LOCUS       c00066_gnlPro..        17541 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GIHHDPPA_66.
ACCESSION   c00066_gnlPro..
VERSION     c00066_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 18:40:13
            Original ID  :: gnl|Prokka|GIHHDPPA_66
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17541
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17541
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4570:7541]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4571..7541
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17541
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17541
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             99..431
                     /locus_tag="ctg66_1"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLMLLQTQDRIPLKFM
                     RLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIDKAKILRKEY
                     YGSKNK"
     CDS             412..717
                     /locus_tag="ctg66_2"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(787..2901)
                     /locus_tag="ctg66_3"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     NYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIAGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETVSLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(2988..3218)
                     /locus_tag="ctg66_4"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             3412..3915
                     /locus_tag="ctg66_5"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             3975..4142
                     /locus_tag="ctg66_6"
                     /transl_table=11
                     /translation="MKEIVNRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             4282..4578
                     /locus_tag="ctg66_7"
                     /transl_table=11
                     /translation="MRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEAL
                     HRLVHELLQRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(4571..5299)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.5;
                     E-value: 1.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_8"
                     /sec_met_domain="Radical_SAM (E-value: 1.3e-28, bitscore:
                     92.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(5313..7541)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_9"
                     /sec_met_domain="Gly_radical (E-value: 4.3e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             8193..9398
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 94.2; E-value: 2.6e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg66_10"
                     /sec_met_domain="MFS_1 (E-value: 2.9e-29, bitscore: 94.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHWKSTLAVIGIGQLISILTSTIVGFSIIFWISNEFKSPTALSL
                     AILAGFLPQFVLGLFAGVYVDRWNRKKTMFYSDLFIAFCTLCLFIVITKGYKDLSFFYL
                     LTACRSIGSTFHAPALQASIPLLVPKHHLVRVSGLYHSIQSFSEVIAPVVGASLVVWLP
                     IQYILLIDVIGAVAACLTLLCVQIPSLQKTKVLPDFKKELTECWHTLRRTMGILPLFVC
                     FTLVTFVLMPVFTLFPFMTLLHFNGNILQMGVVEMGWGSGALLGGLVLACKALKSKQTL
                     VMHTAYVILGLYLISASYLPSSAFIGFVCLTFTGGIAYSIYHALFIAIIQQNLASDMLG
                     RTFSLIFSLSTFPSMLGIVASGYWVEAWGITSVFMISGWVIFLIGVGANFISSIKQLDN
                     YA"
     CDS             9423..9935
                     /locus_tag="ctg66_11"
                     /transl_table=11
                     /translation="MTKKEHTTITELFQVLDLLESLDMQFWLDGGWGVDVLYGQQTRLH
                     RDIDIDFDANYTDQLLDLLQERGYQIETNWLPTRVELYSKELGYIDIHPFVLNADGTSK
