LOCUS       c00200_gnlPro..        17617 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FCJJBCGJ_200.
ACCESSION   c00200_gnlPro..
VERSION     c00200_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 15:26:32
            Original ID  :: gnl|Prokka|FCJJBCGJ_200
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 15346
            Orig. end    :: 32963
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17617
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[25346:28317]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12971
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17617
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17617
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             1550..2626
                     /locus_tag="ctg200_15"
                     /transl_table=11
                     /translation="MDYMKDNKEISAEEAVILWQASRLSLSKSYEKAPEILKVHGSVIG
                     TLGNFSASIGKAKSKKTFNVSAIVAAALKNGTVLRYVAELPEDKRKILYVDTEQSPYHC
                     LKVMKRILRMAGLPDDRDNENLEFLALRKYTPEQRIRIAEQAIYNTPNIALVIIDGIRD
                     MVYDINSPGESTRIISKLMQWTDDRQIHIHTILHQNKGDENARGHIGTELNNKAETVLL
                     VEKDKNNGDISKVSAMHIRAMDFEPFAFRINDNALPELMEGYKPEAKKPGRPEEEKFDP
                     YRHITEQQHRIALEAVFGLKEEYGYKELENALIKSYTSIGVKLNHQKAVPLITMLRNKR
                     MIVQENGRKYTFMPDFHY"
     CDS             complement(3196..3744)
                     /locus_tag="ctg200_16"
                     /transl_table=11
                     /translation="LPFSFNLFLQVFIQVLASVVSLRSVTDVQVSAVFLADLSESFHAC
                     MVVVKKAVDAFVAAQRIESLVYIRYGVQYNVVLSVQLRIIRAALLSQCQKGEVVHESLE
                     HITGIPCFPRLPDVGDFLGCDATLEIAVANLKSTRTIGKGDGKVPFAIVGETGFTTFSF
                     CQFHIYSSSLQVGKQGRGR"
     CDS             4025..5428
                     /locus_tag="ctg200_17"
                     /transl_table=11
                     /translation="MATKSSIHIKPCNIASSEAHNRRAAEYMRNIGESRIYVVPELSTD
                     NEQWINPDFGTPELRTHYDNVKRMVKEKTGRAMQEKERERKGKNGKTIKVAGCSPIREG
                     VLLVRPDTTLADVRKFGEECQRRWGITPLQIFLHKDEGHWLSGHPEAEDRESFQIGERW
                     FKPNYHAHIVFDWMNHETGKSRKLNDEDMTEMQSLASDILIMERGQSKAVTGKEHLERN
                     DFIIEKQKAELQRIEETKRHKEQQISFAEQELKQVKSEIRTDKLKSVATDAATAIASGV
                     GSLFGSGKLKDLEQSNENLRHEIAKRDKGIDELKAKMQQMQEQHGKQIRNLQGIHNQEL
                     ETKDKEISRLNTILEKAFNWFPLLKEMLRMEKLCYAIGFTKDMVNSLLTKKESIRCNGK
                     IYSEEHRRRFEIKNDVFKVEKSPVDDNKLVLTINRQPIGEWFKEQWKKLRQGLRQSAEE
                     PRKSRGFRM"
     CDS             complement(5688..5855)
                     /locus_tag="ctg200_18"
                     /transl_table=11
                     /translation="MYAYLYISIGAFLTITGVRSGAHPFANRMVQKTNSQFLIAFIHYT
                     FILQLPQRMG"
     CDS             5872..6228
                     /locus_tag="ctg200_19"
                     /transl_table=11
                     /translation="LTSSTGGTYGGQYGIYGSSTTKSVNPSDVIAGILIKQGYIILPEL
                     KSELANETLIVNYGESGRRNRGLGYTIEVTIQFSSAKTNEMICSCTAEGQGETEADDIR
                     QAIRRALSSLFPEK"
     CDS             6260..6919
                     /locus_tag="ctg200_20"
                     /transl_table=11
                     /translation="MKKLIVSFALMVITLASYAQVYKMYSTRNYHNQLRLNTMTGEVQQ
                     IQDDGQSWIICSAREISGDKESRFCLYETQNMWTFIMLDTYTGKNWQVQFSVKGEDYMF
                     AAPINIFSLAYPEATSNWTNRFQMFATQNMWTFILLDSYNGRLWQVQYSTQDLDNLFCI
                     PINKDELGSDNEKCIFSIQPLTSMYQYYLINDRTGDMWKFQWSTKGDDYRWIEKFK"
     CDS             6935..9553
                     /locus_tag="ctg200_21"
                     /transl_table=11
                     /translation="MQLVLLIVVVSLVAISVIAVATIRIRLKNKSKELSEKLNHISSYS
