LOCUS       c00057_gnlPro..        16588 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JIDIIJKE_57.
ACCESSION   c00057_gnlPro..
VERSION     c00057_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 14:28:13
            Original ID  :: gnl|Prokka|JIDIIJKE_57
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16588
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16588
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3168:6726](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3169..6726
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16588
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16588
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(596..1750)
                     /locus_tag="ctg57_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDWKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1930..3135
                     /locus_tag="ctg57_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             3169..6726
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6851..7039
                     /locus_tag="ctg57_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(7050..7910)
                     /locus_tag="ctg57_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7938..8768)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg57_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8765..9991)
                     /locus_tag="ctg57_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKEEREKKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10465..11751
                     /locus_tag="ctg57_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFMRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFVAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVAMGIVLLTLPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFHKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11714..12046)
                     /locus_tag="ctg57_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12074..14827)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 63.7; E-value: 6.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg57_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.1e-20, bitscore:
                     63.7, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFCLTGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNTKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGRIAVRLSSLCKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGTISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKSSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFTKCYKEQFGESPTDFLKRKG"
     CDS             complement(15160..16386)
                     /locus_tag="ctg57_11"
                     /transl_table=11
                     /translation="MFFSLIVPLFLSLFYKPIAYLCGRSLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 cagggttagt aatatttcta gtcaacacat agcagctatt agagataaac aagtcaacca
       61 ttattaggga agtacacacc aattccaatt tagcagtatc ttcaaagagt ttccattgct