                     QADLDGGWYEFQPDYFGTAVFEGRSIPCISAKGQQVFHSGYDLREKDIHDLSIIKQCIT
                     TMSLTIR"
     CDS             9946..10089
                     /locus_tag="ctg66_12"
                     /transl_table=11
                     /translation="MTEKQIVWYILLTEVKIDSDTQSVTSLSVAPLAVLPEFQRKGIGG
                     GC"
     CDS             complement(10382..10735)
                     /locus_tag="ctg66_13"
                     /transl_table=11
                     /translation="MKPKEVLEKWIDCFNKADAYHIAELYATNAVNHQVANEPIIGKES
                     IYKMFVNEFATAKMVCMVENIFEDGEWAIMEWKDSLGLRGCGFFHVKDNKIVFQRGYWD
                     KLSFLKQHNLPIE"
     CDS             complement(10824..12227)
                     /locus_tag="ctg66_14"
                     /transl_table=11
                     /translation="MATKSSIHIKPCNIASSEAHNRRTAEYMRNIGESRIYVVPELSTD
                     NEQWINPDFGTPELRTHYDNIKQMVKEKTGRAMQEKERERKGKNGKIIKVAGCSPIREG
                     VLLIRPDTTLADVRKFGEECQRRWGITPLQIFLHKDEGHWLNGQPEAEDKESFQVGNRW
                     FKPNYHAHVVFDWMNHETGKSRKLNDEDMATMQTLASDILLMERGQAKAVTGKEHLERN
                     DFIIEKQKAELQRIEETKRHKEQQVSLAEQELKQVKAEIRTDKLKKTATNAATAIASGV
                     GSLFGSGKLKELEHHIEQLHQEITKRDKATDELKIQIQQIQEQHSRQIRNLQRIHNQEL
                     EAKDKEISRLSTLLEKAHKWFPMFKEMLRMEKLCAVIGFTKDMIENLLTKKESIQCSGK
                     IYSEEHRWKFDIKNDIFRVEKHPMDSGKLMLTINRQPIVQWFKEQWEKLQQNLRNSVQR
                     EQKSRGFRI"
     CDS             complement(12439..13398)
                     /locus_tag="ctg66_15"
                     /transl_table=11
                     /translation="MDIQTAKQIRIADFLYSLGYSPVKQQGINLWYKSPLREETEPSFK
                     VNTERNQWYDFAIGKGGNIIALAQELYCSDYVPYLLQKIEEQIPHIRPVSFSFGKQSFS
                     EPSFQQLDIVLLASPALLAYLQERGINTALAKRECKEARFTHNGKRYFAIAFPNISGGY
                     EIRNRYFKGCIAPKEISHIRQSGKPRSTCYVFEGFMDYLSFLTLRLESCPQSPDFDRQD
                     YIVLNSVANVPKALYPLGSYERIHCFFDNDRAGMEAIQQIRKEYDATRYIRDASQIYSG
                     CKDLNEYLQKRIADRKEQAQSVEKRNDTLSKKPKGFRL"
     CDS             complement(13615..14691)
                     /locus_tag="ctg66_16"
                     /transl_table=11
                     /translation="MDYMKEIKEISAEQAIILWQASRLSLSKIYEKAPEILKVQGSVIG
                     TLGNFSASIGKAKSKKTFNVSAIVAAALKNGTVLRYVAELPEEKRKILYVDTEQSHYHC
                     LKVMKRILRLAGLPDDRDNEHLEFLALRKYTPEQRIRIVEQAIYNTPDIGLVIIDGIRD
                     MVYDINSPGESTRIISKLMQWTDDRQIHIHTILHQNKGDENARGHIGTELNNKAETVLL
                     VEKDKSNGDISNVSAMHIRAMDFEPFAFRINDNALPELIEGYRPEAKKPGRPEEEKFDP
                     YRHISEQQHRIALEAAFGLKEEYGYKDLETSLIKSYMSVGVKLNHQKAVSLITMLRNKR
                     MIVQENGRKYTFKPDFHY"
     CDS             complement(14706..15014)
                     /locus_tag="ctg66_17"
                     /transl_table=11
                     /translation="MTNIQELLSKPVWQMTGEEFIFLSKHASGQAEALPQPVTDTEKKY
                     VYGILGIAKLFGCSLPTANRIKKSGKIDKAITQIGRKIIVDAELALELAGKKTGGRK"
     CDS             complement(15238..16257)
                     /locus_tag="ctg66_18"
                     /transl_table=11
                     /translation="MAGKIQTMIPQYGELNRIYRDYIDNYAFSFDRQKFISDFYQEYND
                     MKSFEAAILELVLDKQKEQYTLILNSLKTEIEKSIQAYEIRPLSDRAIERACYQHMERY
                     SQEIEAQLDVTRSLSKPLNEANNRYDSIGYREHTAEEEKQAEKEYERCKAEYDREKAKL
                     NKLYDQQKAARTEAFQYMKNCCADIYRQSCLFLDILKKYIPDGKQENKSSEPISQQETT
                     EEQQEYFSMKLLSLIHEVCIGEQFEEISALDFYANMNLHPCNCKLKIKPREKIRVCYLI
                     FLMSEKLSKQDRDKWKDRILKLLDIDDSYYKSKYKEPVSDFPSDSNQNFAKEMEHIFR"
ORIGIN
        1 ctctcactcc tctcactttt gtgggtgaag atgatgaaaa ataatataaa acgagggaat
