LOCUS       c00013_gnlPro..        17421 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MGJAJOAL_13.
ACCESSION   c00013_gnlPro..
VERSION     c00013_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 13:47:19
            Original ID  :: gnl|Prokka|MGJAJOAL_13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1847
            Orig. end    :: 19268
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17421
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[11847:14818]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12971
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17421
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17421
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             1285..2304
                     /locus_tag="ctg13_4"
                     /transl_table=11
                     /translation="MAGKIQTMIPQYGELNRIYRDYIDNYAFSFDRQKFISDFYQEYND
                     MKSFEAAILELVLDKQKEQYTLILNSLKTEIEKSIQAYEIRPLSDRAIERACYQHMERY
                     SQEIEAQLDVTRSLSKPLNEANNRYDSIGYREHTAEEEKQAEKEYERCKAEYDREKAKL
                     NKLYDQQKAARTEAFQYMKNCCADIYRQSCLFLDILKKYIPDGKQENKSSEPISQQETT
                     EEQQEYFSMKLLSLIHEVCIGEQFEEISALDFYANMNLHPCNCKLKIKPREKIRVCYLI
                     FLMSEKLSKQDRDKWKDRILKLLDIDDSYYKSKYKEPVSDFPSDSNQNFAKEMEHIFR"
     CDS             2528..2836
                     /locus_tag="ctg13_5"
                     /transl_table=11
                     /translation="MTNIQELLSKPVWQMTGEEFIFLSKHASGQAEALPQPVTDTEKKY
                     VYGILGIAKLFGCSLPTANRIKKSGKIDKAITQIGRKIIVDAELALELAGKKTGGRK"
     CDS             2845..3927
                     /locus_tag="ctg13_6"
                     /transl_table=11
                     /translation="MLMDYMKEIKEISAEQAIILWQASRLSLSKIYEKAPEILKVQGSV
                     IGTLGNFSASIGKAKSKKTFNVSAIVAAALKNGTVLRYVAELPEEKRKILYVDTEQSHY
                     HCLKVMKRILRLAGLPDDRDNEHLEFLALRKYTPEQRIRIVEQAIYNTPDIGLVIIDGI
                     RDMVYDINSPGESTRIISKLMQWTDDRQIHIHTILHQNKGDENARGHIGTELNNKAETV
                     LLVEKDKSNGDISNVSAMHIRAMDFEPFAFRINDNALPELIEGYRPEAKKPGRPEEEKF
                     DPYRHISEQQHRIALEAAFGLKEEYGYKDLETSLIKSYMSVGVKLNHQKAVSLITMLRN
                     KRMIVQENGRKYTFKPDFHY"
     CDS             4144..5103
                     /locus_tag="ctg13_7"
                     /transl_table=11
                     /translation="MDIQTAKQIRIADFLYSLGYSPVKQQGINLWYKSPLREETEPSFK
                     VNTERNQWYDFAIGKGGNIIALAQELYCSDYVPYLLQKIEEQIPHIRPVSFSFGKQSFS
                     EPSFQQLDIVLLASPALLAYLQERGINTALAKRECKEARFTHNGKRYFAIAFPNISGGY
                     EIRNRYFKGCIAPKEISHIRQSGKPRSTCYVFEGFMDYLSFLTLRLESCPQSPDFDRQD
                     YIVLNSVANVPKALYPLGSYERIHCFFDNDRAGMEAIQQIRKEYDATRYIRDASQIYSG
                     CKDLNEYLQKRIADRKEQAQSVEKRNDTLSKKPKGFRL"
     CDS             5315..6718
                     /locus_tag="ctg13_8"
                     /transl_table=11
                     /translation="MATKSSIHIKPCNIASSEAHNRRTAEYMRNIGESRIYVVPELSTD
                     NEQWINPDFGTPELRTHYDNIKQMVKEKTGRAMQEKERERKGKNGKIIKVAGCSPIREG
                     VLLIRPDTTLADVRKFGEECQRRWGITPLQIFLHKDEGHWLNGQPEAEDKESFQVGNRW
                     FKPNYHAHVVFDWMNHETGKSRKLNDEDMATMQTLASDILLMERGQAKAVTGKEHLERN
                     DFIIEKQKAELQRIEETKRHKEQQVSLAEQELKQVKAEIRTDKLKKTATNAATAIASGV
                     GSLFGSGKLKELEHHIEQLHQEITKRDKATDELKIQIQQIQEQHSRQIRNLQRIHNQEL
                     EAKDKEISRLSTLLEKAHKWFPMFKEMLRMEKLCAVIGFTKDMIENLLTKKESIQCSGK
                     IYSEEHRWKFDIKNDIFRVEKHPMDSGKLMLTINRQPIVQWFKEQWEKLQQNLRNSVQR
                     EQKSRGFRI"
     CDS             6807..7160
                     /locus_tag="ctg13_9"