      121 tgaaaccaga gtttcatcgg tgtgaaactg tagtttcatc ggtgagaaac tagagtttca
      181 tacgcttgaa actttagttc caaacgctcg aaactatctg aaactactgt tgatttgatt
      241 gacttaaccg catgttccaa tcacattgaa cgcatcagct acttcaatag tactgctctc
      301 tctgaaaaca ttaaatcata tatcagtcaa taatacataa attatcagtc cttaatactt
      361 gatttctcaa ttattaatat ctgagaaatc aaacgttaac agttgagata tcagatatta
      421 acatcctgta aatcaaagaa taacacagta aaaacggtat ttatcaggac gatgcagagt
      481 gagagcaagt ccttgctctc actctgctac cactggatct ctaacagcta aaacatcgat
      541 gaataaaggg atacagacga actgttagag catgagagca aaagcactat ctttttcact
      601 gggggagagt aagcaaaaga aacgcacgat accggctttg aggcgtcacc ggtactaacg
      661 gcaaatatcc ggcacacacc cgattattct ctacggacaa agggaacgaa gccgacatct
      721 gccgatgttc ctccaaagcc tgaccggcta aaggataata atcaatccga aaaactcctt
      781 ccgcatccgc agccaaataa cgatccgtca agagccatgc caccaccccc atattcattc
      841 gcagattaat ttcgacacaa ggatgaatcc ggtaaacagg cgcttcatcc ggaaaatgac
      901 aaatcatcat atccactccc aagtatccat gataaaagcc accgaacaaa gctgacaatt
      961 cttcttccaa acgagtccgc agcctgataa attcttcttg tggcacataa gccgatagtt
     1021 tctgcagaat cttctcgtca gacagcaagt cattccctgc atacatccca ctcccacccg
     1081 tgtggaagac cgaatatccg gcaaaaacaa cccttcctct cccgtcagca taaaactcca
     1141 tagcgaaatc ttccacctta ttatatatag gttcgcctac caccccaccc tgagaagcag
     1201 cgacacgggc acaccaaccg gaaataaaag tagtaaatat gcctttacac caattcaatc
     1261 ctttcccgct tccggaaagc ggagctttta acaagcacgc ttcccgccct tcgacgaacg
     1321 cactgcactc cgccaaagta ctcaaataaa aagattctcc acagaagtat tcattcaacc
     1381 gcaacccagg caacaacttt accgcctgca gacgatgcga atgctctctc agaatattca
     1441 tataatccgc agaaggcagc tccgtctgac ctgcccccaa tgtcatcaaa cgcttccgca
     1501 aagcagggtc ccaaccccac ggagagaact tccagtcttt accgtcagcc acttccggtt
     1561 ccgtcaacaa ggccacatcc atgcccaaaa gttcactctt tgttttcagg aagtccgcat
     1621 tataagcaga cggtgcaagc accgcacttc ccgcttcggc ataccacata ggaagcaacg
     1681 ccaggtcact cgccatctgt cgggcggaag ccggcgccat atagttcgtc tcaccgcttg
     1741 ccaacgccat atcatgctcc ggattgaata tataaacagg tcttttcgtc atgtcaaaga
     1801 tggattcaac acattattct gcaaatatat acaggaaata atcaggaact tacacaataa
     1861 agagaaactt ataaattaaa gcacattttt gctatctcta ctttgcaaat cctaaaaaaa
     1921 gcactatatt tgccagccga aaaacaaaga aacgaaatgg aatcattcta tcgcacacac
     1981 gcctacctcg ttgagcacac caatgccccc gttcgccgcg atcttatgga cgagatcgac
     2041 tggagtgacc gtctgattgg tatcaaaggg acacgtggcg taggaaaaac cactttcctc
     2101 ctgcagtacg ccaaagagaa attcggcacc gaccgttcct gtctgttcat caatatgaac
     2161 aacttttatt tctccggtca cagccttgtt gacttcgcca acgagtttca gaaacgtggc
     2221 ggaaaagtac tgctgatcga ccaggtgttc aaacatcccg aatggagcaa agagctacga
     2281 atgtgctatg accgtttccc cagcctgaag attgtcttca ccggttcttc cgtcatgcga
     2341 ctcaaagagg aaaacctcga attgcgtgac attgcgaaaa gttataacct gcgcggattc
     2401 tctttccgtg aatttctgaa cctgcagaca ggaatgaaat tccgggcata cagcctcgaa
     2461 gaaatcctca gtacacatga acagatagcc aaaggagtac tttccaaagt acgaccgctg
