LOCUS       c00006_gnlPro..        16657 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DIFIJOHI_6.
ACCESSION   c00006_gnlPro..
VERSION     c00006_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 14:11:45
            Original ID  :: gnl|Prokka|DIFIJOHI_6
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16657
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..96)
                     /locus_tag="ctg6_1"
                     /transl_table=11
                     /translation="MKYSKKQYNYYSDDERMSYIREYLSSPESKSE"
     protocluster    1..16657
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3099:6657](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3100..6657
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16657
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16657
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(527..1681)
                     /locus_tag="ctg6_2"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDWKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1888..3066
                     /locus_tag="ctg6_3"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLIDQVFKHPEWS
                     KELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLWKDHKVHKGD
                     KNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGFLY"
     CDS             3100..6657
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_4"
                     /sec_met_domain="PFOR_II (E-value: 4.9e-18, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.7e-31, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-11, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-11, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-07, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00025, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-24, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6782..6970
                     /locus_tag="ctg6_5"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(6981..7841)
                     /locus_tag="ctg6_6"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7869..8699)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg6_7"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.8e-28, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8696..9922)
                     /locus_tag="ctg6_8"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10395..11678
                     /locus_tag="ctg6_9"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATDDKSQVQFLSKKNPKMP
                     FFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHGR
                     YFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFLL
                     LILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLCY
                     PHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARPI
                     AAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHTY
                     IIALAGFMLWYWSRPTRTTTDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVWV
                     FFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11641..11973)
                     /locus_tag="ctg6_10"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12001..14766)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 63.7; E-value: 6.3e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_11"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.1e-19, bitscore:
