tatagaacgg tatggaaata
    18661 caagtgccgg cacgcttccg ttgtgtgtat gggatttcga ggataagctt aaaaaggggg
    18721 ataaactgat ttttacagca ttcggagcag gatttgcctg gggagctatt tacgtgaagt
    18781 ggggatacga cggaaaaggt tgaggctcac tgataagatt taggttgttt gttttttttc
    18841 tgatacaact tttagtatct ttgcgaaaca gcagtttttt attgtgacag aaaattgcat
    18901 gtgttttgtt aaccatatag aaaactaaaa acaatcagcg tattatgaac caggaattat
    18961 ccatgagccc caatctattg gtggctgccc ttcaaaaacc ggcttccgaa tttacgaaag
    19021 cagacattgt ttcctatata aaggagaacg acattcgtat ggtgaacttc atgtatcctg
    19081 cggcagacgg gagactgaag acactgaact ttgtcatcaa taatgaagca taccttgatg
    19141 ccatacttac atgtggtgaa cgcgtagatg gttccagctt gtttccgttt atagaggccg
    19201 gtagcagtga tttgtatgta gtgccgcgtt tccggaccgc ttttatagac cctttttctg
    19261 aattgcccac actgtcaatg ctctgttctt atttcaataa ggatggtgaa ccgctggaaa
    19321 gttctccgga atataccctg cgtaaggcat gtcaggcatt cactacggtt acggggatgg
    19381 aatttcaggc tatgggagaa ttggaatatt atgtcatttc tgaaaatgac ggattgttcc
    19441 cggctaccga ccagcgtggt tatcacgaat cggcccctta tgccaagttc aatgatttcc
    19501 gtacggaatg tatgtcatat attgcgcagg caggcggaca gataaagtat gggcattctg
    19561 aagtcggtaa ttttacgctg gacgataaga tttatgagca gaatgaaata gaattcctgc
    19621 cggtgcgtgc cgaggaggct gctgaccaac tggtgatagc aaaatgggtt attcgtaatc
    19681 tggctagcca gtatggatat aacattactt ttgcaccgaa aatcacggca ggaaaagccg
    19741 gttccggatt acatatacat atgcgtatca tgaaggacgg gcagaaccag atgctgaaag
    19801 atggggcact ttctgaaaca gcccgtaagg ccattgcggg catgatgaag ctggcttctt
    19861 ccattacagc tttcggtaat acaaatccta cttcctattt tcgtctggtt cctcatcagg
    19921 aagcaccgac caacatttgc tggggcgacc gcaaccgttc ggtattggta cgcgttccgt
    19981 tgggctggtc ggcaaaaacg gatatgtgca tgttggcaaa tccgttggag accccaagtc
    20041 attatgatac tacacagaaa cagacggtgg aaatgcgttc gcctgacggt tcggccgatt
    20101 tgtatcaatt gattgccgga cttgctgtag cttgccgtta tggatttgag atagacgatg
    20161 ctttaggaat tgcagaaaaa acatatgtca atgtaaatat ccacaagaaa gaaaatgaag
    20221 ataagttgaa acaactggaa cagcttcctg atagttgtgc cgcttctgcc gattgtttgg
    20281 aaagacagcg tgctgtcttt gagcaatatc atgtgttcag tcctgcaatg gttgatgggg
    20341 ttatttccaa actgcgttct tacgaggata gaaccttgcg tgcagagata caagacagtc
    20401 cggaggagat gctgaaactg gtcgagaagt atttccactg cggataggag aagaaatgag
    20461 ggcataactc accgcaggtt acacagattg ctatagaatt tctgataatc aagaactttt
    20521 atctgtgtta atctgcggtg attgtgtatt ttgacacctc tccattattt ctttggcttt
    20581 gaatactggt tctgcttttt gtatttccga ttcgaagccg aaccaataac cattttgggt
    20641 attgtcgtca atgggtagaa aacataagcg gaggctttct ttgtagtttc catagatgac
    20701 ttcccaatat tccggtggca tctggcgctt ggtcttgact ttctctgctg gttttttctt
