LOCUS       gnlProkkaJIDIIJKE_61   11821 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JIDIIJKE_61.
ACCESSION   gnlProkkaJIDIIJKE_61
VERSION     gnlProkkaJIDIIJKE_61
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 15:14:53
            Original ID  :: gnl|Prokka|JIDIIJKE_61
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11821
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1281
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 70.6;
                     E-value: 1.6e-21)"
                     /gene_kind="transport"
                     /locus_tag="ctg61_1"
                     /transl_table=11
                     /translation="MVVTAEAILNRFTNKLEIRGAVYRPGIYQLSGKLNTIRELVNEAQ
                     GLTGDAFLNRAVLYRQREDLTSEVVQIDIRSIMDGTSPNLALMKNDILYIPSIHDLEDR
                     GNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKEAASTVRIDVSRRIKNPRSTADNDT
                     IGQMYTFSLKDGFVIDGQPGFILQPYDEVYVRRSPGYQAQQNVVIDGEILFGGNYAMTN
                     REERLSDLVNKAGGPTSLAYLRGAKLTRVASAGEKKRMGDVIRLMSRQLGEAMIDSLGI
                     GVEDTFTVGIDLEKALTNPKGSADLVLREGDVVFIPKNTNTVTINGAVMVPNTVSYMKG
                     KDVDYYLNQAGGYSDNARKSKKFIVYMNGQVTKVKGSGKKQIEPGCEIIVPGKAKKKGN
                     IANILGYATSFSSLGMMIASIANLIKK"
     protocluster    1..11821
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2507:6821]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2508..6821
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11821
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11821
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             1296..2444
                     /locus_tag="ctg61_2"
                     /transl_table=11
                     /translation="MSEQRQDKNLLSEPHKTESDEIEIDLVDIFRKIIAIRKKLYKAVG
                     IGFIIGIIVAVSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVLFGKSLLASLRKELKNKEIEQDK"
     CDS             2508..3227
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 4.2e-17, bitscore:
                     52.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLIAPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             3248..4549
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 209;
                     E-value: 1.4e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_4"
                     /sec_met_domain="CTP_transf_like (E-value: 2.3e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 9.7e-122, bitscore:
                     395.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-63, bitscore:
                     204.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKTILENERALEVRELCMPIKEILELIPGTK"
     CDS             4566..5690
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.3e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             5700..6821
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg61_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_6"
                     /sec_met_domain="Aminotran_5 (E-value: 1.8e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        5790..6797