                     63.7, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMRWMKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSW
                     RHKMNDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTP
                     IVEEAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGL
                     SGSTPAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRKHPKIDAVYAHN
                     DRIAPGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQL
                     AMDILEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVAT
                     QQVVLYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQ
                     LSHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVN
                     ILLRLVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDT
                     DYHTLADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMIS
                     AEHIRNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQS
                     CEAVAAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLH
                     TDYTVIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLT
                     ACSLDEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVC
                     DMDKDFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIAR
                     LKKAASLLASSDMTVAEIGYEVGFSSPSYFTKCYKEQFGESPTDFLKRKG"
     CDS             complement(15087..16313)
                     /locus_tag="ctg6_12"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKNWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGLQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 ctcagatttg ctctcgggac ttgataaata ctcacgaata taagacattc gttcatcatc
       61 actgtaatag ttgtactgct ttttcgaata tttcatcttt attttcgatt tttgaagtgt
      121 caacttattc agtacactac aaaactatct gaaactactg ttgatttgat tgacttaacc
      181 gcatgttcca atcacattga acgcatcagc tacttcaata gtactgctct ctctgaaaac
      241 attaaatcat atatcagtca ataatacata aattatcagt ccttaatact tgatttctca
      301 attattaata tctgagaaat caaacgttaa cagttgagat atcagatatt aacatcctgt
      361 aaatcaaaga ataacacagt aaaaacggta tttatcagga cgatgcagag tgagagcaag
      421 tccttgctct cactctgcta ccactggatc tctaacagct aaaacatcga tgaataaagg
      481 gatacagacg aactgttaga gcatgagagc aaaagcacta tctttttcac tgggggagag
      541 taagcaaaag aaacgcacga taccggcttt gaggcgtcac cggtactaac ggcaaatatc
      601 cggcacacac ccgattattc tctacggaca aagggaacga agccgacatc tgccgatgtt
      661 cctccaaagc ctgaccggct aaaggataat aatcaatccg aaaaactcct tccgcatccg
      721 cagccaaata acgatccgtc aagagccatg ccaccacccc catattcatt cgcagattaa
      781 tttcgacaca aggatgaatc cggtaaacag gcgcttcatc cggaaaatga caaatcatca
      841 tatccactcc caagtatcca tgataaaagc caccgaacaa agctgacaat tcttcttcca
      901 aacgagtccg cagcctgata aattcttctt gtggcacata agccgatagt ttctgcagaa
      961 tcttctcgtc agacagcaag tcattccctg catacatccc actcccaccc gtgtggaaga
     1021 ccgaatatcc ggcaaaaaca acccttcctc tcccgtcagc ataaaactcc atagcgaaat
     1081 cttccacctt attatatata ggttcgccta ccaccccacc ctgagaagca gcgacacggg
     1141 cacaccaacc ggaaataaaa gtagtaaata tgcctttaca ccaattcaat cctttcccgc