    20761 taatgacatg cctgcctcta tccaggcaat ggtgaccatg attttatagg ccggataatg
    20821 catactgcag aattcataga gtacgaggcc tcgcttttcc aggctcatgg gctggtctat
    20881 aagattttta tcgattaaaa attccagaaa gcgacgtagg aagtcgttgt catccagaat
    20941 cagcttgcgg gtgatggctt gccaagcagt tgtgttatag aatccatcca gaagacgtga
    21001 cagttgccgg gctgtttgaa gctcgttgac actgatttca tttgtttgaa gcacttcata
    21061 aggggggaga ggagaatatc ggatgcctag ttcttccgcc cttcttctca tttctgtgcc
    21121 gggaagtaac ttcagggatt caagctgtat ctcgccggca ttgtatccgg caagtgtacg
    21181 cacatcttca aatatttcgg ataggcggta tagaggcaag ccggcaatga ggtcggcgtg
    21241 tgtttccata ttgggtaggg aacataggaa acgaagacct tgcagtgagt cctccaggct
    21301 tcccatccga cggcttttct ggaggaccgg ttcgcgcagg ctttgaatac cggcctcgag
    21361 atggagcaat cctttaggta gctttttcaa ttcatttttc agctcttcgg ataatagtgc
    21421 agggtgtatt tctaagtgaa agcatatgtc cgggttgaat tccaggaaaa gttgcagtaa
    21481 ttctttagca cggcgcggat tataattaaa ggtccggtcg aggacgcgta cgttttttat
    21541 tccatgactg tggataattt gaaggcgttc acggatactt tcaatggaca gtgtgcgcac
    21601 cggtttttct tcaccgctga cgcagaatgc gcatgtgttg aaacagcctc gggtagtctc
    21661 cagttgtacg aatggtttgc tccaattgaa gaaactgctg ttttccggtg gtacgagccg
    21721 ggaaaagtta agtacacggg ctatgccgtt gtctatatat tgcttttgag gattcatata
    21781 gcagagtccc ggaatactgt tccatttttc cggctggttc cagcaagaca gccattgggg
    21841 gaatgcttct tctccctctc ccctgaatac gcagtcgatg aaagggtttt tatgcagaaa
    21901 gtcttcattg tttcctaaga attcaggtcc gcccaagatg aagcagctat tgggaagcaa
    21961 tgcttttaat ctcgctgtta tgtgcaacag ttgttcgtgg ttgaacaacc atgttgttgc
    22021 ggcaatgatg tcgggttggt gccggtatat ttcgtcgaca atcattccta cgttttcatt
    22081 gatggtggca gatacgattt cccattttac ggaattgttc tttgctattt gtgcgtgcag
    22141 tgcagggagt gccaacgaag agtgtgcata cgagctattg aggtctatcc agagaatttt
    22201 catatttgat tgaatttcat ctttgcaaag ataactgatt ttgcttttcg tataaacaaa
    22261 aagggttata tttgcatgtc ggaaatcgaa aatagtagag ttattggtat agaatgtttt
    22321 ttgaaagatg aaatattctt tttgtattct tatttctata aggtgataac gggttgtctt
    22381 atcactggct tgataaagta aggaaggaag tactattaag tgtgattgat acagaatgca
    22441 aaatatcgga ataagtttcc agctattttg aacattttga gaaagtaaac tcttttgtac
    22501 aaggactggt ttaggtaatt gattccttcc tatgatgtag ggatactctg tgaggagtat
    22561 ccctacaatt ttttacattg attccacgtt gcgggtcaat gtaaaaacct gaggggtaaa
    22621 tttataaatt attatctttg tctccaaatt catagcttat ggagttaaac ggttatcgcc
    22681 ttcttcttcc tgaaggcact ttagagtact ttgctcttgt tgatgtgaag gaaagcgtaa
    22741 atgaagttgt gatctacctt gaggaaaaaa atatcgttcc tgagaagtat acagatcagg
    22801 atactgagag taaaggcttt tatgatcctg ttattgttca gga
//