       61 atgttgtata gttgaacaac atttcttata tttgcgttat gaaaagagaa ataatagcat
      121 ataaaggata cttcaaagaa ttctttgaaa atttagatgc tggcacccaa gataagatat
      181 tgtatgtgct aatgttattg cagacacaag acagaatacc tttgaaattt atgcggttga
      241 tagaagaagg actttatgaa cttcgtatcg agtaccaaag caatatatat agaatattct
      301 tttgtttcga cgaagggcgt attgtgattc tgtttaacgg ttttcaaaag aaaaccgaaa
      361 aaacaccaaa gaaagaaatt gataaagcaa agatattaag aaaggagtat tatggaagca
      421 aaaacaaatg aggaattctt taatgtcagt gcattaatag atgagcgttt tggtaaggaa
      481 ggaacagctt ctcgtgcaga ggcagaagaa aaggcctacg ccttttatac aggacagatt
      541 atcgaggacg caagaaaaaa ggctaaaatc actcaggctg aattagcccg gcgtatcggt
      601 tctgaccgtt cttatatttc aagagtagaa agtggtcaga cagagcctaa agtatctact
      661 ttctatcgta taatgaatgc gttaggctgt aaaatcgaat tttcaatgat tttgtaaaaa
      721 caataaatgc agagtatctg tcaagatgac tctgcatttt gctatattca caaggctttc
      781 ccgcttctat tcatacagcc tgtttgattt tacctgctcg atatctataa taaatacggc
      841 atatcggcgc ccgttatttc cttttttaga ttcaaaatgg tgcttagtca tcaccttccc
      901 caactgtatt tttgatccga tggaatactg ataaccggta cgctcacgta ttagttccgc
      961 aatctcactg acagtcagat aataaacctt ctcgaaacgt tccggcttgc ggatatgcgt
     1021 aagaaccatt tcttcttccg gtgaatgaaa gatgaaagcc tcgttattct cttcaagccg
     1081 ttcattgtcc gcttgcgtga accagtattg atatcccggc ttattcagca gatatttgat
     1141 ctgagcatag agctgcgcat aattgatggt aataaattgg atggaataag gatgaaaaca
     1201 aaggaaacgc cggttgcctg tcgtgtcgtg aagcacttcc tgataattgc aggttcctgc
     1261 aaaagaggcc gtatgaggga agttttgcga acggcgtgca taaggcagac ggaaactgat
     1321 cactttgcgc gttaccaaat ctttgaatgc attcagttcc cggccgctca tcccttcaaa
     1381 ctcgtcgaga ttgatcagca tggcctgcgt tattttggct aaatcatctt tattgttcga
     1441 attgattagt ccggtagaga gataagcacg cagttcggga ggcaggagat tattgataaa
     1501 ggtagtcttt cctatgttct gtatctcgct gcatagcaga agtaccgtgt gattgacaat
     1561 attctcctga gtagccgctg cgcacatcgc caccagataa cgttccaggc attccgccca
     1621 aaactcctga tgactcgtct ggacactatc cgccaggata cggatataat cggttccgtc
     1681 ccattcgggc agtaattcaa aatactcgcg aatgggatga tacgactggc tgaaatcgga
     1741 gtaaatcaga ttttcgattg ttttgacagt gcagggatat cccagttcgt tgatttctat
     1801 ccagatactg ttttccatca tctcatccaa gatgcggaaa ggctccggtt tctcggtgtc
     1861 gggatgcctt ctgcgatatt ccatgatatg cagcacttcg ttgtagcgtg tttcgtagtg
     1921 ctcgctgata tattgctcta tccgtaatat tcgtttctgc gtgccattca gtttacaggt
     1981 attaaattcg tcggtatgag cgtaggcgct attgatcaaa gagactgtct cgtctgccgg
     2041 aaagtctgta aactggcttt tgataaaagc ggatgcttcc tcctgcggaa tgccgtagcg
     2101 attgaaggta catgagagat ggtgcagata attgttccgg ttgcctgcta tgtatttttc
     2161 ggacttgttg tgatagtagg ttaaagtcag caccagagaa gcgttggcgg aatgggcgtt
     2221 gagcgctgtg tcttcattcg tcggggggcc gtccggagga gtctgttgtt tactgccgga
     2281 gagattttta cgatttgaaa ccttgtagga tgcctgaggt tgatctacaa gaaaagcgtc
     2341 agcgttcgga ttgaaataaa tctccggatc gtaagagaac agacaagtgc gtgctacatc
     2401 ctggccggag gtgtcgattt ctatctgaca gagttcggtg taaaaagaaa cgagtctggt
     2461 gtaagctgca tgatggaagt cttctatttc ctgaagggtt tcgggcaatg tctcatccgg
     2521 atggcatgcg cgtactatga ttttcacgcc catccctttg ggactgataa aggcgatgcg
     2581 ggtgtaattg catctcttga tgatagggag gatgcgtgcc aattcttctt tgctgaggtg
     2641 gtcgatgtct atcacgatgt gtcccagata tttgacgagg ttcactttgg tacgccttcc
     2701 tcggtagctg gcggagaagg cgattgccgg caattctttt ttcttctcat tggcagcctt
     2761 ttctccttgc tctgcaaaga tgcggcgtat ttcttcgact ttttcccggt aggtaaaact
     2821 gccgatagtg gacactattt cttcttcggt catctctgct attgcgtagt agaaaccttg
     2881 aaatatggtg aaatgtttca tttttatttt gattattgtt tgtcgatgca aaggaacttc
     2941 tttgcggaaa tgtgtaaagg aactttgtat aaaatggcaa taagttacta cggttcgccc