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg61_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg61_6_Aminotran_5.1"
                     /locus_tag="ctg61_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             6818..7291
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 73.7;
                     E-value: 2.7e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYSNIY
                     LGKNAEIRSGCYLIARDKIIIGENSTLAYGTTILTTADPNGPYNALAVLYPYKKAPVVI
                     GDNVWIGANVTILPGVTIGDYVVVAAGAVVTKDVPSGVLVAGVPAIVKKRFNK"
     CDS             7288..8733
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_8"
                     /sec_met_domain="Polysacc_synt (E-value: 9.6e-33, bitscore:
                     103.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKTSLKNKAICGIFWSAVERFLSQGIQFVVTVIMARFLLPSDY
                     GMVGMLAIVLQLSQTLMDSGFTNALIRYKERTEIDYSTVFFFNILASLVIYFLIFFLAP
                     YISWFYKIGQLVEITRILSIVIVLNSFAIIPKTKLIIAVDFKTQSKVSFIAALVSGIIG
                     IWAAYLDFGVWALVGQTLVNGLLIVVLYAYFCRWKPLWIFSLKSFRLLFAFGSKLVLAN
                     ILNTLYKNLYAIVIGKKFSSVDLGFYTRAEQFAQFPSYNLSAIISRVTYPILSLVQNDN
                     DRLSALYRKYVRLSSAFIFPLMILLIVIAQPLVLLLLTEKWIGVVVLLQILCLDWMFDH
                     LSSINLNLLYVKGRSDLALRLEVIKKVLATGILLLSIPWGIVGMCWGRVMYSLIAVYLN
                     TYYTESLIKLSLIRQMRDILPSFFLALIMGGGTWYMILLLEGEIVQIVVGSVIALLLYG
                     TLLYCFSRSLFDEIWAVILKIKR"
     CDS             8733..9455
                     /locus_tag="ctg61_9"
                     /transl_table=11
                     /translation="MDKLSLIISKIRRNHWYRTYMRPIYLFVYGNRKLKNRNRIFLQYS
                     QELLTNFHQAMNEVGIPYWLEFGTLLGAVREHSFISHDFDLDVGLFKEDYSDIIREVLK
                     KYGFKRIRCITALDFIDAYEETYLYKGVTIDLFLFSREKNCDGVYCYDFVPVYSDIKRT
                     KKGDNAIRRIHFPRIDLIEYSFIGINTFVPENYEEHLCMHYGKDYMIPNPHWKDSDAQH
                     TDIFYGREIRIELFDKSK"
     CDS             9469..10482
                     /locus_tag="ctg61_10"
                     /transl_table=11
                     /translation="MFYLFFLLIVLFLLYIQSRKRQYSTVAGICVPIIIIFVVICRYRV
                     GYDYLTYYTLIENEEEAQILYLFSPLSIVWAEIALYFESPQMLFVLFGLPTFALLIFTL
                     KKYSKDYALSVTILICFFFFTSLSIIRQALALAICFYGYRFIVKRSLIKYILCILIAAL
                     FHPSAGVAIIIYWLPFLKFRLVVLLSIISIVAKPLFFYMLNILGVYTSYLDGKMDIEGG
                     KYTQLIYFLLFIICFVLGSKNIDKNKCNLFNVLLLSFVFVSFLGAHLGGRIAFYFNIYY
                     CLLIPKVVKGLDGQLREQVKLLSYFLCISYFLLYLFVPFIKGVPSYYIPYKFIFFK"
     CDS             10487..11446
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 57.2; E-value: 3.2e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_11"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-42,
                     bitscore: 135.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLISIIVPCYNSERYLSDCLLSILNQTYVNWEVICIDDGSQDNTL
                     SILNHYATLDERFKIISQSNAGVSVARNKALSQCQGEYICFVDSDDLIEPNFLITLLQL
                     ISHQADLAICGFTRSMVFCMDDAQGYIEMSGKRCIERIILDKSFNPQICCMLFRHNIIK
