LOCUS       gnlProkkaGIHHDPPA_42    8897 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GIHHDPPA_42.
ACCESSION   gnlProkkaGIHHDPPA_42
VERSION     gnlProkkaGIHHDPPA_42
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 10:43:26
            Original ID  :: gnl|Prokka|GIHHDPPA_42
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8897
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1512
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 75.1;
                     E-value: 6.6e-23)"
                     /gene_kind="transport"
                     /locus_tag="ctg42_1"
                     /transl_table=11
                     /translation="MIVPAYDVLVKISGKVKRPMRFEMKKDENLATLIKYAGGFEADAY
                     TRSLRVVRQNGEEYEVNTVKDMDYSIYTMRNGDVVTAEAILNRFTNKLEIRGAVYRPGI
                     YQLSGKLNTIRELVNEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGTSPNLA
                     LMKNDILYIPSIHDLEDRGNVTVHGEVAQPDSYPYADNMTLEDLIIQAGGLKEAASTVR
                     IDVSRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILQPYDQVYVRRSPGYQAQQ
                     NVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKKRMGDV
                     IRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIPKNTNT
                     VTINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKGSGKKQ
                     IEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     protocluster    1..8897
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2734:7048]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2735..7048
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..8897
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8897
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             1523..2671
                     /locus_tag="ctg42_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             2735..3454
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.1e-16, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             3475..4776
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_4"
                     /sec_met_domain="CTP_transf_like (E-value: 1.4e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.4e-121, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.6e-63, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             4793..5917
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 7.5e-21, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.5e-21, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             5927..7048
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2e-33.
                     Score: 107.6. Matches aSDomain:
                     nrpspksdomains_ctg42_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 74.1; E-value:
                     1.7e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_6"
                     /sec_met_domain="Aminotran_5 (E-value: 8.4e-31, bitscore:
                     96.4, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLPYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        6017..7024
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg42_6_Aminotran_5.1"
                     /evalue="2.00E-33"
                     /label="ctg42_6_Aminotran_5.1"
                     /locus_tag="ctg42_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="107.6"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLPYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             7045..7188
                     /locus_tag="ctg42_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             7391..8875
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_8"
                     /sec_met_domain="Polysacc_synt (E-value: 9.5e-32, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             8829..8897