     2521 gattattttc aggattacct gcatcatggt ttctaccctt tcttccttga aaaacgtaat
     2581 ttctcggaga atctgctgaa aacaatgaac atgatggtag aagtggatat cttgctgatc
     2641 aaacaaattg agctgaaata tctttcaaag ataaaaaaat tactatattt gttggctgtg
     2701 gacggaccga aagctccgaa cgtgagccaa ctggcaagtg acgtacagac atcccgcgct
     2761 acggtaatga actatatcaa gtatctggca gacgcgcgtc tgattaatct ggtttacccg
     2821 aaaggagaag aattcccaaa gaaaccgtca aagattatga tgcacaactc taacctgatg
     2881 tactccattt atccggtgaa agtggaagaa caggatgtac tcgacacgtt cttcgttaac
     2941 actttatgga aagaccataa ggtacataaa ggagataaaa acgtctcttt catggtagac
     3001 gaagtgatgc cgttcaaaat ttgtgcggaa ggtacaaaaa taaagaataa cccggacgtg
     3061 acgtatgcgt tgcaaaaggc tgagataggc cgcggcaacc aaatacctct ttggatgttc
     3121 ggattcttat actaaaaaga tttatttact taaatattta atttagttat gactaaacag
     3181 aagaaattca tcacatgtga tggtaaccaa gctgcagcac atatctcgta tatgttctct
     3241 gaagtagcag ctatctaccc catcactcct tcttcgacta tggctgagta cgtagacgaa
     3301 tgggctgccg caggacgtaa gaacatcttc ggcgaaacag tattggtaca ggaaatgcaa
     3361 tctgaaggtg gtgctgccgg tgcagttcac ggttctcttc aggctggtgc attgactact
     3421 acttacactg cttctcaggg tcttcttttg atgatcccta acatgtacaa gattgccggt
     3481 gaattcttgc cttgtgtatt ccacgtttct gctcgtacac tggcttctca cgcattgtgt
     3541 atcttcggtg accatcagga cgtaatgtca gctcgtcaaa ccggcttcgc tatgttggca
     3601 gaaggttctg tacaggaagt tatggatttg gcaggtgttg ctcatctggc tactatcaaa
     3661 tcacgcgttc cgttcatgaa cttcttcgat ggtttccgta cttctcacga aatccagaag
     3721 atcgaaatgt tggaaaacga cgacctcgct ccgctgatcg accaggaagc tttggctgaa
     3781 ttccgtgccc gtgcactgaa tccgatgaag ccggttgccc gtggtatggc tgaaaacccc
     3841 gaccacttct tccaacatcg tgaatcatgc aataactact atgaagcagt tcctgctatc
     3901 gtagaagaat acatgaacga aatttccaag atcacaggcc gcaaatacgg tttgttcgat
     3961 tactacggtg cagaagatgc agaacgcgta attatcgcaa tgggttctgt aactgaagct
     4021 gcccgcgaag ctatcgacca cttggtagca aacggcgaaa aagtaggtat ggttgccgta
     4081 cacttgtatc gtccgttctc tgctaaacac ttcctggctg ctgtacccaa gactgcaaag
     4141 agcatcgcag tgcttgaccg tacaaaagaa ccgggtgcta acggcgaacc tctttacctt
     4201 gacgttaaag actgcttcta tggcgcagaa aatgctcctg ttatcgttgg cggtcgctac
     4261 ggtctgggtt caaaagatac aactccggca cagatcatct ctgtattcga aaacttggct
     4321 atgccaatgc cgaagaacca cttcactatc ggtatcgtag acgacgttac gttcacttct
     4381 cttcctcaga aagaagaaat cgctctgggc ggtgaaggta tgttcgaagc taaattctac
     4441 ggtctgggtg ctgacggcac agtaggtgcc aacaagaact ctgttaagat tatcggtgac
     4501 aacaccgaca aacactgtca ggcttacttc tcttacgact ccaagaagtc gggtggtttc
     4561 acttgttctc acctgcgttt cggtgatact ccgatccgtt ctacttactt ggtaaatact
     4621 ccgaacttcg ttgcttgtca cgttcaggct tacctgcaca tgtacgacgt aacacgtggt
     4681 ttgcgtaaga acggttcttt cttgctgaat accatctggg aaggcgaaga actggctaag
     4741 aacctgccta acaaggtgaa gaaatacttt gcacagaaca acatctctgt atactatatc
     4801 aacgcaactc agattgcaat ggaaattggt ttgggcaacc gtaccaatac aatccttcag
