LOCUS       c00058_gnlPro..        16655 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IBEFILGH_58.
ACCESSION   c00058_gnlPro..
VERSION     c00058_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 14:16:00
            Original ID  :: gnl|Prokka|IBEFILGH_58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16655
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16655
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9896:13454](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(9897..13454)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16655
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16655
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             238..1464
                     /locus_tag="ctg58_1"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
     CDS             1797..4550
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg58_2"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             4578..4910
                     /locus_tag="ctg58_3"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(4873..6159)
                     /locus_tag="ctg58_4"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPIPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             6632..7858
                     /locus_tag="ctg58_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7855..8685
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg58_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             8713..9573
                     /locus_tag="ctg58_7"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(9584..9772)
                     /locus_tag="ctg58_8"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(9897..13454)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_9"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             complement(13488..14693)
                     /locus_tag="ctg58_10"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             14873..16027
                     /locus_tag="ctg58_11"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
ORIGIN
        1 ttagttcact gcaactctac ttttcaaata tacacttata ttttgttgtg atatttaata
       61 ctgcaaatgt aaatgtgtca aaagtcaaaa gtaactaaac tctcctcctt cctgaaggag
      121 gggaatttag ttgcttttga cacatcttct tttctgtttc ttatttcagt aaatgtcccc
      181 cttccctgtg ttttgattta ctacttaatc tgttaattat tagaatgata ataacagatg
      241 ttcttttttc taattgtccc cctctttctt gccttgtttt ataagccgat tgcctatctt
      301 tgcggcaggt ttttaaataa taaatcaaaa agagaaaact actttatgaa acacatttcg
      361 aacttcctca gatcaaaaag ctggaacgta tttttgtttt tatatcttgc tcttcctttg
      421 tttgcgcaaa aggaatataa gatcgatcag gtatctgttg ttaatgtagg cgatggcaga
      481 ctgttgtttc aggaactgaa aacggaaaaa gcattgaatg gcgaacatcg catcatagat
      541 ggttatcatt ccgcctatgt gctggcatct tttaaagatg gtttttatga tggcggatac
      601 aaagaatatg tggacaatat attaataacg gaaggaagtt ataaagaagg gcggaaggat