                     /locus_tag="ctg42_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDS"
ORIGIN
        1 gttatcgtcc ccgcctacga tgtcttggta aagatcagcg gcaaggtaaa acgccctatg
       61 cgtttcgaaa tgaagaaaga cgagaacctt gccactttaa tcaaatatgc cggcggcttt
      121 gaagccgatg cctacacccg ttcattgcgt gttgtccgtc agaatggtga ggaatatgaa
      181 gtcaacacgg tcaaggatat ggactacagc atctacacaa tgcgtaacgg cgacgttgta
      241 acagccgaag ccattcttaa ccgcttcaca aacaaactgg aaatccgtgg cgctgtctat
      301 cgtcccggca tctaccagct cagcggtaaa ctgaatacga tccgtgaact tgtcaatgaa
      361 gcccagggcc tgaccggtga cgctttcctg aatcgtgccg tcctttatcg ccagcgtgag
      421 gatttgacca gtgaagttgt tcagatagac atcaagtcta tcatggacgg tacttccccg
      481 aaccttgccc tgatgaagaa tgacatcctt tacattccga gcattcacga tctggaagat
      541 cgtggcaatg tcacagttca cggtgaagtc gcccaaccgg attcctatcc ctatgctgat
      601 aacatgacac ttgaggatct gatcatccag gccggtggct tgaaagaagc cgcctctact
      661 gtccgcattg atgtgtcgag acgaatcaag aatccccgta gtactgcgga taatgatact
      721 atcggtcaga tgtatacctt ctctttaaag gatggttttg tcatcgacgg tcagcccggt
      781 tttatccttc agccttatga tcaggtttat gtccgtcgca gtccgggcta tcaggcacaa
      841 cagaatgtag ccattgaagg tgaaatcctt ttcggaggaa attacgccat gaccagccgt
      901 gaggaacgtc tttccgattt agtgaataaa gccggcggtc cgaccaatta tgcctatctg
      961 cgtggtgcga aactgacccg tgtggctaac gctagtgaaa agaaacgtat gggtgatgta
     1021 attcgcctta tgagcaggca attgggcgaa gccatgattg actctttggg tattcgtgtt
     1081 gaagatactt ttacggttgg aatagatttg gaaaaagcct tgagcaatcc taaaagtaat
     1141 gccgatcttg tcttacgtga aggtgatgtg atctccatac ctaagaatac taatactgta
     1201 actatcaatg gtgctgtcat ggttccgaat acggtttctt atatgaaggg aaagaatgtg
     1261 gattattacc tgaatcaggc cggtggctgt tctgataatg caaggaagag taagaagttc
     1321 attgtttaca tgaatggtca ggtgacgaag gttaagggta gtggtaagaa acagattgag
     1381 ccggggtgtg agattattgt gcctggtaag gctaagaaga aagggaacat agctaatatt
     1441 ttaggttatg ctacttcctt cagttctttg ggaatgatga ttgcttctat tgctaatttg
     1501 ataaagaaat aaatgaccta ttatgattga aaagcaatct tatcaagaac cgttttctga
     1561 agtggataaa aggaaagatg atgaaatgga aatagacttg atggctattt tttataagat
     1621 tattactgtt cgtggagtac tatgcaaagc tgctggagtg ggagtaataa ttgctatagt
     1681 ggtggcattg agcattccca agcaatatac agtaaaggtt accctttctc ctgaaatggg
     1741 taatgcgaag ggaagtaatg gtttagccgg acttgctgcc tcgtttttgg gagatggggc
     1801 tctaataggg gaaagcacag atgccttgaa cgcttctctt tcagcagata ttgtttcttc
     1861 aactcctttt ttattggaac ttttagaaat ggaagtctcc gtttctaaaa aggatgataa
     1921 aatgactttg gggtcttatc tcgatgaaga gtcatctcct tggtgggatt atcttatagg
     1981 ttttccgggc atagtaatag gaggagttaa atcattattc ggagaagata cggttcctgc
     2041 cagtggaggg cggcaaggaa ctatcgaatt gacgaaagaa gtaaatgaga agattaattt
     2101 tcttaaaaag aagattagtg catccattga taagaaaacc gccataacga gcattacggt
     2161 caccttacaa aatccgcaga tcactgcggt tatagcagat tctgtcgttc ataaattaca
     2221 ggaatatatt attgggtatc gaacttcaaa agtaaaagaa gactgtgcgt atttggaacg
     2281 gttgtttaaa gaacgtcagc aggaatatta tgctgctcaa agaaaatatg cggattatgt
     2341 agacgcccat gataatgtgg ttcttcaaag tgtacgtgct gagcaggagc gtttacagaa
     2401 cgacatgagt ttggcttatc agatatatag tcaggttgct aatcagttgc aggtatccag
     2461 agccaaagta caggaggaaa agccagtctt tgcagtagtt gagcctgccg ttgtaccttt
     2521 gaaaccttca ggtatgggac tcaaaattta tattttatta tttgtgttcc tgtccgtatc
     2581 tggtactctc gtgtgggtgt tttttggcaa aagtctgctg gctagcttga gaaaagaact
     2641 gaaaaataag gagatagaac aggataaatg atgctaaaac gtcgtttaca acattcttac
     2701 atcaattaaa ttcacttact atattattaa acgaatgata cgtacagcta tgataatggc
     2761 tgcgggcatg ggaacccgtt ttggccaata tacagaattg atacctaaag ggttcgtcaa
     2821 agtgggaggt attccaatga tagttcgttc tattgatact ttgttatcat gtgacattga
     2881 gcgaattgta atcggtacag gatataaaca agaagtttat gaagaattga agacagacta