                     NKSNYEQAKERLSALNNEAFIDIPTDLNNVFSCKIISATQEKDFTNHYIPYFQEAHSLV
                     KRLEAFNITPSVAISNLIRDFGNINKIVEQHNDAVINSLLDTHKEFFDHCLKYPLDKQQ
                     RRSIVSEEDNCLVVSSAGSGKTSSIVGKVKYLTEIKGIVPHRILLISYTNKAAAELTER
                     MATNGLKGYTFHKLAIDIIGRATGTKPSICDNTDSLFVDIYHTLLGNKDFKNSIVEYFI
                     DYQSNEADWEQRKNERREKLSEQKNVQLKAMCPDMDGRAIYVRSEQEQKICFVLSSLGV
                     RFRYEEAYEHQLADEMHSQYRPDFSIYFEQNGVTKRIYLEHFGVDEHGLVPAWFAKDKN
                     ITYEEANQKYNDGITWKKAAHEKFGTQLLVTSSADFHYSDIRDKLRKLLDDAGVPIQEK
                     TDEELYDLVLPKGSKQEKAFIRLVVTFVTLVKSSCKSVKDVLKRAKYAEDERSVFIIKN
                     IFQPVYERYISALRDNNQIDFTDAILQATEICRVSRPVEYDYIIVDEFQDISVDRYNFL
                     KVLREGNPPAKLYCVGDDWQSIYRFSGSDMALFNQFSEYFGATEINKIETTYRFGEPLV
                     SLSSHFIQRNKSQIQKDIHSFSSEMKTELEFYSYDRRDYCNTIGQLVASIPSDKSIFLL
                     GRYSFDDYYLSFMYQSIKEGNRFFYVIGGRKIEFLTVHKSKGLEADYVILLQCNKDTYG
                     FPSLVSDDPVLNYVLTKSDQFPYGEERRLFYVAITRAKMKTLVLYDKRFPSVFVDEFLH
                     PEKVSEESYVKHPNANKRWTRGADQFLLKLYSEGKSVRYIATKMGRSQTSIVMRLNKLN
                     Q"
     CDS             10001..12229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg200_22"
                     /sec_met_domain="Gly_radical (E-value: 1.9e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             12246..12971
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.5;
                     E-value: 1.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg200_23"
                     /sec_met_domain="Radical_SAM (E-value: 5.6e-29, bitscore:
                     92.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKGG
                     TPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSNG
                     GLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRYV
                     LVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTPE
                     QLEKAAEVFKEYFTTVVVN"
     CDS             complement(12964..13413)
                     /locus_tag="ctg200_24"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(13400..13567)
                     /locus_tag="ctg200_25"
                     /transl_table=11
                     /translation="MKEIVSRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(13627..14124)
                     /locus_tag="ctg200_26"
                     /transl_table=11
                     /translation="MTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITSRS
                     TCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIKGA
                     HLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAPDP
                     TV"
     CDS             14324..14554
                     /locus_tag="ctg200_27"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             14641..16755
                     /locus_tag="ctg200_28"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     DYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIVGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETASLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYACTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(16825..17130)
                     /locus_tag="ctg200_29"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(17111..17443)
                     /locus_tag="ctg200_30"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLMLLQTQDRIPLKFM
                     RLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIDKAKILRKEY
                     YGSKNK"
     CDS             17460..17615
                     /locus_tag="ctg200_31"
                     /transl_table=11
                     /translation="MLFNYTTYFLVLYYFSSSSPPKVRGVREELKLFLFYFFISTFYIS