     3001 aaaaagtgta tgatagttgc cacttgtttc ggcgaaagga gacggttgcg tgcgcggtag
     3061 ccttcctgtt cgagttcgtg caggagaggg aggttgtaaa taatccaacg acgaagtatt
     3121 tgtaaagcaa ctttgaggca gacatgggga ttgtaaaggt gagccagttc cgctttggta
     3181 taggtgcgga taaggaaaga atcttctttg taattcatga tgttttcttc ttgttttatg
     3241 ctataaagtt acataaaatt ccttgttttt caaaggtttg acttcgtttt tattcgttgg
     3301 gaatcaagaa acttcgttgg ggaatatagc ttgtccggct atccttatct ttgtgctgtt
     3361 aacaagaagg ggatgcatcc tatgtattat aaactttaaa attattttat tatggcaatg
     3421 acagtatctt attcagtggt gccgcgcaag aatcctgcaa aaaagagcga accggcaaag
     3481 tattatgcac aggcgcaggc gtcgggtgag ctggactttg aagagttgtg cgaagcgatc
     3541 accagtcgtt ctacttgtac ggaaacggat gtacgtgcgg ctatttcggg tattctttac
     3601 gaagtgaaac gtgcgttgaa ggcaggaaga attgcgagac tgggcgattt gggcagtttg
     3661 cagataggac tcaacagtga aggtgcggca tcggtcaagg aattttccgg ttcaatgatt
     3721 aagggggcgc atcttatttt ccgccccggt aagacgctgg cggagttgat gaagattctg
     3781 agttatcagc aagtgcagac tcgtgcggtg gcgcaggcgg gtgcaggcga tggcggggga
     3841 gaagaccctg acaagaatcc ggattccggt ggtgatggct ccggtgatga agaggctccg
     3901 gaccctacgg tataattggc agacgggtca aggtaataac gaattagaat aacttccatt
     3961 aatattttga taagatgaaa gaaatagtaa accggatttt agatgtgatc atgtatctga
     4021 ttcctttctt cggaaagaga aagcgggaca gggtggtgag agaagtgcgc tatcatacta
     4081 cttgtaagga ggtgtgcaaa gtgaaaacga cggaaaggga aaaggaacat gagaaagatt
     4141 agtctgattg tgatccattg ttccgccacc cgtgtcgatt gcgactttac ggcaaaggat
     4201 gtggatacgg ctcaccgtta tcgtggcttt tcgtgctggg ggtatcatta ttatatatgc
     4261 aagtcgggcg agattgagcc gatgcgggat gaagatacgg tcggagctca tgcacgtggc
     4321 tataatgcga tcagcttagg tgtatgttat gagggcggtc ttgatgagaa tggaaaagct
     4381 gcggatacgc gtacaccccg tcagaaggag gcgctacatc gcttggtaca cgaattgttg
     4441 cagcgttatc cggaagctaa agtagtaggg catcgggatt taagtcccga caccaactat
     4501 aatgggatcg tagatccttg ggaacggatt aaagaatgtc cttgctttga ggtcattgga
     4561 gaattctcca ttaattaact accaccgtag tgaaatactc tttgaatacc tccgcagctt
     4621 tttcaagctg ttcgggggta ttttctttta cccctttcat cttgtattcc tgtcccatcg
     4681 cttcgtactt atgtacgccc agtgtatggt aaggcaatat ttccacccgt tggatcatct
     4741 tgtattttcc gagtgcttct cccagtgcgc gtatgtcttc ttcaaaatcg ctgtatccgg
     4801 gcactagcac gtagcgtagc cagaaaggtt tctcctgttc ttccagccag gcggccgtgc
     4861 ggatggtttg ctcgttgctt cttccggtga gcgtctgatg gcggttaggg ttgaattcct
     4921 ttatatccaa taacacaaga tcggtcagtc tgaataattc ttctacgtct tcgttccaaa
     4981 gtcctccgtt gctgtccaga cagacatgga tgcctttttc tttcagttcg cggaccagcg
     5041 ggacgagtgc tttcgcctga aacgtcggtt cgcctccgga gaaagtgatt ccccctcgtt
     5101 tcccgaagaa ggggcgctgg ctcattgcca tgcggacgat ttcttccggt ggggtaggcg
     5161 tgcctccctt tcctgctatc gtatccggat tggcgcaata gaggcagcgg aagttgcatc
     5221 cttgaagaaa aacgacgagc cgtaagcccg gcccgtcgaa tgttcccata ctttcgtatg
     5281 aatgtacgtt tatcatcata tagagtaata gattacatac gttcgtggaa gctacggctg
     5341 ataacttcca gttggtgttc gcggctcagc ttcacgaagt ttacggcata gccggaaacg
     5401 cggatagtca gctgcggata gttttccgga tgctccatgg catcgtacag catatcacgg
     5461 ttcagtacgt ttacgttcag gtggtgggca cctttggtga agtaaccgtc catcatcgtc
     5521 acgaggttct cgatacggtc ttcgtccgta gcacccagtg atttcggaac gatagagaag
     5581 gtgttgctga taccgtcctg tgagtcacgg taacgaagtt tcgctacaga actcagagaa
     5641 gcgatcgcac cattcttgtc gcgtccgtgc atcggattgg cacccggagc gaaggcaaca
     5701 cctttggcac gtccgtcggg agtagcaccg gtctttttgc cgtacatcac attggaagtg
     5761 atagtcagca aggagagggt aggacgggca ttcttgtaaa caggcaattt cttcaattct
     5821 tcgctgaaga agtataccag gtctacgcca aggtggtcta ccttgtcgtt gtcgttaccg