     1201 ttccggaaag cggagctttt aacaagcacg cttcccgccc ttcgacgaac gcactgcact
     1261 ccgccaaagt actcaaataa aaagattctc cacagaagta ttcattcaac cgcaacccag
     1321 gcaacaactt taccgcctgc agacgatgcg aatgctctct cagaatattc atataatccg
     1381 cagaaggcag ctccgtctga cctgccccca atgtcatcaa acgcttccgc aaagcagggt
     1441 cccaacccca cggagagaac ttccagtctt taccgtcagc cacttccggt tccgtcaaca
     1501 aggccacatc catgcccaaa agttcactct ttgttttcag gaagtccgca ttataagcag
     1561 acggtgcaag caccgcactt cccgcttcgg cataccacat aggaagcaac gccaggtcac
     1621 tcgccatctg tcgggcggaa gccggcgcca tatagttcgt ctcaccgctt gccaacgcca
     1681 tatcatgctc cggattgaat atataaacag gtcttttcgt catgtcaaag atggattcaa
     1741 cacattattc tgcaaatata tacaggaaat aatcaggaac ttacacaata aagagaaact
     1801 tataaattaa agcacatttt tgctatctct actttgcaaa tcctaaaaaa agcactatat
     1861 ttgccagccg aaaaacaaag aaacgaaatg gaatcattct atcgcacaca cgcctacctc
     1921 gttgagcaca ccaatgcccc cgttcgccgc gatcttatgg acgagatcga ctggagtgac
     1981 cgtctgattg gtatcaaagg gacacgtggc gtaggaaaaa ccactttcct cctgcagtac
     2041 gccaaagaga aattcggcac cgaccgttcc tgtctgttca tcaatatgaa caacttttat
     2101 ttctccggtc acagccttgt tgacttcgcc aacgagtttc agaaacgtgg cggaaaagta
     2161 ctgctgatcg accaggtgtt caaacatccc gaatggagca aagagctacg aatgtgctat
     2221 gaccgtttcc ccagcctgaa gattgtcttc accggttctt ccgtcatgcg actcaaagag
     2281 gaaaacctcg aattgcgtga cattgcgaaa agttataacc tgcgcggatt ctctttccgt
     2341 gaatttctga acctgcagac aggaatgaaa ttccgggcat acagcctcga agaaatcctc
     2401 agtacacatg aacagatagc caaaggagta ctttccaaag tacgaccgct ggattatttt
     2461 caggattacc tgcatcatgg tttctaccct ttcttccttg aaaaacgtaa tttctcggag
     2521 aatctgctga aaacaatgaa catgatggta gaagtggata tcttgctgat caaacaaatt
     2581 gagctgaaat atctttcaaa gataaaaaaa ttactatatt tgttggctgt ggacggaccg
     2641 aaagctccga acgtgagcca actggcaagt gacgtacaga catcccgcgc tacggtaatg
     2701 aactatatca agtatctggc agacgcgcgt ctgattaatc tggtttaccc gaaaggagaa
     2761 gaattcccaa agaaaccgtc aaagattatg atgcacaact ctaacctgat gtactccatt
     2821 tatccggtga aagtggaaga acaggatgta ctcgacacgt tcttcgttaa cactttatgg
     2881 aaagaccata aggtacataa aggagataaa aacgtctctt tcatggtaga cgaagtgatg
     2941 ccgttcaaaa tttgtgcgga aggtacaaaa ataaagaata acccggacgt gacgtatgcg
     3001 ttgcaaaagg ctgagatagg ccgcggcaac caaatacctc tttggatgtt cggattctta
     3061 tactaaaaag atttatttac ttaaatattt aatttagtta tgactaaaca gaagaaattc
     3121 atcacatgtg atggtaacca agctgcagca catatctcgt atatgttctc tgaagtagca
     3181 gctatctacc ccatcactcc ttcttcgact atggctgagt acgtagacga atgggctgcc
     3241 gcaggacgta agaacatctt cggcgaaaca gtattggtac aggaaatgca atctgaaggt
     3301 ggtgctgccg gtgcagttca cggttctctt caggctggtg cattgactac tacttacact
     3361 gcttctcagg gtcttctttt gatgatccct aacatgtaca agattgccgg tgaattcttg
     3421 ccttgtgtat tccacgtttc tgctcgtaca ctggcttctc acgcattgtg tatcttcggt
     3481 gaccatcagg acgtaatgtc agctcgtcaa accggcttcg ctatgttggc agaaggttct
     3541 gtacaggaag ttatggattt ggcaggtgtt gctcatctgg ctactatcaa atcacgcgtt
     3601 ccgttcatga acttcttcga tggtttccgt acttctcacg aaatccagaa gatcgaaatg
     3661 ttggaaaacg acgacctcgc tccgctgatc gaccaggaag ctttggctga attccgtgcc
     3721 cgtgcactga atccgatgaa gccggttgcc cgtggtatgg ctgaaaaccc cgaccacttc