                     LKKIRML"
ORIGIN
        1 cggagaactc aacaggatat ataatgattg ggtgaccaat tatgcttttt cttttgacaa
       61 gcaaaaattc atcaccgatt tttacaggca gcacaatgat acaaaggctt ttgaatccgc
      121 tatccttgaa ctggtacttg acaagcataa agaacaatac acattgattc tcaatagttt
      181 aaaaatcgaa atagaaaaga atatacgggc ttatgaaaca aaaccgctga atgatgacat
      241 cataaagcgt gtgtgttttc actacgcaga cagacgtaat tctgcaatta gagaccagtt
      301 ggagattacc accaagttgc acgagccttt gaatgacgca taccacagat atgatttcat
      361 tggttttcgg gagcatacgg acgaagaaga aatacaggca gaaaaggaat atgaacgctg
      421 caaggctgaa tacgacaagg aaaagaagga attggataaa ctctatgaac tgcaaaagca
      481 agaccagaaa gaggcttttc aatatatcga aaacctttcc agtgatgttt accgcctaag
      541 ccttcttttc atggaagtcc tgaaaaaata ccttcctgat gatgtggaag aaaaacgacc
      601 ggaggaatca gtcgagcaaa atgcgcaaga agaagtacag aatacaccgg aggaacagca
      661 tgaatatttt gacatgaagc cgctttcgcc tatttatgaa acctgtgtcg gggaacagtt
      721 cgaagccatt accatagcgg acttctatgc caatataaat ctgtacccct gcaagaacag
      781 attaaaaatc aaggcaaggg aaaagatacg ggtgtgttac ctgatattcc tgatgagtga
      841 aaaactatcc aagcaataca gggacgaatg gcgagacaag atattgaaac tactggatat
      901 tgacgagagc tattacagat cgaagtacaa agaacccgtt tccgattttc caagtgatag
      961 caaccagaaa ttcgccaaag aaatggaaag catattcaga taattcgtga tacatcctga
     1021 cattccatga aattaccact tttaccactc aaattaattt ttgagtggta tttttattct
     1081 ctgatattca gatgaataat aagacattcc atttacatta accacatcct taccacttat
     1141 aaccctacct aattttgcat cgttcgagaa catagataac agccagtgcg cagggctgat
     1201 tgtttaacga ctaaatagat tggacgatga caaatcttca agagttatta ttaaaacccg
     1261 tctggcagat gacaggcgaa gagttcatat tcctaagcaa gcacgcttcc aaccaaacgg
     1321 aagcgcaacc gcagcccatc acggacatgg aaaggaagta tgtgtacgga ataccgggca
     1381 ttgccaaact gttcgggtgc agcctgccca ccgccaaccg tataaagaaa agcggaaaga
     1441 ttgacaaagc cattacgcaa atagggcgca agattatcgt tgatgcggaa cttgcccttg
     1501 aactggccgg aaagaaaacc ggaggacgaa aataacggga ggtgtactta tggattatat
     1561 gaaagacaac aaggaaatat cggcagaaga agccgtaatc ctttggcaag cctcacgttt
     1621 gagcctgtcg aaaagttatg aaaaagcacc ggagattctc aaagtacatg gttccgtcat
     1681 agggacattg gggaatttca gtgcatccat cggcaaagcc aagagcaaaa agacgttcaa
     1741 tgtgtcggct atcgtagccg ccgcattgaa gaacggcaca gtgctgcgat atgtggctga
     1801 acttccggaa gacaaacgga aaatccttta tgtggacacg gaacaaagcc cttatcattg
     1861 cctgaaagtc atgaaacgta ttttgcggat ggccgggctt cccgatgaca gggacaatga
     1921 aaatcttgaa tttcttgctt tgaggaaata cacgcccgaa cagcgtatca ggattgcaga
     1981 gcaggctatc tacaataccc ccaacatagc ccttgtaatc atagacggta ttcgtgatat
     2041 ggtatatgac atcaacagcc ccggcgaatc cacacgcatc atatccaaac tgatgcagtg
     2101 gacggacgac aggcagatac atatccatac gatactgcat cagaacaaag gggatgaaaa
     2161 tgcgagaggg catatcggta ctgaactgaa caacaaggca gaaaccgtac tccttgtgga
     2221 aaaggacaag aacaacgggg atataagtaa agtatcagcc atgcacataa gggcaatgga
     2281 cttcgagcct ttcgcattcc gtatcaacga caatgccctg cccgaactca tggagggtta
     2341 caagcccgaa gccaagaaac cgggaaggcc ggaagaggaa aagtttgacc cttacaggca
     2401 catcaccgaa caacagcacc gcatcgcact ggaagcggtt ttcggactga aagaggaata
     2461 tggctacaag gagctggaaa atgccttaat caaaagctat acgtcaatag gtgtaaagct
     2521 gaaccatcaa aaggcggtac cgctcatcac catgcttcgc aacaaacgga tgatagtgca
     2581 ggagaacggc aggaaataca cgttcatgcc cgacttccac tattagcctg ttgtttgtaa
     2641 tcgcttcact ttattctgtg ggtctatata ttaggaataa agcgaagcgg ttgcaggaag
     2701 tacaaaacca cttcacttta ctaccgtatc ctatatatac gaaaataaag tgaagtggtt
     2761 atacagaccg tacttcttaa aatggtacgg gcgaaaagaa aaacgaatca atttagcaac
     2821 caatttacca actactaaaa caatcatttt atggatatac agacagccaa gcaaatcagg