     5881 aagcaaggga attctccttc gatgtcgaag ccttctgtca gaccgatatc attgcggcgg
     5941 gcagttactt tcgcatattt gatggcagac agtgaatcga gggcgatgga aagtccggct
     6001 acaccgtaag ccaggttgat gcgcgggttc gtatctacaa gagccatctg ggccttctcg
     6061 tagtaatact tgtcgtgcat atagtggatg atgttcatcg cttcgttata tacgcgggcg
     6121 atttcggtca gcactttttt gtagttgtcc attacttctt cgaacttcag cgtgtcactg
     6181 gtcagtacgg ggatattctt caccatgact gtaccggtat tctcgcaacg tccgccgttg
     6241 atggcaagca acagggcttt ggccaggttg caacgggcgc cgaagaactg aatctgctta
     6301 cctatttcct ggtatgatac gcagcaggcg attccgtagt cgtcggactg acgtacttcg
     6361 cgcatcaggt cgtcattttc gtactggata gaagaagtgt cgatagaaac ctttgcacag
     6421 aattctttga atccttccgg aagttccggg ctccagagta cggtcaggtt cggttccggt
     6481 gaagggccga ggttgtacaa tgtctgcagg aaacggaagg aggtctttgt cactttggta
     6541 cgtccgtcgt tgagacgtcc gcccagagat tcggttaccc aggtcgggtc gcctgcaaag
     6601 atgtcgttgt atgattgcat acgcaggtgg cggaccatac gcagtttgat gacaaactgg
     6661 tcgatcagct cttgcgcgaa tgattcggtg atggttcctt tgctcagttc atattccaga
     6721 tagatatcga ggaaagaaga aacgttaccc agtgacatgg cggcaccgtc ttgttctttg
     6781 acggcggcaa ggtaagccat atatacccac tgtacggctt cttgtgccgt gtaagcggga
     6841 cggctcaggt cgagaccgta gtattcgccc atcactttca tgtctttcag tgccttgatc
     6901 tgttctgcca cttcttcgcg caggcggatg cgggcctctg tcatcggacc ggtgaggttg
     6961 tgcaaatctt ccttctttgc ttcgatcaga cggtcgatgc cgtaaagagc catacggcgg
     7021 tagtcaccga tgatgcgtcc gcgtgcataa ttgtcgggaa gtccggtaag gaatcccagc
     7081 gaacggaagg aacggatttc ttccgtatat acgtcgaata ctccgtcgtt gtgcgtcttg
     7141 cggtagtgag tgaaaatatc ttttacgcgg tcgtccactt ccacgccgtt ttcgtgacag
     7201 gctttgctga ctacattgat acctccgaaa ggcttgatgg cacgtttcag aagttcgtct
     7261 gtctgcaggc cgacgatcag ttcgttttcc ttgtcgatat atccggcctt gtgggaagtg
     7321 atggttgata cggtaacatt atctaatgag cggacaccgt tgttttctct ttcttctgcc
     7381 agtgcttcga ggcagcggtt ccatacggct ttggtacgtt ctgtaggtcc ttcgaggaat
     7441 gaagcatctc cgtaatacgg agtgatgtta tgacttacga aatctctgac gttgatttcg
     7501 ctgctccaaa gaccgtcttt aaagatcttg tttaattcca taaaatgata aaattagagg
     7561 ttgtagttat cctattcttt agagcgcaca aagttacaat catttttcat ataatcagca
     7621 taaatatgct ctattttatg cttttcaaca taaaatacct attaattgct atccttagga
     7681 aaagattaga ttaaattttt agtgaaaact cttgcaagtt taaaatatct tcgtaccttt
     7741 gcaccgcttt taacgaaaag cacttctgat aaggaagttt tggagaggtg gcagagtggt
     7801 cgattgcggc ggtcttgaaa accgttgtac cgcgaggtac ccggggttcg aatccctgtc
     7861 tctccgcaac aaacgctgaa aatcagcaga ttgcaaaaca aacacccagt tttacaccca
     7921 agaatgtaaa gtcggtgttt ttgttttatt taagataata caaccactac ataataaaag
     7981 agtagcgata ttaaaagaat ccgatgagaa aagactaata tttatctatc cattcagttt
     8041 gatttttcag gactttacat cgtcctgaaa gtatttgtta ttgtattcca acgtcaggag
     8101 tggattataa tacaagtttt ttgtgtggat agaatttcgt tttgcttaat gtacgaaagt
     8161 acttatctat aaacgcatga aatattagca caatgaatca ttggaaatca actttggccg
     8221 tgataggaat aggccaactc atatctattt taacaagtac gattgttggc ttctccatta
     8281 ttttttggat tagcaacgaa tttaaatccc cgacagcttt atctctggct attttagctg
     8341 gatttttacc acaatttgta ttaggcttgt ttgccggggt ctatgttgac agatggaatc
     8401 gaaagaaaac gatgttttat tcggacttgt tcatcgcgtt ctgtacccta tgtcttttta
     8461 ttgtgataac caagggttat aaagaccttt ctttttttta tctattgact gcttgtcgtt
     8521 caataggcag tacgtttcat gcacctgctt tacaggcaag catccctcta ctggttccca
     8581 agcaccatct tgtcagggta tcaggtttgt accattccat tcaatccttc agtgaggtga
     8641 tagctcccgt tgtaggggca agcctcgttg tttggcttcc catacagtat attctgctca
     8701 tagatgtgat cggagctgtt gctgcttgtc tgaccttact ttgtgtccag attccttctc
     8761 ttcaaaaaac gaaagttctt ccagatttca aaaaagaact gacggaatgt tggcatacct