                     /transl_table=11
                     /translation="MKPKEVLEKWIDCFNKADAYHIAELYATNAVNHQVANEPIIGKES
                     IYKMFVNEFATAKMVCMVENIFEDGEWAIMEWKDSLGLRGCGFFHVKDNKIVFQRGYWD
                     KLSFLKQHNLPIE"
     CDS             complement(7453..7596)
                     /locus_tag="ctg13_10"
                     /transl_table=11
                     /translation="MTEKQIVWYILLTEVKIDSDTQSVTSLSVAPLAVLPEFQRKGIGG
                     GC"
     CDS             complement(7607..8119)
                     /locus_tag="ctg13_11"
                     /transl_table=11
                     /translation="MTKKEHTTITELFQVLDLLESLDMQFWLDGGWGVDVLYGQQTRLH
                     RDIDIDFDANYTDQLLDLLQERGYQIETNWLPTRVELYSKELGYIDIHPFVLNADGTSK
                     QADLDGGWYEFQPDYFGTAVFEGRSIPCISAKGQQVFHSGYDLREKDIHDLSIIKQCIT
                     TMSLTIR"
     CDS             complement(8144..9349)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 94.2; E-value: 2.6e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg13_12"
                     /sec_met_domain="MFS_1 (E-value: 8.7e-30, bitscore: 94.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHWKSTLAVIGIGQLISILTSTIVGFSIIFWISNEFKSPTALSL
                     AILAGFLPQFVLGLFAGVYVDRWNRKKTMFYSDLFIAFCTLCLFIVITKGYKDLSFFYL
                     LTACRSIGSTFHAPALQASIPLLVPKHHLVRVSGLYHSIQSFSEVIAPVVGASLVVWLP
                     IQYILLIDVIGAVAACLTLLCVQIPSLQKTKVLPDFKKELTECWHTLRRTMGILPLFVC
                     FTLVTFVLMPVFTLFPFMTLLHFNGNILQMGVVEMGWGSGALLGGLVLACKALKSKQTL
                     VMHTAYVILGLYLISASYLPSSAFIGFVCLTFTGGIAYSIYHALFIAIIQQNLASDMLG
                     RTFSLIFSLSTFPSMLGIVASGYWVEAWGITSVFMISGWVIFLIGVGANFISSIKQLDN
                     YA"
     CDS             10001..12229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_13"
                     /sec_met_domain="Gly_radical (E-value: 1.3e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             12243..12971
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.5;
                     E-value: 1.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_14"
                     /sec_met_domain="Radical_SAM (E-value: 3.9e-29, bitscore:
                     92.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(12964..13413)
                     /locus_tag="ctg13_15"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYICK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(13400..13567)
                     /locus_tag="ctg13_16"
                     /transl_table=11
                     /translation="MKEIVNRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(13627..14130)
                     /locus_tag="ctg13_17"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             14324..14554
                     /locus_tag="ctg13_18"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             14641..16755
                     /locus_tag="ctg13_19"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     NYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIAGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETVSLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(16825..17130)
                     /locus_tag="ctg13_20"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(17111..17419)
                     /locus_tag="ctg13_21"
                     /transl_table=11
                     /translation="TEIYTCIVSAASDCIRDRILYVLMLLQTQDRIPLKFMRLIEEGLY
                     ELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIDKAKILRKEYYGSKNK"
ORIGIN
        1 ataatataaa gaaaggtcat tttgatgcct ttgtccatgc tgtcggttcg gaaatagaac
       61 aggcacaagt ccgactcatt accgcagcca atgcccagat gttgttccat tactggaaaa