      661 ggcctcttca agattaactc caagtttgac ggtaagctga aagaagaaaa gtcctataag
      721 gaaggtaagc tggacggtac gagcaaaagt tactttacta ccggaaaagt ggaaagtgaa
      781 agaaacttcc ggatggggaa agagcacggg aagcaactgt cgtacgaatc tgacggtact
      841 ttgcggaaag agcataatta caaggacggg aagcaggtag gcaaacagta tacttttctg
      901 aaaggtacat atgatttgta tgagaccgtt tatttcaatg aagaaggttt tcaggacggt
      961 gaatattcgt ccgtgtttac gtttggctcg ccacgtatac tgggtagtta taagaatgga
     1021 aagaagaatg gtcgttggac tacttttgct gaaagcggag atacgctgat gattgaaacc
     1081 tatctggatg gaaaagaaga tggactccat gtctcatttg ccaacggaag tggggtaagg
     1141 cagaaagaat attatatgaa gaacgatcgt aaagacggtt tataccgtga atataatttg
     1201 gaaaatggtg aattgagata tgaagctacc tatcaggccg gcagattgca tggcaaggaa
     1261 cgacggctga tagtgagcaa ccgctttgat tattgggaaa cttctaccta tgtgaacgga
     1321 aggcagaacg gaccgttcga agctcgttat gtaaagaatg accagcttcg tgaatgtggg
     1381 gaatataaga atggtcaccg tgtaggacga tggaaacgct acactattga tggtaaactg
     1441 gaaaaggaat gggatgaaaa ctaaccggta gatgaaaggt cagagcataa aaaaaggagc
     1501 aacgccttgc tccaaccttt gttaacctta aatctaatac tatgaaaaac acagtgcaaa
     1561 gatacggact tctgtgaaat ctgcaaatta tccaagtaaa acgctatgtt ttataacatt
     1621 gattaagtgt ttgttttacg ctttatactt ttgttaatac tttccgatgg tctgaaagag
     1681 gactgctttc cttcttttta gaataataaa tagctgaagt tagagaactt tacagtatta
     1741 tttcttattt ttgttcttaa ttggattaca gaaagaacta tgaaatgatg agatggatga
     1801 agacgatgag atatctgaag tggatgctgg tgctgtttgg tttaatcggg atgacggctt
     1861 gccggcagga tacaccccgt tttcgtattg gggtggctca atgcagcgat gattcatggc
     1921 gacataagat gaatgatgag attcttcggg aagcgatgtt ttataatggt gtttcggtgg
     1981 aaatccgttc ggcaggggat gataacagta agcaggcgga agatgtccat tattttatgg
     2041 acgaaggagt cgatctgctg attatttccg ctaacgaagc tgctcctatg actccgattg
     2101 tagaagaagc ttatcagaaa ggcatccccg ttattcttgt agaccggaag attctttcgg
     2161 ataaatatac tgcctatatc ggagccgata attatgaaat cggtcgttcg gtaggaaact
     2221 atattgcctc cagtctgaaa gggaagggaa atatagtaga actgacagga ttgagcggtt
     2281 cgactcctgc aatggaacgg catcagggat ttatggctgc catcagtaaa ttcccggata
     2341 taaagctgat tgataaagcg gatgctgcgt gggaacgtgg tccggcagag atagaaatgg
     2401 atagtatgct tcggaggcat cctaagattg atgctgtgta tgcccataat gaccgtatcg
     2461 ctccgggtgc ctatcaggca gcaaagatgg cagggcggga gaaggaaatg atttttgtcg
     2521 gcatagatgc cttgccgggt aagggaaacg gactggaact ggtactggac agtgtgctgg
     2581 atgccacctt tatctatccg accaatggcg ataaggtact gcaactggct atggacattc
     2641 tggagaagaa accctatccc aaagaaacgg tgatgaatac cgctgttgtg gaccgtacca
     2701 acgcacacgt catgcagttg cagaccacac acatttccga actcgacaaa aagattgaaa
     2761 cgctcaacgg acgtatcggt ggctatctct ctcaggtagc tacacaacag gtcgttttat
     2821 acggcagtct gattatcctt ttattggtag ccggcttatt attggtcgtt tataaatcac
     2881 tccgctctaa gaatcgcttg aataaagagc tttttaagca gaagcagcaa ttggaagagc