     4861 tctgcattct tccgtatcac aggcgtaatc cctgtagatc aagctgttga acagatgaag
     4921 aaattcatcg ttaagtctta cggcaagaag ggtgaagacg ttgttaacaa gaactacgct
     4981 gctgtagacc gcggtggtga atacaagact ctgactgtcg atcctgcttg ggctaacctg
     5041 ccggatgatg caaaagcaga aaacaatgat cctgctttca tcaacgaagt agttcgtccg
     5101 atcaatgcac aggacggtga cttgctgccg gtatctgcat tcaagggtat cgaagacggt
     5161 acttggtatc aaggtacttc caaatacgaa aaacgtggtg tagctgcatt cgttcccgaa
     5221 tggaatgctg aaaactgtat tcagtgtaac aagtgtgctt acgtttgtcc tcacgcttct
     5281 atccgtccgt tcgtactcga tgctgaagag cagaagggtg ctaagttcga gcaactgaaa
     5341 gctgtaggta aagcattcga tggtatgaca ttccgtattc aggtagacgt tctcgattgt
     5401 ctgggttgcg gtaactgtgc cgacatctgt ccgggtaatc cgaagaaggg tggcaaggca
     5461 ttgaccatga aacaccttga aagccagttg gccgaagctg ataactggac ttactgcgct
     5521 gaaaacgtga agagcaaaca acacctggta gacatcaagg ctaacgtgaa gaactctcag
     5581 ttcgcaactc cgttgtttga gttctcaggc gcttgctccg gttgtggtga aactccgtac
     5641 gtgaaactga tttctcagtt gttcggtgac cgtgaaatgg ttgctaacgc tacaggatgt
     5701 tcttctatct actccggttc agttccttct actccgtaca ctatgaacga aaagggtcac
     5761 ggtcctgcat gggctaactc cttgttcgaa gacttctgtg aatttggtct gggtatggaa
     5821 ctggctaacg aaaagatgcg tgcccgtctg gtgaaagtaa tgaacgaagc tatcgcttct
     5881 gattgctgcc cggctgaata caaagaagta tttgctgaat ggatcaacaa tatgctggat
     5941 gcagaaaaga ctaaggaact ggccgaaaag atcattccga tggtagaagc tgctaaagat
     6001 aaatgcaacc actgcaagca aatcgctgat ctgcaacaat atcttgttaa acgcagccaa
     6061 tggatcatcg gtggtgacgg tgcttcttat gatatcggtt acggtggtct tgaccatgta
     6121 atcgcttccg gtaaggacgt taacatcctt gtattggata ctgaggttta ctctaacaca
     6181 ggtggtcagt cttctaaagc tactccggta ggcgctatcg ctaagtttgc tgctgcaggt
     6241 aagcgtgtac gtaagaaaga cctcggtctg atggctacta cttacggtta tgtatatgtt
     6301 gctcagattg ctatgggtgc tgaccaggct cagactctga aagctatccg tgaagctgaa
     6361 gcatatccgg gaccatcact gatcatcgct tacgctccat gtatcaacca cggtctgaaa
     6421 gccggtatgg gtaagagcca ggaagaagaa gaaaaggctg ttaagtgcgg ttactggcac
     6481 ttgtggcgtt acaaccctgc tttggaagaa gaaggcaaga atccgttcca actggatagc
     6541 aaagaaccta actgggaaga cttccaaggt ttcttgaagg gtgaagttcg ttacgcttct
     6601 gtaatgaaac aatatcctgc tgaagctgaa gaactgttta aagctgctga agaaaacgct
     6661 aaatggcgtt acaacagcta caaacgtctt gccagagaaa actggggagc tgatacagct
     6721 gaataataag tagaaatact ttgtacataa taaaaggcag gaatcctgga aacagattcc
     6781 tgcctttttt gtttatatct tagaagtaac gattacttct cacgaagata ttcattaaaa
     6841 ctctaaagat atgatcggat ttgttatttg gattatcggt ttgatactga ctttcagagc
     6901 tgccatagag atttggaata taaatgcggc tgtagagaaa agacttatag cgattgtatt
     6961 aatcgttctt accagctggc tgggactact tttctactac ttctatggta aagaaagaat
     7021 ggcgggatgg ttgaagtagt gtttgcatat caatctttct caggaatcca actgttcacc
     7081 agttcctgat gttcttccat ccattgacgg gcagcctgtc tttccgttgt ctgcgcctct
     7141 tccagagcag tcattaagga gctgatttcc gcatctgtca gacgaatgtt gcccaaaagt