     8821 tgcggcgtac aatgggcatt ttgcctttat tcgtatgctt tacgctggtg acttttgtcc
     8881 ttatgcctgt ttttacgtta tttcctttta tgacgcttct gcatttcaac ggaaacattt
     8941 tgcaaatggg agttgtggaa atgggttggg gctcaggggc attgttgggc ggtttagtac
     9001 ttgcctgtaa ggctttgaaa agcaagcaaa cattagtgat gcatacggct tatgtgatat
     9061 tgggattgta tctgattagc gccagttatt taccatcaag cgcatttata ggttttgttt
     9121 gcctaacatt tacaggaggc atagcctatt ccatttacca tgcgcttttc atcgctatta
     9181 ttcagcagaa cttggcttcg gacatgcttg gacggacttt ttctctcatc tttagtttga
     9241 gtacctttcc atcaatgctg ggtatcgtag cttcaggata ttgggtggaa gcatggggta
     9301 tcacatccgt ctttatgatc agcggatggg ttatctttct gattggagtg ggtgcaaatt
     9361 ttatttcttc aatcaagcag ttggataatt acgcatagta ttatttatta aagaattatt
     9421 atatgacaaa gaaagaacac actacgatta cagagttatt tcaagttttg gacttgttgg
     9481 aaagcctgga catgcagttt tggttggatg gaggctgggg agtggatgtc ttgtacggac
     9541 agcaaacccg cttgcataga gatattgaca ttgattttga tgccaattat acagaccaac
     9601 tccttgatct tttgcaggag agaggatatc aaattgaaac aaattggttg cccacccgtg
     9661 tggaactgta tagcaaagaa ttaggctata ttgatatcca tccttttgtc ttgaatgcgg
     9721 acggcacttc caaacaagcc gacttggatg gaggctggta tgaatttcaa ccggactatt
     9781 ttggaacagc agtctttgaa ggcagaagca tcccttgcat ttctgcaaaa gggcaacaag
     9841 tattccattc gggctacgat ttaagagaga aggatattca cgatttatct ataattaaac
     9901 aatgtataac aacaatgagc ctaacaatta gataagaaca agaaaatgac agaaaaacaa
     9961 attgtctggt atatcttact tacagaagta aagatagaca gtgacaccca gtctgtcaca
    10021 tccctgagtg tagctccatt ggcagtcttg ccggaattcc agcgtaaggg aattgggggg
    10081 ggatgttgat tcagtaagcc catcagaggg cagcactttt gggttacggc acagcagtcg
    10141 tattggggca taaagagtat tatcctcgat ttggctatcg caaggctatc gatttaggaa
    10201 ttgaatttcc tttcgaagtc tctcatgaat attgcatggt ggctgaatta atacctggag
    10261 ctactgagaa tgtgaaaggt atggtttgtt atccaactga ctttaaatag tttaacaagt
    10321 aaaattcatt atataactcg gactgggtat ttcaatttcc cagtccgtat tctgatagta
    10381 cttattcaat tggaagattg tgttgcttca agaatgaaag tttatcccaa taccctcttt
    10441 gaaagacgat tttgttatct tttacatgaa aaaatccgca tccacgaagt ccaagagagt
    10501 ctttccattc catgatagcc cattcgccat cttcaaaaat attttccacc atacaaacca
    10561 ttttagcagt ggcaaattca ttcacaaaca ttttgtagat tgattcttta cctattattg
    10621 gttcgtttgc gacttgatga tttactgcat tagtagcata cagctctgct atatgataag
    10681 catctgcttt gttaaagcaa tctatccatt tttccaaaac ttctttaggc ttcatttttt
    10741 ataaattctt aggattttga ttctgtaata aaaacaatct gtttggatgc atagatactt
    10801 gattttatta ataataggct attctatatt ctaaatcctc tggatttttg ctctctctgc
    10861 accgagttac gtagattctg ctgtaacttt tcccattgtt ccttaaacca ttgtactatg
    10921 ggttgtcggt ttatggtcag cataagctta ccactatcca tcggatgttt ctcaacccta
    10981 aaaatatcat tcttgatgtc aaatttccac ctgtgttctt cggaataaat tttgccacta
    11041 cattgtatgg attctttctt tgtcaagagg ttttctatca tgtctttggt aaacccgata
    11101 acagcgcata atttttccat tctcaacatc tctttgaaca tgggaaacca tttgtgggct
    11161 ttttcaagca aggtgctcaa tcgtgatatt tccttgtctt tggcttcaag ttcttgatta
    11221 tgtattcttt gaagattacg aatttgtctg ctatgctgtt cctgtatttg ttgtatctga
    11281 atttttaatt catcagtagc tttgtcccgt ttggtaattt cctgatgtag ctgctcgatg
    11341 tgatgttcca gttctttcag cttaccgctt ccgaaaagag aacctacacc gcttgctatg
    11401 gcggtagcag cattggtggc tgttttcttt agtttgtccg tgcgtatctc tgcttttacc
    11461 tgtttgagtt cctgttcggc aaggcttact tgttgttcct tgtgtcgctt ggtttcctct
    11521 atacgttgca gttcggcttt ctgcttctca atgatgaaat catttcgttc cagatgctct
    11581 ttacctgtga cagcttttgc ctgtccacgt tccatcagga gaatatcgga agcaagggtc
    11641 tgcatggttg ccatatcctc gtcattgagc tttcggctct ttccagtttc atggttcatc