      121 tggggaatta tatactgtac caccaacacc tacatgggtg gggtggtaaa attatcaaaa
      181 aattggcaca ggcaatcaga ttcaattatc ctgaaaagaa gggatattcg gaacgtaatc
      241 ttacttatat gtgccagttt gcccgtttat atccgttaaa tgtacttcgt agttttattg
      301 aagcagattc aatactgtcg gtcccaaata ttcaaaacat tactaatgaa gtccttaagc
      361 tcaatagcgg acaatttacg caggagctta ctgcgcaaat acaatcagct gataatcaat
      421 ctttagaaat tacgcaggag gttcctgcgc aatttcagaa tgtagcaaaa acagtagcaa
      481 ccatctataa aataaaaata gaggatatag aagatttatt cttggcgtca ccgattgcaa
      541 gaataaattg ggcaagccat atggtcatac tcaataatcc gctaccattg ggcgtaaggt
      601 attggtatat gaaacaatct gtagaaatgg gttggagcag taatgtgctg aaaatgcaga
      661 ttgaaagtaa tctgtatgac agacaaatca agagtaacaa ggtaaacaac ttcactgcca
      721 cacttccggc acctcaaagc gatcttgcca attatctgtt aaaagacccg tatatctttg
      781 acttggcagg agcaaaggaa aaggctgacg aaagggatat agaagaacag ttggtaaagc
      841 atgtaacccg ttacttgctg gaaatgggta acggctttgc ttttgttgcc agacaaaaac
      901 atttccagat tggggacagt gactttttcg ccgacctgat cctatataat atcaagctcc
      961 atgcctatgt tgtcgtggaa ttgaaagcaa cgccattcaa accggaatat gcagggcagt
     1021 taaatttcta tatcaatgtt gtagatgata aactgagggg agaaaatgat aacaagacca
     1081 tcggtctttt gctgtgcagg ggtaaggatg aggtcgtggc acaatatgcc ttggctggat
     1141 atgaccagcc gataggtatc agcgactatc aattgagcaa ggcagtaccc gaaaatctga
     1201 aatctgccct accgagtata gaagaagtgg aagaagaact gaccttattc cttgacaagg
     1261 acaagaaccc ataatataaa gtatatggca ggaaagatac agacgatgat tccccaatat
     1321 ggagaactca acagaatata cagagactat atagataatt acgctttttc ttttgacagg
     1381 cagaaattca tatcggattt ctatcaggag tataatgaca tgaaatcctt tgaagccgct
     1441 atccttgaac tggtgcttga caagcaaaaa gagcaataca ccttgatact caacagcctg
     1501 aaaactgaaa tagaaaagag catacaggct tatgagatac gcccgttaag tgacagagcc
     1561 atagaacgtg cttgctatca gcacatggaa aggtattctc aggaaattga agcccagctg
     1621 gatgttacaa gaagtctgag caagccgctg aatgaagcca acaacaggta tgattccatt
     1681 ggttacaggg agcatacagc cgaagaggaa aaacaggcag agaaagaata tgaacgctgc
     1741 aaggctgaat atgacaggga aaaagccaaa ctgaacaaac tctatgatca gcaaaaggct
     1801 gcaagaacag aggcattcca atacatgaag aactgttgtg cggacatata ccgtcaaagc
     1861 tgcctttttc tggatatatt gaagaaatac attcctgacg gaaagcaaga gaataaatca
     1921 agcgagccaa tcagtcagca ggaaacgaca gaagaacaac aggaatattt cagcatgaaa
     1981 ttactttcgc tcattcatga ggtgtgcata ggagaacagt tcgaagaaat ttccgcactg
     2041 gatttctatg ccaatatgaa tcttcacccc tgcaactgta agctgaaaat aaaaccgaga
     2101 gagaaaatac gtgtatgcta tctgatattc ctgatgagcg agaaactctc caaacaggac
     2161 agggacaaat ggaaagacag aatactgaaa ctgctggata ttgacgacag ctactacaaa
     2221 tccaagtaca aggagcctgt ttcagatttc cccagtgaca gcaaccaaaa tttcgccaag
     2281 gaaatggaac atatattcag ataatccgta atatatcctg atactttacg aaagttccac
     2341 ttttaccact caaaataatt tttgagtggt atttttattt tctgatattc aataagatac
     2401 aatgatattc agtttgtacc gtccccatcc ttaccactca taaccctacc taattttgca
     2461 tcgttcgaga acagaaataa cagccagtgc gcagggctga ttgtttaacg actaaataga
     2521 ttggacgatg acaaatatcc aagaattatt atcaaaaccc gtctggcaga tgacaggcga
     2581 agaattcata ttcctgagta agcacgcttc aggtcaggcc gaagcattgc cgcaacccgt
     2641 tacagacacg gaaaagaagt atgtgtacgg aatactcggt atagccaaac tgttcgggtg
     2701 cagtctgccc actgccaacc gcataaagaa aagcggtaag atagacaagg cgattaccca
     2761 gatagggcgc aagattatcg tagatgcgga attggctctt gagcttgccg ggaagaaaac
     2821 aggaggacgg aaataatggg aggtatgctt atggactata tgaaagaaat aaaggagatt
     2881 tcggcagaac aggcaataat cctttggcaa gcttcacgcc tgagtctgtc gaaaatctac
     2941 gaaaaagcac ctgagattct aaaagtgcaa ggttcggtca ttggtacact gggcaatttc