     2941 tcctatgctt gaaacctgtt ttagtcctcg ttatgctgaa acaaatagta tgtatacttt
     3001 atataatacg cgggagattc tgggcaatga tgatttttta ttgttagagt cagatttgat
     3061 ttttgagaaa caagcaataa tgagcttatt ggagtgtcct gcggcagatg caatgctaat
     3121 aactccagtg acaaagtttc aagatcagta ttatgtggaa catgatgata attttcgcct
     3181 ttcttcatgt tctgtcaata agaataaact aaacgctaaa ggcgaattgg tcggcatcca
     3241 taaactatcc ggttcctttt acaaaataat gtgtgctgat tatgcgagta ttgttgatga
     3301 acaacccaat ttgggatatg agtatgaatt actacgaata tcttgttctc aatctcctgt
     3361 ttatgtgcat aaagtagaag ggctgaaatg gtatgaaatc gatgacatat cagatttgga
     3421 atatgcagag aaatatattg ttccgtattg ttaattaaaa taatatatca aattatgagt
     3481 aagacagttt atattgggat gactgcggat attatgcatc caggacttat ccgcattatt
     3541 aatgaggcta ctaaatacgg tgatgttata attggtcttc ttacagataa agctattgcg
     3601 gagcataaac gccttcctta tctgacctat gaacaacgaa aagaggtagt tcagaatatt
     3661 aaaggcgtat gtaaagttgt tcctcaagaa gaatggagct atgttgagaa tctcaaacgc
     3721 attaaacctg actatataat tcatggtgac gactggaaaa ccgggccttt acgtgaagaa
     3781 cgtgtgcgcg tatttgaagt gatgaatgaa cagggaggaa aggttatcga aattccatat
     3841 actttgggaa ttaattcatc ttctttggat aaagatatta aggctatagg tacaacccct
     3901 gatgtacgtt taaaatcact tcgtcgtttg ataaatgcca aacccgtagt tcgtattttg
     3961 gaagctcatg atggactatg tggcttgata attgaaaatc aggaaatatt aaaaggggat
     4021 aagagggaag tatttgacgg aatgtggtct agtagcctta cggattcaac cagtaaaggt
     4081 aaacctgata ttgaggcggt tgatttaact acccgattgc aagatttgaa taatattctg
     4141 gagtgtacta ctaaacctat tatttttgat ggagatacag gtggtaaaat tgaacatttc
     4201 gtatttacag tacgcacttt agaacgtcat ggaatttcag ctataataat tgaagataaa
     4261 gttggattaa aaaagaattc attgtttggt acagatgtta ttcaaactca agatacaatc
     4321 gaaggtttct gtaataagat caaagcagga aaggcatctc agattactga tgattttatg
     4381 attatcgctc gtattgagag ccttatagcg ggaaagccgg taagtgatgc tttagagaga
     4441 gcttttgcat atgtccaagc gggagcggac ggtattatga tacatagcaa aaataagtcg
     4501 ggtgaagata taaaagaatt ttgtttggcg tttcgaaaac agtatgctca tgtacctatc
     4561 gtggttgtgc ctactacata tgatcatatt tatgagtctg aattgtgtga ttggggtgtg
     4621 aatataatta tttatgctaa tcatatgctt cgtgccgctt atcctgctat gatgaatgtc
     4681 gcaaagataa tattagagaa tgaacgtgct ttagaggtgc gcgaactgtg tatgcccata
     4741 aaagaaatat tggaactgat tccaggtact aaataaaaag aggaatatca ttatgttaag
     4801 cgtagaaaaa gtttatgaaa cgtttctgag tcatgacgtt gattttttta caggagttcc
     4861 agactcatta ctaaaaaata tttgtgccta tatcacagac catacttcac gtgagaaaca
     4921 tatcatagct gctaatgaag gtgcggctgt aggaattgct tcaggttatt atatggcatc
     4981 aggtaaggtt cctgtggttt atatgcaaaa ttccggcttg ggtaatactg ttaatcctct
     5041 gctgtctctt gcagatgaac aagtatacag ttttccaatg cttttgatga ttggctggcg
     5101 tggtgaaccg ggaacaaaag atgaacctca gcataaaaaa cagggtgagg taactttaga
     5161 tttgttgaaa gcaatgcgga ttccttatat aattcttgat tcaaatgaga atgatgcatt
     5221 tattcagctc catgatatca tacaatcagc aaaaactaag aatattcctc atgcaataat
     5281 tattcggaaa gatgtttttg gcaaatataa acttcaaaaa gagttcggat gtaattatcc
     5341 tttatctcgt gaggatgctt tgcaaatagt tgtggattat ctgcctgaaa attcagtggt
     5401 cgtttctact actggcaagc tttctcgtga gttatttgaa tatcgagaaa tgaaagagca
     5461 aggtcatgaa catgattttc tcacggtagg ctctatggga catagttcat caatctcttt
     5521 gggtattgct atagcaaagc aagatagacc tgtttattgc ttggatggtg atggagcatt
     5581 tattatgcat ttaggggcaa ttagtaacat tggcgattta tctcctaaaa actattatca
     5641 tattttgttt aacaatggtg ctcacgagtc tgtaggagga cagcctactt taggatttag
     5701 tttagatatt ccggctattg tccgggggag cggatataag catacttata ctgtttgtac
     5761 aaaagttgaa attgaagaag caatgaagca gcttccaaag ttatgtggtc ctgttttgtt
     5821 ggaaataaag gttaaaatag attctcggga gaatttggga cgtcccacga ctactcctat
     5881 agagaataag gagcatttta tggatttttt aaaataaata tattcgatga aaatagaaag