     2881 atagcagatt ttctgcacag tttgggatat tctcccgtca agcaacaagg tatcaacctg
     2941 tggtataaat caccgttaag ggaagaagca gaagcttcgt tcaagataaa taccgaacgt
     3001 aaccaatggt atgacttcgg tttgggcaaa ggtggcggta tcattgaact ggctgcacac
     3061 ctgtatgcta ccgaccatgt accttacatt ttaaaacgga tagcggaaca gacaccgcat
     3121 gtgcgcccgg tatctttctc ttttggcaag caaaactctt ccgaaccgag tttccaacag
     3181 ttggagattg ttccgttatc gtcccctgcc ctgcttgcct acttgcaggg aagaggaata
     3241 aatatggaac tggcaaaaag agaatgtagt gaagcccgtt tcacccacaa tggcaaacgg
     3301 tactttgcca tcgcctttcc caatggttcg ggtggatttg aggttcgcaa ccgctatttc
     3361 aagggttgca tcgcacccaa ggaaatctcc cacatcaggc agtcggggaa agcaaggaat
     3421 acctgttatg tgttcgaggg attcatggac tacctctcct ttctgacatt gagacaggag
     3481 agctgcccga attatccgga gttggacgga caggactaca ttgtattgaa ctccgtatcg
     3541 aatgtaaaca aggctctcta tccgttgggc agctacgaac gcatccactg cttttttgac
     3601 aacgaccatg caggcatgga agctctccga caaatccgca aggaatacgg cagagacctg
     3661 tacatccgtg acgcttcgca gacttacaac ggatgcaagg acttgaatga atacttgcag
     3721 aaacaggttg aaagaaaaag gcaagtccgg tctgtcaaag agacgcgcag ccagtcaccg
     3781 aaaaagaaga acggctttca gttatagccc actataacta cacgctccgc tttcgtagtt
     3841 gtgggctctc ccgaggggat tagggctttg ccctaatgac ccactcaggg cgtttcaccc
     3901 ctgagaaccc cgagcaaaga gtgaccctct ctttgcaatc tccgcttatg ggttacaccc
     3961 cctaagaacc cctctgcgga agcgagcaaa gcaatcaatt gtaaacaata aaaacagaat
     4021 agttatggca acaaaatcaa gcatacatat caagccttgc aacatcgcat cgagcgaggc
     4081 gcacaaccga agggctgccg agtatatgcg taatatcggg gagtccagaa tctatgtcgt
     4141 tcccgaactt tccaccgata acgaacagtg gataaatccc gacttcggca ctcccgaact
     4201 gcggacgcac tatgacaacg tcaaacgaat ggtcaaggaa aagaccggac gtgccatgca
     4261 ggaaaaagaa agggaacgca agggaaagaa tggaaagact atcaaggtgg cgggatgttc
     4321 ccccatccgt gagggagtgt tactcgtcag accggacacc acactggctg acgtgcgtaa
     4381 attcggcgag gagtgccaaa ggcgttgggg catcacaccg cttcaaatct tcctgcacaa
     4441 ggacgagggg cattggctga gcggacaccc cgaagccgaa gatagggaga gtttccaaat
     4501 aggcgaaaga tggttcaaac cgaattatca tgcccatatc gttttcgact ggatgaacca
     4561 cgaaaccgga aaaagccgaa aacttaatga tgaagatatg accgaaatgc agagcttggc
     4621 atccgacatt ctaataatgg aacgtgggca gtcaaaggcc gtcactggca aagagcattt
     4681 agagcgaaac gactttatca ttgaaaaaca gaaagctgaa ctgcaacgta tagaggaaac
     4741 caaacgacac aaggagcaac aaataagctt tgccgaacag gagctgaaac aggtaaaatc
     4801 ggagatacgc accgacaagc tcaaaagtgt agccactgat gcagccaccg ccatagcaag
     4861 tggtgtcggt tctcttttcg gcagcggtaa attgaaagat ttggaacaat ctaacgagaa
     4921 tttacgtcat gaaatagcca aacgtgacaa gggtattgat gaattaaaag ccaagatgca
     4981 acaaatgcag gaacagcacg gcaagcagat tcgtaacctg caaggaatac ataatcaaga
     5041 gcttgaaacc aaagacaagg aaatatcacg attgaacacc attcttgaaa aagcattcaa
     5101 ctggttccca ttgctcaaag agatgttgag aatggaaaaa ctatgttatg ctatcggatt
     5161 taccaaagac atggtaaaca gtcttttgac caaaaaagaa tctatcaggt gtaatggtaa
     5221 aatttattcc gaagagcata gacgaagatt tgaaatcaag aatgatgttt tcaaagtgga
     5281 gaaaagtccg gtcgatgata acaaattggt gctgaccata aaccgacaac cgataggtga
     5341 atggttcaag gaacaatgga agaaattaag gcaaggtttg cgacagtctg cggaagagcc
     5401 aagaaaaagt agagggttca gaatgtaatt ttgatagtat ttgattgtat ctcaataaaa
     5461 ttaaatatct ttgtaagcgg attgaggcaa ctctttccaa gacataagaa aaaagaagaa
     5521 gcgttatgct tatcttgtac ttgaaaacgt aggaaatttt caaattggat acaaggatag
     5581 catagtggtt ctcacgctat agcgtgggct gctattgtta catccgtatc caaggtttcc
     5641 tacgaccttc aagtaagagt gtggcataca gttccacgct tcgtgattta acccatcctt
     5701 tgtggaagct ggaggataaa tgtgtagtgt atgaacgcaa ttaaaaattg gctattagtt
     5761 ttttgcacca ttctattagc aaatgggtgt gcaccacttc gaacacctgt aatagtaagg