    11701 cagtcgaata cgacatgagc atgataattt ggtttgaacc atctgttacc gacttggaag
    11761 ctctccttgt cttctgcttc cggctgaccg ttcagccaat gcccttcgtc tttatgcagg
    11821 aaaatctgta gcggagtgat gccccagcgt ctttggcact cttcaccgaa tttgcgtaca
    11881 tcagccagtg tggtgtccgg tctgataagc aatactcctt cacggatggg tgagcatccc
    11941 gccaccttga taatctttcc attctttccc ttgcgttccc tttccttttc ctgcatggca
    12001 cgtccggtct tttccttgac catttgcttg atattgtcat aatgagttcg cagttcggga
    12061 gtgccgaagt cgggatttat ccactgttcg ttatcggtgg aaagttcggg aacgacatag
    12121 attctggact ccccgatatt acgcatatac tcggcagtcc ttcggttgtg tgcctcgctc
    12181 gatgcgatgt tgcaaggctt gatatgtatg cttgattttg ttgccatagc ttctttcctt
    12241 tgtttacaat tgatttactt tgctcgcttt cgcagagggg ttcttagggg taacccataa
    12301 gcggagattg caaagagagg gtcactcttt gctcggggtt ctcaggggtg aaacgccctg
    12361 agtgggtcat tagggcaaag ccctaatccc ctcgggagag cccacaacta cgcaagcgaa
    12421 gcgtgtagtt atagtgggct ataaccggaa gcctttcggt ttcttggata gcgtatcatt
    12481 cctcttttcg acagattgcg cttgctcttt cctatcggct attcgtttct gtaaatattc
    12541 gttcagatct ttacatccac tgtagatttg cgaggcgtca cgtatatacc gggtagcatc
    12601 atactccttt cggatttgct gtattgcttc cattcctgca cggtcattgt caaagaaaca
    12661 gtggatgcgc tcatagcttc ccaacggata gagtgccttg ggaacattgg ctacggaatt
    12721 aagaactatg taatcctgtc tgtcgaagtc gggtgattgc ggacagcttt ccagccttaa
    12781 agtaagaaag gaaaggtaat ccataaatcc ctcaaaaacg taacatgtac tccttggttt
    12841 tcctgactgt ctgatatggg atatttcttt tggtgcgata catcccttga aatatcggtt
    12901 gcgaatttca tatccgcctg atatgttcgg aaaggcaatg gcgaaatacc gtttgccgtt
    12961 gtgggtgaaa cgggcttcct tacattctct tttcgccagt gccgtgttta tccctctttc
    13021 ctgtaggtag gcaagcaggg caggagaagc cagcagcaca atgtccaatt gctgaaaact
    13081 cggttcggaa aatgattgct tgccaaaaga gaaagacacg ggacgtatgt gtggtatctg
    13141 ttcttcgatt ttctgtagaa gataaggcac atagtcggaa cagtagagtt cctgtgccag
    13201 tgcgatgata tttccacctt tgccgattgc gaaatcatac cattggttgc gctcggtatt
    13261 tactttgaac gagggttctg tctcttcccg taacggggat ttgtaccata ggttaatacc
    13321 ttgctgcttg acgggagaat atcccaaact gtacagaaaa tccgctatcc tgatttgttt
    13381 tgctgtctgt atatccataa taagatgagt gtttgaataa tggttggaat atttatttct
    13441 cttttcgccc gtactttttt atgaagtacg gtctgtataa tcacttcact ttatcttcgt
    13501 atatatagga tacggtaata aagtgaagcg cttttctatt ccctacaacc gcttcgcttt
    13561 attcttaata tatagacctg ccgaataaag tgaagtgatt acaggttata cggtctaata
    13621 gtgaaagtcc ggcttgaacg tgtatttcct gccgttctcc tgtactatca tccgtttgtt
    13681 ccggagcatg gtgataagtg ataccgcttt ttgatggttc agttttacac ctaccgacat
    13741 atatgacttg attaaggagg tttccagatc cttgtagccg tattcctctt tcagtccgaa
    13801 agccgcttcc agtgctatgc ggtgctgctg ttcgctaata tgtctgtaag ggtcaaactt
    13861 ttcctcttcc ggtcttccgg gtttcttcgc ttcgggtctg tacccctcta tgagttcagg
    13921 caatgcattg tcgttgatac ggaaagcgaa aggctcgaaa tccattgcac ggatgtgcat
    13981 ggctgaaaca ttgcttatat ccccgttgct cttgtccttt tccaccagca gaacggtttc
    14041 cgccttgttg ttcagctccg taccgatatg ccctcttgcg ttttcatcgc ctttgttctg
    14101 gtggagtatc gtatggatgt gtatctgcct gtcatccgtc cactgcatca gtttggatat
    14161 aatgcgtgtc gattctcccg gactgttgat gtcatatacc atatcacgga tgccgtctat
    14221 gattacaagc cctatgtccg gtgtattata gatagcctgt tcgacaatcc tgatacgctg
    14281 ttcgggcgtg tatttcctca aagcgagaaa ctccagatgt tcattgtccc tgtcatcagg
    14341 aagaccagca agccgtaaaa tacgtttcat gactttcaga cagtgataat ggctttgttc
    14401 cgtgtccaca taaagaatct tccttttttc ttccggtagt tccgcaacat accgcagtac
    14461 cgtaccgttt ttcaatgcgg cggctacgat agccgataca ttgaaagtct ttttactctt
    14521 ggctttgccg atggatgcac tgaaattgcc cagtgtacca atgaccgaac cttgcacttt
    14581 tagaatctca ggtgcttttt cgtagatttt cgacagactc aggcgtgaag cttgccaaag