     5941 aaaaatatta ttaaatcctg ggcctgccac tactactgac agtgtaaaaa tggcacaagt
     6001 tgttccggat atttgtcctc gcgagaaaga attcgcaggt atgatgaaac aacttcggga
     6061 cgatttggtc agagttgctc atgggaattt ggaaaaacat accgctgtat tattttgtgg
     6121 ctcaggaacc atcaatattg atatatgtct aaattctctt cttcctgaag acaaaagggt
     6181 gcttatagtg aataatgggg catatagtac ccgtgctgta gaagtgtgtc aatattatgg
     6241 tttgcctcat attaatttgg aattttccgt ttacgaacgt cctgatttat cggtggtgga
     6301 aaatgtgttg caagaaaatc ctgatatagc tatggtttat actactcatc acgagacggg
     6361 tacaggaatt ctgaacccta ttcgcgagat gggcgctata gctcataaat atcaggctaa
     6421 atttgtcgtc gatactactt cttctttggg catgattcct tttgatatag agaaagataa
     6481 tgtggatttt tgtatggcat ctgctcaaaa aggacttcaa gcgatgacag gtctttcttt
     6541 tattataggc aatgaggaac agattaagtt ttcaaaaaaa tatcccaagc gttcttacta
     6601 ttgtaatctt tatttgccgt atgagaattt tgagagaaca ggtgaaatgc attttactcc
     6661 accggtacaa actatttacg ccactcgtca ggcattaaat gaatattttg aagtgggtga
     6721 agaagctaag tttgcccgtc acaaaagagt ttttgaggct attcattcag gtataaatga
     6781 aattggtctt aaaagtgtaa taaagcgtga atggcagtca ggactggttg tctcagttca
     6841 atacccagaa gatcccaact gggattttga gaaaatacat gattattgtt atgagcgtgg
     6901 atttacgatt tatccaggta agatatcaac tgaggatact tttagaatct gtgctttagg
     6961 agagatagaa gtagatgata ttgagaactt ctttaaagta ctaaaagctg cattaaatca
     7021 ttataacgtc acattaccga tgtcatgatt gcagaaatat tattgaagat tcgtcatttt
     7081 tatttttccc ttcgtggtat acacttccat ccggaaagtg ttatttctgg agtgcctatt
     7141 cgtagctttc gcttagtagg caaatatggc aatattaatt tgaggtgatg cattaggagt
     7201 tctttattct tataaaaagg catcggtagt tataggagat aatgtttgtg tagggtaatt
     7261 tgcttttagt gggagagacc atattagaat tgcggtaagg ggcgaagaag ataataacca
     7321 attagtgaga atattggaaa aatataattg atatcggtaa atgtagttgt ttttatactg
     7381 tatttaagta atggaaaatc taaagcagaa aactgtatca ggaataatgt ggagcgctat
     7441 agaacgtttc tctttacaag gagtacagtt tataattcaa ataatattag ctcgtttgtt
     7501 actaccatcg gattatggta tgatcgggat gttagctatt tttcttcaag tcgctcaagt
     7561 atttatagat agcggtttta caaatgcttt aatccagaaa aaagatagaa ctgaagagga
     7621 ttttgccact gtcttttatt ttaatattct tgtcgcagta ttattctatg gtatattgtt
     7681 tttttcggct tctttgattg cagactttta taatatgccg actttagttc ttgtaattcg
     7741 ttttatagca ttgtcgttga taataaatgc tttatcggct attcacagaa cgaaattaat
     7801 tatttctgta aactttaaaa ctcaatctaa aatttcatta ggtgcagctt ttatatcagg
     7861 cgtgattgga atatggatgg cttatgtcgg ttgcggggtt tgggctttag tttggcaaac
     7921 tctcttaaat agtataattt tgacaatttt gttttactgt ttagttcatt ggaaaccttt
     7981 acatactttc tccaaaagtt cttttgaaag attattcaat ttcggatcta aattattgat
     8041 ctcaagtctt atcaatacag tatatcgtaa tctgtatacc attgtaatag gaaaaaagtt
     8101 ttctgttgta gagcttggtt actatacaag agcagaacaa tttgctattt ttccttccaa
     8161 taatttaaat gctttagttt ctagagtagc gtatcctatt ttaagttcca ttcaagatga
     8221 tgataaatgt ttaacaaacg catatcgaaa ttatatcaga ttatcctcat atataatttt
     8281 tcctttaatg gtaggtttac ttgttttggc taatcctatt attagtctat tgttaacaga
     8341 taaatggtct ggggttgtta ttcttttaca gatattatgt ttggattgga tgtttgatca
     8401 tttgagccaa attaatttga atttattatg ggttaaagga agatctgatc tgtcgttacg
     8461 tcttgaaata ataaaaaaga cgattgctat attcattctt tttgtgtcaa ttccatttgg
     8521 gcttgaggtg atgtgttggg gtagagttat ttactctctg atagcgacat atttgaatac
     8581 atattatact aattctctta ttgatttgac cttaaagttg caagttaaag atgtatttcc
     8641 aagtttaata ctctctttca taatgggggg gatcgttttt atatgtattt ctttctttga
     8701 aactgatata gtaaaaattg tgattggatg tattactggg atgtccttct atattttact
     8761 ttcttttctt tttaagctag attctttttt ttgtatttta acattgatca ttaaaactaa
     8821 aaacatagat gaaaatatta aaaaagattt ttcaagtaat agtaaagata attaaccatt
     8881 gtgtgccagt tgatagt
//