     5821 aatgctccta ttgaaatgta taaatacgca tacatttctc cgacaaagga attgacatca
     5881 agcacaggag gtacatatgg aggtcaatat ggtatctatg gctcttcaac taccaaaagt
     5941 gttaatccga gtgatgtgat agcaggaata ttgataaaac aggggtatat tatattgcct
     6001 gaactcaaat ccgaattagc gaatgaaacc ttaattgtca attatggcga gagtggtagg
     6061 cgtaacagag gtttaggcta tacaatagaa gtaaccatac aatttagttc tgcaaaaacc
     6121 aatgaaatga tatgctcttg tacggcagag gggcaaggag aaacagaagc tgatgatatt
     6181 cgccaagcca ttagacgagc attgtcaagt ttattccctg aaaaataaaa tcaattaata
     6241 gccaataata taataaatta tgaagaagct tattgtatca tttgcattga tggttattac
     6301 gttggcatcg tatgcccaag tttataaaat gtatagtacg cgaaactatc ataaccagct
     6361 tcgtttaaat acgatgacag gtgaagtgca gcaaatacaa gatgatggtc agtcttggat
     6421 tatttgtagt gcaagagaaa tatctggaga taaggaaagt aggttttgcc tttatgaaac
     6481 acaaaacatg tggactttca taatgcttga tacatataca gggaaaaatt ggcaagttca
     6541 atttagtgta aaaggtgaag attatatgtt tgctgcccca atcaacatct tctctcttgc
     6601 atatcccgaa gcaacttcaa attggactaa taggtttcag atgtttgcca cccaaaacat
     6661 gtggactttc atattattag attcgtataa tggacgacta tggcaagtcc aatatagcac
     6721 acaagattta gataatctat tttgcatacc tataaacaaa gacgaattag gatccgataa
     6781 cgaaaaatgt atattctcta ttcaaccatt gacaagcatg tatcaatact atcttataaa
     6841 tgataggaca ggtgacatgt ggaaattcca atggagtacc aagggggatg attataggtg
     6901 gattgaaaaa tttaaatagt catcatcctc tgatatgcag ttggttttac ttatagttgt
     6961 ggtttctctt gttgctattt ctgttattgc agtagccaca atacgaatac gcctaaaaaa
     7021 caagtccaag gaactttcag aaaagttaaa ccacatatct tcttatagca ataaatccaa
     7081 ttatgagcaa gcaaaagaga gattgtcggc attaaacaac gaagcattta ttgatattcc
     7141 gaccgacctt aataatgttt tttcatgtaa gataatctct gcaacgcaag aaaaggattt
     7201 cacaaatcat tatataccat attttcaaga ggcgcattca ttagtcaaga gacttgaagc
     7261 cttcaatatc actccatctg tagcaatctc aaacctaatt cgtgactttg ggaatatcaa
     7321 taagattgtc gagcaacata atgatgcggt tataaattct ttacttgata cacataaaga
     7381 atttttcgac cattgtttga aatatccatt ggacaagcag caaagacgct caatcgtttc
     7441 agaagaagat aattgcttgg ttgttagtag cgcaggtagt ggaaagacct cttctattgt
     7501 tggaaaagtc aagtatctaa cagaaataaa aggcattgta cctcatagaa tcttactcat
     7561 tagttacacg aacaaagcag cagccgaact tacggaaaga atggctacta acggcttgaa
     7621 aggttatact tttcataaat tagccattga tattattgga agagcaacag gcacaaaacc
     7681 atctatttgc gataatactg attctttatt cgtagatatt tatcacactt tattagggaa
     7741 taaggatttt aagaatagta tagtagaata ttttattgat tatcaatcca atgaagcgga
     7801 ttgggagcaa cgcaagaatg aaaggcgaga aaagttatcg gaacaaaaaa atgttcagtt
     7861 aaaagcaatg tgtcccgata tggatggtcg agccatatat gtgagaagtg agcaagagca
     7921 aaagatatgc tttgtcttgt cttcacttgg agtaagattc agatatgaag aggcatacga
     7981 acatcaattg gcagatgaaa tgcactctca atatcgcccc gatttttcca tatatttcga
     8041 gcaaaatgga gtaaccaaac gaatctatct ggagcatttc ggggttgatg aacatggtct
     8101 tgttccagct tggtttgcaa aggataaaaa tataacatac gaagaagcca atcaaaaata
     8161 taatgatggt ataacttgga agaaagcagc tcatgagaaa tttggcactc aacttttagt
     8221 aacatcaagt gctgatttcc attattctga tattagggat aaactccgta aactattaga
     8281 tgatgcaggt gtaccaattc aagagaaaac ggatgaagag ttatatgatt tagttttacc
     8341 caaaggaagt aagcaggaaa aggcatttat acgacttgtt gttacttttg tgacattagt
     8401 gaaatcaagc tgtaaatcag ttaaggacgt tcttaaacga gcgaagtatg cagaggatga
     8461 acggagtgtt tttattatca agaatatatt ccagcctgta tatgaacgct atataagcgc
     8521 attaagagat aataaccaaa ttgattttac tgatgcgatt cttcaagcca cagaaatatg
     8581 tcgtgtttca cgtcctgttg agtatgatta tatcatcgtg gacgagtttc aagacatatc
     8641 tgttgaccgt tataactttt taaaagtgtt gcgtgaggga aatccaccag caaagttgta
     8701 ttgcgtaggc gatgactggc agtccatata tcgtttttcg ggaagtgata tggctctttt