    14641 gattattgcc tgttctgccg aaatctcctt tatttctttc atatagtcca taagcatacc
    14701 tcccattatt tccgtcctcc tgttttcttc ccggcaagct caagagccaa ttccgcatct
    14761 acgataatct tgcgccctat ctgggtaatc gccttgtcta tcttaccgct tttctttatg
    14821 cggttggcag tgggcagact gcacccgaac agtttggcta taccgagtat tccgtacaca
    14881 tacttctttt ccgtgtctgt aacgggttgc ggcaatgctt cggcctgacc tgaagcgtgc
    14941 ttactcagga atatgaattc ttcgcctgtc atctgccaga cgggttttga taataattct
    15001 tggatatttg tcatcgtcca atctatttag tcgttaaaca atcagccctg cgcactggct
    15061 gttatttctg ttctcgaacg atgcaaaatt aggtagggtt atgagtggta aggatgggga
    15121 cggtacaaac tgaatatcat tgtatcttat tgaatatcag aaaataaaaa taccactcaa
    15181 aaattatttt gagtggtaaa agtggaactt tcgtaaagta tcaggatata ttacggatta
    15241 tctgaatata tgttccattt ccttggcgaa attttggttg ctgtcactgg ggaaatctga
    15301 aacaggctcc ttgtacttgg atttgtagta gctgtcgtca atatccagca gtttcagtat
    15361 tctgtctttc catttgtccc tgtcctgttt ggagagtttc tcgctcatca ggaatatcag
    15421 atagcataca cgtattttct ctctcggttt tattttcagc ttacagttgc aggggtgaag
    15481 attcatattg gcatagaaat ccagtgcgga aatttcttcg aactgttctc ctatgcacac
    15541 ctcatgaatg agcgaaagta atttcatgct gaaatattcc tgttgttctt ctgtcgtttc
    15601 ctgctgactg attggctcgc ttgatttatt ctcttgcttt ccgtcaggaa tgtatttctt
    15661 caatatatcc agaaaaaggc agctttgacg gtatatgtcc gcacaacagt tcttcatgta
    15721 ttggaatgcc tctgttcttg cagccttttg ctgatcatag agtttgttca gtttggcttt
    15781 ttccctgtca tattcagcct tgcagcgttc atattctttc tctgcctgtt tttcctcttc
    15841 ggctgtatgc tccctgtaac caatggaatc atacctgttg ttggcttcat tcagcggctt
    15901 gctcagactt cttgtaacat ccagctgggc ttcaatttcc tgagaatacc tttccatgtg
    15961 ctgatagcaa gcacgttcta tggctctgtc acttaacggg cgtatctcat aagcctgtat
    16021 gctcttttct atttcagttt tcaggctgtt gagtatcaag gtgtattgct ctttttgctt
    16081 gtcaagcacc agttcaagga tagcggcttc aaaggatttc atgtcattat actcctgata
    16141 gaaatccgat atgaatttct gcctgtcaaa agaaaaagcg taattatcta tatagtctct
    16201 gtatattctg ttgagttctc catattgggg aatcatcgtc tgtatctttc ctgccatata
    16261 ctttatatta tgggttcttg tccttgtcaa ggaataaggt cagttcttct tccacttctt
    16321 ctatactcgg tagggcagat ttcagatttt cgggtactgc cttgctcaat tgatagtcgc
    16381 tgatacctat cggctggtca tatccagcca aggcatattg tgccacgacc tcatccttac
    16441 ccctgcacag caaaagaccg atggtcttgt tatcattttc tcccctcagt ttatcatcta
    16501 caacattgat atagaaattt aactgccctg catattccgg tttgaatggc gttgctttca
    16561 attccacgac aacataggca tggagcttga tattatatag gatcaggtcg gcgaaaaagt
    16621 cactgtcccc aatctggaaa tgtttttgtc tggcaacaaa agcaaagccg ttacccattt
    16681 ccagcaagta acgggttaca tgctttacca actgttcttc tatatccctt tcgtcagcct
    16741 tttcctttgc tcctgccaag tcaaagatat acgggtcttt taacagataa ttggcaagat
    16801 cgctttgagg tgccggaagt gtggcagtga agttgtttac cttgttactc ttgatttgtc
    16861 tgtcatacag attactttca atctgcattt tcagcacatt actgctccaa cccatttcta
    16921 cagattgttt catataccaa taccttacgc ccaatggtag cggattattg agtatgacca
    16981 tatggcttgc ccaatttatt cttgcaatcg gtgacgccaa gaataaatct tctatatcct
    17041 ctatttttat tttatagatg gttgctactg tttttgctac attctgaaat tgcgcaggaa
    17101 cctcctgcgt aatttctaaa gattgattat cagctgattg tatttgcgca gtaagctcct
    17161 gcgtaaattg tccgctattg agcttaagga cttcattagt aatgttttga atatttggga
    17221 ccgacagtat tgaatctgct tcaataaaac tacgaagtac atttaacgga tataaacggg
    17281 caaactggca catataagta agattacgtt ccgaatatcc cttcttttca ggataattga
    17341 atctgattgc ctgtgccaat tttttgataa ttttaccacc ccacccatgt aggtgttggt
    17401 ggtacagtat ataattcccc attttccagt aatggaacaa catctgggca ttggctgcgg
    17461 taatgagtcg gacttgtgcc tgttctattt ccgaaccgac agcatggaca aaggcatcaa
    17521 aatgaccttt ctttatatta t
//