     7201 tcggcagcaa aagggtcttt ctcgctaaaa cctttccatg ctatggtatg aatggattcc
     7261 gtatttccat atatcagctt cgggtcctga agaactttca gcttgaaacg gtcgaacatc
     7321 cagtgaggcg tccatcccgt cacgacaatc cagtctttct tatcaatcgc tttctttagg
     7381 gaagcagtca tggcaggtcc gctcgaagtc atcagtttat aatccaatcc atagtctttg
     7441 atggcctgat cggtagcttt cataataccg gctccggcat caataccgac aatctgaccg
     7501 gagaaacgtt ccttttccgc gttcagttct tcgattgagt tgatcgtaac gtaatccgga
     7561 accaccagcc cgatacgggc accatcataa atatccccga taacttcgag tttatccccg
     7621 tattgtttca tataatcttc catagtgaca ggcatccaga catccataaa tacgtctgct
     7681 ttcttacggg agatagaggt aaatataggt gcaaggtcgg cattcagcaa ctttacatcg
     7741 tacccctgat cttcaaaaat cgctttggca aggtttgtca ttgcaatacc ttccgaccag
     7801 ttggcataag cgatacttat cttcttactc tttccgttgt ctccgcagga aacgaaggtt
     7861 aagagtatgc cggcaataaa cattgccgca atcattttta tcttattcat tgattattcc
     7921 tttctttggt gtgattctta tttcttttta ctttttctgt tatctgccat accctgagtg
     7981 atgcggtcca gcacgatcgc caatatcacg actgcgatac cgccttcaaa tccgagtccg
     8041 attttcattt gggtgatacc tttcagcacg atttctccca atcctccggc agaaatcatg
     8101 gcagcaatca ctaccatcga aagtgacatc atgatcgtct ggttgattcc cgtcagaata
     8161 gtaggcaacg ccaaaggcaa ttgcacctta taaagaagct gccagggagt agctccaaaa
     8221 gagcgggagg cttctactac gtttttagga acctgacgaa tgcccagacc ggtcagacga
     8281 accacaggag gcattgcaaa gatgatggtg gcaaaagctc ccggcacagt tcccaatccg
     8341 aagaatagaa cggcaggaat cagatagaca aaggcaggca ttgtctgcat aaagtcgagg
     8401 acagggcgca ttatcttgtt acaacgatca ctgttggcag tccagattcc cagcggaacg
     8461 cctaaaagca atgccagaca agtggaagaa agtactaacg ccaatgtctg catcgtttct
     8521 tcccaaaagc ccatgccgta aataagcaat aagcccaaga gggtaaatac ggctgtcccc
     8581 ttacccgact taaaccaggc gagcgcagcc agcactgcaa ttgtgatata aaaaggtatt
     8641 ccaaacagta cgtgctgaaa accgtctatg aatcctccga tccccatgct gagagcatca
     8701 aaaaaggaag caaaatgttc tgtgagccaa ttaatggcag tttctatata ttgtccgata
     8761 tttatcataa ttctattgcg ttttgaatga tttcattaat ttcttcttta tcttttcccg
     8821 ttacttcgat gatcaatgag gaaagtggca ctacgccttc aaactcccga ttctcattta
     8881 cgacccagat tggcgagttc gtttttgtca tcaacggaag aatatcttcc agcaccgtat
     8941 cacccagcac tgaatgaact tcatgcctta ctacggactc gatggagcgg atttgctctt
     9001 ttcgtagttt cagcaagtca ttcaaccgca cctctcctac taacagatta ttggaatcga
     9061 ctaccggaag aacggtcaga ttccgttcgc gcatcttacg gatcagcacc tccgggcctt
     9121 ctttcttcaa acgtgccact atgggtttat ctaccataac agaggaagct gttataatct
     9181 tgcttcgatc tacattctcc acaaatcgtt ctacataagc gttggcaggt tcggtcagga
     9241 tttcttccga tgtaccgatt tgtacaattt ctccatcctt catgatagca atccggtcac
     9301 ccaatttaat cgcttcactc aggtcgtgag taataaagac aatcgttttt ttcatcttcg
     9361 actgcaaagt cagcagttca tcctgcatct gcacacggat caaaggatcg agtgccgaga
     9421 aggcctcatc catcaacagg acttcgggat tattggccaa agcccgcgcc agcccgacac
     9481 gctgctgcat cccacccgac agttcactta ccatctgatt ctcgtagcct ttcagcccca