     2941 agcgtgacaa actggaagaa cagcgtgacc aattgataca gctctctcat caactggaag
     3001 aagctaccca tgccaagctg gtctttttca ccaatatttc tcacgacttc cgtactccgt
     3061 tgacattggt tgccgacccg gtagaacatt tgttggcgga caagacactg agcggagatc
     3121 agcaccggat gctcatgctg attcagcgga atgtgaacat tcttctgcgt ctggtcaatc
     3181 agattctgga tttccgtaaa tatgaaaacg gcaagatgga atatactccg gttacggtgg
     3241 atgtcctttc ttctttcgaa ggatggaatg agtcttttca ggcggcagcc cgtaagaagc
     3301 atatccattt ttcttttgat agtatgccgg atacggatta tcatacactg gcagacatgg
     3361 agaagctgga acgtatttat ttcaatcttc tgtccaatgc ctttaagttt acaccggaaa
     3421 acgggaaaat agccgtccgt ctgtcttccc ttagtaaaga ggacaagcga tggatacgtt
     3481 tcacggtggc aaataccggt tctatgattt ctgccgaaca tattcgcaat gtattcgacc
     3541 gtttctataa gatcgatatg caccataccg gttcgggaat cggactggca ttggtaaaag
     3601 ccttcgtaga aatgcacggt ggtatgatct ccgtagagag cgatgagaaa cagggcacgg
     3661 tctttaccgt tgaactgcct gtacagtctt gtgaggctgt tgctgccgaa ccggatacca
     3721 cccttgtttc tgcggattcc cgtacaacag atgttctatt ggcggaagag gaagaactgg
     3781 aaaaaggata tgactcttcc aaaccgtccg tactgattat tgatgataat gaggatatcc
     3841 gttcgtatgt ccatacgttg ttgcatacag actatacggt gattgaagcg gcagacggct
     3901 ccgaaggaat ccgtaaggct atgaagtatg ttccggacct gatcatttct gatgtgatga
     3961 tgccgggcat tgatggcatt gaatgttgcc gccggctgaa aagtgagtta cagacctgtc
     4021 atattccggt tattctgctg acagcgtgtt cactggacga acagcgtatt cagggatatg
     4081 acggtggtgc ggattcttat atttcaaagc cgttcagttc acagctgttg ctggcacgtg
     4141 tccgcaatct gatcgattct caccgtcgtc tgaaacagtt ctttggtgac gggcagacat
     4201 tggcaaaaga agatgtctgc gatatggaca aggattttgt agaaagattc aagtcattga
     4261 ttgaagagaa aatgggagac tccggtttga atgtggagga cttgggcaaa gacatgggac
     4321 taagccgtgt gcagctttat cgcaagatta aatcattgac taactactct ccgaatgaat
     4381 tgctccgtat cgcccgtttg aagaaggcag cttctttgct tgcttcttcg gacatgaccg
     4441 tagcggagat tggttatgaa gtcggtttca gttcaccttc ttatttcgcc aagtgctata
     4501 aagagcagtt tggagagagc ccgacagatt tcctgaaaag gaaaggatga tttcattgat
     4561 atcgtaaaga gggatatatg aaagattata aagtagataa agagagcttt tccgaatcct
     4621 ttcggaagga agtgtacgaa gtcgtatccc agatacctgt gggaaaagta tctacttatg
     4681 gaggtattgc tttgctgttg ggggcacccc aatgctcgcg gatggtggga cgtgcattga
     4741 aagaagtgcc ggatgaatta tccattccct gccatagagt tgtaaattcc accggaaggc
     4801 tggtgcccgg ttgggtggaa caaaaacaac tcttgctggc agaagaagtt tctttcaaag
     4861 ctaacggatg cgttaatctg aaagaacatt tgtggcacgt ggatgaatga aggatgcaag
     4921 gaaggtaagc catatcatcc gtatccatac aataaagaaa acccatacat gaagccataa
     4981 ggtcctggta atgaaatctc tgatgggtat agggacgaat atgtcgatag gaacgataca
     5041 taacagcaca aaacagcacc aaaatagaat cttgtctgtt gcggtacgtg ttggtctgct
     5101 ccaataccag agcatgaaac ctgccaatgc gataatatag gtatgcttct cggcggagtc
     5161 actcagtaat actacccagc ccatgagaat gcccaaagcc tgggcacgga aggcaaaaga