                     EKQLEFVIGCTRGEDREFILKYLVYSNKVCYTNNLLYHYRVNDQSAMAIFSIKSLTSIE
                     ASQRTVNYYKKVNYSVRGLEFEFSRTLWKFMILAILSGQNDLYQIIREKYDLKRQMEHL
                     YSHPGLSEKLTARLFVWNEALFKWVFSIIRYLYKKRWR"
ORIGIN
        1 gacgttgtaa cagccgaagc catccttaac cgcttcacaa acaaactgga aatccgtggc
       61 gctgtctatc gtcccggcat ctaccagctc agcggtaaac tgaacacgat ccgcgaactt
      121 gtcaatgaag cccagggtct gaccggtgac gctttcctga atcgtgccgt cctttatcgc
      181 cagcgtgagg acctgaccag tgaagttgtt cagatagaca tcaggtctat catggacggt
      241 acttccccga acctcgccct gatgaagaat gacatccttt acattccgag cattcacgat
      301 ctggaagatc gtggcaatgt cacagttcac ggtgaagtcg cgcaccctga ttcctatccc
      361 tacgctgata acatgacact tgaggatctg atcatccagg ccggtggctt gaaagaagcc
      421 gcctctactg tccgcattga tgtgtcgaga cgaatcaaga atccccgtag taccgcggat
      481 aatgatacta tcggtcagat gtataccttc tctttaaagg atggttttgt catcgacggt
      541 cagcccggtt ttatccttca gccttatgac gaagtttatg tccgtcgcag tcccggttat
      601 caggcgcaac agaatgtagt cattgatggt gaaatattgt ttggaggaaa ttatgccatg
      661 accaaccgtg aggaacgtct ttccgatctg gtgaataaag cgggtggtcc taccagtctt
      721 gcctatctcc gtggtgcgaa attgacccgt gtggcaagtg cgggtgagaa gaaacgtatg
      781 ggtgatgtga ttcgcctgat gagcaggcaa ttgggtgaag ccatgattga ctctttgggt
      841 attggtgttg aggatacctt tacggtaggc attgatctgg agaaggcttt gactaatcct
      901 aagggtagtg ccgaccttgt cctacgtgaa ggtgatgtgg tctttatacc taagaatact
      961 aatactgtaa ctatcaatgg tgctgttatg gtccccaata cggtttctta tatgaaggga
     1021 aaggatgtgg attattacct gaatcaggcc ggtggctatt ctgataatgc aaggaagagt
     1081 aagaagttca ttgtttacat gaatggtcag gtgacgaagg ttaagggtag tggtaagaaa
     1141 cagattgagc cggggtgtga gattattgtg cctggtaagg ctaagaagaa agggaacata
     1201 gctaatattt taggttatgc tacttccttc agttctttgg gtatgatgat tgcttctatt
     1261 gctaatctta taaagaaata atagaattta cttttatgtc agaacaacga caggataaaa
     1321 acttgctctc tgaaccacac aagacagaaa gtgatgagat agaaattgat ttggtcgata
     1381 tctttcgcaa gattattgct attcgtaaaa aattatacaa agccgttgga attggtttta
     1441 ttattggaat aattgtagcg gtaagtatcc ctaaacagta tacagtaaag gttacccttt
     1501 ctcctgaaat gggtaatgcg aaggggagta atggtttagc cggacttgct gcctcgtttt
     1561 taggagatgg ggctctaata ggggaaagca cagatgcctt gaacgcttct ctttcagcag
     1621 atattgtttc ttcaactcct tttttattgg aacttttaga aatggaagtc tccgtttcta
     1681 aaaaggatga taaaatgact ttggggtctt atctcgatga agagtcatct ccttggtggg
     1741 attatcttat aggttttccg ggcatagtaa taggaggagt taaatcatta ttcggagaag
     1801 atacggttcc tgccagtgga gggcggcaag gaactatcga attgacgaaa gaagtaaatg
     1861 agaagattaa ttttcttaaa aagaagatta gtgcatccat tgataagaaa accgccataa
     1921 cgagcattac ggtcacctta caaaatccgc agatcactgc ggttatagca gattctgtcg
     1981 ttcataaatt acaggaatat attattgggt atcgaacttc aaaagtaaaa gaagactgtg
     2041 cgtatttgga acggttgttt aaagaacgtc agcaggaata ttatgctgct caaagaaaat
     2101 atgcggatta tgtagacgcc catgataatg tggttcttca aagtgtacgt gctgagcagg
     2161 agcgtttaca gaacgacatg agtttggctt atcagatata tagtcaggtt gctaatcagt