     9541 ccagttgcat actttccatc gctttcttct cccgttcttc ctttttaact ccctgtagtt
     9601 cgagtccgaa agctatatta tgcaagacag aacggtgagg aagcagaccg aagttctgaa
     9661 agaccatagc cagttctttc cggcgaatct gcaacagttc tttatccgac actttggcta
     9721 tgtctgttcc attgataatc acttctccgg aagtagggcg tatcaaacgg ttgatgcagc
     9781 ggagtaaagt ggactttcca ctaccggaca accccataat gacgaatatt tcgccttcat
     9841 taatggaaag attcgcatct ttcaccgcaa ccgtacatcc ggtcgctttc aatatttcac
     9901 ttttagtttt accttctttc aacatcttca aagccttctg cttctcattg ccaaaaacca
     9961 gatagagatc tttaatttct attttactca tacaataaaa tggtttaggt tattaaaata
    10021 atatacacag caagacaaga acaaacgata acaggaatct ttctttatat cgtataaagt
    10081 tctgatttaa atacgggaca aataacaatg aatcccgaaa taattaataa aatgattatt
    10141 gacagactga gtaattaaaa aaggaataga atttgataag ataatccttt caacgaatag
    10201 caaaaaaata gcatttttat gtataaaaac agtctgttcc agtatcttgc tggcacaaag
    10261 atacaaaaaa cagattaaac atgcaaatta tattcaaaat ccggggcata cagaggactt
    10321 tatttgtaat gatatggaaa gtttccgggt aatattcccc tatcactcag caaaatagaa
    10381 caaaccagca gataaatata aaataagttt gaatatttca cctaaacacc gtatatttgg
    10441 cgtcaataac taaactagat ttatatgttc aacagggcta ttacaatttt cctggggaag
    10501 gataattgtc attacacaac aaaagaaaaa caaacaggta ctgccacact agacgacaaa
    10561 agccaagtac agttccttag taaaaagaac cccaaaatgc cgtttttcta tagtcggcgg
    10621 aatctctaca tgataggttt cctgctcgct tttatagtga ctctgctcga atttatgcga
    10681 ggacggcatc aaaactttat ggtcttctca gacgctactc aattcttctg gcaaggcatc
    10741 agcccataca caaccgaatt tgtagaagct cacggacgct acttccttta ttctcctgtt
    10801 ttcacggtat tgttcgctcc gtttgcgtat ctgcctgcat ggctgggacc tttcgcgtgg
    10861 aatctattca attattcatt gttctttgtg gcgatcttca cgctgcccca acaattcacc
    10921 cagcaacaga aatgccgtat gttccttttt ctgttactga ttttaggaca aagtttactt
    10981 tcatttcagt ataacataac ggtagcctat ttattcttat tcgcctatac gttattggaa
    11041 aaagaccgtg gatttctggc tgttctgtta atcatgattt cgggatgtac caaagtatat
    11101 ggaattttcg aactggcatt gttgctgtgc tatcctcacg tatggcgtaa ctttggctat
    11161 gccgttgcaa tgggcattgt attgcttacg ttaccgttaa tcaaaatagc tcctgcagat
    11221 ttgctcccct attatgaaga atggtgccat agtcttgctg ttcatcaatc cgccggagct
    11281 tatgattcat ttttctatgc ccgccccatt gcagcatgga cattgccaca cttccgtgca
    11341 cttcagatag gaatgctcgg tctactgact ctgctctttt tggggaattt ccacaaatgg
    11401 tcgtcttttg ccttccgtgc ccaagctttg ggcattctca tgggctgggt agtattactg
    11461 agtgactccg ccgagaaaca tacctatatt atcgcattgg caggtttcat gctctggtat
    11521 tggagcaggc caacacgtac cgcaacagac aagattctat tttggtgctg ttttgtgctg
    11581 ttatgcatcg ttcctatcga catattcgtc cctgttccca tcagagattt cattaccagg
    11641 accttatggc ttcatgtatg ggttttcttt attgtatgga tacggatgat atggcttacc
    11701 ttccttgcat ccttcattca tccacgtgcc acaaatgttc tttcagatta acgcatccgt
    11761 tagctttgaa agaaacttct tctgccagca agagttgttt ttgttccacc caaccgggta
    11821 ccagccttcc ggtggaattt acaactctat ggcaaggaat ggataattca tccggcactt