     5221 cgaccatttg cggaaattcc ccaaaaagag cagagtcagc aagccgagca ttcctatctg
     5281 aagtgcacgg aagtgtggca atgtccatgc tgcaatgggg cgggcataga aaaatgaatc
     5341 ataagctccg gcggactgat gaacagcaag actatggcac cattcttcat aataggggag
     5401 caaatctgca ggagctattt tgattaacgg taatgcaagc aatacaatgc ccattgtaac
     5461 ggcatagcca aagttacgcc atacgtgagg atagcacagc aacaatgcca gttcgaaaat
     5521 tccatatact ttggtacatc ccgaaatcat gattaacaga acagccagaa atccacggtc
     5581 tttttccaat aacgtatagg cgaataagaa taaataggct accgttatgt tatactgaaa
     5641 tgaaagtaaa ctttgtccta aaatcagtaa cagaaaaagg aacatacggc atttctgctg
     5701 ctgggtgaat tgttggggca gcgtgaagat cgccataaag aacagcgaat aattgaatag
     5761 attccacgcg aaaggtccca gccatgcagg cagatacgca aacggagcga acaataccgt
     5821 gaaaactgga gaataaagga agtagcgtcc gtgagcttct acaaattcag ttgtgtatgg
     5881 gctgatgcct tgccagaaga attgagtagc gtccgagaag accataaagt tttgatgccg
     5941 tcctcgtata aattcgagca gagtcactat aaaagcgagc aggaaaccta tcatgtagag
     6001 attccgccgg ctatagaaaa acggcatttt ggggttcttt ttactaagga actgtacttg
     6061 gcttttgtcg tctagtgtgg cagtacctgt ttgtttttct tttgttgtgt aatgacaatt
     6121 atccttcccc aggaaaattg taatagccct gttgaacata taaatctagt ttagttattg
     6181 acgccaaata tacggtgttt aagtgaaata ttcaaactta ttttatattt atctgccggt
     6241 ttgttctatt ttgctgagtg ataggggaat attacccgga aactttccat atcattacaa
     6301 ataaagccct ctgtatgccc cggattttga atataatttg tatgtttaat ccgttttttg
     6361 tatctttgtg ccagcaagat actggaacag gctgttttta tacataaaaa tgctattttt
     6421 tgctattcgt tgaaaggatt atcttatcaa attctattcc ttttttaatt actcagtctg
     6481 tcaataatca ttttattaat tatttcggga ttcattgtta tttgtccctt atttaaatca
     6541 gaactttata cgatataaag aaagattcct gttatcgttt gttcttgtct tgctgtgtat
     6601 attattttaa taacctaaac cattttattg tatgagtaaa atagaaatta aagatctcta
     6661 tctggttttt ggcaatgaga agcagaaggc tttgaagatg ttgaaagaag gtaaaacaaa
     6721 aagtgaaata ttgaaagcga ccggatgtac agttgcggtg aaagatgcga atctttccat
     6781 taatgaaggc gaaatattcg tcattatggg gctgtccggt agtggaaagt ccactttact
     6841 ccgctgcatc aaccgtttga tacgccctac ttccggagaa gtgattatca atggaacaga
     6901 catagccaaa gtgtcggata aggaactgtt gcagattcgc cggaaagaac tggctatggt
     6961 ctttcagaac ttcggtctgc ttcctcaccg ttctgtcttg cataatatag ctttcgggct
     7021 cgaactacag ggagtaaaaa agggagaacg ggagcagaaa gcgatggaaa gtatgcaact
     7081 ggtggggctg aaaggctacg agaatcagat ggtaagtgaa ctgtcgggtg ggatgcagca
     7141 gcgtgtcggg ctggcgcggg ctttggccaa taatcccgaa gtcctgttga tggatgaggc
     7201 cttctcggca ctcgatcctt tgatccgtgt gcagatgcag gatgaactgc tgactttgca
     7261 gtcgaagatg aaaaaaacga ttgtctttat tactcacgac ctgagtgaag cgattaaatt
     7321 gggtgaccgg attgctatca tgaaggatgg agaaattgta caaatcggta catcggaaga
     7381 aatcctgacc gaacctgcca acgcttatgt agaacgattt gtggagaatg tagatcgaag
     7441 caagattata acagcttcct ctgttatggt agataaaccc atagtggcac gtttgaagaa