     3001 agtgcatcca tcggcaaagc caagagtaaa aagactttca atgtatcggc tatcgtagcc
     3061 gccgcattga aaaacggtac ggtactgcgg tatgttgcgg aactaccgga agaaaaaagg
     3121 aagattcttt atgtggacac ggaacaaagc cattatcact gtctgaaagt catgaaacgt
     3181 attttacggc ttgctggtct tcctgatgac agggacaatg aacatctgga gtttctcgct
     3241 ttgaggaaat acacgcccga acagcgtatc aggattgtcg aacaggctat ctataataca
     3301 ccggacatag ggcttgtaat catagacggc atccgtgata tggtatatga catcaacagt
     3361 ccgggagaat cgacacgcat tatatccaaa ctgatgcagt ggacggatga caggcagata
     3421 cacatccata cgatactcca ccagaacaaa ggcgatgaaa acgcaagagg gcatatcggt
     3481 acggagctga acaacaaggc ggaaaccgtt ctgctggtgg aaaaggacaa gagcaacggg
     3541 gatataagca atgtttcagc catgcacatc cgtgcaatgg atttcgagcc tttcgctttc
     3601 cgtatcaacg acaatgcatt gcctgaactc atagaggggt acagacccga agcgaagaaa
     3661 cccggaagac cggaagagga aaagtttgac ccttacagac atattagcga acagcagcac
     3721 cgcatagcac tggaagcggc tttcggactg aaagaggaat acggctacaa ggatctggaa
     3781 acctccttaa tcaagtcata tatgtcggta ggtgtaaaac tgaaccatca aaaagcggta
     3841 tcacttatca ccatgctccg gaacaaacgg atgatagtac aggagaacgg caggaaatac
     3901 acgttcaagc cggactttca ctattagacc gtataacctg taatcacttc actttattcg
     3961 gcaggtctat atattaagaa taaagcgaag cggttgtagg gaatagaaaa gcgcttcact
     4021 ttattaccgt atcctatata tacgaagata aagtgaagtg attatacaga ccgtacttca
     4081 taaaaaagta cgggcgaaaa gagaaataaa tattccaacc attattcaaa cactcatctt
     4141 attatggata tacagacagc aaaacaaatc aggatagcgg attttctgta cagtttggga
     4201 tattctcccg tcaagcagca aggtattaac ctatggtaca aatccccgtt acgggaagag
     4261 acagaaccct cgttcaaagt aaataccgag cgcaaccaat ggtatgattt cgcaatcggc
     4321 aaaggtggaa atatcatcgc actggcacag gaactctact gttccgacta tgtgccttat
     4381 cttctacaga aaatcgaaga acagatacca cacatacgtc ccgtgtcttt ctcttttggc
     4441 aagcaatcat tttccgaacc gagttttcag caattggaca ttgtgctgct ggcttctcct
     4501 gccctgcttg cctacctaca ggaaagaggg ataaacacgg cactggcgaa aagagaatgt
     4561 aaggaagccc gtttcaccca caacggcaaa cggtatttcg ccattgcctt tccgaacata
     4621 tcaggcggat atgaaattcg caaccgatat ttcaagggat gtatcgcacc aaaagaaata
     4681 tcccatatca gacagtcagg aaaaccaagg agtacatgtt acgtttttga gggatttatg
     4741 gattaccttt cctttcttac tttaaggctg gaaagctgtc cgcaatcacc cgacttcgac
     4801 agacaggatt acatagttct taattccgta gccaatgttc ccaaggcact ctatccgttg
     4861 ggaagctatg agcgcatcca ctgtttcttt gacaatgacc gtgcaggaat ggaagcaata
     4921 cagcaaatcc gaaaggagta tgatgctacc cggtatatac gtgacgcctc gcaaatctac
     4981 agtggatgta aagatctgaa cgaatattta cagaaacgaa tagccgatag gaaagagcaa
     5041 gcgcaatctg tcgaaaagag gaatgatacg ctatccaaga aaccgaaagg cttccggtta
     5101 tagcccacta taactacacg cttcgcttgc gtagttgtgg gctctcccga ggggattagg
     5161 gctttgccct aatgacccac tcagggcgtt tcacccctga gaaccccgag caaagagtga
     5221 ccctctcttt gcaatctccg cttatgggtt acccctaaga acccctctgc gaaagcgagc
     5281 aaagtaaatc aattgtaaac aaaggaaaga agctatggca acaaaatcaa gcatacatat
     5341 caagccttgc aacatcgcat cgagcgaggc acacaaccga aggactgccg agtatatgcg
     5401 taatatcggg gagtccagaa tctatgtcgt tcccgaactt tccaccgata acgaacagtg
     5461 gataaatccc gacttcggca ctcccgaact gcgaactcat tatgacaata tcaagcaaat
     5521 ggtcaaggaa aagaccggac gtgccatgca ggaaaaggaa agggaacgca agggaaagaa
     5581 tggaaagatt atcaaggtgg cgggatgctc acccatccgt gaaggagtat tgcttatcag
     5641 accggacacc acactggctg atgtacgcaa attcggtgaa gagtgccaaa gacgctgggg
     5701 catcactccg ctacagattt tcctgcataa agacgaaggg cattggctga acggtcagcc
     5761 ggaagcagaa gacaaggaga gcttccaagt cggtaacaga tggttcaaac caaattatca
     5821 tgctcatgtc gtattcgact ggatgaacca tgaaactgga aagagccgaa agctcaatga