     2221 tgcaggtatc cagagccaaa gtacaggagg aaaagccagt ctttgcagta gttgagcctg
     2281 ccgttgtacc tttgaaacct tcaggtatgg gactcaaaat ttatatttta ttatttgtgt
     2341 tcctgtccgt atctggtact ctcgtgtggg tgctttttgg caaaagtctg ctggctagct
     2401 tgagaaaaga actgaaaaat aaggagatag aacaggataa atgatgctaa aacgtcgttt
     2461 acaacattct tatatcaatt aaattcactt actatattat taaacgaatg atacgtacag
     2521 ctatgataat ggctgcgggc atgggaaccc gttttggcca atatacagaa ttgataccta
     2581 aagggttcgt caaagtggga ggtattccaa tgatagttcg ttctattgat actttgttat
     2641 catgtggcat tgagcgaatt gtaatcggta caggatataa acaagaagtt tatgaagaat
     2701 tgaagacaga ctatcctatg cttgaaacct gttttagtcc tcgttatgct gaaacaaata
     2761 gtatgtatac tttatataat acgcgggaga ttctgggcaa tgatgatttt ttattgttag
     2821 agtcagattt gatttttgag aaacaagcaa taatgagctt attggagtgt cctgcggcag
     2881 atgcaatgct aatagctcca gtgacaaagt ttcaagatca gtattatgtg gaacatgatg
     2941 ataattttcg cctttcttca tgttctgtca ataagaataa actaaacgct aaaggcgaat
     3001 tggtcggcat ccataaacta tccggttcct tttacaaaat aatgtgtgct gattatgcga
     3061 gtattgttga tgaacaaccc aatttgggat atgagtatga attactacga atatcttgtt
     3121 ctcaatctcc tgtttatgtg cataaagtag aagggctgaa atggtatgaa atcgatgaca
     3181 tatcagattt ggaatatgca gagaaatata ttgttccgta ttgttaatta aaataatata
     3241 tcaaattatg agtaagacag tttatattgg gatgactgcg gatattatgc atccaggact
     3301 tatccgcatt attaatgagg ctactaaata cggtgatgtt ataattggtc ttcttacaga
     3361 taaagctatt gcggagcata aacgccttcc ttatctgacc tatgaacaac gaaaagaggt
     3421 agttcagaat attaaaggcg tatgtaaagt tgttcctcaa gaagaatgga gctatgttga
     3481 gaatctcaaa cgcattaaac ctgactatat aattcatggt gacgactgga aaaccgggcc
     3541 tttacgtgaa gaacgtgtgc gcgtatttga agtgatgaat gaacagggag gaaaggttat
     3601 cgaaattcca tatactttgg gaattaattc atcttctttg gataaagata ttaaggctat
     3661 aggtacaacc cccgatgtac gtttaaaatc acttcgtcgt ttgataaatg ccaaacccgt
     3721 agttcgtatt ttggaagctc atgatggact atgtggcttg ataattgaaa atcaggaaat
     3781 attaaaaggg gataagaggg aagtatttga cggaatgtgg tctagtagcc ttacggattc
     3841 aaccagtaaa ggtaaacctg atattgaggc ggttgattta actacccgat tgcaagattt
     3901 gaataatatt ctggagtgta ctactaaacc tattattttt gatggagata caggtggtaa
     3961 aattgaacat ttcgtattta cagtacgcac tttagaacgt catggaatct cagctataat
     4021 aattgaagat aaagttggat taaaaaagaa ttcattgttt ggtacggatg ttattcaaac
     4081 tcaagataca atcgaaggtt tctgtaataa gatcaaagca ggaaaggcat ctcagattac
     4141 tgatgatttt atgattatcg ctcgtattga gagccttata gcgggaaagc cggtaagtga
     4201 tgctttagag agagcttttg catatgtcca agcgggagcg gacggtatta tgatacatag
     4261 caaaaataag tcgggtgaag atataaaaga attttgtttg gcgtttcgaa aacagtatgc
     4321 tcatgtacct atcgtggttg tgcctactac atatgatcat atttatgagt ctgaattgtg
     4381 tgattggggt gtgaatataa ttatttatgc taatcatatg cttcgtgccg cttatcctgc
     4441 tatgatgaat gtcgcaaaga caatattaga gaatgaacgt gctttagagg tgcgcgaact
     4501 gtgtatgccc ataaaggaaa tattggaact gattccgggt actaaataaa aagaggaata
     4561 tcattatgtt aagcgtagaa aaagtttatg aaacgtttct gagtcatgac gttgattttt