     7501 agaaggcccg gaggtgctga tccgtaagat gcgcgaacgg aatctgaccg ttcttccggt
     7561 agtcgattcc aataatctgt tagtaggaga ggtgcggttg aatgacttgc tgaaactacg
     7621 aaaagagcaa atccgctcca tcgagtccgt agtaaggcat gaagttcatt cagtgctggg
     7681 tgatacggtg ctggaagata ttcttccgtt gatgacaaaa acgaactcgc caatctgggt
     7741 cgtaaatgag aatcgggagt ttgaaggcgt agtgccactt tcctcattga tcatcgaagt
     7801 aacgggaaaa gataaagaag aaattaatga aatcattcaa aacgcaatag aattatgata
     7861 aatatcggac aatatataga gactgccatt aattggctca cagaacattt tgcttccttt
     7921 tttgatgctc tcagcatggg gatcggagga ttcatagacg gttttcagca cgtactgttt
     7981 ggaatacctt tttatatcac aattgcagtg ctggctgcgc tcgcctggtt taagtcgggt
     8041 aaggggacag ccgtatttac cctcttgggt ttattgctta tttacggcat gggcttttgg
     8101 gaagaaacga tgcagacatt ggcattggta ctttcttcca cttgtctggc attgctttta
     8161 ggcgttccgt tgggaatctg gactgccaac agtgatcgtt gtaacaagat aatgcgccct
     8221 gtcctcgact ttatgcagac aatgcctgcc tttgtctatc tgattcctgc cgttctattc
     8281 ttcggattgg gaactgtgcc gggagctttt gccaccatca tctttgcaat gcctcctgtg
     8341 gttcgtctga ccggtctggg cattcgtcag gttcctaaaa acgtagtaga agcctcccgc
     8401 tcttttggag ctactccctg gcagcttctt tataaggtgc aattgccttt ggcgttgcct
     8461 actattctga cgggaatcaa ccagacgatc atgatgtcac tttcgatggt agtgattgct
     8521 gccatgattt ctgccggagg attgggagaa atcgtgctga aaggtatcac ccaaatgaaa
     8581 atcggactcg gatttgaagg cggtatcgca gtcgtgatat tggcgatcgt gctggaccgc
     8641 atcactcagg gtatggcaga taacagaaaa agtaaaaaga aataagaatc acaccaaaga
     8701 aaggaataat caatgaataa gataaaaatg attgcggcaa tgtttattgc cggcatactc
     8761 ttaaccttcg tttcctgcgg agacaacgga aagagtaaga agataagtat cgcttatgcc
     8821 aactggtcgg aaggtattgc aatgacaaac cttgccaaag cgatttttga agatcagggg
     8881 tacgatgtaa agttgctgaa tgccgacctt gcacctatat ttacctctat ctcccgtaag
     8941 aaagcagacg tatttatgga tgtctggatg cctgtcacta tggaagatta tatgaaacaa
     9001 tacggggata aactcgaagt tatcggggat atttatgatg gtgcccgtat cgggctggtg
     9061 gttccggatt acgttacgat caactcaatc gaagaactga acgcggaaaa ggaacgtttc
     9121 tccggtcaga ttgtcggtat tgatgccgga gccggtatta tgaaagctac cgatcaggcc
     9181 atcaaagact atggattgga ttataaactg atgacttcga gcggacctgc catgactgct
     9241 tccctaaaga aagcgattga taagaaagac tggattgtcg tgacgggatg gacgcctcac
     9301 tggatgttcg accgtttcaa gctgaaagtt cttcaggacc cgaagctgat atatggaaat
     9361 acggaatcca ttcataccat agcatggaaa ggttttagcg agaaagaccc ttttgctgcc
     9421 gaacttttgg gcaacattcg tctgacagat gcggaaatca gctccttaat gactgctctg
     9481 gaagaggcgc agacaacgga aagacaggct gcccgtcaat ggatggaaga acatcaggaa
     9541 ctggtgaaca gttggattcc tgagaaagat tgatatgcaa acactacttc aaccatcccg
     9601 ccattctttc tttaccatag aagtagtaga aaagtagtcc cagccagctg gtaagaacga
     9661 ttaatacaat cgctataagt cttttctcta cagccgcatt tatattccaa atctctatgg
     9721 cagctctgaa agtcagtatc aaaccgataa tccaaataac aaatccgatc atatctttag