     5881 cgaggatatg gcaaccatgc agacccttgc ttccgatatt ctcctgatgg aacgtggaca
     5941 ggcaaaagct gtcacaggta aagagcatct ggaacgaaat gatttcatca ttgagaagca
     6001 gaaagccgaa ctgcaacgta tagaggaaac caagcgacac aaggaacaac aagtaagcct
     6061 tgccgaacag gaactcaaac aggtaaaagc agagatacgc acggacaaac taaagaaaac
     6121 agccaccaat gctgctaccg ccatagcaag cggtgtaggt tctcttttcg gaagcggtaa
     6181 gctgaaagaa ctggaacatc acatcgagca gctacatcag gaaattacca aacgggacaa
     6241 agctactgat gaattaaaaa ttcagataca acaaatacag gaacagcata gcagacaaat
     6301 tcgtaatctt caaagaatac ataatcaaga acttgaagcc aaagacaagg aaatatcacg
     6361 attgagcacc ttgcttgaaa aagcccacaa atggtttccc atgttcaaag agatgttgag
     6421 aatggaaaaa ttatgcgctg ttatcgggtt taccaaagac atgatagaaa acctcttgac
     6481 aaagaaagaa tccatacaat gtagtggcaa aatttattcc gaagaacaca ggtggaaatt
     6541 tgacatcaag aatgatattt ttagggttga gaaacatccg atggatagtg gtaagcttat
     6601 gctgaccata aaccgacaac ccatagtaca atggtttaag gaacaatggg aaaagttaca
     6661 gcagaatcta cgtaactcgg tgcagagaga gcaaaaatcc agaggattta gaatatagaa
     6721 tagcctatta ttaataaaat caagtatcta tgcatccaaa cagattgttt ttattacaga
     6781 atcaaaatcc taagaattta taaaaaatga agcctaaaga agttttggaa aaatggatag
     6841 attgctttaa caaagcagat gcttatcata tagcagagct gtatgctact aatgcagtaa
     6901 atcatcaagt cgcaaacgaa ccaataatag gtaaagaatc aatctacaaa atgtttgtga
     6961 atgaatttgc cactgctaaa atggtttgta tggtggaaaa tatttttgaa gatggcgaat
     7021 gggctatcat ggaatggaaa gactctcttg gacttcgtgg atgcggattt tttcatgtaa
     7081 aagataacaa aatcgtcttt caaagagggt attgggataa actttcattc ttgaagcaac
     7141 acaatcttcc aattgaataa gtactatcag aatacggact gggaaattga aatacccagt
     7201 ccgagttata taatgaattt tacttgttaa actatttaaa gtcagttgga taacaaacca
     7261 tacctttcac attctcagta gctccaggta ttaattcagc caccatgcaa tattcatgag
     7321 agacttcgaa aggaaattca attcctaaat cgatagcctt gcgatagcca aatcgaggat
     7381 aatactcttt atgccccaat acgactgctg tgccgtaacc caaaagtgct gccctctgat
     7441 gggcttactg aatcaacatc cccccccaat tcccttacgc tggaattccg gcaagactgc
     7501 caatggagct acactcaggg atgtgacaga ctgggtgtca ctgtctatct ttacttctgt
     7561 aagtaagata taccagacaa tttgtttttc tgtcattttc ttgttcttat ctaattgtta
     7621 ggctcattgt tgttatacat tgtttaatta tagataaatc gtgaatatcc ttctctctta
     7681 aatcgtagcc cgaatggaat acttgttgcc cttttgcaga aatgcaaggg atgcttctgc
     7741 cttcaaagac tgctgttcca aaatagtccg gttgaaattc ataccagcct ccatccaagt
     7801 cggcttgttt ggaagtgccg tccgcattca agacaaaagg atggatatca atatagccta
     7861 attctttgct atacagttcc acacgggtgg gcaaccaatt tgtttcaatt tgatatcctc
     7921 tctcctgcaa aagatcaagg agttggtctg tataattggc atcaaaatca atgtcaatat
     7981 ctctatgcaa gcgggtttgc tgtccgtaca agacatccac tccccagcct ccatccaacc
     8041 aaaactgcat gtccaggctt tccaacaagt ccaaaacttg aaataactct gtaatcgtag
     8101 tgtgttcttt ctttgtcata taataattct ttaataaata atactatgcg taattatcca
     8161 actgcttgat tgaagaaata aaatttgcac ccactccaat cagaaagata acccatccgc
     8221 tgatcataaa gacggatgtg ataccccatg cttccaccca atatcctgaa gctacgatac
     8281 ccagcattga tggaaaggta ctcaaactaa agatgagaga aaaagtccgt ccaagcatgt
     8341 ccgaagccaa gttctgctga ataatagcga tgaaaagcgc atggtaaatg gaataggcta
     8401 tgcctcctgt aaatgttagg caaacaaaac ctataaatgc gcttgatggt aaataactgg
     8461 cgctaatcag atacaatccc aatatcacat aagccgtatg catcactaat gtttgcttgc
     8521 ttttcaaagc cttacaggca agtactaaac cgcccaacaa tgcccctgag ccccaaccca
     8581 tttccacaac tcccatttgc aaaatgtttc cgttgaaatg cagaagcgtc ataaaaggaa
     8641 ataacgtaaa aacaggcata aggacaaaag tcaccagcgt aaagcatacg aataaaggca
     8701 aaatgcccat tgtacgccgc aaggtatgcc aacattccgt cagttctttt ttgaaatctg