    11881 ctttcaatgc acgccccacc atccgcgaac attggggggc acccaaaagc aaagcaatac
    11941 ctccataggt agatactttt cccacaggta tctgggatac gacttcgtac acttccttcc
    12001 gaaaggattc ggaaaaactc tctttatcta ctttataatc tttcatatat ccctctttac
    12061 gatctcaatg aaatcatcct ttccttttca ggaagtctgt cgggctctct ccgaactgct
    12121 ctttatagca cttggtgaaa taagaaggtg aactgaaacc gacttcataa ccaatctccg
    12181 ctacggtcat gtccgaagaa gcaagcaaag aagctgcctt cttcaaacgg gcgatacgga
    12241 gcaattcatt cggagagtag ttagtcaacg atttaatctt gcggtaaagc tgcacacggc
    12301 ttagtcccat atccttgccc aagtcctcca cattcaaacc ggagtctccc attttctctt
    12361 caatcaatga cttgaatctt tctacaaaat ccttgtccat atcgcaaaca tcttccttcg
    12421 ccaatgtctg cccgtcacca aagaactgtt tcagacgacg gtgagaatcg atcaggttgc
    12481 ggacacgtgc cagcaacagt tgtgaactga acggctttga aatataagaa tcggcaccac
    12541 cgtcatatcc ctgaatacgc tgttcgtcca gtgaacacgc cgtcagcaga ataaccggaa
    12601 tatgacaggt ctgtaactca cttttcagcc ggcggcaaca ttcaatgcca tcaatgcccg
    12661 gcatcatcac atcggaaata atcaggtcag gaacatactt catagcctta cggattcctt
    12721 cggagccgtc tgccgcttca atcaccgtat agtctgtatg caacagcgta tggacatacg
    12781 aacggatatc ctcattatca tcaataatca gtacggacga tttggaagag tcatatcctt
    12841 tttccagttc ttcctcttcc gccaatagaa catctgttgt acgggaatcc gcagaaacaa
    12901 gggtggtatc cggttcggca gcaacagcct cgcaagactg tacaggcagt tcaacggtaa
    12961 agaccgtacc ctgtttctca tcgctctcta cagagatcgt accaccatgc atttctacga
    13021 aggcttttac caatgccagt ccgattcccg aaccggtatg gtgcatatcg atcttataga
    13081 aacggtcgaa tacattgcgg atatgttcgg cagaaatcat agaaccggta tttgccaccg
    13141 tgaaacgtat ccatcgcttg tcctctttac aaagggaaga cagacgaacg gcaattcttc
    13201 cattttccgg tgtaaactta aaggcattgg acaggagatt gaaataaata cgttccagct
    13261 tctccatgtc tgccagtgta tgataatccg tatccggcat actatcaaaa gaaaaatgga
    13321 tatgcttctt acgggctgcc gcctgaaaag actcattcca tccttcgaaa gaagaaagga
    13381 catccaccgt aaccggagta tattccatct tgccattttc atatttacgg aaatccagaa
    13441 tctgattgac cagacgcaga agaatgttca cattccgctg aatcagcatg agcatccggt
    13501 gctgatctcc gctcagtgtc ttgtccgcca acaaatgttc taccggatcg gcaaccaatg
    13561 tcaacggagt acggaagtcg tgagaaatat tggtgaagaa taccagcttg gcatgagtag
    13621 cttcttccag ttgatgagaa agttgtatca attggtcacg ctgttcttcc agtttgtcac
    13681 gttgctcttc caattgttgc ttctgcttaa aaagctcttt attcaagcga ttctttgagc
    13741 ggagtgattt ataaacgacc aataataagc cggctaccaa taaaaggata atcagactgc
    13801 cgtataaaac gacctgttgt gtagctacct gagagagata gccaccgata cgtccgttga
    13861 gcgtttcaat ctttttgtcg agttcggaaa tgtgtgtggt ctgcaactgc atgacgtgtg
    13921 cgttggtacg gtccacaaca gcggtattca tcaccgtttc tttgggatag ggtttcttct
    13981 ccagaatatc catagccagt tgcagtacct tatcaccatt ggtcggatag ataaaggtag
    14041 catccagcac actgtccaga accagctcca gcccgtttcc cttacccggc aaggcatcta
    14101 tgccgacaaa aatcatttcc ttctcccgcc ctgccatctt tgctgcctga taggcacccg
    14161 gagcgatacg atcattatgg gcatacacag catcaatctt aggatgcctc cgaagcatac