     3781 ttccaacatc gtgaatcatg caataactac tatgaagcag ttcctgctat cgtagaagaa
     3841 tacatgaacg aaatttccaa gatcacaggc cgcaaatacg gtttgttcga ttactacggt
     3901 gcagaagatg cagaacgcgt aattatcgca atgggttctg taactgaagc tgcccgcgaa
     3961 gctatcgacc acttggtagc aaacggcgaa aaagtaggta tggttgccgt acacttgtat
     4021 cgtccgttct ctgctaaaca cttcctggct gctgtaccca agactgcaaa gagcatcgca
     4081 gtgcttgacc gtacaaaaga accgggtgct aacggcgaac ctctttacct tgacgttaaa
     4141 gactgcttct atggcgcaga aaatgctcct gttatcgttg gcggtcgcta cggtctgggt
     4201 tcaaaagata ccactccggc acagatcatc tctgtattcg aaaacttggc tatgccaatg
     4261 ccgaagaacc acttcactat cggtatcgta gacgacgtta cgttcacttc tcttcctcag
     4321 aaagaagaaa tcgctctggg cggtgaaggt atgttcgaag ctaaattcta cggtctgggt
     4381 gctgacggta ctgtaggtgc caacaagaac tctgttaaga ttatcggtga caacaccgac
     4441 aaacactgtc aggcttactt ctcttacgac tccaagaagt cgggtggttt cacttgttct
     4501 cacttgcgtt tcggtgatac tccgatccgt tctacttact tggtaaatac tccgaacttc
     4561 gttgcttgtc acgttcaggc ttacctgcac atgtacgacg taacacgtgg tttgcgtaag
     4621 aacggttctt tcttgctgaa taccatctgg gaaggcgaag aactggctaa gaacctgcct
     4681 aacaaggtga agaaatactt tgcacagaac aacatctctg tatactatat caacgcaact
     4741 cagattgcaa tggaaattgg tttgggcaac cgtaccaata caatccttca gtctgcattc
     4801 ttccgtatca caggcgtaat ccctgtagat caagctgttg aacagatgaa gaaattcatc
     4861 gttaagtctt acggcaagaa gggtgaagac gttgttaaca agaactacgc tgctgtagac
     4921 cgcggtggtg aatacaagac tctgactgtc gatcctgctt gggctaacct gccggatgat
     4981 gcaaaagcag aaaacaatga tcctgctttc atcaacgaag tagttcgtcc gatcaatgca
     5041 caggacggtg acttgctgcc ggtatctgca ttcaagggta tcgaagacgg tacttggtat
     5101 caaggtactt ccaaatacga aaaacgtggt gtagctgcat tcgttcccga atggaatgct
     5161 gaaaactgta ttcagtgtaa caagtgtgct tacgtttgtc ctcacgcttc tatccgtccg
     5221 ttcgtactcg atgctgaaga gcagaagggt gctaagttcg agcaactgaa agctgtaggt
     5281 aaagcattcg atggtatgac attccgtatt caggtagacg ttctcgattg tctgggttgc
     5341 ggtaactgtg ccgacatctg tccgggtaat ccgaagaagg gtggcaaggc attgaccatg
     5401 aaacaccttg aaagccagtt ggccgaagct gataactgga cttactgcgc tgaaaacgtg
     5461 aagagcaaac aacacctggt agacatcaag gctaacgtga agaactctca gttcgcaact
     5521 ccgttgtttg agttctcagg cgcttgctcc ggttgtggtg aaactccgta cgtgaaactg
     5581 atttctcagt tgttcggtga ccgtgaaatg gttgctaacg ctacaggatg ttcttctatc
     5641 tactccggtt cagttccttc tactccgtac actatgaacg aaaagggtca cggtcctgca
     5701 tgggctaact ccttgttcga agacttctgt gaatttggtc tgggtatgga actggctaac
     5761 gaaaagatgc gtgcccgtct ggtgaaagta atgaacgaag ctatcgcttc tgattgctgc
     5821 ccggctgaat acaaagaagt atttgctgaa tggatcaaca atatgctgga tgcagaaaag
     5881 actaaggaac tggccgaaaa gatcattccg atggtagaag ctgctaaaga taaatgcaac
     5941 cactgcaagc aaatcgctga tctgcaacaa tatcttgtta aacgcagcca atggatcatc
     6001 ggtggtgacg gtgcttctta tgatatcggt tacggtggtc ttgaccatgt aatcgcttcc
     6061 ggtaaggacg ttaacatcct tgtattggat actgaggttt actctaacac aggtggtcag
     6121 tcttctaaag ctactccggt aggcgctatc gctaagtttg ctgctgcagg taagcgtgta
     6181 cgtaagaaag acctcggtct gatggctact acttacggtt atgtatatgt tgctcagatt
     6241 gctatgggtg ctgaccaggc tcagactctg aaagctatcc gtgaagctga agcatatccg
     6301 ggaccatcac tgatcatcgc ttacgctcca tgtatcaacc acggtctgaa agccggtatg