     9781 agttttaatg aatatcttcg tgagaagtaa tcgttacttc taagatataa acaaaaaagg
     9841 caggaatctg tttccaggat tcctgccttt tattatgtac aaagtatttc tacttattat
     9901 tcagctgtat cagctcccca gttttctctg gcaagacgtt tgtagctgtt gtaacgccat
     9961 ttagcgtttt cttcagcagc tttaaacagt tcttcagctt cagcaggata ttgtttcatt
    10021 acagaagcgt aacgaacttc acccttcaag aaaccttgga agtcttccca gttaggttct
    10081 ttgctatcca gttggaacgg attcttgcct tcttcttcca aagcagggtt gtaacgccac
    10141 aagtgccagt aaccgcactt aacagccttt tcttcttctt cctggctctt acccataccg
    10201 gctttcagac cgtggttgat acatggagcg taagcgatga tcagtgatgg tcccggatat
    10261 gcttcagctt cacggatagc tttcagagtc tgagcctggt cagcacccat agcaatctga
    10321 gcaacatata cataaccgta agtagtagcc atcagaccga ggtctttctt acgtacacgc
    10381 ttacctgcag cagcaaactt agcgatagcg cctaccggag tagctttaga agactgacca
    10441 cctgtgttag agtaaacctc agtatccaat acaaggatgt taacgtcctt accggaagcg
    10501 attacatggt caagaccacc gtaaccgata tcataagaag caccgtcacc accgatgatc
    10561 cattggctgc gtttaacaag atattgttgc agatcagcga tttgcttgca gtggttgcat
    10621 ttatctttag cagcttctac catcggaatg atcttttcgg ccagttcctt agtcttttct
    10681 gcatccagca tattgttgat ccattcagca aatacttctt tgtattcagc cgggcagcaa
    10741 tcagaagcga tagcttcgtt cattactttc accagacggg cacgcatctt ttcgttagcc
    10801 agttccatac ccagaccaaa ttcacagaag tcttcgaaca aggagttagc ccatgcagga
    10861 ccgtgaccct tttcgttcat agtgtacgga gtagaaggaa ctgaaccgga gtagatagaa
    10921 gaacatcctg tagcgttagc aaccatttca cggtcaccga acaactgaga aatcagtttc
    10981 acgtacggag tttcaccaca accggagcaa gcgcctgaga actcaaacaa cggagttgcg
    11041 aactgagagt tcttcacgtt agccttgatg tctaccaggt gttgtttgct cttcacgttt
    11101 tcagcgcagt aagtccagtt atcagcttcg gccaactggc tttcaaggtg tttcatggtc
    11161 aatgccttgc cacccttctt cggattaccc ggacagatgt cggcacagtt accgcaaccc
    11221 agacaatcga gaacgtctac ctgaatacgg aatgtcatac catcgaatgc tttacctaca
    11281 gctttcagtt gctcgaactt agcacccttc tgctcttcag catcgagtac gaacggacgg
    11341 atagaagcgt gaggacaaac gtaagcacac ttgttacact gaatacagtt ttcagcattc
    11401 cattcgggaa cgaatgcagc tacaccacgt ttttcgtatt tggaagtacc ttgataccaa
    11461 gtaccgtctt cgataccctt gaatgcagat accggcagca agtcaccgtc ctgtgcattg
    11521 atcggacgaa ctacttcgtt gatgaaagca ggatcattgt tttctgcttt tgcatcatcc
    11581 ggcaggttag cccaagcagg atcgacagtc agagtcttgt attcaccacc gcggtctaca
    11641 gcagcgtagt tcttgttaac aacgtcttca cccttcttgc cgtaagactt aacgatgaat
    11701 ttcttcatct gttcaacagc ttgatctaca gggattacgc ctgtgatacg gaagaatgca
    11761 gactgaagga ttgtattggt acggttgccc aaaccaattt ccattgcaat ctgagttgcg
    11821 ttgatatagt atacagagat gttgttctgt gcaaagtatt tcttcacctt gttaggcagg
    11881 ttcttagcca gttcttcgcc ttcccagatg gtattcagca agaaagaacc gttcttacgc
    11941 aaaccacgtg ttacgtcgta catgtgcagg taagcctgaa cgtgacaagc aacgaagttc
    12001 ggagtattta ccaagtaagt agaacggatc ggagtatcac cgaaacgcaa gtgagaacaa