     8761 gaagaacttt cgttttttga agagaaggaa tctggacaca aagtaaggtc agacaagcag
     8821 caacagctcc gatcacatct atgagcagaa tatactgtat gggaagccaa acaacgaggc
     8881 ttgcccctac aacgggagct atcacctcac tgaaggattg aatggaatgg tacaaacctg
     8941 ataccctgac aagatggtgc ttgggaacca gtagagggat gcttgcctgt aaagcaggtg
     9001 catgaaacgt actgcctatt gaacgacaag cagtcaatag ataaaaaaaa gaaaggtctt
     9061 tataaccctt ggttatcaca ataaaaagac atagggtaca gaacgcgatg aacaagtccg
     9121 aataaaacat cgttttcttt cgattccatc tgtcaacata gaccccggca aacaagccta
     9181 atacaaattg tggtaaaaat ccagctaaaa tagccagaga taaagctgtc ggggatttaa
     9241 attcgttgct aatccaaaaa ataatggaga agccaacaat cgtacttgtt aaaatagata
     9301 tgagttggcc tattcctatc acggccaaag ttgatttcca atgattcatt gtgctaatat
     9361 ttcatgcgtt tatagataag tactttcgta cattaagcaa aacgaaattc tatccacaca
     9421 aaaaacttgt attataatcc actcctgacg ttggaataca ataacaaata ctttcaggac
     9481 gatgtaaagt cctgaaaaat caaactgaat ggatagataa atattagtct tttctcatcg
     9541 gattctttta atatcgctac tcttttatta tgtagtggtt gtattatctt aaataaaaca
     9601 aaaacaccga ctttacattc ttgggtgtaa aactgggtgt ttgttttgca atctgctgat
     9661 tttcagcgtt tgttgcggag agacagggat tcgaaccccg ggtacctcgc ggtacaacgg
     9721 ttttcaagac cgccgcaatc gaccactctg ccacctctcc aaaacttcct tatcagaagt
     9781 gcttttcgtt aaaagcggtg caaaggtacg aagatatttt aaacttgcaa gagttttcac
     9841 taaaaattta atctaatctt ttcctaagga tagcaattaa taggtatttt atgttgaaaa
     9901 gcataaaata gagcatattt atgctgatta tatgaaaaat gattgtaact ttgtgcgctc
     9961 taaagaatag gataactaca acctctaatt ttatcatttt atggaattaa acaagatctt
    10021 taaagacggt ctttggagca gcgaaatcaa cgtcagagat ttcgtaagtc ataacatcac
    10081 tccgtattac ggagatgctt cattcctcga aggacctaca gaacgtacca aagccgtatg
    10141 gaaccgctgc ctcgaagcac tggcagaaga aagagaaaac aacggtgtcc gctcattaga
    10201 taatgttacc gtatcaacca tcacttccca caaggccgga tatatcgaca aggaaaacga
    10261 actgatcgtc ggcctgcaga cagacgaact tctgaaacgt gccatcaagc ctttcggagg
    10321 tatcaatgta gtcagcaaag cctgtcacga aaacggcgtg gaagtggacg accgcgtaaa
    10381 agatattttc actcactacc gcaagacgca caacgacgga gtattcgacg tatatacgga
    10441 agaaatccgt tccttccgtt cgctgggatt ccttaccgga cttcccgaca attatgcacg
    10501 cggacgcatc atcggtgact accgccgtat ggctctttac ggcatcgacc gtctgatcga
    10561 agcaaagaag gaagatttgc acaacctcac cggtccgatg acagaggccc gcatccgcct
    10621 gcgcgaagaa gtggcagaac agatcaaggc actgaaagac atgaaagtga tgggcgaata
    10681 ctacggtctc gacctgagcc gtcccgctta cacggcacaa gaagccgtac agtgggtata
    10741 tatggcttac cttgccgccg tcaaagaaca agacggtgcc gccatgtcac tgggtaacgt
    10801 ttcttctttc ctcgatatct atctggaata tgaactgagc aaaggaacca tcaccgaatc
    10861 attcgcgcaa gagctgatcg accagtttgt catcaaactg cgtatggtcc gccacctgcg
    10921 tatgcaatca tacaacgaca tctttgcagg cgacccgacc tgggtaaccg aatctctggg
    10981 cggacgtctc aacgacggac gtaccaaagt gacaaagacc tccttccgtt tcctgcagac
    11041 attgtacaac ctcggccctt caccggaacc gaacctgacc gtactctgga gcccggaact
    11101 tccggaagga ttcaaagaat tctgtgcaaa ggtttctatc gacacttctt ctatccagta
    11161 cgaaaatgac gacctgatgc gcgaagtacg tcagtccgac gactacggaa tcgcctgctg
    11221 cgtatcatac caggaaatag gtaagcagat tcagttcttc ggcgcccgtt gcaacctggc
    11281 caaagccctg ttgcttgcca tcaacggcgg acgttgcgag aataccggta cagtcatggt
    11341 gaagaatatc cccgtactga ccagtgacac gctgaagttc gaagaagtaa tggacaacta
    11401 caaaaaagtg ctgaccgaaa tcgcccgcgt atataacgaa gcgatgaaca tcatccacta
    11461 tatgcacgac aagtattact acgagaaggc ccagatggct cttgtagata cgaacccgcg
    11521 catcaacctg gcttacggtg tagccggact ttccatcgcc ctcgattcac tgtctgccat
    11581 caaatatgcg aaagtaactg cccgccgcaa tgatatcggt ctgacagaag gcttcgacat