     6361 ggtaagagcc aggaagaaga agaaaaggct gttaagtgcg gttactggca cttgtggcgt
     6421 tacaaccctg ctttggaaga agaaggcaag aatccgttcc aactggatag caaagaacct
     6481 aactgggaag acttccaagg tttcttgaag ggtgaagttc gttacgcttc tgtaatgaaa
     6541 caatatcctg ctgaagctga agaactgttt aaagctgctg aagaaaacgc taaatggcgt
     6601 tacaacagct acaaacgtct tgccagagaa aactggggag ctgatacagc tgaataataa
     6661 gtagaaatac tttgtacata ataaaaggca ggaatcctgg aaacagattc ctgccttttt
     6721 tgtttatatc ttagaagtaa cgattacttc tcacgaagat attcattaaa actctaaaga
     6781 tatgatcgga tttgttattt ggattatcgg tttgatactg actttcagag ctgccataga
     6841 gatttggaat ataaatgcgg ctgtagagaa aagacttata gcgattgtat taatcgttct
     6901 taccagctgg ctgggactac ttttctacta cttctatggt aaagaaagaa tggcgggatg
     6961 gttgaagtag tgtttgcata tcaatctttc tcaggaatcc aactgttcac cagttcctga
     7021 tgttcttcca tccattgacg ggcagcctgt ctttccgttg tctgcgcctc ttccagagca
     7081 gtcattaagg agctgatttc cgcatctgtc agacgaatgt tgcccaaaag ttcggcagca
     7141 aaagggtctt tctcgctaaa acctttccat gctatggtat gaatggattc cgtatttcca
     7201 tatatcagct tcgggtcctg aagaactttc agcttgaaac ggtcgaacat ccagtgaggc
     7261 gtccatcccg tcacgacaat ccagtctttc ttatcaatcg ctttctttag ggaagcagtc
     7321 atggcaggtc cgctcgaagt catcagttta taatccaatc catagtcttt gatggcctga
     7381 tcggtagctt tcataatacc ggctccggca tcaataccga caatctgacc ggagaaacgt
     7441 tccttttccg cgttcagttc ttcgattgag ttgatcgtaa cgtaatccgg aaccaccagc
     7501 ccgatacggg caccatcata aatatccccg ataacttcga gtttatcccc gtattgtttc
     7561 atataatctt ccatagtgac aggcatccag acatccataa atacgtctgc tttcttacgg
     7621 gagatagagg taaatatagg tgcaaggtcg gcattcagca actttacatc gtacccctga
     7681 tcttcaaaaa tcgctttggc aaggtttgtc attgcaatac cttccgacca gttggcataa
     7741 gcgatactta tcttcttact ctttccgttg tctccgcagg aaacgaaggt taagagtatg
     7801 ccggcaataa acattgccgc aatcattttt atcttattca ttgattattc ctttctttgg
     7861 tgtgattctt atttcttttt actttttctg ttatctgcca taccctgagt gatgcggtcc
     7921 agcacgatcg ccaatatcac gactgcgata ccgccttcaa atccgagtcc gattttcatt
     7981 tgggtgatac ctttcagcac gatttctccc aatcctcccg cagaaatcat ggcggcaatc
     8041 actaccatcg aaagtgacat catgatcgtc tgattgattc ccgtcagaat tgtaggcaat
     8101 gccaaaggca attgcacctt ataaagaagc tgccaaggag tagctccaaa agaacgggag
     8161 gcttctacta cgtttttagg aacctgacga atgcccagac cggtcagacg aaccacagga
     8221 ggcattgcaa agatgatggt ggcaaaagct cccggcacag ttcccaatcc gaagaatagg
     8281 acagcaggaa tcagatagac aaaggcaggc attgtctgca taaagtcgag gacagggcgc
     8341 attatcttgt tacaacgatc actgttggca gtccagattc ccaacggaac gcctaaaagc
     8401 aatgccagac aagtggaaga aagtaccaat gccaatgtct gcatcgtttc ttcccaaaag
     8461 cccatgccgt aaataagcaa taaacccaag agggtaaata cggctgtccc cttacccgac
     8521 ttaaaccagg cgagcgcagc cagcactgca attgtgatat aaaaaggtat tccaaacagt
     8581 acgtgctgaa aaccgtctat gaatcctccg atccccatgc tgagagcatc aaaaaaggaa
     8641 gcaaaatgtt ctgtgagcca attaatggca gtctctatat attgtccgat atttatcata
     8701 attctattgc gttttgaatg atttcattaa tttcttcttt atcttttccc gttacttcga
     8761 tgatcaatga ggaaagtggc actacgcctt caaactcccg attctcattt acgacccaga
     8821 ttggcgagtt cgtttttgtc atcaacggaa gaatatcttc cagcaccgta tcacccagca
     8881 ctgaatgaac ttcatgcctt actacggact cgatggagcg gatttgctct tttcgtagtt