     4621 ttacaggagt tccagactca ttactaaaaa atatttgtgc ctatatcaca gaccatactt
     4681 cacgtgagaa acatatcata gctgctaatg aaggtgcggc tgtaggaatt gcttcaggtt
     4741 attatatggc atcaggtaag gttcctgtgg tttatatgca aaattccggc ttgggtaata
     4801 ctgttaatcc tctgctgtct cttgcagatg aacaagtata cagttttcca atgcttttga
     4861 tgattggctg gcgtggtgaa ccgggaacaa aagatgaacc tcagcataaa aaacagggtg
     4921 aggtaacttt agatttgttg aaagcaatgc ggattcctta tataattctt gattcaaatg
     4981 agaatgatgc atttattcag ctccatgata tcatacaatc agcaaaaact aagaatattc
     5041 ctcatgcaat aattattcgg aaagatgttt ttggcaaata taaacttcaa aaagagttcg
     5101 gatgtaatta tcctttatct cgtgaggatg ctttgcaaat agttgtggat tatctgcctg
     5161 aaaattcagt ggtcgtttct actactggca agctttctcg tgagttattt gaatatcgag
     5221 aaatgaaaga gcaaggtcat gaacatgatt ttctcacggt aggctctatg ggacatagtt
     5281 catcaatctc tttgggtatt gctatagcaa agcaagatag acctgtttat tgcttggatg
     5341 gtgatggagc atttattatg catttagggg caattagtaa cattggcgat ttatctccta
     5401 aaaactatta tcatattttg tttaacaatg gtgctcacga gtctgtagga ggacagccta
     5461 ctttaggatt tagtttagat attccggcta ttgtccgggg gagcggatat aagcatactt
     5521 atactgtttg tacaaaagtt gaaattgaag aagcaatgaa gcagcttcca aagttatgtg
     5581 gtcctgtttt gttggaaata aaggttaaaa tagattctcg ggagaatttg ggacgtccca
     5641 cgactactcc tatagagaat aaggagcatt ttatggattt tttaaaataa atatattcga
     5701 tgaaaataga aagaaaaata ttattaaatc ctgggcctgc cactactact gacagtgtaa
     5761 aaatggcaca agttgttccg gatatttgtc ctcgcgagaa agaattcgca ggtatgatga
     5821 aacaacttcg ggacgatttg gtcagagttg ctcatgggaa tttggaaaaa cataccgctg
     5881 tattattttg tggctcagga accatcaata ttgatatatg tctaaattct cttcttcctg
     5941 aagacaaaag ggtgcttata gtgaataatg gggcatatag tacccgtgct gtagaagtgt
     6001 gtcaatatta tggtttgcct catattaatt tggaattttc cgtttacgaa cgtcctgatt
     6061 tatcggtggt ggaaaatgtg ttgcaagaaa atcctgatat agctatggtt tatactactc
     6121 atcacgagac gggtacagga attctgaacc ctattcgcga gatgggcgct atagctcata
     6181 aatatcaggc taaatttgtc gtcgatacta cttcttcttt gggcatgatt ccttttgata
     6241 tagagaaaga taatgtggat ttttgtatgg catctgctca aaaaggactt caagcgatga
     6301 caggtctttc ttttattata ggcaatgagg aacagattaa gttttcaaaa aaatatccca
     6361 agcgttctta ctattgtaat ctttatttgc agtatgagaa ttttgagaga acaggtgaaa
     6421 tgcattttac tccaccggta caaactattt acgccactcg tcaggcatta aatgaatatt
     6481 ttgaagtggg cgaagaagct aagtttgccc gtcacaaaag agtttttgag gctattcatt
     6541 caggtataaa tgaaattggt cttaaaagtg taataaagcg tgaatggcag tcaggactgg
     6601 ttgtctcagt tcaataccca gaagatccca actgggattt tgagaaaata catgattatt
     6661 gttatgagcg tggatttacg atttatccag gtaagatatc aactgaggat acttttagaa
     6721 tctgtgcttt aggagagata gaagtagatg atattgagaa cttctttaaa gtactaaaag
     6781 ctgcattaaa tcattataac gtcacattac cgatgtcatg attgcagaaa tattattgaa
     6841 gattcgtcat ttttattttt cccttcgtgg tatacacttc catccggaaa gtgttatttc
     6901 tggagtgcct attcgtagct ttcgcttagt aggcaaatat agcaatatct acttaggtaa
     6961 aaatgctgaa atacgttcag gctgttatct gattgctcgt gataaaatca ttattggaga