     8761 caatcaattc tccgaatact ttggagcaac agaaataaat aagattgaaa ccacatacag
     8821 atttggagaa cctttggttt cgttgtcctc tcatttcata caacgcaata aatcacaaat
     8881 tcagaaagat atacactcgt tcagttctga aatgaaaaca gaattggagt tttattctta
     8941 tgacagacgt gattattgca atacgatagg gcaacttgta gcttctattc catcagacaa
     9001 atcaatattt ttgttgggac gttattcctt tgatgattat tatctctctt ttatgtacca
     9061 atccatcaaa gagggcaata ggttctttta tgtgatagga ggacgaaaaa tcgagttttt
     9121 gactgtacat aaatcgaaag gtcttgaagc agattacgta atactcttgc aatgcaataa
     9181 agacacttat ggcttcccat ctcttgtgag tgacgaccct gtgcttaact atgtactaac
     9241 taaaagcgac caattcccat atggagaaga acgtagattg ttttatgtag caataacaag
     9301 ggcaaagatg aaaactcttg tgctatatga caagcgtttc ccctctgtat ttgtggatga
     9361 atttttgcat cctgaaaagg tttcagaaga gagttatgtg aagcacccca acgccaataa
     9421 aagatggaca agaggtgcag accaatttct gttgaaacta tatagcgagg gtaagagcgt
     9481 gaggtatatt gccactaaaa tgggtagaag ccaaacttca attgttatgc gattgaataa
     9541 acttaatcaa taatacacaa tctctaaaat aagaataacg cacctcgtta atgtaatata
     9601 aaacacccaa ttttacattc ttgggtgtaa aattgggtgt ttgttttgca atttgctgat
     9661 tttcagtgtt tattgcggag agacagggat tcgaaccccg ggtacctcgc ggtacaacgg
     9721 ttttcaagac cgccgcaatc gaccactctg ccacctctcc aaaacttcct tatcagaagt
     9781 gcttttcgtt aaaagcggtg caaaggtacg aagatatttt aaacttgcaa gagttttcac
     9841 taaaaattta atctaatctt ttcctaagga tagcaattaa taggtatttt atgttgaaaa
     9901 gcataaaata gagcatattt atgctgatta tatgaaaaat gattgtaact ttgtgcgctc
     9961 taaagaatag gataactaca acctctaatt ttatcatttt atggaattaa acaagatctt
    10021 taaagacggt ctttggagca gcgaaatcaa cgtcagagat ttcgtaagtc ataacatcac
    10081 tccgtattac ggagatgctt cattcctcga aggacctaca gaacgtacca aagccgtatg
    10141 gaaccgctgc ctcgaagcac tggcagaaga aagagaaaac aacggtgtcc gctcattaga
    10201 taatgttacc gtatcaacca tcacttccca caaggccgga tatatcgaca aggaaaacga
    10261 actgatcgtc ggcctgcaga cagacgaact tctgaaacgt gccatcaagc ctttcggagg
    10321 tatcaacgta gtcagcaaag cctgtcacga aaacggcgtg gaagtggacg accgcgtaaa
    10381 agatattttc actcactacc gcaagacgca caacgacgga gtattcgacg tatatacgga
    10441 agaaatccgt tccttccgtt cgctgggatt ccttaccgga cttcccgaca attatgcacg
    10501 cggacgcatc atcggtgact accgccgtat ggctctttac ggcatcgacc gtctgatcga
    10561 agcaaagaag gaagatttgc acaacctcac cggtccgatg acagaggccc gcatccgcct
    10621 gcgcgaagaa gtggcagaac agatcaaggc actgaaagac atgaaagtga tgggcgaata
    10681 ctacggtctc gacctgagcc gtcccgctta cacggcacaa gaagccgtac agtgggtata
    10741 tatggcttac cttgccgccg tcaaagaaca agacggtgcc gctatgtcac tgggtaacgt
    10801 ttcttctttc ctcgatatct atctggaata tgaactgagc aaaggaacca tcaccgaatc
    10861 attcgcgcaa gagctgatcg accagtttgt catcaaactg cgtatggtcc gccacctgcg
    10921 tatgcaatca tacaacgaca tctttgcagg cgacccgacc tgggtaaccg aatctctggg
    10981 cggacgtctc aacgacggac gtaccaaagt gacaaagacc tccttccgtt tcctgcagac
    11041 attgtacaac ctcggccctt caccggaacc gaacctgacc gtactctgga gcccggaact
    11101 tccggaagga ttcaaagaat tctgtgcaaa ggtttctatc gacacttctt ctatccagta
    11161 cgaaaatgac gacctgatgc gcgaagtacg tcagtccgac gactacggaa tcgcctgctg
    11221 cgtatcatac caggaaatag gcaagcagat tcagttcttc ggcgcccgtt gcaacctggc
    11281 caaagccctg ttgcttgcca tcaacggcgg acgttgcgag aataccggta cagtcatggt
    11341 gaagaacatc cccgtactga ccagtgacac gctgaagttc gaagaagtaa tggacaacta
    11401 caaaaaagtg ctgaccgaaa tcgcccgcgt atataacgaa gcgatgaaca tcatccacta
    11461 tatgcacgac aagtattact acgagaaggc ccagatggct cttgtagata cgaacccgcg
    11521 catcaacctg gcttacggtg tagccggact ttccatcgcc ctcgattcac tgtctgccat
    11581 caaatatgcg aaagtaactg cccgccgcaa tgatatcggt ctgacagaag gcttcgacat
    11641 cgaaggagaa ttcccttgct tcggtaacga caacgacaag gtagaccacc ttggcgtaga
    11701 cctggtatac ttcttcagcg aagaattgaa gaaattgcct gtttacaaga atgcccgtcc