     8941 tcagcaagtc attcaaccgc acctctccta ctaacagatt attggaatcg actaccggaa
     9001 gaacggtcag attccgttcg cgcatcttac ggatcagcac ctccgggcct tctttcttca
     9061 aacgtgccac tatgggttta tctaccataa cagaggaagc tgttataatc ttgcttcgat
     9121 ctacattctc cacaaatcgt tctacataag cgttggcagg ttcggtcagg atttcttccg
     9181 atgtaccgat ttgtacaatt tctccatcct tcatgatagc aatccggtca cccaatttaa
     9241 tcgcttcact caggtcgtga gtaataaaga caatcgtttt tttcatcttc gactgcaaag
     9301 tcagcagttc atcctgcatc tgcacacgga tcaaaggatc gagtgccgag aaggcctcat
     9361 ccatcaacag gacttcggga ttattggcca aagcccgcgc cagcccgaca cgctgctgca
     9421 tcccacccga cagttcactt accatctgat tctcgtagcc tttcagcccc accagttgca
     9481 tgctttccat cgctttctgc tcccgttctc ccttttttac tccctgtagt tcgagcccga
     9541 aagctatatt atgcaagaca gaacggtgag gaagcagacc gaagttctga aagaccatag
     9601 ccagttcttt ccggcgaatc tgcaacagtt ccttatccga cactttggct atgtctgttc
     9661 cattgataat cacttctccg gaagtagggc gtatcaaacg gttgatgcag cggagtaaag
     9721 tggactttcc actaccggac agccccataa tgacgaatat ttcgccttca ttaatggaaa
     9781 gattcgcatc tttcaccgca actgtacatc cggtcgcttt caatatttca ctttttgttt
     9841 taccttcttt caacatcttc aaagccttct gcttctcatt gccaaaaacc agatagagat
     9901 ctttaatttc tattttactc atacaataaa atggtttagg ttattaaaat aatatacaca
     9961 gcaagacaag aacaaacgat aacaggaatc tttctttata tcgtataaag ttctgattta
    10021 aatacgggac aaataacaat gaatcccgaa ataattaata aaatgattat tgacagactg
    10081 agtaattaaa aaaggaatag aatttgataa gataatcctt tcaacgaata gcaaaaaata
    10141 gcatttttat gtataaaaac agcctgttcc agtatcttgc tggcacaaag atacaaaaaa
    10201 cggattaaac atacaaatta tattcaaaat ccggggcata cagagggctt tatttgtaat
    10261 gatatggaaa gtttccgggt aatattcccc tatcactcag caaaatagaa caaaccggca
    10321 gataaatata aaataagttt gaatatttca cttaaacacc gtatatttgg cgtcaataac
    10381 taaactagat ttatatgttc aacagggcta ttacaatttt cctggggaag gataattgtc
    10441 attacacaac aaaagaaaaa caaacaggta ctgccacaga cgacaaaagc caagtacagt
    10501 tccttagtaa aaagaacccc aaaatgccgt ttttctatag ccggcggaat ctctacatga
    10561 taggtttcct gctcgctttt atagtgactc tgctcgaatt tatacgagga cggcatcaaa
    10621 actttatggt cttctcggac gctactcaat tcttctggca aggcatcagc ccatacacaa
    10681 ctgaatttgt agaagctcac ggacgctact tcctttattc tccagttttc acggtattgt
    10741 tcgctccgtt tgcgtatctg cctgcatggc tgggaccttt cgcgtggaat ctattcaatt
    10801 attcgctgtt ctttatggcg atcttcacgc tgccccaaca attcacccag cagcagaaat
    10861 gccgtatgtt cctttttctg ttactgattt taggacaaag tttactttca tttcagtata
    10921 acataacggt agcctattta ttcttattcg cctatacgtt attggaaaaa gaccgtggat
    10981 ttctggctgt tctgttaatc atgatttcgg gatgtaccaa agtatatgga attttcgaac
    11041 tggcattgtt gctgtgctat cctcacgtat ggcgtaactt tggctatgcc gttacaatgg
    11101 gcattgtatt gcttgcatta ccgttaatca aaatagctcc tgcagatttg ctcccctatt
    11161 atgaagaatg gtgccatagt cttgctgttc atcagtccgc cggagcttat gattcatttt
    11221 tctatgcccg ccccattgca gcatggacat taccacactt ccgtgcactt cagataggaa
    11281 tgctcggctt gctgactctg ctctttttgg ggaatttccg caaatggtcg tcttttgcct
    11341 tccgtgccca ggctttgggc attctcatgg gctgggtagt attactgagt gactccgccg
    11401 aaaaacatac ctatattatc gcattggcag gtttcatgct ctggtattgg agcaggccaa
    11461 cacgtaccac aacagacaag attctatttt ggtgctgttt tgtgctgtta tgtatcgttc