     7021 aaactcaaca ctcgcctatg gaacgactat attgacaact gctgatccta atggaccgta
     7081 taatgcatta gcagttcttt atccttataa aaaggcaccg gtagttatag gagataatgt
     7141 ttggattggg gctaatgtta ccatccttcc tggagtaact attggtgatt acgttgtagt
     7201 agcagctgga gctgttgtaa caaaagatgt accttcagga gtattggtag ctggtgtacc
     7261 agctattgtg aaaaaacgtt ttaataaatg aaagaaaaaa cttctttaaa gaacaaagcc
     7321 atatgtggaa tcttttggag tgcagttgaa cgatttttat cacaggggat acagtttgta
     7381 gttacagtca ttatggcgcg ttttctattg ccatctgatt atggaatggt aggaatgtta
     7441 gcaatagttc ttcaattatc tcaaacgtta atggatagtg gttttactaa tgcccttatt
     7501 cgttataagg aacgtactga aattgattat tcaacagttt tcttttttaa tatattagca
     7561 tcattagtta tttattttct aatttttttt ctagctcctt atatatcgtg gttttataaa
     7621 ataggtcaat tagttgagat tactagaatt ttatctattg ttattgtttt aaattccttt
     7681 gcgattattc ctaaaactaa attaataata gctgtagatt ttaaaactca atcaaaagtc
     7741 tcatttattg cagctttggt ttcaggtatt attggcattt gggctgcata tttagatttt
     7801 ggagtttggg ctttagttgg acaaacttta gtaaacggat tgttgattgt agttttgtat
     7861 gcatattttt gtagatggaa accattgtgg atattttcat tgaaatcgtt tcgtttatta
     7921 tttgcttttg ggtcaaaatt agtattagct aatattctta atactttata taaaaatctg
     7981 tatgctatag ttataggaaa gaagttttcg tcggttgatt taggatttta tactcgtgcg
     8041 gaacaatttg ctcagtttcc ttcatataat ttgagtgcaa taatttctag agtgacatac
     8101 cccatattga gccttgtgca aaatgataat gatagattat ctgctttata taggaaatat
     8161 gtccgtttat cttctgcttt tatctttcca ttgatgattt tgttaattgt catagctcag
     8221 ccactggtat tattgctttt gacagaaaaa tggataggag tagttgtatt gcttcaaata
     8281 ttgtgtttag attggatgtt tgatcatttg agtagtataa atttgaattt actatatgta
     8341 aagggacgtt cagacttggc tttacgttta gaagttataa aaaaagtgtt agcgacgggg
     8401 atccttcttc tatctattcc ttgggggatt gtaggtatgt gttgggggcg tgttatgtat
     8461 tcattgattg ctgtgtattt gaatacttat tatacagaat cattgattaa attaagtctt
     8521 attagacaga tgagagatat actaccaagc ttttttttag cattaataat gggaggaggt
     8581 acttggtata tgattttatt gttagagggt gaaattgttc aaattgtagt aggaagtgtt
     8641 attgctttat tgctatatgg aacgttgttg tattgctttt ctcgatcctt gtttgatgaa
     8701 atatgggcgg ttatattaaa aataaaaagg taatggataa actgagtttg attattagta
     8761 aaatacgacg gaatcattgg tatagaacct atatgcgtcc tatatattta tttgtttatg
     8821 gcaatagaaa attgaagaat agaaatagaa tatttttgca gtattcacaa gagctgctaa
     8881 ctaactttca tcaagcaatg aatgaagtgg gaattcctta ttggttagaa tttggaactc
     8941 ttttaggtgc tgttagagaa cacagtttta taagtcatga ttttgatctt gatgtgggcc
     9001 tttttaagga agattattca gatataataa gagaggtctt aaaaaaatat ggtttcaaaa
     9061 gaataaggtg tataaccgcc cttgatttta ttgatgctta tgaggaaact tatctttata
     9121 aaggtgtgac aattgatctt ttcctttttt caagagagaa aaattgtgat ggggtctatt
     9181 gttatgattt tgttccagta tattcagata taaagagaac taaaaaaggt gataatgcaa
     9241 tccggagaat tcattttcct agaattgatt tgattgaata ttcatttatt ggaattaata
     9301 cttttgttcc tgaaaattat gaggaacatc tttgtatgca ttatggtaaa gactatatga
     9361 ttccaaatcc tcattggaaa gattcagatg cgcaacatac tgatatcttt tatggtagag