    12061 gtgaaaccac ccgacttctt ggagtcgtaa gagaagtaag cctgacagtg tttgtcggtg
    12121 ttgtcaccga taatcttaac agagttcttg ttggcaccta cagtaccgtc agcacccaga
    12181 ccgtagaatt tagcttcgaa cataccttca ccgcccagag cgatttcttc tttctgagga
    12241 agagaagtga acgtaacgtc gtctacgata ccgatagtga agtggttctt cggcattggc
    12301 atagccaagt tttcgaatac agagatgatc tgtgccggag ttgtatcttt tgaacccaga
    12361 ccgtagcgac cgccaacgat aacaggagca ttttctgcgc catagaagca gtctttaacg
    12421 tcaaggtaaa gaggttcgcc gttagcaccc ggttcttttg tacggtcaag cactgcgatg
    12481 ctctttgcag tcttgggtac agcagccagg aagtgtttag cagagaacgg acgatacaag
    12541 tgtacggcaa ccatacctac tttttcgccg tttgctacca agtggtcgat agcttcgcgg
    12601 gcagcttcag ttacagaacc cattgcgata attacgcgtt ctgcatcttc tgcaccgtag
    12661 taatcgaaca aaccgtattt gcggcctgtg atcttggaaa tttcgttcat gtattcttct
    12721 acgatagcag gaactgcttc atagtagtta ttgcatgatt cacgatgttg gaagaagtgg
    12781 tcggggtttt cagccatacc acgggcaacc ggcttcatcg gattcagtgc acgggcacgg
    12841 aattcagcca aagcttcctg gtcgatcagc ggagcgaggt cgtcgttttc caacatttcg
    12901 atcttctgga tttcgtgaga agtacggaaa ccatcgaaga agttcatgaa cggaacgcgt
    12961 gatttgatag tagccagatg agcaacacct gccaaatcca taacttcctg tacagaacct
    13021 tctgccaaca tagcgaagcc ggtttgacga gctgacatta cgtcctgatg gtcaccgaag
    13081 atacacaatg cgtgagaagc cagtgtacga gcagaaacgt ggaatacaca aggcaagaat
    13141 tcaccggcaa tcttgtacat gttagggatc atcaaaagaa gaccctgaga agcagtgtaa
    13201 gtagtagtca atgcaccagc ctgaagagaa ccgtgaactg caccggcagc accaccttca
    13261 gattgcattt cctgtaccaa tactgtttcg ccgaagatgt tcttacgtcc tgcggcagcc
    13321 cattcgtcta cgtactcagc catagtcgaa gaaggagtga tggggtagat agctgctact
    13381 tcagagaaca tatacgagat atgtgctgca gcttggttac catcacatgt gatgaatttc
    13441 ttctgtttag tcataactaa attaaatatt taagtaaata aatcttttta gtataagaat
    13501 ccgaacatcc aaagaggtat ttggttgccg cggcctatct cagccttttg caacgcatac
    13561 gtcacgtccg ggttattctt tatttttgta ccttccgcac aaattttgaa cggcatcact
    13621 tcgtctacca tgaaagagac gtttttatct cctttatgta ccttatggtc tttccataaa
    13681 gtgttaacga agaacgtgtc gagtacatcc tgttcttcca ctttcaccgg ataaatggag
    13741 tacatcaggt tagagttgtg catcataatc tttgacggtt tctttgggaa ttcttctcct
    13801 ttcgggtaaa ccagattaat cagacgcgcg tctgccagat acttgatata gttcattacc
    13861 gtagcgcggg atgtctgtac gtcacttgcc agttggctca cgttcggagc tttcggtccg
    13921 tccacagcca acaaatatag taattttttt atctttgaaa gatatttcag ctcaatttgt
    13981 ttgatcagca agatatccac ttctaccatc atgttcattg ttttcagcag attctccgag
    14041 aaattacgtt tttcaaggaa gaaagggtag aaaccatgat gcaggtaatc ctgaaaataa
    14101 tccagcggtc gtactttgga aagtactcct ttggctatct gttcatgtgt actgaggatt
    14161 tcttcgaggc tgtatgcccg gaatttcatt cctgtctgca ggttcagaaa ttcacggaaa
    14221 gagaatccgc gcaggttata acttttcgca atgtcacgca attcgaggtt ttcctctttg
    14281 agtcgcatga cggaagaacc ggtgaagaca atcttcaggc tggggaaacg gtcatagcac
    14341 attcgtagct ctttgctcca ttcgggatgt ttgaacacct ggtcgatcag cagtactttt