    11521 ctatcgacat attcgtccct gtacccatca gagatttcat taccaggacc ttatggcttc
    11581 atgtatgggt tttctttatt gtatggatac ggatgatatg gcttaccttc cttgcatcct
    11641 tcattcatcc acgtgccaca aatgttcttt cagattaacg catccgttag ctttgaaaga
    11701 aacttcttct gccagcaaga gttgtttttg ttccacccaa ccgggcacca gccttccggt
    11761 ggaatttaca actctatggc agggaatgga taattcatcc ggcacttctt tcaatgcacg
    11821 ccccaccatc cgcgagcatt ggggtgcccc caagagcaaa gcaatacctc cataggtaga
    11881 tacttttccc acaggtatct gggatacgac ttcgtacact tccttccgaa aggattcgga
    11941 aaaactctct ttatctactt tataatcttt catatatccc tctttacgat atcaatgaaa
    12001 tcatcctttc cttttcagga agtctgtcgg gctctctccg aactgctctt tatagcactt
    12061 ggtgaaataa gaaggtgaac tgaaaccgac ttcataacca atctccgcta cggtcatgtc
    12121 cgaagaagca agcaaagaag ctgccttctt caaacgggcg atacggagca attcattcgg
    12181 agagtagtta gtcaatgatt taatcttgcg gtaaagctgc acacggctta gtcccatgtc
    12241 tttgcccaag tcctccacat tcaaaccgga gtctcccatt ttctcttcaa tcaatgactt
    12301 gaatctttct acaaaatcct tgtccatatc gcagacatct tcttttgcca atgtctgccc
    12361 gtcaccaaag aactgtttca gacgacggtg agaatcaatc agattgcgga cacgtgccag
    12421 caacagctgt gaactgaacg gctttgaaat ataagaatcc gcaccaccgt catatccctg
    12481 aatacgctgt tcgtccagtg aacacgctgt cagcagaata accggaatat gacaggtctg
    12541 taactcactt ttcagccggc ggcaacattc aatgccatca atgcccggca tcatcacatc
    12601 agaaatgatc aggtccggaa catacttcat agccttacgg attccttcgg agccgtctgc
    12661 cgcttcaatc accgtatagt ctgtatgcaa cagcgtatgg acatacgaac ggatatcctc
    12721 attatcatca ataatcagta cggacggttt ggaagagtca tatccttttt ccagttcttc
    12781 ctcttccgcc aatagaacat ctgttgtacg ggaatccgca gaaacaaggg tggtatccgg
    12841 ttcggcagca acagcctcac aagactgtac aggcagttca acggtaaaga ccgtgccctg
    12901 tttctcatcg ctctctacgg agatcatacc accgtgcatt tctacgaagg cttttaccaa
    12961 tgccagtccg attcccgaac cggtatggtg catatcgatc ttatagaaac ggtcgaatac
    13021 attgcgaata tgttcggcag aaatcataga accggtattt gccaccgtga aacgtatcca
    13081 tcgcttgtcc tctttactaa gggaagacag acggacggct attttcccgt tttccggtgt
    13141 aaacttaaag gcattggaca gaagattgaa ataaatacgt tccagcttct ccatgtctgc
    13201 cagtgtatga taatccgtat ccggcatact atcaaaagaa aaatggatat gcttcttacg
    13261 ggctgccgcc tgaaaagact cattccatcc ttcgaaagaa gaaaggacat ccaccgtaac
    13321 cggagtatat tccatcttgc cgttttcata tttacggaaa tccagaatct gattgaccag
    13381 gcgcaaaagg atattcacat ttcgctgaat cagcatgagc atccggtgct gatctccact
    13441 caatgtcttg tccgccaata aatgttctac cgggtcggca accaatgtca acggagtacg
    13501 gaagtcgtga gaaatattgg tgaagaatac cagcttggca tgagtagctt cttccagttg
    13561 atgagaaagt tgtatcaatt ggtcacgctg ttcttccagt ttgtcacgct gctcttccaa
    13621 ttgctgcttc tgcttaaaaa gctctttatt caagcgattc ttagagcgga gtgatttata
    13681 aacgaccaat aataaaccgg ctaccaataa aaggataatc agactgccgt ataaaacgac
    13741 ctgttgtgta gctacctgag agagatagcc accgatacgt ccgttgagcg tttcaatctt
    13801 tttgtcgagt tcggaaatgt gtgtggtctg caactgcatg acgtgtgcgt tggtacggtc
    13861 cacaacagcg gtattcatca ccgtttcttt gggatagggt ttcttctcca gaatgtccat
    13921 agccagttgc agtaccttat cgccattggt cggatagata aaggtggcat ccagcacact
    13981 gtccagtacc agttccagtc cgtttccctt acccggcaag gcatctatgc cgacaaaaat
    14041 catttccttc tcccgccctg ccatctttgc tgcctgatag gcacccggag cgatacggtc