    11641 cgaaggagaa ttcccttgct tcggtaacga caacgacaag gtagaccacc ttggcgtaga
    11701 cctggtatac ttcttcagcg aagaattgaa gaaattgcct gtttacaaga atgcccgtcc
    11761 taccctctcc ttgctgacta tcacttccaa tgtgatgtac ggcaaaaaga ccggtgctac
    11821 tcccgacgga cgtgccaaag gtgttgcctt cgctccgggt gccaatccga tgcacggacg
    11881 cgacaagaat ggtgcgatcg cttctctgag ttctgtagcg aaacttcgtt accgtgactc
    11941 acaggacggt atcagcaaca ccttctctat cgttccgaaa tcactgggtg ctacggacga
    12001 agaccgtatc gagaacctcg tgacgatgat ggacggttac ttcaccaaag gtgcccacca
    12061 cctgaacgta aacgtactga accgtgatat gctgtacgat gccatggagc atccggaaaa
    12121 ctatccgcag ctgactatcc gcgtttccgg ctatgccgta aacttcgtga agctgagccg
    12181 cgaacaccaa ctggaagtta tcagccgtag cttccacgaa cgtatgtaat ctattactct
    12241 atatgatgat aaacgtacat tcatacgaaa gtatgggaac attcgacggg ccgggcttac
    12301 ggctcgtcgt ttttcttcaa ggatgcaact tccgctgcct ctattgcgcc aatccggata
    12361 cgatagcagg aaagggaggc acgcctaccc caccggaaga aatcgtccgc atggcaatga
    12421 gccagcgccc cttcttcggg aaacgagggg gaatcacttt ctccggaggc gaaccgacgt
    12481 ttcaggcgaa agcactcgtc ccgctggtcc gcgaactgaa agaaaaaggc atccatgtct
    12541 gtctggacag caacggagga ctttggaacg aagacgtaga agaattattc agactgaccg
    12601 atcttgtgtt attggatata aaggaattca accctaaccg ccatcagacg ctcaccggaa
    12661 gaagcaacga gcaaaccatc cgcacggccg cctggctgga agaacaggag aaacctttct
    12721 ggctacgcta cgtgctagtg cccggataca gcgattttga agaagacata cgcgcactgg
    12781 gagaagcact cggaaaatac aagatgatcc aacgggtgga aatattgcct taccatacac
    12841 tgggcgtaca taagtacgaa gcgatgggac aggaatacaa gatgaaaggg gtaaaagaaa
    12901 atacccccga acagcttgaa aaagctgcgg aggtattcaa agagtatttc actacggtgg
    12961 tagttaatta atggagaatt ctccaatgac ctcaaagcaa ggacattctt taatccgttc
    13021 ccaaggatct acgatcccat tatagttggt gtcgggactt aaatcccgat gccctactac
    13081 tttagcttcc ggataacgct gcaacaattc gtgtaccaag cgatgtagcg cctccttctg
    13141 acggggtgta cgcgtatccg cagcttttcc attctcatca agaccgccct cataacatac
    13201 acctaagctg atcgcattat agccacgtgc atgagctccg accgtatctt catcccgcat
    13261 cggctcaatc tcgcccgact tgcatatata ataatgatac ccccagcacg aaaagccacg
    13321 ataacggtga gccgtatcca catcctttgc cgtaaagtcg caatcgacac gggtggcgga
    13381 acaatggatc acaatcagac taatctttct catgttcctt ttccctttcc gtcgttttca
    13441 ctttgcacac ctccttacaa gtagtatgat agcgcacttc tctcaccacc ctgtcccgct
    13501 ttctctttcc gaagaaagga atcagataca tgatcacatc taaaatccgg tttactattt
    13561 ctttcatctt atcaaaatat taatggaagt tattctaatt cgttattacc ttgacccgtc
    13621 tgccaattat accgtagggt ccggagcctc ttcatcaccg gagccatcac caccggaatc
    13681 cggattcttg tcagggtctt ctcccccgcc atcgcctgca cccgcctgcg ccaccgcacg
    13741 agtctgcact tgctgataac tcagaatctt catcaactcc gccagcgtct taccggggcg
    13801 gaaaataaga tgcgccccct taatcattga accggaaaat tccttgaccg atgccgcacc
    13861 ttcactgttg agtcctatct gcaaactgcc caaatcgccc agtctcgcaa ttcttcctgc
    13921 cttcaacgca cgtttcactt cgtaaagaat acccgaaata gccgcacgta catccgtttc
    13981 cgtacaagta gaacgactgg tgatcgcttc gcacaactct tcaaagtcca gctcacccga
    14041 cgcctgcgcc tgtgcataat actttgccgg ttcgctcttt tttgcaggat tcttgcgcgg
    14101 caccactgaa taagatactg tcattgccat aataaaataa ttttaaagtt tataatacat
    14161 aggatgcatc cccttcttgt taacagcaca aagataagga tagccggaca agctatattc
    14221 cccaacgaag tttcttgatt cccaacgaat aaaaacgaag tcaaaccttt gaaaaacaag
    14281 gaattttatg taactttata gcataaaaca agaagaaaac atcatgaatt acaaagaaga
    14341 ttctttcctt atccgcacct ataccaaagc ggaactggct cacctttaca atccccatgt
    14401 ctgcctcaaa gttgctttac aaatacttcg tcgttggatt atttacaacc tccctctcct
    14461 gcacgaactc gaacaggaag gctaccgcgc acgcaaccgt ctcctttcgc cgaaacaagt