     9421 agattagaat tgaattgttt gataaaagta aataatagta gataatacat gttctatcta
     9481 ttttttttac taattgtgct atttttgtta tatatacaaa gtaggaaaag acaatattct
     9541 actgtagcgg gaatttgtgt tcctattatt ataatttttg ttgtaatttg tcgttataga
     9601 gtggggtatg actatttaac gtattataca ttaattgaaa atgaagaaga ggcacagatt
     9661 ttatacttat tttctccttt aagcattgtt tgggcagaga ttgctttata ttttgaatct
     9721 ccacagatgt tatttgttct ttttgggctt ccaacatttg ctcttctaat atttacttta
     9781 aaaaaatatt caaaagatta tgcgttatca gtaactattt taatttgttt cttctttttt
     9841 acatcactca gtattattcg acaagctttg gctttggcta tttgttttta tggttatcgt
     9901 tttatagtaa aacgttcact aattaaatat atattatgta tattgattgc agctttattc
     9961 catccttctg caggagtagc gattattata tattggttgc catttctaaa gtttagatta
    10021 gttgtattat tatctataat atcaatagta gccaaacctt tattttttta tatgctaaat
    10081 atattagggg tgtatacctc ttatcttgat ggcaagatgg atattgaagg tgggaaatat
    10141 actcaattaa tatacttttt gttgtttatt atttgttttg ttttgggaag taaaaacata
    10201 gataaaaaca agtgtaattt atttaatgtt ttattgttaa gttttgtttt cgtatctttt
    10261 ttaggagctc atttaggcgg gagaatagcg ttttatttta atatatatta ttgtttgttg
    10321 attcctaaag tggttaaagg attggatggg caactaagag agcaagtgaa gcttctttct
    10381 tattttctat gtatttctta tttcttattg tacctattcg ttccattcat aaaaggtgta
    10441 ccctcatatt atatcccata taagtttata tttttcaaat agtaaaatgt tgatatctat
    10501 aattgtccct tgttataatt ctgaaagata tttgtctgat tgtttattgt ctatattgaa
    10561 tcaaacctat gttaattggg aggtgatttg tatagatgat ggaagtcaag ataatacatt
    10621 atctatttta aatcattacg ctacattgga tgagcgtttt aaaattattt ctcagtctaa
    10681 tgcaggagtg tctgtcgcaa gaaataaggc tctatcccag tgtcaaggag agtatatttg
    10741 ctttgttgat agtgatgacc tgatagaacc taattttttg ataacacttt tacagcttat
    10801 aagtcatcag gctgatttgg caatctgtgg ttttactcgt tctatggttt tctgtatgga
    10861 tgatgctcaa ggatatatag aaatgagtgg taaacgttgt atagaaagaa ttattctaga
    10921 taaaagtttc aatcctcaga tttgttgtat gttatttcga cataatatta taaaagagaa
    10981 acaattagaa tttgtgatag ggtgtactcg tggtgaagat cgtgaattta tattgaaata
    11041 tttagtttat tctaataagg tttgttatac aaacaatctt ctttatcact atcgtgtaaa
    11101 tgatcagtca gccatggcaa tcttttctat taaaagtttg acaagtatag aagcttcaca
    11161 acgcacggtc aactactata aaaaagtgaa ttattctgtt agagggcttg aatttgaatt
    11221 ttcacgtaca ttgtggaaat tcatgatttt agctattttg tctgggcaaa atgatttata
    11281 tcaaatcatt cgagaaaagt atgatctaaa aagacaaatg gaacatcttt attctcatcc
    11341 aggactatcc gaaaaactta cagcgagatt gtttgtttgg aatgaggcac tttttaaatg
    11401 ggtattttct attattagat atctatataa aaaaagatgg agatgaataa acgaaataga
    11461 ttatctgaac aagaaataaa aaaagtagaa cttgacgctt tattgtatat tcggaaaatt
    11521 tgtcagcaat atcatcttcg ctattattta gcttggggta ctttgttggg agccgttagg
    11581 cataaaggat ttattccttg ggatgatgat attgatataa tgatgccacg ttcagattat
    11641 gagcgattat tggagttagt tccttccttg agacatagtt attataaaat cttaagtaat
    11701 ccaaagaatg aggattatta ttatactcat gcaaaaatga tagatactcg tactttgtgt
    11761 gtggaaaatg atttgcaaac tattcaaaat atggggattt gggttgatat tttcccctta
    11821 g
//