    14101 attatgggca tacacagcat caatcttagg atgcttccga agcatactat ccatttctat
    14161 ctctgccgga ccacgttccc acgcagcatc cgctttatca atcagcttta tatccgggaa
    14221 tttactgatg gcagccataa atccctgatg ccgttccatt gcaggagtcg aaccgctcaa
    14281 tcctgtcagt tctactatat ttcccttccc ttttagactg gaggcaatat agtttcctac
    14341 cgaacgaccg atttcataat tatcggctcc gatataggca gtatatttat ccgaaagaat
    14401 cttccggtct acaagaataa cggggatgcc tttctgataa gcttcttcta caatcggagt
    14461 cataggagca gcttcgttag cggaaataat cagcagatcg actccttcgt ccataaaata
    14521 atggacatct tccgcctgct tactgttatc atcccctgcc gaacggattt ccaccgaaac
    14581 accattataa aacatcgctt cccgaagaat ctcatcattc atcttatgtc gccatgaatc
    14641 atcgctgcat tgagccaccc caatacgaaa acggggtgta tcctgccggc aagccgtcat
    14701 cccgattaaa ccaaacagca ccagcatcca cttcagatat ctcatcgtct tcatccatct
    14761 catcatttca tagttctttc tgtaatccaa ttaagaacaa aaataagaaa taatactgta
    14821 aagttctcta acttcagcta tttattattc taaaaagaag gaaagcagtc ctctttcaga
    14881 ccatcggaaa gtatcaacaa aagtataaag cgtaaaacaa acacttaatc aatgttataa
    14941 aacatagcgt tttacttgga taatttgcag atttcacaga agtccgtatc tttgcactgt
    15001 gtttttcata gtattagatt taaggttaac aaaggttgga gcaaggcgtt gctccttttt
    15061 ttatgccctg acctttcatc taccggttag ttttcatccc attccttttc cagtttacca
    15121 tcaatagtgt agcgtttcca tcgtcctaca cggcgaccat tcttatattc cccacattca
    15181 cgaagctggt cattctttac ataacgagct tcgaacggtc cgttctgcct tccgttcaca
    15241 taggtagaag tttcccaata atcaaagcgg ttgctcacta tcagccgtcg ttccttgcca
    15301 tgcaatctgc cggcctgata ggtagcttca tatctcaatt caccattttc cagattatat
    15361 tcacggtata aaccgtcttt acgatcgttc ttcatataat attctttctg ccttacccca
    15421 cttccgttgg caaatgagac atggagtcca tcttcttttc catccagata ggtttcaatc
    15481 atcagcgtat ctccgctttc agcaaaagta gtccaccgac cattcttctt tccattctta
    15541 taactaccca gtatacgtgg cgagccaaac gtaaacacgg acgaatattc accgtcctgc
    15601 aaaccttctt cattgaaata aacggtctca tacaaatcat atgtaccttt cagaaaagta
    15661 tactgtttgc ctacctgctt cccgtccttg taattatgct ctttccgcaa agtaccgtca
    15721 gattcgtacg acagttgctt cccgtgctct ttccccatcc ggaagtttct ttcactttcc
    15781 acttttccgg tagtaaagta acttttgctc gtaccatcca gcttaccttc cttataggac
    15841 ttttcttctt tcagcttacc gtcaaacttg gagttaatct tgaagaggcc atccttccgc
    15901 ccttctttat aacttccttc cgttattaat atattgtcca catattcttt gtatccgcca
    15961 tcataaaaac catctttaaa agatgccagc acataggcgg aatgataacc atctatgatg
    16021 cgatgttcgc cattcaatgc tttttccgtt ttcagttcct gaaacaacag tctgccatca
    16081 cctacattaa caacagatac ctgatcgatc ttatattcct tttgcgcaaa caaaggaaga
    16141 gcaagatata aaaacaaaaa tacgttccag ttttttgatc tgaggaagtt cgaaatgtgt
    16201 ttcataaagt agttttctct ttttgattta ttatttaaaa acctgccgca aagataggca
    16261 atcggcttat aaaacaaggc aaggaagagg gggacaatta gaaaaaagaa catctgttat
    16321 tatcattcta ataattaaca gattaagtag taaatcaaaa cgcagggaag ggggacattt
    16381 actgaaataa gaaacagaaa agaaggtgtg tcaaaagcaa ctaaattccc ctccttcggg
    16441 aaggagggga atttagttgc ttttgacaca ccttcttttt gaatttaaag agattctaca
    16501 acaatctgtc tttcagaaca accggaagtt cgggcattgc accgctctgc gtacaaacat
    16561 aagcggaaac ttcgacagcc agcttatgag cttcgggaac agacttgcca ttcagaatgg
    16621 aagcacagaa agcggcagta aaggaatccc ccgctcc
//