    14221 tatccatttc tatctctgcc ggaccacgtt cccaagcagc atccgcttta tcaatcagct
    14281 ttatatccgg gaatttactg atggcagcca taaatccctg atgccgttcc attgcaggag
    14341 tcgaaccgct caatcctgtc agttctacta tatttccctt ccctttcaga ctggaggcaa
    14401 tatagtttcc taccgaacga ccgatttcat aattatcggc tccgatatag gcagtatatt
    14461 tatccgaaag aatcttccgg tctacaagaa taacggggat gcctttctga taagcttctt
    14521 ctacaatcgg agtcatagga gcagcttcgt tagcggaaat aatcagcaga tcgactcctt
    14581 cgtccataaa ataatggaca tcttccgcct gcttagtgtt atcatcccct gccgaacgga
    14641 tttccaccga aacaccatta taaaacatcg cttcccgaag aatctcatca ttcatcttat
    14701 gtcgccatga atcatcgctg cattgagcca ccccaatacg aaaacggggt gtatcctgcc
    14761 ggcaagccgt catcccggtt aaacaaaaca gcaccagcat ccacttcaga tatctcatcg
    14821 tcttcatcca tctcatcatt tcgtagttct ttctgtaatc caattaagaa caaaaataag
    14881 aaataatact gtaaagttct ctaacttcag ctatttatta ttctaaaaag aaggaaagca
    14941 gtcctctttc agaccatcgg aaagtattaa caaaagtata aagcgtaaaa caaacactta
    15001 atcaatgtta taaaacatag cgttttactt ggataatttg cagatttcac agaagtccgt
    15061 atctttgtac tgtgtttttc atagtattag atttaaggtt aacaaaggtt ggagcaaggc
    15121 gttgctcctt tttttatgcc ctgacctttc atctaccggt tagttttcat cccattcctt
    15181 ttccagttta ccatcaatag tgtagcgttt ccatcgtcct acacggcgac cattcttata
    15241 ttccccacat tcacgaagct ggtcattctt tacataacga gcttcgaacg gtccgttctg
    15301 ccttccgttc acataggtag aagtttccca ataatcaaag cggttgctca ctatcagccg
    15361 tcgttccttg ccatgcaatc tgccggcctg ataggtagct tcatatctca attcaccatt
    15421 ttccaaatta tattcacggt ataaaccgtc tttacgatcg ttcttcatat aatattcttt
    15481 ctgccttacc ccacttccgt tggcaaatga gacatggagt ccatcttctt ttccatccag
    15541 ataggtttca atcatcagcg tatcgccgct ttcagcaaaa gtagtccaac gaccattctt
    15601 ctttccattc ttataactac ccagtatacg tggcgagcca aacgtaaaca cggacgaata
    15661 ttcaccgtcc tgaaaacctt cttcattgaa ataaacggtc tcatacaaat catatgtacc
    15721 tttcagaaaa gtatactgtt tgcctacctg cttcccgtcc ttgtaattat gctctttccg
    15781 caaagtaccg tcagattcgt acgacagttg cttcccgtgc tctttcccca tccggaagtt
    15841 tctttcactt tccacttttc cggtagtaaa gtaacttttg ctcgtaccgt ccagcttacc
    15901 ttccttatag gacttttctt ctttcagctt accgtcaaac ttggagttaa tcttgaagag
    15961 accatccttc cgtccttctt tataacttcc ttctgttatt aatatattgt ctacatattc
    16021 tttgtatccg ccatcataga aaccatcttt aaaagatgcc agcacatagg cggaatgata
    16081 accatctatg atgcgatgtt cgccattcaa tgctttttcc gttttcagtt cctgaaacaa
    16141 cagtctgcca tcgcctacat tgacaacgga tacctgatcg atcttatatt ccttttgcgc
    16201 aaacaaagga agagcaagat ataaaaacaa aaatacgttc cagctttttg atctgaggaa
    16261 gttcgaaatg tgtttcataa agtagttttc tctttttgat ttattattta aagacctgcc
    16321 gcaaagatag gcaatcggct tataaaacaa ggaaagaaag agggggacaa ttagagaaaa
    16381 gaacatctgt tattatcatt ctaataatta acagattaag tagtaaatca aaacacaggg
    16441 aagggggaca tttactgaaa taagaaacag aaaagaaggt gtgtcaaaag caactaaatt
    16501 cccctccttc aggaagctac cctttataca caagtcttag ctgattaact catacagttc
    16561 aaactgtgta ttaaatctat ccagtcca
//