    11761 taccctctcc ttgctgacta tcacttccaa tgtgatgtac ggcaaaaaga ccggtgctac
    11821 tcccgacgga cgtgccaaag gtgttgcctt cgctccgggt gccaatccga tgcacggacg
    11881 cgacaagaat ggtgcgatcg cttctctgag ttctgtagcg aaacttcgtt accgtgactc
    11941 acaggacggt atcagcaaca ccttctctat cgttccgaaa tcactgggtg ctacggacga
    12001 agaccgtatc gagaacctcg tgacgatgat ggacggttac ttcaccaaag gtgcccacca
    12061 cctgaacgta aacgtactga accgtgatat gctgtacgat gccatggagc atccggaaaa
    12121 ctatccgcag ctgactatcc gcgtttccgg ctatgccgta aacttcgtga agctgagccg
    12181 cgaacaccaa ctggaagtta tcagccgtag cttccacgaa cgtatgtaat ctattactct
    12241 atatgatgat aaacgtacat tcatacgaaa gtatgggaac attcgacggg ccgggcttac
    12301 ggctcgtcgt ttttcttcaa ggatgcaact tccgctgcct ctattgcgcc aatccggata
    12361 cgatagcagg aaagggaggc acgcctaccc caccggaaga aatcgtccgc atggcaatga
    12421 gccagcgccc cttcttcggg aaacgagggg gaatcacttt ctccggaggc gaaccgacgt
    12481 ttcaggcgaa agcactcgtc ccgctggtcc gcgaactgaa agaaaaaggc atccatgtct
    12541 gtctggacag caacggagga ctttggaacg aagacgtaga agaattattc agactgaccg
    12601 atcttgtgtt attggatata aaggaattca accccaaccg ccatcagacg ctcaccggaa
    12661 gaagcaacga gcaaaccatc cgcacggccg cctggctgga agaacaggag aaacctttct
    12721 ggctacgcta cgtgctagtg cccggataca gcgattttga agaagacata cgcgcactgg
    12781 gagaagcact cggaaaatac aagatgatcc aacgggtgga aatactgcct taccatacac
    12841 tgggcgtaca taagtacgaa gcgatgggac aggaatacaa gatgaaaggg gtaaaagaaa
    12901 atacccccga acagcttgaa aaagctgcgg aggtattcaa agagtatttc actacggtgg
    12961 tagttaatta atggagaatt ctccaatgac ctcaaagcaa gggcattctt taatccgttc
    13021 ccaaggatct acgatcccat tatagttggt gtcgggactt aaatcccgat gccctactac
    13081 tttagcttcc ggataacgct gcaacaattc gtgtaccaag cgatgtagcg cctccttctg
    13141 acggggtgta cgcgtatccg cagcttttcc attctcatcc agaccgccct cataacatac
    13201 acctaagctg atcgcattat agccacgtgc atgagctccg accgtatctt catcccgcat
    13261 cggctcaatc tcgcccgact tgcgtatata ataatgatac ccccagcacg aaaagccacg
    13321 ataacggtga gccgtatcca catcctttgc cgtaaagtcg caatcgacac gggtggcgga
    13381 acaatggatc acaatcagac taatctttct catgttcctt ttccctttcc gtcgttttca
    13441 ctttgcacac ctccttacaa gtagtatgat agcgcacttc tctcaccacc ctgtcccgct
    13501 ttctctttcc gaagaaagga atcagataca tgatcacatc taaaatccga cttactattt
    13561 ctttcatctt atcaaaatat taatggaagt tattctaatt cgttattacc ttgacccgtc
    13621 tgccaattat accgtagggt ccggagcctc ttcatcaccg gagccatcac caccggaatc
    13681 cggattcttg tcagggtctt ctcccccgcc atcgcctgca cccgcctgcg ccaccgcacg
    13741 agtctgcact tgctgataac tcagaatctt catcaactcc gccagcgtct taccggggcg
    13801 gaaaataaga tgcgccccct taatcattga accggaaaat tccttgaccg atgccgcacc
    13861 ttcactgttg agtcctatct gcaaactgcc caaatcgccc agtctcgcaa ttcttcctgc
    13921 cttcaacgca cgcttcactt cgtaaagaat acccgaaata gccgcacgta catccgtttc
    13981 cgtacaagta gaacgactgg tgatcgcttc gcacaactct tcaaagtcca actctcccga
    14041 cgcctgcgcc tgtgcataat actttgccgg ttcgctcttt tttgcaggat tcttgcgcgg
    14101 caccactgaa taagatactg tcattgccat aataaaataa ttttaaagtt tataatacat
    14161 aggatgcatc cccttcttgt taacagcaca aagataagga tagccggaca agccatattc
    14221 cccaacgaag tttcttgatt cccaacgaat aaaaacgaag tcaaaccttt gaataacaag
    14281 gaattttatg taactttata gcataaaaca agaagaaaac atcatgaatt acaaagaaga
    14341 ttctttcctt atccgcacct ataccaaagc ggaactggct cacctttaca atccccatgt
    14401 ctgcctcaaa gttgctttac aaatacttcg tcgttggatt atttacaacc tccctctcct
    14461 gcacgaactc gaacaggaag gctaccgcgc acgcaaccgt ctcctttcgc cgaaacaagt
    14521 ggcaactatc atacactttt tgggcgaacc gtagtaactt attgccattt tatacaaagt
    14581 tcctttacac atttccgcaa agaagttcct ttgcatcgac aaacaataat caaaataaaa
    14641 atgaaacatt tcaccatatt tcaaggtttc tactacgcaa tagcagagat gaccgaagaa
