Select genomic region:
Overview
1.1
2.1
2.2
4.1
6.1
10.1
18.1
44.1
59.1

### Identified primary metabolite regions

c00001_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_1)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | TPP_AA_metabolism | Putative | 1,368 | 27,347 |

c00002_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_2)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 2.1 | GR_fatty_acids,Pyruvate2acetate-formate | SCFA | 60,119 | 84,793 | Pyruvate to acetate-formate B. thetaiotaomicron | PFL_acetate | 100%
Region 2.2 | TPP_fatty_acids | Putative | 106,558 | 131,414 |

c00004_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_4)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 4.1 | Rnf_complex | E-MGC | 44,810 | 69,959 | Rnf complex C. sporogenes | RNF | 83%

c00006_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_6)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 6.1 | PFOR_II_pathway | SCFA | 1 | 16,657 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%

c00010_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_10)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 10.1 | Fumarate2succinate | SCFA | 1 | 21,877 | Fumarate to succinate B. thetaiotaomicron | SUC | 100%

c00018_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_18)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 18.1 | succinate2propionate | SCFA | 43,192 | 78,461 | Succinate to propionate B. theta | PRO | 100%

c00044_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_44)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 44.1 | NADH_dehydrogenase_I | E-MGC | 116,940 | 147,131 | NADH dehydrogenase I Bacteroides sp. | NADHD | 66%

c00059_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_59)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 59.1 | porA | SCFA | 20,144 | 42,992 | porA C. sporogenes | POR | 60%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | TPP_AA_metabolism | Putative | 1,368 | 27,347 |
Region 2.1 | GR_fatty_acids,Pyruvate2acetate-formate | SCFA | 60,119 | 84,793 | Pyruvate to acetate-formate B. thetaiotaomicron | PFL_acetate | 100%
Region 2.2 | TPP_fatty_acids | Putative | 106,558 | 131,414 |
Region 4.1 | Rnf_complex | E-MGC | 44,810 | 69,959 | Rnf complex C. sporogenes | RNF | 83%
Region 6.1 | PFOR_II_pathway | SCFA | 1 | 16,657 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%
Region 10.1 | Fumarate2succinate | SCFA | 1 | 21,877 | Fumarate to succinate B. thetaiotaomicron | SUC | 100%
Region 18.1 | succinate2propionate | SCFA | 43,192 | 78,461 | Succinate to propionate B. theta | PRO | 100%
Region 44.1 | NADH_dehydrogenase_I | E-MGC | 116,940 | 147,131 | NADH dehydrogenase I Bacteroides sp. | NADHD | 66%
Region 59.1 | porA | SCFA | 20,144 | 42,992 | porA C. sporogenes | POR | 60%

No primary metabolite regions were found in these records:
  c00003_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_3)
  c00005_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_5)
  c00007_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_7)
  c00008_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_8)
  c00009_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_9)
  c00011_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_11)
  c00012_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_12)
  c00013_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_13)
  c00014_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_14)
  c00015_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_15)
  c00016_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_16)
  c00017_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_17)
  c00019_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_19)
  c00020_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_20)
  c00021_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_21)
  c00022_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_22)
  c00023_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_23)
  c00024_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_25)
  c00026_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_30)
  c00031_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_31)
  c00032_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_32)
  c00033_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_33)
  c00034_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_34)
  c00035_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_38)
  c00039_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_39)
  c00040_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_40)
  c00041_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_41)
  c00042_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_43)
  c00045_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_45)
  c00046_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_46)
  c00047_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_47)
  c00048_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_48)
  c00049_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_49)
  c00050_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_50)
  c00051_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_51)
  c00052_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_52)
  c00053_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_53)
  c00054_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_54)
  c00055_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_55)
  c00056_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_56)
  c00057_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_57)
  c00058_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_58)
  c00060_gnlPro.. (original name was: gnl|Prokka|DIFIJOHI_60)

Compact view
c00001_gnlPro.. - Region 1 - TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1,368 - 27,347 nt. (total: 25,980 nt) Show pHMM detection rules used
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00002_gnlPro.. - Region 1 - GR_fatty_acids,Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 60,119 - 84,793 nt. (total: 24,675 nt) Show pHMM detection rules used
GR_fatty_acids: (minimum(1, [Gly_430_pcre, Gly_8-9_TMA, Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline, PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1, ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C, Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and not (POR or POR_N or PFOR_II))
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00002_gnlPro.. - Region 2 - TPP_fatty_acids
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 106,558 - 131,414 nt. (total: 24,857 nt) Show pHMM detection rules used
TPP_fatty_acids: (TPP_enzyme_C and (minimum(2, [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1, ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C, Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and not (POR or POR_N))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00004_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 44,810 - 69,959 nt. (total: 25,150 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00006_gnlPro.. - Region 1 - PFOR_II_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 16,657 nt. (total: 16,657 nt) Show pHMM detection rules used
Region on contig edge.
PFOR_II_pathway: cds(POR and POR_N and PFOR_II and EKR and Fer4_16 and TPP_enzyme_C)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00010_gnlPro.. - Region 1 - Fumarate2succinate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 21,877 nt. (total: 21,877 nt) Show pHMM detection rules used
Region on contig edge.
Fumarate2succinate: (Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or Fer4_7 or SucD_FumR))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00018_gnlPro.. - Region 1 - succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 43,192 - 78,461 nt. (total: 35,270 nt) Show pHMM detection rules used
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00044_gnlPro.. - Region 1 - NADH_dehydrogenase_I
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 116,940 - 147,131 nt. (total: 30,192 nt) Show pHMM detection rules used
NADH_dehydrogenase_I: (Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00059_gnlPro.. - Region 1 - porA
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 20,144 - 42,992 nt. (total: 22,849 nt) Show pHMM detection rules used
porA: (Fer4_7 and TPP_enzyme_C and POR and POR_N and PFOR_II and not (EKR or Fer4_16))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.