    14401 ccgccacgtt tctgaaactc gttggcgaag tcaacaaggc tgtgaccgga gaaataaaag
    14461 ttgttcatat tgatgaacag acaggaacgg tcggtgccga atttctcttt ggcgtactgc
    14521 aggaggaaag tggtttttcc tacgccacgt gtccctttga taccaatcag acggtcactc
    14581 cagtcgatct cgtccataag atcgcggcga acgggggcat tggtgtgctc aacgaggtag
    14641 gcgtgtgtgc gatagaatga ttccatttcg tttctttgtt tttcggctgg caaatatagt
    14701 gcttttttta ggatttgcaa agtagagata gcaaaaatgt gctttaattt ataagtttct
    14761 ctttattgtg taagttcctg attatttcct gtatatattt gcagaataat gtgttgaatc
    14821 catctttgac atgacgaaaa gacctgttta tatattcaat ccggagcatg atatggcgtt
    14881 ggcaagcggt gagacgaact atatggcgcc ggcttccgcc cgacagatgg cgagtgacct
    14941 ggcgttgctt cctatgtggt atgccgaagc gggaagtgcg gtgcttgcac cgtctgctta
    15001 taatgcggac ttcctgaaaa caaagagtga acttttgggc atggatgtgg ccttgttgac
    15061 ggaaccggaa gtggctgacg gtaaagaccg gaagttctct ccgtgggggt gggaccctgc
    15121 tttgcggaag cgtttgatga cattgggggc agatcagacg gagctgcctt ctgcggatta
    15181 tatgaatatt ctgagagagc attcgcatcg tctgcaggcg gtaaagttgt tgcctgggtt
    15241 gcggttgaat gaatacttct gtggagaatc tttttatttg agtactttgg cggagtgcag
    15301 tgcgttcgtc gaagggcggg aagcgtgctt gttaaaagct ccgctttccg gaagcgggaa
    15361 aggattgaat tggtgtaaag gcatatttac tacttttatt tccggttggt gtgcccgtgt
    15421 cgctgcttct cagggtgggg tggtaggcga acctatatat aataaggtgg aagatttcgc
    15481 tatggagttt tatgctgacg ggagaggaag ggttgttttt gccggatatt cggtcttcca
    15541 cacgggtggg agtgggatgt atgcagggaa tgacttgctg tctgacgaga agattctgca
    15601 gaaactatcg gcttatgtgc cacaagaaga atttatcagg ctgcggactc gtttggaaga
    15661 agaattgtca gctttgttcg gtggctttta tcatggatac ttgggagtgg atatgatgat
    15721 ttgtcatttt ccggatgaag cgcctgttta ccggattcat ccttgtgtcg aaattaatct
    15781 gcgaatgaat atgggggtgg tggcatggct cttgacggat cgttatttgg ctgcggatgc
    15841 ggaaggagtt tttcggattg attattatcc tttagccggt caggctttgg aggaacatcg
    15901 gcagatgtcg gcttcgttcc ctttgtccgt agagaataat cgggtgtgtg ccggatattt
    15961 gccgttagta ccggtgacgc ctcaaagccg gtatcgtgcg tttcttttgc ttactctccc
    16021 ccagtgaaaa agatagtgct tttgctctca tgctctaaca gttcgtctgt atccctttat
    16081 tcatcgatgt tttagctgtt agagatccag tggtagcaga gtgagagcaa ggacttgctc
    16141 tcactctgca tcgtcctgat aaataccgtt tttactgtgt tattctttga tttacaggat
    16201 gttaatatct gatatctcaa ctgttaacgt ttgatttctc agatattaat aattgagaaa
    16261 tcaagtatta aggactgata atttatgtat tattgactga tatatgattt aatgttttca
    16321 gagagagcag tactattgaa gtagctgatg cgttcaatgt gattggaaca tgcggttaag
    16381 tcaatcaaat caacagtagt ttcagatagt ttcgagcgtt tggaactaaa gtttcaagcg
    16441 tatgaaactc tagtttctca ccgatgaaac tacagtttca caccgatgaa actctggttt
    16501 caagcaatgg aaactctttg aagatactgc taaattggaa ttggtgaaca tcggaaaagt
    16561 catattgtgg taatactgtg tacttcccta ataatggttg acttgtttat ctctaatagc
    16621 tgctatgtgt tgactagaaa tattactaac cctgg
//