    14521 ggcaactatc atacactttt tgggcgaacc gtagtaactt attgccattt tatacaaagt
    14581 tcctttacac atttccgcaa agaagttcct ttgcatcgac aaacaataat caaaataaaa
    14641 atgaaacatt tcaccatatt tcaaggtttc tactacgcaa tagcagagat gaccgaagaa
    14701 gaaatagtgt ccactatcgg cagttttacc taccgggaaa aagtcgaaga aatacgccgc
    14761 atctttgcag agcaaggaga aaaggctgcc aatgagaaga aaaaagaatt gccggcaatc
    14821 gccttctccg ccagctaccg aggaaggcgt accaaagtga acctcgtcaa atatctggga
    14881 cacatcgtga tagacatcga ccacctcagc aaagaagaat tggcacgcat cctccctatc
    14941 atcaagagat gcaattacac ccgcatcgcc tttatcagtc ccaaagggat gggcgtgaaa
    15001 atcatagtac gcgcatgcca tccggatgag acattgcccg aaacccttca ggaaatagaa
    15061 gacttccatc atgcagctta caccagactc gtttcttttt acaccgaact ctgtcagata
    15121 gaaatcgaca cctccggcca ggatgtagca cgcacttgtc tgttctctta cgatccggag
    15181 atttatttca atccgaacgc tgacgctttt cttgtagatc aacctcaggc atcctacaag
    15241 gtttcaaatc gtaaaaatct ctccggcagt aaacaacaga ctcctccgga cggccccccg
    15301 acgaatgaag acacagcgct caacgcccat tccgccaacg cttctctggt gctgacttta
    15361 acctactatc acaacaagtc cgaaaaatac atagcaggca accggaacaa ttatctgcac
    15421 catctctcat gtaccttcaa tcgctacggc attccgcagg aggaagcatc cgcttttatc
    15481 aaaagccagt ttacagactt tccggcagac gagacagtct ctttgatcaa tagcgcctac
    15541 gctcataccg acgaatttaa tacctgtaaa ctgaatggca cgcagaaacg aatattacgg
    15601 atagagcaat atatcagcga gcactacgaa acacgctaca acgaagtgct gcatatcatg
    15661 gaatatcgca gaaggcatcc cgacaccgag aaaccggagc ctttccgcat cttggatgag
    15721 atgatggaaa acagtatctg gatagaaatc aacgaactgg gatatccctg cactgtcaaa
    15781 acaatcgaaa atctgattta ctccgatttc agccagtcgt atcatcccat tcgcgagtat
    15841 tttgaattac tgcccgaatg ggacggaacc gattatatcc gtatcctggc ggatagtgtc
    15901 cagacgagtc atcaggagtt ttgggcggaa tgcctggaac gttatctggt ggcgatgtgc
    15961 gcagcggcta ctcaggagaa tattgtcaat cacacggtac ttctgctatg cagcgagata
    16021 cagaacatag gaaagactac ctttatcaat aatctcctgc ctcccgaact gcgtgcttat
    16081 ctctctaccg gactaatcaa ttcgaacaat aaagatgatt tagccaaaat aacgcaggcc
    16141 atgctgatca atctcgacga gtttgaaggg atgagcggcc gggaactgaa tgcattcaaa
    16201 gatttggtaa cgcgcaaagt gatcagtttc cgtctgcctt atgcacgccg ttcgcaaaac
    16261 ttccctcata cggcctcttt tgcaggaacc tgcaattatc aggaagtgct tcacgacacg
    16321 acaggcaacc ggcgtttcct ttgttttcat ccttattcca tccaatttat taccatcaat
    16381 tatgcgcagc tctatgctca gatcaaatat ctgctgaata agccgggata tcaatactgg
    16441 ttcacgcaag cggacaatga acggcttgaa gagaataacg aggctttcat ctttcattca
    16501 ccggaagaag aaatggttct tacgcatatc cgcaagccgg aacgtttcga gaaggtttat
    16561 tatctgactg tcagtgagat tgcggaacta atacgtgagc gtaccggtta tcagtattcc
    16621 atcggatcaa aaatacagtt ggggaaggtg atgactaagc accattttga atctaaaaaa
    16681 ggaaataacg ggcgccgata tgccgtattt attatagata tcgagcaggt aaaatcaaac
    16741 aggctgtatg aatagaagcg ggaaagcctt gtgaatatag caaaatgcag agtcatcttg
    16801 acagatactc tgcatttatt gtttttacaa aatcattgaa aattcgattt tacagcctaa
    16861 cgcattcatt atacgataga aagtagatac tttaggctct gtctgaccac tttctactct
    16921 tgaaatataa gaacggtcag aaccgatacg ccgggctaat tcagcctgag tgattttagc
    16981 cttttttctt gcgtcctcga taatctgtcc tgtataaaag gcgtaggcct tttcttctgc
    17041 ctctgcacga gaagctgttc cttccttacc aaaacgctca tctattaatg cactgacatt
    17101 aaagaattcc tcatttgttt ttgcttccat aatactcctt tcttaatatc tttgctttat
    17161 caatttcttt ctttggtgtt ttttcggttt tcttttgaaa accgttaaac agaatcacaa
    17221 tacgcccttc gtcgaaacaa aagaatattc tatatatatt gctttggtac tcgatacgaa
    17281 gttcataaag tccttcttct atcaaccgca taaatttcaa aggtattctg tcttgtgtct
    17341 gcaataacat tagcacatac aatatcctgt ctcttataca atctgacgct gccgagacaa
    17401 tgcaagtgta gatctcggtg g
//