    14701 gaaatagtgt ccactatcgg cagttttacc taccgggaaa aagtcgaaga aatacgccgc
    14761 atctttgcag agcaaggaga aaaggctgcc aatgagaaga aaaaagaatt gccggcaatc
    14821 gccttctccg ccagctaccg aggaaggcgt accaaagtga acctcgtcaa atatctggga
    14881 cacatcgtga tagacatcga ccacctcagc aaagaagaat tggcacgcat cctccctatc
    14941 atcaagagat gcgattacac ccgcatcgcc tttatcagcc ccaaagggat gggcgtgaaa
    15001 atcatagtac gcgcatgcca tccggatgag acattgcccg aaacccttca ggaaatagaa
    15061 gacttccatc atgcagctta caccagactc gtttcttttt acaccgaact ctgtcagata
    15121 gaaatcgaca cctccggtca ggatgtggca cgcacttgtc tgttctctta cgatccggag
    15181 atttatttca atccgaacgc tgacgctttt cttgtagatc aacctcaggc atcctacaag
    15241 gtttcaaatc gtaaaaatct ctccggcagt aaacaacaga ctcctccgga cggccccccg
    15301 acgaatgaag acacagcgct caacgcccat tccgccaacg cttctctggt gctgacttta
    15361 acctactatc acaacaagtc cgaaaaatac atagtgggca accggaacaa ttatctgcac
    15421 catctctcat gtaccttcaa tcgctacggc attccgcagg aggaagcatc cgcctttatc
    15481 aaaagccagt ttacagactt tccggcggac gagacagcct ctttgatcaa tagcgcctac
    15541 gctcataccg acgaatttaa tacctgtaag ctaaatggca cgcagaaacg aatattacgg
    15601 atagagcaat atatcagcga gcactacgaa acacgctaca acgaagtgct gcatatcatg
    15661 gaatatcgca gaaggcatcc cgacaccgag aaaccggagc ctttccgcat cttggatgag
    15721 atgatggaaa acagtatctg gatagaaatc aacgaactgg gatatgcctg cactgtcaaa
    15781 acaatcgaaa atctgattta ctccgatttc agccagtcgt atcatcccat tcgcgagtat
    15841 tttgaattac tgcccgaatg ggacggaacc gactatatcc gtatcctggc ggatagtgtc
    15901 cagacgagtc atcaggagtt ttgggcggaa tgcctggaac gttatctggt ggcgatgtgc
    15961 gcagcggcta ctcaagagaa tattgtcaat cacacggtac ttctgctatg cagcgagata
    16021 cagaacatag gaaagactac ctttatcaat aatctcctgc ctcccgaact gcgtgcttat
    16081 ctctctaccg gactaatcaa ttcgaacaat aaagatgatt tagccaaaat aacgcaggcc
    16141 atgctgatca atctcgacga gtttgaaggg atgagcggtc gggaactgaa tgcattcaaa
    16201 gatttggtaa cgcgcaaagt gatcagtttc cgtctgcctt atgcacgccg ttcgcaaaac
    16261 ttccctcata cggcctcttt tgcaggaacc tgcaattatc aggaagtgct tcacgacacg
    16321 acaggcaacc ggcgtttcct ttgttttcat ccttattcca tccaatttat taccatcaat
    16381 tatgcgcagc tctatgctca gatcaaatat ctgctgaata agccgggata tcaatactgg
    16441 ttcacgcaag cggacaatga acggcttgaa gagaataacg aggctttcat ctttcattca
    16501 ccggaagaag aaatggttct tacgcatatc cgcaagccgg aacgtttcga gaaggtttat
    16561 tatctgactg tcagtgagat tgcggaacta atacgtgagc gtaccggtta tcagtattcc
    16621 atcggatcaa aaatacagtt ggggaaggtg atgactaagc accattttga atctaaaaaa
    16681 ggaaataacg ggcgccgata tgccgtattt attatagata tcgagcaggt aaaatcaaac
    16741 aggctgtatg aatagaagcg ggaaagcctt gtgaatatag caaaatgcag agtcatcttg
    16801 acagatactc tgcatttatt gtttttacaa aatcattgaa aattcgattt tacagcctaa
    16861 cgcattcatt atacgataga aagtagatac tttaggctct gtctgaccac tttctactct
    16921 tgaaatataa gaacggtcag agccgatacg ccgggctaat tcagcctgag tgattttagc
    16981 cttttttctt gcgtcctcga taatctgtcc tgtataaaag gcgtaggcct tttcttctgc
    17041 ctctgcacga gaagctgttc cttccttacc aaaacgctca tctattaatg cactgacatt
    17101 aaagaattcc tcatttgttt ttgcttccat aatactcctt tcttaatatc tttgctttat
    17161 caatttcttt ctttggtgtt ttttcggttt tcttttgaaa accgttaaac agaatcacaa
    17221 tacgcccttc gtcgaaacaa aagaatattc tatatatatt gctttggtac tcgatacgaa
    17281 gttcataaag tccttcttct atcaaccgca taaatttcaa aggtattctg tcttgtgtct
    17341 gcaataacat tagcacatac aatatcttat cttgggtgcc agcatctaaa ttttcaaaga
    17401 attctttgaa gtatccttta tatgctatta tttctctttt cataacgcaa atataagaaa
    17461 tgttgttcaa ctatacaaca tatttcctcg ttttatatta tttttcatca tcttcacccc
    17521 caaaagtgag aggagtgaga gaggaattga aactttttct attttatttc tttatttcta
    17581 ctttctatat ttctctaaaa aaaatacgaa tgttaga
//
